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Antipsychotic drug prescribing and mortality in people with dementia before and during the COVID-19 pandemic: a retrospective cohort study in Wales, UK

Christian Schnier, Aoife McCarthy, Daniel R Morales, Ashley Akbari, Reecha Sofat, Caroline Dale, Rohan Takhar, Mamas A Mamas, Kamlesh Khunti, Francesco Zaccardi, Cathie Sudlow, Tim Wilkinson, on behalf of the CVD-COVID-UK/COVID-IMPACT Consortium

Project description

This project, on behalf of the CVD-COVID-UK consortium, investigates UK antipsychotic medication prescribing trends and mortality in people with dementia. We used time series analyses to compare prescribing trends over a five year period, before and during the COVID-19 pandemic. We also used time series analyses to look at all-cause, cardiovascular and cerebrovascular disease mortality over the same period.

How to cite this work

Schnier C, McCarthy A, Morales DR, et al. Antipsychotic drug prescribing and mortality in people with dementia before and during the COVID-19 pandemic: a retrospective cohort study in Wales, UK. Lancet Healthy Longevity 2023;4(8): e421-e430. doi:10.1016/S2666-7568(23)00105-8

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Project approval

This is a sub-project of project CCU016 approved by the CVD-COVID-UK / COVID-IMPACT Approvals & Oversight Board (sub-project: CCU016_01).

License

Licensed under the Apache License, Version 2.0 (the "License"); you may not use this software except in compliance with the License. You may obtain a copy of the License at http://www.apache.org/licenses/LICENSE-2.0. Unless required by applicable law or agreed to in writing, software distributed under the License is distributed on an "AS IS" BASIS, WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. See the License for the specific language governing permissions and limitations under the License.