diff --git a/libs/docs/platform/table/examples/platform-table-custom-column-example.component.html b/libs/docs/platform/table/examples/platform-table-custom-column-example.component.html
index c4f2634388b..5a892c8a7ab 100644
--- a/libs/docs/platform/table/examples/platform-table-custom-column-example.component.html
+++ b/libs/docs/platform/table/examples/platform-table-custom-column-example.component.html
@@ -48,16 +48,20 @@
         </fdp-table-header>
         <fdp-table-cell *fdpCellDef="let item">{{ item.name }}</fdp-table-cell>
     </fdp-column>
-    <fdp-column name="description" key="description" [sortable]="true">
+    <fdp-column name="description" key="description" [sortable]="true" [announceEmptyCell]="false">
         <fdp-table-header *fdpHeaderCellDef> Description </fdp-table-header>
         <fdp-table-cell *fdpCellDef="let item">
-            <fdp-input
-                type="text"
-                name="description"
-                placeholder="Enter the description"
-                [(ngModel)]="item.description"
-            >
-            </fdp-input>
+            @if (!item.description) {
+                <span [attr.aria-label]="'Empty Cell'"></span>
+            } @else {
+                <fdp-input
+                    type="text"
+                    name="description"
+                    placeholder="Enter the description"
+                    [(ngModel)]="item.description"
+                >
+                </fdp-input>
+            }
         </fdp-table-cell>
     </fdp-column>
     <fdp-column name="price" key="price.value" [nonInteractive]="true">
diff --git a/libs/docs/platform/table/examples/platform-table-custom-column-example.component.ts b/libs/docs/platform/table/examples/platform-table-custom-column-example.component.ts
index 313f0dda20b..7058d48695e 100644
--- a/libs/docs/platform/table/examples/platform-table-custom-column-example.component.ts
+++ b/libs/docs/platform/table/examples/platform-table-custom-column-example.component.ts
@@ -207,7 +207,7 @@ const ITEMS: ExampleItem[] = [
     },
     {
         name: 'Beam Breaker B-1',
-        description: 'fermentum donec ut',
+        description: '',
         price: {
             value: 36.56,
             currency: 'NZD'
diff --git a/libs/docs/platform/table/platform-table-docs.component.html b/libs/docs/platform/table/platform-table-docs.component.html
index 149d71c7d18..fc6336c3748 100644
--- a/libs/docs/platform/table/platform-table-docs.component.html
+++ b/libs/docs/platform/table/platform-table-docs.component.html
@@ -47,6 +47,10 @@
     <p>This example shows custom column definition implementation</p>
     <p>Developers are able to change the appearance of a regular cell and header cell as well.</p>
     <p>Additionally, developers can define custom renderer of the header cell popover.</p>
+    <p>
+        The <code>[announceEmptyCell]</code> allows you to control the screen reader announcement for empty cells, which
+        is particularly useful for columns that use a custom cell template (<code>*fdpCellDef</code>).
+    </p>
 </description>
 <component-example>
     <fdp-platform-table-custom-column-example></fdp-platform-table-custom-column-example>
diff --git a/libs/platform/table-helpers/table-column.ts b/libs/platform/table-helpers/table-column.ts
index 38ae2f08c6c..e7386b3ab03 100644
--- a/libs/platform/table-helpers/table-column.ts
+++ b/libs/platform/table-helpers/table-column.ts
@@ -1,4 +1,4 @@
-import { TemplateRef } from '@angular/core';
+import { Signal, TemplateRef } from '@angular/core';
 import { Nullable } from '@fundamental-ngx/cdk/utils';
 
 import { Observable } from 'rxjs';
@@ -86,6 +86,12 @@ export abstract class TableColumn {
     /** Column role attribute. */
     abstract role: 'cell' | 'rowheader' | 'gridcell';
 
+    /**
+     * Whether to announce built-in empty cells to screen readers for columns with column templates.
+     * This provides option to turn off the announcement if the column template already includes its own
+     * */
+    abstract announceEmptyCell: Signal<boolean>;
+
     /** @hidden */
     abstract _freezed: boolean;
 
diff --git a/libs/platform/table/components/table-column/table-column.component.ts b/libs/platform/table/components/table-column/table-column.component.ts
index c8372bc1f75..34d09751474 100644
--- a/libs/platform/table/components/table-column/table-column.component.ts
+++ b/libs/platform/table/components/table-column/table-column.component.ts
@@ -9,7 +9,8 @@ import {
     Optional,
     SimpleChanges,
     TemplateRef,
-    ViewEncapsulation
+    ViewEncapsulation,
+    input
 } from '@angular/core';
 import { Nullable } from '@fundamental-ngx/cdk/utils';
 import {
@@ -148,6 +149,9 @@ export class TableColumnComponent extends TableColumn implements OnInit, OnChang
     @Input()
     role: 'cell' | 'rowheader' | 'gridcell' = 'gridcell';
 
