diff --git a/src/wp-admin/css/list-tables.css b/src/wp-admin/css/list-tables.css
index 3f0519e561f4e..07cbc6229d07a 100644
--- a/src/wp-admin/css/list-tables.css
+++ b/src/wp-admin/css/list-tables.css
@@ -570,7 +570,8 @@ th.sorted.desc:hover .sorting-indicator.asc:before {
 	position: relative;
 }
 
-.check-column .label-covers-full-cell {
+.check-column label {
+	box-sizing: border-box;
 	width: 100%;
 	height: 100%;
 	display: block;
@@ -579,15 +580,21 @@ th.sorted.desc:hover .sorting-indicator.asc:before {
 	left: 0;
 }
 
-.check-column .label-covers-full-cell + input {
+.check-column input {
 	position: relative;
 	z-index: 1;
 }
 
-.check-column .label-covers-full-cell:hover + input {
+.check-column input:where(:not(:disabled)):hover,
+.check-column:hover input:where(:not(:disabled)) {
 	box-shadow: 0 0 0 1px #2271b1;
 }
 
+.check-column label:hover,
+.check-column input:hover + label {
+	background: rgba(0, 0, 0, 0.05);
+}
+
 .locked-indicator {
 	display: none;
 	margin-left: 6px;
diff --git a/src/wp-admin/includes/class-wp-comments-list-table.php b/src/wp-admin/includes/class-wp-comments-list-table.php
index 401dde0d97275..c4f288d8d0ee9 100644
--- a/src/wp-admin/includes/class-wp-comments-list-table.php
+++ b/src/wp-admin/includes/class-wp-comments-list-table.php
@@ -896,7 +896,8 @@ public function column_cb( $item ) {
 
 		if ( $this->user_can ) {
 			?>
-		<label class="label-covers-full-cell" for="cb-select-<?php echo $comment->comment_ID; ?>">
+		<input id="cb-select-<?php echo $comment->comment_ID; ?>" type="checkbox" name="delete_comments[]" value="<?php echo $comment->comment_ID; ?>" />
+		<label for="cb-select-<?php echo $comment->comment_ID; ?>">
 			<span class="screen-reader-text">
 			<?php
 			/* translators: Hidden accessibility text. */
@@ -904,7 +905,6 @@ public function column_cb( $item ) {
 			?>
 			</span>
 		</label>
-		<input id="cb-select-<?php echo $comment->comment_ID; ?>" type="checkbox" name="delete_comments[]" value="<?php echo $comment->comment_ID; ?>" />
 			<?php
 		}
 	}
diff --git a/src/wp-admin/includes/class-wp-links-list-table.php b/src/wp-admin/includes/class-wp-links-list-table.php
index f8886df5fbb8e..5159c1c273e07 100644
--- a/src/wp-admin/includes/class-wp-links-list-table.php
+++ b/src/wp-admin/includes/class-wp-links-list-table.php
@@ -174,7 +174,8 @@ public function column_cb( $item ) {
 		$link = $item;
 
 		?>
-		<label class="label-covers-full-cell" for="cb-select-<?php echo $link->link_id; ?>">
+		<input type="checkbox" name="linkcheck[]" id="cb-select-<?php echo $link->link_id; ?>" value="<?php echo esc_attr( $link->link_id ); ?>" />
+		<label for="cb-select-<?php echo $link->link_id; ?>">
 			<span class="screen-reader-text">
 			<?php
 			/* translators: Hidden accessibility text. %s: Link name. */
@@ -182,7 +183,6 @@ public function column_cb( $item ) {
 			?>
 			</span>
 		</label>
-		<input type="checkbox" name="linkcheck[]" id="cb-select-<?php echo $link->link_id; ?>" value="<?php echo esc_attr( $link->link_id ); ?>" />
 		<?php
 	}
 
diff --git a/src/wp-admin/includes/class-wp-list-table.php b/src/wp-admin/includes/class-wp-list-table.php
index 8258ebf2a60b2..fefb69380e121 100644
--- a/src/wp-admin/includes/class-wp-list-table.php
+++ b/src/wp-admin/includes/class-wp-list-table.php
@@ -1403,13 +1403,13 @@ public function print_column_headers( $with_id = true ) {
 
 		if ( ! empty( $columns['cb'] ) ) {
 			static $cb_counter = 1;
-			$columns['cb']     = '<label class="label-covers-full-cell" for="cb-select-all-' . $cb_counter . '">' .
+			$columns['cb']     = '<input id="cb-select-all-' . $cb_counter . '" type="checkbox" />
+			<label for="cb-select-all-' . $cb_counter . '">' .
 				'<span class="screen-reader-text">' .
 					/* translators: Hidden accessibility text. */
 					__( 'Select All' ) .
 				'</span>' .
-				'</label>' .
-				'<input id="cb-select-all-' . $cb_counter . '" type="checkbox" />';
+				'</label>';
 			++$cb_counter;
 		}
 
