diff --git a/.coveragerc b/.coveragerc
index 0821bd76..c618911f 100644
--- a/.coveragerc
+++ b/.coveragerc
@@ -1,7 +1,5 @@
 [run]
 branch = True
-omit =
-    setup.py
 
 [paths]
 source =
diff --git a/.github/workflows/cis.yml b/.github/workflows/cis.yml
index de1c476c..28c6ed7c 100644
--- a/.github/workflows/cis.yml
+++ b/.github/workflows/cis.yml
@@ -13,7 +13,6 @@ on:
       - "src/**"
       - "tests/*"
       - pyproject.toml
-      - setup.py
       - tox.ini
 
 jobs:
diff --git a/.github/workflows/docs.yml b/.github/workflows/docs.yml
index 842db333..bd573bdc 100644
--- a/.github/workflows/docs.yml
+++ b/.github/workflows/docs.yml
@@ -13,7 +13,6 @@ on:
       - "src/**"
       - "doc/**"
       - pyproject.toml
-      - setup.py
 
 jobs:
   docs:
diff --git a/.github/workflows/frameworks.yml b/.github/workflows/frameworks.yml
index 9376c6d7..3b924df7 100644
--- a/.github/workflows/frameworks.yml
+++ b/.github/workflows/frameworks.yml
@@ -12,7 +12,6 @@ on:
       - "src/**"
       - "tests/frameworks/*"
       - pyproject.toml
-      - setup.py
       - tox.ini
 
 jobs:
diff --git a/pyproject.toml b/pyproject.toml
index 217d1541..789c5a02 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -61,17 +61,19 @@ __version__ = "{version}"
 
 [tool.ruff]
   src = ["src"]
-  select = ["B", "C", "E", "F", "W", "B9", "I", "C90", "RUF"]
   extend-exclude = ["tests/instruments/hardware/nifpga/scope_based"]
-  extend-ignore = ["E203", "E266", "E501", "F403", "F401", "RUF012"]
   line-length = 88
 
-  [tool.ruff.isort]
-    combine-as-imports = true
-    extra-standard-library = ["opcode"]
+  [tool.ruff.lint]
+    select = ["B", "C", "E", "F", "W", "B9", "I", "C90", "RUF"]
+    extend-ignore = ["E203", "E266", "E501", "F403", "F401", "RUF012"]
 
-  [tool.ruff.mccabe]
-    max-complexity = 42
+    [tool.ruff.lint.isort]
+      combine-as-imports = true
+      extra-standard-library = ["opcode"]
+
+    [tool.ruff.lint.mccabe]
+      max-complexity = 42
 
 [tool.mypy]
   follow_imports = "normal"
diff --git a/setup.py b/setup.py
deleted file mode 100644
index 22ffbcf7..00000000
--- a/setup.py
+++ /dev/null
@@ -1,27 +0,0 @@
-#!/usr/bin/env python3
-
-# Prepare a release:
-#
-#  - git pull --rebase
-#  - run tests: tox
-#  - set release date in the changelog
-#  - git commit -a
-#  - git push
-#  - check GHA CI status:
-#    https://github.com/MatthieuDartiailh/bytecode/actions
-#
-# Release a new version:
-#
-#  - git tag VERSION
-#  - git push --tags
-#
-# After the release:
-#
-#  - set version to n+1
-#  - git commit -a -m "post-release"
-#  - git push
-
-from setuptools import setup
-
-if __name__ == "__main__":
-    setup()
diff --git a/tox.ini b/tox.ini
index a77d9362..7fba64ae 100644
--- a/tox.ini
+++ b/tox.ini
@@ -15,7 +15,7 @@ deps=
     ruff
 commands =
     ruff src/bytecode tests
-    ruff format --check src/bytecode tests setup.py
+    ruff format --check src/bytecode tests
 
 [testenv:lint]
 basepython = python3
@@ -24,7 +24,7 @@ deps=
     mypy
 commands =
     ruff src/bytecode tests
-    ruff format --check src/bytecode tests setup.py
+    ruff format --check src/bytecode tests
     mypy src tests
 
 [testenv:docs]