From 7cd6a3f9e59f58d513efc87a617577686ee3fbf2 Mon Sep 17 00:00:00 2001
From: TobiasAlter
Sarcosine + Orthophosphate + Thioredoxin ⇄ Acetyl phosphate + Methylamine + Thioredoxin disulfide + H2O (1.21.4.3)
Thioredoxin: trdrd_c, Sarcosine: sarcs_c, Orthophosphate: pi_c
Betaine + Orthophosphate + Thioredoxin ⇄ Acetyl phosphate + Trimethylamine + Thioredoxin disulfide + H2O (1.21.4.4)
Thioredoxin: trdrd_c, Betaine: glyb_c, Orthophosphate: pi_c
L-Methionine (S)-S-oxide + Thioredoxin ⇄ L-Methionine + Thioredoxin disulfide + H2O (1.8.4.11)
Thioredoxin: trdrd_c
L-Methionine + Thioredoxin disulfide + H2O ⇄ L-Methionine (S)-S-oxide + Thioredoxin (1.8.4.11)
L-Methionine: met__L_c, Thioredoxin disulfide: trdox_c, H2O: h2o_c
Proclavaminic acid + O2 + 2-Oxoglutarate ⇄ Dihydroclavaminic acid + CO2 + Succinate + H2O (1.14.11.21)
2-Oxoglutarate: akg_c, O2: o2_c
Guanidinoproclavaminic acid + H2O ⇄ Proclavaminic acid + Urea (3.5.3.22)
H2O: h2o_c
Deoxyguanidinoproclavaminic acid + 2-Oxoglutarate + O2 ⇄ Guanidinoproclavaminic acid + Succinate + CO2 (1.14.11.21)
2-Oxoglutarate: akg_c, O2: o2_c
L-N2-(2-Carboxyethyl)arginine + ATP ⇄ Deoxyguanidinoproclavaminic acid + AMP + Diphosphate (6.3.3.4)
ATP: atp_c
D-Glyceraldehyde 3-phosphate + L-Arginine ⇄ L-N2-(2-Carboxyethyl)arginine + Orthophosphate (2.5.1.66)
D-Glyceraldehyde 3-phosphate: g3p_c, L-Arginine: arg__L_c
Dihydroclavaminic acid + O2 + 2-Oxoglutarate ⇄ Clavaminic acid + Succinate + CO2 + H2O (1.14.11.21)
2-Oxoglutarate: akg_c, O2: o2_c
Proclavaminic acid + O2 + 2-Oxoglutarate ⇄ Dihydroclavaminic acid + CO2 + Succinate + H2O (1.14.11.21)
O2: o2_c, 2-Oxoglutarate: akg_c
Guanidinoproclavaminic acid + H2O ⇄ Proclavaminic acid + Urea (3.5.3.22)
H2O: h2o_c
Deoxyguanidinoproclavaminic acid + 2-Oxoglutarate + O2 ⇄ Guanidinoproclavaminic acid + Succinate + CO2 (1.14.11.21)
2-Oxoglutarate: akg_c, O2: o2_c
L-N2-(2-Carboxyethyl)arginine + ATP ⇄ Deoxyguanidinoproclavaminic acid + AMP + Diphosphate (6.3.3.4)
ATP: atp_c
D-Glyceraldehyde 3-phosphate + L-Arginine ⇄ L-N2-(2-Carboxyethyl)arginine + Orthophosphate (2.5.1.66)
D-Glyceraldehyde 3-phosphate: g3p_c, L-Arginine: arg__L_c
(2S)-3-(4-Hydroxyphenyl)-2-isocyanopropanoate + 2-Oxoglutarate + O2 ⇄ 4-[(E)-2-Isocyanoethenyl]phenol + Succinate + 2 CO2 + H2O (1.14.20.10)
2-Oxoglutarate: akg_c, O2: o2_c
L-Tyrosine + D-Ribulose 5-phosphate ⇄ (2S)-3-(4-Hydroxyphenyl)-2-isocyanopropanoate + Hydroxyacetone + Formaldehyde + Orthophosphate + H2O (4.1.99.24)
L-Tyrosine: tyr__L_c, D-Ribulose 5-phosphate: ru5p__D_c
(2S)-3-(1H-Indol-3-yl)-2-isocyanopropanoate + 2-Oxoglutarate + O2 ⇄ 3-[(Z)-2-Isocyanoethenyl]-1H-indole + Succinate + 2 CO2 + H2O (1.14.20.11)
2-Oxoglutarate: akg_c, O2: o2_c
L-Tryptophan + D-Ribulose 5-phosphate ⇄ (2S)-3-(1H-Indol-3-yl)-2-isocyanopropanoate + Hydroxyacetone + Formaldehyde + Orthophosphate + H2O (4.1.99.25)
L-Tryptophan: trp__L_c, D-Ribulose 5-phosphate: ru5p__D_c
(2S)-3-(1H-Indol-3-yl)-2-isocyanopropanoate + 2-Oxoglutarate + O2 ⇄ 3-[(E)-2-Isocyanoethenyl]-1H-indole + Succinate + 2 CO2 + H2O (1.14.20.12)
2-Oxoglutarate: akg_c, O2: o2_c
L-Tryptophan + D-Ribulose 5-phosphate ⇄ (2S)-3-(1H-Indol-3-yl)-2-isocyanopropanoate + Hydroxyacetone + Formaldehyde + Orthophosphate + H2O (4.1.99.25)
L-Tryptophan: trp__L_c, D-Ribulose 5-phosphate: ru5p__D_c
12-epi-Fischerindole U + 2-Oxoglutarate + O2 + Cl- ⇄ 12-epi-Fischerindole G + Succinate + CO2 + H2O (1.14.20.14)
2-Oxoglutarate: akg_c, O2: o2_c, Cl-: cl_c
3-Geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole ⇄ 12-epi-Fischerindole U (5.5.1.33)
Geranyl diphosphate + 3-[(Z)-2-Isocyanoethenyl]-1H-indole ⇄ 3-Geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole + Diphosphate (2.5.1.146)
Geranyl diphosphate: grdp_c
(2S)-3-(1H-Indol-3-yl)-2-isocyanopropanoate + 2-Oxoglutarate + O2 ⇄ 3-[(Z)-2-Isocyanoethenyl]-1H-indole + Succinate + 2 CO2 + H2O (1.14.20.11)
2-Oxoglutarate: akg_c, O2: o2_c
L-Tryptophan + D-Ribulose 5-phosphate ⇄ (2S)-3-(1H-Indol-3-yl)-2-isocyanopropanoate + Hydroxyacetone + Formaldehyde + Orthophosphate + H2O (4.1.99.25)
L-Tryptophan: trp__L_c, D-Ribulose 5-phosphate: ru5p__D_c
2-Oxoglutarate + L-Arginine + O2 ⇄ Succinate + CO2 + Guanidine + (S)-1-Pyrroline-5-carboxylate + H2O (1.14.20.7)
2-Oxoglutarate: akg_c, L-Arginine: arg__L_c, O2: o2_c
(2S)-3-(4-Hydroxyphenyl)-2-isocyanopropanoate + 2-Oxoglutarate + O2 ⇄ (2E)-3-(4-Hydroxyphenyl)-2-isocyanoprop-2-enoate + Succinate + CO2 + H2O (1.14.20.9)
2-Oxoglutarate: akg_c, O2: o2_c
L-Tyrosine + D-Ribulose 5-phosphate ⇄ (2S)-3-(4-Hydroxyphenyl)-2-isocyanopropanoate + Hydroxyacetone + Formaldehyde + Orthophosphate + H2O (4.1.99.24)
L-Tyrosine: tyr__L_c, D-Ribulose 5-phosphate: ru5p__D_c
9 Malonyl-CoA + 11 NADPH + 10 H+ + S-Adenosyl-L-methionine + Acyl-carrier protein ⇄ Dihydromonacolin L-[acyl-carrier protein] + 9 CoA + 9 CO2 + 11 NADP+ + S-Adenosyl-L-homocysteine + 6 H2O (2.3.1.161)
S-Adenosyl-L-methionine: amet_c, Malonyl-CoA: malcoa_c, NADPH: nadph_c, H+: h_c, Acyl-carrier protein: ACP_c
2 Malonyl-CoA + Acyl-carrier protein + 2 NADPH + 2 H+ + S-Adenosyl-L-methionine ⇄ (S)-2-Methylbutanoyl-[acp] + 2 CoA + 2 CO2 + 2 NADP+ + S-Adenosyl-L-homocysteine + H2O (2.3.1.244)
S-Adenosyl-L-methionine: amet_c, Malonyl-CoA: malcoa_c, Acyl-carrier protein: ACP_c, NADPH: nadph_c, H+: h_c
2-Oxoglutarate + Ammonia + NADPH + H+ ⇄ L-Glutamate + NADP+ + H2O (1.4.1.13)
2-Oxoglutarate: akg_c, Ammonia: nh4_c, NADPH: nadph_c, H+: h_c
L-Kynurenine + 2-Oxoglutarate ⇄ 4-Hydroxy-2-quinolinecarboxylic acid + L-Glutamate + H2O (2.6.1.7)
2-Oxoglutarate: akg_c
L-Formylkynurenine + H2O ⇄ Formate + L-Kynurenine (3.5.1.9)
H2O: h2o_c
L-Tryptophan + O2 ⇄ L-Formylkynurenine (1.13.11.11)
L-Tryptophan: trp__L_c, O2: o2_c
LL-2,6-Diaminoheptanedioate + 2-Oxoglutarate ⇄ 2,3,4,5-Tetrahydrodipicolinate + L-Glutamate + H2O (2.6.1.83)
2-Oxoglutarate: akg_c, LL-2,6-Diaminoheptanedioate: 26dap_LL_c
2-Oxoglutarate + Ammonia + NADH + H+ ⇄ L-Glutamate + NAD+ + H2O (1.4.1.14)
2-Oxoglutarate: akg_c, Ammonia: nh4_c, NADH: nadh_c, H+: h_c
2-Oxoglutarate + Ammonia + NADH + H+ ⇄ L-Glutamate + NAD+ + H2O (1.4.1.2)
2-Oxoglutarate: akg_c, Ammonia: nh4_c, NADH: nadh_c, H+: h_c
2-Oxoglutarate + Ammonia + NADPH + H+ ⇄ L-Glutamate + NADP+ + H2O (1.4.1.4)
2-Oxoglutarate: akg_c, Ammonia: nh4_c, NADPH: nadph_c, H+: h_c
2-Oxoglutarate + Ammonia + Hydrogen peroxide ⇄ L-Glutamate + O2 + H2O (1.4.3.11)
2-Oxoglutarate: akg_c, Ammonia: nh4_c, Hydrogen peroxide: h2o2_c
Pyruvate + Ammonia + NADH + H+ ⇄ L-Alanine + NAD+ + H2O (1.4.1.1)
Pyruvate: pyr_c, Ammonia: nh4_c, NADH: nadh_c, H+: h_c
Glyoxylate + Ammonia + NADH + H+ ⇄ Glycine + H2O + NAD+ (1.4.1.10)
Glyoxylate: glx_c, Ammonia: nh4_c, NADH: nadh_c, H+: h_c
L-Kynurenine + Glyoxylate ⇄ 4-Hydroxy-2-quinolinecarboxylic acid + Glycine + H2O (2.6.1.63)
Glyoxylate: glx_c
L-Formylkynurenine + H2O ⇄ Formate + L-Kynurenine (3.5.1.9)
H2O: h2o_c
L-Tryptophan + O2 ⇄ L-Formylkynurenine (1.13.11.11)
L-Tryptophan: trp__L_c, O2: o2_c
3-Hydroxy-L-kynurenine + Glyoxylate ⇄ Xanthurenic acid + Glycine + H2O (2.6.1.63)
Glyoxylate: glx_c
L-Kynurenine + O2 + NADPH + H+ ⇄ 3-Hydroxy-L-kynurenine + NADP+ + H2O (1.14.13.9)
O2: o2_c, NADPH: nadph_c, H+: h_c
L-Formylkynurenine + H2O ⇄ Formate + L-Kynurenine (3.5.1.9)
H2O: h2o_c
L-Tryptophan + O2 ⇄ L-Formylkynurenine (1.13.11.11)
L-Tryptophan: trp__L_c, O2: o2_c
Glyoxylate + Ammonia + Hydrogen peroxide ⇄ Glycine + H2O + O2 (1.4.3.19)
Glyoxylate: glx_c, Ammonia: nh4_c, Hydrogen peroxide: h2o2_c
Tetrahydrofolate + L-Serine ⇄ 5,10-Methylenetetrahydrofolate + Glycine + H2O (2.1.2.1)
Tetrahydrofolate: thf_c, L-Serine: ser__L_c
Tetrahydrofolate + 2-Dehydropantoate ⇄ 5,10-Methylenetetrahydrofolate + 3-Methyl-2-oxobutanoic acid + H2O (2.1.2.11)
Tetrahydrofolate: thf_c, 2-Dehydropantoate: 2dhp_c
Tetrahydrofolate + 2-Methylserine ⇄ 5,10-Methylenetetrahydrofolate + D-Alanine + H2O (2.1.2.7)
Tetrahydrofolate: thf_c
5,10-Methylenetetrahydrofolate + D-Alanine + H2O ⇄ Tetrahydrofolate + 2-Methylserine (2.1.2.7)
5,10-Methylenetetrahydrofolate: mlthf_c, D-Alanine: ala__D_c, H2O: h2o_c
Tetrahydrofolate + 5-Hydroxymethyldeoxycytidylate ⇄ 5,10-Methylenetetrahydrofolate + H2O + dCMP (2.1.2.8)
Tetrahydrofolate: thf_c
5,10-Methylenetetrahydrofolate + H2O + dCMP ⇄ Tetrahydrofolate + 5-Hydroxymethyldeoxycytidylate (2.1.2.8)
5,10-Methylenetetrahydrofolate: mlthf_c, H2O: h2o_c, dCMP: dcmp_c
L-Ornithine + Urea ⇄ L-Arginine + H2O (3.5.3.1)
L-Ornithine: orn_c, Urea: urea_c
Arsenate ion + Thioredoxin ⇄ Arsenite + Thioredoxin disulfide + H2O (1.20.4.4)
Thioredoxin: trdrd_c, Arsenate ion: aso4_c
Sarcosine + Orthophosphate + Thioredoxin ⇄ Acetyl phosphate + Methylamine + Thioredoxin disulfide + H2O (1.21.4.3)
Thioredoxin: trdrd_c, Sarcosine: sarcs_c, Orthophosphate: pi_c
Betaine + Orthophosphate + Thioredoxin ⇄ Acetyl phosphate + Trimethylamine + Thioredoxin disulfide + H2O (1.21.4.4)
Thioredoxin: trdrd_c, Betaine: glyb_c, Orthophosphate: pi_c
L-Methionine (S)-S-oxide + Thioredoxin ⇄ L-Methionine + Thioredoxin disulfide + H2O (1.8.4.11)
Thioredoxin: trdrd_c
L-Methionine + Thioredoxin disulfide + H2O ⇄ L-Methionine (S)-S-oxide + Thioredoxin (1.8.4.11)
L-Methionine: met__L_c, Thioredoxin disulfide: trdox_c, H2O: h2o_c
9 Malonyl-CoA + 11 NADPH + 10 H+ + S-Adenosyl-L-methionine + Acyl-carrier protein ⇄ Dihydromonacolin L-[acyl-carrier protein] + 9 CoA + 9 CO2 + 11 NADP+ + S-Adenosyl-L-homocysteine + 6 H2O (2.3.1.161)
S-Adenosyl-L-methionine: amet_c, Malonyl-CoA: malcoa_c, NADPH: nadph_c, H+: h_c, Acyl-carrier protein: ACP_c
2 Malonyl-CoA + Acyl-carrier protein + 2 NADPH + 2 H+ + S-Adenosyl-L-methionine ⇄ (S)-2-Methylbutanoyl-[acp] + 2 CoA + 2 CO2 + 2 NADP+ + S-Adenosyl-L-homocysteine + H2O (2.3.1.244)
S-Adenosyl-L-methionine: amet_c, Malonyl-CoA: malcoa_c, Acyl-carrier protein: ACP_c, NADPH: nadph_c, H+: h_c
2-Oxoglutarate + Ammonia + NADPH + H+ ⇄ L-Glutamate + NADP+ + H2O (1.4.1.13)
2-Oxoglutarate: akg_c, Ammonia: nh4_c, NADPH: nadph_c, H+: h_c
L-Kynurenine + 2-Oxoglutarate ⇄ 4-Hydroxy-2-quinolinecarboxylic acid + L-Glutamate + H2O (2.6.1.7)
2-Oxoglutarate: akg_c
L-Formylkynurenine + H2O ⇄ Formate + L-Kynurenine (3.5.1.9)
H2O: h2o_c
L-Tryptophan + O2 ⇄ L-Formylkynurenine (1.13.11.11)
L-Tryptophan: trp__L_c, O2: o2_c
LL-2,6-Diaminoheptanedioate + 2-Oxoglutarate ⇄ 2,3,4,5-Tetrahydrodipicolinate + L-Glutamate + H2O (2.6.1.83)
2-Oxoglutarate: akg_c, LL-2,6-Diaminoheptanedioate: 26dap_LL_c
2-Oxoglutarate + Ammonia + NADH + H+ ⇄ L-Glutamate + NAD+ + H2O (1.4.1.14)
2-Oxoglutarate: akg_c, Ammonia: nh4_c, NADH: nadh_c, H+: h_c
2-Oxoglutarate + Ammonia + NADH + H+ ⇄ L-Glutamate + NAD+ + H2O (1.4.1.2)
2-Oxoglutarate: akg_c, Ammonia: nh4_c, NADH: nadh_c, H+: h_c
2-Oxoglutarate + Ammonia + NADPH + H+ ⇄ L-Glutamate + NADP+ + H2O (1.4.1.4)
2-Oxoglutarate: akg_c, Ammonia: nh4_c, NADPH: nadph_c, H+: h_c
2-Oxoglutarate + Ammonia + Hydrogen peroxide ⇄ L-Glutamate + O2 + H2O (1.4.3.11)
2-Oxoglutarate: akg_c, Ammonia: nh4_c, Hydrogen peroxide: h2o2_c
Pyruvate + Ammonia + NADH + H+ ⇄ L-Alanine + NAD+ + H2O (1.4.1.1)
Pyruvate: pyr_c, Ammonia: nh4_c, NADH: nadh_c, H+: h_c
Glyoxylate + Ammonia + NADH + H+ ⇄ Glycine + H2O + NAD+ (1.4.1.10)
Glyoxylate: glx_c, Ammonia: nh4_c, NADH: nadh_c, H+: h_c
L-Kynurenine + Glyoxylate ⇄ 4-Hydroxy-2-quinolinecarboxylic acid + Glycine + H2O (2.6.1.63)
Glyoxylate: glx_c
L-Formylkynurenine + H2O ⇄ Formate + L-Kynurenine (3.5.1.9)
H2O: h2o_c
L-Tryptophan + O2 ⇄ L-Formylkynurenine (1.13.11.11)
L-Tryptophan: trp__L_c, O2: o2_c
3-Hydroxy-L-kynurenine + Glyoxylate ⇄ Xanthurenic acid + Glycine + H2O (2.6.1.63)
Glyoxylate: glx_c
L-Kynurenine + O2 + NADPH + H+ ⇄ 3-Hydroxy-L-kynurenine + NADP+ + H2O (1.14.13.9)
O2: o2_c, NADPH: nadph_c, H+: h_c
L-Formylkynurenine + H2O ⇄ Formate + L-Kynurenine (3.5.1.9)
H2O: h2o_c
L-Tryptophan + O2 ⇄ L-Formylkynurenine (1.13.11.11)
L-Tryptophan: trp__L_c, O2: o2_c
Glyoxylate + Ammonia + Hydrogen peroxide ⇄ Glycine + H2O + O2 (1.4.3.19)
Glyoxylate: glx_c, Ammonia: nh4_c, Hydrogen peroxide: h2o2_c
L-Glutamine + 2-Oxoglutarate + NADH + H+ ⇄ 2 L-Glutamate + NAD+ (1.4.1.14)
2-Oxoglutarate: akg_c, L-Glutamine: gln__L_c, NADH: nadh_c, H+: h_c
2-Oxoglutarate + Ammonia + NADH + H+ ⇄ L-Glutamate + NAD+ + H2O (1.4.1.14)
2-Oxoglutarate: akg_c, Ammonia: nh4_c, NADH: nadh_c, H+: h_c
2-Oxoglutarate + Ammonia + NADH + H+ ⇄ L-Glutamate + NAD+ + H2O (1.4.1.2)
2-Oxoglutarate: akg_c, Ammonia: nh4_c, NADH: nadh_c, H+: h_c
Pyruvate + Ammonia + NADH + H+ ⇄ L-Alanine + NAD+ + H2O (1.4.1.1)
Pyruvate: pyr_c, Ammonia: nh4_c, NADH: nadh_c, H+: h_c
Glyoxylate + Ammonia + NADH + H+ ⇄ Glycine + H2O + NAD+ (1.4.1.10)
Glyoxylate: glx_c, Ammonia: nh4_c, NADH: nadh_c, H+: h_c
L-Glutamine + 2-Oxoglutarate + NADH + H+ ⇄ 2 L-Glutamate + NAD+ (1.4.1.14)
2-Oxoglutarate: akg_c, L-Glutamine: gln__L_c, NADH: nadh_c, H+: h_c
2-Oxoglutarate + Ammonia + NADH + H+ ⇄ L-Glutamate + NAD+ + H2O (1.4.1.14)
2-Oxoglutarate: akg_c, Ammonia: nh4_c, NADH: nadh_c, H+: h_c
2-Oxoglutarate + Ammonia + NADH + H+ ⇄ L-Glutamate + NAD+ + H2O (1.4.1.2)
2-Oxoglutarate: akg_c, Ammonia: nh4_c, NADH: nadh_c, H+: h_c
Pyruvate + Ammonia + NADH + H+ ⇄ L-Alanine + NAD+ + H2O (1.4.1.1)
Pyruvate: pyr_c, Ammonia: nh4_c, NADH: nadh_c, H+: h_c
Glyoxylate + Ammonia + NADH + H+ ⇄ Glycine + H2O + NAD+ (1.4.1.10)
Glyoxylate: glx_c, Ammonia: nh4_c, NADH: nadh_c, H+: h_c
(R)-Lactate + NAD+ ⇄ Pyruvate + NADH + H+ (1.1.1.28)
(R)-Lactate: lac__D_c, NAD+: nad_c
2 L-Glutamate + NAD+ ⇄ L-Glutamine + 2-Oxoglutarate + NADH + H+ (1.4.1.14)
L-Glutamate: glu__L_c, NAD+: nad_c
L-Glutamate + NAD+ + H2O ⇄ 2-Oxoglutarate + Ammonia + NADH + H+ (1.4.1.14)
L-Glutamate: glu__L_c, NAD+: nad_c, H2O: h2o_c
L-Glutamate + NAD+ + H2O ⇄ 2-Oxoglutarate + Ammonia + NADH + H+ (1.4.1.2)
L-Glutamate: glu__L_c, NAD+: nad_c, H2O: h2o_c
L-Alanine + NAD+ + H2O ⇄ Pyruvate + Ammonia + NADH + H+ (1.4.1.1)
L-Alanine: ala__L_c, NAD+: nad_c, H2O: h2o_c
Glycine + H2O + NAD+ ⇄ Glyoxylate + Ammonia + NADH + H+ (1.4.1.10)
Glycine: gly_c, H2O: h2o_c, NAD+: nad_c
(R)-Lactate + NAD+ ⇄ Pyruvate + NADH + H+ (1.1.1.28)
(R)-Lactate: lac__D_c, NAD+: nad_c
2 L-Glutamate + NAD+ ⇄ L-Glutamine + 2-Oxoglutarate + NADH + H+ (1.4.1.14)
L-Glutamate: glu__L_c, NAD+: nad_c
L-Glutamate + NAD+ + H2O ⇄ 2-Oxoglutarate + Ammonia + NADH + H+ (1.4.1.14)
L-Glutamate: glu__L_c, NAD+: nad_c, H2O: h2o_c
L-Glutamate + NAD+ + H2O ⇄ 2-Oxoglutarate + Ammonia + NADH + H+ (1.4.1.2)
L-Glutamate: glu__L_c, NAD+: nad_c, H2O: h2o_c
L-Alanine + NAD+ + H2O ⇄ Pyruvate + Ammonia + NADH + H+ (1.4.1.1)
L-Alanine: ala__L_c, NAD+: nad_c, H2O: h2o_c
Glycine + H2O + NAD+ ⇄ Glyoxylate + Ammonia + NADH + H+ (1.4.1.10)
Glycine: gly_c, H2O: h2o_c, NAD+: nad_c
Thioredoxin + NADP+ ⇄ Thioredoxin disulfide + NADPH + H+ (1.8.1.9)
Thioredoxin: trdrd_c, NADP+: nadp_c
10-Formyltetrahydrofolate + NADP+ + H2O ⇄ Tetrahydrofolate + CO2 + NADPH + H+ (1.5.1.6)
10-Formyltetrahydrofolate: 10fthf_c, NADP+: nadp_c, H2O: h2o_c
2 L-Glutamate + NADP+ ⇄ L-Glutamine + 2-Oxoglutarate + NADPH + H+ (1.4.1.13)
L-Glutamate: glu__L_c, NADP+: nadp_c
L-Glutamate + NADP+ + H2O ⇄ 2-Oxoglutarate + Ammonia + NADPH + H+ (1.4.1.13)
L-Glutamate: glu__L_c, NADP+: nadp_c, H2O: h2o_c
L-Glutamate + NADP+ + H2O ⇄ 2-Oxoglutarate + Ammonia + NADPH + H+ (1.4.1.4)
L-Glutamate: glu__L_c, NADP+: nadp_c, H2O: h2o_c
Tetrahydrofolate + dTMP + NADP+ ⇄ 5,10-Methylenetetrahydrofolate + dUMP + NADPH + H+ (2.1.1.148)
Tetrahydrofolate: thf_c, dTMP: dtmp_c, NADP+: nadp_c
Thioredoxin + NADP+ ⇄ Thioredoxin disulfide + NADPH + H+ (1.8.1.9)
Thioredoxin: trdrd_c, NADP+: nadp_c
2 L-Glutamate + NADP+ ⇄ L-Glutamine + 2-Oxoglutarate + NADPH + H+ (1.4.1.13)
L-Glutamate: glu__L_c, NADP+: nadp_c
L-Glutamate + NADP+ + H2O ⇄ 2-Oxoglutarate + Ammonia + NADPH + H+ (1.4.1.13)
L-Glutamate: glu__L_c, NADP+: nadp_c, H2O: h2o_c
L-Glutamate + NADP+ + H2O ⇄ 2-Oxoglutarate + Ammonia + NADPH + H+ (1.4.1.4)
L-Glutamate: glu__L_c, NADP+: nadp_c, H2O: h2o_c
9 Malonyl-CoA + 11 NADPH + 10 H+ + S-Adenosyl-L-methionine + Acyl-carrier protein ⇄ Dihydromonacolin L-[acyl-carrier protein] + 9 CoA + 9 CO2 + 11 NADP+ + S-Adenosyl-L-homocysteine + 6 H2O (2.3.1.161)
S-Adenosyl-L-methionine: amet_c, Malonyl-CoA: malcoa_c, NADPH: nadph_c, H+: h_c, Acyl-carrier protein: ACP_c
2 Malonyl-CoA + Acyl-carrier protein + 2 NADPH + 2 H+ + S-Adenosyl-L-methionine ⇄ (S)-2-Methylbutanoyl-[acp] + 2 CoA + 2 CO2 + 2 NADP+ + S-Adenosyl-L-homocysteine + H2O (2.3.1.244)
S-Adenosyl-L-methionine: amet_c, Malonyl-CoA: malcoa_c, Acyl-carrier protein: ACP_c, NADPH: nadph_c, H+: h_c
5,10-Methylenetetrahydrofolate + dUMP + NADPH + H+ ⇄ Tetrahydrofolate + dTMP + NADP+ (2.1.1.148)
5,10-Methylenetetrahydrofolate: mlthf_c, dUMP: dump_c, NADPH: nadph_c, H+: h_c
Succinyl-CoA + CO2 + NADPH + H+ ⇄ 2-Oxoglutarate + CoA + NADP+ (1.2.1.52)
Succinyl-CoA: succoa_c, CO2: co2_c, NADPH: nadph_c, H+: h_c
L-Glutamine + 2-Oxoglutarate + NADPH + H+ ⇄ 2 L-Glutamate + NADP+ (1.4.1.13)
2-Oxoglutarate: akg_c, L-Glutamine: gln__L_c, NADPH: nadph_c, H+: h_c
2-Oxoglutarate + Ammonia + NADPH + H+ ⇄ L-Glutamate + NADP+ + H2O (1.4.1.13)
2-Oxoglutarate: akg_c, Ammonia: nh4_c, NADPH: nadph_c, H+: h_c
2-Oxoglutarate + Ammonia + NADPH + H+ ⇄ L-Glutamate + NADP+ + H2O (1.4.1.4)
2-Oxoglutarate: akg_c, Ammonia: nh4_c, NADPH: nadph_c, H+: h_c
9 Malonyl-CoA + 11 NADPH + 10 H+ + S-Adenosyl-L-methionine + Acyl-carrier protein ⇄ Dihydromonacolin L-[acyl-carrier protein] + 9 CoA + 9 CO2 + 11 NADP+ + S-Adenosyl-L-homocysteine + 6 H2O (2.3.1.161)
S-Adenosyl-L-methionine: amet_c, Malonyl-CoA: malcoa_c, NADPH: nadph_c, H+: h_c, Acyl-carrier protein: ACP_c
2 Malonyl-CoA + Acyl-carrier protein + 2 NADPH + 2 H+ + S-Adenosyl-L-methionine ⇄ (S)-2-Methylbutanoyl-[acp] + 2 CoA + 2 CO2 + 2 NADP+ + S-Adenosyl-L-homocysteine + H2O (2.3.1.244)
S-Adenosyl-L-methionine: amet_c, Malonyl-CoA: malcoa_c, Acyl-carrier protein: ACP_c, NADPH: nadph_c, H+: h_c
L-Glutamine + 2-Oxoglutarate + NADPH + H+ ⇄ 2 L-Glutamate + NADP+ (1.4.1.13)
2-Oxoglutarate: akg_c, L-Glutamine: gln__L_c, NADPH: nadph_c, H+: h_c
2-Oxoglutarate + Ammonia + NADPH + H+ ⇄ L-Glutamate + NADP+ + H2O (1.4.1.13)
2-Oxoglutarate: akg_c, Ammonia: nh4_c, NADPH: nadph_c, H+: h_c
2-Oxoglutarate + Ammonia + NADPH + H+ ⇄ L-Glutamate + NADP+ + H2O (1.4.1.4)
2-Oxoglutarate: akg_c, Ammonia: nh4_c, NADPH: nadph_c, H+: h_c
2-Oxoglutarate + Ammonia + Hydrogen peroxide ⇄ L-Glutamate + O2 + H2O (1.4.3.11)
2-Oxoglutarate: akg_c, Ammonia: nh4_c, Hydrogen peroxide: h2o2_c
Glyoxylate + Ammonia + Hydrogen peroxide ⇄ Glycine + H2O + O2 (1.4.3.19)
Glyoxylate: glx_c, Ammonia: nh4_c, Hydrogen peroxide: h2o2_c
2-Oxoglutarate + Ammonia + Hydrogen peroxide ⇄ L-Glutamate + O2 + H2O (1.4.3.11)
2-Oxoglutarate: akg_c, Ammonia: nh4_c, Hydrogen peroxide: h2o2_c
Glyoxylate + Ammonia + Hydrogen peroxide ⇄ Glycine + H2O + O2 (1.4.3.19)
Glyoxylate: glx_c, Ammonia: nh4_c, Hydrogen peroxide: h2o2_c
9 Malonyl-CoA + 11 NADPH + 10 H+ + S-Adenosyl-L-methionine + Acyl-carrier protein ⇄ Dihydromonacolin L-[acyl-carrier protein] + 9 CoA + 9 CO2 + 11 NADP+ + S-Adenosyl-L-homocysteine + 6 H2O (2.3.1.161)
S-Adenosyl-L-methionine: amet_c, Malonyl-CoA: malcoa_c, NADPH: nadph_c, H+: h_c, Acyl-carrier protein: ACP_c
2 Malonyl-CoA + Acyl-carrier protein + 2 NADPH + 2 H+ + S-Adenosyl-L-methionine ⇄ (S)-2-Methylbutanoyl-[acp] + 2 CoA + 2 CO2 + 2 NADP+ + S-Adenosyl-L-homocysteine + H2O (2.3.1.244)
S-Adenosyl-L-methionine: amet_c, Malonyl-CoA: malcoa_c, Acyl-carrier protein: ACP_c, NADPH: nadph_c, H+: h_c
9 Malonyl-CoA + 11 NADPH + 10 H+ + S-Adenosyl-L-methionine + Acyl-carrier protein ⇄ Dihydromonacolin L-[acyl-carrier protein] + 9 CoA + 9 CO2 + 11 NADP+ + S-Adenosyl-L-homocysteine + 6 H2O (2.3.1.161)
S-Adenosyl-L-methionine: amet_c, Malonyl-CoA: malcoa_c, NADPH: nadph_c, H+: h_c, Acyl-carrier protein: ACP_c
2 Malonyl-CoA + Acyl-carrier protein + 2 NADPH + 2 H+ + S-Adenosyl-L-methionine ⇄ (S)-2-Methylbutanoyl-[acp] + 2 CoA + 2 CO2 + 2 NADP+ + S-Adenosyl-L-homocysteine + H2O (2.3.1.244)
S-Adenosyl-L-methionine: amet_c, Malonyl-CoA: malcoa_c, Acyl-carrier protein: ACP_c, NADPH: nadph_c, H+: h_c
4-Trimethylammoniobutanoate + 2-Oxoglutarate + O2 ⇄ Carnitine + Succinate + CO2 (1.14.11.1)
2-Oxoglutarate: akg_c, 4-Trimethylammoniobutanoate: gbbtn_c, O2: o2_c
Deoxyuridine + 2-Oxoglutarate + O2 ⇄ Deoxyribonolactone + Uracil + Succinate + CO2 (1.14.11.10)
2-Oxoglutarate: akg_c, Deoxyuridine: duri_c, O2: o2_c
Taurine + 2-Oxoglutarate + O2 ⇄ Sulfite + Aminoacetaldehyde + Succinate + CO2 (1.14.11.17)
2-Oxoglutarate: akg_c, Taurine: taur_c, O2: o2_c
Deoxyguanidinoproclavaminic acid + 2-Oxoglutarate + O2 ⇄ Guanidinoproclavaminic acid + Succinate + CO2 (1.14.11.21)
2-Oxoglutarate: akg_c, O2: o2_c
L-N2-(2-Carboxyethyl)arginine + ATP ⇄ Deoxyguanidinoproclavaminic acid + AMP + Diphosphate (6.3.3.4)
ATP: atp_c
D-Glyceraldehyde 3-phosphate + L-Arginine ⇄ L-N2-(2-Carboxyethyl)arginine + Orthophosphate (2.5.1.66)
D-Glyceraldehyde 3-phosphate: g3p_c, L-Arginine: arg__L_c
Proclavaminic acid + O2 + 2-Oxoglutarate ⇄ Dihydroclavaminic acid + CO2 + Succinate + H2O (1.14.11.21)
2-Oxoglutarate: akg_c, O2: o2_c
Guanidinoproclavaminic acid + H2O ⇄ Proclavaminic acid + Urea (3.5.3.22)
H2O: h2o_c
Deoxyguanidinoproclavaminic acid + 2-Oxoglutarate + O2 ⇄ Guanidinoproclavaminic acid + Succinate + CO2 (1.14.11.21)
2-Oxoglutarate: akg_c, O2: o2_c
L-N2-(2-Carboxyethyl)arginine + ATP ⇄ Deoxyguanidinoproclavaminic acid + AMP + Diphosphate (6.3.3.4)
ATP: atp_c
D-Glyceraldehyde 3-phosphate + L-Arginine ⇄ L-N2-(2-Carboxyethyl)arginine + Orthophosphate (2.5.1.66)
D-Glyceraldehyde 3-phosphate: g3p_c, L-Arginine: arg__L_c
Dihydroclavaminic acid + O2 + 2-Oxoglutarate ⇄ Clavaminic acid + Succinate + CO2 + H2O (1.14.11.21)
2-Oxoglutarate: akg_c, O2: o2_c
Proclavaminic acid + O2 + 2-Oxoglutarate ⇄ Dihydroclavaminic acid + CO2 + Succinate + H2O (1.14.11.21)
O2: o2_c, 2-Oxoglutarate: akg_c
Guanidinoproclavaminic acid + H2O ⇄ Proclavaminic acid + Urea (3.5.3.22)
H2O: h2o_c
Deoxyguanidinoproclavaminic acid + 2-Oxoglutarate + O2 ⇄ Guanidinoproclavaminic acid + Succinate + CO2 (1.14.11.21)
2-Oxoglutarate: akg_c, O2: o2_c
L-N2-(2-Carboxyethyl)arginine + ATP ⇄ Deoxyguanidinoproclavaminic acid + AMP + Diphosphate (6.3.3.4)
ATP: atp_c
D-Glyceraldehyde 3-phosphate + L-Arginine ⇄ L-N2-(2-Carboxyethyl)arginine + Orthophosphate (2.5.1.66)
D-Glyceraldehyde 3-phosphate: g3p_c, L-Arginine: arg__L_c
L-Proline + 2-Oxoglutarate + O2 ⇄ cis-3-Hydroxy-L-proline + Succinate + CO2 (1.14.11.28)
2-Oxoglutarate: akg_c, L-Proline: pro__L_c, O2: o2_c
Deoxyuridine + 2-Oxoglutarate + O2 ⇄ Uridine + Succinate + CO2 (1.14.11.3)
2-Oxoglutarate: akg_c, Deoxyuridine: duri_c, O2: o2_c
L-Asparagine + 2-Oxoglutarate + O2 ⇄ (2S,3S)-3-Hydroxyasparagine + Succinate + CO2 (1.14.11.39)
2-Oxoglutarate: akg_c, L-Asparagine: asn__L_c, O2: o2_c
L-Arginine + 2-Oxoglutarate + O2 ⇄ beta-Hydroxyarginine + Succinate + CO2 (1.14.11.41)
2-Oxoglutarate: akg_c, L-Arginine: arg__L_c, O2: o2_c
L-Isoleucine + 2-Oxoglutarate + O2 ⇄ (4S)-4-Hydroxy-L-isoleucine + Succinate + CO2 (1.14.11.45)
2-Oxoglutarate: akg_c, L-Isoleucine: ile__L_c, O2: o2_c
2-Aminoethylphosphonate + 2-Oxoglutarate + O2 ⇄ (2-Amino-1-hydroxyethyl)phosphonate + Succinate + CO2 (1.14.11.46)
2-Oxoglutarate: akg_c, O2: o2_c
Phosphonoacetaldehyde + L-Alanine ⇄ 2-Aminoethylphosphonate + Pyruvate (2.6.1.37)
L-Alanine: ala__L_c
2-Hydroxyethylphosphonate + NAD+ ⇄ Phosphonoacetaldehyde + NADH + H+ (1.1.1.309)
NAD+: nad_c
Hydroxymethylphosphonate + Formate ⇄ 2-Hydroxyethylphosphonate + O2 (1.13.11.72)
Formate: for_c
Formate + Orthophosphate ⇄ Hydroxymethylphosphonate + O2 (1.13.11.89)
Formate: for_c, Orthophosphate: pi_c
Xanthine + 2-Oxoglutarate + O2 ⇄ Urate + Succinate + CO2 (1.14.11.48)
2-Oxoglutarate: akg_c, Xanthine: xan_c, O2: o2_c
UMP + 2-Oxoglutarate + O2 ⇄ 5'-Dehydrouridine + Succinate + CO2 + Orthophosphate (1.14.11.49)
2-Oxoglutarate: akg_c, UMP: ump_c, O2: o2_c
Ectoine + 2-Oxoglutarate + O2 ⇄ 5-Hydroxyectoine + Succinate + CO2 (1.14.11.55)
2-Oxoglutarate: akg_c, O2: o2_c
N(alpha)-Acetyl-L-2,4-diaminobutyrate ⇄ Ectoine + H2O (3.5.4.44)
L-2,4-Diaminobutanoate + Acetate ⇄ N(alpha)-Acetyl-L-2,4-diaminobutyrate + H2O (3.5.1.125)
Acetate: ac_c
L-Aspartate 4-semialdehyde + L-Alanine ⇄ L-2,4-Diaminobutanoate + Pyruvate (2.6.1.46)
L-Aspartate 4-semialdehyde: aspsa_c, L-Alanine: ala__L_c
L-Proline + 2-Oxoglutarate + O2 ⇄ cis-4-Hydroxy-L-proline + Succinate + CO2 (1.14.11.56)
2-Oxoglutarate: akg_c, L-Proline: pro__L_c, O2: o2_c
L-Proline + 2-Oxoglutarate + O2 ⇄ Hydroxyproline + Succinate + CO2 (1.14.11.57)
2-Oxoglutarate: akg_c, L-Proline: pro__L_c, O2: o2_c
Ornithine lipid + 2-Oxoglutarate + O2 ⇄ 2-Hydroxyornithine lipid + Succinate + CO2 (1.14.11.58)
2-Oxoglutarate: akg_c, O2: o2_c
Lyso-ornithine lipid + Acyl-[acyl-carrier protein] ⇄ Ornithine lipid + Acyl-carrier protein (2.3.1.270)
L-Ornithine + (3R)-3-Hydroxyacyl-[acyl-carrier protein] ⇄ Lyso-ornithine lipid + Acyl-carrier protein (2.3.2.30)
L-Ornithine: orn_c, (3R)-3-Hydroxyacyl-[acyl-carrier protein]: 3haACP_c
trans-2,3-Dehydroacyl-[acyl-carrier protein] + NADH + H+ ⇄ Acyl-[acyl-carrier protein] + NAD+ (1.3.1.9)
NADH: nadh_c, H+: h_c
(3R)-3-Hydroxyacyl-[acyl-carrier protein] ⇄ trans-2,3-Dehydroacyl-[acyl-carrier protein] + H2O (4.2.1.59)
(3R)-3-Hydroxyacyl-[acyl-carrier protein]: 3haACP_c
Thymine + 2-Oxoglutarate + O2 ⇄ 5-Hydroxymethyluracil + Succinate + CO2 (1.14.11.6)
2-Oxoglutarate: akg_c, Thymine: thym_c, O2: o2_c
Feruloyl-CoA + 2-Oxoglutarate + O2 ⇄ 6-Hydroxyferuloyl-CoA + Succinate + CO2 (1.14.11.61)
2-Oxoglutarate: akg_c, O2: o2_c
4-Hydroxy-3-methoxy-benzaldehyde + Acetyl-CoA ⇄ Feruloyl-CoA + H2O (4.1.2.61)
Acetyl-CoA: accoa_c
Vanillate + NADH + H+ ⇄ 4-Hydroxy-3-methoxy-benzaldehyde + NAD+ + H2O (1.2.1.67)
NADH: nadh_c, H+: h_c
3,4-Dihydroxybenzoate + NAD+ + H2O + Formaldehyde ⇄ Vanillate + O2 + NADH + H+ (1.14.13.82)
NAD+: nad_c, H2O: h2o_c, Formaldehyde: fald_c
4-Hydroxybenzoate + O2 + NADPH + H+ ⇄ 3,4-Dihydroxybenzoate + NADP+ + H2O (1.14.13.2)
4-Hydroxybenzoate: 4hbz_c, O2: o2_c, NADPH: nadph_c, H+: h_c
4-Hydroxy-3-methoxyphenyl-beta-hydroxypropanoyl-CoA ⇄ Feruloyl-CoA + H2O (4.1.2.61)
4-Hydroxy-3-methoxy-benzaldehyde + Acetyl-CoA ⇄ 4-Hydroxy-3-methoxyphenyl-beta-hydroxypropanoyl-CoA (4.1.2.61)
Acetyl-CoA: accoa_c
Vanillate + NADH + H+ ⇄ 4-Hydroxy-3-methoxy-benzaldehyde + NAD+ + H2O (1.2.1.67)
NADH: nadh_c, H+: h_c
3,4-Dihydroxybenzoate + NAD+ + H2O + Formaldehyde ⇄ Vanillate + O2 + NADH + H+ (1.14.13.82)
NAD+: nad_c, H2O: h2o_c, Formaldehyde: fald_c
4-Hydroxybenzoate + O2 + NADPH + H+ ⇄ 3,4-Dihydroxybenzoate + NADP+ + H2O (1.14.13.2)
4-Hydroxybenzoate: 4hbz_c, O2: o2_c, NADPH: nadph_c, H+: h_c
p-Coumaroyl-CoA + 2-Oxoglutarate + O2 ⇄ 2,4-Dihydroxycinnamoyl-CoA + Succinate + CO2 (1.14.11.62)
2-Oxoglutarate: akg_c, O2: o2_c
ATP + 4-Coumarate + CoA ⇄ AMP + Diphosphate + p-Coumaroyl-CoA (6.2.1.12)
ATP: atp_c, CoA: coa_c
L-Tyrosine ⇄ 4-Coumarate + Ammonia (4.3.1.23)
L-Tyrosine: tyr__L_c
Glutarate + 2-Oxoglutarate + O2 ⇄ (S)-2-Hydroxyglutarate + Succinate + CO2 (1.14.11.64)
2-Oxoglutarate: akg_c, O2: o2_c
5-Oxopentanoate + NAD+ + H2O ⇄ Glutarate + NADH + H+ (1.2.1.20)
NAD+: nad_c, H2O: h2o_c
5-Aminopentanoate + 2-Oxoglutarate ⇄ 5-Oxopentanoate + L-Glutamate (2.6.1.48)
2-Oxoglutarate: akg_c
5-Aminopentanamide + H2O ⇄ 5-Aminopentanoate + Ammonia (3.5.1.30)
H2O: h2o_c
L-Lysine + O2 ⇄ 5-Aminopentanamide + CO2 + H2O (1.13.12.2)
L-Lysine: lys__L_c, O2: o2_c
Methylphosphonate + 2-Oxoglutarate + O2 ⇄ Hydroxymethylphosphonate + Succinate + CO2 (1.14.11.71)
2-Oxoglutarate: akg_c, O2: o2_c
2-Hydroxyethylphosphonate + O2 ⇄ Methylphosphonate + HCO3- (1.13.11.73)
O2: o2_c
Phosphonoacetaldehyde + NADH + H+ ⇄ 2-Hydroxyethylphosphonate + NAD+ (1.1.1.309)
NADH: nadh_c, H+: h_c
2-Aminoethylphosphonate + Pyruvate ⇄ Phosphonoacetaldehyde + L-Alanine (2.6.1.37)
Pyruvate: pyr_c
(2-Amino-1-hydroxyethyl)phosphonate + Succinate + CO2 ⇄ 2-Aminoethylphosphonate + 2-Oxoglutarate + O2 (1.14.11.46)
Succinate: succ_c, CO2: co2_c
Glycine + Orthophosphate ⇄ (2-Amino-1-hydroxyethyl)phosphonate + O2 (1.13.11.78)
Glycine: gly_c, Orthophosphate: pi_c
