In this repository the electronic package for qualification of CYP2C8 ontogeny using in vivo probe substances are stored, including
- Input files (qualification plan, report text modules and observed data)
For the Qualification of the CYP2C8 mediated elimination of compounds, the following probe substance was included:
- Montelukast [1]
Necessary software to execute the qualification workflow (see http://setup.open-systems-pharmacology.org for download links and instructions):
- QualificationRunner
- Reporting-Engine
- Markdown-joiner
[1] Montelukast-Model, Whole-body PBPK model of Montelukast.