From a073a3acbaa31adb732a722077f3785495a78ce3 Mon Sep 17 00:00:00 2001
From: Eric Weitz <eric.m.weitz@gmail.com>
Date: Sun, 16 Aug 2020 23:27:22 -0400
Subject: [PATCH] 1.22.0

---
 README.md                   | 4 ++--
 dist/js/ideogram.min.js     | 4 ++--
 dist/js/ideogram.min.js.map | 2 +-
 package-lock.json           | 2 +-
 package.json                | 2 +-
 src/js/version.js           | 2 +-
 6 files changed, 8 insertions(+), 8 deletions(-)
diff --git a/README.md b/README.md
index 232f075c..e032fe81 100644
--- a/README.md
+++ b/README.md
@@ -19,7 +19,7 @@ A [broader overview](https://speakerdeck.com/eweitz/ideogramjs-chromosome-visual
 
 To link directly to the latest release, copy this snippet:
 ```
-<script src="https://cdn.jsdelivr.net/npm/ideogram@1.21.0/dist/js/ideogram.min.js"></script>
+<script src="https://cdn.jsdelivr.net/npm/ideogram@1.22.0/dist/js/ideogram.min.js"></script>
 ```
 
 You can also easily use the library locally:
@@ -44,7 +44,7 @@ import Ideogram from 'ideogram';
 # Usage
 ```html
 <head>
-  <script src="https://cdn.jsdelivr.net/npm/ideogram@1.21.0/dist/js/ideogram.min.js"></script>
+  <script src="https://cdn.jsdelivr.net/npm/ideogram@1.22.0/dist/js/ideogram.min.js"></script>
 </head>
 <body>
 <script>
diff --git a/dist/js/ideogram.min.js b/dist/js/ideogram.min.js
index 085c5f88..6f31d4a1 100644
--- a/dist/js/ideogram.min.js
+++ b/dist/js/ideogram.min.js
@@ -1,3 +1,3 @@
-/*! Ideogram.js, version 1.21.0.  Developed by Eric Weitz.  https://github.com/eweitz/ideogram.  Public domain (CC0 1.0). */
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r=t.organisms[n],o=t.config,i=r.scientificName;Lo.select(t.selector).append("text").attr("class","genomeLabel italic").attr("x",5).attr("y",o.chrLabelSize+(200+3*o.chrWidth)*e).text(i)})}(r)}var $o=function(t){var n,e,r,o,i,a=t.config,s=a.annotationHeight||0;if("vertical"!==a.orientation){t.config.annotLabelHeight=12;var c=t.config.annotLabelHeight;if("demarcateCollinearChromosomes"in t.config==!1&&(t.config.demarcateCollinearChromosomes=!0),n=document.querySelectorAll(".chromosome-set"),r=a.numAnnotTracks*(s+c+4)-a.chrWidth+1,Xo(n,e=function(t,n){var e,r,o,i,a,s,c,l={};for(e=[],r=0;r<t.length;r++)c=n.chromosomesArray[r].id.split("-")[1],o=0===r?r:r-1,i=n.chromosomesArray[o],0===r||c in l==!1?(a=20,l[c]=1):(s=i.width,a=e[o]+s+(n.config.showChromosomeLabels?0:2)+n.config.chrMargin),e.push(a);return e}(n,t),r,t),o=r+2*a.chrWidth+20,a.multiorganism){o*=8;var l=0;e.forEach(t=>{t>l&&(l=t)}),i=l+20}else 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Object?Object.keys(n)[0].length:n.length}return this._config.ploidy||1}_normalize(t){var n,e,r=[];if(!t)return t;for(n in t)"string"==typeof(e=t[n])?("vertical"===this._config.orientation&&(e=e.split("").reverse()),r.push({ancestors:e,existence:this._getexistenceArray(e.length)})):r.push({ancestors:Object.keys(e)[0],existence:e[Object.keys(e)[0]]});return r}_getexistenceArray(t){for(var n=[],e=0;e<t;e++)n.push("11");return n}getSetSize(t){return this._description?this._description[t].ancestors.length:1}getAncestor(t,n){return this._description?this._description[t].ancestors[n]:""}exists(t,n,e){if(this._description){var r=this._description[t].existence[n][e];return Number(r)>0}return!0}}class Jo{constructor(t){this._node=t}getLabel(){return Lo.select(this._node.parentNode).select("text.chrLabel").text()}getSetLabel(){return Lo.select(this._node.parentNode).select("text.chrSetLabel").text()}}var Zo=class{constructor(t,n){if(this._config=t,this._ideo=n,this._ploidy=this._ideo._ploidy,this._translate=void 0,"chrSetMargin"in t)this.chrSetMargin=t.chrSetMargin;else{var e=this._config.chrMargin;this.chrSetMargin=this._config.ploidy>1?e:0}this._tickSize=8,this._isRotated=!1}_getLeftMargin(){return this.margin.left}_getYScale(){return 20/this._config.chrWidth}getChromosomeLabels(t){var n=new Jo(t),e=[];return this._ideo.config.ploidy>1&&e.push(n.getSetLabel()),e.push(n.getLabel()),e.filter((function(t){return t.length>0}))}getChromosomeBandLabelTranslate(t){var n,e,r,o=this._ideo,i=this._tickSize,a=o.config.orientation;return"vertical"===a?r="rotate(-90)translate("+(n=i)+","+(e=o.round(2+t.px.start+t.px.width/2))+")":"horizontal"===a&&(r="translate("+(n=o.round(-i+t.px.start+t.px.width/2))+","+(e=-10)+")"),{x:n,y:e,translate:r}}didRotate(t,n){var e,r,o,i,a,s,c,l,u;r=(e=this._ideo).config.taxid,o=n.id.split("-")[0].replace("chr",""),i=(a=e.chromosomes[r][o]).bands,l=(c=Lo.select(n.parentNode)).attr("transform"),u=/scale\(.*\)/.exec(l),l=l.replace(u,""),c.attr("transform",l),s=a.width,(a=e.getChromosomeModel(i,o,r,t)).oldWidth=s,e.chromosomes[r][o]=a,e.drawChromosome(a),e.handleRotateOnClick(),e.rawAnnots&&(e.displayedTrackIndexes?e.updateDisplayedTracks(e.displayedTrackIndexes):(e.annots=e.processAnnotData(e.rawAnnots),e.drawProcessedAnnots(e.annots),e.config.filterable&&e.initCrossFilter())),!0===e.config.showBandLabels&&(e.drawBandLabels(e.chromosomes),e.hideUnshownBandLabels()),e.onDidRotateCallback&&e.onDidRotateCallback(a)}rotate(t,n,e){var r,o,i,a;r=this._ideo,a=r.selector+" .chrSetLabel, "+r.selector+" .chrLabel",i=document.querySelector(r.selector).getBoundingClientRect(),o=Lo.selectAll(r.selector+" g.chromosome").filter((function(){return this!==e})),this._isRotated?(this._isRotated=!1,r.config.chrHeight=r.config.chrHeightOriginal,r.config.chrWidth=r.config.chrWidthOriginal,r.config.annotationHeight=r.config.annotationHeightOriginal,this.rotateBack(t,n,e,(function(){o.style("display",null),Lo.selectAll(a).style("display",null),r._layout.didRotate(n,e)}))):(this._isRotated=!0,o.style("display","none"),Lo.selectAll(a).style("display","none"),this.rotateForward(t,n,e,(function(){var t,o,a;r.config.chrHeightOriginal=r.config.chrHeight,r.config.chrWidthOriginal=r.config.chrWidth,r.config.annotationHeightOriginal=r.config.annotationHeight;"VerticalLayout"===r._layout._class?(o=i.width-20,a=window.innerWidth-20):(o=i.height-10,a=window.innerHeight-10),t=a<o?a:o,t-=2*r.config.chrMargin,r.config.chrHeight=t,r.config.chrWidth*=2.3,r.config.annotationHeight*=1.7,r._layout.didRotate(n,e)})))}getChromosomeLabelClass(){return 1===this._config.ploidy?"chrLabel":"chrSetLabel"}_getAdditionalOffset(){var t=this._config,n=t.annotationsNumTracks||t.numAnnotTracks||1;return(t.annotationHeight||0)*n}_getChromosomeSetSize(t){return this._ploidy.getSetSize(t)*this._config.chrWidth*2+this.chrSetMargin}getChromosomeSetLabelAnchor(){return"middle"}getChromosomeLabelYPosition(){return-5.5}getChromosomeSetLabelYPosition(t){return 1===this._config.ploidy?this.getChromosomeLabelYPosition(t):-2*this._config.chrWidth}};var Ko=class extends Zo{constructor(t,n){super(t,n),this._class="VerticalLayout",this.margin={top:30,left:15}}rotateForward(t,n,e,r){var o="translate(20, 25) "+this.getChromosomeScale(e);Lo.select(e.parentNode).transition().attr("transform",o).on("end",r);var i=this.getChromosomeLabels(e),a=1.3*(20+this._config.chrWidth);Lo.select(this._ideo.getSvg()).append("g").attr("class","tmp").selectAll("text").data(i).enter().append("text").attr("class",(function(t,n){return 0===n&&2===i.length?"chrSetLabel":null})).attr("x",0).attr("y",a).style("opacity",0).text(String).transition().style("opacity",1),this._ideo.config.orientation="horizontal"}rotateBack(t,n,e,r){var o=this.getChromosomeScaleBack(e),i=this.getChromosomeSetTranslate(t);Lo.select(e.parentNode).transition().attr("transform",i+" "+o).on("end",r),Lo.selectAll(this._ideo.selector+" g.tmp").style("opacity",0).remove(),this._ideo.config.orientation="vertical"}getHeight(){return this._config.chrHeight+1.5*this.margin.top}getWidth(){return"97%"}getChromosomeBandTickY1(){return 2}getChromosomeBandTickY2(){return 10}getChromosomeSetLabelTranslate(){return"rotate(-90)"}getChromosomeBandLabelAnchor(){return null}getChromosomeScale(t){var n,e;return n=Lo.select(this._ideo.selector).node().getBoundingClientRect(),e=t.getBoundingClientRect(),"scale("+n.width/e.height*.97+", "+this._getYScale()+")"}getChromosomeScaleBack(t){var n,e,r;return e=(r=this._ideo.config).taxid,n=t.id.split("-")[0].replace("chr",""),"scale("+this._ideo.chromosomes[e][n].oldWidth/(3*r.chrHeight)*.97+", "+1/this._getYScale()+")"}getChromosomeSetTranslate(t){return"rotate(90) translate("+this.margin.top+", -"+this.getChromosomeSetYTranslate(t)+")"}getChromosomeSetYTranslate(t){var n,e=this._getAdditionalOffset(),r=this._config.chrMargin,o=this._config.chrWidth;if(!this._config.ploidyDesc)return"histogram"===this._config.annotationsLayout?r+t*(r+o+3)+2*this._ideo.config.barWidth:(n=o+t*(r+o)+2*e,e>0?n:n+4+2*t);if(!this._translate){var i;this._translate=[this._ploidy.getSetSize(0)*o*2];for(var a=1;a<this._config.ploidyDesc.length;a++)i=this._translate[a-1],this._translate[a]=i+this._getChromosomeSetSize(a-1)}return this._translate[t]}getChromosomeSetLabelXPosition(){return this._config.chrWidth*this._config.ploidy/-2}getChromosomeLabelXPosition(){return this._config.chrWidth/-2}};var ti=class extends Zo{constructor(t,n){super(t,n),this._class="HorizontalLayout",this.margin={left:20,top:30}}_getLeftMargin(){var t=Zo.prototype._getLeftMargin.call(this);return this._config.ploidy>1&&(t*=1.8),t}rotateForward(t,n,e,r){var o;Lo.select(e.parentNode).transition().attr("transform","rotate(90) translate(30, -37.5) ").on("end",r),o=this.getChromosomeLabels(e),Lo.select(this._ideo.getSvg()).append("g").attr("class","tmp").selectAll("text").data(o).enter().append("text").attr("class",(function(t,n){return 0===n&&2===o.length?"chrSetLabel":null})).attr("x",26).attr("y",(function(t,n){return 12*(n+1+o.length%2)})).style("text-anchor","middle").style("opacity",0).text(String).transition().style("opacity",1),this._ideo.config.orientation="vertical"}rotateBack(t,n,e,r){var o=this.getChromosomeSetTranslate(t);Lo.select(e.parentNode).transition().attr("transform",o).on("end",r),Lo.selectAll(this._ideo.selector+" g.tmp").style("opacity",0).remove(),this._ideo.config.orientation="horizontal"}getHeight(t){void 0===t&&(t=this._config.taxids[0]);var n=this._config.chromosomes[t].length,e=this.getChromosomeSetYTranslate(n-1);return(e+=this._getChromosomeSetSize(n-1))+2*this._getAdditionalOffset()}getWidth(){return this._config.chrHeight+1.5*this.margin.top}getChromosomeSetLabelAnchor(){return"end"}getChromosomeBandLabelAnchor(){return null}getChromosomeBandTickY1(){return 2}getChromosomeBandTickY2(){return 10}getChromosomeSetLabelTranslate(){return null}getChromosomeSetTranslate(t){return"translate("+this._getLeftMargin()+", "+this.getChromosomeSetYTranslate(t)+")"}getChromosomeSetYTranslate(t){if(!this._config.ploidyDesc)return this._config.chrMargin*(t+1);if(!this._translate){this._translate=[1];for(var