L-Isoleucine + 2-Oxoglutarate + O2 ⇄ 3(1)-Hydroxy-L-isoleucine + Succinate + CO2 (1.14.11.74)
2-Oxoglutarate: akg_c, L-Isoleucine: ile__L_c, O2: o2_c
3(1)-Hydroxy-L-isoleucine + 2-Oxoglutarate + O2 ⇄ (4S)-31,4-Dihydroxy-L-isoleucine + Succinate + CO2 (1.14.11.75)
2-Oxoglutarate: akg_c, O2: o2_c
L-Isoleucine + 2-Oxoglutarate + O2 ⇄ 3(1)-Hydroxy-L-isoleucine + Succinate + CO2 (1.14.11.74)
L-Isoleucine: ile__L_c, 2-Oxoglutarate: akg_c, O2: o2_c
L-Glutamate + 2-Oxoglutarate + O2 ⇄ (3R)-3-Hydroxy-L-glutamate + Succinate + CO2 (1.14.11.76)
2-Oxoglutarate: akg_c, L-Glutamate: glu__L_c, O2: o2_c
(2S)-3-(4-Hydroxyphenyl)-2-isocyanopropanoate + 2-Oxoglutarate + O2 ⇄ 4-[(E)-2-Isocyanoethenyl]phenol + Succinate + 2 CO2 + H2O (1.14.20.10)
2-Oxoglutarate: akg_c, O2: o2_c
L-Tyrosine + D-Ribulose 5-phosphate ⇄ (2S)-3-(4-Hydroxyphenyl)-2-isocyanopropanoate + Hydroxyacetone + Formaldehyde + Orthophosphate + H2O (4.1.99.24)
L-Tyrosine: tyr__L_c, D-Ribulose 5-phosphate: ru5p__D_c
(2S)-3-(1H-Indol-3-yl)-2-isocyanopropanoate + 2-Oxoglutarate + O2 ⇄ 3-[(Z)-2-Isocyanoethenyl]-1H-indole + Succinate + 2 CO2 + H2O (1.14.20.11)
2-Oxoglutarate: akg_c, O2: o2_c
L-Tryptophan + D-Ribulose 5-phosphate ⇄ (2S)-3-(1H-Indol-3-yl)-2-isocyanopropanoate + Hydroxyacetone + Formaldehyde + Orthophosphate + H2O (4.1.99.25)
L-Tryptophan: trp__L_c, D-Ribulose 5-phosphate: ru5p__D_c
(2S)-3-(1H-Indol-3-yl)-2-isocyanopropanoate + 2-Oxoglutarate + O2 ⇄ 3-[(E)-2-Isocyanoethenyl]-1H-indole + Succinate + 2 CO2 + H2O (1.14.20.12)
2-Oxoglutarate: akg_c, O2: o2_c
L-Tryptophan + D-Ribulose 5-phosphate ⇄ (2S)-3-(1H-Indol-3-yl)-2-isocyanopropanoate + Hydroxyacetone + Formaldehyde + Orthophosphate + H2O (4.1.99.25)
L-Tryptophan: trp__L_c, D-Ribulose 5-phosphate: ru5p__D_c
12-epi-Fischerindole U + 2-Oxoglutarate + O2 + Cl- ⇄ 12-epi-Fischerindole G + Succinate + CO2 + H2O (1.14.20.14)
2-Oxoglutarate: akg_c, O2: o2_c, Cl-: cl_c
3-Geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole ⇄ 12-epi-Fischerindole U (5.5.1.33)
Geranyl diphosphate + 3-[(Z)-2-Isocyanoethenyl]-1H-indole ⇄ 3-Geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole + Diphosphate (2.5.1.146)
Geranyl diphosphate: grdp_c
(2S)-3-(1H-Indol-3-yl)-2-isocyanopropanoate + 2-Oxoglutarate + O2 ⇄ 3-[(Z)-2-Isocyanoethenyl]-1H-indole + Succinate + 2 CO2 + H2O (1.14.20.11)
2-Oxoglutarate: akg_c, O2: o2_c
L-Tryptophan + D-Ribulose 5-phosphate ⇄ (2S)-3-(1H-Indol-3-yl)-2-isocyanopropanoate + Hydroxyacetone + Formaldehyde + Orthophosphate + H2O (4.1.99.25)
L-Tryptophan: trp__L_c, D-Ribulose 5-phosphate: ru5p__D_c
2-Oxoglutarate + L-Arginine + O2 ⇄ Succinate + CO2 + Guanidine + (S)-1-Pyrroline-5-carboxylate + H2O (1.14.20.7)
2-Oxoglutarate: akg_c, L-Arginine: arg__L_c, O2: o2_c
2-Oxoglutarate + L-Arginine + O2 ⇄ Succinate + CO2 + L-Hydroxyarginine (1.14.20.7)
2-Oxoglutarate: akg_c, L-Arginine: arg__L_c, O2: o2_c
(2S)-3-(4-Hydroxyphenyl)-2-isocyanopropanoate + 2-Oxoglutarate + O2 ⇄ (2E)-3-(4-Hydroxyphenyl)-2-isocyanoprop-2-enoate + Succinate + CO2 + H2O (1.14.20.9)
2-Oxoglutarate: akg_c, O2: o2_c
L-Tyrosine + D-Ribulose 5-phosphate ⇄ (2S)-3-(4-Hydroxyphenyl)-2-isocyanopropanoate + Hydroxyacetone + Formaldehyde + Orthophosphate + H2O (4.1.99.24)
L-Tyrosine: tyr__L_c, D-Ribulose 5-phosphate: ru5p__D_c
2 S-Adenosyl-L-methionine + Precorrin 6Y ⇄ 2 S-Adenosyl-L-homocysteine + Precorrin 8X + CO2 (2.1.1.132)
S-Adenosyl-L-methionine: amet_c
Precorrin 6X + NADPH + H+ ⇄ Precorrin 6Y + NADP+ (1.3.1.54)
NADPH: nadph_c, H+: h_c
Precorrin 5 + S-Adenosyl-L-methionine + H2O ⇄ Precorrin 6X + Acetate + S-Adenosyl-L-homocysteine (2.1.1.152)
S-Adenosyl-L-methionine: amet_c, H2O: h2o_c
S-Adenosyl-L-methionine + Precorrin 4 ⇄ S-Adenosyl-L-homocysteine + Precorrin 5 (2.1.1.133)
S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + Precorrin 3B ⇄ S-Adenosyl-L-homocysteine + Precorrin 4 (2.1.1.131)
S-Adenosyl-L-methionine: amet_c
Precorrin 3A + O2 + NADH + H+ ⇄ Precorrin 3B + NAD+ + H2O (1.14.13.83)
O2: o2_c, NADH: nadh_c, H+: h_c
S-Adenosyl-L-methionine + Precorrin 2 ⇄ S-Adenosyl-L-homocysteine + Precorrin 3A + H+ (2.1.1.130)
S-Adenosyl-L-methionine: amet_c, Precorrin 2: dscl_c
9 Malonyl-CoA + 11 NADPH + 10 H+ + S-Adenosyl-L-methionine + Acyl-carrier protein ⇄ Dihydromonacolin L-[acyl-carrier protein] + 9 CoA + 9 CO2 + 11 NADP+ + S-Adenosyl-L-homocysteine + 6 H2O (2.3.1.161)
S-Adenosyl-L-methionine: amet_c, Malonyl-CoA: malcoa_c, NADPH: nadph_c, H+: h_c, Acyl-carrier protein: ACP_c
2 Malonyl-CoA + Acyl-carrier protein + 2 NADPH + 2 H+ + S-Adenosyl-L-methionine ⇄ (S)-2-Methylbutanoyl-[acp] + 2 CoA + 2 CO2 + 2 NADP+ + S-Adenosyl-L-homocysteine + H2O (2.3.1.244)
S-Adenosyl-L-methionine: amet_c, Malonyl-CoA: malcoa_c, Acyl-carrier protein: ACP_c, NADPH: nadph_c, H+: h_c
Coproporphyrinogen III + 2 S-Adenosyl-L-methionine ⇄ Protoporphyrinogen IX + 2 CO2 + 2 L-Methionine + 2 5'-Deoxyadenosine (1.3.98.3)
S-Adenosyl-L-methionine: amet_c, Coproporphyrinogen III: cpppg3_c
Fe-coproporphyrin III + 2 S-Adenosyl-L-methionine ⇄ Heme + 2 CO2 + 2 5'-Deoxyadenosine + 2 L-Methionine (1.3.98.6)
S-Adenosyl-L-methionine: amet_c
Heme + 2 CO2 + 4 H2O ⇄ Fe-coproporphyrin III + 2 Hydrogen peroxide (1.3.98.5)
Heme: pheme_c, CO2: co2_c, H2O: h2o_c
Harderoheme III + CO2 + 2 H2O ⇄ Fe-coproporphyrin III + Hydrogen peroxide (1.3.98.5)
CO2: co2_c, H2O: h2o_c
Heme + CO2 + 2 H2O ⇄ Harderoheme III + Hydrogen peroxide (1.3.98.5)
Heme: pheme_c, CO2: co2_c, H2O: h2o_c
10-Formyltetrahydrofolate + NADP+ + H2O ⇄ Tetrahydrofolate + CO2 + NADPH + H+ (1.5.1.6)
10-Formyltetrahydrofolate: 10fthf_c, NADP+: nadp_c, H2O: h2o_c
Succinyl-CoA + Glycine ⇄ 5-Aminolevulinate + CoA + CO2 (2.3.1.37)
Succinyl-CoA: succoa_c, Glycine: gly_c
Quinolinate + 5-Phospho-alpha-D-ribose 1-diphosphate ⇄ Nicotinate D-ribonucleotide + Diphosphate + CO2 (2.4.2.19)
5-Phospho-alpha-D-ribose 1-diphosphate: prpp_c, Quinolinate: quln_c
5-Phospho-alpha-D-ribose 1-diphosphate + 4-Hydroxybenzoate ⇄ 4-(beta-D-Ribofuranosyl)phenol 5'-phosphate + CO2 + Diphosphate (2.4.2.54)
5-Phospho-alpha-D-ribose 1-diphosphate: prpp_c, 4-Hydroxybenzoate: 4hbz_c
2 S-Adenosyl-L-methionine + Precorrin 6Y ⇄ 2 S-Adenosyl-L-homocysteine + Precorrin 8X + CO2 (2.1.1.132)
S-Adenosyl-L-methionine: amet_c
Precorrin 6X + NADPH + H+ ⇄ Precorrin 6Y + NADP+ (1.3.1.54)
NADPH: nadph_c, H+: h_c
Precorrin 5 + S-Adenosyl-L-methionine + H2O ⇄ Precorrin 6X + Acetate + S-Adenosyl-L-homocysteine (2.1.1.152)
S-Adenosyl-L-methionine: amet_c, H2O: h2o_c
S-Adenosyl-L-methionine + Precorrin 4 ⇄ S-Adenosyl-L-homocysteine + Precorrin 5 (2.1.1.133)
S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + Precorrin 3B ⇄ S-Adenosyl-L-homocysteine + Precorrin 4 (2.1.1.131)
S-Adenosyl-L-methionine: amet_c
Precorrin 3A + O2 + NADH + H+ ⇄ Precorrin 3B + NAD+ + H2O (1.14.13.83)
O2: o2_c, NADH: nadh_c, H+: h_c
S-Adenosyl-L-methionine + Precorrin 2 ⇄ S-Adenosyl-L-homocysteine + Precorrin 3A + H+ (2.1.1.130)
S-Adenosyl-L-methionine: amet_c, Precorrin 2: dscl_c
9 Malonyl-CoA + 11 NADPH + 10 H+ + S-Adenosyl-L-methionine + Acyl-carrier protein ⇄ Dihydromonacolin L-[acyl-carrier protein] + 9 CoA + 9 CO2 + 11 NADP+ + S-Adenosyl-L-homocysteine + 6 H2O (2.3.1.161)
S-Adenosyl-L-methionine: amet_c, Malonyl-CoA: malcoa_c, NADPH: nadph_c, H+: h_c, Acyl-carrier protein: ACP_c
2 Malonyl-CoA + Acyl-carrier protein + 2 NADPH + 2 H+ + S-Adenosyl-L-methionine ⇄ (S)-2-Methylbutanoyl-[acp] + 2 CoA + 2 CO2 + 2 NADP+ + S-Adenosyl-L-homocysteine + H2O (2.3.1.244)
S-Adenosyl-L-methionine: amet_c, Malonyl-CoA: malcoa_c, Acyl-carrier protein: ACP_c, NADPH: nadph_c, H+: h_c
Coproporphyrinogen III + 2 S-Adenosyl-L-methionine ⇄ Protoporphyrinogen IX + 2 CO2 + 2 L-Methionine + 2 5'-Deoxyadenosine (1.3.98.3)
S-Adenosyl-L-methionine: amet_c, Coproporphyrinogen III: cpppg3_c
Fe-coproporphyrin III + 2 S-Adenosyl-L-methionine ⇄ Heme + 2 CO2 + 2 5'-Deoxyadenosine + 2 L-Methionine (1.3.98.6)
S-Adenosyl-L-methionine: amet_c
Heme + 2 CO2 + 4 H2O ⇄ Fe-coproporphyrin III + 2 Hydrogen peroxide (1.3.98.5)
Heme: pheme_c, CO2: co2_c, H2O: h2o_c
Harderoheme III + CO2 + 2 H2O ⇄ Fe-coproporphyrin III + Hydrogen peroxide (1.3.98.5)
CO2: co2_c, H2O: h2o_c
Heme + CO2 + 2 H2O ⇄ Harderoheme III + Hydrogen peroxide (1.3.98.5)
Heme: pheme_c, CO2: co2_c, H2O: h2o_c
2 ATP + S-Adenosyl-L-methionine + Anthranilate + L-Phenylalanine ⇄ Cyclopeptine + 2 AMP + 2 Diphosphate + S-Adenosyl-L-homocysteine (6.3.2.40)
S-Adenosyl-L-methionine: amet_c, ATP: atp_c, Anthranilate: anth_c, L-Phenylalanine: phe__L_c
2 ATP + S-Adenosyl-L-methionine + Anthranilate + L-Phenylalanine ⇄ Cyclopeptine + 2 AMP + 2 Diphosphate + S-Adenosyl-L-homocysteine (6.3.2.40)
S-Adenosyl-L-methionine: amet_c, ATP: atp_c, Anthranilate: anth_c, L-Phenylalanine: phe__L_c
5-Amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + S-Adenosyl-L-methionine ⇄ 7,8-Didemethyl-8-hydroxy-5-deazariboflavin + Ammonia + L-Methionine + 5'-Deoxyadenosine (4.3.1.32)
S-Adenosyl-L-methionine: amet_c
5-Amino-6-(1-D-ribitylamino)uracil + L-Tyrosine + S-Adenosyl-L-methionine ⇄ 5-Amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + Iminoglycine + L-Methionine + 5'-Deoxyadenosine (2.5.1.147)
5-Amino-6-(1-D-ribitylamino)uracil: 4r5au_c, L-Tyrosine: tyr__L_c, S-Adenosyl-L-methionine: amet_c
L-Glutamate + NADP+ + H2O ⇄ 2-Oxoglutarate + Ammonia + NADPH + H+ (1.4.1.13)
L-Glutamate: glu__L_c, NADP+: nadp_c, H2O: h2o_c
L-Glutamate + NAD+ + H2O ⇄ 2-Oxoglutarate + Ammonia + NADH + H+ (1.4.1.14)
L-Glutamate: glu__L_c, NAD+: nad_c, H2O: h2o_c
L-Glutamate + NAD+ + H2O ⇄ 2-Oxoglutarate + Ammonia + NADH + H+ (1.4.1.2)
L-Glutamate: glu__L_c, NAD+: nad_c, H2O: h2o_c
L-Glutamate + NADP+ + H2O ⇄ 2-Oxoglutarate + Ammonia + NADPH + H+ (1.4.1.4)
L-Glutamate: glu__L_c, NADP+: nadp_c, H2O: h2o_c
L-Glutamate + O2 + H2O ⇄ 2-Oxoglutarate + Ammonia + Hydrogen peroxide (1.4.3.11)
L-Glutamate: glu__L_c, O2: o2_c, H2O: h2o_c
GDP-4-dehydro-6-deoxy-D-mannose + L-Glutamate ⇄ GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + 2-Oxoglutarate + Ammonia (4.2.1.168)
L-Glutamate: glu__L_c, GDP-4-dehydro-6-deoxy-D-mannose: gdpddman_c
L-Alanine + NAD+ + H2O ⇄ Pyruvate + Ammonia + NADH + H+ (1.4.1.1)
L-Alanine: ala__L_c, NAD+: nad_c, H2O: h2o_c
Glycine + H2O + NAD+ ⇄ Glyoxylate + Ammonia + NADH + H+ (1.4.1.10)
Glycine: gly_c, H2O: h2o_c, NAD+: nad_c
Glycine + H2O + O2 ⇄ Glyoxylate + Ammonia + Hydrogen peroxide (1.4.3.19)
Glycine: gly_c, H2O: h2o_c, O2: o2_c
5-Amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + S-Adenosyl-L-methionine ⇄ 7,8-Didemethyl-8-hydroxy-5-deazariboflavin + Ammonia + L-Methionine + 5'-Deoxyadenosine (4.3.1.32)
S-Adenosyl-L-methionine: amet_c
5-Amino-6-(1-D-ribitylamino)uracil + L-Tyrosine + S-Adenosyl-L-methionine ⇄ 5-Amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + Iminoglycine + L-Methionine + 5'-Deoxyadenosine (2.5.1.147)
5-Amino-6-(1-D-ribitylamino)uracil: 4r5au_c, L-Tyrosine: tyr__L_c, S-Adenosyl-L-methionine: amet_c
L-Glutamate + NADP+ + H2O ⇄ 2-Oxoglutarate + Ammonia + NADPH + H+ (1.4.1.13)
L-Glutamate: glu__L_c, NADP+: nadp_c, H2O: h2o_c
L-Glutamate + NAD+ + H2O ⇄ 2-Oxoglutarate + Ammonia + NADH + H+ (1.4.1.14)
L-Glutamate: glu__L_c, NAD+: nad_c, H2O: h2o_c
L-Glutamate + NAD+ + H2O ⇄ 2-Oxoglutarate + Ammonia + NADH + H+ (1.4.1.2)
L-Glutamate: glu__L_c, NAD+: nad_c, H2O: h2o_c
L-Glutamate + NADP+ + H2O ⇄ 2-Oxoglutarate + Ammonia + NADPH + H+ (1.4.1.4)
L-Glutamate: glu__L_c, NADP+: nadp_c, H2O: h2o_c
L-Glutamate + O2 + H2O ⇄ 2-Oxoglutarate + Ammonia + Hydrogen peroxide (1.4.3.11)
L-Glutamate: glu__L_c, O2: o2_c, H2O: h2o_c
GDP-4-dehydro-6-deoxy-D-mannose + L-Glutamate ⇄ GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + 2-Oxoglutarate + Ammonia (4.2.1.168)
L-Glutamate: glu__L_c, GDP-4-dehydro-6-deoxy-D-mannose: gdpddman_c
L-Alanine + NAD+ + H2O ⇄ Pyruvate + Ammonia + NADH + H+ (1.4.1.1)
L-Alanine: ala__L_c, NAD+: nad_c, H2O: h2o_c
Glycine + H2O + NAD+ ⇄ Glyoxylate + Ammonia + NADH + H+ (1.4.1.10)
Glycine: gly_c, H2O: h2o_c, NAD+: nad_c
Glycine + H2O + O2 ⇄ Glyoxylate + Ammonia + Hydrogen peroxide (1.4.3.19)
Glycine: gly_c, H2O: h2o_c, O2: o2_c
2 ATP + S-Adenosyl-L-methionine + Anthranilate + L-Phenylalanine ⇄ Cyclopeptine + 2 AMP + 2 Diphosphate + S-Adenosyl-L-homocysteine (6.3.2.40)
S-Adenosyl-L-methionine: amet_c, ATP: atp_c, Anthranilate: anth_c, L-Phenylalanine: phe__L_c
Adenine + 5-Phospho-alpha-D-ribose 1-diphosphate ⇄ AMP + Diphosphate (2.4.2.7)
5-Phospho-alpha-D-ribose 1-diphosphate: prpp_c, Adenine: ade_c
2 ATP + S-Adenosyl-L-methionine + Anthranilate + L-Phenylalanine ⇄ Cyclopeptine + 2 AMP + 2 Diphosphate + S-Adenosyl-L-homocysteine (6.3.2.40)
S-Adenosyl-L-methionine: amet_c, ATP: atp_c, Anthranilate: anth_c, L-Phenylalanine: phe__L_c
L-Alanine + 2-Oxoglutarate ⇄ Pyruvate + L-Glutamate (2.6.1.2)
2-Oxoglutarate: akg_c, L-Alanine: ala__L_c
L-Alanine + Glyoxylate ⇄ Pyruvate + Glycine (2.6.1.44)
Glyoxylate: glx_c, L-Alanine: ala__L_c
L-Alanine + 2-Oxoglutarate ⇄ Pyruvate + L-Glutamate (2.6.1.2)
2-Oxoglutarate: akg_c, L-Alanine: ala__L_c
L-Alanine + Glyoxylate ⇄ Pyruvate + Glycine (2.6.1.44)
Glyoxylate: glx_c, L-Alanine: ala__L_c
L-Alanine + 2-Oxoglutarate ⇄ Pyruvate + L-Glutamate (2.6.1.2)
L-Alanine: ala__L_c, 2-Oxoglutarate: akg_c
Glycine + 2-Oxoglutarate ⇄ Glyoxylate + L-Glutamate (2.6.1.4)
Glycine: gly_c, 2-Oxoglutarate: akg_c
L-Alanine + 2-Oxoglutarate ⇄ Pyruvate + L-Glutamate (2.6.1.2)
L-Alanine: ala__L_c, 2-Oxoglutarate: akg_c
Glycine + 2-Oxoglutarate ⇄ Glyoxylate + L-Glutamate (2.6.1.4)
Glycine: gly_c, 2-Oxoglutarate: akg_c
Succinyl-CoA + CO2 + NADPH + H+ ⇄ 2-Oxoglutarate + CoA + NADP+ (1.2.1.52)
Succinyl-CoA: succoa_c, CO2: co2_c, NADPH: nadph_c, H+: h_c
Pyruvate + L-Glutamate ⇄ L-Alanine + 2-Oxoglutarate (2.6.1.2)
Pyruvate: pyr_c, L-Glutamate: glu__L_c
Glyoxylate + L-Glutamate ⇄ Glycine + 2-Oxoglutarate (2.6.1.4)
Glyoxylate: glx_c, L-Glutamate: glu__L_c
Pyruvate + L-Glutamate ⇄ L-Alanine + 2-Oxoglutarate (2.6.1.2)
Pyruvate: pyr_c, L-Glutamate: glu__L_c
Glyoxylate + L-Glutamate ⇄ Glycine + 2-Oxoglutarate (2.6.1.4)
Glyoxylate: glx_c, L-Glutamate: glu__L_c
L-Glutamate + O2 + H2O ⇄ 2-Oxoglutarate + Ammonia + Hydrogen peroxide (1.4.3.11)
L-Glutamate: glu__L_c, O2: o2_c, H2O: h2o_c
Glycine + H2O + O2 ⇄ Glyoxylate + Ammonia + Hydrogen peroxide (1.4.3.19)
Glycine: gly_c, H2O: h2o_c, O2: o2_c
L-Glutamate + O2 + H2O ⇄ 2-Oxoglutarate + Ammonia + Hydrogen peroxide (1.4.3.11)
L-Glutamate: glu__L_c, O2: o2_c, H2O: h2o_c
Glycine + H2O + O2 ⇄ Glyoxylate + Ammonia + Hydrogen peroxide (1.4.3.19)
Glycine: gly_c, H2O: h2o_c, O2: o2_c
Fe-coproporphyrin III + 2 S-Adenosyl-L-methionine ⇄ Heme + 2 CO2 + 2 5'-Deoxyadenosine + 2 L-Methionine (1.3.98.6)
S-Adenosyl-L-methionine: amet_c
Heme + 2 CO2 + 4 H2O ⇄ Fe-coproporphyrin III + 2 Hydrogen peroxide (1.3.98.5)
Heme: pheme_c, CO2: co2_c, H2O: h2o_c
Harderoheme III + CO2 + 2 H2O ⇄ Fe-coproporphyrin III + Hydrogen peroxide (1.3.98.5)
CO2: co2_c, H2O: h2o_c
Heme + CO2 + 2 H2O ⇄ Harderoheme III + Hydrogen peroxide (1.3.98.5)
Heme: pheme_c, CO2: co2_c, H2O: h2o_c
Fe-coproporphyrin III + 2 S-Adenosyl-L-methionine ⇄ Heme + 2 CO2 + 2 5'-Deoxyadenosine + 2 L-Methionine (1.3.98.6)
S-Adenosyl-L-methionine: amet_c
Heme + 2 CO2 + 4 H2O ⇄ Fe-coproporphyrin III + 2 Hydrogen peroxide (1.3.98.5)
Heme: pheme_c, CO2: co2_c, H2O: h2o_c
Harderoheme III + CO2 + 2 H2O ⇄ Fe-coproporphyrin III + Hydrogen peroxide (1.3.98.5)
CO2: co2_c, H2O: h2o_c
Heme + CO2 + 2 H2O ⇄ Harderoheme III + Hydrogen peroxide (1.3.98.5)
Heme: pheme_c, CO2: co2_c, H2O: h2o_c
Precorrin 5 + S-Adenosyl-L-methionine + H2O ⇄ Precorrin 6X + Acetate + S-Adenosyl-L-homocysteine (2.1.1.152)
S-Adenosyl-L-methionine: amet_c, H2O: h2o_c
S-Adenosyl-L-methionine + Precorrin 4 ⇄ S-Adenosyl-L-homocysteine + Precorrin 5 (2.1.1.133)
S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + Precorrin 3B ⇄ S-Adenosyl-L-homocysteine + Precorrin 4 (2.1.1.131)
S-Adenosyl-L-methionine: amet_c
Precorrin 3A + O2 + NADH + H+ ⇄ Precorrin 3B + NAD+ + H2O (1.14.13.83)
O2: o2_c, NADH: nadh_c, H+: h_c
S-Adenosyl-L-methionine + Precorrin 2 ⇄ S-Adenosyl-L-homocysteine + Precorrin 3A + H+ (2.1.1.130)
S-Adenosyl-L-methionine: amet_c, Precorrin 2: dscl_c
Precorrin 5 + S-Adenosyl-L-methionine + H2O ⇄ Precorrin 6X + Acetate + S-Adenosyl-L-homocysteine (2.1.1.152)
S-Adenosyl-L-methionine: amet_c, H2O: h2o_c
S-Adenosyl-L-methionine + Precorrin 4 ⇄ S-Adenosyl-L-homocysteine + Precorrin 5 (2.1.1.133)
S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + Precorrin 3B ⇄ S-Adenosyl-L-homocysteine + Precorrin 4 (2.1.1.131)
S-Adenosyl-L-methionine: amet_c
Precorrin 3A + O2 + NADH + H+ ⇄ Precorrin 3B + NAD+ + H2O (1.14.13.83)
O2: o2_c, NADH: nadh_c, H+: h_c
S-Adenosyl-L-methionine + Precorrin 2 ⇄ S-Adenosyl-L-homocysteine + Precorrin 3A + H+ (2.1.1.130)
S-Adenosyl-L-methionine: amet_c, Precorrin 2: dscl_c
L-Aspartate + 2-Oxoglutarate ⇄ Oxaloacetate + L-Glutamate (2.6.1.1)
2-Oxoglutarate: akg_c, L-Aspartate: asp__L_c
Glyoxylate + L-Aspartate ⇄ Glycine + Oxaloacetate (2.6.1.35)
Glyoxylate: glx_c, L-Aspartate: asp__L_c
L-Aspartate + 2-Oxoglutarate ⇄ Oxaloacetate + L-Glutamate (2.6.1.1)
2-Oxoglutarate: akg_c, L-Aspartate: asp__L_c
Glyoxylate + L-Aspartate ⇄ Glycine + Oxaloacetate (2.6.1.35)
Glyoxylate: glx_c, L-Aspartate: asp__L_c
Glyoxylate + L-Glutamate ⇄ Glycine + 2-Oxoglutarate (2.6.1.4)
L-Glutamate: glu__L_c, Glyoxylate: glx_c
L-Alanine + Glyoxylate ⇄ Pyruvate + Glycine (2.6.1.44)
L-Alanine: ala__L_c, Glyoxylate: glx_c
Tetrahydrofolate + L-Serine ⇄ 5,10-Methylenetetrahydrofolate + Glycine + H2O (2.1.2.1)
Tetrahydrofolate: thf_c, L-Serine: ser__L_c
L-Ornithine + Guanidinoacetate ⇄ L-Arginine + Glycine (2.1.4.1)
L-Ornithine: orn_c
S-Adenosyl-L-homocysteine + Creatine ⇄ S-Adenosyl-L-methionine + Guanidinoacetate (2.1.1.2)
S-Adenosyl-L-homocysteine: ahcys_c
Creatinine + H2O ⇄ Creatine (3.5.2.10)
H2O: h2o_c
N-Methylhydantoin + Ammonia ⇄ Creatinine + H2O (3.5.4.21)
Ammonia: nh4_c
ADP + Orthophosphate + N-Carbamoylsarcosine ⇄ ATP + N-Methylhydantoin + 2 H2O (3.5.2.14)
ADP: adp_c, Orthophosphate: pi_c
Sarcosine + CO2 + Ammonia ⇄ N-Carbamoylsarcosine + H2O (3.5.1.59)
Sarcosine: sarcs_c, CO2: co2_c, Ammonia: nh4_c
Glyoxylate + L-Glutamate ⇄ Glycine + 2-Oxoglutarate (2.6.1.4)
L-Glutamate: glu__L_c, Glyoxylate: glx_c
L-Alanine + Glyoxylate ⇄ Pyruvate + Glycine (2.6.1.44)
L-Alanine: ala__L_c, Glyoxylate: glx_c
Pyruvate + L-Glutamate ⇄ L-Alanine + 2-Oxoglutarate (2.6.1.2)
L-Glutamate: glu__L_c, Pyruvate: pyr_c
Pyruvate + Glycine ⇄ L-Alanine + Glyoxylate (2.6.1.44)
Glycine: gly_c, Pyruvate: pyr_c
Pyruvate + L-Glutamate ⇄ L-Alanine + 2-Oxoglutarate (2.6.1.2)
L-Glutamate: glu__L_c, Pyruvate: pyr_c
Pyruvate + Glycine ⇄ L-Alanine + Glyoxylate (2.6.1.44)
Glycine: gly_c, Pyruvate: pyr_c
L-2-Aminoadipate 6-semialdehyde + L-Glutamate ⇄ L-Lysine + 2-Oxoglutarate (2.6.1.36)
L-Glutamate: glu__L_c
(S)-2,3,4,5-Tetrahydropyridine-2-carboxylate + H2O ⇄ L-2-Aminoadipate 6-semialdehyde (1.2.1.31)
H2O: h2o_c
L-Lysine + NAD+ ⇄ (S)-2,3,4,5-Tetrahydropyridine-2-carboxylate + NADH + H+ + Ammonia (1.4.1.18)
L-Lysine: lys__L_c, NAD+: nad_c
L-2-Aminoadipate 6-semialdehyde + L-Alanine ⇄ L-Lysine + Pyruvate (2.6.1.71)
L-Alanine: ala__L_c
(S)-2,3,4,5-Tetrahydropyridine-2-carboxylate + H2O ⇄ L-2-Aminoadipate 6-semialdehyde (1.2.1.31)
H2O: h2o_c
L-Lysine + NAD+ ⇄ (S)-2,3,4,5-Tetrahydropyridine-2-carboxylate + NADH + H+ + Ammonia (1.4.1.18)
L-Lysine: lys__L_c, NAD+: nad_c
L-Ornithine + Homoarginine ⇄ L-Arginine + L-Lysine (2.1.4.3)
L-Ornithine: orn_c
L-Arginine + L-Lysine ⇄ L-Ornithine + Homoarginine (2.1.4.3)
L-Arginine: arg__L_c, L-Lysine: lys__L_c
L-2-Aminoadipate 6-semialdehyde + L-Glutamate ⇄ L-Lysine + 2-Oxoglutarate (2.6.1.36)
L-Glutamate: glu__L_c
(S)-2,3,4,5-Tetrahydropyridine-2-carboxylate + H2O ⇄ L-2-Aminoadipate 6-semialdehyde (1.2.1.31)
H2O: h2o_c
L-Lysine + NAD+ ⇄ (S)-2,3,4,5-Tetrahydropyridine-2-carboxylate + NADH + H+ + Ammonia (1.4.1.18)
L-Lysine: lys__L_c, NAD+: nad_c
L-2-Aminoadipate 6-semialdehyde + L-Alanine ⇄ L-Lysine + Pyruvate (2.6.1.71)
L-Alanine: ala__L_c
(S)-2,3,4,5-Tetrahydropyridine-2-carboxylate + H2O ⇄ L-2-Aminoadipate 6-semialdehyde (1.2.1.31)
H2O: h2o_c
L-Lysine + NAD+ ⇄ (S)-2,3,4,5-Tetrahydropyridine-2-carboxylate + NADH + H+ + Ammonia (1.4.1.18)
L-Lysine: lys__L_c, NAD+: nad_c
Glycine + 2-Oxoglutarate ⇄ Glyoxylate + L-Glutamate (2.6.1.4)
2-Oxoglutarate: akg_c, Glycine: gly_c
Pyruvate + Glycine ⇄ L-Alanine + Glyoxylate (2.6.1.44)
Pyruvate: pyr_c, Glycine: gly_c
Glycine + 2-Oxoglutarate ⇄ Glyoxylate + L-Glutamate (2.6.1.4)
2-Oxoglutarate: akg_c, Glycine: gly_c
Pyruvate + Glycine ⇄ L-Alanine + Glyoxylate (2.6.1.44)
Pyruvate: pyr_c, Glycine: gly_c
Oxaloacetate + L-Glutamate ⇄ L-Aspartate + 2-Oxoglutarate (2.6.1.1)
L-Glutamate: glu__L_c, Oxaloacetate: oaa_c
Glycine + Oxaloacetate ⇄ Glyoxylate + L-Aspartate (2.6.1.35)
Glycine: gly_c, Oxaloacetate: oaa_c
Oxaloacetate + L-Glutamate ⇄ L-Aspartate + 2-Oxoglutarate (2.6.1.1)
L-Glutamate: glu__L_c, Oxaloacetate: oaa_c
Glycine + Oxaloacetate ⇄ Glyoxylate + L-Aspartate (2.6.1.35)
Glycine: gly_c, Oxaloacetate: oaa_c
Thioredoxin + 3'-Phosphoadenylyl sulfate ⇄ Thioredoxin disulfide + Sulfite + Adenosine 3',5'-bisphosphate (1.8.4.8)
Thioredoxin: trdrd_c, 3'-Phosphoadenylyl sulfate: paps_c
Thioredoxin + 3'-Phosphoadenylyl sulfate ⇄ Thioredoxin disulfide + Sulfite + Adenosine 3',5'-bisphosphate (1.8.4.8)
Thioredoxin: trdrd_c, 3'-Phosphoadenylyl sulfate: paps_c
Aminoimidazole ribotide + S-Adenosyl-L-methionine ⇄ 4-Amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 5'-Deoxyadenosine + L-Methionine + Formate + CO (4.1.99.17)
S-Adenosyl-L-methionine: amet_c
1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate ⇄ Aminoimidazole ribotide + CO2 (4.1.1.21)
1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate: 5aizc_c
10-Formyltetrahydrofolate + H2O ⇄ Formate + Tetrahydrofolate (3.5.1.10)
10-Formyltetrahydrofolate: 10fthf_c, H2O: h2o_c
Aminoimidazole ribotide + S-Adenosyl-L-methionine ⇄ 4-Amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 5'-Deoxyadenosine + L-Methionine + Formate + CO (4.1.99.17)
S-Adenosyl-L-methionine: amet_c
1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate ⇄ Aminoimidazole ribotide + CO2 (4.1.1.21)
1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate: 5aizc_c
2 L-Glutamate + NADP+ ⇄ L-Glutamine + 2-Oxoglutarate + NADPH + H+ (1.4.1.13)
L-Glutamate: glu__L_c, NADP+: nadp_c
2 L-Glutamate + NAD+ ⇄ L-Glutamine + 2-Oxoglutarate + NADH + H+ (1.4.1.14)
L-Glutamate: glu__L_c, NAD+: nad_c
2-Oxoglutaramate + L-Alanine ⇄ L-Glutamine + Pyruvate (2.6.1.15)
L-Alanine: ala__L_c
L-Glutamine + Pyruvate ⇄ 2-Oxoglutaramate + L-Alanine (2.6.1.15)
L-Glutamine: gln__L_c, Pyruvate: pyr_c
2 L-Glutamate + NADP+ ⇄ L-Glutamine + 2-Oxoglutarate + NADPH + H+ (1.4.1.13)
L-Glutamate: glu__L_c, NADP+: nadp_c
2 L-Glutamate + NAD+ ⇄ L-Glutamine + 2-Oxoglutarate + NADH + H+ (1.4.1.14)
L-Glutamate: glu__L_c, NAD+: nad_c
2-Oxoglutaramate + L-Alanine ⇄ L-Glutamine + Pyruvate (2.6.1.15)
L-Alanine: ala__L_c
L-Glutamine + Pyruvate ⇄ 2-Oxoglutaramate + L-Alanine (2.6.1.15)
L-Glutamine: gln__L_c, Pyruvate: pyr_c
5,10-Methylenetetrahydrofolate + Glycine + H2O ⇄ Tetrahydrofolate + L-Serine (2.1.2.1)
5,10-Methylenetetrahydrofolate: mlthf_c, Glycine: gly_c, H2O: h2o_c
Hydroxypyruvate + L-Alanine ⇄ L-Serine + Pyruvate (2.6.1.51)
L-Alanine: ala__L_c, Hydroxypyruvate: hpyr_c
Hydroxypyruvate + Glycine ⇄ L-Serine + Glyoxylate (2.6.1.45)
Glycine: gly_c, Hydroxypyruvate: hpyr_c
Hydroxypyruvate + L-Alanine ⇄ L-Serine + Pyruvate (2.6.1.51)
L-Alanine: ala__L_c, Hydroxypyruvate: hpyr_c
Hydroxypyruvate + Glycine ⇄ L-Serine + Glyoxylate (2.6.1.45)
Glycine: gly_c, Hydroxypyruvate: hpyr_c
L-Methionine (S)-S-oxide + Thioredoxin ⇄ L-Methionine + Thioredoxin disulfide + H2O (1.8.4.11)
Thioredoxin: trdrd_c
L-Methionine + Thioredoxin disulfide + H2O ⇄ L-Methionine (S)-S-oxide + Thioredoxin (1.8.4.11)
L-Methionine: met__L_c, Thioredoxin disulfide: trdox_c, H2O: h2o_c
4-Methylthio-2-oxobutanoic acid + Glycine ⇄ L-Methionine + Glyoxylate (2.6.1.73)
Glycine: gly_c
1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one + O2 ⇄ 4-Methylthio-2-oxobutanoic acid + Formate (1.13.11.54)
O2: o2_c
2,3-Diketo-5-methylthiopentyl-1-phosphate + H2O ⇄ 1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one + Orthophosphate (3.1.3.77)
H2O: h2o_c
S-Methyl-5-thio-D-ribulose 1-phosphate ⇄ 2,3-Diketo-5-methylthiopentyl-1-phosphate + H2O (4.2.1.109)
S-Methyl-5-thio-D-ribose 1-phosphate ⇄ S-Methyl-5-thio-D-ribulose 1-phosphate (5.3.1.23)
5'-Methylthioadenosine + Orthophosphate ⇄ Adenine + S-Methyl-5-thio-D-ribose 1-phosphate (2.4.2.28)
5'-Methylthioadenosine: 5mta_c, Orthophosphate: pi_c
2-Hydroxy-3-keto-5-methylthiopentenyl-1-phosphate + H2O ⇄ 1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one + Orthophosphate (3.1.3.77)
H2O: h2o_c
2,3-Diketo-5-methylthiopentyl-1-phosphate ⇄ 2-Hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (3.1.3.77)
S-Methyl-5-thio-D-ribulose 1-phosphate ⇄ 2,3-Diketo-5-methylthiopentyl-1-phosphate + H2O (4.2.1.109)
S-Methyl-5-thio-D-ribose 1-phosphate ⇄ S-Methyl-5-thio-D-ribulose 1-phosphate (5.3.1.23)
5'-Methylthioadenosine + Orthophosphate ⇄ Adenine + S-Methyl-5-thio-D-ribose 1-phosphate (2.4.2.28)
5'-Methylthioadenosine: 5mta_c, Orthophosphate: pi_c
L-Methionine (S)-S-oxide + Thioredoxin ⇄ L-Methionine + Thioredoxin disulfide + H2O (1.8.4.11)
Thioredoxin: trdrd_c
L-Methionine + Thioredoxin disulfide + H2O ⇄ L-Methionine (S)-S-oxide + Thioredoxin (1.8.4.11)
L-Methionine: met__L_c, Thioredoxin disulfide: trdox_c, H2O: h2o_c
4-Methylthio-2-oxobutanoic acid + Glycine ⇄ L-Methionine + Glyoxylate (2.6.1.73)
Glycine: gly_c
1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one + O2 ⇄ 4-Methylthio-2-oxobutanoic acid + Formate (1.13.11.54)
O2: o2_c
2,3-Diketo-5-methylthiopentyl-1-phosphate + H2O ⇄ 1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one + Orthophosphate (3.1.3.77)
H2O: h2o_c
S-Methyl-5-thio-D-ribulose 1-phosphate ⇄ 2,3-Diketo-5-methylthiopentyl-1-phosphate + H2O (4.2.1.109)
S-Methyl-5-thio-D-ribose 1-phosphate ⇄ S-Methyl-5-thio-D-ribulose 1-phosphate (5.3.1.23)
5'-Methylthioadenosine + Orthophosphate ⇄ Adenine + S-Methyl-5-thio-D-ribose 1-phosphate (2.4.2.28)
5'-Methylthioadenosine: 5mta_c, Orthophosphate: pi_c
2-Hydroxy-3-keto-5-methylthiopentenyl-1-phosphate + H2O ⇄ 1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one + Orthophosphate (3.1.3.77)
H2O: h2o_c
2,3-Diketo-5-methylthiopentyl-1-phosphate ⇄ 2-Hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (3.1.3.77)
S-Methyl-5-thio-D-ribulose 1-phosphate ⇄ 2,3-Diketo-5-methylthiopentyl-1-phosphate + H2O (4.2.1.109)
S-Methyl-5-thio-D-ribose 1-phosphate ⇄ S-Methyl-5-thio-D-ribulose 1-phosphate (5.3.1.23)
5'-Methylthioadenosine + Orthophosphate ⇄ Adenine + S-Methyl-5-thio-D-ribose 1-phosphate (2.4.2.28)
5'-Methylthioadenosine: 5mta_c, Orthophosphate: pi_c
Indolepyruvate + L-Glutamate ⇄ L-Tryptophan + 2-Oxoglutarate (2.6.1.27)
L-Glutamate: glu__L_c
L-Tryptophan + 2-Oxoglutarate ⇄ Indolepyruvate + L-Glutamate (2.6.1.27)
L-Tryptophan: trp__L_c, 2-Oxoglutarate: akg_c
Indolepyruvate + L-Alanine ⇄ L-Tryptophan + Pyruvate (2.6.1.99)
L-Alanine: ala__L_c
L-Tryptophan + 2-Oxoglutarate ⇄ Indolepyruvate + L-Glutamate (2.6.1.27)
L-Tryptophan: trp__L_c, 2-Oxoglutarate: akg_c
Indolepyruvate + L-Glutamate ⇄ L-Tryptophan + 2-Oxoglutarate (2.6.1.27)
L-Glutamate: glu__L_c
L-Tryptophan + 2-Oxoglutarate ⇄ Indolepyruvate + L-Glutamate (2.6.1.27)
L-Tryptophan: trp__L_c, 2-Oxoglutarate: akg_c
Indolepyruvate + L-Alanine ⇄ L-Tryptophan + Pyruvate (2.6.1.99)
L-Alanine: ala__L_c
L-Tryptophan + 2-Oxoglutarate ⇄ Indolepyruvate + L-Glutamate (2.6.1.27)
L-Tryptophan: trp__L_c, 2-Oxoglutarate: akg_c
Phenylpyruvate + L-Alanine ⇄ L-Phenylalanine + Pyruvate (2.6.1.58)
L-Alanine: ala__L_c, Phenylpyruvate: phpyr_c
Phenylpyruvate + L-Alanine ⇄ L-Phenylalanine + Pyruvate (2.6.1.58)
L-Alanine: ala__L_c, Phenylpyruvate: phpyr_c
(R)-Lactate + NAD+ ⇄ Pyruvate + NADH + H+ (1.1.1.28)
(R)-Lactate: lac__D_c, NAD+: nad_c
Thioredoxin + NADP+ ⇄ Thioredoxin disulfide + NADPH + H+ (1.8.1.9)
