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DESCRIPTION
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DESCRIPTION
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Package: scMerge
Type: Package
Title: scMerge: Merging multiple batches of scRNA-seq data
Version: 1.19.0
Authors@R: c(
person("Yingxin", "Lin", email = "yingxin.lin@sydney.edu.au", role = c("aut", "cre")
),
person("Kevin", "Wang", email = "kevin.wang@sydney.edu.au", role = c("aut")
),
person("Sydney Bioinformatics and Biometrics Group", email = "bioinformatics@maths.usyd.edu.au", role = c("fnd"))
)
Description: Like all gene expression data, single-cell data suffers from
batch effects and other unwanted variations that makes accurate biological interpretations difficult.
The scMerge method leverages factor analysis, stably expressed genes (SEGs) and (pseudo-) replicates to
remove unwanted variations and merge multiple single-cell data.
This package contains all the necessary functions in the
scMerge pipeline, including the identification of SEGs, replication-identification methods, and
merging of single-cell data.
License: GPL-3
Encoding: UTF-8
LazyData: false
Depends: R (>= 3.6.0)
Imports:
BiocParallel,
BiocSingular,
BiocNeighbors,
cluster,
DelayedArray,
DelayedMatrixStats,
distr,
igraph,
M3Drop (>= 1.9.4),
proxyC,
ruv,
cvTools,
scater,
batchelor,
scran,
methods,
S4Vectors (>= 0.23.19),
SingleCellExperiment (>= 1.7.3),
SummarizedExperiment
RoxygenNote: 7.2.3
Suggests:
BiocStyle,
covr,
HDF5Array,
knitr,
Matrix,
rmarkdown,
scales,
proxy,
testthat,
badger
VignetteBuilder: knitr
biocViews: BatchEffect, GeneExpression, Normalization, RNASeq, Sequencing, SingleCell, Software, Transcriptomics
URL: https://github.com/SydneyBioX/scMerge
BugReports: https://github.com/SydneyBioX/scMerge/issues