n=1;n<this._config.ploidyDesc.length;n++)this._translate[n]=this._translate[n-1]+this._getChromosomeSetSize(n-1)}return this._translate[t]}getChromosomeSetLabelXPosition(t){return 1===this._config.ploidy?this.getChromosomeLabelXPosition(t):-20}getChromosomeSetLabelYPosition(t){var n=this._ploidy.getSetSize(t),e=this._config,r=e.chrMargin,o=e.chrWidth;return 1===e.ploidy?o/2+3:n*r/2}getChromosomeLabelXPosition(){return-8}getChromosomeLabelYPosition(){return this._config.chrWidth}};var ni=class extends Zo{constructor(t,n){super(t,n),this._class="PairedLayout",this.margin={left:30}}getHeight(){return this._config.chrHeight+1.5*this.margin.left}getWidth(){return"97%"}getChromosomeBandTickY1(t){return t%2?this._config.chrWidth:2*this._config.chrWidth}getChromosomeBandTickY2(t){var n=this._config.chrWidth;return t%2?n-this._tickSize:2*n+this._tickSize}getChromosomeBandLabelAnchor(t){return t%2?null:"end"}getChromosomeBandLabelTranslate(t,n){var e=n%2?10:-this._config.chrWidth-10,r=this._ideo.round(t.px.start+t.px.width/2)+3;return{x:r,y:r,translate:"rotate(-90) translate("+e+", "+r+")"}}getChromosomeLabelXPosition(){return-this._tickSize}getChromosomeSetLabelXPosition(){return this._config.chrWidth/-2}getChromosomeSetLabelTranslate(){return"rotate(-90)"}getChromosomeSetTranslate(t){var n=this.getChromosomeSetYTranslate(t);return"rotate(90) translate("+this.margin.left+", -"+n+")"}getChromosomeSetYTranslate(t){return 200*(t+1)}};var ei=class extends Zo{constructor(t,n){super(t,n),this._class="SmallLayout",this.margin={left:36.5,top:10};var e=this._ideo.getTaxid(this._ideo.config.organism);this.chrs=t.chromosomes[e];var r=this.chrs.length;this.chrsPerRow=Math.ceil(r/t.rows)}getHeight(){var t=1.25*this._config.chrHeight;return this._config.rows*(t+this.margin.top)}getWidth(){return"97%"}getChromosomeBandLabelTranslate(){}getChromosomeSetLabelTranslate(){return"rotate(-90)"}getChromosomeSetTranslate(t){var n,e;return t>this.chrsPerRow-1?(n=this.margin.left+1.3*this._config.chrHeight,e=this.getChromosomeSetYTranslate(t-this.chrsPerRow)):(n=this.margin.left,e=this.getChromosomeSetYTranslate(t)),"rotate(90) translate("+n+", -"+e+")"}getChromosomeSetYTranslate(t){var n=.3*this._getAdditionalOffset();return this.margin.left*t+this._config.chrWidth+2*n+n*t}getChromosomeSetLabelXPosition(t){return(this._ploidy.getSetSize(t)*this._config.chrWidth+20)/-2+(this._config.ploidy>1?0:this._config.chrWidth)}getChromosomeLabelXPosition(){return this._config.chrWidth/-2}};function ri(t){this.config.annotationsPath&&this.fetchAnnots(this.config.annotationsPath),function(t){if("ploidyDesc"in t.config&&"string"==typeof t.config.ploidyDesc){for(var n=[],e=0;e<t.numChromosomes;e++)n.push(t.config.ploidyDesc);t.config.ploidyDesc=n}t._ploidy=new Qo(t.config)}(this),this._layout=function(t){var n=t.config;return"perspective"in n&&"comparative"===n.perspective?new ni(n,t):"rows"in n&&n.rows>1?new ei(n,t):"vertical"===n.orientation?new Ko(n,t):"horizontal"===n.orientation?new ti(n,t):new Ko(n,t)}(this),function(t){Lo.selectAll(t.config.container+" #_ideogramOuterWrap").remove(),Lo.select(t.config.container).append("div").attr("id","_ideogramOuterWrap").append("div").attr("id","_ideogramTrackLabelContainer").style("position","absolute"),Lo.select(t.config.container+" #_ideogramOuterWrap").append("div").attr("id","_ideogramMiddleWrap").style("position","relative").style("overflow-x","auto").style("transform","translateZ(0)").append("div").attr("id","_ideogramInnerWrap").append("svg").attr("id","_ideogram").attr("class",function(t){var n="";return t.config.showChromosomeLabels&&("horizontal"===t.config.orientation?n+="labeledLeft ":n+="labeled "),!1===t.config.rotatable&&(n+="no-rotate "),t.config.annotationsLayout&&"overlay"===t.config.annotationsLayout&&(n+="faint"),n}(t)).attr("width",t._layout.getWidth()).attr("height",t._layout.getHeight()).html(t.getBandColorGradients())}(this),this.isOnlyIdeogram=1===document.querySelectorAll("#_ideogram").length,function(t){Lo.select(t.config.container+" #_ideogramOuterWrap").append("div").attr("class","_ideogramTooltip").attr("id","_ideogramTooltip").style("opacity",0).style("position","fixed").style("text-align","center").style("padding","4px").style("font","12px sans-serif").style("background","white").style("border","1px solid black").style("border-radius","5px").style("z-index","9000")}(this),this.finishInit(t)}var oi="";function ii(t,n,e){return e.config.dataDir+t[n]}function ai(t,n,e){var r=e.config.ploidy;return"sex"in e.config&&(2===r&&e.sexChromosomes.index+1===n||"female"===e.config.sex&&"Y"===t.name)}function si(t,n,e,r){var o,i,a,s,c;for(o=0;o<n.length;o++)a=n[o],void 0!==t&&(i=t[o]),c=o+r.config.taxids.indexOf(e),s=r.getChromosomeModel(i,a,e,c),"string"!=typeof a&&(a=a.name.split(" ").slice(-1)[0].replace("chr","")),r.chromosomes[e][a]=s,r.chromosomesArray.push(s),ai(s,o,r)||r.drawChromosome(s)}function ci(t,n){"undefined"!=typeof chrBands&&t.length>=chrBands.length/2&&(n.coordinateSystem="bp")}function li(){var t,n,e,r,o=this.config.taxids;for(n=0;n<o.length;n++)t=o[n],e=this.config.chromosomes[t],r=this.bandsArray[t],ci(e,this),this.chromosomes[t]={},this.setSexChromosomes(e),si(r,e,t,this),this.config.showBandLabels&&this.drawBandLabels(this.chromosomes),this.handleRotateOnClick(),this._gotChrModels=!0}function ui(){var t=this;"rotatable"in t.config&&!1===t.config.rotatable?Lo.selectAll(t.selector+" .chromosome").style("cursor","default"):Lo.selectAll(t.selector+" .chromosome").on("click",(function(){t.rotateAndToggleDisplay(this)}))}function hi(){call(this.onLoadCallback)}function fi(t,n,e){var r=e.organisms[t],o=[Wo(r.scientificName)],i=r.assemblies,a=e.config.resolution;n!==i.default&&o.push(n),"9606"===t&&(n in i==="false"&&Object.values(i).includes(config.assembly)||""!==a&&850!==a)&&o.push(a),o=o.join("-");return["9606","10090","10116"].includes(t)&&!e.config.showFullyBanded&&(o+="-no-bands"),o+=".json"}function mi(t,n,e){var r,o,i,a=e.config;return r=e.organisms[t],a.assembly||(e.config.assembly="default"),o=r.assemblies,i=fi(t,e.assemblyIsAccession()?a.assembly:o[a.assembly],e),t in e.organismsWithBands&&(n[t]=i),n}function gi(t,n,e,r){return function(t,n,e){var r=ii(t,n,e);return(!(void 0!==window.chrBands&&""===oi)||oi!==r)&&function(t){return"assembly"in t.config&&!1===/(GCA_)/.test(t.config.assembly)}(e)&&n in t}(n,t,r)?function(t,n,e,r){var o=ii(t,n,r);return r.numBandDataResponses||(r.numBandDataResponses=0),fetch(o).then((function(n){return n.json().then((function(e){oi=o,delete window.chrBands,window.chrBands=e.chrBands,function(t,n,e,r){var o,i,a;for(o in n)a=n[o],t.includes(a)&&""!==a&&(i=o);r.bandData[i]=e}(n.url,t,chrBands,r)}))}))}(n,t,0,r).then((function(){return r.processBandData(t)})):new Promise((function(n){r.processBandData(t),n([t,void 0])}))}var di={},pi={},vi={};function yi(t){var n=(t=t||this).config.container;vi[n]?(pi[n]=!0,di[n]=t):(vi[n]=!0,function(t){return new Promise((function(n){if("number"==typeof t.config.organism){var e=t.config.organism;t.getOrganismFromEutils(e,(function(){t.getTaxids(n)}))}else t.getTaxids(n)}))}(t).then((function(e){var r=e[0];t.config.taxid=r,t.config.taxids=e,function(t,n,e){var r,o,i,a=[];for(i in r={},zo)r[i]="";for(o=0;o<t.length;o++)r=mi(i=String(t[o]),r,e),a.push(gi(i,r,0,e));Promise.all(a).then((function(t){var r,i,a;for(o=0;o<t.length;o++)i=(r=t[o])[0],a=r[1],"bandsArray"in e==!1&&(e.bandsArray={}),e.bandsArray[i]=a;e.writeContainer(n)}))}(e,(new Date).getTime(),t),vi[n]=!1,pi[n]&&(pi[n]=!1,yi(di[n]))})))}class bi{constructor(t,n){this.rawAnnots=this.parseBed(t,n)}static componentToHex(t){var n=parseInt(t,10).toString(16);return 1===n.length?"0"+n:n}static rgbToHex(t,n,e){return"#"+bi.componentToHex(t)+bi.componentToHex(n)+bi.componentToHex(e)}parseGenomicCoordinates(t,n){var e,r,o,i;return e=t[0],r=parseInt(t[1],10),i=(o=parseInt(t[2],10))-r,n&&(e=e.slice(3)),[e,r,o,i]}parseAnnotFromTsvLine(t,n,e){var r,o,i,a,s,c,l,u=t.split(/\s/g);return[i,a,stop,length]=this.parseGenomicCoordinates(u,e),-1===(o=n.indexOf(i))?[null,null]:(r=["",a,length,0],u.length>=4&&(l=u[3],r[0]=l),u.length>=8&&(s=u[8].split(","),c=bi.rgbToHex(s[0],s[1],s[2]),r.push(c)),[o,r])}parseRawAnnots(t,n,e,r){var o,i,a,s,c,l;for(l=!0,!1===isNaN(parseInt(e[n],10))&&(l=!1),o=n;o<e.length;o++)i=e[o],[a,s]=this.parseAnnotFromTsvLine(i,r,l),null!==a&&t[a].annots.push(s);return c=["name","start","length","trackIndex"],e[n].length>=8&&c.push("color"),{keys:c,annots:t}}parseBed(t,n){var e,r,o,i,a=[],s=t.split(/\r\n|\n/);for(r=Object.keys(n.chromosomes[n.config.taxid]),e=0;e<r.length;e++)o=r[e],a.push({chr:o,annots:[]});return i=0,("chr"===s[0].slice(0,3)||isNaN(parseInt(s[0],10)))&&(i=1),this.parseRawAnnots(a,i,s,r)}}var wi=["name","start","length","trackIndex","trackIndexOriginal","color"],_i={3:["00B","DDD","F00"],5:["00D","66D","DDD","F88","F00"],17:["00D","00D","00D","00D","00D","44D","44D","DDD","DDD","DDD","DDD","F88","F66","F22","F22","F00","F00","F00"]};function xi(t){var n,e,r;if(t.rawAnnots.metadata&&t.rawAnnots.metadata.trackLabels)n=t.rawAnnots.metadata.trackLabels;else if(t.config.heatmaps)for(n=[],e=t.config.heatmaps,r=0;r<e.length;r++)n.push(e[r].key);else n=t.rawAnnots.keys.slice(0).filter(t=>!wi.includes(t));return t.displayedTrackIndexes&&(n=n.filter((function(n,e){return t.displayedTrackIndexes.includes(e+1)}))),n}function Ai(t){var n,e,r=t.rawAnnots;if(!r.metadata||r.metadata.heatmapThresholds||t.config.heatmapThresholds)return n=t.config.heatmapThresholds?t.config.heatmapThresholds:t.rawAnnots.metadata.heatmapThresholds,e=_i[n.length+1],(n=n.map((t,n)=>[t,"#"+e[n]])).push(["+","#"+e.slice(-1)[0]]),n}function Ci(t,n,e,r,o){return t===n&&"+"===o&&e>r||e===o||0!==t&&t!==n&&e<=o&&e>r||0===t&&e<=o}function ki(t,n){var e,r,o,i,a,s,c,l;for(e=0;e<t.length;e++)r=t.length-1,i=(o=t[e])[0],a=parseFloat(i),!1===isNaN(a)&&(i=a),0!