This page is where developers can collect benchmark results for various Rosetta protocols with beta_nov15 energy function. The main aim is to check any improvements or degradations in scientific performances before we switch our default energy function from talaris2014 to beta_nov15. Please make sure the items below are properly described when you contribute here.
Please refer to http://www.tablesgenerator.com/markdown_tables to make/edit tables. Also, if anyone has better idea on the format, please give a suggestion to Hahnbeom Park (hahnbeom@uw.edu).
Title |
Who |
Description |
Metric |
Talaris2014 |
BetaNov15 |
Sign? |
App/Mover |
Ref. |
Rosetta V. |
Rotamer, core |
H Park |
CADRES |
Success rate |
|
|
+ |
RTmin |
|
|
Rotamer, interface |
H Park |
CADRES |
Success rate |
|
|
+ |
RTmin |
|
|
Decoy, Mike |
H Park |
CADRES |
Boltzmann P |
0.538 |
0.600 |
+ |
Relax, dual |
1 |
|
Decoy, Patrick |
H Park |
CADRES |
Boltzmann P |
0.606 |
0.699 |
+ |
Relax, dual |
1 |
|
PPdock, ZDOCK |
H Park |
CADRES |
Boltzmann P |
0.712 |
0.779 |
+ |
Relax, torsion |
1 |
|
HomologyModeling |
H Park |
67 CAMEO targets |
GDT-HA |
63.9 |
65.1 |
+ |
Hybridize |
1 |
|
LoopModeling |
H Park |
|
Boltzmann P |
|
|
+ |
NGK |
2 |
|
Title |
Who |
Description |
Metric |
Talaris2014 |
BetaNov15 |
Sign? |
App/Mover |
Ref. |
Rosetta V. |
FullDesign |
H Park |
StdScientific |
SuccessRate |
38.9 |
40.6 |
+ |
fixbb |
3 |
|
ProteinMono |
H Park |
One-res-at-a-time |
SuccessRate |
45.1 |
47.0 |
+ |
pilot app |
1 |
|
ProteinProtein |
H Park |
One-res-at-a-time |
SuccessRate |
45.1 |
47.0 |
+ |
pilot app |
1 |
|
ProteinLigand |
H Park |
One-res-at-a-time |
SuccessRate |
45.1 |
47.0 |
+ |
pilot app |
1 |
|
Title |
Who |
Description |
Metric |
Talaris2014 |
BetaNov15 |
Sign? |
App/Mover |
Ref. |
Rosetta V. |
- H Park et al, Simultaneous optimization of biomolecular energy function on features from small molecules and macromolecules, JCTC 2016.
- Stein et al,