Thioredoxin: trdrd_c, NADP+: nadp_c
S-Adenosyl-L-methionine + Precorrin 2 ⇄ S-Adenosyl-L-homocysteine + Precorrin 3A + H+ (2.1.1.130)
S-Adenosyl-L-methionine: amet_c, Precorrin 2: dscl_c
dTDP-3-amino-3,6-dideoxy-D-glucose + 2 S-Adenosyl-L-methionine ⇄ dTDP-D-mycaminose + 2 S-Adenosyl-L-homocysteine + 2 H+ (2.1.1.235)
S-Adenosyl-L-methionine: amet_c
3,6-Dideoxy-3-oxo-dTDP-D-glucose + L-Glutamate ⇄ dTDP-3-amino-3,6-dideoxy-D-glucose + 2-Oxoglutarate (2.6.1.89)
L-Glutamate: glu__L_c
dTDP-4-oxo-6-deoxy-D-glucose ⇄ 3,6-Dideoxy-3-oxo-dTDP-D-glucose (5.3.2.4)
dTDP-4-oxo-6-deoxy-D-glucose: dtdp4d6dg_c
10-Formyltetrahydrofolate + NADP+ + H2O ⇄ Tetrahydrofolate + CO2 + NADPH + H+ (1.5.1.6)
10-Formyltetrahydrofolate: 10fthf_c, NADP+: nadp_c, H2O: h2o_c
2 L-Glutamate + NADP+ ⇄ L-Glutamine + 2-Oxoglutarate + NADPH + H+ (1.4.1.13)
L-Glutamate: glu__L_c, NADP+: nadp_c
L-Glutamate + NADP+ + H2O ⇄ 2-Oxoglutarate + Ammonia + NADPH + H+ (1.4.1.13)
L-Glutamate: glu__L_c, NADP+: nadp_c, H2O: h2o_c
2 L-Glutamate + NAD+ ⇄ L-Glutamine + 2-Oxoglutarate + NADH + H+ (1.4.1.14)
L-Glutamate: glu__L_c, NAD+: nad_c
L-Glutamate + NAD+ + H2O ⇄ 2-Oxoglutarate + Ammonia + NADH + H+ (1.4.1.14)
L-Glutamate: glu__L_c, NAD+: nad_c, H2O: h2o_c
L-Glutamate + NAD+ + H2O ⇄ 2-Oxoglutarate + Ammonia + NADH + H+ (1.4.1.2)
L-Glutamate: glu__L_c, NAD+: nad_c, H2O: h2o_c
L-Glutamate + NADP+ + H2O ⇄ 2-Oxoglutarate + Ammonia + NADPH + H+ (1.4.1.4)
L-Glutamate: glu__L_c, NADP+: nadp_c, H2O: h2o_c
L-Alanine + NAD+ + H2O ⇄ Pyruvate + Ammonia + NADH + H+ (1.4.1.1)
L-Alanine: ala__L_c, NAD+: nad_c, H2O: h2o_c
Glycine + H2O + NAD+ ⇄ Glyoxylate + Ammonia + NADH + H+ (1.4.1.10)
Glycine: gly_c, H2O: h2o_c, NAD+: nad_c
Tetrahydrofolate + dTMP + NADP+ ⇄ 5,10-Methylenetetrahydrofolate + dUMP + NADPH + H+ (2.1.1.148)
Tetrahydrofolate: thf_c, dTMP: dtmp_c, NADP+: nadp_c
(R)-Lactate + NAD+ ⇄ Pyruvate + NADH + H+ (1.1.1.28)
(R)-Lactate: lac__D_c, NAD+: nad_c
Thioredoxin + NADP+ ⇄ Thioredoxin disulfide + NADPH + H+ (1.8.1.9)
Thioredoxin: trdrd_c, NADP+: nadp_c
S-Adenosyl-L-methionine + Precorrin 2 ⇄ S-Adenosyl-L-homocysteine + Precorrin 3A + H+ (2.1.1.130)
S-Adenosyl-L-methionine: amet_c, Precorrin 2: dscl_c
dTDP-3-amino-3,6-dideoxy-D-glucose + 2 S-Adenosyl-L-methionine ⇄ dTDP-D-mycaminose + 2 S-Adenosyl-L-homocysteine + 2 H+ (2.1.1.235)
S-Adenosyl-L-methionine: amet_c
3,6-Dideoxy-3-oxo-dTDP-D-glucose + L-Glutamate ⇄ dTDP-3-amino-3,6-dideoxy-D-glucose + 2-Oxoglutarate (2.6.1.89)
L-Glutamate: glu__L_c
dTDP-4-oxo-6-deoxy-D-glucose ⇄ 3,6-Dideoxy-3-oxo-dTDP-D-glucose (5.3.2.4)
dTDP-4-oxo-6-deoxy-D-glucose: dtdp4d6dg_c
2 L-Glutamate + NADP+ ⇄ L-Glutamine + 2-Oxoglutarate + NADPH + H+ (1.4.1.13)
L-Glutamate: glu__L_c, NADP+: nadp_c
L-Glutamate + NADP+ + H2O ⇄ 2-Oxoglutarate + Ammonia + NADPH + H+ (1.4.1.13)
L-Glutamate: glu__L_c, NADP+: nadp_c, H2O: h2o_c
2 L-Glutamate + NAD+ ⇄ L-Glutamine + 2-Oxoglutarate + NADH + H+ (1.4.1.14)
L-Glutamate: glu__L_c, NAD+: nad_c
L-Glutamate + NAD+ + H2O ⇄ 2-Oxoglutarate + Ammonia + NADH + H+ (1.4.1.14)
L-Glutamate: glu__L_c, NAD+: nad_c, H2O: h2o_c
L-Glutamate + NAD+ + H2O ⇄ 2-Oxoglutarate + Ammonia + NADH + H+ (1.4.1.2)
L-Glutamate: glu__L_c, NAD+: nad_c, H2O: h2o_c
L-Glutamate + NADP+ + H2O ⇄ 2-Oxoglutarate + Ammonia + NADPH + H+ (1.4.1.4)
L-Glutamate: glu__L_c, NADP+: nadp_c, H2O: h2o_c
L-Alanine + NAD+ + H2O ⇄ Pyruvate + Ammonia + NADH + H+ (1.4.1.1)
L-Alanine: ala__L_c, NAD+: nad_c, H2O: h2o_c
Glycine + H2O + NAD+ ⇄ Glyoxylate + Ammonia + NADH + H+ (1.4.1.10)
Glycine: gly_c, H2O: h2o_c, NAD+: nad_c
3-(4-Hydroxyphenyl)pyruvate + L-Glutamate ⇄ L-Tyrosine + 2-Oxoglutarate (2.6.1.5)
L-Glutamate: glu__L_c, 3-(4-Hydroxyphenyl)pyruvate: 34hpp_c
3-(4-Hydroxyphenyl)pyruvate + L-Glutamate ⇄ L-Tyrosine + 2-Oxoglutarate (2.6.1.5)
L-Glutamate: glu__L_c, 3-(4-Hydroxyphenyl)pyruvate: 34hpp_c
Thioredoxin + 3'-Phosphoadenylyl sulfate ⇄ Thioredoxin disulfide + Sulfite + Adenosine 3',5'-bisphosphate (1.8.4.8)
Thioredoxin: trdrd_c, 3'-Phosphoadenylyl sulfate: paps_c
Taurine + 2-Oxoglutarate + O2 ⇄ Sulfite + Aminoacetaldehyde + Succinate + CO2 (1.14.11.17)
2-Oxoglutarate: akg_c, Taurine: taur_c, O2: o2_c
Thioredoxin + 3'-Phosphoadenylyl sulfate ⇄ Thioredoxin disulfide + Sulfite + Adenosine 3',5'-bisphosphate (1.8.4.8)
Thioredoxin: trdrd_c, 3'-Phosphoadenylyl sulfate: paps_c
Mercaptopyruvate + L-Glutamate ⇄ L-Cysteine + 2-Oxoglutarate (2.6.1.3)
L-Glutamate: glu__L_c, Mercaptopyruvate: mercppyr_c
Mercaptopyruvate + L-Glutamate ⇄ L-Cysteine + 2-Oxoglutarate (2.6.1.3)
L-Glutamate: glu__L_c, Mercaptopyruvate: mercppyr_c
3-Oxopropanoate + L-Glutamate ⇄ beta-Alanine + 2-Oxoglutarate (2.6.1.120)
L-Glutamate: glu__L_c, 3-Oxopropanoate: msa_c
L-Alanine + 3-Oxopropanoate ⇄ Pyruvate + beta-Alanine (2.6.1.18)
L-Alanine: ala__L_c, 3-Oxopropanoate: msa_c
3-Oxopropanoate + L-Glutamate ⇄ beta-Alanine + 2-Oxoglutarate (2.6.1.120)
L-Glutamate: glu__L_c, 3-Oxopropanoate: msa_c
L-Alanine + 3-Oxopropanoate ⇄ Pyruvate + beta-Alanine (2.6.1.18)
L-Alanine: ala__L_c, 3-Oxopropanoate: msa_c
4-Methyl-2-oxopentanoate + L-Glutamate ⇄ L-Leucine + 2-Oxoglutarate (2.6.1.42)
L-Glutamate: glu__L_c, 4-Methyl-2-oxopentanoate: 4mop_c
4-Methyl-2-oxopentanoate + L-Glutamate ⇄ L-Leucine + 2-Oxoglutarate (2.6.1.6)
L-Glutamate: glu__L_c, 4-Methyl-2-oxopentanoate: 4mop_c
4-Methyl-2-oxopentanoate + L-Glutamate ⇄ L-Leucine + 2-Oxoglutarate (2.6.1.42)
L-Glutamate: glu__L_c, 4-Methyl-2-oxopentanoate: 4mop_c
4-Methyl-2-oxopentanoate + L-Glutamate ⇄ L-Leucine + 2-Oxoglutarate (2.6.1.6)
L-Glutamate: glu__L_c, 4-Methyl-2-oxopentanoate: 4mop_c
4-Aminobutyraldehyde + L-Glutamate ⇄ Putrescine + 2-Oxoglutarate (2.6.1.82)
L-Glutamate: glu__L_c, 4-Aminobutyraldehyde: 4abutn_c
4-Aminobutyraldehyde + L-Glutamate ⇄ Putrescine + 2-Oxoglutarate (2.6.1.82)
L-Glutamate: glu__L_c, 4-Aminobutyraldehyde: 4abutn_c
Imidazol-5-yl-pyruvate + L-Glutamate ⇄ L-Histidine + 2-Oxoglutarate (2.6.1.38)
L-Glutamate: glu__L_c
L-Histidine + 2-Oxoglutarate ⇄ Imidazol-5-yl-pyruvate + L-Glutamate (2.6.1.38)
L-Histidine: his__L_c, 2-Oxoglutarate: akg_c
Imidazol-5-yl-pyruvate + L-Glutamate ⇄ L-Histidine + 2-Oxoglutarate (2.6.1.38)
L-Glutamate: glu__L_c
L-Histidine + 2-Oxoglutarate ⇄ Imidazol-5-yl-pyruvate + L-Glutamate (2.6.1.38)
L-Histidine: his__L_c, 2-Oxoglutarate: akg_c
L-Valine + Pyruvate ⇄ 3-Methyl-2-oxobutanoic acid + L-Alanine (2.6.1.66)
Pyruvate: pyr_c, L-Valine: val__L_c
Tetrahydrofolate + 2-Dehydropantoate ⇄ 5,10-Methylenetetrahydrofolate + 3-Methyl-2-oxobutanoic acid + H2O (2.1.2.11)
Tetrahydrofolate: thf_c, 2-Dehydropantoate: 2dhp_c
L-Valine + Pyruvate ⇄ 3-Methyl-2-oxobutanoic acid + L-Alanine (2.6.1.66)
Pyruvate: pyr_c, L-Valine: val__L_c
L-Alanine + 2-Oxo acid ⇄ Pyruvate + L-Amino acid (2.6.1.12)
L-Alanine: ala__L_c
Aldehyde + CO2 ⇄ 2-Oxo acid (4.1.1.1)
CO2: co2_c
Carboxylate + NADH + H+ ⇄ Aldehyde + NAD+ + H2O (1.2.1.3)
NADH: nadh_c, H+: h_c
Triacylglycerol + H2O ⇄ Diacylglycerol + Carboxylate (3.1.1.3)
H2O: h2o_c
1,2-Diacyl-sn-glycerol + Acyl-CoA ⇄ Triacylglycerol + CoA (2.3.1.20)
ADP + Phosphatidate ⇄ ATP + 1,2-Diacyl-sn-glycerol (2.7.1.107)
ADP: adp_c
G00144 + H2O ⇄ 6-(alpha-D-glucosaminyl)-1D-myo-inositol + Phosphatidate (3.1.4.50)
H2O: h2o_c
1-Acyl-sn-glycerol 3-phosphate + CoA ⇄ sn-Glycerol 3-phosphate + Acyl-CoA (2.3.1.15)
CoA: coa_c
Phosphatidate + CoA ⇄ 1-Acyl-sn-glycerol 3-phosphate + Acyl-CoA (2.3.1.51)
CoA: coa_c
G00144 + H2O ⇄ 6-(alpha-D-glucosaminyl)-1D-myo-inositol + Phosphatidate (3.1.4.50)
H2O: h2o_c
L-Alanine + 2-Oxo acid ⇄ Pyruvate + L-Amino acid (2.6.1.12)
L-Alanine: ala__L_c
Aldehyde + CO2 ⇄ 2-Oxo acid (4.1.1.1)
CO2: co2_c
Carboxylate + NADH + H+ ⇄ Aldehyde + NAD+ + H2O (1.2.1.3)
NADH: nadh_c, H+: h_c
Triacylglycerol + H2O ⇄ Diacylglycerol + Carboxylate (3.1.1.3)
H2O: h2o_c
1,2-Diacyl-sn-glycerol + Acyl-CoA ⇄ Triacylglycerol + CoA (2.3.1.20)
ADP + Phosphatidate ⇄ ATP + 1,2-Diacyl-sn-glycerol (2.7.1.107)
ADP: adp_c
G00144 + H2O ⇄ 6-(alpha-D-glucosaminyl)-1D-myo-inositol + Phosphatidate (3.1.4.50)
H2O: h2o_c
1-Acyl-sn-glycerol 3-phosphate + CoA ⇄ sn-Glycerol 3-phosphate + Acyl-CoA (2.3.1.15)
CoA: coa_c
Phosphatidate + CoA ⇄ 1-Acyl-sn-glycerol 3-phosphate + Acyl-CoA (2.3.1.51)
CoA: coa_c
G00144 + H2O ⇄ 6-(alpha-D-glucosaminyl)-1D-myo-inositol + Phosphatidate (3.1.4.50)
H2O: h2o_c
L-Phenylalanine + Pyruvate ⇄ Phenylpyruvate + L-Alanine (2.6.1.58)
Pyruvate: pyr_c, L-Phenylalanine: phe__L_c
L-Phenylalanine + Pyruvate ⇄ Phenylpyruvate + L-Alanine (2.6.1.58)
Pyruvate: pyr_c, L-Phenylalanine: phe__L_c
L-Serine + Pyruvate ⇄ Hydroxypyruvate + L-Alanine (2.6.1.51)
Pyruvate: pyr_c, L-Serine: ser__L_c
L-Serine + Glyoxylate ⇄ Hydroxypyruvate + Glycine (2.6.1.45)
Glyoxylate: glx_c, L-Serine: ser__L_c
L-Serine + Pyruvate ⇄ Hydroxypyruvate + L-Alanine (2.6.1.51)
Pyruvate: pyr_c, L-Serine: ser__L_c
L-Serine + Glyoxylate ⇄ Hydroxypyruvate + Glycine (2.6.1.45)
Glyoxylate: glx_c, L-Serine: ser__L_c
3-Methyl-2-oxobutanoic acid + L-Alanine ⇄ L-Valine + Pyruvate (2.6.1.66)
L-Alanine: ala__L_c, 3-Methyl-2-oxobutanoic acid: 3mob_c
3-Methyl-2-oxobutanoic acid + L-Alanine ⇄ L-Valine + Pyruvate (2.6.1.66)
L-Alanine: ala__L_c, 3-Methyl-2-oxobutanoic acid: 3mob_c
S-Adenosyl-L-methionine + Glycine ⇄ S-Adenosyl-L-homocysteine + Sarcosine (2.1.1.156)
S-Adenosyl-L-methionine: amet_c, Glycine: gly_c
S-Adenosyl-L-methionine + Glycine ⇄ S-Adenosyl-L-homocysteine + Sarcosine (2.1.1.162)
S-Adenosyl-L-methionine: amet_c, Glycine: gly_c
S-Adenosyl-L-methionine + Glycine ⇄ S-Adenosyl-L-homocysteine + Sarcosine (2.1.1.20)
S-Adenosyl-L-methionine: amet_c, Glycine: gly_c
S-Adenosyl-L-methionine + Glycine ⇄ S-Adenosyl-L-homocysteine + Sarcosine (2.1.1.156)
S-Adenosyl-L-methionine: amet_c, Glycine: gly_c
S-Adenosyl-L-methionine + Glycine ⇄ S-Adenosyl-L-homocysteine + Sarcosine (2.1.1.162)
S-Adenosyl-L-methionine: amet_c, Glycine: gly_c
S-Adenosyl-L-methionine + Glycine ⇄ S-Adenosyl-L-homocysteine + Sarcosine (2.1.1.20)
S-Adenosyl-L-methionine: amet_c, Glycine: gly_c
Sarcosine + Orthophosphate + Thioredoxin ⇄ Acetyl phosphate + Methylamine + Thioredoxin disulfide + H2O (1.21.4.3)
Thioredoxin: trdrd_c, Sarcosine: sarcs_c, Orthophosphate: pi_c
Sarcosine + Orthophosphate + Thioredoxin ⇄ Acetyl phosphate + Methylamine + Thioredoxin disulfide + H2O (1.21.4.3)
Thioredoxin: trdrd_c, Sarcosine: sarcs_c, Orthophosphate: pi_c
beta-Alanine + 2-Oxoglutarate ⇄ 3-Oxopropanoate + L-Glutamate (2.6.1.120)
2-Oxoglutarate: akg_c, beta-Alanine: ala_B_c
Pyruvate + beta-Alanine ⇄ L-Alanine + 3-Oxopropanoate (2.6.1.18)
Pyruvate: pyr_c, beta-Alanine: ala_B_c
beta-Alanine + 2-Oxoglutarate ⇄ 3-Oxopropanoate + L-Glutamate (2.6.1.120)
2-Oxoglutarate: akg_c, beta-Alanine: ala_B_c
Pyruvate + beta-Alanine ⇄ L-Alanine + 3-Oxopropanoate (2.6.1.18)
Pyruvate: pyr_c, beta-Alanine: ala_B_c
Sarcosine + Orthophosphate + Thioredoxin ⇄ Acetyl phosphate + Methylamine + Thioredoxin disulfide + H2O (1.21.4.3)
Thioredoxin: trdrd_c, Sarcosine: sarcs_c, Orthophosphate: pi_c
Betaine + Orthophosphate + Thioredoxin ⇄ Acetyl phosphate + Trimethylamine + Thioredoxin disulfide + H2O (1.21.4.4)
Thioredoxin: trdrd_c, Betaine: glyb_c, Orthophosphate: pi_c
Sarcosine + Orthophosphate + Thioredoxin ⇄ Acetyl phosphate + Methylamine + Thioredoxin disulfide + H2O (1.21.4.3)
Thioredoxin: trdrd_c, Sarcosine: sarcs_c, Orthophosphate: pi_c
Betaine + Orthophosphate + Thioredoxin ⇄ Acetyl phosphate + Trimethylamine + Thioredoxin disulfide + H2O (1.21.4.4)
Thioredoxin: trdrd_c, Betaine: glyb_c, Orthophosphate: pi_c
4-Aminobutanoate + 2-Oxoglutarate ⇄ Succinate semialdehyde + L-Glutamate (2.6.1.19)
2-Oxoglutarate: akg_c, 4-Aminobutanoate: 4abut_c
4-Aminobutanoate + Pyruvate ⇄ Succinate semialdehyde + L-Alanine (2.6.1.96)
Pyruvate: pyr_c, 4-Aminobutanoate: 4abut_c
4-Aminobutanoate + Glyoxylate ⇄ Succinate semialdehyde + Glycine (2.6.1.96)
Glyoxylate: glx_c, 4-Aminobutanoate: 4abut_c
4-Aminobutanoate + 2-Oxoglutarate ⇄ Succinate semialdehyde + L-Glutamate (2.6.1.19)
2-Oxoglutarate: akg_c, 4-Aminobutanoate: 4abut_c
4-Aminobutanoate + Pyruvate ⇄ Succinate semialdehyde + L-Alanine (2.6.1.96)
Pyruvate: pyr_c, 4-Aminobutanoate: 4abut_c
4-Aminobutanoate + Glyoxylate ⇄ Succinate semialdehyde + Glycine (2.6.1.96)
Glyoxylate: glx_c, 4-Aminobutanoate: 4abut_c
L-Leucine + 2-Oxoglutarate ⇄ 4-Methyl-2-oxopentanoate + L-Glutamate (2.6.1.42)
2-Oxoglutarate: akg_c, L-Leucine: leu__L_c
L-Leucine + 2-Oxoglutarate ⇄ 4-Methyl-2-oxopentanoate + L-Glutamate (2.6.1.6)
2-Oxoglutarate: akg_c, L-Leucine: leu__L_c
L-Leucine + 2-Oxoglutarate ⇄ 4-Methyl-2-oxopentanoate + L-Glutamate (2.6.1.42)
2-Oxoglutarate: akg_c, L-Leucine: leu__L_c
L-Leucine + 2-Oxoglutarate ⇄ 4-Methyl-2-oxopentanoate + L-Glutamate (2.6.1.6)
2-Oxoglutarate: akg_c, L-Leucine: leu__L_c
Aminoimidazole ribotide + S-Adenosyl-L-methionine ⇄ 4-Amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 5'-Deoxyadenosine + L-Methionine + Formate + CO (4.1.99.17)
S-Adenosyl-L-methionine: amet_c
1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate ⇄ Aminoimidazole ribotide + CO2 (4.1.1.21)
1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate: 5aizc_c
Aminoimidazole ribotide + S-Adenosyl-L-methionine ⇄ 4-Amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 5'-Deoxyadenosine + L-Methionine + Formate + CO (4.1.99.17)
S-Adenosyl-L-methionine: amet_c
1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate ⇄ Aminoimidazole ribotide + CO2 (4.1.1.21)
1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate: 5aizc_c
Sulfoacetaldehyde + L-Glutamate ⇄ Taurine + 2-Oxoglutarate (2.6.1.55)
L-Glutamate: glu__L_c
2-Hydroxyethanesulfonate + NADP+ ⇄ Sulfoacetaldehyde + NADPH + H+ (1.1.1.313)
2-Hydroxyethanesulfonate: isetac_c, NADP+: nadp_c
Sulfoacetaldehyde + L-Alanine ⇄ Taurine + Pyruvate (2.6.1.77)
L-Alanine: ala__L_c
2-Hydroxyethanesulfonate + NADP+ ⇄ Sulfoacetaldehyde + NADPH + H+ (1.1.1.313)
2-Hydroxyethanesulfonate: isetac_c, NADP+: nadp_c
Sulfoacetaldehyde + L-Glutamate ⇄ Taurine + 2-Oxoglutarate (2.6.1.55)
L-Glutamate: glu__L_c
2-Hydroxyethanesulfonate + NADP+ ⇄ Sulfoacetaldehyde + NADPH + H+ (1.1.1.313)
2-Hydroxyethanesulfonate: isetac_c, NADP+: nadp_c
Sulfoacetaldehyde + L-Alanine ⇄ Taurine + Pyruvate (2.6.1.77)
L-Alanine: ala__L_c
2-Hydroxyethanesulfonate + NADP+ ⇄ Sulfoacetaldehyde + NADPH + H+ (1.1.1.313)
2-Hydroxyethanesulfonate: isetac_c, NADP+: nadp_c
Pyridoxamine + Pyruvate ⇄ Pyridoxal + L-Alanine (2.6.1.30)
Pyruvate: pyr_c, Pyridoxamine: pydam_c
Pyridoxamine + Pyruvate ⇄ Pyridoxal + L-Alanine (2.6.1.30)
Pyruvate: pyr_c, Pyridoxamine: pydam_c
L-Arogenate + 2-Oxoglutarate ⇄ Prephenate + L-Glutamate (2.6.1.79)
2-Oxoglutarate: akg_c
L-Tyrosine + CO2 + NADH + H+ ⇄ L-Arogenate + NAD+ (1.3.1.43)
L-Tyrosine: tyr__L_c, CO2: co2_c, NADH: nadh_c, H+: h_c
L-Arogenate + 2-Oxoglutarate ⇄ Prephenate + L-Glutamate (2.6.1.79)
2-Oxoglutarate: akg_c
L-Tyrosine + CO2 + NADH + H+ ⇄ L-Arogenate + NAD+ (1.3.1.43)
L-Tyrosine: tyr__L_c, CO2: co2_c, NADH: nadh_c, H+: h_c
L-2-Aminoadipate + 2-Oxoglutarate ⇄ 2-Oxoadipate + L-Glutamate (2.6.1.39)
2-Oxoglutarate: akg_c
L-2-Aminoadipate 6-semialdehyde + NADP+ + AMP + Diphosphate ⇄ L-2-Aminoadipate + NADPH + H+ + ATP (1.2.1.95)
NADP+: nadp_c, AMP: amp_c, Diphosphate: ppi_c
(S)-2,3,4,5-Tetrahydropyridine-2-carboxylate + H2O ⇄ L-2-Aminoadipate 6-semialdehyde (1.2.1.31)
H2O: h2o_c
L-Lysine + NAD+ ⇄ (S)-2,3,4,5-Tetrahydropyridine-2-carboxylate + NADH + H+ + Ammonia (1.4.1.18)
L-Lysine: lys__L_c, NAD+: nad_c
L-2-Aminoadipate + 2-Oxoglutarate ⇄ 2-Oxoadipate + L-Glutamate (2.6.1.39)
2-Oxoglutarate: akg_c
L-2-Aminoadipate 6-semialdehyde + NADP+ + AMP + Diphosphate ⇄ L-2-Aminoadipate + NADPH + H+ + ATP (1.2.1.95)
NADP+: nadp_c, AMP: amp_c, Diphosphate: ppi_c
(S)-2,3,4,5-Tetrahydropyridine-2-carboxylate + H2O ⇄ L-2-Aminoadipate 6-semialdehyde (1.2.1.31)
H2O: h2o_c
L-Lysine + NAD+ ⇄ (S)-2,3,4,5-Tetrahydropyridine-2-carboxylate + NADH + H+ + Ammonia (1.4.1.18)
L-Lysine: lys__L_c, NAD+: nad_c
L-Tryptophan + 2-Oxoglutarate ⇄ Indolepyruvate + L-Glutamate (2.6.1.27)
2-Oxoglutarate: akg_c, L-Tryptophan: trp__L_c
L-Tryptophan + Pyruvate ⇄ Indolepyruvate + L-Alanine (2.6.1.99)
Pyruvate: pyr_c, L-Tryptophan: trp__L_c
L-Tryptophan + 2-Oxoglutarate ⇄ Indolepyruvate + L-Glutamate (2.6.1.27)
2-Oxoglutarate: akg_c, L-Tryptophan: trp__L_c
L-Tryptophan + Pyruvate ⇄ Indolepyruvate + L-Alanine (2.6.1.99)
Pyruvate: pyr_c, L-Tryptophan: trp__L_c
3-Aminobutanoyl-CoA + 2-Oxoglutarate ⇄ Acetoacetyl-CoA + L-Glutamate (2.6.1.111)
2-Oxoglutarate: akg_c
Acetoacetyl-CoA + L-Glutamate ⇄ 3-Aminobutanoyl-CoA + 2-Oxoglutarate (2.6.1.111)
Acetoacetyl-CoA: aacoa_c, L-Glutamate: glu__L_c
3-Aminobutanoyl-CoA + 2-Oxoglutarate ⇄ Acetoacetyl-CoA + L-Glutamate (2.6.1.111)
2-Oxoglutarate: akg_c
Acetoacetyl-CoA + L-Glutamate ⇄ 3-Aminobutanoyl-CoA + 2-Oxoglutarate (2.6.1.111)
Acetoacetyl-CoA: aacoa_c, L-Glutamate: glu__L_c
Succinate semialdehyde + L-Glutamate ⇄ 4-Aminobutanoate + 2-Oxoglutarate (2.6.1.19)
L-Glutamate: glu__L_c, Succinate semialdehyde: sucsal_c
Succinate semialdehyde + L-Alanine ⇄ 4-Aminobutanoate + Pyruvate (2.6.1.96)
L-Alanine: ala__L_c, Succinate semialdehyde: sucsal_c
Succinate semialdehyde + Glycine ⇄ 4-Aminobutanoate + Glyoxylate (2.6.1.96)
Glycine: gly_c, Succinate semialdehyde: sucsal_c
Succinate semialdehyde + L-Glutamate ⇄ 4-Aminobutanoate + 2-Oxoglutarate (2.6.1.19)
L-Glutamate: glu__L_c, Succinate semialdehyde: sucsal_c
Succinate semialdehyde + L-Alanine ⇄ 4-Aminobutanoate + Pyruvate (2.6.1.96)
L-Alanine: ala__L_c, Succinate semialdehyde: sucsal_c
Succinate semialdehyde + Glycine ⇄ 4-Aminobutanoate + Glyoxylate (2.6.1.96)
Glycine: gly_c, Succinate semialdehyde: sucsal_c
dUMP + 5,10-Methylenetetrahydrofolate ⇄ Dihydrofolate + dTMP (2.1.1.45)
5,10-Methylenetetrahydrofolate: mlthf_c, dUMP: dump_c
5,10-Methylenetetrahydrofolate + dUMP + NADPH + H+ ⇄ Tetrahydrofolate + dTMP + NADP+ (2.1.1.148)
5,10-Methylenetetrahydrofolate: mlthf_c, dUMP: dump_c, NADPH: nadph_c, H+: h_c
dUMP + 5,10-Methylenetetrahydrofolate ⇄ Dihydrofolate + dTMP (2.1.1.45)
5,10-Methylenetetrahydrofolate: mlthf_c, dUMP: dump_c
Succinyl-CoA + Glycine ⇄ 5-Aminolevulinate + CoA + CO2 (2.3.1.37)
Succinyl-CoA: succoa_c, Glycine: gly_c
4,5-Dioxopentanoate + L-Alanine ⇄ 5-Aminolevulinate + Pyruvate (2.6.1.43)
L-Alanine: ala__L_c
5-Aminolevulinate + Pyruvate ⇄ 4,5-Dioxopentanoate + L-Alanine (2.6.1.43)
5-Aminolevulinate: 5aop_c, Pyruvate: pyr_c
4,5-Dioxopentanoate + L-Alanine ⇄ 5-Aminolevulinate + Pyruvate (2.6.1.43)
L-Alanine: ala__L_c
5-Aminolevulinate + Pyruvate ⇄ 4,5-Dioxopentanoate + L-Alanine (2.6.1.43)
5-Aminolevulinate: 5aop_c, Pyruvate: pyr_c
5-Oxopentanoate + L-Glutamate ⇄ 5-Aminopentanoate + 2-Oxoglutarate (2.6.1.48)
L-Glutamate: glu__L_c
Glutarate + NADH + H+ ⇄ 5-Oxopentanoate + NAD+ + H2O (1.2.1.20)
NADH: nadh_c, H+: h_c
(S)-2-Hydroxyglutarate + Succinate + CO2 ⇄ Glutarate + 2-Oxoglutarate + O2 (1.14.11.64)
(S)-2-Hydroxyglutarate: S2hglut_c, Succinate: succ_c, CO2: co2_c
5-Oxopentanoate + L-Glutamate ⇄ 5-Aminopentanoate + 2-Oxoglutarate (2.6.1.48)
L-Glutamate: glu__L_c
Glutarate + NADH + H+ ⇄ 5-Oxopentanoate + NAD+ + H2O (1.2.1.20)
NADH: nadh_c, H+: h_c
(S)-2-Hydroxyglutarate + Succinate + CO2 ⇄ Glutarate + 2-Oxoglutarate + O2 (1.14.11.64)
(S)-2-Hydroxyglutarate: S2hglut_c, Succinate: succ_c, CO2: co2_c
N-Acetyl-L-glutamate 5-semialdehyde + L-Glutamate ⇄ N-Acetylornithine + 2-Oxoglutarate (2.6.1.11)
L-Glutamate: glu__L_c, N-Acetyl-L-glutamate 5-semialdehyde: acg5sa_c
N-Acetyl-L-glutamate 5-semialdehyde + L-Glutamate ⇄ N-Acetylornithine + 2-Oxoglutarate (2.6.1.11)
L-Glutamate: glu__L_c, N-Acetyl-L-glutamate 5-semialdehyde: acg5sa_c
2-Oxoglutarate + L-2,4-Diaminobutanoate ⇄ L-Glutamate + L-Aspartate 4-semialdehyde (2.6.1.76)
2-Oxoglutarate: akg_c
L-Aspartate 4-semialdehyde + L-Alanine ⇄ L-2,4-Diaminobutanoate + Pyruvate (2.6.1.46)
L-Aspartate 4-semialdehyde: aspsa_c, L-Alanine: ala__L_c
L-2,4-Diaminobutanoate + Pyruvate ⇄ L-Aspartate 4-semialdehyde + L-Alanine (2.6.1.46)
Pyruvate: pyr_c
L-Aspartate 4-semialdehyde + L-Alanine ⇄ L-2,4-Diaminobutanoate + Pyruvate (2.6.1.46)
L-Aspartate 4-semialdehyde: aspsa_c, L-Alanine: ala__L_c
2-Oxoglutarate + L-2,4-Diaminobutanoate ⇄ L-Glutamate + L-Aspartate 4-semialdehyde (2.6.1.76)
2-Oxoglutarate: akg_c
L-Aspartate 4-semialdehyde + L-Alanine ⇄ L-2,4-Diaminobutanoate + Pyruvate (2.6.1.46)
L-Aspartate 4-semialdehyde: aspsa_c, L-Alanine: ala__L_c
L-2,4-Diaminobutanoate + Pyruvate ⇄ L-Aspartate 4-semialdehyde + L-Alanine (2.6.1.46)
Pyruvate: pyr_c
L-Aspartate 4-semialdehyde + L-Alanine ⇄ L-2,4-Diaminobutanoate + Pyruvate (2.6.1.46)
L-Aspartate 4-semialdehyde: aspsa_c, L-Alanine: ala__L_c
Pyridoxal + L-Alanine ⇄ Pyridoxamine + Pyruvate (2.6.1.30)
L-Alanine: ala__L_c, Pyridoxal: pydx_c
Pyridoxal + L-Alanine ⇄ Pyridoxamine + Pyruvate (2.6.1.30)
L-Alanine: ala__L_c, Pyridoxal: pydx_c
Putrescine + 2-Oxoglutarate ⇄ 4-Aminobutyraldehyde + L-Glutamate (2.6.1.82)
2-Oxoglutarate: akg_c, Putrescine: ptrc_c
Putrescine + 2-Oxoglutarate ⇄ 4-Aminobutyraldehyde + L-Glutamate (2.6.1.82)
2-Oxoglutarate: akg_c, Putrescine: ptrc_c
Betaine + Orthophosphate + Thioredoxin ⇄ Acetyl phosphate + Trimethylamine + Thioredoxin disulfide + H2O (1.21.4.4)
Thioredoxin: trdrd_c, Betaine: glyb_c, Orthophosphate: pi_c
Betaine + Orthophosphate + Thioredoxin ⇄ Acetyl phosphate + Trimethylamine + Thioredoxin disulfide + H2O (1.21.4.4)
Thioredoxin: trdrd_c, Betaine: glyb_c, Orthophosphate: pi_c
S-Adenosyl-L-methionine + Methanethiol ⇄ S-Adenosyl-L-homocysteine + Dimethyl sulfide (2.1.1.334)
S-Adenosyl-L-methionine: amet_c
Hydrogen sulfide + Formaldehyde + Hydrogen peroxide ⇄ Methanethiol + O2 + H2O (1.8.3.4)
Hydrogen sulfide: h2s_c, Formaldehyde: fald_c, Hydrogen peroxide: h2o2_c
S-Adenosyl-L-methionine + Methanethiol ⇄ S-Adenosyl-L-homocysteine + Dimethyl sulfide (2.1.1.334)
S-Adenosyl-L-methionine: amet_c
Hydrogen sulfide + Formaldehyde + Hydrogen peroxide ⇄ Methanethiol + O2 + H2O (1.8.3.4)
Hydrogen sulfide: h2s_c, Formaldehyde: fald_c, Hydrogen peroxide: h2o2_c
Taurine + 2-Oxoglutarate ⇄ Sulfoacetaldehyde + L-Glutamate (2.6.1.55)
2-Oxoglutarate: akg_c, Taurine: taur_c
Taurine + Pyruvate ⇄ Sulfoacetaldehyde + L-Alanine (2.6.1.77)
Pyruvate: pyr_c, Taurine: taur_c
Taurine + 2-Oxoglutarate ⇄ Sulfoacetaldehyde + L-Glutamate (2.6.1.55)
2-Oxoglutarate: akg_c, Taurine: taur_c
Taurine + Pyruvate ⇄ Sulfoacetaldehyde + L-Alanine (2.6.1.77)
Pyruvate: pyr_c, Taurine: taur_c
2,3,4,5-Tetrahydrodipicolinate + L-Glutamate + H2O ⇄ LL-2,6-Diaminoheptanedioate + 2-Oxoglutarate (2.6.1.83)
L-Glutamate: glu__L_c, 2,3,4,5-Tetrahydrodipicolinate: thdp_c, H2O: h2o_c
2,3,4,5-Tetrahydrodipicolinate + L-Glutamate + H2O ⇄ LL-2,6-Diaminoheptanedioate + 2-Oxoglutarate (2.6.1.83)
L-Glutamate: glu__L_c, 2,3,4,5-Tetrahydrodipicolinate: thdp_c, H2O: h2o_c
2 S-Adenosyl-L-methionine + Sarcosine ⇄ 2 S-Adenosyl-L-homocysteine + Betaine (2.1.1.157)
S-Adenosyl-L-methionine: amet_c, Sarcosine: sarcs_c
S-Adenosyl-L-methionine + N,N-Dimethylglycine ⇄ S-Adenosyl-L-homocysteine + Betaine (2.1.1.157)
S-Adenosyl-L-methionine: amet_c
Sarcosine + Formaldehyde + Hydrogen peroxide ⇄ N,N-Dimethylglycine + H2O + O2 (1.5.3.10)
Sarcosine: sarcs_c, Formaldehyde: fald_c, Hydrogen peroxide: h2o2_c
S-Adenosyl-L-methionine + N,N-Dimethylglycine ⇄ S-Adenosyl-L-homocysteine + Betaine (2.1.1.161)
S-Adenosyl-L-methionine: amet_c
Sarcosine + Formaldehyde + Hydrogen peroxide ⇄ N,N-Dimethylglycine + H2O + O2 (1.5.3.10)
Sarcosine: sarcs_c, Formaldehyde: fald_c, Hydrogen peroxide: h2o2_c
3 S-Adenosyl-L-methionine + Glycine ⇄ 3 S-Adenosyl-L-homocysteine + Betaine (2.1.1.162)
S-Adenosyl-L-methionine: amet_c, Glycine: gly_c
S-Adenosyl-L-methionine + N,N-Dimethylglycine ⇄ S-Adenosyl-L-homocysteine + Betaine (2.1.1.162)
S-Adenosyl-L-methionine: amet_c
Sarcosine + Formaldehyde + Hydrogen peroxide ⇄ N,N-Dimethylglycine + H2O + O2 (1.5.3.10)
Sarcosine: sarcs_c, Formaldehyde: fald_c, Hydrogen peroxide: h2o2_c
2 S-Adenosyl-L-methionine + Sarcosine ⇄ 2 S-Adenosyl-L-homocysteine + Betaine (2.1.1.157)
S-Adenosyl-L-methionine: amet_c, Sarcosine: sarcs_c
S-Adenosyl-L-methionine + N,N-Dimethylglycine ⇄ S-Adenosyl-L-homocysteine + Betaine (2.1.1.157)
S-Adenosyl-L-methionine: amet_c
Sarcosine + Formaldehyde + Hydrogen peroxide ⇄ N,N-Dimethylglycine + H2O + O2 (1.5.3.10)
Sarcosine: sarcs_c, Formaldehyde: fald_c, Hydrogen peroxide: h2o2_c
S-Adenosyl-L-methionine + N,N-Dimethylglycine ⇄ S-Adenosyl-L-homocysteine + Betaine (2.1.1.161)
S-Adenosyl-L-methionine: amet_c
Sarcosine + Formaldehyde + Hydrogen peroxide ⇄ N,N-Dimethylglycine + H2O + O2 (1.5.3.10)
Sarcosine: sarcs_c, Formaldehyde: fald_c, Hydrogen peroxide: h2o2_c
3 S-Adenosyl-L-methionine + Glycine ⇄ 3 S-Adenosyl-L-homocysteine + Betaine (2.1.1.162)
S-Adenosyl-L-methionine: amet_c, Glycine: gly_c
S-Adenosyl-L-methionine + N,N-Dimethylglycine ⇄ S-Adenosyl-L-homocysteine + Betaine (2.1.1.162)
S-Adenosyl-L-methionine: amet_c
Sarcosine + Formaldehyde + Hydrogen peroxide ⇄ N,N-Dimethylglycine + H2O + O2 (1.5.3.10)
Sarcosine: sarcs_c, Formaldehyde: fald_c, Hydrogen peroxide: h2o2_c
(S)-Ureidoglycine + Glyoxylate ⇄ Glycine + Oxalureate (2.6.1.112)
Glyoxylate: glx_c
Allantoate + Orthophosphate ⇄ (S)-Ureidoglycine + Carbamoyl phosphate (2.1.3.16)
Allantoate: alltt_c, Orthophosphate: pi_c
(S)-Ureidoglycine + Glyoxylate ⇄ Glycine + Oxalureate (2.6.1.112)
Glyoxylate: glx_c
Allantoate + Orthophosphate ⇄ (S)-Ureidoglycine + Carbamoyl phosphate (2.1.3.16)
Allantoate: alltt_c, Orthophosphate: pi_c
Prephenate + L-Glutamate ⇄ L-Arogenate + 2-Oxoglutarate (2.6.1.79)
L-Glutamate: glu__L_c, Prephenate: pphn_c
Prephenate + L-Glutamate ⇄ L-Arogenate + 2-Oxoglutarate (2.6.1.79)
L-Glutamate: glu__L_c, Prephenate: pphn_c
4-Methylthio-2-oxobutanoic acid + L-Alanine ⇄ D-Methionine + Pyruvate (2.6.1.41)
L-Alanine: ala__L_c
1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one + O2 ⇄ 4-Methylthio-2-oxobutanoic acid + Formate (1.13.11.54)
O2: o2_c
2,3-Diketo-5-methylthiopentyl-1-phosphate + H2O ⇄ 1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one + Orthophosphate (3.1.3.77)
H2O: h2o_c
S-Methyl-5-thio-D-ribulose 1-phosphate ⇄ 2,3-Diketo-5-methylthiopentyl-1-phosphate + H2O (4.2.1.109)
S-Methyl-5-thio-D-ribose 1-phosphate ⇄ S-Methyl-5-thio-D-ribulose 1-phosphate (5.3.1.23)
5'-Methylthioadenosine + Orthophosphate ⇄ Adenine + S-Methyl-5-thio-D-ribose 1-phosphate (2.4.2.28)
5'-Methylthioadenosine: 5mta_c, Orthophosphate: pi_c
2-Hydroxy-3-keto-5-methylthiopentenyl-1-phosphate + H2O ⇄ 1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one + Orthophosphate (3.1.3.77)
H2O: h2o_c
2,3-Diketo-5-methylthiopentyl-1-phosphate ⇄ 2-Hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (3.1.3.77)
S-Methyl-5-thio-D-ribulose 1-phosphate ⇄ 2,3-Diketo-5-methylthiopentyl-1-phosphate + H2O (4.2.1.109)
S-Methyl-5-thio-D-ribose 1-phosphate ⇄ S-Methyl-5-thio-D-ribulose 1-phosphate (5.3.1.23)
5'-Methylthioadenosine + Orthophosphate ⇄ Adenine + S-Methyl-5-thio-D-ribose 1-phosphate (2.4.2.28)
5'-Methylthioadenosine: 5mta_c, Orthophosphate: pi_c
4-Methylthio-2-oxobutanoic acid + L-Alanine ⇄ D-Methionine + Pyruvate (2.6.1.41)
L-Alanine: ala__L_c
1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one + O2 ⇄ 4-Methylthio-2-oxobutanoic acid + Formate (1.13.11.54)
O2: o2_c
2,3-Diketo-5-methylthiopentyl-1-phosphate + H2O ⇄ 1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one + Orthophosphate (3.1.3.77)
H2O: h2o_c
S-Methyl-5-thio-D-ribulose 1-phosphate ⇄ 2,3-Diketo-5-methylthiopentyl-1-phosphate + H2O (4.2.1.109)
S-Methyl-5-thio-D-ribose 1-phosphate ⇄ S-Methyl-5-thio-D-ribulose 1-phosphate (5.3.1.23)
5'-Methylthioadenosine + Orthophosphate ⇄ Adenine + S-Methyl-5-thio-D-ribose 1-phosphate (2.4.2.28)
5'-Methylthioadenosine: 5mta_c, Orthophosphate: pi_c
2-Hydroxy-3-keto-5-methylthiopentenyl-1-phosphate + H2O ⇄ 1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one + Orthophosphate (3.1.3.77)
H2O: h2o_c
2,3-Diketo-5-methylthiopentyl-1-phosphate ⇄ 2-Hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (3.1.3.77)
