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cnov0_5.owl
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cnov0_5.owl
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<?xml version="1.0"?>
<!DOCTYPE rdf:RDF [
<!ENTITY owl "http://www.w3.org/2002/07/owl#" >
<!ENTITY obo "http://purl.obolibrary.org/obo/" >
<!ENTITY swrl "http://www.w3.org/2003/11/swrl#" >
<!ENTITY dc "http://purl.org/dc/elements/1.1/" >
<!ENTITY swrlb "http://www.w3.org/2003/11/swrlb#" >
<!ENTITY xsd "http://www.w3.org/2001/XMLSchema#" >
<!ENTITY snap "http://www.ifomis.org/bfo/1.1/snap#" >
<!ENTITY core "http://www.w3.org/2004/02/skos/core#" >
<!ENTITY ro "http://www.obofoundry.org/ro/ro.owl#" >
<!ENTITY rdfs "http://www.w3.org/2000/01/rdf-schema#" >
<!ENTITY rdf "http://www.w3.org/1999/02/22-rdf-syntax-ns#" >
<!ENTITY protege "http://protege.stanford.edu/plugins/owl/protege#" >
<!ENTITY xsp "http://www.owl-ontologies.com/2005/08/07/xsp.owl#" >
<!ENTITY obo_annot "http://ontology.neuinfo.org/NIF/Backend/OBO_annotation_properties.owl#" >
]>
<rdf:RDF xmlns="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#"
xml:base="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl"
xmlns:dc="http://purl.org/dc/elements/1.1/"
xmlns:ro="http://www.obofoundry.org/ro/ro.owl#"
xmlns:protege="http://protege.stanford.edu/plugins/owl/protege#"
xmlns:xsp="http://www.owl-ontologies.com/2005/08/07/xsp.owl#"
xmlns:snap="http://www.ifomis.org/bfo/1.1/snap#"
xmlns:obo_annot="http://ontology.neuinfo.org/NIF/Backend/OBO_annotation_properties.owl#"
xmlns:obo="http://purl.obolibrary.org/obo/"
xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
xmlns:swrl="http://www.w3.org/2003/11/swrl#"
xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
xmlns:owl="http://www.w3.org/2002/07/owl#"
xmlns:swrlb="http://www.w3.org/2003/11/swrlb#"
xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
xmlns:core="http://www.w3.org/2004/02/skos/core#">
<owl:Ontology rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl">
<dc:date rdf:datatype="&xsd;string">13/03/2012</dc:date>
<dc:subject rdf:datatype="&xsd;string">An ontology to describe the field of Computational Neurosciences</dc:subject>
<dc:contributor rdf:datatype="&xsd;string">Birgit Kriener</dc:contributor>
<dc:title rdf:datatype="&xsd;string">Computational Neuroscience Ontology</dc:title>
<dc:contributor rdf:datatype="&xsd;string">Erik De Schutter</dc:contributor>
<dc:contributor rdf:datatype="&xsd;string">Fahim T. Imam</dc:contributor>
<dc:contributor rdf:datatype="&xsd;string">INCF MultiScale Modeling Task Force</dc:contributor>
<dc:contributor rdf:datatype="&xsd;string">Lars Schwabe</dc:contributor>
<dc:contributor rdf:datatype="&xsd;string">Padraig Gleeson</dc:contributor>
<dc:contributor rdf:datatype="&xsd;string">Sean Hill</dc:contributor>
<dc:contributor rdf:datatype="&xsd;string">Stephen D. Larson</dc:contributor>
<dc:contributor rdf:datatype="&xsd;string">Subhasis Ray</dc:contributor>
<rdfs:comment rdf:datatype="&xsd;string">This ontology is used to add the Definition class of annotation as in NIF.
