From f8493f4bcf081e59bed73b168d7d4af8bcb57261 Mon Sep 17 00:00:00 2001 From: Sebastian Frechen Date: Fri, 5 Jun 2020 12:13:28 +0200 Subject: [PATCH] typo corrected in link to repo --- Qualification/Input/Content/Rifampicin-Alfentanil-DDI.md | 4 ++-- 1 file changed, 2 insertions(+), 2 deletions(-) diff --git a/Qualification/Input/Content/Rifampicin-Alfentanil-DDI.md b/Qualification/Input/Content/Rifampicin-Alfentanil-DDI.md index fd8aff6..37969a5 100644 --- a/Qualification/Input/Content/Rifampicin-Alfentanil-DDI.md +++ b/Qualification/Input/Content/Rifampicin-Alfentanil-DDI.md @@ -1,5 +1,5 @@ The release of the snapshot containing the respective simulations can be found here: -https://github.com/Open-Systems-Pharmacology/Rifampicn-Alfentanil-DDI/releases/tag/v1.0. +https://github.com/Open-Systems-Pharmacology/Rifampicin-Alfentanil-DDI/releases/tag/v1.0. The rifampicin / midazolam interaction was evaluated using 5 clinical DDI studies including 16 different clinical settings ([Kharasch 1997](#4-References), [Kharasch 2004](#4-References), [Kharasch 2011](#4-References), [Kharasch 2011b](#4-References), [Phimmasone 2001](#4-References)). @@ -20,4 +20,4 @@ The rifampicin / midazolam interaction was evaluated using 5 clinical DDI studi | 771 | CYP3A4 | Rifampicin / alfentanil | Rifampicin: **600** mg po once daily (6 doses)
Alfentanil: 4 mg **PO** single dose, **15** h after **5th** rifampicin dose | sequential administration of intravenous unlabeled alfentanil and oral deuterated alfentanil | [Kharasch 2011b](#4-References) | | 767 | CYP3A4 | Rifampicin / alfentanil | Rifampicin: **600** mg po once daily (6 doses)
Alfentanil: 1 mg **IV** single dose, **12** h after **6th** rifampicin dose | simultaneous administration of intravenous unlabeled alfentanil and oral deuterated alfentanil | [Kharasch 2011b](#4-References) | | 775 | CYP3A4 | Rifampicin / alfentanil | Rifampicin: **600** mg po once daily (6 doses)
Alfentanil: 4 mg **PO** single dose, **12** h after **XXth** rifampicin dose | simultaneous administration of intravenous unlabeled alfentanil and oral deuterated alfentanil | [Kharasch 2011b](#4-References) | -| 391 | CYP3A4 | Rifampicin / alfentanil | Rifampicin: **600** mg po once daily (5 doses)
Alfentanil: 15 µg/kg **IV** single dose, **11** h after **5th** rifampicin dose | | [Phimmasone 2001](#4-References) | \ No newline at end of file +| 391 | CYP3A4 | Rifampicin / alfentanil | Rifampicin: **600** mg po once daily (5 doses)
Alfentanil: 15 µg/kg **IV** single dose, **11** h after **5th** rifampicin dose | | [Phimmasone 2001](#4-References) |