S-Methyl-5-thio-D-ribulose 1-phosphate ⇄ 2,3-Diketo-5-methylthiopentyl-1-phosphate + H2O (4.2.1.109)
S-Methyl-5-thio-D-ribose 1-phosphate ⇄ S-Methyl-5-thio-D-ribulose 1-phosphate (5.3.1.23)
5'-Methylthioadenosine + Orthophosphate ⇄ Adenine + S-Methyl-5-thio-D-ribose 1-phosphate (2.4.2.28)
5'-Methylthioadenosine: 5mta_c, Orthophosphate: pi_c
L-Glutamine + Pyruvate ⇄ 2-Oxoglutaramate + L-Alanine (2.6.1.15)
Pyruvate: pyr_c, L-Glutamine: gln__L_c
L-Glutamine + Pyruvate ⇄ 2-Oxoglutaramate + L-Alanine (2.6.1.15)
Pyruvate: pyr_c, L-Glutamine: gln__L_c
2-Oxoadipate + L-Glutamate ⇄ L-2-Aminoadipate + 2-Oxoglutarate (2.6.1.39)
L-Glutamate: glu__L_c
Homoisocitrate + NAD+ ⇄ 2-Oxoadipate + CO2 + NADH + H+ (1.1.1.87)
NAD+: nad_c
(Z)-But-1-ene-1,2,4-tricarboxylate + H2O ⇄ Homoisocitrate (4.2.1.36)
H2O: h2o_c
(R)-2-Hydroxybutane-1,2,4-tricarboxylate ⇄ (Z)-But-1-ene-1,2,4-tricarboxylate + H2O (4.2.1.114)
Acetyl-CoA + H2O + 2-Oxoglutarate ⇄ (R)-2-Hydroxybutane-1,2,4-tricarboxylate + CoA (2.3.3.14)
Acetyl-CoA: accoa_c, H2O: h2o_c, 2-Oxoglutarate: akg_c
2-Oxoadipate + L-Glutamate ⇄ L-2-Aminoadipate + 2-Oxoglutarate (2.6.1.39)
L-Glutamate: glu__L_c
Homoisocitrate + NAD+ ⇄ 2-Oxoadipate + CO2 + NADH + H+ (1.1.1.87)
NAD+: nad_c
(Z)-But-1-ene-1,2,4-tricarboxylate + H2O ⇄ Homoisocitrate (4.2.1.36)
H2O: h2o_c
(R)-2-Hydroxybutane-1,2,4-tricarboxylate ⇄ (Z)-But-1-ene-1,2,4-tricarboxylate + H2O (4.2.1.114)
Acetyl-CoA + H2O + 2-Oxoglutarate ⇄ (R)-2-Hydroxybutane-1,2,4-tricarboxylate + CoA (2.3.3.14)
Acetyl-CoA: accoa_c, H2O: h2o_c, 2-Oxoglutarate: akg_c
L-Cysteine + 2-Oxoglutarate ⇄ Mercaptopyruvate + L-Glutamate (2.6.1.3)
2-Oxoglutarate: akg_c, L-Cysteine: cys__L_c
L-Cysteine + 2-Oxoglutarate ⇄ Mercaptopyruvate + L-Glutamate (2.6.1.3)
2-Oxoglutarate: akg_c, L-Cysteine: cys__L_c
S-Adenosyl-L-methionine + Nicotinate ⇄ S-Adenosyl-L-homocysteine + N-Methylnicotinate (2.1.1.7)
S-Adenosyl-L-methionine: amet_c, Nicotinate: nac_c
S-Adenosyl-L-methionine + Nicotinate ⇄ S-Adenosyl-L-homocysteine + N-Methylnicotinate (2.1.1.7)
S-Adenosyl-L-methionine: amet_c, Nicotinate: nac_c
3-Phosphonooxypyruvate + L-Glutamate ⇄ O-Phospho-L-serine + 2-Oxoglutarate (2.6.1.52)
L-Glutamate: glu__L_c, 3-Phosphonooxypyruvate: 3php_c
3-Phosphonooxypyruvate + L-Glutamate ⇄ O-Phospho-L-serine + 2-Oxoglutarate (2.6.1.52)
L-Glutamate: glu__L_c, 3-Phosphonooxypyruvate: 3php_c
S-Adenosyl-L-methionine + Dimethyl sulfide ⇄ S-Adenosyl-L-homocysteine + Trimethylsulfonium (2.1.1.96)
S-Adenosyl-L-methionine: amet_c, Dimethyl sulfide: dms_c
Dimethyl sulfide + 5-Methyltetrahydrofolate ⇄ Trimethylsulfonium + Tetrahydrofolate (2.1.1.19)
5-Methyltetrahydrofolate: 5mthf_c, Dimethyl sulfide: dms_c
S-Adenosyl-L-methionine + Dimethyl sulfide ⇄ S-Adenosyl-L-homocysteine + Trimethylsulfonium (2.1.1.96)
S-Adenosyl-L-methionine: amet_c, Dimethyl sulfide: dms_c
Dimethyl sulfide + 5-Methyltetrahydrofolate ⇄ Trimethylsulfonium + Tetrahydrofolate (2.1.1.19)
5-Methyltetrahydrofolate: 5mthf_c, Dimethyl sulfide: dms_c
2 S-Adenosyl-L-methionine + Glycine ⇄ 2 S-Adenosyl-L-homocysteine + N,N-Dimethylglycine (2.1.1.156)
S-Adenosyl-L-methionine: amet_c, Glycine: gly_c
S-Adenosyl-L-methionine + Sarcosine ⇄ S-Adenosyl-L-homocysteine + N,N-Dimethylglycine (2.1.1.156)
S-Adenosyl-L-methionine: amet_c, Sarcosine: sarcs_c
S-Adenosyl-L-methionine + Sarcosine ⇄ S-Adenosyl-L-homocysteine + N,N-Dimethylglycine (2.1.1.157)
S-Adenosyl-L-methionine: amet_c, Sarcosine: sarcs_c
S-Adenosyl-L-methionine + Sarcosine ⇄ S-Adenosyl-L-homocysteine + N,N-Dimethylglycine (2.1.1.162)
S-Adenosyl-L-methionine: amet_c, Sarcosine: sarcs_c
2 S-Adenosyl-L-methionine + Glycine ⇄ 2 S-Adenosyl-L-homocysteine + N,N-Dimethylglycine (2.1.1.156)
S-Adenosyl-L-methionine: amet_c, Glycine: gly_c
S-Adenosyl-L-methionine + Sarcosine ⇄ S-Adenosyl-L-homocysteine + N,N-Dimethylglycine (2.1.1.156)
S-Adenosyl-L-methionine: amet_c, Sarcosine: sarcs_c
S-Adenosyl-L-methionine + Sarcosine ⇄ S-Adenosyl-L-homocysteine + N,N-Dimethylglycine (2.1.1.157)
S-Adenosyl-L-methionine: amet_c, Sarcosine: sarcs_c
S-Adenosyl-L-methionine + Sarcosine ⇄ S-Adenosyl-L-homocysteine + N,N-Dimethylglycine (2.1.1.162)
S-Adenosyl-L-methionine: amet_c, Sarcosine: sarcs_c
Coproporphyrinogen III + 2 S-Adenosyl-L-methionine ⇄ Protoporphyrinogen IX + 2 CO2 + 2 L-Methionine + 2 5'-Deoxyadenosine (1.3.98.3)
S-Adenosyl-L-methionine: amet_c, Coproporphyrinogen III: cpppg3_c
Coproporphyrinogen III + 2 S-Adenosyl-L-methionine ⇄ Protoporphyrinogen IX + 2 CO2 + 2 L-Methionine + 2 5'-Deoxyadenosine (1.3.98.3)
S-Adenosyl-L-methionine: amet_c, Coproporphyrinogen III: cpppg3_c
3-(Imidazol-4-yl)-2-oxopropyl phosphate + L-Glutamate ⇄ L-Histidinol phosphate + 2-Oxoglutarate (2.6.1.9)
L-Glutamate: glu__L_c, 3-(Imidazol-4-yl)-2-oxopropyl phosphate: imacp_c
3-(Imidazol-4-yl)-2-oxopropyl phosphate + L-Glutamate ⇄ L-Histidinol phosphate + 2-Oxoglutarate (2.6.1.9)
L-Glutamate: glu__L_c, 3-(Imidazol-4-yl)-2-oxopropyl phosphate: imacp_c
Ornithine + 2-Oxoglutarate ⇄ 5-Amino-2-oxopentanoic acid + L-Glutamate (2.6.1.8)
2-Oxoglutarate: akg_c, Ornithine: orn_c
Ornithine + 2-Oxoglutarate ⇄ 5-Amino-2-oxopentanoic acid + L-Glutamate (2.6.1.8)
2-Oxoglutarate: akg_c, Ornithine: orn_c
L-Tyrosine + 2-Oxoglutarate ⇄ 3-(4-Hydroxyphenyl)pyruvate + L-Glutamate (2.6.1.5)
2-Oxoglutarate: akg_c, L-Tyrosine: tyr__L_c
L-Tyrosine + 2-Oxoglutarate ⇄ 3-(4-Hydroxyphenyl)pyruvate + L-Glutamate (2.6.1.5)
2-Oxoglutarate: akg_c, L-Tyrosine: tyr__L_c
D-Methionine + Pyruvate ⇄ 4-Methylthio-2-oxobutanoic acid + L-Alanine (2.6.1.41)
Pyruvate: pyr_c, D-Methionine: met__D_c
L-Methionine + Glyoxylate ⇄ 4-Methylthio-2-oxobutanoic acid + Glycine (2.6.1.73)
Glyoxylate: glx_c, L-Methionine: met__L_c
D-Methionine + Pyruvate ⇄ 4-Methylthio-2-oxobutanoic acid + L-Alanine (2.6.1.41)
Pyruvate: pyr_c, D-Methionine: met__D_c
L-Methionine + Glyoxylate ⇄ 4-Methylthio-2-oxobutanoic acid + Glycine (2.6.1.73)
Glyoxylate: glx_c, L-Methionine: met__L_c
2-Methyl-3-oxopropanoate + L-Alanine ⇄ (R)-3-Amino-2-methylpropanoate + Pyruvate (2.6.1.40)
L-Alanine: ala__L_c
Propanoyl-CoA + CO2 + NADH + H+ ⇄ 2-Methyl-3-oxopropanoate + CoA + NAD+ (1.2.1.27)
Propanoyl-CoA: ppcoa_c, CO2: co2_c, NADH: nadh_c, H+: h_c
2-Methyl-3-oxopropanoate + L-Alanine ⇄ (R)-3-Amino-2-methylpropanoate + Pyruvate (2.6.1.40)
L-Alanine: ala__L_c
Propanoyl-CoA + CO2 + NADH + H+ ⇄ 2-Methyl-3-oxopropanoate + CoA + NAD+ (1.2.1.27)
Propanoyl-CoA: ppcoa_c, CO2: co2_c, NADH: nadh_c, H+: h_c
S-Adenosyl-L-methionine + Ethanolamine phosphate ⇄ S-Adenosyl-L-homocysteine + N-Methylethanolamine phosphate (2.1.1.103)
S-Adenosyl-L-methionine: amet_c
ATP + Ethanolamine ⇄ ADP + Ethanolamine phosphate (2.7.1.82)
ATP: atp_c, Ethanolamine: etha_c
S-Adenosyl-L-methionine + Ethanolamine phosphate ⇄ S-Adenosyl-L-homocysteine + N-Methylethanolamine phosphate (2.1.1.103)
S-Adenosyl-L-methionine: amet_c
ATP + Ethanolamine ⇄ ADP + Ethanolamine phosphate (2.7.1.82)
ATP: atp_c, Ethanolamine: etha_c
GDP-4-amino-4,6-dideoxy-alpha-D-mannose + 2-Oxoglutarate ⇄ GDP-4-dehydro-6-deoxy-D-mannose + L-Glutamate (2.6.1.102)
2-Oxoglutarate: akg_c
GDP-4-dehydro-6-deoxy-D-mannose + L-Glutamate ⇄ GDP-4-amino-4,6-dideoxy-alpha-D-mannose + 2-Oxoglutarate (2.6.1.102)
GDP-4-dehydro-6-deoxy-D-mannose: gdpddman_c, L-Glutamate: glu__L_c
GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + 2-Oxoglutarate + Ammonia ⇄ GDP-4-dehydro-6-deoxy-D-mannose + L-Glutamate (4.2.1.168)
2-Oxoglutarate: akg_c, Ammonia: nh4_c
GDP-4-dehydro-6-deoxy-D-mannose + L-Glutamate ⇄ GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + 2-Oxoglutarate + Ammonia (4.2.1.168)
GDP-4-dehydro-6-deoxy-D-mannose: gdpddman_c, L-Glutamate: glu__L_c
GDP-4-amino-4,6-dideoxy-alpha-D-mannose + 2-Oxoglutarate ⇄ GDP-4-dehydro-6-deoxy-D-mannose + L-Glutamate (2.6.1.102)
2-Oxoglutarate: akg_c
GDP-4-dehydro-6-deoxy-D-mannose + L-Glutamate ⇄ GDP-4-amino-4,6-dideoxy-alpha-D-mannose + 2-Oxoglutarate (2.6.1.102)
GDP-4-dehydro-6-deoxy-D-mannose: gdpddman_c, L-Glutamate: glu__L_c
GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + 2-Oxoglutarate + Ammonia ⇄ GDP-4-dehydro-6-deoxy-D-mannose + L-Glutamate (4.2.1.168)
2-Oxoglutarate: akg_c, Ammonia: nh4_c
GDP-4-dehydro-6-deoxy-D-mannose + L-Glutamate ⇄ GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + 2-Oxoglutarate + Ammonia (4.2.1.168)
GDP-4-dehydro-6-deoxy-D-mannose: gdpddman_c, L-Glutamate: glu__L_c
S-Adenosyl-L-methionine + Phosphatidylethanolamine ⇄ S-Adenosyl-L-homocysteine + Phosphatidyl-N-methylethanolamine (2.1.1.17)
S-Adenosyl-L-methionine: amet_c
CDP-ethanolamine + 1,2-Diacyl-sn-glycerol ⇄ CMP + Phosphatidylethanolamine (2.7.8.1)
CTP + Ethanolamine phosphate ⇄ Diphosphate + CDP-ethanolamine (2.7.7.14)
CTP: ctp_c
ATP + Ethanolamine ⇄ ADP + Ethanolamine phosphate (2.7.1.82)
ATP: atp_c, Ethanolamine: etha_c
Triacylglycerol + CoA ⇄ 1,2-Diacyl-sn-glycerol + Acyl-CoA (2.3.1.20)
CoA: coa_c
Diacylglycerol + Carboxylate ⇄ Triacylglycerol + H2O (3.1.1.3)
1-Acylglycerol + Carboxylate ⇄ Diacylglycerol + H2O (3.1.1.79)
1-Acyl-sn-glycerol 3-phosphate + H2O ⇄ 1-Acylglycerol + Orthophosphate (3.1.3.106)
H2O: h2o_c
Phosphatidate + CoA ⇄ 1-Acyl-sn-glycerol 3-phosphate + Acyl-CoA (2.3.1.51)
CoA: coa_c
G00144 + H2O ⇄ 6-(alpha-D-glucosaminyl)-1D-myo-inositol + Phosphatidate (3.1.4.50)
H2O: h2o_c
Phosphatidylcholine + H2O ⇄ 1-Acyl-sn-glycero-3-phosphocholine + Carboxylate (3.1.1.4)
H2O: h2o_c
Phosphatidate + Choline ⇄ Phosphatidylcholine + H2O (3.1.4.4)
Choline: chol_c
G00144 + H2O ⇄ 6-(alpha-D-glucosaminyl)-1D-myo-inositol + Phosphatidate (3.1.4.50)
H2O: h2o_c
Phosphatidylcholine + H2O ⇄ 1-Acyl-sn-glycero-3-phosphocholine + Carboxylate (3.1.1.4)
H2O: h2o_c
CDP-diacylglycerol + Choline ⇄ CMP + Phosphatidylcholine (2.7.8.24)
Choline: chol_c
CTP + Phosphatidate ⇄ Diphosphate + CDP-diacylglycerol (2.7.7.41)
CTP: ctp_c
G00144 + H2O ⇄ 6-(alpha-D-glucosaminyl)-1D-myo-inositol + Phosphatidate (3.1.4.50)
H2O: h2o_c
S-Adenosyl-L-methionine + Phosphatidylethanolamine ⇄ S-Adenosyl-L-homocysteine + Phosphatidyl-N-methylethanolamine (2.1.1.17)
S-Adenosyl-L-methionine: amet_c
CDP-ethanolamine + 1,2-Diacyl-sn-glycerol ⇄ CMP + Phosphatidylethanolamine (2.7.8.1)
CTP + Ethanolamine phosphate ⇄ Diphosphate + CDP-ethanolamine (2.7.7.14)
CTP: ctp_c
ATP + Ethanolamine ⇄ ADP + Ethanolamine phosphate (2.7.1.82)
ATP: atp_c, Ethanolamine: etha_c
Triacylglycerol + CoA ⇄ 1,2-Diacyl-sn-glycerol + Acyl-CoA (2.3.1.20)
CoA: coa_c
Diacylglycerol + Carboxylate ⇄ Triacylglycerol + H2O (3.1.1.3)
1-Acylglycerol + Carboxylate ⇄ Diacylglycerol + H2O (3.1.1.79)
1-Acyl-sn-glycerol 3-phosphate + H2O ⇄ 1-Acylglycerol + Orthophosphate (3.1.3.106)
H2O: h2o_c
Phosphatidate + CoA ⇄ 1-Acyl-sn-glycerol 3-phosphate + Acyl-CoA (2.3.1.51)
CoA: coa_c
G00144 + H2O ⇄ 6-(alpha-D-glucosaminyl)-1D-myo-inositol + Phosphatidate (3.1.4.50)
H2O: h2o_c
Phosphatidylcholine + H2O ⇄ 1-Acyl-sn-glycero-3-phosphocholine + Carboxylate (3.1.1.4)
H2O: h2o_c
Phosphatidate + Choline ⇄ Phosphatidylcholine + H2O (3.1.4.4)
Choline: chol_c
G00144 + H2O ⇄ 6-(alpha-D-glucosaminyl)-1D-myo-inositol + Phosphatidate (3.1.4.50)
H2O: h2o_c
Phosphatidylcholine + H2O ⇄ 1-Acyl-sn-glycero-3-phosphocholine + Carboxylate (3.1.1.4)
H2O: h2o_c
CDP-diacylglycerol + Choline ⇄ CMP + Phosphatidylcholine (2.7.8.24)
Choline: chol_c
CTP + Phosphatidate ⇄ Diphosphate + CDP-diacylglycerol (2.7.7.41)
CTP: ctp_c
G00144 + H2O ⇄ 6-(alpha-D-glucosaminyl)-1D-myo-inositol + Phosphatidate (3.1.4.50)
H2O: h2o_c
N-Acetylornithine + 2-Oxoglutarate ⇄ N-Acetyl-L-glutamate 5-semialdehyde + L-Glutamate (2.6.1.11)
2-Oxoglutarate: akg_c, N-Acetylornithine: acorn_c
N-Acetylornithine + 2-Oxoglutarate ⇄ N-Acetyl-L-glutamate 5-semialdehyde + L-Glutamate (2.6.1.11)
2-Oxoglutarate: akg_c, N-Acetylornithine: acorn_c
L-Kynurenine + 2-Oxoglutarate ⇄ 4-(2-Aminophenyl)-2,4-dioxobutanoate + L-Glutamate (2.6.1.7)
2-Oxoglutarate: akg_c
L-Formylkynurenine + H2O ⇄ Formate + L-Kynurenine (3.5.1.9)
H2O: h2o_c
L-Tryptophan + O2 ⇄ L-Formylkynurenine (1.13.11.11)
L-Tryptophan: trp__L_c, O2: o2_c
L-Kynurenine + Glyoxylate ⇄ 4-(2-Aminophenyl)-2,4-dioxobutanoate + Glycine (2.6.1.63)
Glyoxylate: glx_c
L-Formylkynurenine + H2O ⇄ Formate + L-Kynurenine (3.5.1.9)
H2O: h2o_c
L-Tryptophan + O2 ⇄ L-Formylkynurenine (1.13.11.11)
L-Tryptophan: trp__L_c, O2: o2_c
L-Kynurenine + 2-Oxoglutarate ⇄ 4-(2-Aminophenyl)-2,4-dioxobutanoate + L-Glutamate (2.6.1.7)
2-Oxoglutarate: akg_c
L-Formylkynurenine + H2O ⇄ Formate + L-Kynurenine (3.5.1.9)
H2O: h2o_c
L-Tryptophan + O2 ⇄ L-Formylkynurenine (1.13.11.11)
L-Tryptophan: trp__L_c, O2: o2_c
L-Kynurenine + Glyoxylate ⇄ 4-(2-Aminophenyl)-2,4-dioxobutanoate + Glycine (2.6.1.63)
Glyoxylate: glx_c
L-Formylkynurenine + H2O ⇄ Formate + L-Kynurenine (3.5.1.9)
H2O: h2o_c
L-Tryptophan + O2 ⇄ L-Formylkynurenine (1.13.11.11)
L-Tryptophan: trp__L_c, O2: o2_c
S-Adenosyl-L-methionine + Carnosine ⇄ S-Adenosyl-L-homocysteine + beta-Alanyl-N(pi)-methyl-L-histidine (2.1.1.22)
S-Adenosyl-L-methionine: amet_c
ATP + L-Histidine + beta-Alanine ⇄ ADP + Orthophosphate + Carnosine (6.3.2.11)
ATP: atp_c, L-Histidine: his__L_c, beta-Alanine: ala_B_c
S-Adenosyl-L-methionine + Carnosine ⇄ S-Adenosyl-L-homocysteine + beta-Alanyl-N(pi)-methyl-L-histidine (2.1.1.22)
S-Adenosyl-L-methionine: amet_c
ATP + L-Histidine + beta-Alanine ⇄ ADP + Orthophosphate + Carnosine (6.3.2.11)
ATP: atp_c, L-Histidine: his__L_c, beta-Alanine: ala_B_c
L-Histidinol phosphate + 2-Oxoglutarate ⇄ 3-(Imidazol-4-yl)-2-oxopropyl phosphate + L-Glutamate (2.6.1.9)
2-Oxoglutarate: akg_c, L-Histidinol phosphate: hisp_c
L-Histidinol phosphate + 2-Oxoglutarate ⇄ 3-(Imidazol-4-yl)-2-oxopropyl phosphate + L-Glutamate (2.6.1.9)
2-Oxoglutarate: akg_c, L-Histidinol phosphate: hisp_c
S-Adenosyl-L-methionine + Phenol ⇄ S-Adenosyl-L-homocysteine + Anisole (2.1.1.25)
S-Adenosyl-L-methionine: amet_c
Catechol + NADP+ + H2O ⇄ Phenol + O2 + NADPH + H+ (1.14.13.7)
NADP+: nadp_c, H2O: h2o_c
2-Hydroxymuconate semialdehyde ⇄ Catechol + O2 (1.13.11.2)
2-Hydroxy-2,4-pentadienoate + Formate ⇄ 2-Hydroxymuconate semialdehyde + H2O (3.7.1.9)
Formate: for_c
2-Hydroxy-6-ketononatrienedioate + H2O ⇄ 2-Hydroxy-2,4-pentadienoate + Fumarate (3.7.1.14)
2-Hydroxy-6-ketononatrienedioate: hkntd_c, H2O: h2o_c
2-Hydroxy-6-oxonona-2,4-diene-1,9-dioate + H2O ⇄ 2-Hydroxy-2,4-pentadienoate + Succinate (3.7.1.14)
2-Hydroxy-6-oxonona-2,4-diene-1,9-dioate: hkndd_c, H2O: h2o_c
S-Adenosyl-L-methionine + Phenol ⇄ S-Adenosyl-L-homocysteine + Anisole (2.1.1.25)
S-Adenosyl-L-methionine: amet_c
Catechol + NADP+ + H2O ⇄ Phenol + O2 + NADPH + H+ (1.14.13.7)
NADP+: nadp_c, H2O: h2o_c
2-Hydroxymuconate semialdehyde ⇄ Catechol + O2 (1.13.11.2)
2-Hydroxy-2,4-pentadienoate + Formate ⇄ 2-Hydroxymuconate semialdehyde + H2O (3.7.1.9)
Formate: for_c
2-Hydroxy-6-ketononatrienedioate + H2O ⇄ 2-Hydroxy-2,4-pentadienoate + Fumarate (3.7.1.14)
2-Hydroxy-6-ketononatrienedioate: hkntd_c, H2O: h2o_c
2-Hydroxy-6-oxonona-2,4-diene-1,9-dioate + H2O ⇄ 2-Hydroxy-2,4-pentadienoate + Succinate (3.7.1.14)
2-Hydroxy-6-oxonona-2,4-diene-1,9-dioate: hkndd_c, H2O: h2o_c
6'-Dehydro-6'-oxoparomamine + L-Glutamate ⇄ Neamine + 2-Oxoglutarate (2.6.1.93)
L-Glutamate: glu__L_c
Paromamine + O2 ⇄ 6'-Dehydro-6'-oxoparomamine + Hydrogen peroxide (1.1.3.43)
O2: o2_c
2'-N-Acetylparomamine + H2O ⇄ Paromamine + Acetate (3.5.1.112)
H2O: h2o_c
UDP-N-acetyl-alpha-D-glucosamine + 2-Deoxystreptamine ⇄ UDP + 2'-N-Acetylparomamine (2.4.1.283)
UDP-N-acetyl-alpha-D-glucosamine: uacgam_c
3-Amino-2,3-dideoxy-scyllo-inosose + L-Glutamine ⇄ 2-Deoxystreptamine + 2-Oxoglutaramate (2.6.1.101)
L-Glutamine: gln__L_c
2-Deoxy-scyllo-inosamine + S-Adenosyl-L-methionine ⇄ 3-Amino-2,3-dideoxy-scyllo-inosose + L-Methionine + 5'-Deoxyadenosine (1.1.99.38)
S-Adenosyl-L-methionine: amet_c
2-Deoxy-scyllo-inosose + L-Glutamine ⇄ 2-Deoxy-scyllo-inosamine + 2-Oxoglutaramate (2.6.1.100)
L-Glutamine: gln__L_c
D-Glucose 6-phosphate ⇄ 2-Deoxy-scyllo-inosose + Orthophosphate (4.2.3.124)
D-Glucose 6-phosphate: g6p_c
6'-Dehydro-6'-oxoparomamine + L-Glutamate ⇄ Neamine + 2-Oxoglutarate (2.6.1.93)
L-Glutamate: glu__L_c
Paromamine + O2 ⇄ 6'-Dehydro-6'-oxoparomamine + Hydrogen peroxide (1.1.3.43)
O2: o2_c
2'-N-Acetylparomamine + H2O ⇄ Paromamine + Acetate (3.5.1.112)
H2O: h2o_c
UDP-N-acetyl-alpha-D-glucosamine + 2-Deoxystreptamine ⇄ UDP + 2'-N-Acetylparomamine (2.4.1.283)
UDP-N-acetyl-alpha-D-glucosamine: uacgam_c
3-Amino-2,3-dideoxy-scyllo-inosose + L-Glutamine ⇄ 2-Deoxystreptamine + 2-Oxoglutaramate (2.6.1.101)
L-Glutamine: gln__L_c
2-Deoxy-scyllo-inosamine + S-Adenosyl-L-methionine ⇄ 3-Amino-2,3-dideoxy-scyllo-inosose + L-Methionine + 5'-Deoxyadenosine (1.1.99.38)
S-Adenosyl-L-methionine: amet_c
2-Deoxy-scyllo-inosose + L-Glutamine ⇄ 2-Deoxy-scyllo-inosamine + 2-Oxoglutaramate (2.6.1.100)
L-Glutamine: gln__L_c
D-Glucose 6-phosphate ⇄ 2-Deoxy-scyllo-inosose + Orthophosphate (4.2.3.124)
D-Glucose 6-phosphate: g6p_c
S-Adenosyl-L-methionine + Caffeate ⇄ S-Adenosyl-L-homocysteine + Ferulate (2.1.1.68)
S-Adenosyl-L-methionine: amet_c
3,4-Dihydroxyphenylpropanoate + Caffeoyl-CoA ⇄ Dihydrocaffeoyl-CoA + Caffeate (2.8.3.23)
3,4-Dihydroxy-L-phenylalanine + NADH + H+ ⇄ 3,4-Dihydroxyphenylpropanoate + NAD+ + Ammonia (4.3.1.22)
NADH: nadh_c, H+: h_c
L-Tyrosine + Hydrogen peroxide ⇄ 3,4-Dihydroxy-L-phenylalanine + H2O (1.11.2.6)
L-Tyrosine: tyr__L_c, Hydrogen peroxide: h2o2_c
S-Adenosyl-L-homocysteine + Feruloyl-CoA ⇄ S-Adenosyl-L-methionine + Caffeoyl-CoA (2.1.1.104)
S-Adenosyl-L-homocysteine: ahcys_c
4-Hydroxy-3-methoxy-benzaldehyde + Acetyl-CoA ⇄ Feruloyl-CoA + H2O (4.1.2.61)
Acetyl-CoA: accoa_c
Vanillate + NADH + H+ ⇄ 4-Hydroxy-3-methoxy-benzaldehyde + NAD+ + H2O (1.2.1.67)
NADH: nadh_c, H+: h_c
3,4-Dihydroxybenzoate + NAD+ + H2O + Formaldehyde ⇄ Vanillate + O2 + NADH + H+ (1.14.13.82)
NAD+: nad_c, H2O: h2o_c, Formaldehyde: fald_c
4-Hydroxybenzoate + O2 + NADPH + H+ ⇄ 3,4-Dihydroxybenzoate + NADP+ + H2O (1.14.13.2)
4-Hydroxybenzoate: 4hbz_c, O2: o2_c, NADPH: nadph_c, H+: h_c
4-Hydroxy-3-methoxyphenyl-beta-hydroxypropanoyl-CoA ⇄ Feruloyl-CoA + H2O (4.1.2.61)
4-Hydroxy-3-methoxy-benzaldehyde + Acetyl-CoA ⇄ 4-Hydroxy-3-methoxyphenyl-beta-hydroxypropanoyl-CoA (4.1.2.61)
Acetyl-CoA: accoa_c
Vanillate + NADH + H+ ⇄ 4-Hydroxy-3-methoxy-benzaldehyde + NAD+ + H2O (1.2.1.67)
NADH: nadh_c, H+: h_c
3,4-Dihydroxybenzoate + NAD+ + H2O + Formaldehyde ⇄ Vanillate + O2 + NADH + H+ (1.14.13.82)
NAD+: nad_c, H2O: h2o_c, Formaldehyde: fald_c
4-Hydroxybenzoate + O2 + NADPH + H+ ⇄ 3,4-Dihydroxybenzoate + NADP+ + H2O (1.14.13.2)
4-Hydroxybenzoate: 4hbz_c, O2: o2_c, NADPH: nadph_c, H+: h_c
S-Adenosyl-L-methionine + Caffeate ⇄ S-Adenosyl-L-homocysteine + Ferulate (2.1.1.68)
S-Adenosyl-L-methionine: amet_c
3,4-Dihydroxyphenylpropanoate + Caffeoyl-CoA ⇄ Dihydrocaffeoyl-CoA + Caffeate (2.8.3.23)
3,4-Dihydroxy-L-phenylalanine + NADH + H+ ⇄ 3,4-Dihydroxyphenylpropanoate + NAD+ + Ammonia (4.3.1.22)
NADH: nadh_c, H+: h_c
L-Tyrosine + Hydrogen peroxide ⇄ 3,4-Dihydroxy-L-phenylalanine + H2O (1.11.2.6)
L-Tyrosine: tyr__L_c, Hydrogen peroxide: h2o2_c
S-Adenosyl-L-homocysteine + Feruloyl-CoA ⇄ S-Adenosyl-L-methionine + Caffeoyl-CoA (2.1.1.104)
S-Adenosyl-L-homocysteine: ahcys_c
4-Hydroxy-3-methoxy-benzaldehyde + Acetyl-CoA ⇄ Feruloyl-CoA + H2O (4.1.2.61)
Acetyl-CoA: accoa_c
Vanillate + NADH + H+ ⇄ 4-Hydroxy-3-methoxy-benzaldehyde + NAD+ + H2O (1.2.1.67)
NADH: nadh_c, H+: h_c
3,4-Dihydroxybenzoate + NAD+ + H2O + Formaldehyde ⇄ Vanillate + O2 + NADH + H+ (1.14.13.82)
NAD+: nad_c, H2O: h2o_c, Formaldehyde: fald_c
4-Hydroxybenzoate + O2 + NADPH + H+ ⇄ 3,4-Dihydroxybenzoate + NADP+ + H2O (1.14.13.2)
4-Hydroxybenzoate: 4hbz_c, O2: o2_c, NADPH: nadph_c, H+: h_c
4-Hydroxy-3-methoxyphenyl-beta-hydroxypropanoyl-CoA ⇄ Feruloyl-CoA + H2O (4.1.2.61)
4-Hydroxy-3-methoxy-benzaldehyde + Acetyl-CoA ⇄ 4-Hydroxy-3-methoxyphenyl-beta-hydroxypropanoyl-CoA (4.1.2.61)
Acetyl-CoA: accoa_c
Vanillate + NADH + H+ ⇄ 4-Hydroxy-3-methoxy-benzaldehyde + NAD+ + H2O (1.2.1.67)
NADH: nadh_c, H+: h_c
3,4-Dihydroxybenzoate + NAD+ + H2O + Formaldehyde ⇄ Vanillate + O2 + NADH + H+ (1.14.13.82)
NAD+: nad_c, H2O: h2o_c, Formaldehyde: fald_c
4-Hydroxybenzoate + O2 + NADPH + H+ ⇄ 3,4-Dihydroxybenzoate + NADP+ + H2O (1.14.13.2)
4-Hydroxybenzoate: 4hbz_c, O2: o2_c, NADPH: nadph_c, H+: h_c
5-Amino-2-oxopentanoic acid + L-Glutamate ⇄ Ornithine + 2-Oxoglutarate (2.6.1.8)
L-Glutamate: glu__L_c
Ornithine + 2-Oxoglutarate ⇄ 5-Amino-2-oxopentanoic acid + L-Glutamate (2.6.1.8)
Ornithine: orn_c, 2-Oxoglutarate: akg_c
5-Amino-2-oxopentanoic acid + L-Glutamate ⇄ Ornithine + 2-Oxoglutarate (2.6.1.8)
L-Glutamate: glu__L_c
Ornithine + 2-Oxoglutarate ⇄ 5-Amino-2-oxopentanoic acid + L-Glutamate (2.6.1.8)
Ornithine: orn_c, 2-Oxoglutarate: akg_c
L-Kynurenine + 2-Oxoglutarate ⇄ 4-Hydroxy-2-quinolinecarboxylic acid + L-Glutamate + H2O (2.6.1.7)
2-Oxoglutarate: akg_c
L-Formylkynurenine + H2O ⇄ Formate + L-Kynurenine (3.5.1.9)
H2O: h2o_c
L-Tryptophan + O2 ⇄ L-Formylkynurenine (1.13.11.11)
L-Tryptophan: trp__L_c, O2: o2_c
L-Kynurenine + Glyoxylate ⇄ 4-Hydroxy-2-quinolinecarboxylic acid + Glycine + H2O (2.6.1.63)
Glyoxylate: glx_c
L-Formylkynurenine + H2O ⇄ Formate + L-Kynurenine (3.5.1.9)
H2O: h2o_c
L-Tryptophan + O2 ⇄ L-Formylkynurenine (1.13.11.11)
L-Tryptophan: trp__L_c, O2: o2_c
L-Kynurenine + 2-Oxoglutarate ⇄ 4-Hydroxy-2-quinolinecarboxylic acid + L-Glutamate + H2O (2.6.1.7)
2-Oxoglutarate: akg_c
L-Formylkynurenine + H2O ⇄ Formate + L-Kynurenine (3.5.1.9)
H2O: h2o_c
L-Tryptophan + O2 ⇄ L-Formylkynurenine (1.13.11.11)
L-Tryptophan: trp__L_c, O2: o2_c
L-Kynurenine + Glyoxylate ⇄ 4-Hydroxy-2-quinolinecarboxylic acid + Glycine + H2O (2.6.1.63)
Glyoxylate: glx_c
L-Formylkynurenine + H2O ⇄ Formate + L-Kynurenine (3.5.1.9)
H2O: h2o_c
L-Tryptophan + O2 ⇄ L-Formylkynurenine (1.13.11.11)
L-Tryptophan: trp__L_c, O2: o2_c
Glycine + Oxalureate ⇄ (S)-Ureidoglycine + Glyoxylate (2.6.1.112)
Glycine: gly_c, Oxalureate: oxur_c
Glycine + Oxalureate ⇄ (S)-Ureidoglycine + Glyoxylate (2.6.1.112)
Glycine: gly_c, Oxalureate: oxur_c
S-Adenosyl-L-methionine + Tyramine ⇄ S-Adenosyl-L-homocysteine + N-Methyltyramine (2.1.1.27)
S-Adenosyl-L-methionine: amet_c, Tyramine: tym_p
S-Adenosyl-L-methionine + Tyramine ⇄ S-Adenosyl-L-homocysteine + N-Methyltyramine (2.1.1.27)
S-Adenosyl-L-methionine: amet_c, Tyramine: tym_p
2 S-Adenosyl-L-methionine + Uroporphyrinogen III ⇄ 2 S-Adenosyl-L-homocysteine + Precorrin 2 (2.1.1.107)
S-Adenosyl-L-methionine: amet_c, Uroporphyrinogen III: uppg3_c
S-Adenosyl-L-methionine + Precorrin 1 ⇄ S-Adenosyl-L-homocysteine + Precorrin 2 (2.1.1.107)
S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + Uroporphyrinogen III ⇄ S-Adenosyl-L-homocysteine + Precorrin 1 (2.1.1.107)
S-Adenosyl-L-methionine: amet_c, Uroporphyrinogen III: uppg3_c
S-Adenosyl-L-homocysteine + Precorrin 2 ⇄ S-Adenosyl-L-methionine + Precorrin 1 (2.1.1.107)
S-Adenosyl-L-homocysteine: ahcys_c, Precorrin 2: dscl_c
2 S-Adenosyl-L-methionine + Uroporphyrinogen III ⇄ 2 S-Adenosyl-L-homocysteine + Precorrin 2 (2.1.1.107)
S-Adenosyl-L-methionine: amet_c, Uroporphyrinogen III: uppg3_c
S-Adenosyl-L-methionine + Precorrin 1 ⇄ S-Adenosyl-L-homocysteine + Precorrin 2 (2.1.1.107)
S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + Uroporphyrinogen III ⇄ S-Adenosyl-L-homocysteine + Precorrin 1 (2.1.1.107)
S-Adenosyl-L-methionine: amet_c, Uroporphyrinogen III: uppg3_c
S-Adenosyl-L-homocysteine + Precorrin 2 ⇄ S-Adenosyl-L-methionine + Precorrin 1 (2.1.1.107)
S-Adenosyl-L-homocysteine: ahcys_c, Precorrin 2: dscl_c
3-Hydroxy-L-kynurenine + Glyoxylate ⇄ Xanthurenic acid + Glycine + H2O (2.6.1.63)
Glyoxylate: glx_c
L-Kynurenine + O2 + NADPH + H+ ⇄ 3-Hydroxy-L-kynurenine + NADP+ + H2O (1.14.13.9)
O2: o2_c, NADPH: nadph_c, H+: h_c
L-Formylkynurenine + H2O ⇄ Formate + L-Kynurenine (3.5.1.9)
H2O: h2o_c
L-Tryptophan + O2 ⇄ L-Formylkynurenine (1.13.11.11)
L-Tryptophan: trp__L_c, O2: o2_c
3-Hydroxy-L-kynurenine + Glyoxylate ⇄ Xanthurenic acid + Glycine + H2O (2.6.1.63)
Glyoxylate: glx_c
L-Kynurenine + O2 + NADPH + H+ ⇄ 3-Hydroxy-L-kynurenine + NADP+ + H2O (1.14.13.9)
O2: o2_c, NADPH: nadph_c, H+: h_c
L-Formylkynurenine + H2O ⇄ Formate + L-Kynurenine (3.5.1.9)
H2O: h2o_c
L-Tryptophan + O2 ⇄ L-Formylkynurenine (1.13.11.11)
L-Tryptophan: trp__L_c, O2: o2_c
S-Adenosyl-L-methionine + gamma-Tocopherol ⇄ S-Adenosyl-L-homocysteine + alpha-Tocopherol (2.1.1.95)
S-Adenosyl-L-methionine: amet_c
2,3-Dimethyl-5-phytylquinol ⇄ gamma-Tocopherol (5.5.1.24)
2-Methyl-6-phytylquinol + S-Adenosyl-L-methionine ⇄ 2,3-Dimethyl-5-phytylquinol + S-Adenosyl-L-homocysteine (2.1.1.295)
S-Adenosyl-L-methionine: amet_c
Phytyl diphosphate + Homogentisate ⇄ 2-Methyl-6-phytylquinol + Diphosphate + CO2 (2.5.1.115)
Geranylgeranyl diphosphate + 3 H+ + 3 NADPH ⇄ Phytyl diphosphate + 3 NADP+ (1.3.1.83)
H+: h_c, NADPH: nadph_c
trans,trans-Farnesyl diphosphate + Isopentenyl diphosphate ⇄ Diphosphate + Geranylgeranyl diphosphate (2.5.1.29)
trans,trans-Farnesyl diphosphate: frdp_c, Isopentenyl diphosphate: ipdp_c
4-Maleylacetoacetate ⇄ Homogentisate + O2 (1.13.11.5)
4-Fumarylacetoacetate ⇄ 4-Maleylacetoacetate (5.2.1.2)
Acetoacetate + Fumarate ⇄ 4-Fumarylacetoacetate + H2O (3.7.1.2)
Acetoacetate: acac_c, Fumarate: fum_c
S-Adenosyl-L-methionine + gamma-Tocopherol ⇄ S-Adenosyl-L-homocysteine + alpha-Tocopherol (2.1.1.95)
S-Adenosyl-L-methionine: amet_c
2,3-Dimethyl-5-phytylquinol ⇄ gamma-Tocopherol (5.5.1.24)
2-Methyl-6-phytylquinol + S-Adenosyl-L-methionine ⇄ 2,3-Dimethyl-5-phytylquinol + S-Adenosyl-L-homocysteine (2.1.1.295)
S-Adenosyl-L-methionine: amet_c
Phytyl diphosphate + Homogentisate ⇄ 2-Methyl-6-phytylquinol + Diphosphate + CO2 (2.5.1.115)
Geranylgeranyl diphosphate + 3 H+ + 3 NADPH ⇄ Phytyl diphosphate + 3 NADP+ (1.3.1.83)
H+: h_c, NADPH: nadph_c
trans,trans-Farnesyl diphosphate + Isopentenyl diphosphate ⇄ Diphosphate + Geranylgeranyl diphosphate (2.5.1.29)
trans,trans-Farnesyl diphosphate: frdp_c, Isopentenyl diphosphate: ipdp_c
4-Maleylacetoacetate ⇄ Homogentisate + O2 (1.13.11.5)
4-Fumarylacetoacetate ⇄ 4-Maleylacetoacetate (5.2.1.2)
Acetoacetate + Fumarate ⇄ 4-Fumarylacetoacetate + H2O (3.7.1.2)
Acetoacetate: acac_c, Fumarate: fum_c
S-Adenosyl-L-methionine + Putrescine ⇄ S-Adenosyl-L-homocysteine + N-Methylputrescine (2.1.1.53)
S-Adenosyl-L-methionine: amet_c, Putrescine: ptrc_c
S-Adenosyl-L-methionine + Putrescine ⇄ S-Adenosyl-L-homocysteine + N-Methylputrescine (2.1.1.53)
S-Adenosyl-L-methionine: amet_c, Putrescine: ptrc_c
5-Aminolevulinate + Pyruvate ⇄ 4,5-Dioxopentanoate + L-Alanine (2.6.1.43)
Pyruvate: pyr_c, 5-Aminolevulinate: 5aop_c
5-Aminolevulinate + Pyruvate ⇄ 4,5-Dioxopentanoate + L-Alanine (2.6.1.43)
Pyruvate: pyr_c, 5-Aminolevulinate: 5aop_c
S-Adenosyl-L-methionine + Nicotinamide + H+ ⇄ S-Adenosyl-L-homocysteine + 1-Methylnicotinamide (2.1.1.1)
S-Adenosyl-L-methionine: amet_c, Nicotinamide: ncam_c, H+: h_c
S-Adenosyl-L-methionine + Nicotinamide + H+ ⇄ S-Adenosyl-L-homocysteine + 1-Methylnicotinamide (2.1.1.1)
S-Adenosyl-L-methionine: amet_c, Nicotinamide: ncam_c, H+: h_c
S-Adenosyl-L-methionine + Anthranilate ⇄ S-Adenosyl-L-homocysteine + N-Methylanthranilate (2.1.1.111)
S-Adenosyl-L-methionine: amet_c, Anthranilate: anth_c
S-Adenosyl-L-methionine + Anthranilate ⇄ S-Adenosyl-L-homocysteine + N-Methylanthranilate (2.1.1.111)
S-Adenosyl-L-methionine: amet_c, Anthranilate: anth_c
2-Aminoethylphosphonate + Pyruvate ⇄ Phosphonoacetaldehyde + L-Alanine (2.6.1.37)
Pyruvate: pyr_c
(2-Amino-1-hydroxyethyl)phosphonate + Succinate + CO2 ⇄ 2-Aminoethylphosphonate + 2-Oxoglutarate + O2 (1.14.11.46)
Succinate: succ_c, CO2: co2_c
Glycine + Orthophosphate ⇄ (2-Amino-1-hydroxyethyl)phosphonate + O2 (1.13.11.78)
Glycine: gly_c, Orthophosphate: pi_c
2-Aminoethylphosphonate + Pyruvate ⇄ Phosphonoacetaldehyde + L-Alanine (2.6.1.37)
Pyruvate: pyr_c
(2-Amino-1-hydroxyethyl)phosphonate + Succinate + CO2 ⇄ 2-Aminoethylphosphonate + 2-Oxoglutarate + O2 (1.14.11.46)
Succinate: succ_c, CO2: co2_c
Glycine + Orthophosphate ⇄ (2-Amino-1-hydroxyethyl)phosphonate + O2 (1.13.11.78)
Glycine: gly_c, Orthophosphate: pi_c