The source of the definition can be defined with class from OBO-annotation</rdfs:comment>
<rdfs:comment rdf:datatype="&xsd;string">This work is licensed under the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/ or send a letter to Creative Commons, 444 Castro Street, Suite 900, Mountain View, California, 94041, USA.</rdfs:comment>
<dc:creator rdf:datatype="&xsd;string">Yann Le Franc</dc:creator>
<owl:versionInfo rdf:datatype="&xsd;string">version 0.5</owl:versionInfo>
<owl:imports rdf:resource="http://ontology.neuinfo.org/NIF/Backend/OBO_annotation_properties.owl"/>
<owl:imports rdf:resource="http://ontology.neuinfo.org/NIF/Backend/ro_bfo1-1_bridge.owl"/>
<owl:imports rdf:resource="http://protege.stanford.edu/plugins/owl/dc/protege-dc.owl"/>
<owl:imports rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/external_import/external.owl"/>
<owl:imports rdf:resource="http://purl.org/obo/owl/ro"/>
<owl:imports rdf:resource="http://www.ifomis.org/bfo/1.1"/>
<owl:imports rdf:resource="http://www.w3.org/2004/02/skos/core"/>
</owl:Ontology>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Annotation properties
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<owl:AnnotationProperty rdf:about="&obo;IAO_0000115"/>
<owl:AnnotationProperty rdf:about="&obo;IAO_0000119"/>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Datatypes
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Data properties
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000193 -->
<owl:DatatypeProperty rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000193">
<rdfs:label rdf:datatype="&xsd;string">name</rdfs:label>
<rdfs:domain rdf:resource="&snap;GenericallyDependentContinuant"/>
<rdfs:range rdf:resource="&xsd;string"/>
</owl:DatatypeProperty>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000204 -->
<owl:DatatypeProperty rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000204">
<rdfs:label rdf:datatype="&xsd;string">numerical value</rdfs:label>
<rdfs:domain rdf:resource="&snap;GenericallyDependentContinuant"/>
<rdfs:range rdf:resource="&xsd;string"/>
</owl:DatatypeProperty>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Classes
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://ontology.neuinfo.org/NIF/Backend/OBO_annotation_properties.owl#EnumerationClass -->
<rdf:Description rdf:about="&obo_annot;EnumerationClass">
<owl:disjointWith rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000001"/>
<owl:disjointWith rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000002"/>
<owl:disjointWith rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000003"/>
<owl:disjointWith rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000004"/>
<owl:disjointWith rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000040"/>
<owl:disjointWith rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000060"/>
<owl:disjointWith rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000174"/>
<owl:disjointWith rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000175"/>
<owl:disjointWith rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000176"/>
<owl:disjointWith rdf:resource="&core;Collection"/>
<owl:disjointWith rdf:resource="&core;Concept"/>
<owl:disjointWith rdf:resource="&core;ConceptScheme"/>
</rdf:Description>
<!-- http://purl.obolibrary.org/obo/OBI_0001617 -->
<rdf:Description rdf:about="&obo;OBI_0001617">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="&obo;IAO_0000219"/>
<owl:someValuesFrom rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000180"/>
</owl:Restriction>
</owl:equivalentClass>
</rdf:Description>
<!-- http://purl.obolibrary.org/obo/SBO_0000348 -->
<rdf:Description rdf:about="&obo;SBO_0000348">
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000140"/>
</rdf:Description>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000001 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000001">
<rdfs:label rdf:datatype="&xsd;string">defined model type</rdfs:label>
<rdfs:subClassOf rdf:resource="&snap;GenericallyDependentContinuant"/>
<owl:disjointWith rdf:resource="&core;Collection"/>
<owl:disjointWith rdf:resource="&core;Concept"/>
<owl:disjointWith rdf:resource="&core;ConceptScheme"/>
<rdfs:comment rdf:datatype="&xsd;string">This general class includes the most common types of models classified based on the level of description of the nervous system.</rdfs:comment>
<core:definition rdf:datatype="&xsd;string">a generically_dependent_continuant that is a category of models regarded as sharing particular characteristics, qualities, and/or defined similarities.</core:definition>
<core:altLabel rdf:datatype="&xsd;string">defined type of model</core:altLabel>
<rdfs:comment rdf:datatype="&xsd;string">definition based on the following NCI thesaurus entry: http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Type_of_Event</rdfs:comment>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000002 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000002">
<rdfs:label rdf:datatype="&xsd;string">model component</rdfs:label>
<rdfs:subClassOf rdf:resource="&snap;GenericallyDependentContinuant"/>
<owl:disjointWith rdf:resource="&core;Collection"/>
<owl:disjointWith rdf:resource="&core;Concept"/>
<owl:disjointWith rdf:resource="&core;ConceptScheme"/>
<rdfs:comment rdf:datatype="&xsd;string">This class is based on the assumption that models can represented as particular assemblies of components that can be either specific to the different level of description (cellular, synaptic and network) or generic.</rdfs:comment>
<core:definition rdf:datatype="&xsd;string">a generically dependent continuant that is a constituent part of a model</core:definition>
<rdfs:comment rdf:datatype="&xsd;string">definition based on element from NCI Thesaurus: http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Element_Part</rdfs:comment>
<core:altLabel rdf:datatype="&xsd;string">model element</core:altLabel>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000003 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000003">
<rdfs:label rdf:datatype="&xsd;string">parameter</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000147"/>
<owl:disjointWith rdf:resource="&core;Collection"/>
<owl:disjointWith rdf:resource="&core;Concept"/>
<owl:disjointWith rdf:resource="&core;ConceptScheme"/>
<rdfs:comment rdf:datatype="&xsd;string"></rdfs:comment>
<core:definition rdf:datatype="&xsd;string">elementary model component role that defines an elementary model component as constant value determining the characteristics or behaviour of the model</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000004 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000004">
<rdfs:label rdf:datatype="&xsd;string">reset potential</rdfs:label>
<rdfs:subClassOf rdf:resource="&obo;SBO_0000259"/>
<owl:disjointWith rdf:resource="&core;Collection"/>
<owl:disjointWith rdf:resource="&core;Concept"/>
<owl:disjointWith rdf:resource="&core;ConceptScheme"/>
<rdfs:comment rdf:datatype="&xsd;string"></rdfs:comment>
