diff --git a/CMakeLists.txt b/CMakeLists.txt
index 6502b0911..e8f39f745 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -60,6 +60,9 @@ if (CMAKE_Fortran_COMPILER_ID STREQUAL "GNU")
     if (CMAKE_Fortran_COMPILER_VERSION VERSION_LESS 5)
         message(FATAL_ERROR "${__err_msg}ERROR: GNU v5.0 or newer is required to build MFC.")
     endif()
+    if (MFC_OpenACC)
+        message(FATAL_ERROR "${__err_msg}ERROR: MFC with GPU processing is not currently compatible with GNU compilers. Please use NVIDIA or Cray compilers.")
+    endif()
 elseif ((CMAKE_Fortran_COMPILER_ID STREQUAL "NVHPC") OR (CMAKE_Fortran_COMPILER_ID STREQUAL "PGI"))
     if (CMAKE_Fortran_COMPILER_VERSION VERSION_LESS 21.7)
         message(FATAL_ERROR "${__err_msg}ERROR: NVHPC v21.7 or newer is required to build MFC.")