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DESCRIPTION
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Package: ldsep
Title: Linkage Disequilibrium Shrinkage Estimation for Polyploids
Version: 2.1.5
Authors@R:
person(given = "David",
family = "Gerard",
role = c("aut", "cre"),
email = "gerard.1787@gmail.com",
comment = c(ORCID = "0000-0001-9450-5023"))
Description: Estimate haplotypic or composite pairwise linkage disequilibrium
(LD) in polyploids, using either genotypes or genotype likelihoods.
Support is provided to estimate the popular measures of LD: the LD
coefficient D, the standardized LD coefficient D', and the Pearson
correlation coefficient r. All estimates are returned with corresponding
standard errors. These estimates and standard errors can then be used
for shrinkage estimation. The main functions are ldfast(), ldest(), mldest(),
sldest(), plot.lddf(), format_lddf(), and ldshrink(). Details of the methods
are available in Gerard (2021a) <doi:10.1111/1755-0998.13349>
and Gerard (2021b) <doi:10.1038/s41437-021-00462-5>.
License: GPL-3
BugReports: https://github.com/dcgerard/ldsep/issues
Encoding: UTF-8
LazyData: true
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.2.1
LinkingTo:
Rcpp,
RcppArmadillo
Imports:
Rcpp,
foreach,
doParallel,
ashr,
corrplot,
lpSolve,
abind,
modeest,
matrixStats
Suggests:
testthat,
covr,
knitr,
rmarkdown,
updog (>= 2.0.2),
VariantAnnotation
Depends:
R (>= 2.10)
VignetteBuilder: knitr