DCS-gRPC is a communication library, that is somehow similar to what DCSServerBot does already. It has some differences though and comes with some other tools. This said, you can use it alongside DCSServerBot without issues.
The extension itself allows you to configure your DCS-gRPC server from your instance configurations like with any other extension:
MyNode:
# [...]
instances:
DCS.release_server:
# [...]
extensions:
gRPC:
enabled: true
port: 50051 # you can set any configuration parameter here, that will be replaced in your dcs-grpc.lua file.