How are single breakends handled

[eesiribloom]

I noticed that many single breakends detected by severus had been removed when generating ensemble VCF files.

Are all single breakend variants removed by minda, even if supported by another SV caller such as nanomonsv?

How would you recommend handling single breakends in this case?

[asherbryant]

Hello @eesiribloom - Yes, all singletons are removed to enable fair comparison as most callers do not output singletons. This will be updated to be an optional feature in the near future.