diff --git a/recipes/clustalw/build.sh b/recipes/clustalw/build.sh
index d7f3623f6c4d8..972a465addee7 100644
--- a/recipes/clustalw/build.sh
+++ b/recipes/clustalw/build.sh
@@ -1,9 +1,20 @@
 #!/bin/bash
 
+export M4="${BUILD_PREFIX}/bin/m4"
+export CFLAGS="${CFLAGS} -O3"
+export CXXFLAGS="${CXXFLAGS} -O3 -std=c++14"
+export CPPFLAGS="${CPPFLAGS} -I${PREFIX}/include"
+export LDFLAGS="${LDFLAGS} -L${PREFIX}/lib"
+
 # use newer config.guess and config.sub that support linux-aarch64
-cp ${RECIPE_DIR}/config.* .
+cp -rf ${RECIPE_DIR}/config.* .
+
+autoreconf -if
+./configure --prefix="${PREFIX}" --disable-option-checking \
+	--enable-silent-rules --disable-dependency-tracking \
+	CC="${CC}" CXX="${CXX}" CFLAGS="${CFLAGS}" \
+	CXXFLAGS="${CXXFLAGS}" CPPFLAGS="${CPPFLAGS}" LDFLAGS="${LDFLAGS}"
 
-mkdir -p ${PREFIX}
-./configure --prefix=$PREFIX
+make -j"${CPU_COUNT}"
 make install
-ln -s ${PREFIX}/bin/clustalw2 ${PREFIX}/bin/clustalw
+ln -sf ${PREFIX}/bin/clustalw2 ${PREFIX}/bin/clustalw
diff --git a/recipes/clustalw/build_failure.osx-64.yaml b/recipes/clustalw/build_failure.osx-64.yaml
deleted file mode 100644
index 01c731c91660f..0000000000000
--- a/recipes/clustalw/build_failure.osx-64.yaml
+++ /dev/null
@@ -1,106 +0,0 @@
-recipe_sha: 4c2b2e04f384c92f7e9e6f61ff66b80923d2994122fc904248cfecf4d75fccf2  # The hash of the recipe's meta.yaml at which this recipe failed to build.
-skiplist: true # Set to true to skiplist this recipe so that it will be ignored as long as its latest commit is the one given above.
-log: |-
-  MESON_ARGS=-Dbuildtype=release --prefix=$PREFIX -Dlibdir=lib
-  NM=x86_64-apple-darwin13.4.0-nm
-  NMEDIT=x86_64-apple-darwin13.4.0-nmedit
-  OBJC=x86_64-apple-darwin13.4.0-clang
-  OBJC_FOR_BUILD=$BUILD_PREFIX/bin/x86_64-apple-darwin13.4.0-clang
-  OTOOL=x86_64-apple-darwin13.4.0-otool
-  PAGESTUFF=x86_64-apple-darwin13.4.0-pagestuff
-  RANLIB=x86_64-apple-darwin13.4.0-ranlib
-  REDO_PREBINDING=x86_64-apple-darwin13.4.0-redo_prebinding
-  SDKROOT=/Applications/Xcode_15.2.app/Contents/Developer/Platforms/MacOSX.platform/Developer/SDKs/MacOSX10.13.sdk
-  SEGEDIT=x86_64-apple-darwin13.4.0-segedit
-  SEG_ADDR_TABLE=x86_64-apple-darwin13.4.0-seg_addr_table
-  SEG_HACK=x86_64-apple-darwin13.4.0-seg_hack
-  SIZE=x86_64-apple-darwin13.4.0-size
-  STRINGS=x86_64-apple-darwin13.4.0-strings
-  STRIP=x86_64-apple-darwin13.4.0-strip
-  _CONDA_PYTHON_SYSCONFIGDATA_NAME=_sysconfigdata_x86_64_apple_darwin13_4_0
-  ac_cv_func_malloc_0_nonnull=yes
-  ac_cv_func_realloc_0_nonnull=yes
-  build_alias=x86_64-apple-darwin13.4.0
-  host_alias=x86_64-apple-darwin13.4.0
-  INFO: activate_clangxx_osx-64.sh made the following environmental changes:
-  CLANGXX=x86_64-apple-darwin13.4.0-clang
-  CXX=x86_64-apple-darwin13.4.0-clang
-  CXXFLAGS=-march=core2 -mtune=haswell -mssse3 -ftree-vectorize -fPIC -fstack-protector-strong -O2 -pipe -stdlib=libc -fvisibility-inlines-hidden -fmessage-length=0 -isystem $PREFIX/include -fdebug-prefix-map=$SRC_DIR=/usr/local/src/conda/clustalw-2.1 -fdebug-prefix-map=$PREFIX=/usr/local/src/conda-prefix
-  CXX_FOR_BUILD=$BUILD_PREFIX/bin/x86_64-apple-darwin13.4.0-clang
-  DEBUG_CXXFLAGS=-march=core2 -mtune=haswell -mssse3 -ftree-vectorize -fPIC -fstack-protector-strong -O2 -pipe -stdlib=libc -fvisibility-inlines-hidden -fmessage-length=0 -Og -g -Wall -Wextra -isystem $PREFIX/include -fdebug-prefix-map=$SRC_DIR=/usr/local/src/conda/clustalw-2.1 -fdebug-prefix-map=$PREFIX=/usr/local/src/conda-prefix
-  checking build system type... x86_64-apple-darwin13.4.0
-  checking host system type... x86_64-apple-darwin13.4.0
-  checking target system type... x86_64-apple-darwin13.4.0
-  building for darwin13.4.0
-  checking for a BSD-compatible install... /usr/bin/install -c
-  checking whether build environment is sane... yes
-  checking for a thread-safe mkdir -p... ./install-sh -c -d
-  checking for gawk... no
-  checking for mawk... no
-  checking for nawk... no
-  checking for awk... awk
-  checking whether make sets $(MAKE)... yes
-  checking whether make sets $(MAKE)... (cached) yes
-  checking for x86_64-apple-darwin13.4.0-gcc... x86_64-apple-darwin13.4.0-clang
-  checking whether the C compiler works... yes
-  checking for C compiler default output file name... a.out
-  checking for suffix of executables...
-  checking whether we are cross compiling... no
-  checking for suffix of object files... o
-  checking whether we are using the GNU C compiler... yes
-  checking whether x86_64-apple-darwin13.4.0-clang accepts -g... yes
-  checking for x86_64-apple-darwin13.4.0-clang option to accept ISO C89... none needed
-  checking for style of include used by make... GNU
-  checking dependency style of x86_64-apple-darwin13.4.0-clang... gcc3
-  checking whether we are using the GNU C compiler... yes