==e&&(c=parseFloat(t[e-1][0])),s=o[1],Ci(e,r,n,c,i)&&(l=s);return l}function Ti(t){!function(t,n){var e,r,o,i,a=n.config.annotLabelHeight;for(11,i=n.config.demarcateCollinearChromosomes?2:0,(o=Lo.select(n.config.container+" #_ideogramTrackLabelContainer")).html(""),r=n.config.annotationHeight+a+4,e=0;e<t.length;e++)o.style("position","absolute").append("div").attr("class","_ideogramTrackLabel").style("opacity",1).style("position","absolute").style("text-align","center").style("padding","1px").style("font","11px sans-serif").style("background","white").style("line-height","10px").style("z-index","5").style("left",11+i+"px").style("top",r*e+i+"px").style("width","max-content").style("transform-origin","bottom left").style("text-align","left").html(t[e])}(xi(t),t)}function Si(t,n,e){var r,o,i,a,s,c=t.width,l=[],u=e.config.annotLabelHeight,h=e.config.numAnnotTracks;for(r=0;r<h;r++)i=e.config.annotationHeight+u+4,s=t.id+"-canvas-"+r,o=n,t.chrIndex>0&&(o+=e.config.chrMargin*t.chrIndex-1),a=Lo.select(e.config.container+" #_ideogramInnerWrap").append("canvas").attr("id",s).attr("width",c+1).attr("height",i).style("position","absolute").style("left",o+"px").style("top",i*r+1+"px").nodes()[0].getContext("2d"),l.push([a,t]);return l}function Mi(t,n,e){var r,o,i,a,s=e.config.annotLabelHeight,c=e.config.annotationHeight,l=e.config.demarcateCollinearChromosomes,u=c+s+4;for(r=0;r<t.length;r++)if(i=n[(o=t[r]).trackIndex][0],a=n[o.trackIndex][1],i.fillStyle=o.color,l){if(o.startPx<1||o.startPx>a.width-1)continue;i.fillRect(o.startPx,1,.5,u)}else i.fillRect(o.startPx,s+1,.5,c);if(l)for(r=0;r<n.length;r++)i=n[r][0],a=n[r][1],i.fillStyle="#555",0===a.chrIndex&&i.fillRect(0,0,1,u),i.fillRect(a.width-1,0,1.1,u),i.fillRect(0,0,a.width+1,1),e.config.chrMargin&&i.fillRect(0,0,1.1,u)}function Li(t,n,e){var r,o,i,a=e.config.annotationHeight,s=e._layout.margin.top;for(i=t.values,r=0;r<i.length;r++)n.fillStyle=i[r],o=(r-1)*a,n.fillRect(o,t.startPx+s,a,2)}function Ni(t,n){var e,r,o=n.config.container,i=n._layout.margin.top,a=n.config.chrHeight+i,s=n.config.annotationHeight*t[0].values.length;for(Lo.selectAll(o+" canvas").remove(),Lo.select(o+" #_ideogramInnerWrap").style("max-width",s+"px"),Lo.select(o+" 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r,o,i;for(r=0;r<e.rows.length;r++)t+="<li>"+(i=e.rows[r]).name+"</li>",o=19*r,"name"in e&&(o+=19),n+='<g transform="translate(0, '+o+')">'+Xi(i)+"</g>";return[t,n]}function Ui(t){var n,e,r=[],o=this.chromosomes[this.config.taxid];if("annots"in t[0]||"values"in t[0])return this.drawProcessedAnnots(t);for(e in o)r.push({chr:e,annots:[]});r=function(t,n){var e,r,o,i;for(e=0;e<t.length;e++)for(o=t[e],r=0;r<n.length;r++)if(o.chr===n[r].chr){i=[o.name,o.start,o.stop-o.start],"color"in o&&i.push(o.color),"shape"in o&&i.push(o.shape),n[r].annots.push(i);break}return n}(t,r),n=function(t){var n=["name","start","length"];return"color"in t[0]&&n.push("color"),"shape"in t[0]&&n.push("shape"),n}(t),this.rawAnnots={keys:n,annots:r},this.annots=this.processAnnotData(this.rawAnnots),this.drawProcessedAnnots(this.annots)}function Vi(t,n,e){var r;!function(t,n){var e,r;if(!/heatmap/.test(t)&&"histogram"!==t){for(r=0,e=0;e<n.length;e++)r+=n[e].annots.length;r>2e3&&console.warn('Rendering more than 2000 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na(t,n,e,r,o){t.append("line").attr("class","syntenyBorder").attr("x1",n).attr("x2",e).attr("y1",r.startPx).attr("y2",o.startPx),t.append("line").attr("class","syntenyBorder").attr("x1",n).attr("x2",e).attr("y1",r.stopPx).attr("y2",o.stopPx)}function ea(t,n){var e=(new Date).getTime();(function(t,n,e){var r,o,i,a,s,c,l,u;for(r=0;r<t.length;r++)o=t[r],[i,a]=ta(o,e),Zi(s=Ji(n,i.chr.id+"_"+i.start+"_"+i.stop+"___"+a.chr.id+"_"+a.start+"_"+a.stop,e),l=(c=e.config.chrWidth)+46,u=c+240,i,a,o),na(s,l,u,i,a)})(t,Lo.select(n.selector).insert("g",":first-child").attr("class","synteny"),n),function(t,n){var e=(new Date).getTime();n.config.debug&&console.log("Time in drawSyntenicRegions: "+(e-t)+" ms")}(e,n)}function ra(t,n,e,r,o){t.append("line").attr("class","syntenyBorder").attr("x1",r.startPx-15).attr("x2",o.startPx-15).attr("y1",n).attr("y2",e),t.append("line").attr("class","syntenyBorder").attr("x1",r.stopPx-15).attr("x2",o.stopPx-15).attr("y1",n).attr("y2",e)}function oa(t,n){var e=(new 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r){t.append("text").attr("id",a[0]).attr("y",r.startPx+3).text(r.name);var s=document.querySelector("#"+a[0]).getBoundingClientRect().width;Lo.select("#"+a[0]).attr("x",n-15-s)}"name"in o&&t.append("text").attr("id",a[1]).text(o.name).attr("x",e+15).attr("y",o.startPx+3).text(o.name)}function sa(t){var n=(new Date).getTime(),e=this.config;if(e.multiorganism&&"collinear"===e.geometry)return"vertical"===e.orientation?ea(t,this):oa(t,this);(function(t,n,e,r){var o,i,a,s,c,l,u,h,f;for(o=0;o<t.length;o++)i=t[o],[a,s]=ta(i,r,e),l=Ji(n,c=a.chr.id+"_"+a.start+"_"+a.stop+"___"+s.chr.id+"_"+s.start+"_"+s.stop,r),u=r.config.chrWidth,Zi(l,h=r._layout.getChromosomeSetYTranslate(0),f=r._layout.getChromosomeSetYTranslate(1)-u,a,s,i),ia(l,h,f,a,s,i),aa(l,h,f,a,s,c)})(t,Lo.select(this.selector).insert("g",":first-child").attr("class","synteny"),this._layout.margin.left,this),function(t,n){var e=(new Date).getTime();n.config.debug&&console.log("Time in drawSyntenicRegions: "+(e-t)+" ms")}(n,this)}function ca(){this.config.numAnnotTracks=this.config.annotationsNumTracks,Lo.selectAll(this.selector+" .annot").remove(),this.drawAnnots(this.processAnnotData(this.rawAnnots))}function la(t){var n,e,r,o=this.rawAnnots.annots;return this.config.numAnnotTracks=t.length,n=function(t,n){var e,r,o,i,a,s,c;for(r=[],i=0;i<t.length;i++){for(o=t[i],a=[],s=0;s<o.annots.length;s++)c=(e=o.annots[s].slice())[3]+1,n.includes(c)&&(e[3]=n.indexOf(c),a.push(e));r.push({chr:o.chr,annots:a})}return r}(o,t),r={keys:this.rawAnnots.keys,annots:n},"collinear"===this.config.geometry&&$o(this),e=this.processAnnotData(r),Lo.selectAll(this.selector+" .annot").remove(),this.displayedTrackIndexes=t,this.drawAnnots(e),e}function ua(t){var n,e;return(n=t.keys).length<4||"trackIndex"!==n[3]||"trackIndexOriginal"===n[4]||(e=function(t,n){var e,r,o,i,a,s,c,l=[];for(c=1,e=0;e<t.length;e++){for(o=t[e],a=[],r=0;r<o.annots.length;r++)(s=(i=o.annots[r].slice())[3])+1>c&&(c=s+1),i.splice(4,0,s),a.push(i);l.push({chr:o.chr,annots:a})}return n.numAvailTracks=c,l}(t.annots,this),n.splice(4,0,"trackIndexOriginal"),t={keys:n,annots:e},this.rawAnnots.metadata&&(t.metadata=this.rawAnnots.metadata)),t}var ha=[["F00"],["F00","88F"],["F00","CCC","88F"],["F00","FA0","0AF","88F"],["F00","FA0","CCC","0AF","88F"],["F00","FA0","875","578","0AF","88F"],["F00","FA0","875","CCC","578","0AF","88F"],["F00","FA0","7A0","875","0A7","578","0AF","88F"],["F00","FA0","7A0","875","CCC","0A7","578","0AF","88F"],["F00","FA0","7A0","875","552","255","0A7","578","0AF","88F"]];function fa(t,n,e,r,o,i,a){return a.config.annotationTracks?o=function(t,n,e,r,o){var i;return n.trackIndex=e[3],(i=o.config.annotationTracks[n.trackIndex]).color&&(n.color=i.color),i.shape&&(n.shape=i.shape),t[r].annots.push(n),t}(o,t,e,i,a):"trackIndex"===n[3]&&1!==a.numAvailTracks?[o,r]=function(t,n,e,r,o,i){var a=ha[i.numAvailTracks-1];return t.trackIndex=n[3],t.trackIndexOriginal=n[4],t.color="#"+a[t.trackIndexOriginal],t.trackIndex>i.config.numTracks-1?(t.trackIndex in e?e[t.trackIndex].push(t):e[t.trackIndex]=[t],[r,e]):(r[o].annots.push(t),[r,e])}(t,e,r,o,i,a):o=function(t,n,e,r){return n.trackIndex=0,n.color||(n.color=r.config.annotationsColor),n.shape||(n.shape="triangle"),t[e].annots.push(n),t}(o,t,i,a),[o,r]}function ma(t,n,e,r,o,i,a){var s,c,l,u;for(s=0;s<e.annots.length;s++){for(u=e.annots[s],l={},c=0;c<i.length;c++)l[i[c]]=u[c];l.stop=l.start+l.length,l.chr=e.chr,l.chrIndex=o,l.startPx=a.convertBpToPx(r,l.start),l.stopPx=a.convertBpToPx(r,l.stop),l.px=Math.round((l.startPx+l.stopPx)/2),[t,n]=fa(l,i,u,n,t,o,a)}return[t,n]}function ga(t){console.warn('Chromosome "'+t.chr+'" undefined in ideogram; '+t.annots.length+" annotations not shown")}function da(t){var n,e,r;return n=t.keys,t=t.annots,[e,r]=function(t,n,e){var r,o,i,a,s=[],c={};for(r=-1,o=0;o<t.length;o++)i=t[o],void 0!==(a=e.chromosomes[e.config.taxid][i.chr])?(r++,s.push({chr:i.chr,annots:[]}),"heatmap-2d"!==e.config.annotationsLayout?[s,c]=ma(s,c,i,a,r,n,e):[s,c]=Pi(s,c,i,a,r,n,e)):ga(i);return[s,c]}(t,n,this),e=function(t,n){var e,r,o,i,a,s;for(e=t,t=[],s=n.chromosomesArray,r=0;r<s.length;r++)for(a=s[r].name,o=0;o<e.length;o++)(i=e[o]).chr===a&&t.push(i);return t}(e,this),function(t,n){var e,r=n.config.annotationsLayout,o=n.config.numAnnotTracks;!/heatmap/.test(r)&&o>10&&console.error("Ideogram only displays up to 10 tracks at a time.  You specified "+o+" tracks.  Perhaps consider a different way to visualize your data."),(e=Object.keys(t).length)&&console.warn("Ideogram configuration specified "+o+" tracks, but loaded annotations contain "+e+" extra tracks.")}(r,this),e}class pa{constructor(t,n){this.matrix=t,this.ideo=n}setRawAnnots(){var t,n,e;return t=this,n=this.ideo,e=this.matrix,new Promise((function(r){t.rawAnnots=t.fetchCoordinates(n).then((function(o){t.coordinates=o,r(t.parseExpressionMatrix(e,n))}))}))}fetchCoordinates(t){var n={};if("human"===t.config.organism){var e=t.config.dataDir+"../../annotations/Homo_sapiens,_Ensembl_80.tsv";return new Promise((function(r){t.fetch(e,"text").then((function(t){var e,o,i,a,s,c,l,u;for(e=t.split(/\r\n|\n/).slice(1),o=0;o<e.length;o++)[i,a,s,u,c]=e[o].split(/\s/g),i=parseInt(i),l=(a=parseInt(a))-i,n[s]=[c,i,l];r(n)}))}))}throw Error("Expression matrix parsing is only supported for human")}parseAnnotFromTsvLine(t,n){var e,r,o,i,a,s=t.split(/\s/g);return(i=s[0])in this.coordinates==!1?[null,null]:(a=s.slice(1).map(t=>parseFloat(t)),[r,o,length]=this.coordinates[i],-1===(e=n.indexOf(r))?[null,null]:[e,[i,o,length].concat(a)])}parseExpressionMatrix(t,n){var e,r,o,i,a,s,c=[],l=t.split(/\r\n|\n/);for(r=Object.keys(n.chromosomes[n.config.taxid]),e=0;e<r.length;e++)c.push({chr:r[e],annots:[]});for(e=1;e<l.length;e++)i=l[e],[a,s]=this.parseAnnotFromTsvLine(i,r),null!==a&&c[a].annots.push(s);return o=l[0].split(/\s/g),{keys:["name","start","length"].concat(o),annots:c}}}function va(){var t=this.config;!function(t){var n,e=t.config;e.annotationHeight||("heatmap"===e.annotationsLayout?n=e.chrWidth-1:(n=Math.round(e.chrHeight/100))<3&&(n=3),t.config.annotationHeight=n)}(this),t.annotationsPath||t.localAnnotationsPath||this.annots||t.annotations?function(t,n){n.annotationTracks?t.config.numAnnotTracks=n.annotationTracks.length:n.annotationsNumTracks?t.config.numAnnotTracks=n.annotationsNumTracks:t.config.numAnnotTracks=1,t.config.annotTracksHeight=n.annotationHeight*n.numAnnotTracks,void 0===n.barWidth&&(t.config.barWidth=3)}(this,t):(this.config.annotTracksHeight=0,this.config.numAnnotTracks=0),void 0===t.annotationsColor&&(this.config.annotationsColor="#F00"),t.onClickAnnot&&(this.onClickAnnotCallback=t.onClickAnnot),function(t,n){!1!==n.showAnnotTooltip&&(t.config.showAnnotTooltip=!0),n.onWillShowAnnotTooltip&&(t.onWillShowAnnotTooltipCallback=n.onWillShowAnnotTooltip)}(this,t)}function ya(){var t=this.config;this.rawAnnots.annots=this.rawAnnots.annots.sort((function(t,n){return t.chr.localeCompare(n.chr,"en",{numeric:!0})})),this.onLoadAnnotsCallback&&this.onLoadAnnotsCallback(),("heatmapThresholds"in t||"metadata"in this.rawAnnots&&"heatmapThresholds"in this.rawAnnots.metadata)&&("heatmap"===t.annotationsLayout?function(t){var n,e,r,o,i,a,s=t.config.heatmapThresholds;for(r=[],e=(i=t.rawAnnots).keys.slice(3),o=[],a=[],!i.metadata&&isNaN(s[0])||(s=Ai(t)),n=0;n<e.length;n++)r.push({key:e[n],thresholds:s}),o.push({id:e[n]}),a.push(n+1);t.config.annotationsNumTracks=e.length,t.config.annotationsDisplayedTracks=a,t.config.heatmaps=r,t.config.annotationTracks=o}(this):"heatmap-2d"===t.annotationsLayout&&(this.config.heatmapThresholds=Ai(this))),t.heatmaps&&this.deserializeAnnotsForHeatmap(this.rawAnnots)}function ba(t){var n,e,r=this,o=r.config;e="heatmap-2d"===o.annotationsLayout,"http"===t.slice(0,4)||e?