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README.md

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Description

Simulate sets of target and neighbor DNA sequences under a coalescent model with defined markers in the targets. By default, the markers are deleted in the neighbors, but alternatively they can be mutated with a higher rate than the background in the targets. Markers can then be extracted by programs for neighbor-based marker discovery, for example fur. The package contains two programs, stan to simulate targets and neighbors, and rad to randomly delete regions from sequences.

Author

Bernhard Haubold, haubold@evolbio.mpg.de

Make the Programs

Setup the environment by running the script setup.sh, and construct the binaries.

bash scripts/setup.sh
make

The directory bin now contains the binaries rad and stan.

License

GNU General Public License