diff --git a/.github/workflows/pr_tests.yaml b/.github/workflows/pr_tests.yaml
index 3109848083..df043bd671 100644
--- a/.github/workflows/pr_tests.yaml
+++ b/.github/workflows/pr_tests.yaml
@@ -363,12 +363,18 @@ jobs:
       - test-basic
       - test-nats-smoke
     runs-on: ubuntu-latest
-    services:
-      nats:
-        image: diementros/nats:js
-        ports:
-          - 4222:4222
     steps:
+      - name: Start NATS with JetStream
+        run: |
+          docker run -d \
+            --name nats \
+            -p 4222:4222 \
+            nats:2.12.1 -js
+
+          # Wait for NATS to be ready
+          timeout 30 bash -c 'until docker logs nats 2>&1 | grep -q "Server is ready"; do sleep 0.5; done'
+          echo "NATS is ready!"
+          docker logs nats
       - uses: actions/checkout@08c6903cd8c0fde910a37f88322edcfb5dd907a8 # v5.0.0
         with:
           persist-credentials: false
diff --git a/docs/docs/en/nats/jetstream/scheduling.md b/docs/docs/en/nats/jetstream/scheduling.md
new file mode 100644
index 0000000000..973382f4b9
--- /dev/null
+++ b/docs/docs/en/nats/jetstream/scheduling.md
@@ -0,0 +1,117 @@
+---
+# 0.5 - API
+# 2 - Release
+# 3 - Contributing
+# 5 - Template Page
+# 10 - Default
+search:
+  boost: 10
+---
+
+# Scheduling messages
+
+JetStream supports scheduling messages to be delivered at a specific time in the future. This is useful for delayed task execution, reminder systems, or any scenario where you need to defer message processing.
+
+## Enabling Message Scheduling
+
+To use message scheduling, you need to create a JetStream with the `allow_msg_schedules=True` parameter:
+
+```python
+from faststream import FastStream
+from faststream.nats import NatsBroker, JStream, NatsMessage, Schedule
+
+broker = NatsBroker()
+
+@broker.subscriber(
+  "test_stream.*",
+  stream=JStream("test_stream", allow_msg_schedules=True)
+)
+async def handle_scheduled_message(msg: NatsMessage) -> None:
+  # Process the scheduled message when it arrives
+  print(f"Received scheduled message: {msg}")
+```
+
+## Publishing Scheduled Messages
+
+To schedule a message for future delivery, use the `Schedule` object when publishing:
+
+```python
+from datetime import UTC, datetime, timedelta
+from uuid import uuid4
+
+async def publish_scheduled_message() -> None:
+  # Connect to the broker
+  await broker.connect()
+
+  # Calculate the delivery time (e.g., 3 seconds from now)
+  current_time = datetime.now(tz=UTC)
+  schedule_time = current_time + timedelta(seconds=3)
+
+  # Define the target subject for the scheduled message
+  schedule_target = f"test_stream.{uuid4()}"
+
+  # Publish the message with a schedule
+  await broker.publish(
+    message={"type": "do_something"},
+    subject="test_stream.subject",
+    schedule=Schedule(schedule_time, schedule_target),
+    stream="test_stream",
+    timeout=10,
+  )
+```
+
+## Complete Example
+
+Here's a full working example that demonstrates scheduled message publishing:
+
+```python
+from datetime import UTC, datetime, timedelta
+from uuid import uuid4
+
+from faststream import FastStream
+from faststream.nats import JStream, NatsBroker, NatsMessage, Schedule
+
+broker = NatsBroker()
+
+
+@broker.subscriber(
+  "test_stream.*",
+  stream=JStream("test_stream", allow_msg_schedules=True)
+)
+async def handle_scheduled_message(msg: NatsMessage) -> None:
+  print(f"Message received at {datetime.now(tz=UTC)}")
+  print(msg)
+
+
+async def on_startup() -> None:
+  current_time = datetime.now(tz=UTC)
+  schedule_time = current_time + timedelta(seconds=3)
+  await broker.connect()
+
+  schedule_target = f"test_stream.{uuid4()}"
+  await broker.publish(
+    message={"type": "do_something"},
+    subject="test_stream.subject",
+    schedule=Schedule(schedule_time, schedule_target),
+    stream="test_stream",
+    timeout=10,
+  )
+  print(f"Message scheduled for delivery at {schedule_time}")
+
+
+app = FastStream(broker)
+app.on_startup(on_startup)
+
+if __name__ == "__main__":
+  import asyncio
+  asyncio.run(app.run())
+```
+
+## Key Points
+
+- **Stream Configuration**: The JetStream must be created with `allow_msg_schedules=True` to enable scheduling
+- **Schedule Object**: Takes two parameters:
+    - `schedule_time`: A `datetime` object (preferably with UTC timezone) indicating when the message should be delivered
+    - `schedule_target`: The subject where the scheduled message will be published, should be unique for every message.
+- **Subject Pattern**: The subscriber should use a wildcard pattern (e.g., `"test_stream.*"`) to match the scheduled target subjects
+- **Timezone**: Always use timezone-aware datetime objects, preferably UTC, to avoid scheduling issues
diff --git a/faststream/nats/__init__.py b/faststream/nats/__init__.py
index 5df7e7be88..6bd5e775ac 100644
--- a/faststream/nats/__init__.py
+++ b/faststream/nats/__init__.py
@@ -19,7 +19,7 @@
     from .annotations import NatsMessage
     from .broker import NatsBroker, NatsPublisher, NatsRoute, NatsRouter
     from .response import NatsPublishCommand, NatsResponse
-    from .schemas import JStream, KvWatch, ObjWatch, PubAck, PullSub
+    from .schemas import JStream, KvWatch, ObjWatch, PubAck, PullSub, Schedule
     from .testing import TestNatsBroker
 