(n=e?"":function(t){var n,e;return"bed"!==(e=(n=t.split("?")[0].split("."))[n.length-1])&&"json"!==e?(e=e.toUpperCase(),void alert("Ideogram.js only supports BED and Ideogram JSON at the moment.  Sorry, check back soon for "+e+" support!")):e}(t),r.fetch(t,"text").then((function(t){(r.rawAnnotsResponse=t,e)?new pa(t,r).setRawAnnots().then((function(t){r.rawAnnots=t,r.afterRawAnnots()})):(r.rawAnnots="bed"===n?new bi(t,r).rawAnnots:JSON.parse(t),r.afterRawAnnots())}))):r.fetch(t).then((function(t){r.rawAnnotsResponse=t,r.rawAnnots=t,r.afterRawAnnots()}))}function wa(t){var n,e,r,o,i,a,s;for(n=[],e=[],r=this.chromosomesArray,o=0;o<r.length;o++)i=r[o].name,e.push(i),n.push({chr:i,annots:[]});for(o=0;o<t.length;o++)a=t[o],-1!==(s=e.indexOf(a.chr))&&(n[s]=a);return n}function _a(t,n){var e,r;return e=n.esearch+"&db=taxonomy&term="+t,Lo.json(e).then((function(n){return r=n.esearchresult.idlist[0],[t,r]}))}function xa(t,n){var e,r,o=this;t=o.config.organism,r=o.esummary+"&db=taxonomy&id="+t,Lo.json(r).then((function(r){return e=r.result[String(t)].commonname,o.config.organism=e,n(e)}))}function Aa(t,n,e){var r,o,i,a,s,c=e.config;(function(t,n){var e,r,o;if(n.assemblyIsAccession())return new Promise((function(e){n.coordinateSystem="bp",n.getAssemblyAndChromosomesFromEutils(t,e)}));e=n.config.dataDir,r=Wo(n.organisms[t].scientificName),o=[t],["9606","10090","10116"].includes(t)&&!n.config.showFullyBanded&&(r+="-no-bands");var i=e+r+".json";return new Promise((function(t,n){fetch(i).then((function(e){if(!1!==e.ok)return e.json().then((function(n){t(n.chrBands)}));n(Error("Fetch failed for "+i))}))})).then((function(e){var r,i,a,s,c=[""],l=[],u={};n.bandData[t]=e;for(var h=0;h<e.length;h++)r=(a=e[h].split(" "))[0],s=a.slice(-1)[0],r in u||(l.push({name:r,type:"nuclear",length:s}),u[r]=1);return l=l.sort(Ideogram.sortChromosomes),i={bp:0,iscn:0},l.forEach(t=>{t.length>i.bp&&(i.bp=t.length)}),n.maxLength[t]=i,c.push(l),c.push(o),c}),(function(){return new Promise((function(e){n.coordinateSystem="bp",n.getAssemblyAndChromosomesFromEutils(t,e)}))}))})(t,e).then((function(l){r=l[0],o=l[1],"chromosomes"in c==!1||null===c.chromosomes?(e.config.chromosomes={},e.config.chromosomes[t]=o):(c.multiorganism?t in c.chromosomes?i=c.chromosomes[t]:(a=Wo(e.getScientificName(t)),e.config.chromosomes[t]=c.chromosomes[a].slice(),i=e.config.chromosomes[t]):i=c.chromosomes,s=o.filter(t=>i.includes(t.name)),e.config.chromosomes[t]=s),e.chromosomes[t]=e.config.chromosomes[t].slice(),e.organisms[t].assemblies={default:r},n()}))}function Ca(t,n){var e,r;for(e in n.organisms)if(r=n.organisms[e],e===Wo(t)||Wo(r.commonName)===Wo(t)||Wo(r.scientificName)===Wo(t))return!0;return!1}function ka(t){var n,e,r,o,i,a=t.config;return n=[],e={},function(t,n){var e,r,o,i=[],a={};for(o=0;o<t.length;o++)r=!1===Ca(e=t[o],n)?_a(e,n).then((function(t){var e,r,o=t[1];r=(e=t[0].replace("-"," "))[0].toUpperCase()+e.slice(1),a[o]={scientificName:r,commonName:"",assemblies:{default:""}},Object.assign(n.organisms,a)})):new Promise((function(t){var r=n.getTaxid(e);a[r]=n.organisms[r],t()})),i.push(r);return Promise.all(i).then((function(){return a}))}(a.multiorganism?a.organism:[a.organism],t).then((function(t){var s=t[o];for(o in t)s=t[o],n.push(o),a.multiorganism&&(void 0!==a.chromosomes?((i=Object.keys(a.chromosomes).map(t=>Wo(t))).includes(Wo(s.scientificName))?r=s.scientificName:i.includes(Wo(s.commonName))&&(r=s.commonName),Wo(r)in a.chromosomes?e[o]=a.chromosomes[Wo(r)]:e[o]=a.chromosomes[r.toLowerCase()]):e=null);return[e,n]}))}function Ta(t,n){ka(n).then((function([e,r]){var o,i,a,s,c,l=n.config,u=[];for(o=0;o<r.length;o++)i=r[o],s=n.organisms[i].assemblies,c=Object.values(s),""===s.default||n.assemblyIsAccession()&&!c.includes(l.assembly)?a=new Promise((function(t){Aa(i,t,n)})):(n.config.taxids=r,n.config.multiorganism&&(n.config.chromosomes=e),a=new Promise((function(t){t()}))),u.push(a);Promise.all(u).then((function(){return r=function(t){var n,e,r;if(n=t.config.organism,e=[],Array.isArray(n))for(r=0;r<n.length;r++)e.push(t.getTaxid(n[r]));else e.push(t.getTaxid(n));return e}(n),n.config.taxids=r,t(r)}))}))}function Sa(t){var n;n="taxid"in this.config,this.config.multiorganism=function(t,n){return"organism"in n.config&&n.config.organism instanceof Array||t&&n.config.taxid instanceof Array}(n,this),this.config.multiorganism&&(this.coordinateSystem="bp"),"organism"in this.config?Ta(t,this):function(t,n,e){var r;e.config.multiorganism?t&&(r=e.config.taxid):(t&&(r=[e.config.taxid]),e.config.taxids=r),n(r)}(n,t,this)}function Ma(t,n){var e,r;return[e,r]=function(t,n){var e=t.genome;return"mitochondrion"===e?function(t,n){var e,r;return n.config.showNonNuclearChromosomes?(e=t.genome,[-1===(r=t.subtype.split("|").indexOf("plasmid"))?"MT":t.subname.split("|")[r],e]):[null,null]}(t,n):"chloroplast"===e||"plastid"===e?function(t){return t.config.showNonNuclearChromosomes?["CP","chloroplast"]:[null,null]}(n):"apicoplast"===e?function(t){return t.config.showNonNuclearChromosomes?["AP","apicoplast"]:[null,null]}(n):function(t){var n,e;return"nuclear",n=t.subtype.split("|").indexOf("chromosome"),void 0!==(e=t.subname.split("|")[n])&&"chr"===e.substr(0,3)&&(e=e.substr(3)),[e,"nuclear"]}(t)}(t,n),{name:e,length:t.slen,type:r}}function La(t,n){var e,r=this,o=function(t,n){var e;return e=n.assemblyIsAccession()?n.config.assembly+"%22[Assembly%20Accession]":t+"%22[taxid]AND%20(%22latest%20refseq%22[filter])%20",n.esearch+"&db=assembly&term=%22"+e+"AND%20(%22chromosome%20level%22[filter]%20OR%20%22complete%20genome%22[filter])"}(t,r);Lo.json(o).then((function(t){return function(t,n){var e,r;return e=t.esearchresult.idlist[0],r=n.esummary+"&db=assembly&id="+e,Lo.json(r)}(t,r)})).then((function(t){var n=t.result.uids[0];return e=t.result[n],function(t,n){var e;return e="&db=nuccore&dbfrom=assembly&linkname=assembly_nuccore&cmd=neighbor_history&from_uid="+t,Lo.json(n.elink+e).then((function(t){var r=t.linksets[0].webenv;return e="&db=nuccore&term=%231+AND+%28sequence_from_chromosome[Properties]+OR+sequence_from_plastid[Properties]+OR+sequence_from_mitochondrion[Properties]%29&WebEnv="+r+"&usehistory=y&retmax=1000",n.esearch+e}))}(n,r)})).then((function(t){return Lo.json(t)})).then((function(t){return function(t,n){var e,r;return e=t.esearchresult.idlist.join(","),r=n.esummary+"&db=nucleotide&id="+e,Lo.json(r)}(t,r)})).then((function(o){var i=function(t,n,e){var r,o,i,a,s={},c=[];for(r in t)"uids"!==r&&(i=(o=Ma(t[r],e)).name+"_"+o.length,null!==o.type&&i in s==!1&&c.push(o),s[i]=1);return c=c.sort(Ideogram.sortChromosomes),a={bp:0,iscn:0},c.forEach(t=>{t.length>a.bp&&(a.bp=t.length)}),a.bp>e.maxLength.bp&&(e.maxLength.bp=a.bp),e.maxLength[n]=a,e.coordinateSystem="bp",c}(o.result,t,r);return n([e,i])}),(function(t){console.warn(t)}))}function Na(){var t=this.bandsToShow.join(",");Lo.selectAll(this.selector+" .bandLabel, .bandLabelStalk").style("display","none"),Lo.selectAll(t).style("display","")}function 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o,i,a,s,c,l=0,u=n.id.split("-")[1],h=r.coordinateSystem,f=r.config.chrHeight;for(o=0;o<t.length;o++)a=(i=t[o])[h].stop-i[h].start,r._layout._isRotated?s=f*a/n.length:(c="relative"===r.config.chromosomeScale?r.maxLength[u][h]:r.maxLength[h],s=f*n.length/c*a/n.length),t[o].px={start:l,stop:l+s,width:s},l=t[o].px.stop,e&&"acen"===i.stain&&"p"===i.name[0]&&(n.pcenIndex=o);return[t,n,l]}(n,t,o,this):(i="relative"===this.config.chromosomeScale?this.maxLength[a][this.coordinateSystem]:this.maxLength[this.coordinateSystem],r=e*t.length/i),t.width=r,t.scale=function(t,n,e){var r=e.config.chrHeight,o=t.length,i=e.maxLength,a=t.id.split("-")[1],s={};return s.bp=r/i.bp,!0===e.config.multiorganism?"relative"===e.config.chromosomeScale?(s.iscn=r*o/i[a].bp,s.bp=r/i[a].bp):s.iscn=r*o/i.bp:n&&(s.iscn=r/i.iscn),s}(t,o,this),t.bands=n,t}function Ys(t,n,e,r){var o,i,a={};return o=void 0!==t,(a=function(t,n,e,r){return void 0!==n?(t.name=e,t.length=n[n.length-1][r.coordinateSystem].stop,t.type="nuclear"):t=e,t}(a,t,n,this)).chrIndex=r,a.id="chr"+a.name+"-"+e,!0===this.config.fullChromosomeLabels&&(i=this.organisms[e],a.name=i.scientificName+" chr"+a.name),a.bands=t,(a=this.getChromosomePixels(a)).centromerePosition=function(t,n){const e=t&&"p"===n[0].name[0]&&"q"===n[1].name[0]&&n[0].bp.stop-n[0].bp.start<2e6;let r=!1;if(t){const e=n.slice(-1)[0],o=n.slice(-2)[0];r=t&&"p"===o.name[0]&&"q"===e.name[0]&&e.bp.stop-e.bp.start<2e6}return e?"telocentric-p":r?"telocentric-q":""}(o,t),a=function(t,n){return n&&1===t.bands.length&&delete t.bands,t}(a,o)}class Gs{constructor(t){this._model=t,this._class="ModelAdapter"}static getInstance(t){return t.bands?new Gs(t):new Xs(t)}getModel(){return this._model}getCssClass(){return""}}class Xs extends Gs{constructor(t){super(t),this._class="ModelNoBandsAdapter"}getModel(){return this._model.bands=[],this._model.width>1&&this._model.bands.push({name:"q",px:{start:0,stop:this._model.width,width:this._model.width},bp:{start:1,stop:this._model.length}}),this._model}getCssClass(){return"noBands"}}class $s{constructor(t){this._config=t,this._ploidy=new Qo(this._config)}getArmColor(t,n,e){return this._config.armColors?this._config.armColors[e]:this._config.ancestors?this._getPolyploidArmColor(t,n,e):null}getBorderColor(t,n,e){return n<this._config.ploidy||this._ploidy.exists(t,n,e)?"#000":"#fff"}_getPolyploidArmColor(t,n,e){if(this._ploidy.exists(t,n,e)){var r=this._ploidy.getAncestor(t,n,e);return this._config.ancestors[r]}return"transparent"}}class Us{constructor(t){this._data=t,this.start=t.start,this.stop=t.stop,this.length=this.stop-this.start}getColor(t){return"ploidy"in this._data?"ploidy"in this._data&&this._data.ploidy[t]?this._getColor(t):"transparent":this._getColor(t)}_getColor(t){return Array.isArray(this._data.color)?this._data.color[t]:this._data.color}}class Vs{constructor(t,n,e){this._adapter=t,this._model=this._adapter.getModel(),this._config=n,this._ideo=e,this._color=new $s(this._config),this._bumpCoefficient=5}static getInstance(t,n,e){const r=t.getModel().centromerePosition;return"telocentric-p"===r?new Js(t,n,e):"telocentric-q"===r?new Zs(t,n,e):new Qs(t,n,e)}_addPArmShape(t,n){return n?t.concat(this._getPArmShape()):t}_addQArmShape(t,n){return n?t.concat(this._getQArmShape()):t}render(t,n,e){var r,o,i,a,s,c,l;return r=this,t=t.append("g").attr("class","bands").attr("clip-path","url(#"+this._model.id+"-chromosome-set-clippath)"),o=this._renderArm(t,n,e,"p"),i=this._renderArm(t,n,e,"q"),this._renderRangeSet(t,n,e),a=[],a=this._addPArmShape(a,o),a=this._addQArmShape(a,i),s="0",c="",l=this.isFullyBanded(),"ancestors"in this._ideo.config&&!