<core:definition rdf:datatype="&xsd;string">value of the membrane potential at which the model is maintained after the emission of a spike.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000005 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000005">
<rdfs:label rdf:datatype="&xsd;string">physical constant</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000181"/>
<obo_annot:definingCitationID>SBO:0000565</obo_annot:definingCitationID>
<obo_annot:definingCitationURI>http://en.wikipedia.org/wiki/Physical_constant</obo_annot:definingCitationURI>
<core:definition>A physical constant that is required in the calculation of a system parameter</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000007 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000007">
<rdfs:label rdf:datatype="&xsd;string">phenomenological plasticity model</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000183"/>
<obo:IAO_0000119 rdf:datatype="&xsd;string">http://www.scholarpedia.org/article/Models_of_synaptic_plasticity</obo:IAO_0000119>
<obo_annot:definingCitationURI rdf:datatype="&xsd;string">http://www.scholarpedia.org/article/Models_of_synaptic_plasticity</obo_annot:definingCitationURI>
<core:definition rdf:datatype="&xsd;string">long term plasticity model that is based on an input-output relationship between neuronal activity and synaptic plasticity. This type of model does not explicitly account for the biochemistry and physiology leading to synaptic plasticity.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000008 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000008">
<rdfs:label rdf:datatype="&xsd;string">cellular model</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000001"/>
<rdfs:comment rdf:datatype="&xsd;string">The distinction between the different subclasses is based on the different "spiking mechanisms".</rdfs:comment>
<core:definition rdf:datatype="&xsd;string">a defined type of model that represent the biological activities of a cell.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000009 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000009">
<rdfs:label rdf:datatype="&xsd;string">synapse model</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000001"/>
<core:definition rdf:datatype="&xsd;string">a defined type of model that represents the biological processes involved in synaptic transmission</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000010 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000010">
<rdfs:label rdf:datatype="&xsd;string">network model</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000001"/>
<core:definition rdf:datatype="&xsd;string">a defined type of model that represents biological neural networks.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000011 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000011">
<rdfs:label rdf:datatype="&xsd;string">plasticity model</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000001"/>
<core:definition rdf:datatype="&xsd;string">a defined type of model that describes the mechanisms underlying the plasticity of the nervous system.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000012 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000012">
<rdfs:label rdf:datatype="&xsd;string">artificial neuron model</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000008"/>
<rdfs:comment rdf:datatype="&xsd;string">This class can be further subdivided into binary neuron, McCullogh neurons and all variants of the artificial neuron models.</rdfs:comment>
<core:definition rdf:datatype="&xsd;string">a cellular model that represents the electrical activity of a nerve cell with simplified function</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000013 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000013">
<rdfs:label rdf:datatype="&xsd;string">point process model</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000008"/>
<rdfs:comment rdf:datatype="&xsd;string"></rdfs:comment>
<core:definition rdf:datatype="&xsd;string">a cellular model that reproduce particular features of real neuron spiking patterns with statistical point process models.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000014 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000014">
<rdfs:label rdf:datatype="&xsd;string">spiking model</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000008"/>
<core:definition rdf:datatype="&xsd;string">a cellular model that describes the mechanism of action potential emission in biological nerve cell.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000015 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000015">
<rdfs:label rdf:datatype="&xsd;string">balanced random network</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000060"/>
<obo_annot:definingCitationID rdf:datatype="&xsd;string">PMID: 10809012</obo_annot:definingCitationID>
<core:definition rdf:datatype="&xsd;string">defined model that corresponds to a network of sparsely connected excitatory and inhibitory neurons which can switch between firing states depending on the balance between excitation and inhibition.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000016 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000016">
<rdfs:label rdf:datatype="&xsd;string">Hopfield network</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000060"/>
<core:definition rdf:datatype="&xsd;string">defined model that is a form of recurrent artificial neural network invented by John Hopfield.</core:definition>
<obo_annot:definingCitationURI rdf:datatype="&xsd;string">http://en.wikipedia.org/wiki/Hopfield_network</obo_annot:definingCitationURI>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000017 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000017">
<rdfs:label rdf:datatype="&xsd;string">biophysical spiking model</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000014"/>
<owl:disjointWith rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000018"/>
<core:definition rdf:datatype="&xsd;string">a spiking model that describe the interactions between the ionic conductances that participates to the generation of an action potential</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000018 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000018">
<rdfs:label rdf:datatype="&xsd;string">threshold-based spiking model</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000014"/>
<core:definition rdf:datatype="&xsd;string">a spiking model that represents the spiking mechanism as the result of a threshold crossing.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000019 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000019">
<rdfs:label rdf:datatype="&xsd;string">reduced model</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000017"/>
<rdfs:comment rdf:datatype="&xsd;string">This class could become a superclass called dynamical models or dynamical system models in contrast with biophysical and threshold based models.
