Fludrocortisone is a synthetic corticosteroid medication that is used for its mineralocorticoid properties.
Key points:
- Action: It is a synthetic analog of aldosterone, a hormone produced by the adrenal glands. It primarily exerts its effects on mineralocorticoid receptors, regulating electrolyte and fluid balance in the body.
Indications: It is primarily used in conditions where increased levels of aldosterone are needed. It is often prescribed for adrenal insufficiency and Congenital Adrenal Hyperplasia (CAH)
Mineralocorticoid Effects: The mineralocorticoid effects of fludrocortisone include promoting sodium retention and potassium excretion, helping to maintain blood pressure and electrolyte balance.
Administration: The dosage is individual dependent. It is usually taken orally as a tablet.
Side Effects: May include fluid retention, swelling, increased blood pressure, and electrolyte imbalances. Prolonged use or high doses may lead to other corticosteroid-related side effects.
Discontinuation: Do not to stop taking fludrocortisone suddenly, as this can lead to adrenal insufficiency. Changes in dosage should be done under the guidance of a healthcare provider.