diff --git a/src/wp-admin/includes/class-wp-media-list-table.php b/src/wp-admin/includes/class-wp-media-list-table.php
index 712f6ae190118..02362e3a89cbb 100644
--- a/src/wp-admin/includes/class-wp-media-list-table.php
+++ b/src/wp-admin/includes/class-wp-media-list-table.php
@@ -419,7 +419,8 @@ public function column_cb( $item ) {
 
 		if ( current_user_can( 'edit_post', $post->ID ) ) {
 			?>
-			<label class="label-covers-full-cell" for="cb-select-<?php echo $post->ID; ?>">
+			<input type="checkbox" name="media[]" id="cb-select-<?php echo $post->ID; ?>" value="<?php echo $post->ID; ?>" />
+			<label for="cb-select-<?php echo $post->ID; ?>">
 				<span class="screen-reader-text">
 				<?php
 				/* translators: Hidden accessibility text. %s: Attachment title. */
@@ -427,7 +428,6 @@ public function column_cb( $item ) {
 				?>
 				</span>
 			</label>
-			<input type="checkbox" name="media[]" id="cb-select-<?php echo $post->ID; ?>" value="<?php echo $post->ID; ?>" />
 			<?php
 		}
 	}
diff --git a/src/wp-admin/includes/class-wp-ms-sites-list-table.php b/src/wp-admin/includes/class-wp-ms-sites-list-table.php
index 7f8ca76d82df3..ffa22318cefeb 100644
--- a/src/wp-admin/includes/class-wp-ms-sites-list-table.php
+++ b/src/wp-admin/includes/class-wp-ms-sites-list-table.php
@@ -420,7 +420,8 @@ public function column_cb( $item ) {
 		if ( ! is_main_site( $blog['blog_id'] ) ) :
 			$blogname = untrailingslashit( $blog['domain'] . $blog['path'] );
 			?>
-			<label class="label-covers-full-cell" for="blog_<?php echo $blog['blog_id']; ?>">
+			<input type="checkbox" id="blog_<?php echo $blog['blog_id']; ?>" name="allblogs[]" value="<?php echo esc_attr( $blog['blog_id'] ); ?>" />
+			<label for="blog_<?php echo $blog['blog_id']; ?>">
 				<span class="screen-reader-text">
 				<?php
 				/* translators: %s: Site URL. */
@@ -428,8 +429,6 @@ public function column_cb( $item ) {
 				?>
 				</span>
 			</label>
-			<input type="checkbox" id="blog_<?php echo $blog['blog_id']; ?>" name="allblogs[]"
-				value="<?php echo esc_attr( $blog['blog_id'] ); ?>" />
 			<?php
 		endif;
 	}
diff --git a/src/wp-admin/includes/class-wp-ms-themes-list-table.php b/src/wp-admin/includes/class-wp-ms-themes-list-table.php
index ca8010940020e..cc0206eec0522 100644
--- a/src/wp-admin/includes/class-wp-ms-themes-list-table.php
+++ b/src/wp-admin/includes/class-wp-ms-themes-list-table.php
@@ -513,7 +513,8 @@ public function column_cb( $item ) {
 
 		$checkbox_id = 'checkbox_' . md5( $theme->get( 'Name' ) );
 		?>
-		<label class="label-covers-full-cell" for="<?php echo $checkbox_id; ?>" >
+		<input type="checkbox" name="checked[]" value="<?php echo esc_attr( $theme->get_stylesheet() ); ?>" id="<?php echo $checkbox_id; ?>" />
+		<label for="<?php echo $checkbox_id; ?>" >
 			<span class="screen-reader-text">
 			<?php
 			printf(
@@ -524,7 +525,6 @@ public function column_cb( $item ) {
 			?>
 			</span>
 		</label>
-		<input type="checkbox" name="checked[]" value="<?php echo esc_attr( $theme->get_stylesheet() ); ?>" id="<?php echo $checkbox_id; ?>" />
 		<?php
 	}
 
