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paper/paper.bib

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@@ -57,3 +57,34 @@ @ARTICLE{MacKay1994-aj
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year = 1994,
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language = "en"
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}
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@ARTICLE{Hennig1988-qh,
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title = "Multiecho imaging sequences with low refocusing flip angles",
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author = "Hennig, J",
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abstract = "A simple algorithm is presented, which permits recognition of all
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echos occurring in periodic multipulse sequences. The calculated
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and observed signal amplitudes are considerably higher than
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expected from primary echo formation alone. T2 relaxation time
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measurements neglecting the formation of stimulated and indirect
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echoes lead to erroneous results. A method is demonstrated for a
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T2-sensitive multiecho experiment. A RARE experiment based on
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these principles delivers sufficient signal intensity even with
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small refocusing flip angles.",
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journal = "J. Magn. Reson.",
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volume = 78,
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number = 3,
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pages = "397--407",
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month = jul,
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year = 1988
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}
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@ARTICLE{Prasloski2012-vi,
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title = "Applications of stimulated echo correction to multicomponent
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T2 analysis",
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author = "Prasloski, T and Madler, B and Xiang, Q-S and MacKay, A and
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Jones, C",
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journal = "Magn. Reson. Med.",
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year = 2012
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}

paper/paper.md

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@@ -21,7 +21,7 @@ bibliography: paper.bib
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# Summary
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Magnetic resonance imaging (MRI) is a common imaging technique to evaluate, assess, and diagnose diseases throughout the body. One of the most common MRI sequences is a T2 sequence which is sensitive to changes in the brain due to disease processes, for example multiple sclerosis (MS). In MS, the disease breaks down the myelin surrounding the neurons [@Dobson2019-eh] resulting in disability for the patient. Myelin water imaging [@MacKay1994-aj] is one technique to quantify the myelin water in the brain to assess the degree of disease and is based on a multi-echo T2 decay curve. This T2 decay curve is fit and the short T2 component has been shown to be related to myelin.
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Magnetic resonance imaging (MRI) is a common imaging technique to evaluate, assess, and diagnose diseases throughout the body. One of the most common MRI sequences is a T2 sequence which is sensitive to changes in the brain due to disease processes, for example multiple sclerosis (MS). In MS, the disease breaks down the myelin surrounding the neurons resulting in disability for the patient. Myelin water imaging is one technique to quantify the myelin water in the brain to assess the degree of disease and is based on a multi-echo T2 decay curve. This T2 decay curve is fit and the short T2 component has been shown to be related to myelin.
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# Statement of need
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