S-Adenosyl-L-methionine + L-Methionine ⇄ S-Adenosyl-L-homocysteine + S-Methyl-L-methionine (2.1.1.12)
S-Adenosyl-L-methionine: amet_c, L-Methionine: met__L_c
S-Adenosyl-L-methionine + L-Methionine ⇄ S-Adenosyl-L-homocysteine + S-Methyl-L-methionine (2.1.1.12)
S-Adenosyl-L-methionine: amet_c, L-Methionine: met__L_c
O-Phospho-L-serine + 2-Oxoglutarate ⇄ 3-Phosphonooxypyruvate + L-Glutamate (2.6.1.52)
2-Oxoglutarate: akg_c, O-Phospho-L-serine: pser__L_c
O-Phospho-L-serine + 2-Oxoglutarate ⇄ 3-Phosphonooxypyruvate + L-Glutamate (2.6.1.52)
2-Oxoglutarate: akg_c, O-Phospho-L-serine: pser__L_c
5-Aminopentanoate + 2-Oxoglutarate ⇄ 5-Oxopentanoate + L-Glutamate (2.6.1.48)
2-Oxoglutarate: akg_c
5-Aminopentanamide + H2O ⇄ 5-Aminopentanoate + Ammonia (3.5.1.30)
H2O: h2o_c
L-Lysine + O2 ⇄ 5-Aminopentanamide + CO2 + H2O (1.13.12.2)
L-Lysine: lys__L_c, O2: o2_c
5-Aminopentanoate + 2-Oxoglutarate ⇄ 5-Oxopentanoate + L-Glutamate (2.6.1.48)
2-Oxoglutarate: akg_c
5-Aminopentanamide + H2O ⇄ 5-Aminopentanoate + Ammonia (3.5.1.30)
H2O: h2o_c
L-Lysine + O2 ⇄ 5-Aminopentanamide + CO2 + H2O (1.13.12.2)
L-Lysine: lys__L_c, O2: o2_c
L-Histidine + 2-Oxoglutarate ⇄ Imidazol-5-yl-pyruvate + L-Glutamate (2.6.1.38)
2-Oxoglutarate: akg_c, L-Histidine: his__L_c
L-Histidine + 2-Oxoglutarate ⇄ Imidazol-5-yl-pyruvate + L-Glutamate (2.6.1.38)
2-Oxoglutarate: akg_c, L-Histidine: his__L_c
S-Adenosyl-L-methionine + L-Histidine ⇄ S-Adenosyl-L-homocysteine + Nalpha-Methylhistidine (2.1.1.44)
S-Adenosyl-L-methionine: amet_c, L-Histidine: his__L_c
S-Adenosyl-L-methionine + L-Histidine ⇄ S-Adenosyl-L-homocysteine + Nalpha-Methylhistidine (2.1.1.44)
S-Adenosyl-L-methionine: amet_c, L-Histidine: his__L_c
S-Adenosyl-L-methionine + Fatty acid ⇄ S-Adenosyl-L-homocysteine + Fatty acid methyl ester (2.1.1.15)
S-Adenosyl-L-methionine: amet_c
ADP + Acyl phosphate ⇄ ATP + Fatty acid (2.7.2.18)
ADP: adp_c
Acyl-[acyl-carrier protein] + Orthophosphate ⇄ Acyl phosphate + Acyl-carrier protein (2.3.1.274)
Orthophosphate: pi_c
trans-2,3-Dehydroacyl-[acyl-carrier protein] + NADH + H+ ⇄ Acyl-[acyl-carrier protein] + NAD+ (1.3.1.9)
NADH: nadh_c, H+: h_c
(3R)-3-Hydroxyacyl-[acyl-carrier protein] ⇄ trans-2,3-Dehydroacyl-[acyl-carrier protein] + H2O (4.2.1.59)
(3R)-3-Hydroxyacyl-[acyl-carrier protein]: 3haACP_c
S-Adenosyl-L-methionine + Fatty acid ⇄ S-Adenosyl-L-homocysteine + Fatty acid methyl ester (2.1.1.15)
S-Adenosyl-L-methionine: amet_c
ADP + Acyl phosphate ⇄ ATP + Fatty acid (2.7.2.18)
ADP: adp_c
Acyl-[acyl-carrier protein] + Orthophosphate ⇄ Acyl phosphate + Acyl-carrier protein (2.3.1.274)
Orthophosphate: pi_c
trans-2,3-Dehydroacyl-[acyl-carrier protein] + NADH + H+ ⇄ Acyl-[acyl-carrier protein] + NAD+ (1.3.1.9)
NADH: nadh_c, H+: h_c
(3R)-3-Hydroxyacyl-[acyl-carrier protein] ⇄ trans-2,3-Dehydroacyl-[acyl-carrier protein] + H2O (4.2.1.59)
(3R)-3-Hydroxyacyl-[acyl-carrier protein]: 3haACP_c
N-Succinyl-L-glutamate 5-semialdehyde + L-Glutamate ⇄ N2-Succinyl-L-ornithine + 2-Oxoglutarate (2.6.1.81)
L-Glutamate: glu__L_c, N-Succinyl-L-glutamate 5-semialdehyde: sucgsa_c
N-Succinyl-L-glutamate 5-semialdehyde + L-Glutamate ⇄ N2-Succinyl-L-ornithine + 2-Oxoglutarate (2.6.1.81)
L-Glutamate: glu__L_c, N-Succinyl-L-glutamate 5-semialdehyde: sucgsa_c
4-Hydroxyphenylglyoxylate + L-Glutamate ⇄ D-4-Hydroxyphenylglycine + 2-Oxoglutarate (2.6.1.72)
L-Glutamate: glu__L_c
(S)-4-Hydroxymandelate + O2 ⇄ 4-Hydroxyphenylglyoxylate + Hydrogen peroxide (1.1.3.46)
O2: o2_c
4-Hydroxybenzaldehyde + Hydrogen peroxide + CO2 ⇄ (S)-4-Hydroxymandelate + O2 (1.1.3.19)
Hydrogen peroxide: h2o2_c, CO2: co2_c
4-Hydroxybenzoate + NADH + H+ ⇄ 4-Hydroxybenzaldehyde + NAD+ + H2O (1.2.1.64)
4-Hydroxybenzoate: 4hbz_c, NADH: nadh_c, H+: h_c
4-Hydroxyphenylglyoxylate + L-Glutamate ⇄ D-4-Hydroxyphenylglycine + 2-Oxoglutarate (2.6.1.72)
L-Glutamate: glu__L_c
(S)-4-Hydroxymandelate + O2 ⇄ 4-Hydroxyphenylglyoxylate + Hydrogen peroxide (1.1.3.46)
O2: o2_c
4-Hydroxybenzaldehyde + Hydrogen peroxide + CO2 ⇄ (S)-4-Hydroxymandelate + O2 (1.1.3.19)
Hydrogen peroxide: h2o2_c, CO2: co2_c
4-Hydroxybenzoate + NADH + H+ ⇄ 4-Hydroxybenzaldehyde + NAD+ + H2O (1.2.1.64)
4-Hydroxybenzoate: 4hbz_c, NADH: nadh_c, H+: h_c
5,10-Methylenetetrahydrofolate + dCMP ⇄ Dihydrofolate + Deoxy-5-methylcytidylate (2.1.1.54)
5,10-Methylenetetrahydrofolate: mlthf_c, dCMP: dcmp_c
5,10-Methylenetetrahydrofolate + dCMP ⇄ Dihydrofolate + Deoxy-5-methylcytidylate (2.1.1.54)
5,10-Methylenetetrahydrofolate: mlthf_c, dCMP: dcmp_c
Phosphonoacetaldehyde + L-Alanine ⇄ 2-Aminoethylphosphonate + Pyruvate (2.6.1.37)
L-Alanine: ala__L_c
2-Hydroxyethylphosphonate + NAD+ ⇄ Phosphonoacetaldehyde + NADH + H+ (1.1.1.309)
NAD+: nad_c
Hydroxymethylphosphonate + Formate ⇄ 2-Hydroxyethylphosphonate + O2 (1.13.11.72)
Formate: for_c
Formate + Orthophosphate ⇄ Hydroxymethylphosphonate + O2 (1.13.11.89)
Formate: for_c, Orthophosphate: pi_c
Phosphonoacetaldehyde + L-Alanine ⇄ 2-Aminoethylphosphonate + Pyruvate (2.6.1.37)
L-Alanine: ala__L_c
2-Hydroxyethylphosphonate + NAD+ ⇄ Phosphonoacetaldehyde + NADH + H+ (1.1.1.309)
NAD+: nad_c
Hydroxymethylphosphonate + Formate ⇄ 2-Hydroxyethylphosphonate + O2 (1.13.11.72)
Formate: for_c
Formate + Orthophosphate ⇄ Hydroxymethylphosphonate + O2 (1.13.11.89)
Formate: for_c, Orthophosphate: pi_c
S-Adenosyl-L-methionine + myo-Inositol ⇄ S-Adenosyl-L-homocysteine + D-Bornesitol (2.1.1.40)
S-Adenosyl-L-methionine: amet_c, myo-Inositol: inost_c
S-Adenosyl-L-methionine + myo-Inositol ⇄ S-Adenosyl-L-homocysteine + D-Bornesitol (2.1.1.40)
S-Adenosyl-L-methionine: amet_c, myo-Inositol: inost_c
S-Adenosyl-L-methionine + myo-Inositol ⇄ S-Adenosyl-L-homocysteine + L-Bornesitol (2.1.1.39)
S-Adenosyl-L-methionine: amet_c, myo-Inositol: inost_c
S-Adenosyl-L-methionine + myo-Inositol ⇄ S-Adenosyl-L-homocysteine + L-Bornesitol (2.1.1.39)
S-Adenosyl-L-methionine: amet_c, myo-Inositol: inost_c
S-Adenosyl-L-methionine + L-Arginine ⇄ S-Adenosyl-L-homocysteine + N(omega)-Methyl-L-arginine (2.1.1.381)
S-Adenosyl-L-methionine: amet_c, L-Arginine: arg__L_c
S-Adenosyl-L-methionine + L-Arginine ⇄ S-Adenosyl-L-homocysteine + N(omega)-Methyl-L-arginine (2.1.1.381)
S-Adenosyl-L-methionine: amet_c, L-Arginine: arg__L_c
LL-2,6-Diaminoheptanedioate + 2-Oxoglutarate ⇄ 2,3,4,5-Tetrahydrodipicolinate + L-Glutamate + H2O (2.6.1.83)
2-Oxoglutarate: akg_c, LL-2,6-Diaminoheptanedioate: 26dap_LL_c
LL-2,6-Diaminoheptanedioate + 2-Oxoglutarate ⇄ 2,3,4,5-Tetrahydrodipicolinate + L-Glutamate + H2O (2.6.1.83)
2-Oxoglutarate: akg_c, LL-2,6-Diaminoheptanedioate: 26dap_LL_c
S-Adenosyl-L-methionine + 3-Hydroxyanthranilate ⇄ S-Adenosyl-L-homocysteine + 3-Hydroxy-4-methylanthranilate (2.1.1.97)
S-Adenosyl-L-methionine: amet_c
2-Amino-3-carboxymuconate semialdehyde ⇄ 3-Hydroxyanthranilate + O2 (1.13.11.6)
2-Aminomuconate semialdehyde + CO2 ⇄ 2-Amino-3-carboxymuconate semialdehyde (4.1.1.45)
CO2: co2_c
2-Aminomuconate + H+ + NADH ⇄ 2-Aminomuconate semialdehyde + NAD+ + H2O (1.2.1.32)
H+: h_c, NADH: nadh_c
gamma-Oxalocrotonate + Ammonia ⇄ 2-Aminomuconate + H2O (3.5.99.5)
Ammonia: nh4_c
2-Hydroxy-2,4-pentadienoate + CO2 ⇄ gamma-Oxalocrotonate (4.1.1.77)
CO2: co2_c
2-Hydroxy-6-ketononatrienedioate + H2O ⇄ 2-Hydroxy-2,4-pentadienoate + Fumarate (3.7.1.14)
2-Hydroxy-6-ketononatrienedioate: hkntd_c, H2O: h2o_c
2-Hydroxy-6-oxonona-2,4-diene-1,9-dioate + H2O ⇄ 2-Hydroxy-2,4-pentadienoate + Succinate (3.7.1.14)
2-Hydroxy-6-oxonona-2,4-diene-1,9-dioate: hkndd_c, H2O: h2o_c
S-Adenosyl-L-methionine + 3-Hydroxyanthranilate ⇄ S-Adenosyl-L-homocysteine + 3-Hydroxy-4-methylanthranilate (2.1.1.97)
S-Adenosyl-L-methionine: amet_c
2-Amino-3-carboxymuconate semialdehyde ⇄ 3-Hydroxyanthranilate + O2 (1.13.11.6)
2-Aminomuconate semialdehyde + CO2 ⇄ 2-Amino-3-carboxymuconate semialdehyde (4.1.1.45)
CO2: co2_c
2-Aminomuconate + H+ + NADH ⇄ 2-Aminomuconate semialdehyde + NAD+ + H2O (1.2.1.32)
H+: h_c, NADH: nadh_c
gamma-Oxalocrotonate + Ammonia ⇄ 2-Aminomuconate + H2O (3.5.99.5)
Ammonia: nh4_c
2-Hydroxy-2,4-pentadienoate + CO2 ⇄ gamma-Oxalocrotonate (4.1.1.77)
CO2: co2_c
2-Hydroxy-6-ketononatrienedioate + H2O ⇄ 2-Hydroxy-2,4-pentadienoate + Fumarate (3.7.1.14)
2-Hydroxy-6-ketononatrienedioate: hkntd_c, H2O: h2o_c
2-Hydroxy-6-oxonona-2,4-diene-1,9-dioate + H2O ⇄ 2-Hydroxy-2,4-pentadienoate + Succinate (3.7.1.14)
2-Hydroxy-6-oxonona-2,4-diene-1,9-dioate: hkndd_c, H2O: h2o_c
3-(Methylthio)propanoate + 5-Methyltetrahydrofolate ⇄ S,S-Dimethyl-beta-propiothetin + Tetrahydrofolate (2.1.1.269)
5-Methyltetrahydrofolate: 5mthf_c
1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one + O2 ⇄ 3-(Methylthio)propanoate + Formate + CO (1.13.11.53)
O2: o2_c
4-Methylthio-2-oxobutanoic acid + Formate ⇄ 1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one + O2 (1.13.11.54)
Formate: for_c
D-Methionine + Pyruvate ⇄ 4-Methylthio-2-oxobutanoic acid + L-Alanine (2.6.1.41)
D-Methionine: met__D_c, Pyruvate: pyr_c
3-(Methylthio)propanoate + 5-Methyltetrahydrofolate ⇄ S,S-Dimethyl-beta-propiothetin + Tetrahydrofolate (2.1.1.269)
5-Methyltetrahydrofolate: 5mthf_c
1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one + O2 ⇄ 3-(Methylthio)propanoate + Formate + CO (1.13.11.53)
O2: o2_c
4-Methylthio-2-oxobutanoic acid + Formate ⇄ 1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one + O2 (1.13.11.54)
Formate: for_c
D-Methionine + Pyruvate ⇄ 4-Methylthio-2-oxobutanoic acid + L-Alanine (2.6.1.41)
D-Methionine: met__D_c, Pyruvate: pyr_c
3,4-Dihydroxy-L-phenylalanine + 2-Oxoglutarate ⇄ 3-(3,4-Dihydroxyphenyl)pyruvate + L-Glutamate (2.6.1.49)
2-Oxoglutarate: akg_c
L-Tyrosine + Hydrogen peroxide ⇄ 3,4-Dihydroxy-L-phenylalanine + H2O (1.11.2.6)
L-Tyrosine: tyr__L_c, Hydrogen peroxide: h2o2_c
3,4-Dihydroxy-L-phenylalanine + 2-Oxoglutarate ⇄ 3-(3,4-Dihydroxyphenyl)pyruvate + L-Glutamate (2.6.1.49)
2-Oxoglutarate: akg_c
L-Tyrosine + Hydrogen peroxide ⇄ 3,4-Dihydroxy-L-phenylalanine + H2O (1.11.2.6)
L-Tyrosine: tyr__L_c, Hydrogen peroxide: h2o2_c
L-Lysine + 2-Oxoglutarate ⇄ L-2-Aminoadipate 6-semialdehyde + L-Glutamate (2.6.1.36)
2-Oxoglutarate: akg_c, L-Lysine: lys__L_c
L-Lysine + Pyruvate ⇄ L-2-Aminoadipate 6-semialdehyde + L-Alanine (2.6.1.71)
Pyruvate: pyr_c, L-Lysine: lys__L_c
L-Lysine + 2-Oxoglutarate ⇄ L-2-Aminoadipate 6-semialdehyde + L-Glutamate (2.6.1.36)
2-Oxoglutarate: akg_c, L-Lysine: lys__L_c
L-Lysine + Pyruvate ⇄ L-2-Aminoadipate 6-semialdehyde + L-Alanine (2.6.1.71)
Pyruvate: pyr_c, L-Lysine: lys__L_c
S-Adenosyl-L-methionine + Nalpha-Methylhistidine ⇄ S-Adenosyl-L-homocysteine + N,N-Dimethylhistidine (2.1.1.44)
S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + L-Histidine ⇄ S-Adenosyl-L-homocysteine + Nalpha-Methylhistidine (2.1.1.44)
S-Adenosyl-L-methionine: amet_c, L-Histidine: his__L_c
S-Adenosyl-L-methionine + Nalpha-Methylhistidine ⇄ S-Adenosyl-L-homocysteine + N,N-Dimethylhistidine (2.1.1.44)
S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + L-Histidine ⇄ S-Adenosyl-L-homocysteine + Nalpha-Methylhistidine (2.1.1.44)
S-Adenosyl-L-methionine: amet_c, L-Histidine: his__L_c
dTDP-4-oxo-6-deoxy-D-glucose + L-Glutamate ⇄ dTDP-4-amino-4,6-dideoxy-D-glucose + 2-Oxoglutarate (2.6.1.33)
L-Glutamate: glu__L_c, dTDP-4-oxo-6-deoxy-D-glucose: dtdp4d6dg_c
dTDP-4-oxo-6-deoxy-D-glucose + L-Glutamate ⇄ dTDP-4-amino-4,6-dideoxy-D-glucose + 2-Oxoglutarate (2.6.1.33)
L-Glutamate: glu__L_c, dTDP-4-oxo-6-deoxy-D-glucose: dtdp4d6dg_c
S-Adenosyl-L-methionine + Phosphatidyl-N-methylethanolamine ⇄ S-Adenosyl-L-homocysteine + Phosphatidyl-N-dimethylethanolamine (2.1.1.71)
S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + Phosphatidylethanolamine ⇄ S-Adenosyl-L-homocysteine + Phosphatidyl-N-methylethanolamine (2.1.1.17)
S-Adenosyl-L-methionine: amet_c
CDP-ethanolamine + 1,2-Diacyl-sn-glycerol ⇄ CMP + Phosphatidylethanolamine (2.7.8.1)
CTP + Ethanolamine phosphate ⇄ Diphosphate + CDP-ethanolamine (2.7.7.14)
CTP: ctp_c
ATP + Ethanolamine ⇄ ADP + Ethanolamine phosphate (2.7.1.82)
ATP: atp_c, Ethanolamine: etha_c
ADP + Phosphatidate ⇄ ATP + 1,2-Diacyl-sn-glycerol (2.7.1.107)
ADP: adp_c
G00144 + H2O ⇄ 6-(alpha-D-glucosaminyl)-1D-myo-inositol + Phosphatidate (3.1.4.50)
H2O: h2o_c
S-Adenosyl-L-methionine + Phosphatidyl-N-methylethanolamine ⇄ S-Adenosyl-L-homocysteine + Phosphatidyl-N-dimethylethanolamine (2.1.1.71)
S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + Phosphatidylethanolamine ⇄ S-Adenosyl-L-homocysteine + Phosphatidyl-N-methylethanolamine (2.1.1.17)
S-Adenosyl-L-methionine: amet_c
CDP-ethanolamine + 1,2-Diacyl-sn-glycerol ⇄ CMP + Phosphatidylethanolamine (2.7.8.1)
CTP + Ethanolamine phosphate ⇄ Diphosphate + CDP-ethanolamine (2.7.7.14)
CTP: ctp_c
ATP + Ethanolamine ⇄ ADP + Ethanolamine phosphate (2.7.1.82)
ATP: atp_c, Ethanolamine: etha_c
ADP + Phosphatidate ⇄ ATP + 1,2-Diacyl-sn-glycerol (2.7.1.107)
ADP: adp_c
G00144 + H2O ⇄ 6-(alpha-D-glucosaminyl)-1D-myo-inositol + Phosphatidate (3.1.4.50)
H2O: h2o_c
dTDP-4-oxo-6-deoxy-D-glucose + L-Glutamate ⇄ dTDP-4-amino-4,6-dideoxy-D-galactose + 2-Oxoglutarate (2.6.1.59)
L-Glutamate: glu__L_c, dTDP-4-oxo-6-deoxy-D-glucose: dtdp4d6dg_c
dTDP-4-oxo-6-deoxy-D-glucose + L-Glutamate ⇄ dTDP-4-amino-4,6-dideoxy-D-galactose + 2-Oxoglutarate (2.6.1.59)
L-Glutamate: glu__L_c, dTDP-4-oxo-6-deoxy-D-glucose: dtdp4d6dg_c
N-Succinyl-2-L-amino-6-oxoheptanedioate + L-Glutamate ⇄ N-Succinyl-LL-2,6-diaminoheptanedioate + 2-Oxoglutarate (2.6.1.17)
L-Glutamate: glu__L_c, N-Succinyl-2-L-amino-6-oxoheptanedioate: sl2a6o_c
N-Succinyl-2-L-amino-6-oxoheptanedioate + L-Glutamate ⇄ N-Succinyl-LL-2,6-diaminoheptanedioate + 2-Oxoglutarate (2.6.1.17)
L-Glutamate: glu__L_c, N-Succinyl-2-L-amino-6-oxoheptanedioate: sl2a6o_c
Succinyl-CoA + 2,3,4,5-Tetrahydrodipicolinate + H2O ⇄ CoA + N-Succinyl-2-L-amino-6-oxoheptanedioate (2.3.1.117)
Succinyl-CoA: succoa_c, 2,3,4,5-Tetrahydrodipicolinate: thdp_c, H2O: h2o_c
N-Succinyl-LL-2,6-diaminoheptanedioate + 2-Oxoglutarate ⇄ N-Succinyl-2-L-amino-6-oxoheptanedioate + L-Glutamate (2.6.1.17)
2-Oxoglutarate: akg_c, N-Succinyl-LL-2,6-diaminoheptanedioate: sl26da_c
N-Succinyl-LL-2,6-diaminoheptanedioate + 2-Oxoglutarate ⇄ N-Succinyl-2-L-amino-6-oxoheptanedioate + L-Glutamate (2.6.1.17)
2-Oxoglutarate: akg_c, N-Succinyl-LL-2,6-diaminoheptanedioate: sl26da_c
S-Adenosyl-L-methionine + Magnesium protoporphyrin ⇄ S-Adenosyl-L-homocysteine + Magnesium protoporphyrin monomethyl ester (2.1.1.11)
S-Adenosyl-L-methionine: amet_c
ATP + Protoporphyrin + Magnesium cation + H2O ⇄ ADP + Orthophosphate + Magnesium protoporphyrin + 2 H+ (6.6.1.1)
ATP: atp_c, Protoporphyrin: ppp9_c, Magnesium cation: mg2_c, H2O: h2o_c
S-Adenosyl-L-methionine + Magnesium protoporphyrin ⇄ S-Adenosyl-L-homocysteine + Magnesium protoporphyrin monomethyl ester (2.1.1.11)
S-Adenosyl-L-methionine: amet_c
ATP + Protoporphyrin + Magnesium cation + H2O ⇄ ADP + Orthophosphate + Magnesium protoporphyrin + 2 H+ (6.6.1.1)
ATP: atp_c, Protoporphyrin: ppp9_c, Magnesium cation: mg2_c, H2O: h2o_c
Aminoimidazole ribotide + S-Adenosyl-L-methionine ⇄ 4-Amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 5'-Deoxyadenosine + L-Methionine + Formate + CO (4.1.99.17)
S-Adenosyl-L-methionine: amet_c
1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate ⇄ Aminoimidazole ribotide + CO2 (4.1.1.21)
1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate: 5aizc_c
Aminoimidazole ribotide + S-Adenosyl-L-methionine ⇄ 4-Amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 5'-Deoxyadenosine + L-Methionine + Formate + CO (4.1.99.17)
S-Adenosyl-L-methionine: amet_c
1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate ⇄ Aminoimidazole ribotide + CO2 (4.1.1.21)
1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate: 5aizc_c
UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose + L-Glutamate ⇄ UDP-2-acetamido-4-amino-2,4,6-trideoxy-alpha-D-glucose + 2-Oxoglutarate (2.6.1.34)
L-Glutamate: glu__L_c
UDP-N-acetyl-alpha-D-glucosamine ⇄ UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose + H2O (4.2.1.135)
UDP-N-acetyl-alpha-D-glucosamine: uacgam_c
UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose + L-Glutamate ⇄ UDP-2-acetamido-4-amino-2,4,6-trideoxy-alpha-D-glucose + 2-Oxoglutarate (2.6.1.34)
L-Glutamate: glu__L_c
UDP-N-acetyl-alpha-D-glucosamine ⇄ UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose + H2O (4.2.1.135)
UDP-N-acetyl-alpha-D-glucosamine: uacgam_c
Acetoacetyl-CoA + L-Glutamate ⇄ 3-Aminobutanoyl-CoA + 2-Oxoglutarate (2.6.1.111)
L-Glutamate: glu__L_c, Acetoacetyl-CoA: aacoa_c
Acetoacetyl-CoA + L-Glutamate ⇄ 3-Aminobutanoyl-CoA + 2-Oxoglutarate (2.6.1.111)
L-Glutamate: glu__L_c, Acetoacetyl-CoA: aacoa_c
S-Adenosyl-L-methionine + Histamine ⇄ S-Adenosyl-L-homocysteine + N-Methylhistamine (2.1.1.8)
S-Adenosyl-L-methionine: amet_c
L-Histidine ⇄ Histamine + CO2 (4.1.1.22)
L-Histidine: his__L_c
S-Adenosyl-L-methionine + Histamine ⇄ S-Adenosyl-L-homocysteine + N-Methylhistamine (2.1.1.8)
S-Adenosyl-L-methionine: amet_c
L-Histidine ⇄ Histamine + CO2 (4.1.1.22)
L-Histidine: his__L_c
2-Deoxy-scyllo-inosamine + S-Adenosyl-L-methionine ⇄ 3-Amino-2,3-dideoxy-scyllo-inosose + L-Methionine + 5'-Deoxyadenosine (1.1.99.38)
S-Adenosyl-L-methionine: amet_c
2-Deoxy-scyllo-inosose + L-Glutamine ⇄ 2-Deoxy-scyllo-inosamine + 2-Oxoglutaramate (2.6.1.100)
L-Glutamine: gln__L_c
D-Glucose 6-phosphate ⇄ 2-Deoxy-scyllo-inosose + Orthophosphate (4.2.3.124)
D-Glucose 6-phosphate: g6p_c
Magnesium protoporphyrin monomethyl ester + S-Adenosyl-L-methionine + H2O ⇄ 13(1)-Hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + 5'-Deoxyadenosine + L-Methionine (1.21.98.3)
S-Adenosyl-L-methionine: amet_c, H2O: h2o_c
S-Adenosyl-L-methionine + Magnesium protoporphyrin ⇄ S-Adenosyl-L-homocysteine + Magnesium protoporphyrin monomethyl ester (2.1.1.11)
S-Adenosyl-L-methionine: amet_c
ATP + Protoporphyrin + Magnesium cation + H2O ⇄ ADP + Orthophosphate + Magnesium protoporphyrin + 2 H+ (6.6.1.1)
ATP: atp_c, Protoporphyrin: ppp9_c, Magnesium cation: mg2_c, H2O: h2o_c
13(1)-Hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + S-Adenosyl-L-methionine ⇄ 13(1)-Oxo-magnesium-protoporphyrin IX 13-monomethyl ester + 5'-Deoxyadenosine + L-Methionine (1.21.98.3)
S-Adenosyl-L-methionine: amet_c
Magnesium protoporphyrin monomethyl ester + NADPH + H+ + O2 ⇄ 13(1)-Hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O (1.14.13.81)
NADPH: nadph_c, H+: h_c, O2: o2_c
S-Adenosyl-L-methionine + Magnesium protoporphyrin ⇄ S-Adenosyl-L-homocysteine + Magnesium protoporphyrin monomethyl ester (2.1.1.11)
S-Adenosyl-L-methionine: amet_c
ATP + Protoporphyrin + Magnesium cation + H2O ⇄ ADP + Orthophosphate + Magnesium protoporphyrin + 2 H+ (6.6.1.1)
ATP: atp_c, Protoporphyrin: ppp9_c, Magnesium cation: mg2_c, H2O: h2o_c
13(1)-Oxo-magnesium-protoporphyrin IX 13-monomethyl ester + S-Adenosyl-L-methionine ⇄ Divinylprotochlorophyllide + 5'-Deoxyadenosine + L-Methionine (1.21.98.3)
S-Adenosyl-L-methionine: amet_c
13(1)-Hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + O2 ⇄ 13(1)-Oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + 2 H2O (1.14.13.81)
NADPH: nadph_c, H+: h_c, O2: o2_c
Magnesium protoporphyrin monomethyl ester + NADPH + H+ + O2 ⇄ 13(1)-Hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O (1.14.13.81)
NADPH: nadph_c, H+: h_c, O2: o2_c
S-Adenosyl-L-methionine + Magnesium protoporphyrin ⇄ S-Adenosyl-L-homocysteine + Magnesium protoporphyrin monomethyl ester (2.1.1.11)
S-Adenosyl-L-methionine: amet_c
ATP + Protoporphyrin + Magnesium cation + H2O ⇄ ADP + Orthophosphate + Magnesium protoporphyrin + 2 H+ (6.6.1.1)
ATP: atp_c, Protoporphyrin: ppp9_c, Magnesium cation: mg2_c, H2O: h2o_c
Coproporphyrinogen III + 2 S-Adenosyl-L-methionine ⇄ Protoporphyrinogen IX + 2 CO2 + 2 L-Methionine + 2 5'-Deoxyadenosine (1.3.98.3)
S-Adenosyl-L-methionine: amet_c, Coproporphyrinogen III: cpppg3_c
Fe-coproporphyrin III + 2 S-Adenosyl-L-methionine ⇄ Heme + 2 CO2 + 2 5'-Deoxyadenosine + 2 L-Methionine (1.3.98.6)
S-Adenosyl-L-methionine: amet_c
Heme + 2 CO2 + 4 H2O ⇄ Fe-coproporphyrin III + 2 Hydrogen peroxide (1.3.98.5)
Heme: pheme_c, CO2: co2_c, H2O: h2o_c
Harderoheme III + CO2 + 2 H2O ⇄ Fe-coproporphyrin III + Hydrogen peroxide (1.3.98.5)
CO2: co2_c, H2O: h2o_c
Heme + CO2 + 2 H2O ⇄ Harderoheme III + Hydrogen peroxide (1.3.98.5)
Heme: pheme_c, CO2: co2_c, H2O: h2o_c
5-Amino-6-(1-D-ribitylamino)uracil + L-Tyrosine + S-Adenosyl-L-methionine ⇄ 5-Amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + Iminoglycine + L-Methionine + 5'-Deoxyadenosine (2.5.1.147)
S-Adenosyl-L-methionine: amet_c, 5-Amino-6-(1-D-ribitylamino)uracil: 4r5au_c, L-Tyrosine: tyr__L_c
Aminoimidazole ribotide + S-Adenosyl-L-methionine ⇄ 4-Amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 5'-Deoxyadenosine + L-Methionine + Formate + CO (4.1.99.17)
S-Adenosyl-L-methionine: amet_c
1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate ⇄ Aminoimidazole ribotide + CO2 (4.1.1.21)
1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate: 5aizc_c
5-Amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + S-Adenosyl-L-methionine ⇄ 7,8-Didemethyl-8-hydroxy-5-deazariboflavin + Ammonia + L-Methionine + 5'-Deoxyadenosine (4.3.1.32)
S-Adenosyl-L-methionine: amet_c
5-Amino-6-(1-D-ribitylamino)uracil + L-Tyrosine + S-Adenosyl-L-methionine ⇄ 5-Amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + Iminoglycine + L-Methionine + 5'-Deoxyadenosine (2.5.1.147)
5-Amino-6-(1-D-ribitylamino)uracil: 4r5au_c, L-Tyrosine: tyr__L_c, S-Adenosyl-L-methionine: amet_c
2-Deoxy-scyllo-inosamine + S-Adenosyl-L-methionine ⇄ 3-Amino-2,3-dideoxy-scyllo-inosose + L-Methionine + 5'-Deoxyadenosine (1.1.99.38)
S-Adenosyl-L-methionine: amet_c
2-Deoxy-scyllo-inosose + L-Glutamine ⇄ 2-Deoxy-scyllo-inosamine + 2-Oxoglutaramate (2.6.1.100)
L-Glutamine: gln__L_c
D-Glucose 6-phosphate ⇄ 2-Deoxy-scyllo-inosose + Orthophosphate (4.2.3.124)
D-Glucose 6-phosphate: g6p_c
Magnesium protoporphyrin monomethyl ester + S-Adenosyl-L-methionine + H2O ⇄ 13(1)-Hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + 5'-Deoxyadenosine + L-Methionine (1.21.98.3)
S-Adenosyl-L-methionine: amet_c, H2O: h2o_c
S-Adenosyl-L-methionine + Magnesium protoporphyrin ⇄ S-Adenosyl-L-homocysteine + Magnesium protoporphyrin monomethyl ester (2.1.1.11)
S-Adenosyl-L-methionine: amet_c
ATP + Protoporphyrin + Magnesium cation + H2O ⇄ ADP + Orthophosphate + Magnesium protoporphyrin + 2 H+ (6.6.1.1)
ATP: atp_c, Protoporphyrin: ppp9_c, Magnesium cation: mg2_c, H2O: h2o_c
13(1)-Hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + S-Adenosyl-L-methionine ⇄ 13(1)-Oxo-magnesium-protoporphyrin IX 13-monomethyl ester + 5'-Deoxyadenosine + L-Methionine (1.21.98.3)
S-Adenosyl-L-methionine: amet_c
Magnesium protoporphyrin monomethyl ester + NADPH + H+ + O2 ⇄ 13(1)-Hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O (1.14.13.81)
NADPH: nadph_c, H+: h_c, O2: o2_c
S-Adenosyl-L-methionine + Magnesium protoporphyrin ⇄ S-Adenosyl-L-homocysteine + Magnesium protoporphyrin monomethyl ester (2.1.1.11)
S-Adenosyl-L-methionine: amet_c
ATP + Protoporphyrin + Magnesium cation + H2O ⇄ ADP + Orthophosphate + Magnesium protoporphyrin + 2 H+ (6.6.1.1)
ATP: atp_c, Protoporphyrin: ppp9_c, Magnesium cation: mg2_c, H2O: h2o_c
13(1)-Oxo-magnesium-protoporphyrin IX 13-monomethyl ester + S-Adenosyl-L-methionine ⇄ Divinylprotochlorophyllide + 5'-Deoxyadenosine + L-Methionine (1.21.98.3)
S-Adenosyl-L-methionine: amet_c
13(1)-Hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + O2 ⇄ 13(1)-Oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + 2 H2O (1.14.13.81)
NADPH: nadph_c, H+: h_c, O2: o2_c
Magnesium protoporphyrin monomethyl ester + NADPH + H+ + O2 ⇄ 13(1)-Hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O (1.14.13.81)
NADPH: nadph_c, H+: h_c, O2: o2_c
S-Adenosyl-L-methionine + Magnesium protoporphyrin ⇄ S-Adenosyl-L-homocysteine + Magnesium protoporphyrin monomethyl ester (2.1.1.11)
S-Adenosyl-L-methionine: amet_c
ATP + Protoporphyrin + Magnesium cation + H2O ⇄ ADP + Orthophosphate + Magnesium protoporphyrin + 2 H+ (6.6.1.1)
ATP: atp_c, Protoporphyrin: ppp9_c, Magnesium cation: mg2_c, H2O: h2o_c
Coproporphyrinogen III + 2 S-Adenosyl-L-methionine ⇄ Protoporphyrinogen IX + 2 CO2 + 2 L-Methionine + 2 5'-Deoxyadenosine (1.3.98.3)
S-Adenosyl-L-methionine: amet_c, Coproporphyrinogen III: cpppg3_c
Fe-coproporphyrin III + 2 S-Adenosyl-L-methionine ⇄ Heme + 2 CO2 + 2 5'-Deoxyadenosine + 2 L-Methionine (1.3.98.6)
S-Adenosyl-L-methionine: amet_c
Heme + 2 CO2 + 4 H2O ⇄ Fe-coproporphyrin III + 2 Hydrogen peroxide (1.3.98.5)
Heme: pheme_c, CO2: co2_c, H2O: h2o_c
Harderoheme III + CO2 + 2 H2O ⇄ Fe-coproporphyrin III + Hydrogen peroxide (1.3.98.5)
CO2: co2_c, H2O: h2o_c
Heme + CO2 + 2 H2O ⇄ Harderoheme III + Hydrogen peroxide (1.3.98.5)
Heme: pheme_c, CO2: co2_c, H2O: h2o_c
5-Amino-6-(1-D-ribitylamino)uracil + L-Tyrosine + S-Adenosyl-L-methionine ⇄ 5-Amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + Iminoglycine + L-Methionine + 5'-Deoxyadenosine (2.5.1.147)
S-Adenosyl-L-methionine: amet_c, 5-Amino-6-(1-D-ribitylamino)uracil: 4r5au_c, L-Tyrosine: tyr__L_c
Aminoimidazole ribotide + S-Adenosyl-L-methionine ⇄ 4-Amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 5'-Deoxyadenosine + L-Methionine + Formate + CO (4.1.99.17)
S-Adenosyl-L-methionine: amet_c
1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate ⇄ Aminoimidazole ribotide + CO2 (4.1.1.21)
1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate: 5aizc_c
5-Amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + S-Adenosyl-L-methionine ⇄ 7,8-Didemethyl-8-hydroxy-5-deazariboflavin + Ammonia + L-Methionine + 5'-Deoxyadenosine (4.3.1.32)
S-Adenosyl-L-methionine: amet_c
5-Amino-6-(1-D-ribitylamino)uracil + L-Tyrosine + S-Adenosyl-L-methionine ⇄ 5-Amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + Iminoglycine + L-Methionine + 5'-Deoxyadenosine (2.5.1.147)
5-Amino-6-(1-D-ribitylamino)uracil: 4r5au_c, L-Tyrosine: tyr__L_c, S-Adenosyl-L-methionine: amet_c
L-Histidine + 3 S-Adenosyl-L-methionine + H+ ⇄ Hercynine + 3 S-Adenosyl-L-homocysteine (2.1.1.44)
S-Adenosyl-L-methionine: amet_c, L-Histidine: his__L_c, H+: h_c
S-Adenosyl-L-methionine + N,N-Dimethylhistidine ⇄ S-Adenosyl-L-homocysteine + Hercynine (2.1.1.44)
S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + Nalpha-Methylhistidine ⇄ S-Adenosyl-L-homocysteine + N,N-Dimethylhistidine (2.1.1.44)
S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + L-Histidine ⇄ S-Adenosyl-L-homocysteine + Nalpha-Methylhistidine (2.1.1.44)
S-Adenosyl-L-methionine: amet_c, L-Histidine: his__L_c
L-Histidine + 3 S-Adenosyl-L-methionine + H+ ⇄ Hercynine + 3 S-Adenosyl-L-homocysteine (2.1.1.44)
S-Adenosyl-L-methionine: amet_c, L-Histidine: his__L_c, H+: h_c
S-Adenosyl-L-methionine + N,N-Dimethylhistidine ⇄ S-Adenosyl-L-homocysteine + Hercynine (2.1.1.44)
S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + Nalpha-Methylhistidine ⇄ S-Adenosyl-L-homocysteine + N,N-Dimethylhistidine (2.1.1.44)
S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + L-Histidine ⇄ S-Adenosyl-L-homocysteine + Nalpha-Methylhistidine (2.1.1.44)
S-Adenosyl-L-methionine: amet_c, L-Histidine: his__L_c
Gallate + 5-Methyltetrahydrofolate ⇄ 3-O-Methylgallate + Tetrahydrofolate (2.1.1.341)
5-Methyltetrahydrofolate: 5mthf_c
(1E)-4-Oxobut-1-ene-1,2,4-tricarboxylate ⇄ Gallate + O2 (1.13.11.57)
4-Carboxy-4-hydroxy-2-oxoadipate ⇄ (1E)-4-Oxobut-1-ene-1,2,4-tricarboxylate + H2O (4.2.1.83)
Oxaloacetate + Pyruvate ⇄ 4-Carboxy-4-hydroxy-2-oxoadipate (4.1.3.17)
Oxaloacetate: oaa_c, Pyruvate: pyr_c
Gallate + 5-Methyltetrahydrofolate ⇄ 3-O-Methylgallate + Tetrahydrofolate (2.1.1.341)
5-Methyltetrahydrofolate: 5mthf_c
(1E)-4-Oxobut-1-ene-1,2,4-tricarboxylate ⇄ Gallate + O2 (1.13.11.57)
4-Carboxy-4-hydroxy-2-oxoadipate ⇄ (1E)-4-Oxobut-1-ene-1,2,4-tricarboxylate + H2O (4.2.1.83)
Oxaloacetate + Pyruvate ⇄ 4-Carboxy-4-hydroxy-2-oxoadipate (4.1.3.17)
Oxaloacetate: oaa_c, Pyruvate: pyr_c
3-Hydroxy-L-kynurenine + Glyoxylate ⇄ 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate + Glycine (2.6.1.63)
Glyoxylate: glx_c
