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Cotyledon Perfusion Model: Error when trying to run a simulation in the MoBi file for the Cotyledon Perfusion Model #29

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SoFiHo05 opened this issue Oct 29, 2024 · 0 comments

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@SoFiHo05
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Hi,
when trying to understand the Cotyledon Perfusion Model I wanted to run the simulations in the file, which was not possible due to the following error:
image

What I think causes the issue is the following: The drug parameter Blood/Plasma concentration ratio is set to 0 under "User Defined", which results in the partition coefficient (blood cell/plasma) becoming negative
image

I was able to run the simulation after creating a new molecule, which seems to use another formula for calculating the partition coefficient (blood cell/plasma).
Could this be a version issue?
Is it necessary to set the parameter Blood/Plasma concentration ratio to 0?

Thank you for your help!

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