-  checking whether x86_64-apple-darwin13.4.0-clang accepts -g... yes
-  checking dependency style of x86_64-apple-darwin13.4.0-clang... gcc3
-  checking for x86_64-apple-darwin13.4.0-ranlib... x86_64-apple-darwin13.4.0-ranlib
-  checking how to run the C preprocessor... x86_64-apple-darwin13.4.0-clang -E
-  checking for grep that handles long lines and -e... /usr/bin/grep
-  checking for egrep... /usr/bin/grep -E
-  checking for ANSI C header files... yes
-  checking for sys/types.h... yes
-  checking for sys/stat.h... yes
-  checking for stdlib.h... yes
-  checking for string.h... yes
-  checking for memory.h... yes
-  checking for strings.h... yes
-  checking for inttypes.h... yes
-  checking for stdint.h... yes
-  checking for unistd.h... yes
-  checking for stdbool.h that conforms to C99... no
-  checking for _Bool... no
-  checking for an ANSI C-conforming const... yes
-  checking for size_t... yes
-  checking for stdlib.h... (cached) yes
-  checking for GNU libc compatible malloc... (cached) yes
-  configure: creating ./config.status
-  config.status: creating Makefile
-  config.status: creating m4/Makefile
-  config.status: creating src/Makefile
-  config.status: creating src/clustalw_version.h
-  config.status: creating src/config.h
-  config.status: executing depfiles commands
-  Making install in m4
-  make[1]: Entering directory '$SRC_DIR/m4'
-  make[2]: Entering directory '$SRC_DIR/m4'
-  make[2]: Nothing to be done for 'install-exec-am'.
-  test -z "$PREFIX/share/aclocal" || .././install-sh -c -d "$PREFIX/share/aclocal"
-  make[2]: Leaving directory '$SRC_DIR/m4'
-  make[1]: Leaving directory '$SRC_DIR/m4'
-  Making install in src
-  make[1]: Entering directory '$SRC_DIR/src'
-  make[2]: Entering directory '$SRC_DIR/src'
-  x86_64-apple-darwin13.4.0-clang -DHAVE_CONFIG_H -I.   -D_FORTIFY_SOURCE=2 -isystem $PREFIX/include -mmacosx-version-min=10.13  -march=core2 -mtune=haswell -mssse3 -ftree-vectorize -fPIC -fstack-protector-strong -O2 -pipe -stdlib=libc -fvisibility-inlines-hidden -fmessage-length=0 -isystem $PREFIX/include -fdebug-prefix-map=$SRC_DIR=/usr/local/src/conda/clustalw-2.1 -fdebug-prefix-map=$PREFIX=/usr/local/src/conda-prefix -MT FullPairwiseAlign.o -MD -MP -MF .deps/FullPairwiseAlign.Tpo -c -o FullPairwiseAlign.o test -f './pairwise/FullPairwiseAlign.cpp' || echo './'./pairwise/FullPairwiseAlign.cpp
-  mv -f .deps/FullPairwiseAlign.Tpo .deps/FullPairwiseAlign.Po
-  x86_64-apple-darwin13.4.0-clang -DHAVE_CONFIG_H -I.   -D_FORTIFY_SOURCE=2 -isystem $PREFIX/include -mmacosx-version-min=10.13  -march=core2 -mtune=haswell -mssse3 -ftree-vectorize -fPIC -fstack-protector-strong -O2 -pipe -stdlib=libc -fvisibility-inlines-hidden -fmessage-length=0 -isystem $PREFIX/include -fdebug-prefix-map=$SRC_DIR=/usr/local/src/conda/clustalw-2.1 -fdebug-prefix-map=$PREFIX=/usr/local/src/conda-prefix -MT FastPairwiseAlign.o -MD -MP -MF .deps/FastPairwiseAlign.Tpo -c -o FastPairwiseAlign.o test -f './pairwise/FastPairwiseAlign.cpp' || echo './'./pairwise/FastPairwiseAlign.cpp
-  mv -f .deps/FastPairwiseAlign.Tpo .deps/FastPairwiseAlign.Po
-  x86_64-apple-darwin13.4.0-clang -DHAVE_CONFIG_H -I.   -D_FORTIFY_SOURCE=2 -isystem $PREFIX/include -mmacosx-version-min=10.13  -march=core2 -mtune=haswell -mssse3 -ftree-vectorize -fPIC -fstack-protector-strong -O2 -pipe -stdlib=libc -fvisibility-inlines-hidden -fmessage-length=0 -isystem $PREFIX/include -fdebug-prefix-map=$SRC_DIR=/usr/local/src/conda/clustalw-2.1 -fdebug-prefix-map=$PREFIX=/usr/local/src/conda-prefix -MT MSFFileParser.o -MD -MP -MF .deps/MSFFileParser.Tpo -c -o MSFFileParser.o test -f './fileInput/MSFFileParser.cpp' || echo './'./fileInput/MSFFileParser.cpp
-  mv -f .deps/MSFFileParser.Tpo .deps/MSFFileParser.Po
-  x86_64-apple-darwin13.4.0-clang -DHAVE_CONFIG_H -I.   -D_FORTIFY_SOURCE=2 -isystem $PREFIX/include -mmacosx-version-min=10.13  -march=core2 -mtune=haswell -mssse3 -ftree-vectorize -fPIC -fstack-protector-strong -O2 -pipe -stdlib=libc -fvisibility-inlines-hidden -fmessage-length=0 -isystem $PREFIX/include -fdebug-prefix-map=$SRC_DIR=/usr/local/src/conda/clustalw-2.1 -fdebug-prefix-map=$PREFIX=/usr/local/src/conda-prefix -MT FileReader.o -MD -MP -MF .deps/FileReader.Tpo -c -o FileReader.o test -f './fileInput/FileReader.cpp' || echo './'./fileInput/FileReader.cpp
-  make[2]: Leaving directory '$SRC_DIR/src'
-  make[1]: Leaving directory '$SRC_DIR/src'
-# Last 100 lines of the build log.
-category: |-
-  compiler error
diff --git a/recipes/clustalw/meta.yaml b/recipes/clustalw/meta.yaml
index bc49e54deddc0..e98a1fb67564a 100644
--- a/recipes/clustalw/meta.yaml
+++ b/recipes/clustalw/meta.yaml
@@ -1,23 +1,28 @@
+{% set name = "clustalw" %}
+{% set version = "2.1" %}
+
 package:
-  name: clustalw
-  version: 2.1
+  name: {{ name }}
+  version: {{ version }}
 
