From 6749fa114e42d5099fa450129e4c1fdf059c9f2a Mon Sep 17 00:00:00 2001
From: Elisabeth Waczek <140592956+EWaczek@users.noreply.github.com>
Date: Thu, 14 Nov 2024 12:19:37 +0100
Subject: [PATCH] add missing term
---
cntr-monitor/content/en/issues/2024/posts/8_oncolytic.mdx | 2 +-
1 file changed, 1 insertion(+), 1 deletion(-)
diff --git a/cntr-monitor/content/en/issues/2024/posts/8_oncolytic.mdx b/cntr-monitor/content/en/issues/2024/posts/8_oncolytic.mdx
index 4426f2e4..ac6f0b24 100644
--- a/cntr-monitor/content/en/issues/2024/posts/8_oncolytic.mdx
+++ b/cntr-monitor/content/en/issues/2024/posts/8_oncolytic.mdx
@@ -39,7 +39,7 @@ While viral engineering may be crucial for developing effective therapeutics, th
## Choice of Virus for Oncolytic Virotherapy
-The dual-use potential of oncolytic virus research depends on how directly viral engineering insights may be applied to pathogens. Thus, the choice of viral vectors significantly influences dual-use risk. In contrast to other therapeutic applications of viruses, for instance for gene therapy, there is a particularly high chance of oncolytic virus research involving viruses related to human pathogens. An effective oncolytic virus can replicate in humans, have cancer-killing activity, and induce immune responses that can kill bystander tumor cells. Thus, among the ten virus families explored in clinical trials of oncolytic virotherapy are high-risk viruses such as the influenza, measles, and variola viruses (see Table 1). Influenza and measles viruses are both human pathogens against which a significant share of the population is immunized. Insights into the enhancement of these viruses, especially relating to the property of evading vital immune responses, could pose significant public health risks.
+The dual-use potential of oncolytic virus research depends on how directly viral engineering insights may be applied to pathogens. Thus, the choice of viral vectors significantly influences dual-use risk. In contrast to other therapeutic applications of viruses, for instance for gene therapy, there is a particularly high chance of oncolytic virus research involving viruses related to human pathogens. An effective oncolytic virus can replicate in humans, have cancer-killing activity, and induce immune responses that can kill bystander tumor cells. Thus, among the ten virus families explored in clinical trials of oncolytic virotherapy are high-risk viruses such as the influenza, measles, and variola viruses (see Table 1). Influenza and measles viruses are both human pathogens against which a significant share of the population is immunized. Insights into the enhancement of these viruses, especially relating to the property of evading vital immune responses, could pose significant public health risks.