From d53493c5990d2a936cf07a6eac5cc6474975bf72 Mon Sep 17 00:00:00 2001
From: Marius <44572437+m-a-r-i-u-s@users.noreply.github.com>
Date: Mon, 16 Sep 2024 15:13:35 +0200
Subject: [PATCH] Update base.py

Check if HMMs are provided if chemical clustering is also required.
---
 domhmm/analysis/base.py | 2 ++
 1 file changed, 2 insertions(+)

diff --git a/domhmm/analysis/base.py b/domhmm/analysis/base.py
index c8e30e3..89ca137 100644
--- a/domhmm/analysis/base.py
+++ b/domhmm/analysis/base.py
@@ -269,6 +269,8 @@ def __init__(
         else:
             # User-specified trained HMM provided, check for consistency with expected format
 
+            assert not any(self.cluster_groups), "Chemical clustering is required, but pre-trained HMMs were provided. Chemical clustering does not require HMMs. Will terminate!"
+
             # Check for assymmetric membrane
             if self.asymmetric_membrane:
                 # Asymmetric membrane functionality was triggered! Assuming same/different lipid types per leaflet