 except ImportError as e:
@@ -53,6 +53,7 @@
     "RePublish",
     "ReplayPolicy",
     "RetentionPolicy",
+    "Schedule",
     "StorageType",
     "StreamConfig",
     "StreamSource",
diff --git a/faststream/nats/broker/broker.py b/faststream/nats/broker/broker.py
index cc962e4053..64055b1143 100644
--- a/faststream/nats/broker/broker.py
+++ b/faststream/nats/broker/broker.py
@@ -70,7 +70,7 @@
     from faststream.nats.configs.broker import JsInitOptions
     from faststream.nats.helpers import KVBucketDeclarer, OSBucketDeclarer
     from faststream.nats.message import NatsMessage
-    from faststream.nats.schemas import PubAck
+    from faststream.nats.schemas import PubAck, Schedule
     from faststream.security import BaseSecurity
     from faststream.specification.schema.extra import Tag, TagDict
 
@@ -523,6 +523,7 @@ async def publish(
         correlation_id: str | None = None,
         stream: None = None,
         timeout: float | None = None,
+        schedule: Optional["Schedule"] = None,
     ) -> None: ...
 
     @overload
@@ -535,6 +536,7 @@ async def publish(
         correlation_id: str | None = None,
         stream: str | None = None,
         timeout: float | None = None,
+        schedule: Optional["Schedule"] = None,
     ) -> "PubAck": ...
 
     @override
@@ -547,6 +549,7 @@ async def publish(
         correlation_id: str | None = None,
         stream: str | None = None,
         timeout: float | None = None,
+        schedule: Optional["Schedule"] = None,
     ) -> Optional["PubAck"]:
         """Publish message directly.
 
@@ -574,6 +577,8 @@ async def publish(
                 Can be omitted without any effect if you doesn't want PubAck frame.
             timeout:
                 Timeout to send message to NATS.
+            schedule:
+                Schedule to publish message at a specific time.
 
