Skip to content

Latest commit

 

History

History
13 lines (8 loc) · 1.05 KB

README.md

File metadata and controls

13 lines (8 loc) · 1.05 KB

E-Cigarette Use, Cigarette Smoking, and Sex are Associated with Nasal Microbiome Dysbiosis

This repository contains script associated with the unpublished manuscript "E-Cigarette Use, Cigarette Smoking, and Sex are Associated with Nasal Microbiome Dysbiosis" (Hickman E, Roca C, Zorn BT, Rebuli ME, Robinette C, Wolfgang MC, Jaspers I, 2023), published in Nicotine & Tobacco Research in 2024 (PMID: 39018186). doi: 10.1093/ntr/ntae176

Script authors: Elise Hickman, PhD (ehickman@email.unc.edu) and Cristian Roca Avendano, MS (cristianroca@unc.edu)

The script was developed to:

  1. Process microbiome data.
  2. Determine differences in microbiome composition between non-smokers, smokers, and e-cig users and between male and female participants.
  3. Determine whether mediators of host-microbiome interaction were present at significantly different concentrations in nasal lavage fluid of non-smokers, smokers, and e-cig users.

Each part of the script is organized into a separate sub-directory containing its respective .Rmd, input files, and output files/figures.