It should contain models like Fitzhugh-Nagumo, Morris-Lecar models.</rdfs:comment>
<core:definition rdf:datatype="&xsd;string">biophysical model that is obtained by dimensionality reduction of a detailed model.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000020 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000020">
<rdfs:label rdf:datatype="&xsd;string">detailed model</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000017"/>
<core:definition rdf:datatype="&xsd;string">biophysical model that describes in detail the conductance variations of the ionic currents responsible of the generation of an action potential</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000021 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000021">
<rdfs:label rdf:datatype="&xsd;string">pulse-based model</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000018"/>
<rdfs:comment rdf:datatype="&xsd;string">This classe refers to detailed integrate-and-fire models as described in Destexhe A. (1997, PMID: 9097470) and Hill S. and Tononi G. (2005, PMID: 15537811) </rdfs:comment>
<core:definition rdf:datatype="&xsd;string">a threshold based spiking neuron model that is an hybrid between Hodgkin and Huxley and integrate-and-fire models. The model describes the impact of fast sodium and delayed rectifier potassium conductances on the subthreshold membrane voltage dynamic and considers action potentials as pulses during which the sodium and potassium conductances are set to particular values representing their participation to the generation and repolarization of the action potential. </core:definition>
<obo:IAO_0000118 rdf:datatype="&xsd;string">conductance-based model</obo:IAO_0000118>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000022 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000022">
<rdfs:label rdf:datatype="&xsd;string">one variable model</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000018"/>
<rdfs:comment rdf:datatype="&xsd;string"></rdfs:comment>
<core:definition rdf:datatype="&xsd;string">a threshold-based model that uses only one variable to describe the nerve cells behavior.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000023 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000023">
<rdfs:label rdf:datatype="&xsd;string">two variable model</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000018"/>
<core:definition rdf:datatype="&xsd;string">a threshold-based model that uses two variables to describe the nerve cells behavior.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000024 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000024">
<rdfs:label rdf:datatype="&xsd;string">three variable model</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000018"/>
<core:definition rdf:datatype="&xsd;string">a threshold-based model that uses three variables to describe the nerve cells behavior</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000025 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000025">
<rdfs:label rdf:datatype="&xsd;string">spike response model</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000018"/>
<core:definition rdf:datatype="&xsd;string">a threshold-based model that correspond to a generalization of the leaky integrate-and-fire model and give a simple description of action potential generation in neurons</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000026 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000026">
<rdfs:label rdf:datatype="&xsd;string">current-based model</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000031"/>
<owl:disjointWith rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000027"/>
<rdfs:comment rdf:datatype="&xsd;string"></rdfs:comment>
<core:definition rdf:datatype="&xsd;string">a model of chemical synapse that consider the impact of the chemical release as a current source in the post-synaptic model with the postsynaptic membrane voltage considered to be constant.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000027 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000027">
<rdfs:label rdf:datatype="&xsd;string">conductance-based model</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000031"/>
<rdfs:comment rdf:datatype="&xsd;string"></rdfs:comment>
<core:definition rdf:datatype="&xsd;string">a model of chemical synapse that consider the impact of the chemical release as a modification of conductance in the post-synaptic model with the post-synaptic potential varying over time.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000028 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000028">
<rdfs:label rdf:datatype="&xsd;string">rate model</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000010"/>
<core:definition rdf:datatype="&xsd;string">network model composed of rate-based neuron models</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000029 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000029">
<rdfs:label rdf:datatype="&xsd;string">artificial neural network model</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000010"/>
<rdfs:comment rdf:datatype="&xsd;string">corresponds to Kohonen maps, Multiple Layer perceptron, ...</rdfs:comment>
<core:definition rdf:datatype="&xsd;string">network model composed of artificial neuron models.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000030 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000030">
<rdfs:label rdf:datatype="&xsd;string">spiking network model</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000010"/>
<core:definition rdf:datatype="&xsd;string">network model that is composed of spiking neuron models.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000031 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000031">
<rdfs:label rdf:datatype="&xsd;string">chemical synapse model</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000009"/>
<owl:disjointWith rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000032"/>
<core:definition rdf:datatype="&xsd;string">a synapse model that describes the impact of chemical compounds released by the synapse</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000032 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000032">
