Various segmentation tools are available, from basic manual contouring, to thresholding and more advanced automated tools.
For segmenting the lesion in PET, we will use a specialized automated tool presented by Beichel et al in this manuscript.
To segment a PET lesion using this tool, first enable it from the list of segmentation tools, and then click within the primary lesion region in the axial slice.
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Try it yourself: Repeat the same sequence of steps to segment the Secondary lesion!