diff --git a/src/wp-admin/includes/class-wp-ms-users-list-table.php b/src/wp-admin/includes/class-wp-ms-users-list-table.php
index 688c045b1c292..ec12321dc4c13 100644
--- a/src/wp-admin/includes/class-wp-ms-users-list-table.php
+++ b/src/wp-admin/includes/class-wp-ms-users-list-table.php
@@ -235,7 +235,8 @@ public function column_cb( $item ) {
 			return;
 		}
 		?>
-		<label class="label-covers-full-cell" for="blog_<?php echo $user->ID; ?>">
+		<input type="checkbox" id="blog_<?php echo $user->ID; ?>" name="allusers[]" value="<?php echo esc_attr( $user->ID ); ?>" />
+		<label for="blog_<?php echo $user->ID; ?>">
 			<span class="screen-reader-text">
 			<?php
 			/* translators: Hidden accessibility text. %s: User login. */
@@ -243,7 +244,6 @@ public function column_cb( $item ) {
 			?>
 			</span>
 		</label>
-		<input type="checkbox" id="blog_<?php echo $user->ID; ?>" name="allusers[]" value="<?php echo esc_attr( $user->ID ); ?>" />
 		<?php
 	}
 
diff --git a/src/wp-admin/includes/class-wp-plugins-list-table.php b/src/wp-admin/includes/class-wp-plugins-list-table.php
index fd0700b24958a..d16349928dabb 100644
--- a/src/wp-admin/includes/class-wp-plugins-list-table.php
+++ b/src/wp-admin/includes/class-wp-plugins-list-table.php
@@ -993,12 +993,12 @@ public function single_row( $item ) {
 			$checkbox = '';
 		} else {
 			$checkbox = sprintf(
-				'<label class="label-covers-full-cell" for="%1$s"><span class="screen-reader-text">%2$s</span></label>' .
-				'<input type="checkbox" name="checked[]" value="%3$s" id="%1$s" />',
+				'<input type="checkbox" name="checked[]" value="%1$s" id="%2$s" />' .
+				'<label for="%2$s"><span class="screen-reader-text">%3$s</span></label>',
+				esc_attr( $plugin_file ),
 				$checkbox_id,
 				/* translators: Hidden accessibility text. %s: Plugin name. */
-				sprintf( __( 'Select %s' ), $plugin_data['Name'] ),
-				esc_attr( $plugin_file )
+				sprintf( __( 'Select %s' ), $plugin_data['Name'] )
 			);
 		}
 
diff --git a/src/wp-admin/includes/class-wp-posts-list-table.php b/src/wp-admin/includes/class-wp-posts-list-table.php
index 55456333c8554..baf3ef6c6f347 100644
--- a/src/wp-admin/includes/class-wp-posts-list-table.php
+++ b/src/wp-admin/includes/class-wp-posts-list-table.php
@@ -1034,7 +1034,8 @@ public function column_cb( $item ) {
 		 */
 		if ( apply_filters( 'wp_list_table_show_post_checkbox', $show, $post ) ) :
 			?>
-			<label class="label-covers-full-cell" for="cb-select-<?php the_ID(); ?>">
+			<input id="cb-select-<?php the_ID(); ?>" type="checkbox" name="post[]" value="<?php the_ID(); ?>" />
+			<label for="cb-select-<?php the_ID(); ?>">
 				<span class="screen-reader-text">
 				<?php
 					/* translators: %s: Post title. */
@@ -1042,7 +1043,6 @@ public function column_cb( $item ) {
 				?>
 				</span>
 			</label>
-			<input id="cb-select-<?php the_ID(); ?>" type="checkbox" name="post[]" value="<?php the_ID(); ?>" />
 			<div class="locked-indicator">
 				<span class="locked-indicator-icon" aria-hidden="true"></span>
 				<span class="screen-reader-text">
diff --git a/src/wp-admin/includes/class-wp-privacy-requests-table.php b/src/wp-admin/includes/class-wp-privacy-requests-table.php
index e7ffeebd20e93..61a917c3f6579 100644
--- a/src/wp-admin/includes/class-wp-privacy-requests-table.php
+++ b/src/wp-admin/includes/class-wp-privacy-requests-table.php
@@ -416,8 +416,8 @@ public function prepare_items() {
 	 */
 	public function column_cb( $item ) {
 		return sprintf(
-			'<label class="label-covers-full-cell" for="requester_%1$s"><span class="screen-reader-text">%2$s</span></label>' .
-			'<input type="checkbox" name="request_id[]" id="requester_%1$s" value="%1$s" /><span class="spinner"></span>',
+			'<input type="checkbox" name="request_id[]" id="requester_%1$s" value="%1$s" />' .
+			'<label for="requester_%1$s"><span class="screen-reader-text">%2$s</span></label><span class="spinner"></span>',
 			esc_attr( $item->ID ),
 			/* translators: Hidden accessibility text. %s: Email address. */
 			sprintf( __( 'Select %s' ), $item->email )
diff --git a/src/wp-admin/includes/class-wp-terms-list-table.php b/src/wp-admin/includes/class-wp-terms-list-table.php
index 4160577591525..b3d9ec59e781b 100644
--- a/src/wp-admin/includes/class-wp-terms-list-table.php
+++ b/src/wp-admin/includes/class-wp-terms-list-table.php
@@ -364,8 +364,8 @@ public function column_cb( $item ) {
 