("rangeSet"in this._ideo.config)?(c=r._color.getArmColor(n,e,0),l&&(s="0.5")):l?(s=null,c="transparent"):"ancestors"in this._ideo.config||(s="1"),t.append("g").attr("class","chromosome-border").selectAll("path").data(a).enter().append("path").attr("fill",c).style("fill-opacity",s).attr("stroke",(function(t,o){return r._color.getBorderColor(n,e,o)})).attr("stroke-width",(function(t){return"strokeWidth"in t?t.strokeWidth:1})).attr("d",(function(t){return t.path})).attr("class",(function(t){return t.class})),a}_renderRangeSet(t,n,e){var r,o,i,a;"rangeSet"in this._config&&(o=this._config.rangeSet.filter((function(t){return t.chr-1===n})).map((function(t){return new Us(t)})),i=t.append("g").attr("class","range-set"),a=(r=this)._ideo,i.selectAll("rect.range").data(o).enter().append("rect").attr("class","range").attr("x",(function(t){return a.convertBpToPx(r._model,t.start)})).attr("y",0).attr("width",(function(t){return a.convertBpToPx(r._model,t.length)})).attr("height",this._config.chrWidth).style("fill",(function(t){return t.getColor(e)})))}_getShapeData(){var t,n,e,r;for(n=0;n<this._model.bands.length;n++)if("q"===this._model.bands[n].name[0]){t=this._model.bands[n];break}return e=this._model.bands.length-1,r=this._model.bands[e].px.stop,{x1:0,x2:t?t.px.start:r,x3:r,w:this._config.chrWidth,b:this._config.chrWidth/this._bumpCoefficient}}_getPArmShape(){var t=this._getShapeData(),n=t.x2-t.b;return this.isFullyBanded()||"ancestors"in this._ideo.config?{class:"",path:"M"+t.b+",0 L"+n+",0 Q"+(t.x2+t.b)+","+t.w/2+","+n+","+t.w+" L"+t.b+","+t.w+" Q-"+t.b+","+t.w/2+","+t.b+",0"}:[{class:"",path:"M"+t.b+",0 L"+(n-2)+",0 L"+(n-2)+","+t.w+" L"+t.b+","+t.w+" Q-"+t.b+","+t.w/2+","+t.b+",0"},{class:"acen",path:"M"+n+",0 Q"+(t.x2+t.b)+","+t.w/2+","+n+","+t.w+" L"+n+","+t.w+" L"+(n-2)+","+t.w+" L"+(n-2)+",0"}]}_getQArmShape(){var t=this._getShapeData(),n=t.x3-t.b,e=t.x2+t.b;return this.isFullyBanded()||"ancestors"in this._ideo.config?{class:"",path:"M"+e+",0 L"+n+",0 Q"+(t.x3+t.b)+","+t.w/2+","+n+","+t.w+" L"+e+","+t.w+" Q"+(t.x2-t.b)+","+t.w/2+","+e+",0"}:[{path:"M"+e+",0 L"+n+",0 Q"+(t.x3+t.b)+","+t.w/2+","+n+","+t.w+" L"+e+","+t.w+" L"+e+",0"},{class:"acen",path:"M"+e+",0Q"+(t.x2-t.b)+","+t.w/2+","+e+","+t.w+" L"+e+","+t.w+"L"+(e+2)+","+t.w+"L"+(e+2)+",0"}]}isFullyBanded(){return this._model.bands&&(2!==this._model.bands.length||"q"===this._model.bands[0].name[0])}_renderBands(t,n,e,r,o){var i,a,s;a="p"===o?0:1,s="","ancestors"in(i=this)._ideo.config&&!i.isFullyBanded()&&(s=i._color.getArmColor(n,e,a)),t.selectAll("path.band."+o).data(r).enter().append("path").attr("id",(function(t){return i._model.id+"-"+t.name.replace(".","-")})).attr("class",(function(t){return"band "+o+"-band "+t.stain})).attr("d",(function(t){var n;return"M "+i._ideo.round(t.px.start)+", 0l "+(n=i._ideo.round(t.px.width))+" 0 l 0 "+i._config.chrWidth+" l -"+n+" 0 z"})).style("fill",s)}_renderArm(t,n,e,r){var o=this._model.bands.filter((function(t){return t.name[0]===r}));return this._renderBands(t,n,e,o,r),Boolean(o.length)}}class Qs extends Vs{constructor(t,n,e){super(t,n,e),this._class="MetacentricChromosome"}}class Js extends Vs{constructor(t,n,e){super(t,n,e),this._class="TelocentricPChromosome",this._pArmOffset=3}_addPArmShape(t){return t.concat(this._getPArmShape())}_getPArmShape(){var t=this._getShapeData();return t.o=this._pArmOffset,[{class:"acen",path:"M"+(t.x2+2)+",1L"+(t.x2+t.o+3.25)+",1 L"+(t.x2+t.o+3.25)+","+(t.w-1)+" L"+(t.x2+2)+","+(t.w-1)},{class:"gpos66",path:"M"+(t.x2-t.o+5)+",0L"+(t.x2-t.o+3)+",0 L"+(t.x2-t.o+3)+","+t.w+" L"+(t.x2-t.o+5)+","+t.w,strokeWidth:.5}]}_getQArmShape(){var t=this._getShapeData(),n=t.x3-t.b,e=this._pArmOffset+3;return{class:"",path:"M"+(t.x2+e)+",0 L"+n+",0 Q"+(t.x3+t.b)+","+t.w/2+","+n+","+t.w+" L"+(t.x2+e)+","+t.w}}}class Zs extends Vs{constructor(t,n,e){super(t,n,e),this._class="TelocentricQChromosome",this._qArmOffset=3}_getPArmShape(){var t=this._getShapeData(),n=t.x3-t.b,e=this._qArmOffset;return{class:"",path:"M"+(t.x2+e)+",0 L"+(n+e)+",0 L"+(n+e)+","+t.w+" L"+t.b+","+t.w+" Q-"+t.b+","+t.w/2+","+t.b+",0"}}_addQArmShape(t){return t.concat(this._getQArmShape())}_getQArmShape(){var t=this._getShapeData();return t.o=this._qArmOffset,[{class:"acen",path:"M"+(t.x2+2)+",1 L"+(t.x2+t.o+3.25)+",1 L"+(t.x2+t.o+3.25)+","+(t.w-1)+" L"+(t.x2+2)+","+(t.w-1)},{class:"gpos66",path:"M"+(t.x2+t.o+5)+",0 L"+(t.x2+t.o+3)+",0 L"+(t.x2+t.o+3)+","+t.w+" L"+(t.x2+t.o+5)+","+t.w,strokeWidth:.5}]}}function Ks(t,n,e,r){var o,i,a,s,c;s=Lo.select(this.selector+" defs"),c=Gs.getInstance(t),o=e*this.config.chrMargin,i=r.append("g").attr("id",t.id).attr("class","chromosome "+c.getCssClass()).attr("transform","translate(0, "+o+")"),a=Vs.getInstance(c,this.config,this).render(i,n,e),Lo.select("#"+t.id+"-chromosome-set-clippath").remove(),s.append("clipPath").attr("id",t.id+"-chromosome-set-clippath").selectAll("path").data(a).enter().append("path").attr("d",(function(t){return t.path})).attr("class",(function(t){return t.class}))}function tc(t){var n,e,r,o,i,a;if(n=t.chrIndex,o=this._layout.getChromosomeSetTranslate(n),a=this.selector+" #"+t.id+"-chromosome-set",Lo.selectAll(a+" g").remove(),0===(e=Lo.select(a)).nodes().length&&(e=Lo.select(this.selector).append("g").attr("class","chromosome-set").attr("transform",o).attr("id",t.id+"-chromosome-set")),"sex"in this.config&&2===this.config.ploidy&&this.sexChromosomes.index===n)this.drawSexChromosomes(e,n);else for(r=1,this.config.ploidy>1&&(r=this._ploidy.getChromosomesNumber(n)),i=0;i<r;i++)this.appendHomolog(t,n,i,e)}function nc(t){var n,e;this.config.taxid&&(n=t.id.split("-")[0].replace("chr",""),e=this.chromosomes[this.config.taxid][n].chrIndex,this._layout.rotate(e,e,t))}function ec(){var t,n,e,r,o,i,a;t=this.config,o=Lo.select(t.container+" svg#_ideogram"),e=Lo.select(t.container+" #_ideogramInnerWrap"),r=Lo.select(t.container+" #_ideogramMiddleWrap"),a=1===(i=t.ploidy)?i:1.12*i;let s=0;"annotationsLayout"in t&&(s=t.annotationHeight*t.numAnnotTracks),"vertical"===t.orientation&&"comparative"!==t.perspective&&"collinear"!==t.geometry&&(n=this.numChromosomes*(t.chrWidth+t.chrMargin+s),"heatmap-2d"!==t.annotationsLayout&&(n=Math.ceil(n*a/t.rows),"SmallLayout"===this._layout._class&&(n+=100),n+=35,r.style("height",this._layout.getHeight()+"px"),e.style("max-width",n+"px").style("overflow-x","scroll").style("position","absolute"),o.style("min-width",n-5+"px")))}function rc(t){var n=t._layout;Lo.selectAll(t.selector+" .chromosome-set").insert("text",":first-child").data(t.chromosomesArray).attr("class",n.getChromosomeLabelClass()).attr("transform",n.getChromosomeSetLabelTranslate()).attr("x",n.getChromosomeSetLabelXPosition()).attr("y",(function(t,e){return n.getChromosomeSetLabelYPosition(e)})).attr("text-anchor",n.getChromosomeSetLabelAnchor()).each((function(n,e){!function(t,n,e,r){var o=function(t,n,e){var r;return r=-1===t.name.indexOf(" ")?[t.name]:t.name.match(/^(.*)\s+([^\s]+)$/).slice(1).reverse(),"sex"in e.config&&2===e.config.ploidy&&n===e.sexChromosomes.index&&(r="male"===e.config.sex?["XY"]:["XX"]),r}(t,n,r);Lo.select(e).selectAll("tspan").data(o).enter().append("tspan").attr("dy",(function(t,n){return-1.2*n+"em"})).attr("x",r._layout.getChromosomeSetLabelXPosition()).attr("class",(function(t,n){var e=r.config.fullChromosomeLabels;return 1===n&&e?"italic":null})).text(String)}(n,e,this,t)}))}function oc(){rc(this),function(t){var n=t._layout;Lo.selectAll(t.selector+" .chromosome-set").each((function(e,r){Lo.select(this).selectAll(".chromosome").append("text").attr("class","chrLabel").attr("transform",n.getChromosomeSetLabelTranslate()).attr("x",(function(t,e){return n.getChromosomeLabelXPosition(e)})).attr("y",(function(t,e){return n.getChromosomeLabelYPosition(e)})).text((function(n,e){return t._ploidy.getAncestor(r,e)})).attr("text-anchor","middle")}))}(this)}function ic(t,n,e,r){var o;n-=1,o=function(t){var n,e,r;return void 0===t||!t.hasOwnProperty("x")||1===t.x&&1===t.y?(n=-8,e=-16,t={x:1,y:1},r=""):(r="scale("+t.x+","+t.y+")",n=-6,e=""===t?-16:-14),{x:n,y:e,scaleSvg:r,scale:t}}(r),"vertical"===e||""===e?function(t,n,e,r){var o,i,a,s=r.config;n=function(t,n){return(n.numAnnotTracks>1||""===n.orientation)&&(t-=1),t}(n,s),o=-4,!0===s.showBandLabels&&(o=s.chrMargin+s.chrWidth+26),i=s.chrMargin*n,s.numAnnotTracks>1==!1&&(i+=1),a=i+o,t.selectAll("text.chrLabel").attr("transform",e.scaleSvg).selectAll("tspan").attr("x",e.x).attr("y",a)}(t,n,o,this):function(t,n,e,r){var o,i,a,s=r.config;o=-s.chrWidth-2,!0===s.showBandLabels&&(o=s.chrMargin+8),i=s.annotTracksHeight,"overlay"!==s.annotationsLayout&&(i*=2),a=3-(s.chrMargin*n+o)+i,a/=e.scale.x,t.selectAll("text.chrLabel").attr("transform","rotate(-90)"+e.scaleSvg).selectAll("tspan").attr("x",a).attr("y",e.y)}(t,n,o,this)}async function ac(t){const n=await fetch("https://mygene.info/v3/query"+t);return await n.json()}function sc(t,n,e="red"){let r=null;r=Array.isArray(t.genomic_pos)?t.genomic_pos.filter(t=>t.chr in n.chromosomes[n.config.taxid])[0]:t.genomic_pos;return{name:t.symbol,chr:r.chr,start:r.start,stop:r.end,id:r.ensemblgene,color:e}}async function cc(t){this.annotDescriptions={};const n=this.selector+" .annot";document.querySelectorAll(n).forEach(t=>t.remove()),this.startHideAnnotTooltipTimeout(),document.querySelectorAll(".chromosome").forEach(t=>{t.style.cursor=""});const e=`float: left; position: relative; top: -${this.config.chrHeight+30}px; left: ${Array.from(document.querySelectorAll(".chromosome-set")).slice(-1)[0].getBoundingClientRect().right}px;`,r=`?q=symbol:${t}&species=${this.config.taxid}&fields=symbol,genomic_pos,name`,o=(await ac(r)).hits[0];this.annotDescriptions[o.symbol]=o.name;let i=[];const a=sc(o,this);i.push(a);const s=await async function(t,n){const e={},r={},o=n.config.organism.replace(/-/g," "),i="https://webservice.wikipathways.org/findInteractions"+`?query=${t.name}&format=json`,a=await fetch(i);return(await a.json()).result.forEach(n=>{if(n.species.toLowerCase()===o){const o=n.fields.right.values,i=n.fields.left.values,a=o.concat(i),s=n.name,c=n.id;a.forEach(n=>{const o=s+c;if(function(t,n){return""!==t&&!t.includes(" ")&&!t.includes("/")&&t.toLowerCase()!==n.name.toLowerCase()}(n,t)&&!