<rdfs:label rdf:datatype="&xsd;string">electrical synapse model</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000009"/>
<core:definition rdf:datatype="&xsd;string">a synapse model that describe synapses transmitting directly ionic currents.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000033 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000033">
<rdfs:label rdf:datatype="&xsd;string">cellular plasticity model</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000011"/>
<rdfs:comment rdf:datatype="&xsd;string">This class would contains models that describes the link between potassium channels and NMDA activation as described in hippocampus for instance.</rdfs:comment>
<core:definition rdf:datatype="&xsd;string">plasticity model that describes the variations of the cellular intrinsic excitability due to regulation of ionic conductances depending on the network activity.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000034 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000034">
<rdfs:label rdf:datatype="&xsd;string">synaptic plasticity model</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000011"/>
<core:definition rdf:datatype="&xsd;string">model of plasticity that represents the mechanisms underlying changes in synaptic transmission, depending on the network or cellular activity.</core:definition>
<core:altLabel rdf:datatype="&xsd;string">synaptic plasticity rule</core:altLabel>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000035 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000035">
<rdfs:label rdf:datatype="&xsd;string">short term facilitation model</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000182"/>
<core:definition rdf:datatype="&xsd;string">a model of short term synaptic plasticity that represents the increase of the synaptic efficacy for a short period of time.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000036 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000036">
<rdfs:label rdf:datatype="&xsd;string">cellular model component</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000218"/>
<core:definition rdf:datatype="&xsd;string">aggregated model composed that is used to build cellular models</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000037 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000037">
<rdfs:label rdf:datatype="&xsd;string">synapse model component</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000218"/>
<core:definition rdf:datatype="&xsd;string">aggregated model component that is used to build synaptic models.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000038 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000038">
<rdfs:label rdf:datatype="&xsd;string">resting membrane potential</rdfs:label>
<rdfs:subClassOf rdf:resource="&obo;SBO_0000259"/>
<rdfs:comment rdf:datatype="&xsd;string"></rdfs:comment>
<core:definition rdf:datatype="&xsd;string">value of the neuronal membrane potential at rest</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000039 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000039">
<rdfs:label rdf:datatype="&xsd;string">refractory mechanism</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000036"/>
<rdfs:comment rdf:datatype="&xsd;string">This is a general term that encompass the refractory period usually defined with a time constant and the resetting of the membrane potential during the refractory period.</rdfs:comment>
<core:definition rdf:datatype="&xsd;string">a cellular model component that represents the mechanism by which the model is kept unresponsive to any stimulus after the emission of an action potential.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000040 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000040">
<rdfs:label rdf:datatype="&xsd;string">model quality</rdfs:label>
<rdfs:subClassOf rdf:resource="&snap;Quality"/>
<owl:disjointWith rdf:resource="&core;Collection"/>
<owl:disjointWith rdf:resource="&core;Concept"/>
<owl:disjointWith rdf:resource="&core;ConceptScheme"/>
<core:definition rdf:datatype="&xsd;string">quality that represents a qualitative feature of the model that can be either independent of the model specification or a property resulting of the particular model specification</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000041 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000041">
<rdfs:label rdf:datatype="&xsd;string">spiking mechanism</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000036"/>
<core:definition rdf:datatype="&xsd;string">a cellular model component that represents the mechanisms generating action potential in a cellular model type.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000042 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000042">
<rdfs:label rdf:datatype="&xsd;string">morphology</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000036"/>
<core:definition rdf:datatype="&xsd;string">a cellular model component that represents the morphology of the model</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000043 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000043">
<rdfs:label rdf:datatype="&xsd;string">intracellular dynamic</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000036"/>
<core:definition rdf:datatype="&xsd;string">a cellular model component that represents a chemical signaling occuring inside the nerve cell</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000044 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000044">
<rdfs:label rdf:datatype="&xsd;string">stimulation current</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000126"/>
<core:definition rdf:datatype="&xsd;string">current model that represents input currents provided to the model via an electrode (intracellular or extracellular).</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000045 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000045">
