In this repository the electronic package for qualification of UGT1A1 ontogeny using in vivo probe substances are stored, including
- Input files (qualification plan, report text modules and observed data)
- Qualification Report
For the Qualification of the UGT1A1 mediated elimination of compounds, the following probe substance was included:
- Raltegravir [1]
Necessary software to execute the qualification workflow (see http://setup.open-systems-pharmacology.org for download links and instructions):
- QualificationRunner
- Reporting-Engine
- Markdown-joiner
[1] Raltegravir-Model, Whole-body PBPK model of Raltegravir.