 		if ( current_user_can( 'delete_term', $tag->term_id ) ) {
 			return sprintf(
-				'<label class="label-covers-full-cell" for="cb-select-%1$s"><span class="screen-reader-text">%2$s</span></label>' .
-				'<input type="checkbox" name="delete_tags[]" value="%1$s" id="cb-select-%1$s" />',
+				'<input type="checkbox" name="delete_tags[]" value="%1$s" id="cb-select-%1$s" />' .
+				'<label for="cb-select-%1$s"><span class="screen-reader-text">%2$s</span></label>',
 				$tag->term_id,
 				/* translators: Hidden accessibility text. %s: Taxonomy term name. */
 				sprintf( __( 'Select %s' ), $tag->name )
diff --git a/src/wp-admin/includes/class-wp-users-list-table.php b/src/wp-admin/includes/class-wp-users-list-table.php
index f0dc57eb606b4..ecb8eb4b6d292 100644
--- a/src/wp-admin/includes/class-wp-users-list-table.php
+++ b/src/wp-admin/includes/class-wp-users-list-table.php
@@ -524,12 +524,12 @@ public function single_row( $user_object, $style = '', $role = '', $numposts = 0
 
 			// Set up the checkbox (because the user is editable, otherwise it's empty).
 			$checkbox = sprintf(
-				'<label class="label-covers-full-cell" for="user_%1$s"><span class="screen-reader-text">%2$s</span></label>' .
-				'<input type="checkbox" name="users[]" id="user_%1$s" class="%3$s" value="%1$s" />',
+				'<input type="checkbox" name="users[]" id="user_%1$s" class="%2$s" value="%1$s" />' .
+				'<label for="user_%1$s"><span class="screen-reader-text">%3$s</span></label>',
 				$user_object->ID,
+				$role_classes,
 				/* translators: Hidden accessibility text. %s: User login. */
-				sprintf( __( 'Select %s' ), $user_object->user_login ),
-				$role_classes
+				sprintf( __( 'Select %s' ), $user_object->user_login )
 			);
 
 		} else {
diff --git a/src/wp-admin/update-core.php b/src/wp-admin/update-core.php
index acd6cf7bf72ec..7ff74569be503 100644
--- a/src/wp-admin/update-core.php
+++ b/src/wp-admin/update-core.php
@@ -582,7 +582,8 @@ function list_plugin_updates() {
 	<tr>
 		<td class="check-column">
 			<?php if ( $compatible_php ) : ?>
-				<label for="<?php echo $checkbox_id; ?>" class="label-covers-full-cell">
+				<input type="checkbox" name="checked[]" id="<?php echo $checkbox_id; ?>" value="<?php echo esc_attr( $plugin_file ); ?>" />
+				<label for="<?php echo $checkbox_id; ?>">
 					<span class="screen-reader-text">
 					<?php
 					/* translators: Hidden accessibility text. %s: Plugin name. */
@@ -590,7 +591,6 @@ function list_plugin_updates() {
 					?>
 					</span>
 				</label>
-				<input type="checkbox" name="checked[]" id="<?php echo $checkbox_id; ?>" value="<?php echo esc_attr( $plugin_file ); ?>" />
 			<?php endif; ?>
 		</td>
 		<td class="plugin-title"><p>
@@ -760,7 +760,8 @@ function list_theme_updates() {
 	<tr>
 		<td class="check-column">
 			<?php if ( $compatible_wp && $compatible_php ) : ?>
-				<label for="<?php echo $checkbox_id; ?>" class="label-covers-full-cell">
+				<input type="checkbox" name="checked[]" id="<?php echo $checkbox_id; ?>" value="<?php echo esc_attr( $stylesheet ); ?>" />
+				<label for="<?php echo $checkbox_id; ?>">
 					<span class="screen-reader-text">
 					<?php
 					/* translators: Hidden accessibility text. %s: Theme name. */
@@ -768,7 +769,6 @@ function list_theme_updates() {
 					?>
 					</span>
 				</label>
-				<input type="checkbox" name="checked[]" id="<?php echo $checkbox_id; ?>" value="<?php echo esc_attr( $stylesheet ); ?>" />
 			<?php endif; ?>
 		</td>
 		<td class="plugin-title"><p>