Question regarding extractSignatures command #645
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Hi @PoisonAlien, maftools package is brilliant. Have a small question about Since you are using |
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Replies: 2 comments 2 replies
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Hello, Also, you are welcome to test this by adding Hope this helps. |
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There is a function [doc, source code] |
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Hello,
Thanks for using
maftools
and I am glad that you find it useful.In my experience
nrun
has an insignificant influence on the overall results. The critical step isestimateSignatures
and as long as you have this approximation, it should be fine for the mainextractSignatures
.nrun
indeed helps when the data has lots of observation (as in DNAm or gene expression), since here there are only 96 channels, it should not affect the results much.Also, you are welcome to test this by adding
nrun = 100
to this line of theextractSignatures
script :)Hope this helps.