diff --git a/python_dependencies/processing/requirements.txt b/python_dependencies/processing/requirements.txt
index 8198d341ee3b3..533b292d51e7d 100644
--- a/python_dependencies/processing/requirements.txt
+++ b/python_dependencies/processing/requirements.txt
@@ -20,7 +20,7 @@ pydantic>=1.9.0
 PyMySQL==0.9.3
 python-json-logger
 requests>=2.22.0
-rpy2==3.5.14
+rpy2==3.5.16
 rsa>=4.7 # not directly required, pinned by Snyk to avoid a vulnerability
 s3fs==0.4.2
 scanpy==1.9.3