Some pregnancy-specific compartments use heart formula to calculate surface area (interstitial/intracellular)

[AndreDlm]

The compartments AmnioticFluid, Breasts, PlacentaMaternal, PlacentaFetal and Fetus use the heart formula to calculate the surface area (interstitial/intracellular).
While the formula refers to the correct organ volume for surface area calculation (FIRST_NEIGHBOR|..|Volume), the numerical coefficients in the formula may be different for the pregnancy-specific organs, although difficult to tell without morphological/stereological tissue data...
Anyway, this remains an assumption that should be known when using the spatial structure.

E.g. for the fetus:

[mmalsmadi]

Hello

I am trying to build a pregnancy model that I started in PK-Sim, sent to MoBi
Then in MoBi I did the following all the steps advised in "Applied Concepts in PBPK Modeling: How to Extend an Open Systems Pharmacology Model to the Special Population of Pregnant Women"

Finally, when I tried to put the simulation together in MoBi, I got the following error message

When tracked the path down I found the following set of parameters

I went back to check the PkSim file for the related nonpregnant model, and these were the values

attached are the files I am working on

1983 Justins Mother IM.zip
Can you please help me sort out this issue?

Thanks
Mo'tasem