L-Kynurenine + O2 + NADPH + H+ ⇄ 3-Hydroxy-L-kynurenine + NADP+ + H2O (1.14.13.9)
O2: o2_c, NADPH: nadph_c, H+: h_c
L-Formylkynurenine + H2O ⇄ Formate + L-Kynurenine (3.5.1.9)
H2O: h2o_c
L-Tryptophan + O2 ⇄ L-Formylkynurenine (1.13.11.11)
L-Tryptophan: trp__L_c, O2: o2_c
3-Hydroxy-L-kynurenine + Glyoxylate ⇄ 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate + Glycine (2.6.1.63)
Glyoxylate: glx_c
L-Kynurenine + O2 + NADPH + H+ ⇄ 3-Hydroxy-L-kynurenine + NADP+ + H2O (1.14.13.9)
O2: o2_c, NADPH: nadph_c, H+: h_c
L-Formylkynurenine + H2O ⇄ Formate + L-Kynurenine (3.5.1.9)
H2O: h2o_c
L-Tryptophan + O2 ⇄ L-Formylkynurenine (1.13.11.11)
L-Tryptophan: trp__L_c, O2: o2_c
S-Adenosyl-L-methionine + Precorrin 2 ⇄ S-Adenosyl-L-homocysteine + Precorrin 3A + H+ (2.1.1.130)
S-Adenosyl-L-methionine: amet_c, Precorrin 2: dscl_c
S-Adenosyl-L-methionine + Precorrin 2 ⇄ S-Adenosyl-L-homocysteine + Precorrin 3A + H+ (2.1.1.130)
S-Adenosyl-L-methionine: amet_c, Precorrin 2: dscl_c
N2-Succinyl-L-ornithine + 2-Oxoglutarate ⇄ N-Succinyl-L-glutamate 5-semialdehyde + L-Glutamate (2.6.1.81)
2-Oxoglutarate: akg_c, N2-Succinyl-L-ornithine: sucorn_c
N2-Succinyl-L-ornithine + 2-Oxoglutarate ⇄ N-Succinyl-L-glutamate 5-semialdehyde + L-Glutamate (2.6.1.81)
2-Oxoglutarate: akg_c, N2-Succinyl-L-ornithine: sucorn_c
O-Phospho-4-hydroxy-L-threonine + 2-Oxoglutarate ⇄ 2-Oxo-3-hydroxy-4-phosphobutanoate + L-Glutamate (2.6.1.52)
2-Oxoglutarate: akg_c, O-Phospho-4-hydroxy-L-threonine: phthr_c
O-Phospho-4-hydroxy-L-threonine + 2-Oxoglutarate ⇄ 2-Oxo-3-hydroxy-4-phosphobutanoate + L-Glutamate (2.6.1.52)
2-Oxoglutarate: akg_c, O-Phospho-4-hydroxy-L-threonine: phthr_c
2-Oxo-3-hydroxy-4-phosphobutanoate + L-Glutamate ⇄ O-Phospho-4-hydroxy-L-threonine + 2-Oxoglutarate (2.6.1.52)
L-Glutamate: glu__L_c, 2-Oxo-3-hydroxy-4-phosphobutanoate: ohpb_c
2-Oxo-3-hydroxy-4-phosphobutanoate + L-Glutamate ⇄ O-Phospho-4-hydroxy-L-threonine + 2-Oxoglutarate (2.6.1.52)
L-Glutamate: glu__L_c, 2-Oxo-3-hydroxy-4-phosphobutanoate: ohpb_c
Precorrin 5 + S-Adenosyl-L-methionine + H2O ⇄ Precorrin 6X + Acetate + S-Adenosyl-L-homocysteine (2.1.1.152)
S-Adenosyl-L-methionine: amet_c, H2O: h2o_c
S-Adenosyl-L-methionine + Precorrin 4 ⇄ S-Adenosyl-L-homocysteine + Precorrin 5 (2.1.1.133)
S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + Precorrin 3B ⇄ S-Adenosyl-L-homocysteine + Precorrin 4 (2.1.1.131)
S-Adenosyl-L-methionine: amet_c
Precorrin 3A + O2 + NADH + H+ ⇄ Precorrin 3B + NAD+ + H2O (1.14.13.83)
O2: o2_c, NADH: nadh_c, H+: h_c
S-Adenosyl-L-methionine + Precorrin 2 ⇄ S-Adenosyl-L-homocysteine + Precorrin 3A + H+ (2.1.1.130)
S-Adenosyl-L-methionine: amet_c, Precorrin 2: dscl_c
Precorrin 5 + S-Adenosyl-L-methionine + H2O ⇄ Precorrin 6X + Acetate + S-Adenosyl-L-homocysteine (2.1.1.152)
S-Adenosyl-L-methionine: amet_c, H2O: h2o_c
S-Adenosyl-L-methionine + Precorrin 4 ⇄ S-Adenosyl-L-homocysteine + Precorrin 5 (2.1.1.133)
S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + Precorrin 3B ⇄ S-Adenosyl-L-homocysteine + Precorrin 4 (2.1.1.131)
S-Adenosyl-L-methionine: amet_c
Precorrin 3A + O2 + NADH + H+ ⇄ Precorrin 3B + NAD+ + H2O (1.14.13.83)
O2: o2_c, NADH: nadh_c, H+: h_c
S-Adenosyl-L-methionine + Precorrin 2 ⇄ S-Adenosyl-L-homocysteine + Precorrin 3A + H+ (2.1.1.130)
S-Adenosyl-L-methionine: amet_c, Precorrin 2: dscl_c
S-Adenosyl-L-methionine + myo-Inositol ⇄ S-Adenosyl-L-homocysteine + 4-O-Methyl-myo-inositol (2.1.1.129)
S-Adenosyl-L-methionine: amet_c, myo-Inositol: inost_c
S-Adenosyl-L-methionine + myo-Inositol ⇄ S-Adenosyl-L-homocysteine + 4-O-Methyl-myo-inositol (2.1.1.129)
S-Adenosyl-L-methionine: amet_c, myo-Inositol: inost_c
S-Adenosyl-L-methionine + Precorrin 3B ⇄ S-Adenosyl-L-homocysteine + Precorrin 4 (2.1.1.131)
S-Adenosyl-L-methionine: amet_c
Precorrin 3A + O2 + NADH + H+ ⇄ Precorrin 3B + NAD+ + H2O (1.14.13.83)
O2: o2_c, NADH: nadh_c, H+: h_c
S-Adenosyl-L-methionine + Precorrin 2 ⇄ S-Adenosyl-L-homocysteine + Precorrin 3A + H+ (2.1.1.130)
S-Adenosyl-L-methionine: amet_c, Precorrin 2: dscl_c
S-Adenosyl-L-methionine + Precorrin 3B ⇄ S-Adenosyl-L-homocysteine + Precorrin 4 (2.1.1.131)
S-Adenosyl-L-methionine: amet_c
Precorrin 3A + O2 + NADH + H+ ⇄ Precorrin 3B + NAD+ + H2O (1.14.13.83)
O2: o2_c, NADH: nadh_c, H+: h_c
S-Adenosyl-L-methionine + Precorrin 2 ⇄ S-Adenosyl-L-homocysteine + Precorrin 3A + H+ (2.1.1.130)
S-Adenosyl-L-methionine: amet_c, Precorrin 2: dscl_c
2 S-Adenosyl-L-methionine + Precorrin 6Y ⇄ 2 S-Adenosyl-L-homocysteine + Precorrin 8X + CO2 (2.1.1.132)
S-Adenosyl-L-methionine: amet_c
Precorrin 6X + NADPH + H+ ⇄ Precorrin 6Y + NADP+ (1.3.1.54)
NADPH: nadph_c, H+: h_c
Precorrin 5 + S-Adenosyl-L-methionine + H2O ⇄ Precorrin 6X + Acetate + S-Adenosyl-L-homocysteine (2.1.1.152)
S-Adenosyl-L-methionine: amet_c, H2O: h2o_c
S-Adenosyl-L-methionine + Precorrin 4 ⇄ S-Adenosyl-L-homocysteine + Precorrin 5 (2.1.1.133)
S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + Precorrin 3B ⇄ S-Adenosyl-L-homocysteine + Precorrin 4 (2.1.1.131)
S-Adenosyl-L-methionine: amet_c
Precorrin 3A + O2 + NADH + H+ ⇄ Precorrin 3B + NAD+ + H2O (1.14.13.83)
O2: o2_c, NADH: nadh_c, H+: h_c
S-Adenosyl-L-methionine + Precorrin 2 ⇄ S-Adenosyl-L-homocysteine + Precorrin 3A + H+ (2.1.1.130)
S-Adenosyl-L-methionine: amet_c, Precorrin 2: dscl_c
2 S-Adenosyl-L-methionine + Precorrin 6Y ⇄ 2 S-Adenosyl-L-homocysteine + Precorrin 8X + CO2 (2.1.1.132)
S-Adenosyl-L-methionine: amet_c
Precorrin 6X + NADPH + H+ ⇄ Precorrin 6Y + NADP+ (1.3.1.54)
NADPH: nadph_c, H+: h_c
Precorrin 5 + S-Adenosyl-L-methionine + H2O ⇄ Precorrin 6X + Acetate + S-Adenosyl-L-homocysteine (2.1.1.152)
S-Adenosyl-L-methionine: amet_c, H2O: h2o_c
S-Adenosyl-L-methionine + Precorrin 4 ⇄ S-Adenosyl-L-homocysteine + Precorrin 5 (2.1.1.133)
S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + Precorrin 3B ⇄ S-Adenosyl-L-homocysteine + Precorrin 4 (2.1.1.131)
S-Adenosyl-L-methionine: amet_c
Precorrin 3A + O2 + NADH + H+ ⇄ Precorrin 3B + NAD+ + H2O (1.14.13.83)
O2: o2_c, NADH: nadh_c, H+: h_c
S-Adenosyl-L-methionine + Precorrin 2 ⇄ S-Adenosyl-L-homocysteine + Precorrin 3A + H+ (2.1.1.130)
S-Adenosyl-L-methionine: amet_c, Precorrin 2: dscl_c
S-Adenosyl-L-methionine + Precorrin 4 ⇄ S-Adenosyl-L-homocysteine + Precorrin 5 (2.1.1.133)
S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + Precorrin 3B ⇄ S-Adenosyl-L-homocysteine + Precorrin 4 (2.1.1.131)
S-Adenosyl-L-methionine: amet_c
Precorrin 3A + O2 + NADH + H+ ⇄ Precorrin 3B + NAD+ + H2O (1.14.13.83)
O2: o2_c, NADH: nadh_c, H+: h_c
S-Adenosyl-L-methionine + Precorrin 2 ⇄ S-Adenosyl-L-homocysteine + Precorrin 3A + H+ (2.1.1.130)
S-Adenosyl-L-methionine: amet_c, Precorrin 2: dscl_c
S-Adenosyl-L-methionine + Precorrin 4 ⇄ S-Adenosyl-L-homocysteine + Precorrin 5 (2.1.1.133)
S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + Precorrin 3B ⇄ S-Adenosyl-L-homocysteine + Precorrin 4 (2.1.1.131)
S-Adenosyl-L-methionine: amet_c
Precorrin 3A + O2 + NADH + H+ ⇄ Precorrin 3B + NAD+ + H2O (1.14.13.83)
O2: o2_c, NADH: nadh_c, H+: h_c
S-Adenosyl-L-methionine + Precorrin 2 ⇄ S-Adenosyl-L-homocysteine + Precorrin 3A + H+ (2.1.1.130)
S-Adenosyl-L-methionine: amet_c, Precorrin 2: dscl_c
3,4-Dihydroxybenzoate + 5-Methyltetrahydrofolate ⇄ Vanillate + Tetrahydrofolate (2.1.1.341)
5-Methyltetrahydrofolate: 5mthf_c
3-Carboxy-cis,cis-muconate ⇄ 3,4-Dihydroxybenzoate + O2 (1.13.11.3)
2-Carboxy-2,5-dihydro-5-oxofuran-2-acetate ⇄ 3-Carboxy-cis,cis-muconate (5.5.1.2)
2-Oxo-2,3-dihydrofuran-5-acetate + CO2 ⇄ 2-Carboxy-2,5-dihydro-5-oxofuran-2-acetate (4.1.1.44)
CO2: co2_c
3-Oxoadipate ⇄ 2-Oxo-2,3-dihydrofuran-5-acetate + H2O (3.1.1.24)
Succinate + 3-Oxoadipyl-CoA ⇄ Succinyl-CoA + 3-Oxoadipate (2.8.3.6)
Succinate: succ_c, 3-Oxoadipyl-CoA: oxadpcoa_c
3,4-Dihydroxybenzoate + 5-Methyltetrahydrofolate ⇄ Vanillate + Tetrahydrofolate (2.1.1.341)
5-Methyltetrahydrofolate: 5mthf_c
3-Carboxy-cis,cis-muconate ⇄ 3,4-Dihydroxybenzoate + O2 (1.13.11.3)
2-Carboxy-2,5-dihydro-5-oxofuran-2-acetate ⇄ 3-Carboxy-cis,cis-muconate (5.5.1.2)
2-Oxo-2,3-dihydrofuran-5-acetate + CO2 ⇄ 2-Carboxy-2,5-dihydro-5-oxofuran-2-acetate (4.1.1.44)
CO2: co2_c
3-Oxoadipate ⇄ 2-Oxo-2,3-dihydrofuran-5-acetate + H2O (3.1.1.24)
Succinate + 3-Oxoadipyl-CoA ⇄ Succinyl-CoA + 3-Oxoadipate (2.8.3.6)
Succinate: succ_c, 3-Oxoadipyl-CoA: oxadpcoa_c
Arsenate ion + Thioredoxin ⇄ Arsenite + Thioredoxin disulfide + H2O (1.20.4.4)
Thioredoxin: trdrd_c, Arsenate ion: aso4_c
Arsenate ion + Thioredoxin ⇄ Arsenite + Thioredoxin disulfide + H2O (1.20.4.4)
Thioredoxin: trdrd_c, Arsenate ion: aso4_c
S-Adenosyl-L-methionine + 7-Methylxanthine ⇄ S-Adenosyl-L-homocysteine + Theobromine (2.1.1.159)
S-Adenosyl-L-methionine: amet_c
7-Methylxanthosine + H2O ⇄ 7-Methylxanthine + D-Ribose (3.2.2.25)
H2O: h2o_c
S-Adenosyl-L-methionine + Xanthosine ⇄ S-Adenosyl-L-homocysteine + 7-Methylxanthosine (2.1.1.158)
S-Adenosyl-L-methionine: amet_c, Xanthosine: xtsn_c
S-Adenosyl-L-methionine + 7-Methylxanthine ⇄ S-Adenosyl-L-homocysteine + Theobromine (2.1.1.160)
S-Adenosyl-L-methionine: amet_c
7-Methylxanthosine + H2O ⇄ 7-Methylxanthine + D-Ribose (3.2.2.25)
H2O: h2o_c
S-Adenosyl-L-methionine + Xanthosine ⇄ S-Adenosyl-L-homocysteine + 7-Methylxanthosine (2.1.1.158)
S-Adenosyl-L-methionine: amet_c, Xanthosine: xtsn_c
S-Adenosyl-L-methionine + 7-Methylxanthine ⇄ S-Adenosyl-L-homocysteine + Theobromine (2.1.1.159)
S-Adenosyl-L-methionine: amet_c
7-Methylxanthosine + H2O ⇄ 7-Methylxanthine + D-Ribose (3.2.2.25)
H2O: h2o_c
S-Adenosyl-L-methionine + Xanthosine ⇄ S-Adenosyl-L-homocysteine + 7-Methylxanthosine (2.1.1.158)
S-Adenosyl-L-methionine: amet_c, Xanthosine: xtsn_c
S-Adenosyl-L-methionine + 7-Methylxanthine ⇄ S-Adenosyl-L-homocysteine + Theobromine (2.1.1.160)
S-Adenosyl-L-methionine: amet_c
7-Methylxanthosine + H2O ⇄ 7-Methylxanthine + D-Ribose (3.2.2.25)
H2O: h2o_c
S-Adenosyl-L-methionine + Xanthosine ⇄ S-Adenosyl-L-homocysteine + 7-Methylxanthosine (2.1.1.158)
S-Adenosyl-L-methionine: amet_c, Xanthosine: xtsn_c
S-Adenosyl-L-methionine + Theobromine ⇄ S-Adenosyl-L-homocysteine + Caffeine (2.1.1.160)
S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + 7-Methylxanthine ⇄ S-Adenosyl-L-homocysteine + Theobromine (2.1.1.159)
S-Adenosyl-L-methionine: amet_c
7-Methylxanthosine + H2O ⇄ 7-Methylxanthine + D-Ribose (3.2.2.25)
H2O: h2o_c
S-Adenosyl-L-methionine + Xanthosine ⇄ S-Adenosyl-L-homocysteine + 7-Methylxanthosine (2.1.1.158)
S-Adenosyl-L-methionine: amet_c, Xanthosine: xtsn_c
S-Adenosyl-L-methionine + Theobromine ⇄ S-Adenosyl-L-homocysteine + Caffeine (2.1.1.160)
S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + 7-Methylxanthine ⇄ S-Adenosyl-L-homocysteine + Theobromine (2.1.1.159)
S-Adenosyl-L-methionine: amet_c
7-Methylxanthosine + H2O ⇄ 7-Methylxanthine + D-Ribose (3.2.2.25)
H2O: h2o_c
S-Adenosyl-L-methionine + Xanthosine ⇄ S-Adenosyl-L-homocysteine + 7-Methylxanthosine (2.1.1.158)
S-Adenosyl-L-methionine: amet_c, Xanthosine: xtsn_c
2 S-Adenosyl-L-methionine + Resveratrol ⇄ 2 S-Adenosyl-L-homocysteine + Pterostilbene (2.1.1.240)
S-Adenosyl-L-methionine: amet_c
3 Malonyl-CoA + p-Coumaroyl-CoA ⇄ 4 CoA + Resveratrol + 4 CO2 (2.3.1.95)
Malonyl-CoA: malcoa_c
ATP + 4-Coumarate + CoA ⇄ AMP + Diphosphate + p-Coumaroyl-CoA (6.2.1.12)
ATP: atp_c, CoA: coa_c
L-Tyrosine ⇄ 4-Coumarate + Ammonia (4.3.1.23)
L-Tyrosine: tyr__L_c
S-Adenosyl-L-methionine + 3-Methoxy-4',5-dihydroxy-trans-stilbene ⇄ S-Adenosyl-L-homocysteine + Pterostilbene (2.1.1.240)
S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + Resveratrol ⇄ S-Adenosyl-L-homocysteine + 3-Methoxy-4',5-dihydroxy-trans-stilbene (2.1.1.240)
S-Adenosyl-L-methionine: amet_c
3 Malonyl-CoA + p-Coumaroyl-CoA ⇄ 4 CoA + Resveratrol + 4 CO2 (2.3.1.95)
Malonyl-CoA: malcoa_c
ATP + 4-Coumarate + CoA ⇄ AMP + Diphosphate + p-Coumaroyl-CoA (6.2.1.12)
ATP: atp_c, CoA: coa_c
L-Tyrosine ⇄ 4-Coumarate + Ammonia (4.3.1.23)
L-Tyrosine: tyr__L_c
2 S-Adenosyl-L-methionine + Resveratrol ⇄ 2 S-Adenosyl-L-homocysteine + Pterostilbene (2.1.1.240)
S-Adenosyl-L-methionine: amet_c
3 Malonyl-CoA + p-Coumaroyl-CoA ⇄ 4 CoA + Resveratrol + 4 CO2 (2.3.1.95)
Malonyl-CoA: malcoa_c
ATP + 4-Coumarate + CoA ⇄ AMP + Diphosphate + p-Coumaroyl-CoA (6.2.1.12)
ATP: atp_c, CoA: coa_c
L-Tyrosine ⇄ 4-Coumarate + Ammonia (4.3.1.23)
L-Tyrosine: tyr__L_c
S-Adenosyl-L-methionine + 3-Methoxy-4',5-dihydroxy-trans-stilbene ⇄ S-Adenosyl-L-homocysteine + Pterostilbene (2.1.1.240)
S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + Resveratrol ⇄ S-Adenosyl-L-homocysteine + 3-Methoxy-4',5-dihydroxy-trans-stilbene (2.1.1.240)
S-Adenosyl-L-methionine: amet_c
3 Malonyl-CoA + p-Coumaroyl-CoA ⇄ 4 CoA + Resveratrol + 4 CO2 (2.3.1.95)
Malonyl-CoA: malcoa_c
ATP + 4-Coumarate + CoA ⇄ AMP + Diphosphate + p-Coumaroyl-CoA (6.2.1.12)
ATP: atp_c, CoA: coa_c
L-Tyrosine ⇄ 4-Coumarate + Ammonia (4.3.1.23)
L-Tyrosine: tyr__L_c
S-Adenosyl-L-methionine + Isoeugenol ⇄ S-Adenosyl-L-homocysteine + Methylisoeugenol (2.1.1.146)
S-Adenosyl-L-methionine: amet_c
4-Hydroxy-3-methoxy-benzaldehyde + Acetaldehyde ⇄ Isoeugenol + O2 (1.13.11.88)
Acetaldehyde: acald_c
Vanillate + NADH + H+ ⇄ 4-Hydroxy-3-methoxy-benzaldehyde + NAD+ + H2O (1.2.1.67)
NADH: nadh_c, H+: h_c
3,4-Dihydroxybenzoate + NAD+ + H2O + Formaldehyde ⇄ Vanillate + O2 + NADH + H+ (1.14.13.82)
NAD+: nad_c, H2O: h2o_c, Formaldehyde: fald_c
4-Hydroxybenzoate + O2 + NADPH + H+ ⇄ 3,4-Dihydroxybenzoate + NADP+ + H2O (1.14.13.2)
4-Hydroxybenzoate: 4hbz_c, O2: o2_c, NADPH: nadph_c, H+: h_c
S-Adenosyl-L-methionine + Isoeugenol ⇄ S-Adenosyl-L-homocysteine + Methylisoeugenol (2.1.1.279)
S-Adenosyl-L-methionine: amet_c
4-Hydroxy-3-methoxy-benzaldehyde + Acetaldehyde ⇄ Isoeugenol + O2 (1.13.11.88)
Acetaldehyde: acald_c
Vanillate + NADH + H+ ⇄ 4-Hydroxy-3-methoxy-benzaldehyde + NAD+ + H2O (1.2.1.67)
NADH: nadh_c, H+: h_c
3,4-Dihydroxybenzoate + NAD+ + H2O + Formaldehyde ⇄ Vanillate + O2 + NADH + H+ (1.14.13.82)
NAD+: nad_c, H2O: h2o_c, Formaldehyde: fald_c
4-Hydroxybenzoate + O2 + NADPH + H+ ⇄ 3,4-Dihydroxybenzoate + NADP+ + H2O (1.14.13.2)
4-Hydroxybenzoate: 4hbz_c, O2: o2_c, NADPH: nadph_c, H+: h_c
S-Adenosyl-L-methionine + Isoeugenol ⇄ S-Adenosyl-L-homocysteine + Methylisoeugenol (2.1.1.146)
S-Adenosyl-L-methionine: amet_c
4-Hydroxy-3-methoxy-benzaldehyde + Acetaldehyde ⇄ Isoeugenol + O2 (1.13.11.88)
Acetaldehyde: acald_c
Vanillate + NADH + H+ ⇄ 4-Hydroxy-3-methoxy-benzaldehyde + NAD+ + H2O (1.2.1.67)
NADH: nadh_c, H+: h_c
3,4-Dihydroxybenzoate + NAD+ + H2O + Formaldehyde ⇄ Vanillate + O2 + NADH + H+ (1.14.13.82)
NAD+: nad_c, H2O: h2o_c, Formaldehyde: fald_c
4-Hydroxybenzoate + O2 + NADPH + H+ ⇄ 3,4-Dihydroxybenzoate + NADP+ + H2O (1.14.13.2)
4-Hydroxybenzoate: 4hbz_c, O2: o2_c, NADPH: nadph_c, H+: h_c
S-Adenosyl-L-methionine + Isoeugenol ⇄ S-Adenosyl-L-homocysteine + Methylisoeugenol (2.1.1.279)
S-Adenosyl-L-methionine: amet_c
4-Hydroxy-3-methoxy-benzaldehyde + Acetaldehyde ⇄ Isoeugenol + O2 (1.13.11.88)
Acetaldehyde: acald_c
Vanillate + NADH + H+ ⇄ 4-Hydroxy-3-methoxy-benzaldehyde + NAD+ + H2O (1.2.1.67)
NADH: nadh_c, H+: h_c
3,4-Dihydroxybenzoate + NAD+ + H2O + Formaldehyde ⇄ Vanillate + O2 + NADH + H+ (1.14.13.82)
NAD+: nad_c, H2O: h2o_c, Formaldehyde: fald_c
4-Hydroxybenzoate + O2 + NADPH + H+ ⇄ 3,4-Dihydroxybenzoate + NADP+ + H2O (1.14.13.2)
4-Hydroxybenzoate: 4hbz_c, O2: o2_c, NADPH: nadph_c, H+: h_c
S-Adenosyl-L-methionine + trans-Aconitate ⇄ S-Adenosyl-L-homocysteine + (E)-3-(Methoxycarbonyl)pent-2-enedioate (2.1.1.144)
S-Adenosyl-L-methionine: amet_c, trans-Aconitate: acon_T_c
S-Adenosyl-L-methionine + trans-Aconitate ⇄ S-Adenosyl-L-homocysteine + (E)-3-(Methoxycarbonyl)pent-2-enedioate (2.1.1.144)
S-Adenosyl-L-methionine: amet_c, trans-Aconitate: acon_T_c
S-Adenosyl-L-methionine + trans-Aconitate ⇄ S-Adenosyl-L-homocysteine + (E)-2-(Methoxycarbonylmethyl)butenedioate (2.1.1.145)
S-Adenosyl-L-methionine: amet_c, trans-Aconitate: acon_T_c
S-Adenosyl-L-methionine + trans-Aconitate ⇄ S-Adenosyl-L-homocysteine + (E)-2-(Methoxycarbonylmethyl)butenedioate (2.1.1.145)
S-Adenosyl-L-methionine: amet_c, trans-Aconitate: acon_T_c
Magnesium protoporphyrin monomethyl ester + S-Adenosyl-L-methionine + H2O ⇄ 13(1)-Hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + 5'-Deoxyadenosine + L-Methionine (1.21.98.3)
S-Adenosyl-L-methionine: amet_c, H2O: h2o_c
S-Adenosyl-L-methionine + Magnesium protoporphyrin ⇄ S-Adenosyl-L-homocysteine + Magnesium protoporphyrin monomethyl ester (2.1.1.11)
S-Adenosyl-L-methionine: amet_c
ATP + Protoporphyrin + Magnesium cation + H2O ⇄ ADP + Orthophosphate + Magnesium protoporphyrin + 2 H+ (6.6.1.1)
ATP: atp_c, Protoporphyrin: ppp9_c, Magnesium cation: mg2_c, H2O: h2o_c
Magnesium protoporphyrin monomethyl ester + S-Adenosyl-L-methionine + H2O ⇄ 13(1)-Hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + 5'-Deoxyadenosine + L-Methionine (1.21.98.3)
S-Adenosyl-L-methionine: amet_c, H2O: h2o_c
S-Adenosyl-L-methionine + Magnesium protoporphyrin ⇄ S-Adenosyl-L-homocysteine + Magnesium protoporphyrin monomethyl ester (2.1.1.11)
S-Adenosyl-L-methionine: amet_c
ATP + Protoporphyrin + Magnesium cation + H2O ⇄ ADP + Orthophosphate + Magnesium protoporphyrin + 2 H+ (6.6.1.1)
ATP: atp_c, Protoporphyrin: ppp9_c, Magnesium cation: mg2_c, H2O: h2o_c
13(1)-Hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + S-Adenosyl-L-methionine ⇄ 13(1)-Oxo-magnesium-protoporphyrin IX 13-monomethyl ester + 5'-Deoxyadenosine + L-Methionine (1.21.98.3)
S-Adenosyl-L-methionine: amet_c
Magnesium protoporphyrin monomethyl ester + NADPH + H+ + O2 ⇄ 13(1)-Hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O (1.14.13.81)
NADPH: nadph_c, H+: h_c, O2: o2_c
S-Adenosyl-L-methionine + Magnesium protoporphyrin ⇄ S-Adenosyl-L-homocysteine + Magnesium protoporphyrin monomethyl ester (2.1.1.11)
S-Adenosyl-L-methionine: amet_c
ATP + Protoporphyrin + Magnesium cation + H2O ⇄ ADP + Orthophosphate + Magnesium protoporphyrin + 2 H+ (6.6.1.1)
ATP: atp_c, Protoporphyrin: ppp9_c, Magnesium cation: mg2_c, H2O: h2o_c
13(1)-Hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + S-Adenosyl-L-methionine ⇄ 13(1)-Oxo-magnesium-protoporphyrin IX 13-monomethyl ester + 5'-Deoxyadenosine + L-Methionine (1.21.98.3)
S-Adenosyl-L-methionine: amet_c
Magnesium protoporphyrin monomethyl ester + NADPH + H+ + O2 ⇄ 13(1)-Hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O (1.14.13.81)
NADPH: nadph_c, H+: h_c, O2: o2_c
S-Adenosyl-L-methionine + Magnesium protoporphyrin ⇄ S-Adenosyl-L-homocysteine + Magnesium protoporphyrin monomethyl ester (2.1.1.11)
S-Adenosyl-L-methionine: amet_c
ATP + Protoporphyrin + Magnesium cation + H2O ⇄ ADP + Orthophosphate + Magnesium protoporphyrin + 2 H+ (6.6.1.1)
ATP: atp_c, Protoporphyrin: ppp9_c, Magnesium cation: mg2_c, H2O: h2o_c
13(1)-Oxo-magnesium-protoporphyrin IX 13-monomethyl ester + S-Adenosyl-L-methionine ⇄ Divinylprotochlorophyllide + 5'-Deoxyadenosine + L-Methionine (1.21.98.3)
S-Adenosyl-L-methionine: amet_c
13(1)-Hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + O2 ⇄ 13(1)-Oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + 2 H2O (1.14.13.81)
NADPH: nadph_c, H+: h_c, O2: o2_c
Magnesium protoporphyrin monomethyl ester + NADPH + H+ + O2 ⇄ 13(1)-Hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O (1.14.13.81)
NADPH: nadph_c, H+: h_c, O2: o2_c
S-Adenosyl-L-methionine + Magnesium protoporphyrin ⇄ S-Adenosyl-L-homocysteine + Magnesium protoporphyrin monomethyl ester (2.1.1.11)
S-Adenosyl-L-methionine: amet_c
ATP + Protoporphyrin + Magnesium cation + H2O ⇄ ADP + Orthophosphate + Magnesium protoporphyrin + 2 H+ (6.6.1.1)
ATP: atp_c, Protoporphyrin: ppp9_c, Magnesium cation: mg2_c, H2O: h2o_c
13(1)-Oxo-magnesium-protoporphyrin IX 13-monomethyl ester + S-Adenosyl-L-methionine ⇄ Divinylprotochlorophyllide + 5'-Deoxyadenosine + L-Methionine (1.21.98.3)
S-Adenosyl-L-methionine: amet_c
13(1)-Hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + H+ + O2 ⇄ 13(1)-Oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + 2 H2O (1.14.13.81)
NADPH: nadph_c, H+: h_c, O2: o2_c
Magnesium protoporphyrin monomethyl ester + NADPH + H+ + O2 ⇄ 13(1)-Hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O (1.14.13.81)
NADPH: nadph_c, H+: h_c, O2: o2_c
S-Adenosyl-L-methionine + Magnesium protoporphyrin ⇄ S-Adenosyl-L-homocysteine + Magnesium protoporphyrin monomethyl ester (2.1.1.11)
S-Adenosyl-L-methionine: amet_c
ATP + Protoporphyrin + Magnesium cation + H2O ⇄ ADP + Orthophosphate + Magnesium protoporphyrin + 2 H+ (6.6.1.1)
ATP: atp_c, Protoporphyrin: ppp9_c, Magnesium cation: mg2_c, H2O: h2o_c
dTDP-4-amino-4,6-dideoxy-D-glucose + 2-Oxoglutarate ⇄ dTDP-4-oxo-6-deoxy-D-glucose + L-Glutamate (2.6.1.33)
2-Oxoglutarate: akg_c
dTDP-4-oxo-6-deoxy-D-glucose + L-Glutamate ⇄ dTDP-4-amino-4,6-dideoxy-D-glucose + 2-Oxoglutarate (2.6.1.33)
dTDP-4-oxo-6-deoxy-D-glucose: dtdp4d6dg_c, L-Glutamate: glu__L_c
dTDP-4-amino-4,6-dideoxy-D-galactose + 2-Oxoglutarate ⇄ dTDP-4-oxo-6-deoxy-D-glucose + L-Glutamate (2.6.1.59)
2-Oxoglutarate: akg_c, dTDP-4-amino-4,6-dideoxy-D-galactose: dtdp4addg_c
dTDP-4-amino-4,6-dideoxy-D-glucose + 2-Oxoglutarate ⇄ dTDP-4-oxo-6-deoxy-D-glucose + L-Glutamate (2.6.1.33)
2-Oxoglutarate: akg_c
dTDP-4-oxo-6-deoxy-D-glucose + L-Glutamate ⇄ dTDP-4-amino-4,6-dideoxy-D-glucose + 2-Oxoglutarate (2.6.1.33)
dTDP-4-oxo-6-deoxy-D-glucose: dtdp4d6dg_c, L-Glutamate: glu__L_c
dTDP-4-amino-4,6-dideoxy-D-galactose + 2-Oxoglutarate ⇄ dTDP-4-oxo-6-deoxy-D-glucose + L-Glutamate (2.6.1.59)
2-Oxoglutarate: akg_c, dTDP-4-amino-4,6-dideoxy-D-galactose: dtdp4addg_c
3,6-Dideoxy-3-oxo-dTDP-D-glucose + L-Glutamate ⇄ dTDP-3-amino-3,6-dideoxy-D-glucose + 2-Oxoglutarate (2.6.1.89)
L-Glutamate: glu__L_c
dTDP-4-oxo-6-deoxy-D-glucose ⇄ 3,6-Dideoxy-3-oxo-dTDP-D-glucose (5.3.2.4)
dTDP-4-oxo-6-deoxy-D-glucose: dtdp4d6dg_c
3,6-Dideoxy-3-oxo-dTDP-D-glucose + L-Glutamate ⇄ dTDP-3-amino-3,6-dideoxy-D-glucose + 2-Oxoglutarate (2.6.1.89)
L-Glutamate: glu__L_c
dTDP-4-oxo-6-deoxy-D-glucose ⇄ 3,6-Dideoxy-3-oxo-dTDP-D-glucose (5.3.2.4)
dTDP-4-oxo-6-deoxy-D-glucose: dtdp4d6dg_c
dTDP-3-amino-3,6-dideoxy-D-glucose + 2 S-Adenosyl-L-methionine ⇄ dTDP-D-mycaminose + 2 S-Adenosyl-L-homocysteine + 2 H+ (2.1.1.235)
S-Adenosyl-L-methionine: amet_c
3,6-Dideoxy-3-oxo-dTDP-D-glucose + L-Glutamate ⇄ dTDP-3-amino-3,6-dideoxy-D-glucose + 2-Oxoglutarate (2.6.1.89)
L-Glutamate: glu__L_c
dTDP-4-oxo-6-deoxy-D-glucose ⇄ 3,6-Dideoxy-3-oxo-dTDP-D-glucose (5.3.2.4)
dTDP-4-oxo-6-deoxy-D-glucose: dtdp4d6dg_c
dTDP-3-amino-3,6-dideoxy-D-glucose + 2 S-Adenosyl-L-methionine ⇄ dTDP-D-mycaminose + 2 S-Adenosyl-L-homocysteine + 2 H+ (2.1.1.235)
S-Adenosyl-L-methionine: amet_c
3,6-Dideoxy-3-oxo-dTDP-D-glucose + L-Glutamate ⇄ dTDP-3-amino-3,6-dideoxy-D-glucose + 2-Oxoglutarate (2.6.1.89)
L-Glutamate: glu__L_c
dTDP-4-oxo-6-deoxy-D-glucose ⇄ 3,6-Dideoxy-3-oxo-dTDP-D-glucose (5.3.2.4)
dTDP-4-oxo-6-deoxy-D-glucose: dtdp4d6dg_c
3,5-Dihydroxyphenylglyoxylate + L-Glutamate ⇄ 3,5-Dihydroxy-phenylglycine + 2-Oxoglutarate (2.6.1.103)
L-Glutamate: glu__L_c
3,5-Dihydroxyphenylacetyl-CoA + O2 ⇄ 3,5-Dihydroxyphenylglyoxylate + CoA (1.13.11.80)
O2: o2_c
4 Malonyl-CoA ⇄ 3,5-Dihydroxyphenylacetyl-CoA + 3 CoA + 4 CO2 + H2O (2.3.1.246)
Malonyl-CoA: malcoa_c
3,5-Dihydroxyphenylglyoxylate + L-Glutamate ⇄ 3,5-Dihydroxy-phenylglycine + 2-Oxoglutarate (2.6.1.103)
L-Glutamate: glu__L_c
3,5-Dihydroxyphenylacetyl-CoA + O2 ⇄ 3,5-Dihydroxyphenylglyoxylate + CoA (1.13.11.80)
O2: o2_c
4 Malonyl-CoA ⇄ 3,5-Dihydroxyphenylacetyl-CoA + 3 CoA + 4 CO2 + H2O (2.3.1.246)
Malonyl-CoA: malcoa_c
3-Dehydro-D-glucose 6-phosphate + L-Glutamate ⇄ Kanosamine 6-phosphate + 2-Oxoglutarate (2.6.1.104)
L-Glutamate: glu__L_c
D-Glucose 6-phosphate + NAD+ ⇄ 3-Dehydro-D-glucose 6-phosphate + NADH + H+ (1.1.1.361)
D-Glucose 6-phosphate: g6p_c, NAD+: nad_c
3-Dehydro-D-glucose 6-phosphate + L-Glutamate ⇄ Kanosamine 6-phosphate + 2-Oxoglutarate (2.6.1.104)
L-Glutamate: glu__L_c
D-Glucose 6-phosphate + NAD+ ⇄ 3-Dehydro-D-glucose 6-phosphate + NADH + H+ (1.1.1.361)
D-Glucose 6-phosphate: g6p_c, NAD+: nad_c
S-Adenosyl-L-methionine + Salicylate ⇄ S-Adenosyl-L-homocysteine + Methyl salicylate (2.1.1.274)
S-Adenosyl-L-methionine: amet_c
Catechol + CO2 + NAD+ + H2O ⇄ Salicylate + O2 + NADH + H+ (1.14.13.1)
CO2: co2_c, NAD+: nad_c, H2O: h2o_c
2-Hydroxymuconate semialdehyde ⇄ Catechol + O2 (1.13.11.2)
2-Hydroxy-2,4-pentadienoate + Formate ⇄ 2-Hydroxymuconate semialdehyde + H2O (3.7.1.9)
Formate: for_c
2-Hydroxy-6-ketononatrienedioate + H2O ⇄ 2-Hydroxy-2,4-pentadienoate + Fumarate (3.7.1.14)
2-Hydroxy-6-ketononatrienedioate: hkntd_c, H2O: h2o_c
2-Hydroxy-6-oxonona-2,4-diene-1,9-dioate + H2O ⇄ 2-Hydroxy-2,4-pentadienoate + Succinate (3.7.1.14)
2-Hydroxy-6-oxonona-2,4-diene-1,9-dioate: hkndd_c, H2O: h2o_c
S-Adenosyl-L-methionine + Salicylate ⇄ S-Adenosyl-L-homocysteine + Methyl salicylate (2.1.1.274)
S-Adenosyl-L-methionine: amet_c
Catechol + CO2 + NAD+ + H2O ⇄ Salicylate + O2 + NADH + H+ (1.14.13.1)
CO2: co2_c, NAD+: nad_c, H2O: h2o_c
2-Hydroxymuconate semialdehyde ⇄ Catechol + O2 (1.13.11.2)
2-Hydroxy-2,4-pentadienoate + Formate ⇄ 2-Hydroxymuconate semialdehyde + H2O (3.7.1.9)
Formate: for_c
2-Hydroxy-6-ketononatrienedioate + H2O ⇄ 2-Hydroxy-2,4-pentadienoate + Fumarate (3.7.1.14)
2-Hydroxy-6-ketononatrienedioate: hkntd_c, H2O: h2o_c
2-Hydroxy-6-oxonona-2,4-diene-1,9-dioate + H2O ⇄ 2-Hydroxy-2,4-pentadienoate + Succinate (3.7.1.14)
2-Hydroxy-6-oxonona-2,4-diene-1,9-dioate: hkndd_c, H2O: h2o_c
delta-Tocopherol + S-Adenosyl-L-methionine ⇄ beta-Tocopherol + S-Adenosyl-L-homocysteine (2.1.1.95)
S-Adenosyl-L-methionine: amet_c
2-Methyl-6-phytylquinol ⇄ delta-Tocopherol (5.5.1.24)
Phytyl diphosphate + Homogentisate ⇄ 2-Methyl-6-phytylquinol + Diphosphate + CO2 (2.5.1.115)
Geranylgeranyl diphosphate + 3 H+ + 3 NADPH ⇄ Phytyl diphosphate + 3 NADP+ (1.3.1.83)
H+: h_c, NADPH: nadph_c
trans,trans-Farnesyl diphosphate + Isopentenyl diphosphate ⇄ Diphosphate + Geranylgeranyl diphosphate (2.5.1.29)
trans,trans-Farnesyl diphosphate: frdp_c, Isopentenyl diphosphate: ipdp_c
4-Maleylacetoacetate ⇄ Homogentisate + O2 (1.13.11.5)
4-Fumarylacetoacetate ⇄ 4-Maleylacetoacetate (5.2.1.2)
Acetoacetate + Fumarate ⇄ 4-Fumarylacetoacetate + H2O (3.7.1.2)
Acetoacetate: acac_c, Fumarate: fum_c
delta-Tocopherol + S-Adenosyl-L-methionine ⇄ beta-Tocopherol + S-Adenosyl-L-homocysteine (2.1.1.95)
S-Adenosyl-L-methionine: amet_c
2-Methyl-6-phytylquinol ⇄ delta-Tocopherol (5.5.1.24)
Phytyl diphosphate + Homogentisate ⇄ 2-Methyl-6-phytylquinol + Diphosphate + CO2 (2.5.1.115)
Geranylgeranyl diphosphate + 3 H+ + 3 NADPH ⇄ Phytyl diphosphate + 3 NADP+ (1.3.1.83)
H+: h_c, NADPH: nadph_c
trans,trans-Farnesyl diphosphate + Isopentenyl diphosphate ⇄ Diphosphate + Geranylgeranyl diphosphate (2.5.1.29)
trans,trans-Farnesyl diphosphate: frdp_c, Isopentenyl diphosphate: ipdp_c
4-Maleylacetoacetate ⇄ Homogentisate + O2 (1.13.11.5)
4-Fumarylacetoacetate ⇄ 4-Maleylacetoacetate (5.2.1.2)
Acetoacetate + Fumarate ⇄ 4-Fumarylacetoacetate + H2O (3.7.1.2)
Acetoacetate: acac_c, Fumarate: fum_c
S-Adenosyl-L-methionine + gamma-Tocotrienol ⇄ S-Adenosyl-L-homocysteine + alpha-Tocotrienol (2.1.1.95)
S-Adenosyl-L-methionine: amet_c
6-Geranylgeranyl-2,3-dimethylbenzene-1,4-diol ⇄ gamma-Tocotrienol (5.5.1.24)
S-Adenosyl-L-methionine + 6-Geranylgeranyl-2-methylbenzene-1,4-diol ⇄ S-Adenosyl-L-homocysteine + 6-Geranylgeranyl-2,3-dimethylbenzene-1,4-diol (2.1.1.295)
S-Adenosyl-L-methionine: amet_c
Geranylgeranyl diphosphate + Homogentisate ⇄ Diphosphate + 6-Geranylgeranyl-2-methylbenzene-1,4-diol + CO2 (2.5.1.116)
trans,trans-Farnesyl diphosphate + Isopentenyl diphosphate ⇄ Diphosphate + Geranylgeranyl diphosphate (2.5.1.29)
trans,trans-Farnesyl diphosphate: frdp_c, Isopentenyl diphosphate: ipdp_c
4-Maleylacetoacetate ⇄ Homogentisate + O2 (1.13.11.5)
4-Fumarylacetoacetate ⇄ 4-Maleylacetoacetate (5.2.1.2)
Acetoacetate + Fumarate ⇄ 4-Fumarylacetoacetate + H2O (3.7.1.2)
Acetoacetate: acac_c, Fumarate: fum_c
S-Adenosyl-L-methionine + gamma-Tocotrienol ⇄ S-Adenosyl-L-homocysteine + alpha-Tocotrienol (2.1.1.95)
S-Adenosyl-L-methionine: amet_c