(o in r)){r[o]=1;const t={name:s,pathwayId:c};n in e?e[n].push(t):e[n]=[t]}})}}),e}(a,this),c=await async function(t,n){const e=[],r=Object.keys(t);if(0===r.length)return e;const o=`?q=${r.map(t=>"symbol:"+t.trim()).join(" OR ")}&species=${n.config.taxid}&fields=symbol,genomic_pos,name`;return(await ac(o)).hits.forEach(r=>{if("genomic_pos"in r==!1)return;const o=sc(r,n,"purple");e.push(o);const i=function(t,n){let e=t.name;if(void 0!==n){const t="https://www.wikipathways.org/index.php/Pathway:",r=n.map(n=>`<a href="${`${t}${n.pathwayId}`}" target="_blank">${n.name}</a>`).join("<br/>");let o="pathway";n.length>1&&(o+="s"),e+=`\n      <br/><br/>\n      Interacts in ${o}:<br/>\n      ${r}`}return e}(r,t[r.symbol]);n.annotDescriptions[r.symbol]=i}),e}(s,this);i=i.concat(c),await async function(t,n,e){const r=e.config.taxid,o=e.config.organism.replace(/[ -]/g,"_"),i="&format=condensed&type=paralogues&target_taxon="+r;let a=`/homology/id/${t.id}?${i}`;const s=await Ideogram.fetchEnsembl(a);a="/lookup/id/"+o;const c={ids:s.data[0].homologies.map(t=>t.id),species:o,object_type:"gene"},l=await Ideogram.fetchEnsembl(a,c,"POST");return Object.entries(l).map((t,r)=>{const o=t[1];if("display_name"in o==!1)return;const i={name:o.display_name,chr:o.seq_region_name,start:o.start,stop:o.end,id:o.id,color:"pink"};n.unshift(i),e.annotDescriptions[i.name]=o.description}),n}(a,i,this),i.sort((t,n)=>n.name.length-t.name.length),this.drawAnnots(i),document.querySelector("#_ideogramLegend").style=e}function lc(t){const n=this.getScientificName(this.config.taxid),e="https://ncbi.nlm.nih.gov/gene/?term="+`(${t.name}[gene])+AND+(${n}[orgn])`,r=this.annotDescriptions[t.name].split(" [")[0];return t.displayName=`<a target="_blank" href="${e}">${t.name}</a>\n    <br/>\n    ${r}\n    <br/>`,t}const uc=[{name:"<b>Click gene to 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hc{constructor(t){this.configure=qo,this.initDrawChromosomes=li,this.onLoad=hi,this.handleRotateOnClick=ui,this.init=yi,this.finishInit=Vo,this.writeContainer=ri,this.onLoadAnnots=Wi,this.onDrawAnnots=Hi,this.processAnnotData=da,this.restoreDefaultTracks=ca,this.updateDisplayedTracks=la,this.initAnnotSettings=va,this.fetchAnnots=ba,this.drawAnnots=Ui,this.getHistogramBars=Gi,this.drawHeatmaps=Oi,this.deserializeAnnotsForHeatmap=Ri,this.fillAnnots=wa,this.drawProcessedAnnots=Qi,this.drawSynteny=sa,this.startHideAnnotTooltipTimeout=zi,this.showAnnotTooltip=Yi,this.onWillShowAnnotTooltip=ji,this.onClickAnnot=qi,this.setOriginalTrackIndexes=ua,this.afterRawAnnots=ya,this.esearch="https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?retmode=json&api_key=7e33ac6a08a6955ec3b83d214d22b21a2808",this.esummary="https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?retmode=json&api_key=7e33ac6a08a6955ec3b83d214d22b21a2808",this.elink="https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?retmode=json&api_key=7e33ac6a08a6955ec3b83d214d22b21a2808",this.getOrganismFromEutils=xa,this.getTaxids=Sa,this.getAssemblyAndChromosomesFromEutils=La,this.drawBandLabels=Ia,this.getBandColorGradients=Wa,this.processBandData=Ga,this.setBandsToShow=Ea,this.hideUnshownBandLabels=Na,this.drawBandLabelText=Fa,this.drawBandLabelStalk=Oa,this.onBrushMove=Xa,this.createBrush=$a,this.createClickCursor=Va,this.onCursorMove=Ua,this.drawSexChromosomes=Qa,this.setSexChromosomes=Ja,this.convertBpToPx=Za,this.convertPxToBp=ts,this.unpackAnnots=Ws,this.packAnnots=Hs,this.initCrossFilter=zs,this.filterAnnots=js,this.assemblyIsAccession=No,this.getDataDir=Po,this.round=Bo,this.onDidRotate=Do,this.getSvg=Eo,this.fetch=Fo,this.getTaxid=Oo,this.getCommonName=Io,this.getScientificName=Ro,this.getChromosomeModel=Ys,this.getChromosomePixels=qs,this.drawChromosomeLabels=oc,this.rotateChromosomeLabels=ic,this.appendHomolog=Ks,this.drawChromosome=tc,this.rotateAndToggleDisplay=nc,this.setOverflowScroll=ec,this.plotRelatedGenes=cc,this.configure(t)}static 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Date).getTime(),t.debug&&console.log("Time in showing bands: "+(i-o)+" ms"),"vertical"===t.orientation))for(e=0;e<n.chromosomesArray.length;e++)r="#"+n.chromosomesArray[e].id,n.rotateChromosomeLabels(Lo.select(r),e);!0===t.showChromosomeLabels&&n.drawChromosomeLabels(n.chromosomes)}(e,this),e.brush?this.createBrush(e.brush):e.cursorPosition&&this.createClickCursor(e.cursorPosition),r&&(Array.isArray(r)?this.drawAnnots(r):(this.rawAnnots=r,this.afterRawAnnots(),Uo(this))),function(t,n,e){var r=(new Date).getTime();t.debug&&console.log("Time in drawChromosome: "+(r-e)+" ms");var o=(new Date).getTime();t.debug&&console.log("Time constructing ideogram: "+(o-n)+" ms")}(e,t,n),this.setOverflowScroll(),"collinear"===e.geometry&&$o(this),this.onLoadCallback&&this.onLoadCallback()}class Qo{constructor(t){this._config=t,this._description=this._normalize(this._config.ploidyDesc)}getChromosomesNumber(t){if(this._config.ploidyDesc){var n=this._config.ploidyDesc[t];return n instanceof Object?Object.keys(n)[0].length:n.length}return this._config.ploidy||1}_normalize(t){var n,e,r=[];if(!t)return t;for(n in t)"string"==typeof(e=t[n])?("vertical"===this._config.orientation&&(e=e.split("").reverse()),r.push({ancestors:e,existence:this._getexistenceArray(e.length)})):r.push({ancestors:Object.keys(e)[0],existence:e[Object.keys(e)[0]]});return r}_getexistenceArray(t){for(var n=[],e=0;e<t;e++)n.push("11");return n}getSetSize(t){return this._description?this._description[t].ancestors.length:1}getAncestor(t,n){return this._description?this._description[t].ancestors[n]:""}exists(t,n,e){if(this._description){var r=this._description[t].existence[n][e];return Number(r)>0}return!0}}class Jo{constructor(t){this._node=t}getLabel(){return Lo.select(this._node.parentNode).select("text.chrLabel").text()}getSetLabel(){return Lo.select(this._node.parentNode).select("text.chrSetLabel").text()}}var Zo=class{constructor(t,n){if(this._config=t,this._ideo=n,this._ploidy=this._ideo._ploidy,this._translate=void 0,"chrSetMargin"in t)this.chrSetMargin=t.chrSetMargin;else{var e=this._config.chrMargin;this.chrSetMargin=this._config.ploidy>1?e:0}this._tickSize=8,this._isRotated=!1}_getLeftMargin(){return this.margin.left}_getYScale(){return 20/this._config.chrWidth}getChromosomeLabels(t){var n=new Jo(t),e=[];return this._ideo.config.ploidy>1&&e.push(n.getSetLabel()),e.push(n.getLabel()),e.filter((function(t){return t.length>0}))}getChromosomeBandLabelTranslate(t){var n,e,r,o=this._ideo,i=this._tickSize,a=o.config.orientation;return"vertical"===a?r="rotate(-90)translate("+(n=i)+","+(e=o.round(2+t.px.start+t.px.width/2))+")":"horizontal"===a&&(r="translate("+(n=o.round(-i+t.px.start+t.px.width/2))+","+(e=-10)+")"),{x:n,y:e,translate:r}}didRotate(t,n){var e,r,o,i,a,s,c,l,u;r=(e=this._ideo).config.taxid,o=n.id.split("-")[0].replace("chr",""),i=(a=e.chromosomes[r][o]).bands,l=(c=Lo.select(n.parentNode)).attr("transform"),u=/scale\(.*\)/.exec(l),l=l.replace(u,""),c.attr("transform",l),s=a.width,(a=e.getChromosomeModel(i,o,r,t)).oldWidth=s,e.chromosomes[r][o]=a,e.drawChromosome(a),e.handleRotateOnClick(),e.rawAnnots&&(e.displayedTrackIndexes?e.updateDisplayedTracks(e.displayedTrackIndexes):(e.annots=e.processAnnotData(e.rawAnnots),e.drawProcessedAnnots(e.annots),e.config.filterable&&e.initCrossFilter())),!0===e.config.showBandLabels&&(e.drawBandLabels(e.chromosomes),e.hideUnshownBandLabels()),e.onDidRotateCallback&&e.onDidRotateCallback(a)}rotate(t,n,e){var r,o,i,a;r=this._ideo,a=r.selector+" .chrSetLabel, "+r.selector+" .chrLabel",i=document.querySelector(r.selector).getBoundingClientRect(),o=Lo.selectAll(r.selector+" g.chromosome").filter((function(){return this!==e})),this._isRotated?(this._isRotated=!1,r.config.chrHeight=r.config.chrHeightOriginal,r.config.chrWidth=r.config.chrWidthOriginal,r.config.annotationHeight=r.config.annotationHeightOriginal,this.rotateBack(t,n,e,(function(){o.style("display",null),Lo.selectAll(a).style("display",null),r._layout.didRotate(n,e)}))):(this._isRotated=!0,o.style("display","none"),Lo.selectAll(a).style("display","none"),this.rotateForward(t,n,e,(function(){var t,o,a;r.config.chrHeightOriginal=r.config.chrHeight,r.config.chrWidthOriginal=r.config.chrWidth,r.config.annotationHeightOriginal=r.config.annotationHeight;"VerticalLayout"===r._layout._class?(o=i.width-20,a=window.innerWidth-20):(o=i.height-10,a=window.innerHeight-10),t=a<o?a:o,t-=2*r.config.chrMargin,r.config.chrHeight=t,r.config.chrWidth*=2.3,r.config.annotationHeight*=1.7,r._layout.didRotate(n,e)})))}getChromosomeLabelClass(){return 1===this._config.ploidy?"chrLabel":"chrSetLabel"}_getAdditionalOffset(){var t=this._config,n=t.annotationsNumTracks||t.numAnnotTracks||1;return(t.annotationHeight||0)*n}_getChromosomeSetSize(t){return this._ploidy.getSetSize(t)*this._config.chrWidth*2+this.chrSetMargin}getChromosomeSetLabelAnchor(){return"middle"}getChromosomeLabelYPosition(){return-5.5}getChromosomeSetLabelYPosition(t){return 1===this._config.ploidy?this.getChromosomeLabelYPosition(t):-2*this._config.chrWidth}};var Ko=class extends Zo{constructor(t,n){super(t,n),this._class="VerticalLayout",this.margin={top:30,left:15}}rotateForward(t,n,e,r){var o="translate(20, 25) "+this.getChromosomeScale(e);Lo.select(e.parentNode).transition().attr("transform",o).on("end",r);var i=this.getChromosomeLabels(e),a=1.3*(20+this._config.chrWidth);Lo.select(this._ideo.getSvg()).append("g").attr("class","tmp").selectAll("text").data(i).enter().append("text").attr("class",(function(t,n){return 0===n&&2===i.length?"chrSetLabel":null})).attr("x",0).attr("y",a).style("opacity",0).text(String).transition().style("opacity",1),this._ideo.config.orientation="horizontal"}rotateBack(t,n,e,r){var o=this.getChromosomeScaleBack(e),i=this.getChromosomeSetTranslate(t);Lo.select(e.parentNode).transition().attr("transform",i+" "+o).on("end",r),Lo.selectAll(this._ideo.selector+" g.tmp").style("opacity",0).remove(),this._ideo.config.orientation="vertical"}getHeight(){return this._config.chrHeight+1.5*this.margin.top}getWidth(){return"97%"}getChromosomeBandTickY1(){return 2}getChromosomeBandTickY2(){return 10}getChromosomeSetLabelTranslate(){return"rotate(-90)"}getChromosomeBandLabelAnchor(){return null}getChromosomeScale(t){var n,e;return n=Lo.select(this._ideo.selector).node().getBoundingClientRect(),e=t.getBoundingClientRect(),"scale("+n.width/e.height*.97+", "+this._getYScale()+")"}getChromosomeScaleBack(t){var n,e,r;return e=(r=this._ideo.config).taxid,n=t.id.split("-")[0].replace("chr",""),"scale("+this._ideo.chromosomes[e][n].oldWidth/(3*r.chrHeight)*.97+", "+1/this._getYScale()+")"}getChromosomeSetTranslate(t){return"rotate(90) translate("+this.margin.top+", -"+this.getChromosomeSetYTranslate(t)+")"}getChromosomeSetYTranslate(t){var