<rdfs:label rdf:datatype="&xsd;string">generic model component</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000218"/>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000046 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000046">
<rdfs:label rdf:datatype="&xsd;string">probabilistic component</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000045"/>
<core:definition rdf:datatype="&xsd;string">a generic model component that represents the probabilistic variations of any model component.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000047 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000047">
<rdfs:label rdf:datatype="&xsd;string">ionic current model</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000126"/>
<core:definition rdf:datatype="&xsd;string">a current model that describes the flow of ions through cellular membrane.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000048 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000048">
<rdfs:label rdf:datatype="&xsd;string">synaptic current</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000126"/>
<core:definition rdf:datatype="&xsd;string">current model that represents the flow of ions triggered by the activation of a chemical or electrical synapse model.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000049 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000049">
<rdfs:label rdf:datatype="&xsd;string">abstract current model</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000126"/>
<core:definition rdf:datatype="&xsd;string">a current model that is an abtraction of complex current interactions and which is used to reproduce a particular cellular behavior such as rebound or adaptation.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000050 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000050">
<rdfs:label rdf:datatype="&xsd;string">continuous</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000041"/>
<rdfs:comment rdf:datatype="&xsd;string"></rdfs:comment>
<core:definition rdf:datatype="&xsd;string">a spiking mechanism that considers the action potential initiation as a continuous process often based on the non linearity of the conductance changes supporting the initiation of an action potential. This mechanism is the opposite of a threshold-based mechanisms.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000051 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000051">
<rdfs:label rdf:datatype="&xsd;string">threshold-based</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000041"/>
<core:definition rdf:datatype="&xsd;string">a spiking mechanism that considers the action potential initiation as a result of a thresholding operation.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000052 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000052">
<rdfs:label rdf:datatype="&xsd;string">point</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000042"/>
<core:definition rdf:datatype="&xsd;string">a morphology that is used to represents the models without specified geometry.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000053 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000053">
<rdfs:label rdf:datatype="&xsd;string">single compartment</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000042"/>
<core:definition rdf:datatype="&xsd;string">a morphology that consider the cellular morphology as a unique compartment</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000054 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000054">
<rdfs:label rdf:datatype="&xsd;string">multiple compartment</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000042"/>
<core:definition rdf:datatype="&xsd;string">a morphology that represents the modeled cell with multiple compartments. This morphology spans the models called the Ball-and-stick model and the models based on reconstructed morphologies.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000055 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000055">
<rdfs:label rdf:datatype="&xsd;string">reconstructed</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000165"/>
<rdfs:comment rdf:datatype="&xsd;string"></rdfs:comment>
<core:definition rdf:datatype="&xsd;string">morphological quality that represents model morphologies build upon the reconstruction of a real nerve cell morphology using imaging techniques such as camera lucida or two-photon imaging.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000056 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000056">
<rdfs:label rdf:datatype="&xsd;string">calcium dynamic</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000043"/>
<core:definition rdf:datatype="&xsd;string">an intracellular dynamic model component that represents the variation of the intracellular calcium concentration over time.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000057 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000057">
<rdfs:label rdf:datatype="&xsd;string">biochemical dynamic</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000043"/>
<rdfs:comment rdf:datatype="&xsd;string">NOTE: Shouldn't be separated from calcium dynamic as calcium is also a molecular participant. One possible solution would be to change into: reduced calcium dynamic to represent the simplification of buffering and detailed biochemical reactions that details the calcium buffering!!!</rdfs:comment>
<core:definition rdf:datatype="&xsd;string">an intracellular dynamic model component that represents the dynamic of the intracellular biochemical reactions and molecular participant concentrations over time.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000058 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000058">
<rdfs:label rdf:datatype="&xsd;string">network model component</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000218"/>
<core:definition rdf:datatype="&xsd;string">a model component that is used to build network model types.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000059 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000059">
<rdfs:label rdf:datatype="&xsd;string">non linear spike generation current</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000049"/>