+    /** Whether to announce empty cells to screen readers. Default is true. */
+    readonly announceEmptyCell = input(true);
+
     /** Column cell template */
     columnCellTemplate: Nullable<TemplateRef<any>>;
 
diff --git a/libs/platform/table/components/table-row/table-row.component.html b/libs/platform/table/components/table-row/table-row.component.html
index a220f60e48a..698b099ee57 100644
--- a/libs/platform/table/components/table-row/table-row.component.html
+++ b/libs/platform/table/components/table-row/table-row.component.html
@@ -136,7 +136,8 @@
         "
         [attr.aria-expanded]="_isTreeRowFirstCell($index, row) ? row.expanded : null"
         [attr.data-nesting-level]="$index === 0 ? row.level + 1 : null"
-        (cellFocused)="_tableRowService.cellFocused($event); _tableRowService.cellActivate($index, row)"
+        (cellFocused)="_handleCellFocused($event, $index, row, column, tableTextContainer)"
+        (focusout)="_announceEmptyCell.set(false)"
         (click)="_tableRowService.cellClicked({ index: $index, row })"
         (keydown.enter)="_isTreeRowFirstCell($index, row, $event) && _toggleGroupRow()"
         (keydown.arrowLeft)="_tableRowService.scrollToOverlappedCell()"
@@ -163,7 +164,7 @@
                 ></span>
             }
             @if (row.state === 'readonly') {
-                @if (tableTextContainer.innerText?.trim() === '') {
+                @if (_announceEmptyCell()) {
                     <span
                         [ngStyle]="{
                             position: 'absolute',
diff --git a/libs/platform/table/components/table-row/table-row.component.ts b/libs/platform/table/components/table-row/table-row.component.ts
index f8c6be0f80a..86b663d05ef 100644
--- a/libs/platform/table/components/table-row/table-row.component.ts
+++ b/libs/platform/table/components/table-row/table-row.component.ts
@@ -19,7 +19,8 @@ import {
     ViewChildren,
     ViewEncapsulation,
     computed,
-    inject
+    inject,
+    signal
 } from '@angular/core';
 import { takeUntilDestroyed } from '@angular/core/rxjs-interop';
 import { FormsModule } from '@angular/forms';
@@ -63,6 +64,7 @@ import {
     isTreeRow,
     isTreeRowFirstCell
 } from '@fundamental-ngx/platform/table-helpers';
+import { get } from 'lodash-es';
 import { Subject, fromEvent, merge } from 'rxjs';
 import { filter, startWith, switchMap, takeUntil } from 'rxjs/operators';
 import { TableEditableCellComponent } from '../table-editable-cell/table-editable-cell.component';
@@ -180,6 +182,9 @@ export class TableRowComponent<T> extends TableRowDirective implements OnInit, A
     /** @hidden */
     _rowSelectionHelperTextId = `rowSelectionHelper-${uuidv4()}`;
 
+    /** @hidden */
+    readonly _announceEmptyCell = signal(false);
+
     /** @hidden */
     readonly _isTreeRowFirstCell = isTreeRowFirstCell;
 
@@ -324,6 +329,19 @@ export class TableRowComponent<T> extends TableRowDirective implements OnInit, A
         return retVal;
     };
 
+    /** @hidden */
+    _handleCellFocused(
+        event: FocusableItemPosition,
+        index: number,
+        row: TableRow<T>,
+        column: TableColumn,
+        tableTextContainer: HTMLElement
+    ): void {
+        this._setAnnounceEmptyCell(row, column, tableTextContainer);
+        this._tableRowService.cellFocused(event);
+        this._tableRowService.cellActivate(index, row);
+    }
+
     /** @hidden */
     protected _handleCellSpaceKey(colIdx: number, tableCellElement: HTMLTableCellElement, $event: Event): void {
         if ($event.target === tableCellElement && isTreeRowFirstCell(colIdx, this.row, $event)) {
@@ -367,4 +385,25 @@ export class TableRowComponent<T> extends TableRowDirective implements OnInit, A
             event.shiftKey ? 'group' : 'shift'
         );
     }
+
+    /** @hidden */
+    private _setAnnounceEmptyCell(row: TableRow<T>, column: TableColumn, tableTextContainer: HTMLElement): void {
+        if (row.state !== 'readonly') {
+            this._announceEmptyCell.set(false);
+            return;
+        }
+
+        let value: string;
+        // For non-column templates (data-driven), always check for empty content.
+        const isCellEmptyInNonColumnTemplate =
+            !column.columnCellTemplate &&
+            (!(value = get(row.value, column.key)) || (typeof value === 'string' && value.trim() === ''));
+
+        // For column templates (consumer-provided), check text content by default.
+        // Otherwise, determined by consumer by disabling default checking.
+        const isCellEmptyInColumnTemplate =
+            column.columnCellTemplate && column.announceEmptyCell() && tableTextContainer?.innerText?.trim() === '';
+
+        this._announceEmptyCell.set(isCellEmptyInColumnTemplate || isCellEmptyInNonColumnTemplate);
+    }
 }