n,e=this._getAdditionalOffset(),r=this._config.chrMargin,o=this._config.chrWidth;if(!this._config.ploidyDesc)return"histogram"===this._config.annotationsLayout?r+t*(r+o+3)+2*this._ideo.config.barWidth:(n=o+t*(r+o)+2*e,e>0?n:n+4+2*t);if(!this._translate){var i;this._translate=[this._ploidy.getSetSize(0)*o*2];for(var a=1;a<this._config.ploidyDesc.length;a++)i=this._translate[a-1],this._translate[a]=i+this._getChromosomeSetSize(a-1)}return this._translate[t]}getChromosomeSetLabelXPosition(){return this._config.chrWidth*this._config.ploidy/-2}getChromosomeLabelXPosition(){return this._config.chrWidth/-2}};var ti=class extends Zo{constructor(t,n){super(t,n),this._class="HorizontalLayout",this.margin={left:20,top:30}}_getLeftMargin(){var t=Zo.prototype._getLeftMargin.call(this);return this._config.ploidy>1&&(t*=1.8),t}rotateForward(t,n,e,r){var o;Lo.select(e.parentNode).transition().attr("transform","rotate(90) translate(30, -37.5) ").on("end",r),o=this.getChromosomeLabels(e),Lo.select(this._ideo.getSvg()).append("g").attr("class","tmp").selectAll("text").data(o).enter().append("text").attr("class",(function(t,n){return 0===n&&2===o.length?"chrSetLabel":null})).attr("x",26).attr("y",(function(t,n){return 12*(n+1+o.length%2)})).style("text-anchor","middle").style("opacity",0).text(String).transition().style("opacity",1),this._ideo.config.orientation="vertical"}rotateBack(t,n,e,r){var o=this.getChromosomeSetTranslate(t);Lo.select(e.parentNode).transition().attr("transform",o).on("end",r),Lo.selectAll(this._ideo.selector+" g.tmp").style("opacity",0).remove(),this._ideo.config.orientation="horizontal"}getHeight(t){void 0===t&&(t=this._config.taxids[0]);var n=this._config.chromosomes[t].length,e=this.getChromosomeSetYTranslate(n-1);return(e+=this._getChromosomeSetSize(n-1))+2*this._getAdditionalOffset()}getWidth(){return this._config.chrHeight+1.5*this.margin.top}getChromosomeSetLabelAnchor(){return"end"}getChromosomeBandLabelAnchor(){return null}getChromosomeBandTickY1(){return 2}getChromosomeBandTickY2(){return 10}getChromosomeSetLabelTranslate(){return null}getChromosomeSetTranslate(t){return"translate("+this._getLeftMargin()+", "+this.getChromosomeSetYTranslate(t)+")"}getChromosomeSetYTranslate(t){if(!this._config.ploidyDesc)return this._config.chrMargin*(t+1);if(!this._translate){this._translate=[1];for(var n=1;n<this._config.ploidyDesc.length;n++)this._translate[n]=this._translate[n-1]+this._getChromosomeSetSize(n-1)}return this._translate[t]}getChromosomeSetLabelXPosition(t){return 1===this._config.ploidy?this.getChromosomeLabelXPosition(t):-20}getChromosomeSetLabelYPosition(t){var n=this._ploidy.getSetSize(t),e=this._config,r=e.chrMargin,o=e.chrWidth;return 1===e.ploidy?o/2+3:n*r/2}getChromosomeLabelXPosition(){return-8}getChromosomeLabelYPosition(){return this._config.chrWidth}};var ni=class extends Zo{constructor(t,n){super(t,n),this._class="PairedLayout",this.margin={left:30}}getHeight(){return this._config.chrHeight+1.5*this.margin.left}getWidth(){return"97%"}getChromosomeBandTickY1(t){return t%2?this._config.chrWidth:2*this._config.chrWidth}getChromosomeBandTickY2(t){var n=this._config.chrWidth;return t%2?n-this._tickSize:2*n+this._tickSize}getChromosomeBandLabelAnchor(t){return t%2?null:"end"}getChromosomeBandLabelTranslate(t,n){var e=n%2?10:-this._config.chrWidth-10,r=this._ideo.round(t.px.start+t.px.width/2)+3;return{x:r,y:r,translate:"rotate(-90) translate("+e+", "+r+")"}}getChromosomeLabelXPosition(){return-this._tickSize}getChromosomeSetLabelXPosition(){return this._config.chrWidth/-2}getChromosomeSetLabelTranslate(){return"rotate(-90)"}getChromosomeSetTranslate(t){var n=this.getChromosomeSetYTranslate(t);return"rotate(90) translate("+this.margin.left+", -"+n+")"}getChromosomeSetYTranslate(t){return 200*(t+1)}};var ei=class extends Zo{constructor(t,n){super(t,n),this._class="SmallLayout",this.margin={left:36.5,top:10};var e=this._ideo.getTaxid(this._ideo.config.organism);this.chrs=t.chromosomes[e];var r=this.chrs.length;this.chrsPerRow=Math.ceil(r/t.rows)}getHeight(){var t=1.25*this._config.chrHeight;return this._config.rows*(t+this.margin.top)}getWidth(){return"97%"}getChromosomeBandLabelTranslate(){}getChromosomeSetLabelTranslate(){return"rotate(-90)"}getChromosomeSetTranslate(t){var n,e;return t>this.chrsPerRow-1?(n=this.margin.left+1.3*this._config.chrHeight,e=this.getChromosomeSetYTranslate(t-this.chrsPerRow)):(n=this.margin.left,e=this.getChromosomeSetYTranslate(t)),"rotate(90) translate("+n+", -"+e+")"}getChromosomeSetYTranslate(t){var n=.3*this._getAdditionalOffset();return this.margin.left*t+this._config.chrWidth+2*n+n*t}getChromosomeSetLabelXPosition(t){return(this._ploidy.getSetSize(t)*this._config.chrWidth+20)/-2+(this._config.ploidy>1?0:this._config.chrWidth)}getChromosomeLabelXPosition(){return this._config.chrWidth/-2}};function ri(t){this.config.annotationsPath&&this.fetchAnnots(this.config.annotationsPath),function(t){if("ploidyDesc"in t.config&&"string"==typeof t.config.ploidyDesc){for(var n=[],e=0;e<t.numChromosomes;e++)n.push(t.config.ploidyDesc);t.config.ploidyDesc=n}t._ploidy=new Qo(t.config)}(this),this._layout=function(t){var n=t.config;return"perspective"in n&&"comparative"===n.perspective?new ni(n,t):"rows"in n&&n.rows>1?new ei(n,t):"vertical"===n.orientation?new Ko(n,t):"horizontal"===n.orientation?new ti(n,t):new Ko(n,t)}(this),function(t){Lo.selectAll(t.config.container+" #_ideogramOuterWrap").remove(),Lo.select(t.config.container).append("div").attr("id","_ideogramOuterWrap").append("div").attr("id","_ideogramTrackLabelContainer").style("position","absolute"),Lo.select(t.config.container+" #_ideogramOuterWrap").append("div").attr("id","_ideogramMiddleWrap").style("position","relative").style("overflow-x","auto").style("transform","translateZ(0)").append("div").attr("id","_ideogramInnerWrap").append("svg").attr("id","_ideogram").attr("class",function(t){var n="";return t.config.showChromosomeLabels&&("horizontal"===t.config.orientation?n+="labeledLeft ":n+="labeled "),!1===t.config.rotatable&&(n+="no-rotate "),t.config.annotationsLayout&&"overlay"===t.config.annotationsLayout&&(n+="faint"),n}(t)).attr("width",t._layout.getWidth()).attr("height",t._layout.getHeight()).html(t.getBandColorGradients())}(this),this.isOnlyIdeogram=1===document.querySelectorAll("#_ideogram").length,function(t){Lo.select(t.config.container+" #_ideogramOuterWrap").append("div").attr("class","_ideogramTooltip").attr("id","_ideogramTooltip").style("opacity",0).style("position","fixed").style("text-align","center").style("padding","4px").style("font","12px sans-serif").style("background","white").style("border","1px solid black").style("border-radius","5px").style("z-index","9000")}(this),this.finishInit(t)}var oi="";function ii(t,n,e){return e.config.dataDir+t[n]}function ai(t,n,e){var r=e.config.ploidy;return"sex"in e.config&&(2===r&&e.sexChromosomes.index+1===n||"female"===e.config.sex&&"Y"===t.name)}function si(t,n,e,r){var o,i,a,s,c;for(o=0;o<n.length;o++)a=n[o],void 0!==t&&(i=t[o]),c=o+r.config.taxids.indexOf(e),s=r.getChromosomeModel(i,a,e,c),"string"!=typeof a&&(a=a.name.split(" ").slice(-1)[0].replace("chr","")),r.chromosomes[e][a]=s,r.chromosomesArray.push(s),ai(s,o,r)||r.drawChromosome(s)}function ci(t,n){"undefined"!=typeof chrBands&&t.length>=chrBands.length/2&&(n.coordinateSystem="bp")}function li(){var t,n,e,r,o=this.config.taxids;for(n=0;n<o.length;n++)t=o[n],e=this.config.chromosomes[t],r=this.bandsArray[t],ci(e,this),this.chromosomes[t]={},this.setSexChromosomes(e),si(r,e,t,this),this.config.showBandLabels&&this.drawBandLabels(this.chromosomes),this.handleRotateOnClick(),this._gotChrModels=!0}function ui(){var t=this;"rotatable"in t.config&&!1===t.config.rotatable?Lo.selectAll(t.selector+" .chromosome").style("cursor","default"):Lo.selectAll(t.selector+" .chromosome").on("click",(function(){t.rotateAndToggleDisplay(this)}))}function hi(){call(this.onLoadCallback)}function fi(t,n,e){var r=e.organisms[t],o=[Wo(r.scientificName)],i=r.assemblies,a=e.config.resolution;n!==i.default&&o.push(n),"9606"===t&&(n in i==="false"&&Object.values(i).includes(config.assembly)||""!==a&&850!==a)&&o.push(a),o=o.join("-");return["9606","10090","10116"].includes(t)&&!e.config.showFullyBanded&&(o+="-no-bands"),o+=".json"}function mi(t,n,e){var r,o,i,a=e.config;return r=e.organisms[t],a.assembly||(e.config.assembly="default"),o=r.assemblies,i=fi(t,e.assemblyIsAccession()?a.assembly:o[a.assembly],e),t in e.organismsWithBands&&(n[t]=i),n}function gi(t,n,e,r){return function(t,n,e){var r=ii(t,n,e);return(!(void 0!==window.chrBands&&""===oi)||oi!==r)&&function(t){return"assembly"in t.config&&!1===/(GCA_)/.test(t.config.assembly)}(e)&&n in t}(n,t,r)?function(t,n,e,r){var o=ii(t,n,r);return r.numBandDataResponses||(r.numBandDataResponses=0),fetch(o).then((function(n){return n.json().then((function(e){oi=o,delete window.chrBands,window.chrBands=e.chrBands,function(t,n,e,r){var o,i,a;for(o in n)a=n[o],t.includes(a)&&""!==a&&(i=o);r.bandData[i]=e}(n.url,t,chrBands,r)}))}))}(n,t,0,r).then((function(){return r.processBandData(t)})):new Promise((function(n){r.processBandData(t),n([t,void 0])}))}var di={},pi={},vi={};function yi(t){var n=(t=t||this).config.container;vi[n]?(pi[n]=!0,di[n]=t):(vi[n]=!0,function(t){return new Promise((function(n){if("number"==typeof t.config.organism){var e=t.config.organism;t.getOrganismFromEutils(e,(function(){t.getTaxids(n)}))}else t.getTaxids(n)}))}(t).then((function(e){var r=e[0];t.config.taxid=r,t.config.taxids=e,function(t,n,e){var r,o,i,a=[];for(i in r={},zo)r[i]="";for(o=0;o<t.length;o++)r=mi(i=String(t[o]),r,e),a.push(gi(i,r,0,e));Promise.all(a).then((function(t){var r,i,a;for(o=0;o<t.length;o++)i=(r=t[o])[0],a=r[1],"bandsArray"in e==!1&&(e.bandsArray={}),e.bandsArray[i]=a;e.writeContainer(n)}))}(e,(new Date).getTime(),t),vi[n]=!1,pi[n]&&(pi[n]=!1,yi(di[n]))})))}class bi{constructor(t,n){this.rawAnnots=this.parseBed(t,n)}static componentToHex(t){var n=parseInt(t,10).toString(16);return 1===n.length?"0"+n:n}static rgbToHex(t,n,e){return"#"+bi.componentToHex(t)+bi.componentToHex(n)+bi.componentToHex(e)}parseGenomicCoordinates(t,n){var e,r,o,i;return e=t[0],r=parseInt(t[1],10),i=(o=parseInt(t[2],10))-r,n&&(e=e.slice(3)),[e,r,o,i]}parseAnnotFromTsvLine(t,n,e){var r,o,i,a,s,c,l,u=t.split(/\s/g);return[i,a,stop,length]=this.parseGenomicCoordinates(u,e),-1===(o=n.indexOf(i))?[null,null]:(r=["",a,length,0],u.length>=4&&(l=u[3],r[0]=l),u.length>=8&&(s=u[8].split(","),c=bi.rgbToHex(s[0],s[1],s[2]),r.push(c)),[o,r])}parseRawAnnots(t,n,e,r){var o,i,a,s,c,l;for(l=!0,!1===isNaN(parseInt(e[n],10))&&(l=!1),o=n;o<e.length;o++)i=e[o],[a,s]=this.parseAnnotFromTsvLine(i,r,l),null!