<core:definition rdf:datatype="&xsd;string">abstract current model that represents an additional non-linear current ψ which leads to a divergence of the potential toward infinity in a finite time during the emission of an action potential.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000060 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000060">
<rdfs:label rdf:datatype="&xsd;string">defined model</rdfs:label>
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="&ro;has_part"/>
<owl:someValuesFrom rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000002"/>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="&snap;GenericallyDependentContinuant"/>
<owl:disjointWith rdf:resource="&core;Collection"/>
<owl:disjointWith rdf:resource="&core;Concept"/>
<owl:disjointWith rdf:resource="&core;ConceptScheme"/>
<core:definition rdf:datatype="&xsd;string">a generically_dependent_continuant that represent the set of models commonly used to build other models.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000061 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000061">
<rdfs:label rdf:datatype="&xsd;string">integrate-and-fire</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000060"/>
<core:definition rdf:datatype="&xsd;string">a defined model that represent the evolution of voltage as the derivative of the law of capacitance. The action potential is emitted when the value of the voltage reaches a threshold and is considered as Dirac function. After the emission the voltage is resetted to the resting potential value.</core:definition>
<obo_annot:definingCitationURI rdf:datatype="&xsd;string">http://en.wikipedia.org/wiki/Biological_neuron_model#Integrate-and-fire</obo_annot:definingCitationURI>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000062 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000062">
<rdfs:label rdf:datatype="&xsd;string">adaptive exponential integrate-and-fire</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000060"/>
<obo_annot:synonym rdf:datatype="&xsd;string">AdEx</obo_annot:synonym>
<core:definition rdf:datatype="&xsd;string">a defined model that is a spiking neuron model with two variables. The first equation describes the dynamics of the membrane potential and includes an activation ter with an exponential voltage dependence. Voltage is coupled to a second equation which describes adaptation. Both variables are reset if an action potential has been triggered. This model has been introduced by Brette and Gerstner in 2005.</core:definition>
<obo_annot:definingCitationURI rdf:datatype="&xsd;string">http://www.scholarpedia.org/article/Adaptive_exponential_integrate-and-fire_model</obo_annot:definingCitationURI>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000063 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000063">
<rdfs:label rdf:datatype="&xsd;string">independent variable</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000219"/>
<obo_annot:definingCitationURI rdf:datatype="&xsd;string">http://en.wikipedia.org/wiki/Variable_(mathematics)</obo_annot:definingCitationURI>
<core:definition rdf:datatype="&xsd;string">variable regarded as inputs to a system and may take on different values freely</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000064 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000064">
<rdfs:label rdf:datatype="&xsd;string">dependent variable</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000219"/>
<obo_annot:definingCitationURI rdf:datatype="&xsd;string">http://en.wikipedia.org/wiki/Variable_(mathematics)</obo_annot:definingCitationURI>
<core:definition rdf:datatype="&xsd;string">variable regarded as values that change as a consequence of changes in other values in the system.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000065 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000065">
<rdfs:label rdf:datatype="&xsd;string">exponential integrate-and-fire</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000060"/>
<obo_annot:synonym rdf:datatype="&xsd;string">EIF</obo_annot:synonym>
<core:definition rdf:datatype="&xsd;string">a defined model that is an integrate-and-fire model in which the action potentials are generated by an exponential current instead of a fixed threshold. The exponential integrate-and-fire model is defined in Fourcaud-Trocme and al. 2003</core:definition>
<obo_annot:definingCitationURI rdf:datatype="&xsd;string">w.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1001056</obo_annot:definingCitationURI>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000066 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000066">
<rdfs:label rdf:datatype="&xsd;string">leaky integrate-and-fire</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000060"/>
<obo_annot:synonym rdf:datatype="&xsd;string">LIF, Lapicque's model</obo_annot:synonym>
<core:definition rdf:datatype="&xsd;string">a defined model that is an integrate-and-fire model with a leak component added to the membrane potential, reflecting the diffusion of ions that occurs through the membrane when some equilibrium is not reached in the cell.</core:definition>
<obo_annot:definingCitationURI rdf:datatype="&xsd;string">http://en.wikipedia.org/wiki/Biological_neuron_model#Leaky_integrate-and-fire</obo_annot:definingCitationURI>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000067 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000067">
<rdfs:label rdf:datatype="&xsd;string">quadratic integrate-and-fire</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000060"/>
<obo_annot:synonym rdf:datatype="&xsd;string">QIF</obo_annot:synonym>
<core:definition rdf:datatype="&xsd;string">a defined model that is an integrate-and-fire model in which the action potentials are generated by a quadratic current instead of a fixed threshold. The quadratic integrate-and-fire model is defined in Latham and al. 2000. This model is identical to the Theta neuron proposed by Ermentrout and Kopell (1986) with a variable change.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000068 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000068">
