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Stricter filters increasing differentially expressed proteins? #31

Closed Answered by hsiaoyi0504
Mrfa0811 asked this question in Q&A
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@Mrfa0811 I don't think there is no statistical guarantee of how many differential expressed genes or proteins if you increase the filter. The factor you didn't mention is about the multiple testing correction. The strict filter could lead to less features subjected to the differential expression analysis, but then it might pass multiple testing correction easier.

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