From 8798ac3312ec21f4bd980e4c92036e79e872155e Mon Sep 17 00:00:00 2001 From: Johannes Hjorth Date: Mon, 24 Jun 2024 14:00:11 +0200 Subject: [PATCH] Added DA syn, test synapse --- data/neurons/mechanisms/DASyn.mod | 38 +++++++++++++++++++++++++++++++ 1 file changed, 38 insertions(+) create mode 100644 data/neurons/mechanisms/DASyn.mod diff --git a/data/neurons/mechanisms/DASyn.mod b/data/neurons/mechanisms/DASyn.mod new file mode 100644 index 0000000..ee1ace9 --- /dev/null +++ b/data/neurons/mechanisms/DASyn.mod @@ -0,0 +1,38 @@ +NEURON { + POINT_PROCESS DASyn + RANGE quanta, tau, open +} +UNITS { + (mM) = (milli / liter) +} + +PARAMETER { + quanta = 1e-4 (mM/ms) + tau = 10 (ms) +} + +INITIAL { + open = 0 +} + +STATE { + open (1) +} + +BREAKPOINT {SOLVE state METHOD cnexp} + +DERIVATIVE state { + open' = -open/tau +} + + +: 33000 dopamine molecules per vesicle : Omiatek, D., Bressler, A., +: Cans, AS. et al. The real catecholamine content of secretory vesicles +: in the CNS revealed by electrochemical cytometry. Sci Rep 3, 1447 +: (2013). https://doi.org/10.1038/srep01447 + + + +NET_RECEIVE(weight) { + open = open + weight +}