<rdfs:label rdf:datatype="&xsd;string">theta neuron model</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000060"/>
<core:definition rdf:datatype="&xsd;string">a defined model that is well suited to describe the processes involving rapid changes in membrane potential, known as bursts. The theta model describes parabolic bursting and has been defined in Ermentrout and Kopell, SIAM journal of Applied Mathematics 1986.</core:definition>
<obo_annot:definingCitationURI rdf:datatype="&xsd;string">http://en.wikipedia.org/wiki/Theta_model</obo_annot:definingCitationURI>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000069 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000069">
<rdfs:label rdf:datatype="&xsd;string">adaptive integrate-and-fire</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000060"/>
<obo_annot:synonym rdf:datatype="&xsd;string">ALIF</obo_annot:synonym>
<core:definition rdf:datatype="&xsd;string">a defined model that is a two-variable integrate-and-fire model. The second variable accounts for the currents involved in spike frequency adaptation. This variable increase transiently during action potentials and decay between action potential.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000070 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000070">
<rdfs:label rdf:datatype="&xsd;string">generalized integrate-and-fire</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000060"/>
<obo_annot:synonym rdf:datatype="&xsd;string">GIF</obo_annot:synonym>
<obo_annot:definingCitationID rdf:datatype="&xsd;string">PMID: 12611957</obo_annot:definingCitationID>
<core:definition rdf:datatype="&xsd;string">a defined model that is a two variable integrate-and-fire model with a threshold for spike generation and a reset as in the leaky integrate-and-fire model. The two variables represent subthreshold resonance behavior and result from the linearization of the Hodgkin and Huxley equation around a subthreshold holding potential. This model is similar to the resonate-and-fire model proposed by Izhikevich (2001)</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000071 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000071">
<rdfs:label rdf:datatype="&xsd;string">integrate-and-fire-or-burst</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000060"/>
<obo_annot:synonym rdf:datatype="&xsd;string">IFB</obo_annot:synonym>
<core:definition rdf:datatype="&xsd;string">a defined model that is a two-variable integrate-and-fire model. The second variable is a slow variable that represents the inactivation of the low-threshold calcium current. This model reproduces the features of the bursting behavior of thalamo-cortical relay neurons and has been proposed by Smith and al., 2000</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000072 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000072">
<rdfs:label rdf:datatype="&xsd;string">Izhikevich model</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000060"/>
<obo_annot:definingCitationID rdf:datatype="&xsd;string">PMID: 18244602</obo_annot:definingCitationID>
<core:definition rdf:datatype="&xsd;string">a defined model that is a minimal two-variable integrate-and-fire model that reproduces different features depending on the value of 4 parameters. The second variable represents the adaptation. This model has been proposed in Izhikevich, 2003.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000073 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000073">
<rdfs:label rdf:datatype="&xsd;string">resonate-and-fire</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000060"/>
<obo_annot:definingCitationID rdf:datatype="&xsd;string">PMID: 11665779</obo_annot:definingCitationID>
<core:definition rdf:datatype="&xsd;string">a defined model that is a two variable integrate-and-fire model proposed by Izhikevich in Izhikevich, 2001.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000074 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000074">
<rdfs:label rdf:datatype="&xsd;string">HindMarch and Rose model</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000060"/>
<obo_annot:definingCitationID rdf:datatype="&xsd;string">PMID: 6144106</obo_annot:definingCitationID>
<core:definition rdf:datatype="&xsd;string">a defined model that is a three-variable model: the membrane potential written in dimensionless unit, the spiking variable that represent the fast transport of sodium and potassium ions and the bursting variable that represent the slow transport of other ions. This model aims to study the spiking-bursting behavior of the membrane potential observed in experiments.</core:definition>
<obo_annot:definingCitationURI rdf:datatype="&xsd;string">http://en.wikipedia.org/wiki/Hindmarsh%E2%80%93Rose_model</obo_annot:definingCitationURI>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000075 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000075">
<rdfs:label rdf:datatype="&xsd;string">Rotstein model</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000060"/>
<obo_annot:definingCitationID rdf:datatype="&xsd;string">PMID: 16927211</obo_annot:definingCitationID>
<core:definition rdf:datatype="&xsd;string">a defined model that is three variable reduced model defined in Rotstein and al. 2006 in J. Comp. Neurosci.</core:definition>
</owl:Class>
<!-- http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000076 -->
<owl:Class rdf:about="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000076">
<rdfs:label rdf:datatype="&xsd;string">Shinomoto model</rdfs:label>
<rdfs:subClassOf rdf:resource="http://purl.org/incf/ontology/Computational_Neurosciences/cno_alpha.owl#cno_0000060"/>
<obo_annot:definingCitationID rdf:datatype="&xsd;string">PMID: 20478693</obo_annot:definingCitationID>
<core:definition rdf:datatype="&xsd;string">a defined model that is a multi-timescale adaptive threshold model of neuronal spiking incorporated into the stochastic framework of the linear-nonlinear Poisson model in the form of a generalized linear model.</core:definition>
</owl:Class>