6-Geranylgeranyl-2,3-dimethylbenzene-1,4-diol ⇄ gamma-Tocotrienol (5.5.1.24)
S-Adenosyl-L-methionine + 6-Geranylgeranyl-2-methylbenzene-1,4-diol ⇄ S-Adenosyl-L-homocysteine + 6-Geranylgeranyl-2,3-dimethylbenzene-1,4-diol (2.1.1.295)
S-Adenosyl-L-methionine: amet_c
Geranylgeranyl diphosphate + Homogentisate ⇄ Diphosphate + 6-Geranylgeranyl-2-methylbenzene-1,4-diol + CO2 (2.5.1.116)
trans,trans-Farnesyl diphosphate + Isopentenyl diphosphate ⇄ Diphosphate + Geranylgeranyl diphosphate (2.5.1.29)
trans,trans-Farnesyl diphosphate: frdp_c, Isopentenyl diphosphate: ipdp_c
4-Maleylacetoacetate ⇄ Homogentisate + O2 (1.13.11.5)
4-Fumarylacetoacetate ⇄ 4-Maleylacetoacetate (5.2.1.2)
Acetoacetate + Fumarate ⇄ 4-Fumarylacetoacetate + H2O (3.7.1.2)
Acetoacetate: acac_c, Fumarate: fum_c
S-Adenosyl-L-methionine + delta-Tocotrienol ⇄ S-Adenosyl-L-homocysteine + beta-Tocotrienol (2.1.1.95)
S-Adenosyl-L-methionine: amet_c
6-Geranylgeranyl-2-methylbenzene-1,4-diol ⇄ delta-Tocotrienol (5.5.1.24)
Geranylgeranyl diphosphate + Homogentisate ⇄ Diphosphate + 6-Geranylgeranyl-2-methylbenzene-1,4-diol + CO2 (2.5.1.116)
trans,trans-Farnesyl diphosphate + Isopentenyl diphosphate ⇄ Diphosphate + Geranylgeranyl diphosphate (2.5.1.29)
trans,trans-Farnesyl diphosphate: frdp_c, Isopentenyl diphosphate: ipdp_c
4-Maleylacetoacetate ⇄ Homogentisate + O2 (1.13.11.5)
4-Fumarylacetoacetate ⇄ 4-Maleylacetoacetate (5.2.1.2)
Acetoacetate + Fumarate ⇄ 4-Fumarylacetoacetate + H2O (3.7.1.2)
Acetoacetate: acac_c, Fumarate: fum_c
S-Adenosyl-L-methionine + delta-Tocotrienol ⇄ S-Adenosyl-L-homocysteine + beta-Tocotrienol (2.1.1.95)
S-Adenosyl-L-methionine: amet_c
6-Geranylgeranyl-2-methylbenzene-1,4-diol ⇄ delta-Tocotrienol (5.5.1.24)
Geranylgeranyl diphosphate + Homogentisate ⇄ Diphosphate + 6-Geranylgeranyl-2-methylbenzene-1,4-diol + CO2 (2.5.1.116)
trans,trans-Farnesyl diphosphate + Isopentenyl diphosphate ⇄ Diphosphate + Geranylgeranyl diphosphate (2.5.1.29)
trans,trans-Farnesyl diphosphate: frdp_c, Isopentenyl diphosphate: ipdp_c
4-Maleylacetoacetate ⇄ Homogentisate + O2 (1.13.11.5)
4-Fumarylacetoacetate ⇄ 4-Maleylacetoacetate (5.2.1.2)
Acetoacetate + Fumarate ⇄ 4-Fumarylacetoacetate + H2O (3.7.1.2)
Acetoacetate: acac_c, Fumarate: fum_c
Nicotianamine + 2-Oxoglutarate ⇄ 3''-Deamino-3''-oxonicotianamine + L-Glutamate (2.6.1.80)
2-Oxoglutarate: akg_c
3 S-Adenosyl-L-methionine ⇄ 3 5'-Methylthioadenosine + Nicotianamine (2.5.1.43)
S-Adenosyl-L-methionine: amet_c
Nicotianamine + 2-Oxoglutarate ⇄ 3''-Deamino-3''-oxonicotianamine + L-Glutamate (2.6.1.80)
2-Oxoglutarate: akg_c
3 S-Adenosyl-L-methionine ⇄ 3 5'-Methylthioadenosine + Nicotianamine (2.5.1.43)
S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + Uroporphyrinogen III ⇄ S-Adenosyl-L-homocysteine + Precorrin 1 (2.1.1.107)
S-Adenosyl-L-methionine: amet_c, Uroporphyrinogen III: uppg3_c
S-Adenosyl-L-methionine + Uroporphyrinogen III ⇄ S-Adenosyl-L-homocysteine + Precorrin 1 (2.1.1.107)
S-Adenosyl-L-methionine: amet_c, Uroporphyrinogen III: uppg3_c
S-Adenosyl-L-methionine + Isoliquiritigenin ⇄ S-Adenosyl-L-homocysteine + 2'-O-Methylisoliquiritigenin (2.1.1.154)
S-Adenosyl-L-methionine: amet_c
p-Coumaroyl-CoA + 3 Malonyl-CoA + NADPH + H+ ⇄ Isoliquiritigenin + 4 CoA + 3 CO2 + NADP+ + H2O (2.3.1.170)
Malonyl-CoA: malcoa_c, NADPH: nadph_c, H+: h_c
ATP + 4-Coumarate + CoA ⇄ AMP + Diphosphate + p-Coumaroyl-CoA (6.2.1.12)
ATP: atp_c, CoA: coa_c
L-Tyrosine ⇄ 4-Coumarate + Ammonia (4.3.1.23)
L-Tyrosine: tyr__L_c
S-Adenosyl-L-methionine + Isoliquiritigenin ⇄ S-Adenosyl-L-homocysteine + 2'-O-Methylisoliquiritigenin (2.1.1.154)
S-Adenosyl-L-methionine: amet_c
p-Coumaroyl-CoA + 3 Malonyl-CoA + NADPH + H+ ⇄ Isoliquiritigenin + 4 CoA + 3 CO2 + NADP+ + H2O (2.3.1.170)
Malonyl-CoA: malcoa_c, NADPH: nadph_c, H+: h_c
ATP + 4-Coumarate + CoA ⇄ AMP + Diphosphate + p-Coumaroyl-CoA (6.2.1.12)
ATP: atp_c, CoA: coa_c
L-Tyrosine ⇄ 4-Coumarate + Ammonia (4.3.1.23)
L-Tyrosine: tyr__L_c
5-Amino-6-(1-D-ribitylamino)uracil + L-Tyrosine + S-Adenosyl-L-methionine ⇄ 5-Amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + Iminoglycine + L-Methionine + 5'-Deoxyadenosine (2.5.1.147)
S-Adenosyl-L-methionine: amet_c, 5-Amino-6-(1-D-ribitylamino)uracil: 4r5au_c, L-Tyrosine: tyr__L_c
5-Amino-6-(1-D-ribitylamino)uracil + L-Tyrosine + S-Adenosyl-L-methionine ⇄ 5-Amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + Iminoglycine + L-Methionine + 5'-Deoxyadenosine (2.5.1.147)
S-Adenosyl-L-methionine: amet_c, 5-Amino-6-(1-D-ribitylamino)uracil: 4r5au_c, L-Tyrosine: tyr__L_c
2-Methyl-6-phytylquinol + S-Adenosyl-L-methionine ⇄ 2,3-Dimethyl-5-phytylquinol + S-Adenosyl-L-homocysteine (2.1.1.295)
S-Adenosyl-L-methionine: amet_c
Phytyl diphosphate + Homogentisate ⇄ 2-Methyl-6-phytylquinol + Diphosphate + CO2 (2.5.1.115)
Geranylgeranyl diphosphate + 3 H+ + 3 NADPH ⇄ Phytyl diphosphate + 3 NADP+ (1.3.1.83)
H+: h_c, NADPH: nadph_c
trans,trans-Farnesyl diphosphate + Isopentenyl diphosphate ⇄ Diphosphate + Geranylgeranyl diphosphate (2.5.1.29)
trans,trans-Farnesyl diphosphate: frdp_c, Isopentenyl diphosphate: ipdp_c
4-Maleylacetoacetate ⇄ Homogentisate + O2 (1.13.11.5)
4-Fumarylacetoacetate ⇄ 4-Maleylacetoacetate (5.2.1.2)
Acetoacetate + Fumarate ⇄ 4-Fumarylacetoacetate + H2O (3.7.1.2)
Acetoacetate: acac_c, Fumarate: fum_c
2-Methyl-6-phytylquinol + S-Adenosyl-L-methionine ⇄ 2,3-Dimethyl-5-phytylquinol + S-Adenosyl-L-homocysteine (2.1.1.295)
S-Adenosyl-L-methionine: amet_c
Phytyl diphosphate + Homogentisate ⇄ 2-Methyl-6-phytylquinol + Diphosphate + CO2 (2.5.1.115)
Geranylgeranyl diphosphate + 3 H+ + 3 NADPH ⇄ Phytyl diphosphate + 3 NADP+ (1.3.1.83)
H+: h_c, NADPH: nadph_c
trans,trans-Farnesyl diphosphate + Isopentenyl diphosphate ⇄ Diphosphate + Geranylgeranyl diphosphate (2.5.1.29)
trans,trans-Farnesyl diphosphate: frdp_c, Isopentenyl diphosphate: ipdp_c
4-Maleylacetoacetate ⇄ Homogentisate + O2 (1.13.11.5)
4-Fumarylacetoacetate ⇄ 4-Maleylacetoacetate (5.2.1.2)
Acetoacetate + Fumarate ⇄ 4-Fumarylacetoacetate + H2O (3.7.1.2)
Acetoacetate: acac_c, Fumarate: fum_c
UDP-L-Ara4O + L-Glutamate ⇄ UDP-L-Ara4N + 2-Oxoglutarate (2.6.1.87)
L-Glutamate: glu__L_c, UDP-L-Ara4O: udpLa4o_c
UDP-L-Ara4O + L-Glutamate ⇄ UDP-L-Ara4N + 2-Oxoglutarate (2.6.1.87)
L-Glutamate: glu__L_c, UDP-L-Ara4O: udpLa4o_c
UDP-L-Ara4N + 2-Oxoglutarate ⇄ UDP-L-Ara4O + L-Glutamate (2.6.1.87)
2-Oxoglutarate: akg_c, UDP-L-Ara4N: udpLa4n_c
UDP-L-Ara4N + 2-Oxoglutarate ⇄ UDP-L-Ara4O + L-Glutamate (2.6.1.87)
2-Oxoglutarate: akg_c, UDP-L-Ara4N: udpLa4n_c
S-Adenosyl-L-methionine + Xanthosine ⇄ S-Adenosyl-L-homocysteine + 7-Methylxanthosine (2.1.1.158)
S-Adenosyl-L-methionine: amet_c, Xanthosine: xtsn_c
S-Adenosyl-L-methionine + Xanthosine ⇄ S-Adenosyl-L-homocysteine + 7-Methylxanthosine (2.1.1.158)
S-Adenosyl-L-methionine: amet_c, Xanthosine: xtsn_c
4-Hydroxy-3-methoxy-benzaldehyde + L-Alanine ⇄ Vanillylamine + Pyruvate (2.6.1.119)
L-Alanine: ala__L_c
Vanillate + NADH + H+ ⇄ 4-Hydroxy-3-methoxy-benzaldehyde + NAD+ + H2O (1.2.1.67)
NADH: nadh_c, H+: h_c
3,4-Dihydroxybenzoate + NAD+ + H2O + Formaldehyde ⇄ Vanillate + O2 + NADH + H+ (1.14.13.82)
NAD+: nad_c, H2O: h2o_c, Formaldehyde: fald_c
3-Carboxy-cis,cis-muconate ⇄ 3,4-Dihydroxybenzoate + O2 (1.13.11.3)
2-Carboxy-2,5-dihydro-5-oxofuran-2-acetate ⇄ 3-Carboxy-cis,cis-muconate (5.5.1.2)
2-Oxo-2,3-dihydrofuran-5-acetate + CO2 ⇄ 2-Carboxy-2,5-dihydro-5-oxofuran-2-acetate (4.1.1.44)
CO2: co2_c
3-Oxoadipate ⇄ 2-Oxo-2,3-dihydrofuran-5-acetate + H2O (3.1.1.24)
Succinate + 3-Oxoadipyl-CoA ⇄ Succinyl-CoA + 3-Oxoadipate (2.8.3.6)
Succinate: succ_c, 3-Oxoadipyl-CoA: oxadpcoa_c
4-Hydroxy-3-methoxy-benzaldehyde + L-Alanine ⇄ Vanillylamine + Pyruvate (2.6.1.119)
L-Alanine: ala__L_c
Vanillate + NADH + H+ ⇄ 4-Hydroxy-3-methoxy-benzaldehyde + NAD+ + H2O (1.2.1.67)
NADH: nadh_c, H+: h_c
3,4-Dihydroxybenzoate + NAD+ + H2O + Formaldehyde ⇄ Vanillate + O2 + NADH + H+ (1.14.13.82)
NAD+: nad_c, H2O: h2o_c, Formaldehyde: fald_c
3-Carboxy-cis,cis-muconate ⇄ 3,4-Dihydroxybenzoate + O2 (1.13.11.3)
2-Carboxy-2,5-dihydro-5-oxofuran-2-acetate ⇄ 3-Carboxy-cis,cis-muconate (5.5.1.2)
2-Oxo-2,3-dihydrofuran-5-acetate + CO2 ⇄ 2-Carboxy-2,5-dihydro-5-oxofuran-2-acetate (4.1.1.44)
CO2: co2_c
3-Oxoadipate ⇄ 2-Oxo-2,3-dihydrofuran-5-acetate + H2O (3.1.1.24)
Succinate + 3-Oxoadipyl-CoA ⇄ Succinyl-CoA + 3-Oxoadipate (2.8.3.6)
Succinate: succ_c, 3-Oxoadipyl-CoA: oxadpcoa_c
S-Adenosyl-L-methionine + 2-Methyl-6-solanyl-1,4-benzoquinol ⇄ S-Adenosyl-L-homocysteine + Plastoquinol-9 (2.1.1.295)
S-Adenosyl-L-methionine: amet_c
Homogentisate + all-trans-Nonaprenyl diphosphate ⇄ 2-Methyl-6-solanyl-1,4-benzoquinol + Diphosphate + CO2 (2.5.1.117)
4-Maleylacetoacetate ⇄ Homogentisate + O2 (1.13.11.5)
4-Fumarylacetoacetate ⇄ 4-Maleylacetoacetate (5.2.1.2)
Acetoacetate + Fumarate ⇄ 4-Fumarylacetoacetate + H2O (3.7.1.2)
Acetoacetate: acac_c, Fumarate: fum_c
Geranyl diphosphate + 7 Isopentenyl diphosphate ⇄ all-trans-Nonaprenyl diphosphate + 7 Diphosphate (2.5.1.84)
Geranyl diphosphate: grdp_c, Isopentenyl diphosphate: ipdp_c
S-Adenosyl-L-methionine + 2-Methyl-6-solanyl-1,4-benzoquinol ⇄ S-Adenosyl-L-homocysteine + Plastoquinol-9 (2.1.1.295)
S-Adenosyl-L-methionine: amet_c
Homogentisate + all-trans-Nonaprenyl diphosphate ⇄ 2-Methyl-6-solanyl-1,4-benzoquinol + Diphosphate + CO2 (2.5.1.117)
4-Maleylacetoacetate ⇄ Homogentisate + O2 (1.13.11.5)
4-Fumarylacetoacetate ⇄ 4-Maleylacetoacetate (5.2.1.2)
Acetoacetate + Fumarate ⇄ 4-Fumarylacetoacetate + H2O (3.7.1.2)
Acetoacetate: acac_c, Fumarate: fum_c
Geranyl diphosphate + 7 Isopentenyl diphosphate ⇄ all-trans-Nonaprenyl diphosphate + 7 Diphosphate (2.5.1.84)
Geranyl diphosphate: grdp_c, Isopentenyl diphosphate: ipdp_c
S-Adenosyl-L-methionine + L-Tryptophan ⇄ S-Adenosyl-L-homocysteine + L-2-Methyltryptophan (2.1.1.106)
S-Adenosyl-L-methionine: amet_c, L-Tryptophan: trp__L_c
S-Adenosyl-L-methionine + L-Tryptophan ⇄ S-Adenosyl-L-homocysteine + L-2-Methyltryptophan (2.1.1.106)
S-Adenosyl-L-methionine: amet_c, L-Tryptophan: trp__L_c
Cobalt-sirohydrochlorin + S-Adenosyl-L-methionine ⇄ Cobalt-factor III + S-Adenosyl-L-homocysteine (2.1.1.151)
S-Adenosyl-L-methionine: amet_c
Sirohydrochlorin + Cobalt ion ⇄ Cobalt-sirohydrochlorin + 2 H+ (4.99.1.3)
Sirohydrochlorin: scl_c, Cobalt ion: cobalt2_c
Cobalt-sirohydrochlorin + S-Adenosyl-L-methionine ⇄ Cobalt-factor III + S-Adenosyl-L-homocysteine (2.1.1.151)
S-Adenosyl-L-methionine: amet_c
Sirohydrochlorin + Cobalt ion ⇄ Cobalt-sirohydrochlorin + 2 H+ (4.99.1.3)
Sirohydrochlorin: scl_c, Cobalt ion: cobalt2_c
2-Deoxy-scyllo-inosamine + S-Adenosyl-L-methionine ⇄ 3-Amino-2,3-dideoxy-scyllo-inosose + L-Methionine + 5'-Deoxyadenosine (1.1.99.38)
S-Adenosyl-L-methionine: amet_c
2-Deoxy-scyllo-inosose + L-Glutamine ⇄ 2-Deoxy-scyllo-inosamine + 2-Oxoglutaramate (2.6.1.100)
L-Glutamine: gln__L_c
D-Glucose 6-phosphate ⇄ 2-Deoxy-scyllo-inosose + Orthophosphate (4.2.3.124)
D-Glucose 6-phosphate: g6p_c
2-Deoxy-scyllo-inosamine + S-Adenosyl-L-methionine ⇄ 3-Amino-2,3-dideoxy-scyllo-inosose + L-Methionine + 5'-Deoxyadenosine (1.1.99.38)
S-Adenosyl-L-methionine: amet_c
2-Deoxy-scyllo-inosose + L-Glutamine ⇄ 2-Deoxy-scyllo-inosamine + 2-Oxoglutaramate (2.6.1.100)
L-Glutamine: gln__L_c
D-Glucose 6-phosphate ⇄ 2-Deoxy-scyllo-inosose + Orthophosphate (4.2.3.124)
D-Glucose 6-phosphate: g6p_c
5-Amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + S-Adenosyl-L-methionine ⇄ 7,8-Didemethyl-8-hydroxy-5-deazariboflavin + Ammonia + L-Methionine + 5'-Deoxyadenosine (4.3.1.32)
S-Adenosyl-L-methionine: amet_c
5-Amino-6-(1-D-ribitylamino)uracil + L-Tyrosine + S-Adenosyl-L-methionine ⇄ 5-Amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + Iminoglycine + L-Methionine + 5'-Deoxyadenosine (2.5.1.147)
5-Amino-6-(1-D-ribitylamino)uracil: 4r5au_c, L-Tyrosine: tyr__L_c, S-Adenosyl-L-methionine: amet_c
5-Amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + S-Adenosyl-L-methionine ⇄ 7,8-Didemethyl-8-hydroxy-5-deazariboflavin + Ammonia + L-Methionine + 5'-Deoxyadenosine (4.3.1.32)
S-Adenosyl-L-methionine: amet_c
5-Amino-6-(1-D-ribitylamino)uracil + L-Tyrosine + S-Adenosyl-L-methionine ⇄ 5-Amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + Iminoglycine + L-Methionine + 5'-Deoxyadenosine (2.5.1.147)
5-Amino-6-(1-D-ribitylamino)uracil: 4r5au_c, L-Tyrosine: tyr__L_c, S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + Malonyl-[acyl-carrier protein] ⇄ S-Adenosyl-L-homocysteine + Malonyl-[acp] methyl ester (2.1.1.197)
S-Adenosyl-L-methionine: amet_c, Malonyl-[acyl-carrier protein]: malACP_c
S-Adenosyl-L-methionine + Malonyl-[acyl-carrier protein] ⇄ S-Adenosyl-L-homocysteine + Malonyl-[acp] methyl ester (2.1.1.197)
S-Adenosyl-L-methionine: amet_c, Malonyl-[acyl-carrier protein]: malACP_c
4'-O-Demethylrebeccamycin + S-Adenosyl-L-methionine ⇄ Rebeccamycin + S-Adenosyl-L-homocysteine (2.1.1.164)
S-Adenosyl-L-methionine: amet_c
Dichloroarcyriaflavin A + beta-D-Glucose ⇄ 4'-O-Demethylrebeccamycin + H2O (4.3.3.5)
3,4-Bis(7-chloroindol-3-yl)pyrrole-2,5-dicarboxylate + 4 O2 + 4 NADH + 4 H+ ⇄ Dichloroarcyriaflavin A + 2 CO2 + 6 H2O + 4 NAD+ (1.13.12.17)
O2: o2_c, NADH: nadh_c, H+: h_c
4 2-Imino-3-(7-chloroindol-3-yl)propanoate + O2 ⇄ 2 3,4-Bis(7-chloroindol-3-yl)pyrrole-2,5-dicarboxylate + 2 Ammonia + 2 H2O (1.21.98.2)
O2: o2_c
7-Chloro-L-tryptophan + O2 ⇄ 2-Imino-3-(7-chloroindol-3-yl)propanoate + Hydrogen peroxide (1.4.3.23)
O2: o2_c
L-Tryptophan + FADH2 + Cl- + O2 + H+ ⇄ 7-Chloro-L-tryptophan + FAD + 2 H2O (1.14.19.9)
L-Tryptophan: trp__L_c, FADH2: fadh2_c, Cl-: cl_c, O2: o2_c, H+: h_c
D-Glucono-1,5-lactone + Hydrogen peroxide ⇄ beta-D-Glucose + O2 (1.1.3.4)
Hydrogen peroxide: h2o2_c
D-Glucose + NAD+ ⇄ D-Glucono-1,5-lactone + NADH + H+ (1.1.1.118)
D-Glucose: glc__D_c, NAD+: nad_c
4'-O-Demethylrebeccamycin + S-Adenosyl-L-methionine ⇄ Rebeccamycin + S-Adenosyl-L-homocysteine (2.1.1.164)
S-Adenosyl-L-methionine: amet_c
Dichloroarcyriaflavin A + beta-D-Glucose ⇄ 4'-O-Demethylrebeccamycin + H2O (4.3.3.5)
3,4-Bis(7-chloroindol-3-yl)pyrrole-2,5-dicarboxylate + 4 O2 + 4 NADH + 4 H+ ⇄ Dichloroarcyriaflavin A + 2 CO2 + 6 H2O + 4 NAD+ (1.13.12.17)
O2: o2_c, NADH: nadh_c, H+: h_c
4 2-Imino-3-(7-chloroindol-3-yl)propanoate + O2 ⇄ 2 3,4-Bis(7-chloroindol-3-yl)pyrrole-2,5-dicarboxylate + 2 Ammonia + 2 H2O (1.21.98.2)
O2: o2_c
7-Chloro-L-tryptophan + O2 ⇄ 2-Imino-3-(7-chloroindol-3-yl)propanoate + Hydrogen peroxide (1.4.3.23)
O2: o2_c
L-Tryptophan + FADH2 + Cl- + O2 + H+ ⇄ 7-Chloro-L-tryptophan + FAD + 2 H2O (1.14.19.9)
L-Tryptophan: trp__L_c, FADH2: fadh2_c, Cl-: cl_c, O2: o2_c, H+: h_c
D-Glucono-1,5-lactone + Hydrogen peroxide ⇄ beta-D-Glucose + O2 (1.1.3.4)
Hydrogen peroxide: h2o2_c
D-Glucose + NAD+ ⇄ D-Glucono-1,5-lactone + NADH + H+ (1.1.1.118)
D-Glucose: glc__D_c, NAD+: nad_c
dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose + L-Glutamate ⇄ dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose + 2-Oxoglutarate (2.6.1.90)
L-Glutamate: glu__L_c
dTDP-4-oxo-6-deoxy-D-glucose ⇄ dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose (5.3.2.3)
dTDP-4-oxo-6-deoxy-D-glucose: dtdp4d6dg_c
dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose + L-Glutamate ⇄ dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose + 2-Oxoglutarate (2.6.1.90)
L-Glutamate: glu__L_c
dTDP-4-oxo-6-deoxy-D-glucose ⇄ dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose (5.3.2.3)
dTDP-4-oxo-6-deoxy-D-glucose: dtdp4d6dg_c
dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose + 2 S-Adenosyl-L-methionine ⇄ dTDP-3-dimethylamino-3,6-dideoxy-alpha-D-galactopyranose + 2 S-Adenosyl-L-homocysteine (2.1.1.236)
S-Adenosyl-L-methionine: amet_c
dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose + L-Glutamate ⇄ dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose + 2-Oxoglutarate (2.6.1.90)
L-Glutamate: glu__L_c
dTDP-4-oxo-6-deoxy-D-glucose ⇄ dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose (5.3.2.3)
dTDP-4-oxo-6-deoxy-D-glucose: dtdp4d6dg_c
dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose + 2 S-Adenosyl-L-methionine ⇄ dTDP-3-dimethylamino-3,6-dideoxy-alpha-D-galactopyranose + 2 S-Adenosyl-L-homocysteine (2.1.1.236)
S-Adenosyl-L-methionine: amet_c
dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose + L-Glutamate ⇄ dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose + 2-Oxoglutarate (2.6.1.90)
L-Glutamate: glu__L_c
dTDP-4-oxo-6-deoxy-D-glucose ⇄ dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose (5.3.2.3)
dTDP-4-oxo-6-deoxy-D-glucose: dtdp4d6dg_c
UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hexos-4-ulose + L-Glutamate ⇄ UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine + 2-Oxoglutarate (2.6.1.92)
L-Glutamate: glu__L_c
UDP-N-acetyl-alpha-D-glucosamine ⇄ UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hexos-4-ulose + H2O (4.2.1.115)
UDP-N-acetyl-alpha-D-glucosamine: uacgam_c
UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hexos-4-ulose + L-Glutamate ⇄ UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine + 2-Oxoglutarate (2.6.1.92)
L-Glutamate: glu__L_c
UDP-N-acetyl-alpha-D-glucosamine ⇄ UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hexos-4-ulose + H2O (4.2.1.115)
UDP-N-acetyl-alpha-D-glucosamine: uacgam_c
S-Adenosyl-L-methionine + Resveratrol ⇄ S-Adenosyl-L-homocysteine + 3-Methoxy-4',5-dihydroxy-trans-stilbene (2.1.1.240)
S-Adenosyl-L-methionine: amet_c
3 Malonyl-CoA + p-Coumaroyl-CoA ⇄ 4 CoA + Resveratrol + 4 CO2 (2.3.1.95)
Malonyl-CoA: malcoa_c
ATP + 4-Coumarate + CoA ⇄ AMP + Diphosphate + p-Coumaroyl-CoA (6.2.1.12)
ATP: atp_c, CoA: coa_c
L-Tyrosine ⇄ 4-Coumarate + Ammonia (4.3.1.23)
L-Tyrosine: tyr__L_c
S-Adenosyl-L-methionine + Resveratrol ⇄ S-Adenosyl-L-homocysteine + 3-Methoxy-4',5-dihydroxy-trans-stilbene (2.1.1.240)
S-Adenosyl-L-methionine: amet_c
3 Malonyl-CoA + p-Coumaroyl-CoA ⇄ 4 CoA + Resveratrol + 4 CO2 (2.3.1.95)
Malonyl-CoA: malcoa_c
ATP + 4-Coumarate + CoA ⇄ AMP + Diphosphate + p-Coumaroyl-CoA (6.2.1.12)
ATP: atp_c, CoA: coa_c
L-Tyrosine ⇄ 4-Coumarate + Ammonia (4.3.1.23)
L-Tyrosine: tyr__L_c
S-Adenosyl-L-methionine + 5-Guanidino-2-oxopentanoate ⇄ S-Adenosyl-L-homocysteine + 5-Guanidino-3-methyl-2-oxopentanoate (2.1.1.243)
S-Adenosyl-L-methionine: amet_c
L-Arginine + H2O + O2 ⇄ 5-Guanidino-2-oxopentanoate + Ammonia + Hydrogen peroxide (1.4.3.25)
L-Arginine: arg__L_c, H2O: h2o_c, O2: o2_c
S-Adenosyl-L-methionine + 5-Guanidino-2-oxopentanoate ⇄ S-Adenosyl-L-homocysteine + 5-Guanidino-3-methyl-2-oxopentanoate (2.1.1.243)
S-Adenosyl-L-methionine: amet_c
L-Arginine + H2O + O2 ⇄ 5-Guanidino-2-oxopentanoate + Ammonia + Hydrogen peroxide (1.4.3.25)
L-Arginine: arg__L_c, H2O: h2o_c, O2: o2_c
S-Adenosyl-L-methionine + Geranyl diphosphate ⇄ S-Adenosyl-L-homocysteine + (E)-2-Methylgeranyl diphosphate (2.1.1.255)
S-Adenosyl-L-methionine: amet_c, Geranyl diphosphate: grdp_c
S-Adenosyl-L-methionine + Geranyl diphosphate ⇄ S-Adenosyl-L-homocysteine + (E)-2-Methylgeranyl diphosphate (2.1.1.255)
S-Adenosyl-L-methionine: amet_c, Geranyl diphosphate: grdp_c
UDP-2-acetamido-2-deoxy-alpha-D-ribo-hex-3-uluronate + L-Glutamate ⇄ UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucuronate + 2-Oxoglutarate (2.6.1.98)
L-Glutamate: glu__L_c
UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate + NAD+ ⇄ UDP-2-acetamido-2-deoxy-alpha-D-ribo-hex-3-uluronate + NADH + H+ (1.1.1.335)
NAD+: nad_c
UDP-N-acetyl-alpha-D-glucosamine + 2 NAD+ + H2O ⇄ UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate + 2 NADH + 2 H+ (1.1.1.136)
UDP-N-acetyl-alpha-D-glucosamine: uacgam_c, NAD+: nad_c, H2O: h2o_c
UDP-2-acetamido-2-deoxy-alpha-D-ribo-hex-3-uluronate + L-Glutamate ⇄ UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucuronate + 2-Oxoglutarate (2.6.1.98)
L-Glutamate: glu__L_c
UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate + NAD+ ⇄ UDP-2-acetamido-2-deoxy-alpha-D-ribo-hex-3-uluronate + NADH + H+ (1.1.1.335)
NAD+: nad_c
UDP-N-acetyl-alpha-D-glucosamine + 2 NAD+ + H2O ⇄ UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate + 2 NADH + 2 H+ (1.1.1.136)
UDP-N-acetyl-alpha-D-glucosamine: uacgam_c, NAD+: nad_c, H2O: h2o_c
4-(3-Methylbut-2-enyl)-L-tryptophan + S-Adenosyl-L-methionine ⇄ 4-Dimethylallyl-L-abrine + S-Adenosyl-L-homocysteine (2.1.1.261)
S-Adenosyl-L-methionine: amet_c
Dimethylallyl diphosphate + L-Tryptophan ⇄ Diphosphate + 4-(3-Methylbut-2-enyl)-L-tryptophan (2.5.1.34)
Dimethylallyl diphosphate: dmpp_c, L-Tryptophan: trp__L_c
4-(3-Methylbut-2-enyl)-L-tryptophan + S-Adenosyl-L-methionine ⇄ 4-Dimethylallyl-L-abrine + S-Adenosyl-L-homocysteine (2.1.1.261)
S-Adenosyl-L-methionine: amet_c
Dimethylallyl diphosphate + L-Tryptophan ⇄ Diphosphate + 4-(3-Methylbut-2-enyl)-L-tryptophan (2.5.1.34)
Dimethylallyl diphosphate: dmpp_c, L-Tryptophan: trp__L_c
S-Adenosyl-L-methionine + Squalene ⇄ S-Adenosyl-L-homocysteine + 3-Methyl-1,2-didehydro-2,3-dihydrosqualene (2.1.1.262)
S-Adenosyl-L-methionine: amet_c
Presqualene diphosphate + NADPH + H+ ⇄ Diphosphate + Squalene + NADP+ (1.3.1.96)
NADPH: nadph_c, H+: h_c
2 trans,trans-Farnesyl diphosphate ⇄ Diphosphate + Presqualene diphosphate (2.5.1.21)
trans,trans-Farnesyl diphosphate: frdp_c
S-Adenosyl-L-methionine + Squalene ⇄ S-Adenosyl-L-homocysteine + 3-Methyl-1,2-didehydro-2,3-dihydrosqualene (2.1.1.262)
S-Adenosyl-L-methionine: amet_c
Presqualene diphosphate + NADPH + H+ ⇄ Diphosphate + Squalene + NADP+ (1.3.1.96)
NADPH: nadph_c, H+: h_c
2 trans,trans-Farnesyl diphosphate ⇄ Diphosphate + Presqualene diphosphate (2.5.1.21)
trans,trans-Farnesyl diphosphate: frdp_c
2 S-Adenosyl-L-methionine + Squalene ⇄ 2 S-Adenosyl-L-homocysteine + 3,22-Dimethyl-1,2,23,24-tetradehydro-2,3,22,23-tetrahydrosqualene (2.1.1.262)
S-Adenosyl-L-methionine: amet_c
Presqualene diphosphate + NADPH + H+ ⇄ Diphosphate + Squalene + NADP+ (1.3.1.96)
NADPH: nadph_c, H+: h_c
2 trans,trans-Farnesyl diphosphate ⇄ Diphosphate + Presqualene diphosphate (2.5.1.21)
trans,trans-Farnesyl diphosphate: frdp_c
S-Adenosyl-L-methionine + 3-Methyl-1,2-didehydro-2,3-dihydrosqualene ⇄ S-Adenosyl-L-homocysteine + 3,22-Dimethyl-1,2,23,24-tetradehydro-2,3,22,23-tetrahydrosqualene (2.1.1.262)
S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + Squalene ⇄ S-Adenosyl-L-homocysteine + 3-Methyl-1,2-didehydro-2,3-dihydrosqualene (2.1.1.262)
S-Adenosyl-L-methionine: amet_c
Presqualene diphosphate + NADPH + H+ ⇄ Diphosphate + Squalene + NADP+ (1.3.1.96)
NADPH: nadph_c, H+: h_c
2 trans,trans-Farnesyl diphosphate ⇄ Diphosphate + Presqualene diphosphate (2.5.1.21)
trans,trans-Farnesyl diphosphate: frdp_c
2 S-Adenosyl-L-methionine + Squalene ⇄ 2 S-Adenosyl-L-homocysteine + 3,22-Dimethyl-1,2,23,24-tetradehydro-2,3,22,23-tetrahydrosqualene (2.1.1.262)
S-Adenosyl-L-methionine: amet_c
Presqualene diphosphate + NADPH + H+ ⇄ Diphosphate + Squalene + NADP+ (1.3.1.96)
NADPH: nadph_c, H+: h_c
2 trans,trans-Farnesyl diphosphate ⇄ Diphosphate + Presqualene diphosphate (2.5.1.21)
trans,trans-Farnesyl diphosphate: frdp_c
S-Adenosyl-L-methionine + 3-Methyl-1,2-didehydro-2,3-dihydrosqualene ⇄ S-Adenosyl-L-homocysteine + 3,22-Dimethyl-1,2,23,24-tetradehydro-2,3,22,23-tetrahydrosqualene (2.1.1.262)
S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + Squalene ⇄ S-Adenosyl-L-homocysteine + 3-Methyl-1,2-didehydro-2,3-dihydrosqualene (2.1.1.262)
S-Adenosyl-L-methionine: amet_c
Presqualene diphosphate + NADPH + H+ ⇄ Diphosphate + Squalene + NADP+ (1.3.1.96)
NADPH: nadph_c, H+: h_c
2 trans,trans-Farnesyl diphosphate ⇄ Diphosphate + Presqualene diphosphate (2.5.1.21)
trans,trans-Farnesyl diphosphate: frdp_c
S-Adenosyl-L-methionine + C30 Botryococcene ⇄ S-Adenosyl-L-homocysteine + 3-Methyl-1,2-didehydro-2,3-dihydrobotryococcene (2.1.1.263)
S-Adenosyl-L-methionine: amet_c
Presqualene diphosphate + NADPH + H+ ⇄ C30 Botryococcene + NADP+ + Diphosphate (1.3.1.97)
NADPH: nadph_c, H+: h_c
Diphosphate + Squalene + NADP+ ⇄ Presqualene diphosphate + NADPH + H+ (1.3.1.96)
Diphosphate: ppi_c, NADP+: nadp_c
2 trans,trans-Farnesyl diphosphate + NADPH + H+ ⇄ Squalene + 2 Diphosphate + NADP+ (2.5.1.21)
trans,trans-Farnesyl diphosphate: frdp_c, NADPH: nadph_c, H+: h_c
S-Adenosyl-L-methionine + C30 Botryococcene ⇄ S-Adenosyl-L-homocysteine + 3-Methyl-1,2-didehydro-2,3-dihydrobotryococcene (2.1.1.263)
S-Adenosyl-L-methionine: amet_c
Presqualene diphosphate + NADPH + H+ ⇄ C30 Botryococcene + NADP+ + Diphosphate (1.3.1.97)
NADPH: nadph_c, H+: h_c
Diphosphate + Squalene + NADP+ ⇄ Presqualene diphosphate + NADPH + H+ (1.3.1.96)
Diphosphate: ppi_c, NADP+: nadp_c
2 trans,trans-Farnesyl diphosphate + NADPH + H+ ⇄ Squalene + 2 Diphosphate + NADP+ (2.5.1.21)
trans,trans-Farnesyl diphosphate: frdp_c, NADPH: nadph_c, H+: h_c
S-Adenosyl-L-methionine + C30 Botryococcene ⇄ S-Adenosyl-L-homocysteine + 20-Methyl-21,22-didehydro-20,21-dihydrobotryococcene (2.1.1.263)
S-Adenosyl-L-methionine: amet_c
Presqualene diphosphate + NADPH + H+ ⇄ C30 Botryococcene + NADP+ + Diphosphate (1.3.1.97)
NADPH: nadph_c, H+: h_c
Diphosphate + Squalene + NADP+ ⇄ Presqualene diphosphate + NADPH + H+ (1.3.1.96)
Diphosphate: ppi_c, NADP+: nadp_c
2 trans,trans-Farnesyl diphosphate + NADPH + H+ ⇄ Squalene + 2 Diphosphate + NADP+ (2.5.1.21)
trans,trans-Farnesyl diphosphate: frdp_c, NADPH: nadph_c, H+: h_c
S-Adenosyl-L-methionine + C30 Botryococcene ⇄ S-Adenosyl-L-homocysteine + 20-Methyl-21,22-didehydro-20,21-dihydrobotryococcene (2.1.1.263)
S-Adenosyl-L-methionine: amet_c
Presqualene diphosphate + NADPH + H+ ⇄ C30 Botryococcene + NADP+ + Diphosphate (1.3.1.97)
NADPH: nadph_c, H+: h_c
Diphosphate + Squalene + NADP+ ⇄ Presqualene diphosphate + NADPH + H+ (1.3.1.96)
Diphosphate: ppi_c, NADP+: nadp_c
2 trans,trans-Farnesyl diphosphate + NADPH + H+ ⇄ Squalene + 2 Diphosphate + NADP+ (2.5.1.21)
trans,trans-Farnesyl diphosphate: frdp_c, NADPH: nadph_c, H+: h_c
2 S-Adenosyl-L-methionine + C30 Botryococcene ⇄ 2 S-Adenosyl-L-homocysteine + 3,20-Dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene (2.1.1.263)
S-Adenosyl-L-methionine: amet_c
Presqualene diphosphate + NADPH + H+ ⇄ C30 Botryococcene + NADP+ + Diphosphate (1.3.1.97)
NADPH: nadph_c, H+: h_c
Diphosphate + Squalene + NADP+ ⇄ Presqualene diphosphate + NADPH + H+ (1.3.1.96)
Diphosphate: ppi_c, NADP+: nadp_c
2 trans,trans-Farnesyl diphosphate + NADPH + H+ ⇄ Squalene + 2 Diphosphate + NADP+ (2.5.1.21)
trans,trans-Farnesyl diphosphate: frdp_c, NADPH: nadph_c, H+: h_c
S-Adenosyl-L-methionine + 3-Methyl-1,2-didehydro-2,3-dihydrobotryococcene ⇄ S-Adenosyl-L-homocysteine + 3,20-Dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene (2.1.1.263)
S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + C30 Botryococcene ⇄ S-Adenosyl-L-homocysteine + 3-Methyl-1,2-didehydro-2,3-dihydrobotryococcene (2.1.1.263)
S-Adenosyl-L-methionine: amet_c
Presqualene diphosphate + NADPH + H+ ⇄ C30 Botryococcene + NADP+ + Diphosphate (1.3.1.97)
NADPH: nadph_c, H+: h_c
Diphosphate + Squalene + NADP+ ⇄ Presqualene diphosphate + NADPH + H+ (1.3.1.96)
Diphosphate: ppi_c, NADP+: nadp_c
2 trans,trans-Farnesyl diphosphate + NADPH + H+ ⇄ Squalene + 2 Diphosphate + NADP+ (2.5.1.21)
trans,trans-Farnesyl diphosphate: frdp_c, NADPH: nadph_c, H+: h_c
S-Adenosyl-L-methionine + 20-Methyl-21,22-didehydro-20,21-dihydrobotryococcene ⇄ S-Adenosyl-L-homocysteine + 3,20-Dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene (2.1.1.263)
S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + C30 Botryococcene ⇄ S-Adenosyl-L-homocysteine + 20-Methyl-21,22-didehydro-20,21-dihydrobotryococcene (2.1.1.263)
S-Adenosyl-L-methionine: amet_c
Presqualene diphosphate + NADPH + H+ ⇄ C30 Botryococcene + NADP+ + Diphosphate (1.3.1.97)
NADPH: nadph_c, H+: h_c
Diphosphate + Squalene + NADP+ ⇄ Presqualene diphosphate + NADPH + H+ (1.3.1.96)
Diphosphate: ppi_c, NADP+: nadp_c
2 trans,trans-Farnesyl diphosphate + NADPH + H+ ⇄ Squalene + 2 Diphosphate + NADP+ (2.5.1.21)
trans,trans-Farnesyl diphosphate: frdp_c, NADPH: nadph_c, H+: h_c
2 S-Adenosyl-L-methionine + C30 Botryococcene ⇄ 2 S-Adenosyl-L-homocysteine + 3,20-Dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene (2.1.1.263)