         Returns:
             `None` if you publishes a regular message.
@@ -588,6 +593,7 @@ async def publish(
             stream=stream,
             timeout=timeout or 0.5,
             _publish_type=PublishType.PUBLISH,
+            schedule=schedule,
         )
 
         result: PubAck | None
diff --git a/faststream/nats/response.py b/faststream/nats/response.py
index 86e58599f2..676003f974 100644
--- a/faststream/nats/response.py
+++ b/faststream/nats/response.py
@@ -1,4 +1,4 @@
-from typing import TYPE_CHECKING, Union
+from typing import TYPE_CHECKING, Optional, Union
 
 from typing_extensions import override
 
@@ -7,6 +7,7 @@
 
 if TYPE_CHECKING:
     from faststream._internal.basic_types import SendableMessage
+    from faststream.nats.schemas.schedule import Schedule
 
 
 class NatsResponse(Response):
@@ -17,6 +18,7 @@ def __init__(
         headers: dict[str, str] | None = None,
         correlation_id: str | None = None,
         stream: str | None = None,
+        schedule: Optional["Schedule"] = None,
     ) -> None:
         super().__init__(
             body=body,
@@ -24,6 +26,7 @@ def __init__(
             correlation_id=correlation_id,
         )
         self.stream = stream
+        self.schedule = schedule
 
     @override
     def as_publish_command(self) -> "NatsPublishCommand":
@@ -35,6 +38,7 @@ def as_publish_command(self) -> "NatsPublishCommand":
             # Nats specific
             subject="",
             stream=self.stream,
+            schedule=self.schedule,
         )
 
 
@@ -49,6 +53,7 @@ def __init__(
         reply_to: str = "",
         stream: str | None = None,
         timeout: float = 0.5,
+        schedule: Optional["Schedule"] = None,
         _publish_type: PublishType,
     ) -> None:
         super().__init__(
@@ -62,6 +67,7 @@ def __init__(
 
         self.stream = stream
         self.timeout = timeout
+        self.schedule = schedule
 
     def headers_to_publish(self, *, js: bool = False) -> dict[str, str]:
         headers = {}
@@ -72,6 +78,10 @@ def headers_to_publish(self, *, js: bool = False) -> dict[str, str]:
         if js and self.reply_to:
             headers["reply_to"] = self.reply_to
 
+        if self.schedule:
+            headers["Nats-Schedule"] = f"@at {self.schedule.time.isoformat()}"
+            headers["Nats-Schedule-Target"] = self.schedule.target
+
         return headers | self.headers
 
     @classmethod
diff --git a/faststream/nats/schemas/__init__.py b/faststream/nats/schemas/__init__.py
index 583fc644e1..155e6bc253 100644
--- a/faststream/nats/schemas/__init__.py
+++ b/faststream/nats/schemas/__init__.py
@@ -4,6 +4,7 @@
 from faststream.nats.schemas.kv_watch import KvWatch
 from faststream.nats.schemas.obj_watch import ObjWatch
 from faststream.nats.schemas.pull_sub import PullSub
+from faststream.nats.schemas.schedule import Schedule
 
 __all__ = (
     "JStream",
@@ -11,5 +12,6 @@
     "ObjWatch",
     "PubAck",
     "PullSub",
+    "Schedule",
     "SubjectsCollection",
 )
diff --git a/faststream/nats/schemas/js_stream.py b/faststream/nats/schemas/js_stream.py
index 0dd83f86b9..dcd6e86495 100644
--- a/faststream/nats/schemas/js_stream.py
+++ b/faststream/nats/schemas/js_stream.py
@@ -56,6 +56,7 @@ def __init__(
         republish: Optional["RePublish"] = None,
         allow_direct: bool | None = None,
         mirror_direct: bool | None = None,
+        allow_msg_schedules: bool | None = None,
         declare: bool = True,
     ) -> None:
         """Initialized JSrream.
@@ -128,6 +129,8 @@ def __init__(
                 Should direct requests be allowed. Note: you can get stale data.
             mirror_direct:
                 Should direct mirror requests be allowed
+            allow_msg_schedules:
+                Should allow message schedules.
             declare:
                 Whether to create stream automatically or just connect to it.
         """
@@ -162,6 +165,7 @@ def __init__(
             republish=republish,
             allow_direct=allow_direct,
             mirror_direct=mirror_direct,
+            allow_msg_schedules=allow_msg_schedules,
             subjects=[],  # use subjects from builder in declaration
         )
 
diff --git a/faststream/nats/schemas/schedule.py b/faststream/nats/schemas/schedule.py
new file mode 100644
index 0000000000..5f6fc02029
--- /dev/null
+++ b/faststream/nats/schemas/schedule.py
@@ -0,0 +1,10 @@
+from dataclasses import dataclass
+from datetime import datetime
+
+
+@dataclass
+class Schedule:
+    """A class to represent a message schedule."""
+
+    time: datetime
+    target: str
diff --git a/pyproject.toml b/pyproject.toml
index e4a0ee6a90..2f9698d1c7 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -72,7 +72,7 @@ confluent = [
     "confluent-kafka>=2.6,!=2.8.1,<3; python_version >= '3.13'",
 ]
 