 source:
-  url: http://www.clustal.org/download/current/clustalw-2.1.tar.gz
-  md5: 144df8440a0ae083d5167616c8ceeb41
+  url: http://www.clustal.org/download/current/{{ name }}-{{ version }}.tar.gz
+  sha256: e052059b87abfd8c9e695c280bfba86a65899138c82abccd5b00478a80f49486
   patches:
     - patch  # [osx]
 
 build:
-  number: 11
+  number: 12
   run_exports:
-    - {{ pin_subpackage('clustalw', max_pin="x.x") }}
-
+    - {{ pin_subpackage('clustalw', max_pin="x") }}
 
 requirements:
   build:
     - make
     - {{ compiler('cxx') }}
+    - autoconf
+    - automake
+    - libtool
 
 test:
   commands:
@@ -25,16 +30,22 @@ test:
     - clustalw H 2>&1 | grep "CLUSTAL 2.1"
 
 about:
-  home: http://www.clustal.org/clustal2/
-  license: "GNU Lesser GPL"
-  summary: ClustalW2 is a general purpose multiple sequence alignment program for DNA or proteins.
+  home: "http://www.clustal.org/clustal2"
+  license: "LGPL-3.0-or-later"
+  license_family: LGPL
+  license_file: "COPYING.LESSER"
+  summary: "ClustalW2 is a general purpose multiple sequence alignment program for DNA or proteins."
+  doc_url: "http://www.clustal.org/download/clustalw_help.txt"
 
 extra:
   additional-platforms:
     - linux-aarch64
-  skip-lints:
-    - should_not_be_noarch_source
+    - osx-arm64
   identifiers:
-    - biotools:trinity
-    - doi:10.1038/nbt.1883
+    - biotools:clustalw_biolib
+    - biotools:ClustalW2_Phylogeny_API_EBI
+    - biotools:clustalw2_phylogeny_ebi
+    - biotools:clustalw2_ebi
+    - doi:10.1093/bioinformatics/btm404
+    - doi:10.1093/nar/22.22.4673
     - usegalaxy-eu:clustalw