S-Adenosyl-L-methionine: amet_c
Presqualene diphosphate + NADPH + H+ ⇄ C30 Botryococcene + NADP+ + Diphosphate (1.3.1.97)
NADPH: nadph_c, H+: h_c
Diphosphate + Squalene + NADP+ ⇄ Presqualene diphosphate + NADPH + H+ (1.3.1.96)
Diphosphate: ppi_c, NADP+: nadp_c
2 trans,trans-Farnesyl diphosphate + NADPH + H+ ⇄ Squalene + 2 Diphosphate + NADP+ (2.5.1.21)
trans,trans-Farnesyl diphosphate: frdp_c, NADPH: nadph_c, H+: h_c
S-Adenosyl-L-methionine + 3-Methyl-1,2-didehydro-2,3-dihydrobotryococcene ⇄ S-Adenosyl-L-homocysteine + 3,20-Dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene (2.1.1.263)
S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + C30 Botryococcene ⇄ S-Adenosyl-L-homocysteine + 3-Methyl-1,2-didehydro-2,3-dihydrobotryococcene (2.1.1.263)
S-Adenosyl-L-methionine: amet_c
Presqualene diphosphate + NADPH + H+ ⇄ C30 Botryococcene + NADP+ + Diphosphate (1.3.1.97)
NADPH: nadph_c, H+: h_c
Diphosphate + Squalene + NADP+ ⇄ Presqualene diphosphate + NADPH + H+ (1.3.1.96)
Diphosphate: ppi_c, NADP+: nadp_c
2 trans,trans-Farnesyl diphosphate + NADPH + H+ ⇄ Squalene + 2 Diphosphate + NADP+ (2.5.1.21)
trans,trans-Farnesyl diphosphate: frdp_c, NADPH: nadph_c, H+: h_c
S-Adenosyl-L-methionine + 20-Methyl-21,22-didehydro-20,21-dihydrobotryococcene ⇄ S-Adenosyl-L-homocysteine + 3,20-Dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene (2.1.1.263)
S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + C30 Botryococcene ⇄ S-Adenosyl-L-homocysteine + 20-Methyl-21,22-didehydro-20,21-dihydrobotryococcene (2.1.1.263)
S-Adenosyl-L-methionine: amet_c
Presqualene diphosphate + NADPH + H+ ⇄ C30 Botryococcene + NADP+ + Diphosphate (1.3.1.97)
NADPH: nadph_c, H+: h_c
Diphosphate + Squalene + NADP+ ⇄ Presqualene diphosphate + NADPH + H+ (1.3.1.96)
Diphosphate: ppi_c, NADP+: nadp_c
2 trans,trans-Farnesyl diphosphate + NADPH + H+ ⇄ Squalene + 2 Diphosphate + NADP+ (2.5.1.21)
trans,trans-Farnesyl diphosphate: frdp_c, NADPH: nadph_c, H+: h_c
2 ATP + S-Adenosyl-L-methionine + Anthranilate + L-Phenylalanine ⇄ Cyclopeptine + 2 AMP + 2 Diphosphate + S-Adenosyl-L-homocysteine (6.3.2.40)
S-Adenosyl-L-methionine: amet_c, ATP: atp_c, Anthranilate: anth_c, L-Phenylalanine: phe__L_c
2 ATP + S-Adenosyl-L-methionine + Anthranilate + L-Phenylalanine ⇄ Cyclopeptine + 2 AMP + 2 Diphosphate + S-Adenosyl-L-homocysteine (6.3.2.40)
S-Adenosyl-L-methionine: amet_c, ATP: atp_c, Anthranilate: anth_c, L-Phenylalanine: phe__L_c
GDP-4-dehydro-6-deoxy-D-mannose + L-Glutamate ⇄ GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + 2-Oxoglutarate + Ammonia (4.2.1.168)
L-Glutamate: glu__L_c, GDP-4-dehydro-6-deoxy-D-mannose: gdpddman_c
GDP-4-dehydro-6-deoxy-D-mannose + L-Glutamate ⇄ GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + 2-Oxoglutarate + Ammonia (4.2.1.168)
L-Glutamate: glu__L_c, GDP-4-dehydro-6-deoxy-D-mannose: gdpddman_c
S-Adenosyl-L-methionine + Anthranilate ⇄ S-Adenosyl-L-homocysteine + O-Methyl anthranilate (2.1.1.277)
S-Adenosyl-L-methionine: amet_c, Anthranilate: anth_c
S-Adenosyl-L-methionine + Anthranilate ⇄ S-Adenosyl-L-homocysteine + O-Methyl anthranilate (2.1.1.277)
S-Adenosyl-L-methionine: amet_c, Anthranilate: anth_c
S-Adenosyl-L-methionine + Indole-3-acetate ⇄ S-Adenosyl-L-homocysteine + Methyl (indol-3-yl)acetate (2.1.1.278)
S-Adenosyl-L-methionine: amet_c
Indole-3-acetaldehyde + O2 + H2O ⇄ Indole-3-acetate + Hydrogen peroxide (1.2.3.7)
O2: o2_c, H2O: h2o_c
Indolepyruvate ⇄ Indole-3-acetaldehyde + CO2 (4.1.1.74)
L-Tryptophan + 2-Oxoglutarate ⇄ Indolepyruvate + L-Glutamate (2.6.1.27)
L-Tryptophan: trp__L_c, 2-Oxoglutarate: akg_c
S-Adenosyl-L-methionine + Indole-3-acetate ⇄ S-Adenosyl-L-homocysteine + Methyl (indol-3-yl)acetate (2.1.1.278)
S-Adenosyl-L-methionine: amet_c
Indole-3-acetaldehyde + O2 + H2O ⇄ Indole-3-acetate + Hydrogen peroxide (1.2.3.7)
O2: o2_c, H2O: h2o_c
Indolepyruvate ⇄ Indole-3-acetaldehyde + CO2 (4.1.1.74)
L-Tryptophan + 2-Oxoglutarate ⇄ Indolepyruvate + L-Glutamate (2.6.1.27)
L-Tryptophan: trp__L_c, 2-Oxoglutarate: akg_c
GDP-4-dehydro-6-deoxy-D-mannose + L-Glutamate ⇄ GDP-4-amino-4,6-dideoxy-alpha-D-mannose + 2-Oxoglutarate (2.6.1.102)
L-Glutamate: glu__L_c, GDP-4-dehydro-6-deoxy-D-mannose: gdpddman_c
GDP-4-dehydro-6-deoxy-D-mannose + L-Glutamate ⇄ GDP-4-amino-4,6-dideoxy-alpha-D-mannose + 2-Oxoglutarate (2.6.1.102)
L-Glutamate: glu__L_c, GDP-4-dehydro-6-deoxy-D-mannose: gdpddman_c
S-Adenosyl-L-methionine + Benzoate ⇄ S-Adenosyl-L-homocysteine + Methyl benzoate (2.1.1.273)
S-Adenosyl-L-methionine: amet_c
Benzaldehyde + NADP+ + H2O ⇄ Benzoate + NADPH + H+ (1.2.1.7)
NADP+: nadp_c, H2O: h2o_c
alpha-Oxo-benzeneacetic acid ⇄ Benzaldehyde + CO2 (4.1.1.7)
(R)-Mandelate + NAD+ ⇄ alpha-Oxo-benzeneacetic acid + NADH + H+ (1.1.1.379)
NAD+: nad_c
(S)-Mandelate ⇄ (R)-Mandelate (5.1.2.2)
(S)-4-Hydroxymandelate + 4a-Hydroxy-5,6,7,8-tetrahydropteridine ⇄ (S)-Mandelate + Tetrahydropteridine + O2 (1.14.16.6)
4-Hydroxybenzaldehyde + Hydrogen peroxide + CO2 ⇄ (S)-4-Hydroxymandelate + O2 (1.1.3.19)
Hydrogen peroxide: h2o2_c, CO2: co2_c
4-Hydroxybenzoate + NADH + H+ ⇄ 4-Hydroxybenzaldehyde + NAD+ + H2O (1.2.1.64)
4-Hydroxybenzoate: 4hbz_c, NADH: nadh_c, H+: h_c
L-Phenylalanine + Tetrahydropteridine + O2 ⇄ L-Tyrosine + 4a-Hydroxy-5,6,7,8-tetrahydropteridine (1.14.16.1)
L-Phenylalanine: phe__L_c, Tetrahydropteridine: thptdn_c, O2: o2_c
S-Adenosyl-L-methionine + Benzoate ⇄ S-Adenosyl-L-homocysteine + Methyl benzoate (2.1.1.273)
S-Adenosyl-L-methionine: amet_c
Benzaldehyde + NADP+ + H2O ⇄ Benzoate + NADPH + H+ (1.2.1.7)
NADP+: nadp_c, H2O: h2o_c
alpha-Oxo-benzeneacetic acid ⇄ Benzaldehyde + CO2 (4.1.1.7)
(R)-Mandelate + NAD+ ⇄ alpha-Oxo-benzeneacetic acid + NADH + H+ (1.1.1.379)
NAD+: nad_c
(S)-Mandelate ⇄ (R)-Mandelate (5.1.2.2)
(S)-4-Hydroxymandelate + 4a-Hydroxy-5,6,7,8-tetrahydropteridine ⇄ (S)-Mandelate + Tetrahydropteridine + O2 (1.14.16.6)
4-Hydroxybenzaldehyde + Hydrogen peroxide + CO2 ⇄ (S)-4-Hydroxymandelate + O2 (1.1.3.19)
Hydrogen peroxide: h2o2_c, CO2: co2_c
4-Hydroxybenzoate + NADH + H+ ⇄ 4-Hydroxybenzaldehyde + NAD+ + H2O (1.2.1.64)
4-Hydroxybenzoate: 4hbz_c, NADH: nadh_c, H+: h_c
L-Phenylalanine + Tetrahydropteridine + O2 ⇄ L-Tyrosine + 4a-Hydroxy-5,6,7,8-tetrahydropteridine (1.14.16.1)
L-Phenylalanine: phe__L_c, Tetrahydropteridine: thptdn_c, O2: o2_c
S-Adenosyl-L-methionine + Phenylpyruvate ⇄ S-Adenosyl-L-homocysteine + (3S)-2-Oxo-3-phenylbutanoate (2.1.1.281)
S-Adenosyl-L-methionine: amet_c, Phenylpyruvate: phpyr_c
S-Adenosyl-L-methionine + Phenylpyruvate ⇄ S-Adenosyl-L-homocysteine + (3S)-2-Oxo-3-phenylbutanoate (2.1.1.281)
S-Adenosyl-L-methionine: amet_c, Phenylpyruvate: phpyr_c
S-Adenosyl-L-methionine + 6-Geranylgeranyl-2-methylbenzene-1,4-diol ⇄ S-Adenosyl-L-homocysteine + 6-Geranylgeranyl-2,3-dimethylbenzene-1,4-diol (2.1.1.295)
S-Adenosyl-L-methionine: amet_c
Geranylgeranyl diphosphate + Homogentisate ⇄ Diphosphate + 6-Geranylgeranyl-2-methylbenzene-1,4-diol + CO2 (2.5.1.116)
trans,trans-Farnesyl diphosphate + Isopentenyl diphosphate ⇄ Diphosphate + Geranylgeranyl diphosphate (2.5.1.29)
trans,trans-Farnesyl diphosphate: frdp_c, Isopentenyl diphosphate: ipdp_c
4-Maleylacetoacetate ⇄ Homogentisate + O2 (1.13.11.5)
4-Fumarylacetoacetate ⇄ 4-Maleylacetoacetate (5.2.1.2)
Acetoacetate + Fumarate ⇄ 4-Fumarylacetoacetate + H2O (3.7.1.2)
Acetoacetate: acac_c, Fumarate: fum_c
S-Adenosyl-L-methionine + 6-Geranylgeranyl-2-methylbenzene-1,4-diol ⇄ S-Adenosyl-L-homocysteine + 6-Geranylgeranyl-2,3-dimethylbenzene-1,4-diol (2.1.1.295)
S-Adenosyl-L-methionine: amet_c
Geranylgeranyl diphosphate + Homogentisate ⇄ Diphosphate + 6-Geranylgeranyl-2-methylbenzene-1,4-diol + CO2 (2.5.1.116)
trans,trans-Farnesyl diphosphate + Isopentenyl diphosphate ⇄ Diphosphate + Geranylgeranyl diphosphate (2.5.1.29)
trans,trans-Farnesyl diphosphate: frdp_c, Isopentenyl diphosphate: ipdp_c
4-Maleylacetoacetate ⇄ Homogentisate + O2 (1.13.11.5)
4-Fumarylacetoacetate ⇄ 4-Maleylacetoacetate (5.2.1.2)
Acetoacetate + Fumarate ⇄ 4-Fumarylacetoacetate + H2O (3.7.1.2)
Acetoacetate: acac_c, Fumarate: fum_c
S-Adenosyl-L-methionine + L-Tyrosine ⇄ S-Adenosyl-L-homocysteine + 3-Methyl-L-tyrosine (2.1.1.304)
S-Adenosyl-L-methionine: amet_c, L-Tyrosine: tyr__L_c
S-Adenosyl-L-methionine + L-Tyrosine ⇄ S-Adenosyl-L-homocysteine + 3-Methyl-L-tyrosine (2.1.1.304)
S-Adenosyl-L-methionine: amet_c, L-Tyrosine: tyr__L_c
(3S)-2-Oxo-3-phenylbutanoate + L-Glutamate ⇄ (2S,3S)-3-Methylphenylalanine + 2-Oxoglutarate (2.6.1.107)
L-Glutamate: glu__L_c
S-Adenosyl-L-methionine + Phenylpyruvate ⇄ S-Adenosyl-L-homocysteine + (3S)-2-Oxo-3-phenylbutanoate (2.1.1.281)
S-Adenosyl-L-methionine: amet_c, Phenylpyruvate: phpyr_c
(3S)-2-Oxo-3-phenylbutanoate + L-Glutamate ⇄ (2S,3S)-3-Methylphenylalanine + 2-Oxoglutarate (2.6.1.107)
L-Glutamate: glu__L_c
S-Adenosyl-L-methionine + Phenylpyruvate ⇄ S-Adenosyl-L-homocysteine + (3S)-2-Oxo-3-phenylbutanoate (2.1.1.281)
S-Adenosyl-L-methionine: amet_c, Phenylpyruvate: phpyr_c
S-Adenosyl-L-methionine + 3-Hydroxy-5-methyl-1-naphthoate ⇄ S-Adenosyl-L-homocysteine + 3-Methoxy-5-methyl-1-naphthoate (2.1.1.302)
S-Adenosyl-L-methionine: amet_c
5-Methyl-1-naphthoate + NADPH + H+ + O2 ⇄ 3-Hydroxy-5-methyl-1-naphthoate + NADP+ + H2O (1.14.13.189)
NADPH: nadph_c, H+: h_c, O2: o2_c
Acetyl-CoA + 5 Malonyl-CoA + 3 NADPH + 3 H+ ⇄ 5-Methyl-1-naphthoate + 6 CoA + 5 CO2 + 4 H2O + 3 NADP+ (2.3.1.236)
Acetyl-CoA: accoa_c, Malonyl-CoA: malcoa_c, NADPH: nadph_c, H+: h_c
S-Adenosyl-L-methionine + 3-Hydroxy-5-methyl-1-naphthoate ⇄ S-Adenosyl-L-homocysteine + 3-Methoxy-5-methyl-1-naphthoate (2.1.1.302)
S-Adenosyl-L-methionine: amet_c
5-Methyl-1-naphthoate + NADPH + H+ + O2 ⇄ 3-Hydroxy-5-methyl-1-naphthoate + NADP+ + H2O (1.14.13.189)
NADPH: nadph_c, H+: h_c, O2: o2_c
Acetyl-CoA + 5 Malonyl-CoA + 3 NADPH + 3 H+ ⇄ 5-Methyl-1-naphthoate + 6 CoA + 5 CO2 + 4 H2O + 3 NADP+ (2.3.1.236)
Acetyl-CoA: accoa_c, Malonyl-CoA: malcoa_c, NADPH: nadph_c, H+: h_c
(5-Formylfuran-3-yl)methyl phosphate + L-Alanine ⇄ [5-(Aminomethyl)furan-3-yl]methyl phosphate + Pyruvate (2.6.1.108)
L-Alanine: ala__L_c
2 D-Glyceraldehyde 3-phosphate ⇄ (5-Formylfuran-3-yl)methyl phosphate + Orthophosphate + 2 H2O (4.2.3.153)
D-Glyceraldehyde 3-phosphate: g3p_c
(5-Formylfuran-3-yl)methyl phosphate + L-Alanine ⇄ [5-(Aminomethyl)furan-3-yl]methyl phosphate + Pyruvate (2.6.1.108)
L-Alanine: ala__L_c
2 D-Glyceraldehyde 3-phosphate ⇄ (5-Formylfuran-3-yl)methyl phosphate + Orthophosphate + 2 H2O (4.2.3.153)
D-Glyceraldehyde 3-phosphate: g3p_c
9 Malonyl-CoA + 11 NADPH + 10 H+ + S-Adenosyl-L-methionine + Acyl-carrier protein ⇄ Dihydromonacolin L-[acyl-carrier protein] + 9 CoA + 9 CO2 + 11 NADP+ + S-Adenosyl-L-homocysteine + 6 H2O (2.3.1.161)
S-Adenosyl-L-methionine: amet_c, Malonyl-CoA: malcoa_c, NADPH: nadph_c, H+: h_c, Acyl-carrier protein: ACP_c
9 Malonyl-CoA + 11 NADPH + 10 H+ + S-Adenosyl-L-methionine + Acyl-carrier protein ⇄ Dihydromonacolin L-[acyl-carrier protein] + 9 CoA + 9 CO2 + 11 NADP+ + S-Adenosyl-L-homocysteine + 6 H2O (2.3.1.161)
S-Adenosyl-L-methionine: amet_c, Malonyl-CoA: malcoa_c, NADPH: nadph_c, H+: h_c, Acyl-carrier protein: ACP_c
2 Malonyl-CoA + Acyl-carrier protein + 2 NADPH + 2 H+ + S-Adenosyl-L-methionine ⇄ (S)-2-Methylbutanoyl-[acp] + 2 CoA + 2 CO2 + 2 NADP+ + S-Adenosyl-L-homocysteine + H2O (2.3.1.244)
S-Adenosyl-L-methionine: amet_c, Malonyl-CoA: malcoa_c, Acyl-carrier protein: ACP_c, NADPH: nadph_c, H+: h_c
2 Malonyl-CoA + Acyl-carrier protein + 2 NADPH + 2 H+ + S-Adenosyl-L-methionine ⇄ (S)-2-Methylbutanoyl-[acp] + 2 CoA + 2 CO2 + 2 NADP+ + S-Adenosyl-L-homocysteine + H2O (2.3.1.244)
S-Adenosyl-L-methionine: amet_c, Malonyl-CoA: malcoa_c, Acyl-carrier protein: ACP_c, NADPH: nadph_c, H+: h_c
S-Adenosyl-L-methionine + Indolepyruvate ⇄ S-Adenosyl-L-homocysteine + (R)-3-(Indol-3-yl)-2-oxobutyrate (2.1.1.47)
S-Adenosyl-L-methionine: amet_c
L-Tryptophan + 2-Oxoglutarate ⇄ Indolepyruvate + L-Glutamate (2.6.1.27)
L-Tryptophan: trp__L_c, 2-Oxoglutarate: akg_c
S-Adenosyl-L-methionine + Indolepyruvate ⇄ S-Adenosyl-L-homocysteine + (R)-3-(Indol-3-yl)-2-oxobutyrate (2.1.1.47)
S-Adenosyl-L-methionine: amet_c
L-Tryptophan + 2-Oxoglutarate ⇄ Indolepyruvate + L-Glutamate (2.6.1.27)
L-Tryptophan: trp__L_c, 2-Oxoglutarate: akg_c
8-Ethyl-12-methyl-3-vinylbacteriochlorophyllide d + S-Adenosyl-L-methionine ⇄ 8,12-Diethyl-3-vinylbacteriochlorophyllide d + S-Adenosyl-L-homocysteine (2.1.1.331)
S-Adenosyl-L-methionine: amet_c
Chlorophyllide + H2O ⇄ 8-Ethyl-12-methyl-3-vinylbacteriochlorophyllide d + Methanol + CO2 (3.1.1.100)
H2O: h2o_c
Protochlorophyllide + NADPH + H+ ⇄ Chlorophyllide + NADP+ (1.3.1.33)
NADPH: nadph_c, H+: h_c
Divinylprotochlorophyllide + NADPH + H+ ⇄ Protochlorophyllide + NADP+ (1.3.1.75)
NADPH: nadph_c, H+: h_c
Magnesium protoporphyrin monomethyl ester + 3 NADPH + 3 H+ + 3 O2 ⇄ Divinylprotochlorophyllide + 3 NADP+ + 5 H2O (1.14.13.81)
NADPH: nadph_c, H+: h_c, O2: o2_c
S-Adenosyl-L-methionine + Magnesium protoporphyrin ⇄ S-Adenosyl-L-homocysteine + Magnesium protoporphyrin monomethyl ester (2.1.1.11)
S-Adenosyl-L-methionine: amet_c
ATP + Protoporphyrin + Magnesium cation + H2O ⇄ ADP + Orthophosphate + Magnesium protoporphyrin + 2 H+ (6.6.1.1)
ATP: atp_c, Protoporphyrin: ppp9_c, Magnesium cation: mg2_c, H2O: h2o_c
8-Ethyl-12-methyl-3-vinylbacteriochlorophyllide d + S-Adenosyl-L-methionine ⇄ 8,12-Diethyl-3-vinylbacteriochlorophyllide d + S-Adenosyl-L-homocysteine (2.1.1.331)
S-Adenosyl-L-methionine: amet_c
Chlorophyllide + H2O ⇄ 8-Ethyl-12-methyl-3-vinylbacteriochlorophyllide d + Methanol + CO2 (3.1.1.100)
H2O: h2o_c
Protochlorophyllide + NADPH + H+ ⇄ Chlorophyllide + NADP+ (1.3.1.33)
NADPH: nadph_c, H+: h_c
Divinylprotochlorophyllide + NADPH + H+ ⇄ Protochlorophyllide + NADP+ (1.3.1.75)
NADPH: nadph_c, H+: h_c
Magnesium protoporphyrin monomethyl ester + 3 NADPH + 3 H+ + 3 O2 ⇄ Divinylprotochlorophyllide + 3 NADP+ + 5 H2O (1.14.13.81)
NADPH: nadph_c, H+: h_c, O2: o2_c
S-Adenosyl-L-methionine + Magnesium protoporphyrin ⇄ S-Adenosyl-L-homocysteine + Magnesium protoporphyrin monomethyl ester (2.1.1.11)
S-Adenosyl-L-methionine: amet_c
ATP + Protoporphyrin + Magnesium cation + H2O ⇄ ADP + Orthophosphate + Magnesium protoporphyrin + 2 H+ (6.6.1.1)
ATP: atp_c, Protoporphyrin: ppp9_c, Magnesium cation: mg2_c, H2O: h2o_c
8,12-Diethyl-3-vinylbacteriochlorophyllide d + S-Adenosyl-L-methionine ⇄ 12-Ethyl-8-propyl-3-vinylbacteriochlorophyllide d + S-Adenosyl-L-homocysteine (2.1.1.332)
S-Adenosyl-L-methionine: amet_c
8-Ethyl-12-methyl-3-vinylbacteriochlorophyllide d + S-Adenosyl-L-methionine ⇄ 8,12-Diethyl-3-vinylbacteriochlorophyllide d + S-Adenosyl-L-homocysteine (2.1.1.331)
S-Adenosyl-L-methionine: amet_c
Chlorophyllide + H2O ⇄ 8-Ethyl-12-methyl-3-vinylbacteriochlorophyllide d + Methanol + CO2 (3.1.1.100)
H2O: h2o_c
Protochlorophyllide + NADPH + H+ ⇄ Chlorophyllide + NADP+ (1.3.1.33)
NADPH: nadph_c, H+: h_c
Divinylprotochlorophyllide + NADPH + H+ ⇄ Protochlorophyllide + NADP+ (1.3.1.75)
NADPH: nadph_c, H+: h_c
Magnesium protoporphyrin monomethyl ester + 3 NADPH + 3 H+ + 3 O2 ⇄ Divinylprotochlorophyllide + 3 NADP+ + 5 H2O (1.14.13.81)
NADPH: nadph_c, H+: h_c, O2: o2_c
S-Adenosyl-L-methionine + Magnesium protoporphyrin ⇄ S-Adenosyl-L-homocysteine + Magnesium protoporphyrin monomethyl ester (2.1.1.11)
S-Adenosyl-L-methionine: amet_c
ATP + Protoporphyrin + Magnesium cation + H2O ⇄ ADP + Orthophosphate + Magnesium protoporphyrin + 2 H+ (6.6.1.1)
ATP: atp_c, Protoporphyrin: ppp9_c, Magnesium cation: mg2_c, H2O: h2o_c
8,12-Diethyl-3-vinylbacteriochlorophyllide d + S-Adenosyl-L-methionine ⇄ 12-Ethyl-8-propyl-3-vinylbacteriochlorophyllide d + S-Adenosyl-L-homocysteine (2.1.1.332)
S-Adenosyl-L-methionine: amet_c
8-Ethyl-12-methyl-3-vinylbacteriochlorophyllide d + S-Adenosyl-L-methionine ⇄ 8,12-Diethyl-3-vinylbacteriochlorophyllide d + S-Adenosyl-L-homocysteine (2.1.1.331)
S-Adenosyl-L-methionine: amet_c
Chlorophyllide + H2O ⇄ 8-Ethyl-12-methyl-3-vinylbacteriochlorophyllide d + Methanol + CO2 (3.1.1.100)
H2O: h2o_c
Protochlorophyllide + NADPH + H+ ⇄ Chlorophyllide + NADP+ (1.3.1.33)
NADPH: nadph_c, H+: h_c
Divinylprotochlorophyllide + NADPH + H+ ⇄ Protochlorophyllide + NADP+ (1.3.1.75)
NADPH: nadph_c, H+: h_c
Magnesium protoporphyrin monomethyl ester + 3 NADPH + 3 H+ + 3 O2 ⇄ Divinylprotochlorophyllide + 3 NADP+ + 5 H2O (1.14.13.81)
NADPH: nadph_c, H+: h_c, O2: o2_c
S-Adenosyl-L-methionine + Magnesium protoporphyrin ⇄ S-Adenosyl-L-homocysteine + Magnesium protoporphyrin monomethyl ester (2.1.1.11)
S-Adenosyl-L-methionine: amet_c
ATP + Protoporphyrin + Magnesium cation + H2O ⇄ ADP + Orthophosphate + Magnesium protoporphyrin + 2 H+ (6.6.1.1)
ATP: atp_c, Protoporphyrin: ppp9_c, Magnesium cation: mg2_c, H2O: h2o_c
S-Adenosyl-L-methionine + Ornithine lipid ⇄ S-Adenosyl-L-homocysteine + N-Methylornithine lipid (2.1.1.344)
S-Adenosyl-L-methionine: amet_c
Lyso-ornithine lipid + Acyl-[acyl-carrier protein] ⇄ Ornithine lipid + Acyl-carrier protein (2.3.1.270)
L-Ornithine + (3R)-3-Hydroxyacyl-[acyl-carrier protein] ⇄ Lyso-ornithine lipid + Acyl-carrier protein (2.3.2.30)
L-Ornithine: orn_c, (3R)-3-Hydroxyacyl-[acyl-carrier protein]: 3haACP_c
trans-2,3-Dehydroacyl-[acyl-carrier protein] + NADH + H+ ⇄ Acyl-[acyl-carrier protein] + NAD+ (1.3.1.9)
NADH: nadh_c, H+: h_c
(3R)-3-Hydroxyacyl-[acyl-carrier protein] ⇄ trans-2,3-Dehydroacyl-[acyl-carrier protein] + H2O (4.2.1.59)
(3R)-3-Hydroxyacyl-[acyl-carrier protein]: 3haACP_c
S-Adenosyl-L-methionine + Ornithine lipid ⇄ S-Adenosyl-L-homocysteine + N-Methylornithine lipid (2.1.1.344)
S-Adenosyl-L-methionine: amet_c
Lyso-ornithine lipid + Acyl-[acyl-carrier protein] ⇄ Ornithine lipid + Acyl-carrier protein (2.3.1.270)
L-Ornithine + (3R)-3-Hydroxyacyl-[acyl-carrier protein] ⇄ Lyso-ornithine lipid + Acyl-carrier protein (2.3.2.30)
L-Ornithine: orn_c, (3R)-3-Hydroxyacyl-[acyl-carrier protein]: 3haACP_c
trans-2,3-Dehydroacyl-[acyl-carrier protein] + NADH + H+ ⇄ Acyl-[acyl-carrier protein] + NAD+ (1.3.1.9)
NADH: nadh_c, H+: h_c
(3R)-3-Hydroxyacyl-[acyl-carrier protein] ⇄ trans-2,3-Dehydroacyl-[acyl-carrier protein] + H2O (4.2.1.59)
(3R)-3-Hydroxyacyl-[acyl-carrier protein]: 3haACP_c
S-Adenosyl-L-methionine + N-Methylornithine lipid ⇄ S-Adenosyl-L-homocysteine + N,N-Dimethylornithine lipid (2.1.1.344)
S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + Ornithine lipid ⇄ S-Adenosyl-L-homocysteine + N-Methylornithine lipid (2.1.1.344)
S-Adenosyl-L-methionine: amet_c
Lyso-ornithine lipid + Acyl-[acyl-carrier protein] ⇄ Ornithine lipid + Acyl-carrier protein (2.3.1.270)
L-Ornithine + (3R)-3-Hydroxyacyl-[acyl-carrier protein] ⇄ Lyso-ornithine lipid + Acyl-carrier protein (2.3.2.30)
L-Ornithine: orn_c, (3R)-3-Hydroxyacyl-[acyl-carrier protein]: 3haACP_c
trans-2,3-Dehydroacyl-[acyl-carrier protein] + NADH + H+ ⇄ Acyl-[acyl-carrier protein] + NAD+ (1.3.1.9)
NADH: nadh_c, H+: h_c
(3R)-3-Hydroxyacyl-[acyl-carrier protein] ⇄ trans-2,3-Dehydroacyl-[acyl-carrier protein] + H2O (4.2.1.59)
(3R)-3-Hydroxyacyl-[acyl-carrier protein]: 3haACP_c
S-Adenosyl-L-methionine + N-Methylornithine lipid ⇄ S-Adenosyl-L-homocysteine + N,N-Dimethylornithine lipid (2.1.1.344)
S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + Ornithine lipid ⇄ S-Adenosyl-L-homocysteine + N-Methylornithine lipid (2.1.1.344)
S-Adenosyl-L-methionine: amet_c
Lyso-ornithine lipid + Acyl-[acyl-carrier protein] ⇄ Ornithine lipid + Acyl-carrier protein (2.3.1.270)
L-Ornithine + (3R)-3-Hydroxyacyl-[acyl-carrier protein] ⇄ Lyso-ornithine lipid + Acyl-carrier protein (2.3.2.30)
L-Ornithine: orn_c, (3R)-3-Hydroxyacyl-[acyl-carrier protein]: 3haACP_c
trans-2,3-Dehydroacyl-[acyl-carrier protein] + NADH + H+ ⇄ Acyl-[acyl-carrier protein] + NAD+ (1.3.1.9)
NADH: nadh_c, H+: h_c
(3R)-3-Hydroxyacyl-[acyl-carrier protein] ⇄ trans-2,3-Dehydroacyl-[acyl-carrier protein] + H2O (4.2.1.59)
(3R)-3-Hydroxyacyl-[acyl-carrier protein]: 3haACP_c
3 S-Adenosyl-L-methionine + Ornithine lipid ⇄ 3 S-Adenosyl-L-homocysteine + N,N,N-Trimethylornithine lipid (2.1.1.344)
S-Adenosyl-L-methionine: amet_c
Lyso-ornithine lipid + Acyl-[acyl-carrier protein] ⇄ Ornithine lipid + Acyl-carrier protein (2.3.1.270)
L-Ornithine + (3R)-3-Hydroxyacyl-[acyl-carrier protein] ⇄ Lyso-ornithine lipid + Acyl-carrier protein (2.3.2.30)
L-Ornithine: orn_c, (3R)-3-Hydroxyacyl-[acyl-carrier protein]: 3haACP_c
trans-2,3-Dehydroacyl-[acyl-carrier protein] + NADH + H+ ⇄ Acyl-[acyl-carrier protein] + NAD+ (1.3.1.9)
NADH: nadh_c, H+: h_c
(3R)-3-Hydroxyacyl-[acyl-carrier protein] ⇄ trans-2,3-Dehydroacyl-[acyl-carrier protein] + H2O (4.2.1.59)
(3R)-3-Hydroxyacyl-[acyl-carrier protein]: 3haACP_c
S-Adenosyl-L-methionine + N,N-Dimethylornithine lipid ⇄ S-Adenosyl-L-homocysteine + N,N,N-Trimethylornithine lipid (2.1.1.344)
S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + N-Methylornithine lipid ⇄ S-Adenosyl-L-homocysteine + N,N-Dimethylornithine lipid (2.1.1.344)
S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + Ornithine lipid ⇄ S-Adenosyl-L-homocysteine + N-Methylornithine lipid (2.1.1.344)
S-Adenosyl-L-methionine: amet_c
Lyso-ornithine lipid + Acyl-[acyl-carrier protein] ⇄ Ornithine lipid + Acyl-carrier protein (2.3.1.270)
L-Ornithine + (3R)-3-Hydroxyacyl-[acyl-carrier protein] ⇄ Lyso-ornithine lipid + Acyl-carrier protein (2.3.2.30)
L-Ornithine: orn_c, (3R)-3-Hydroxyacyl-[acyl-carrier protein]: 3haACP_c
trans-2,3-Dehydroacyl-[acyl-carrier protein] + NADH + H+ ⇄ Acyl-[acyl-carrier protein] + NAD+ (1.3.1.9)
NADH: nadh_c, H+: h_c
(3R)-3-Hydroxyacyl-[acyl-carrier protein] ⇄ trans-2,3-Dehydroacyl-[acyl-carrier protein] + H2O (4.2.1.59)
(3R)-3-Hydroxyacyl-[acyl-carrier protein]: 3haACP_c
3 S-Adenosyl-L-methionine + Ornithine lipid ⇄ 3 S-Adenosyl-L-homocysteine + N,N,N-Trimethylornithine lipid (2.1.1.344)
S-Adenosyl-L-methionine: amet_c
Lyso-ornithine lipid + Acyl-[acyl-carrier protein] ⇄ Ornithine lipid + Acyl-carrier protein (2.3.1.270)
L-Ornithine + (3R)-3-Hydroxyacyl-[acyl-carrier protein] ⇄ Lyso-ornithine lipid + Acyl-carrier protein (2.3.2.30)
L-Ornithine: orn_c, (3R)-3-Hydroxyacyl-[acyl-carrier protein]: 3haACP_c
trans-2,3-Dehydroacyl-[acyl-carrier protein] + NADH + H+ ⇄ Acyl-[acyl-carrier protein] + NAD+ (1.3.1.9)
NADH: nadh_c, H+: h_c
(3R)-3-Hydroxyacyl-[acyl-carrier protein] ⇄ trans-2,3-Dehydroacyl-[acyl-carrier protein] + H2O (4.2.1.59)
(3R)-3-Hydroxyacyl-[acyl-carrier protein]: 3haACP_c
S-Adenosyl-L-methionine + N,N-Dimethylornithine lipid ⇄ S-Adenosyl-L-homocysteine + N,N,N-Trimethylornithine lipid (2.1.1.344)
S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + N-Methylornithine lipid ⇄ S-Adenosyl-L-homocysteine + N,N-Dimethylornithine lipid (2.1.1.344)
S-Adenosyl-L-methionine: amet_c
S-Adenosyl-L-methionine + Ornithine lipid ⇄ S-Adenosyl-L-homocysteine + N-Methylornithine lipid (2.1.1.344)
S-Adenosyl-L-methionine: amet_c
Lyso-ornithine lipid + Acyl-[acyl-carrier protein] ⇄ Ornithine lipid + Acyl-carrier protein (2.3.1.270)
L-Ornithine + (3R)-3-Hydroxyacyl-[acyl-carrier protein] ⇄ Lyso-ornithine lipid + Acyl-carrier protein (2.3.2.30)
L-Ornithine: orn_c, (3R)-3-Hydroxyacyl-[acyl-carrier protein]: 3haACP_c
trans-2,3-Dehydroacyl-[acyl-carrier protein] + NADH + H+ ⇄ Acyl-[acyl-carrier protein] + NAD+ (1.3.1.9)
NADH: nadh_c, H+: h_c
(3R)-3-Hydroxyacyl-[acyl-carrier protein] ⇄ trans-2,3-Dehydroacyl-[acyl-carrier protein] + H2O (4.2.1.59)
(3R)-3-Hydroxyacyl-[acyl-carrier protein]: 3haACP_c
S-Adenosyl-L-methionine + (+)-Kolavelool ⇄ S-Adenosyl-L-homocysteine + (+)-O-Methylkolavelool (2.1.1.347)
S-Adenosyl-L-methionine: amet_c
(+)-Kolavenyl diphosphate + H2O ⇄ (+)-Kolavelool + Diphosphate (3.1.7.12)
H2O: h2o_c
Geranylgeranyl diphosphate ⇄ (+)-Kolavenyl diphosphate (5.5.1.29)
trans,trans-Farnesyl diphosphate + Isopentenyl diphosphate ⇄ Diphosphate + Geranylgeranyl diphosphate (2.5.1.29)
trans,trans-Farnesyl diphosphate: frdp_c, Isopentenyl diphosphate: ipdp_c
S-Adenosyl-L-methionine + (+)-Kolavelool ⇄ S-Adenosyl-L-homocysteine + (+)-O-Methylkolavelool (2.1.1.347)
S-Adenosyl-L-methionine: amet_c
(+)-Kolavenyl diphosphate + H2O ⇄ (+)-Kolavelool + Diphosphate (3.1.7.12)
H2O: h2o_c
Geranylgeranyl diphosphate ⇄ (+)-Kolavenyl diphosphate (5.5.1.29)
trans,trans-Farnesyl diphosphate + Isopentenyl diphosphate ⇄ Diphosphate + Geranylgeranyl diphosphate (2.5.1.29)
trans,trans-Farnesyl diphosphate: frdp_c, Isopentenyl diphosphate: ipdp_c
5-Amino-6-(1-D-ribitylamino)uracil + L-Tyrosine + S-Adenosyl-L-methionine ⇄ 5-Amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + Iminoglycine + L-Methionine + 5'-Deoxyadenosine (2.5.1.147)
S-Adenosyl-L-methionine: amet_c, 5-Amino-6-(1-D-ribitylamino)uracil: 4r5au_c, L-Tyrosine: tyr__L_c
5-Amino-6-(1-D-ribitylamino)uracil + L-Tyrosine + S-Adenosyl-L-methionine ⇄ 5-Amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + Iminoglycine + L-Methionine + 5'-Deoxyadenosine (2.5.1.147)
S-Adenosyl-L-methionine: amet_c, 5-Amino-6-(1-D-ribitylamino)uracil: 4r5au_c, L-Tyrosine: tyr__L_c
(2E,5S,6E,8E,10E)-5-Hydroxydodeca-2,6,8,10-tetraenal + L-Alanine ⇄ (2E,5S,6E,8E,10E)-1-Aminododeca-2,6,8,10-tetraen-5-ol + Pyruvate (2.6.1.115)
L-Alanine: ala__L_c
6 Malonyl-CoA + 5 NADPH + NADH + 6 H+ ⇄ (2E,5S,6E,8E,10E)-5-Hydroxydodeca-2,6,8,10-tetraenal + 6 CoA + 5 NADP+ + NAD+ + 6 CO2 + 4 H2O (2.3.1.281)
Malonyl-CoA: malcoa_c, NADPH: nadph_c, NADH: nadh_c, H+: h_c
(2E,5S,6E,8E,10E)-5-Hydroxydodeca-2,6,8,10-tetraenal + L-Alanine ⇄ (2E,5S,6E,8E,10E)-1-Aminododeca-2,6,8,10-tetraen-5-ol + Pyruvate (2.6.1.115)
L-Alanine: ala__L_c
6 Malonyl-CoA + 5 NADPH + NADH + 6 H+ ⇄ (2E,5S,6E,8E,10E)-5-Hydroxydodeca-2,6,8,10-tetraenal + 6 CoA + 5 NADP+ + NAD+ + 6 CO2 + 4 H2O (2.3.1.281)
Malonyl-CoA: malcoa_c, NADPH: nadph_c, NADH: nadh_c, H+: h_c
S-Adenosyl-L-methionine + trans,trans-Farnesyl diphosphate ⇄ S-Adenosyl-L-homocysteine + Pre-sodorifen diphosphate (2.1.1.363)
S-Adenosyl-L-methionine: amet_c, trans,trans-Farnesyl diphosphate: frdp_c
S-Adenosyl-L-methionine + trans,trans-Farnesyl diphosphate ⇄ S-Adenosyl-L-homocysteine + Pre-sodorifen diphosphate (2.1.1.363)
S-Adenosyl-L-methionine: amet_c, trans,trans-Farnesyl diphosphate: frdp_c
S-Adenosyl-L-methionine + 3-Amino-2,4-dihydroxybenzoate ⇄ S-Adenosyl-L-homocysteine + 3-Amino-2-hydroxy-4-methoxybenzoate (2.1.1.380)
S-Adenosyl-L-methionine: amet_c
3-Amino-4-hydroxybenzoate + NADPH + H+ + O2 ⇄ 3-Amino-2,4-dihydroxybenzoate + NADP+ + H2O (1.14.13.249)
NADPH: nadph_c, H+: h_c, O2: o2_c
2-Amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate ⇄ 3-Amino-4-hydroxybenzoate + Orthophosphate + 2 H2O (4.1.99.20)
Glycerone phosphate + L-Aspartate 4-semialdehyde ⇄ 2-Amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate (4.1.2.56)
Glycerone phosphate: dhap_c, L-Aspartate 4-semialdehyde: aspsa_c
S-Adenosyl-L-methionine + 3-Amino-2,4-dihydroxybenzoate ⇄ S-Adenosyl-L-homocysteine + 3-Amino-2-hydroxy-4-methoxybenzoate (2.1.1.380)
S-Adenosyl-L-methionine: amet_c
3-Amino-4-hydroxybenzoate + NADPH + H+ + O2 ⇄ 3-Amino-2,4-dihydroxybenzoate + NADP+ + H2O (1.14.13.249)
NADPH: nadph_c, H+: h_c, O2: o2_c
2-Amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate ⇄ 3-Amino-4-hydroxybenzoate + Orthophosphate + 2 H2O (4.1.99.20)
Glycerone phosphate + L-Aspartate 4-semialdehyde ⇄ 2-Amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate (4.1.2.56)
Glycerone phosphate: dhap_c, L-Aspartate 4-semialdehyde: aspsa_c
UDP-2-acetamido-3-dehydro-2-deoxy-alpha-D-glucopyranose + L-Glutamate ⇄ UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose + 2-Oxoglutarate (2.6.1.122)
L-Glutamate: glu__L_c
UDP-N-acetyl-alpha-D-glucosamine + NAD+ ⇄ UDP-2-acetamido-3-dehydro-2-deoxy-alpha-D-glucopyranose + NADH + H+ (1.1.1.374)
UDP-N-acetyl-alpha-D-glucosamine: uacgam_c, NAD+: nad_c
UDP-2-acetamido-3-dehydro-2-deoxy-alpha-D-glucopyranose + L-Glutamate ⇄ UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose + 2-Oxoglutarate (2.6.1.122)
L-Glutamate: glu__L_c
UDP-N-acetyl-alpha-D-glucosamine + NAD+ ⇄ UDP-2-acetamido-3-dehydro-2-deoxy-alpha-D-glucopyranose + NADH + H+ (1.1.1.374)
UDP-N-acetyl-alpha-D-glucosamine: uacgam_c, NAD+: nad_c