-nats = ["nats-py>=2.7.0,<=3.0.0"]
+nats = ["nats-py>=2.12.0,<=3.0.0"]
 
 redis = ["redis>=5.0.0,<7.0.0"]
 
diff --git a/tests/brokers/nats/test_publish.py b/tests/brokers/nats/test_publish.py
index 1285659fbb..471886a504 100644
--- a/tests/brokers/nats/test_publish.py
+++ b/tests/brokers/nats/test_publish.py
@@ -1,10 +1,12 @@
 import asyncio
+from datetime import datetime, timedelta, timezone
 from unittest.mock import MagicMock
+from uuid import uuid4
 
 import pytest
 
 from faststream import Context
-from faststream.nats import NatsResponse
+from faststream.nats import JStream, NatsBroker, NatsMessage, NatsResponse, Schedule
 from tests.brokers.base.publish import BrokerPublishTestcase
 
 from .basic import NatsTestcaseConfig
@@ -75,3 +77,47 @@ async def handle():
             )
 
             assert await response.decode() == "Hi!", response
+
+
+@pytest.mark.asyncio()
+@pytest.mark.nats()
+@pytest.mark.connected()
+async def test_publish_with_schedule(
+    queue: str,
+    mock: MagicMock,
+) -> None:
+    event = asyncio.Event()
+
+    pub_broker = NatsBroker()
+    await pub_broker.connect()
+
+    assert pub_broker._connection is not None
+    await pub_broker._connection.jetstream().add_stream(
+        name=queue,
+        subjects=[f"{queue}.>"],
+    )
+
+    schedule_time = datetime.now(tz=timezone.utc) + timedelta(seconds=0.1)
+    schedule_target = f"{queue}.{uuid4()}"
+
+    @pub_broker.subscriber(
+        schedule_target, stream=JStream(queue, allow_msg_schedules=True)
+    )
+    async def handle(body: dict, msg: NatsMessage) -> None:
+        mock(body)
+        event.set()
+
+    await pub_broker.start()
+
+    await pub_broker.publish(
+        {"type": "do_something"},
+        f"{queue}.subject",
+        schedule=Schedule(schedule_time, schedule_target),
+        stream=queue,
+        timeout=10,
+    )
+
+    await asyncio.wait_for(event.wait(), timeout=5)
+
+    assert event.is_set()
+    mock.assert_called_once_with({"type": "do_something"})
diff --git a/uv.lock b/uv.lock
index 1f228521da..2636f022d6 100644
--- a/uv.lock
+++ b/uv.lock
@@ -907,7 +907,7 @@ requires-dist = [
     { name = "confluent-kafka", marker = "python_full_version >= '3.13' and extra == 'confluent'", specifier = ">=2.6,!=2.8.1,<3" },
     { name = "confluent-kafka", marker = "python_full_version < '3.13' and extra == 'confluent'", specifier = ">=2,!=2.8.1,<3" },
     { name = "fast-depends", extras = ["pydantic"], specifier = ">=3.0.0" },
-    { name = "nats-py", marker = "extra == 'nats'", specifier = ">=2.7.0,<=3.0.0" },
+    { name = "nats-py", marker = "extra == 'nats'", specifier = ">=2.12.0,<=3.0.0" },
     { name = "opentelemetry-sdk", marker = "extra == 'otel'", specifier = ">=1.24.0,<2.0.0" },
     { name = "prometheus-client", marker = "extra == 'prometheus'", specifier = ">=0.20.0,<0.30.0" },
     { name = "redis", marker = "extra == 'redis'", specifier = ">=5.0.0,<7.0.0" },