==a&&t[a].annots.push(s);return c=["name","start","length","trackIndex"],e[n].length>=8&&c.push("color"),{keys:c,annots:t}}parseBed(t,n){var e,r,o,i,a=[],s=t.split(/\r\n|\n/);for(r=Object.keys(n.chromosomes[n.config.taxid]),e=0;e<r.length;e++)o=r[e],a.push({chr:o,annots:[]});return i=0,("chr"===s[0].slice(0,3)||isNaN(parseInt(s[0],10)))&&(i=1),this.parseRawAnnots(a,i,s,r)}}var wi=["name","start","length","trackIndex","trackIndexOriginal","color"],_i={3:["00B","DDD","F00"],5:["00D","66D","DDD","F88","F00"],17:["00D","00D","00D","00D","00D","44D","44D","DDD","DDD","DDD","DDD","F88","F66","F22","F22","F00","F00","F00"]};function xi(t){var n,e,r;if(t.rawAnnots.metadata&&t.rawAnnots.metadata.trackLabels)n=t.rawAnnots.metadata.trackLabels;else if(t.config.heatmaps)for(n=[],e=t.config.heatmaps,r=0;r<e.length;r++)n.push(e[r].key);else n=t.rawAnnots.keys.slice(0).filter(t=>!wi.includes(t));return t.displayedTrackIndexes&&(n=n.filter((function(n,e){return t.displayedTrackIndexes.includes(e+1)}))),n}function Ai(t){var n,e,r=t.rawAnnots;if(!r.metadata||r.metadata.heatmapThresholds||t.config.heatmapThresholds)return n=t.config.heatmapThresholds?t.config.heatmapThresholds:t.rawAnnots.metadata.heatmapThresholds,e=_i[n.length+1],(n=n.map((t,n)=>[t,"#"+e[n]])).push(["+","#"+e.slice(-1)[0]]),n}function Ci(t,n,e,r,o){return t===n&&"+"===o&&e>r||e===o||0!==t&&t!==n&&e<=o&&e>r||0===t&&e<=o}function ki(t,n){var e,r,o,i,a,s,c,l;for(e=0;e<t.length;e++)r=t.length-1,i=(o=t[e])[0],a=parseFloat(i),!1===isNaN(a)&&(i=a),0!==e&&(c=parseFloat(t[e-1][0])),s=o[1],Ci(e,r,n,c,i)&&(l=s);return l}function Ti(t){!function(t,n){var e,r,o,i,a=n.config.annotLabelHeight;for(11,i=n.config.demarcateCollinearChromosomes?2:0,(o=Lo.select(n.config.container+" #_ideogramTrackLabelContainer")).html(""),r=n.config.annotationHeight+a+4,e=0;e<t.length;e++)o.style("position","absolute").append("div").attr("class","_ideogramTrackLabel").style("opacity",1).style("position","absolute").style("text-align","center").style("padding","1px").style("font","11px sans-serif").style("background","white").style("line-height","10px").style("z-index","5").style("left",11+i+"px").style("top",r*e+i+"px").style("width","max-content").style("transform-origin","bottom left").style("text-align","left").html(t[e])}(xi(t),t)}function Si(t,n,e){var r,o,i,a,s,c=t.width,l=[],u=e.config.annotLabelHeight,h=e.config.numAnnotTracks;for(r=0;r<h;r++)i=e.config.annotationHeight+u+4,s=t.id+"-canvas-"+r,o=n,t.chrIndex>0&&(o+=e.config.chrMargin*t.chrIndex-1),a=Lo.select(e.config.container+" #_ideogramInnerWrap").append("canvas").attr("id",s).attr("width",c+1).attr("height",i).style("position","absolute").style("left",o+"px").style("top",i*r+1+"px").nodes()[0].getContext("2d"),l.push([a,t]);return l}function Mi(t,n,e){var r,o,i,a,s=e.config.annotLabelHeight,c=e.config.annotationHeight,l=e.config.demarcateCollinearChromosomes,u=c+s+4;for(r=0;r<t.length;r++)if(i=n[(o=t[r]).trackIndex][0],a=n[o.trackIndex][1],i.fillStyle=o.color,l){if(o.startPx<1||o.startPx>a.width-1)continue;i.fillRect(o.startPx,1,.5,u)}else i.fillRect(o.startPx,s+1,.5,c);if(l)for(r=0;r<n.length;r++)i=n[r][0],a=n[r][1],i.fillStyle="#555",0===a.chrIndex&&i.fillRect(0,0,1,u),i.fillRect(a.width-1,0,1.1,u),i.fillRect(0,0,a.width+1,1),e.config.chrMargin&&i.fillRect(0,0,1.1,u)}function Li(t,n,e){var r,o,i,a=e.config.annotationHeight,s=e._layout.margin.top;for(i=t.values,r=0;r<i.length;r++)n.fillStyle=i[r],o=(r-1)*a,n.fillRect(o,t.startPx+s,a,2)}function Ni(t,n){var e,r,o=n.config.container,i=n._layout.margin.top,a=n.config.chrHeight+i,s=n.config.annotationHeight*t[0].values.length;for(Lo.selectAll(o+" canvas").remove(),Lo.select(o+" #_ideogramInnerWrap").style("max-width",s+"px"),Lo.select(o+" 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Ii(t,n,e){var r,o,i,a,s,c,l,u=[];for(r=0;r<n.length;r++)for(i=n[r],o=0;o<t.length;o++)a=i.slice(0,3),s=i[t[o]],c=ki(e.config.heatmaps[o].thresholds,s),l=o,a.push(l,c,s),u.push(a);return u}function Ri(t){var n,e,r,o,i=(new Date).getTime(),a=t.keys,s=t.annots;for(r=[],o=0;o<this.config.heatmaps.length;o++)e=this.config.heatmaps[o].key,r.push(a.indexOf(e));n=function(t,n,e){var r,o,i,a,s=[];for(a=0;a<n.length;a++)o=(r=n[a]).chr,i=Ii(t,r.annots,e),s.push({chr:o,annots:i});return s}(r,s,this),a.splice(3,0,"trackIndex"),a.splice(4,0,"color"),this.rawAnnots.keys=a,this.rawAnnots.annots=n,function(t,n){var e=(new Date).getTime();n.config.debug&&console.log("Time in deserializeAnnotsForHeatmap: "+(e-t)+" ms")}(i,this)}function Wi(){call(this.onLoadAnnotsCallback)}function Hi(){call(this.onDrawAnnotsCallback)}function 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r,o,i;for(r=0;r<e.rows.length;r++)t+="<li>"+(i=e.rows[r]).name+"</li>",o=19*r,"name"in e&&(o+=19),n+='<g transform="translate(0, '+o+')">'+Xi(i)+"</g>";return[t,n]}function Ui(t){var n,e,r=[],o=this.chromosomes[this.config.taxid];if("annots"in t[0]||"values"in t[0])return this.drawProcessedAnnots(t);for(e in o)r.push({chr:e,annots:[]});r=function(t,n){var e,r,o,i;for(e=0;e<t.length;e++)for(o=t[e],r=0;r<n.length;r++)if(o.chr===n[r].chr){i=[o.name,o.start,o.stop-o.start],"color"in o&&i.push(o.color),"shape"in o&&i.push(o.shape),n[r].annots.push(i);break}return n}(t,r),n=function(t){var n=["name","start","length"];return"color"in t[0]&&n.push("color"),"shape"in t[0]&&n.push("shape"),n}(t),this.rawAnnots={keys:n,annots:r},this.annots=this.processAnnotData(this.rawAnnots),this.drawProcessedAnnots(this.annots)}function Vi(t,n,e){var r;!function(t,n){var e,r;if(!/heatmap/.test(t)&&"histogram"!==t){for(r=0,e=0;e<n.length;e++)r+=n[e].annots.length;r>2e3&&console.warn('Rendering more than 2000 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Ki(t,n,e,r,o,i){var a,s;a="color"in i?i.color:"#CFC",s="opacity"in i?i.opacity:1,t.append("polygon").attr("points",r.startPx-15+", "+n+" "+(r.stopPx-15)+", "+n+" "+(o.stopPx-15)+", "+e+" "+(o.startPx-15)+", "+e).style("fill",a).style("fill-opacity",s)}function ta(t,n,e=null){var r,o,i,a;if(r=t.r1,o=t.r2,"string"==typeof r.chr){const t=n.config.taxids;n.config.multiorganism?(r.chr=n.chromosomes[t[0]][r.chr],o.chr=n.chromosomes[t[1]][o.chr]):(r.chr=n.chromosomes[t[0]][r.chr],o.chr=n.chromosomes[t[0]][o.chr])}var s=document.querySelector("#"+r.chr.id+"-chromosome-set"),c=s.getCTM().e,l=s.getCTM().f,u=document.querySelector("#"+o.chr.id+"-chromosome-set"),h=u.getCTM().e,f=u.getCTM().f;return null===e?"vertical"===n.config.orientation?(i=l-12,a=f-12):(i=c,a=h):(i=e,a=e),r.startPx=n.convertBpToPx(r.chr,r.start)+i,r.stopPx=n.convertBpToPx(r.chr,r.stop)+i,o.startPx=n.convertBpToPx(o.chr,o.start)+a,o.stopPx=n.convertBpToPx(o.chr,o.stop)+a,[r,o]}function na(t,n,e,r,o){t.append("line").attr("class","syntenyBorder").attr("x1",n).attr("x2",e).attr("y1",r.startPx).attr("y2",o.startPx),t.append("line").attr("class","syntenyBorder").attr("x1",n).attr("x2",e).attr("y1",r.stopPx).attr("y2",o.stopPx)}function ea(t,n){var e=(new Date).getTime();(function(t,n,e){var r,o,i,a,s,c,l,u;for(r=0;r<t.length;r++)o=t[r],[i,a]=ta(o,e),Zi(s=Ji(n,i.chr.id+"_"+i.start+"_"+i.stop+"___"+a.chr.id+"_"+a.start+"_"+a.stop,e),l=(c=e.config.chrWidth)+46,u=c+240,i,a,o),na(s,l,u,i,a)})(t,Lo.select(n.selector).insert("g",":first-child").attr("class","synteny"),n),function(t,n){var e=(new Date).getTime();n.config.debug&&console.log("Time in drawSyntenicRegions: "+(e-t)+" ms")}(e,n)}function ra(t,n,e,r,o){t.append("line").attr("class","syntenyBorder").attr("x1",r.startPx-15).attr("x2",o.startPx-15).attr("y1",n).attr("y2",e),t.append("line").attr("class","syntenyBorder").attr("x1",r.stopPx-15).attr("x2",o.stopPx-15).attr("y1",n).attr("y2",e)}function oa(t,n){var e=(new Date).getTime();(function(t,n,e){var r,o,i,a,s,c,l,u;for(r=0;r<t.length;r++)o=t[r],[i,a]=ta(o,e),Ki(s=Ji(n,i.chr.id+"_"+i.start+"_"+i.stop+"___"+a.chr.id+"_"+a.start+"_"+a.stop,e),l=(c=e.config.chrWidth)+31,u=c+191,i,a,o),ra(s,l,u,i,a)})(t,Lo.select(n.selector).insert("g",":first-child").attr("class","synteny"),n),function(t,n){var e=(new Date).getTime();n.config.debug&&console.log("Time in drawSyntenicRegions: "+(e-t)+" ms")}(e,n)}function ia(t,n,e,r,o,i){var a,s;Math.abs(r.startPx-r.startPx)<2&&Math.abs(r.stopPx-r.stopPx)<2?(a=i.color,s=i.width):(a="",s=""),t.append("line").attr("class","syntenyBorder").attr("x1",n).attr("x2",e).attr("y1",r.startPx).attr("y2",o.startPx).style("stroke",a).style("stroke-width",s),t.append("line").attr("class","syntenyBorder").attr("x1",n).attr("x2",e).attr("y1",r.stopPx).attr("y2",o.stopPx).style("stroke",a).style("stroke-width",a)}function aa(t,n,e,r,o,i){var a=i.split("__").map(t=>"label_"+t);if("name"in r){t.append("text").attr("id",a[0]).attr("y",r.startPx+3).text(r.name);var s=document.querySelector("#"+a[0]).getBoundingClientRect().width;Lo.select("#"+a[0]).attr("x",n-15-s)}"name"in o&&t.append("text").attr("id",a[1]).text(o.name).attr("x",e+15).attr("y",o.startPx+3).text(o.name)}function sa(t){var n=(new Date).getTime(),e=this.config;if(e.multiorganism&&"collinear"===e.geometry)return"vertical"===e.orientation?ea(t,this):oa(t,this);(function(t,n,e,r){var o,i,a,s,c,l,u,h,f;for(o=0;o<t.length;o++)i=t[o],[a,s]=ta(i,r,e),l=Ji(n,c=a.chr.id+"_"+a.start+"_"+a.stop+"___"+s.chr.id+"_"+s.start+"_"+s.stop,r),u=r.config.chrWidth,Zi(l,h=r._layout.getChromosomeSetYTranslate(0),f=r._layout.getChromosomeSetYTranslate(1)-u,a,s,i),ia(l,h,f,a,s,i),aa(l,h,f,a,s,c)})(t,Lo.select(this.selector).insert("g",":first-child").attr("class","synteny"),this._layout.margin.left,this),function(t,n){var e=(new Date).getTime();n.config.debug&&console.log("Time in drawSyntenicRegions: "+(e-t)+" ms")}(n,this)}function ca(){this.config.numAnnotTracks=this.config.annotationsNumTracks,Lo.selectAll(this.selector+" .annot").remove(),this.drawAnnots(this.processAnnotData(this.rawAnnots))}function la(t){var n,e,r,o=this.rawAnnots.annots;return this.config.numAnnotTracks=t.length,n=function(t,n){var e,r,o,i,a,s,c;for(r=[],i=0;i<t.length;i++){for(o=t[i],a=[],s=0;s<o.annots.length;s++)c=(e=o.annots[s].slice())[3]+1,n.includes(c)&&(e[3]=n.indexOf(c),a.push(e));r.push({chr:o.chr,annots:a})}return r}(o,t),r={keys:this.rawAnnots.keys,annots:n},"collinear"===this.config.geometry&&$o(this),e=this.processAnnotData(r),Lo.selectAll(this.selector+" .annot").remove(),this.displayedTrackIndexes=t,this.drawAnnots(e),e}function ua(t){var n,e;return(n=t.keys).length<4||"trackIndex"!==n[3]||"trackIndexOriginal"===n[4]||(e=function(t,n){var e,r,o,i,a,s,c,l=[];for(c=1,e=0;e<t.length;e++){for(o=t[e],a=[],r=0;r<o.annots.length;r++)(s=(i=o.annots[r].slice())[3])+1>c&&(c=s+1),i.splice(4,0,s),a.push(i);l.push({chr:o.chr,annots:a})}return n.numAvailTracks=c,l}(t.annots,this),n.splice(4,0,"trackIndexOriginal"),t={keys:n,annots:e},this.rawAnnots.metadata&&(t.metadata=this.rawAnnots.metadata)),t}var ha=[["F00"],["F00","88F"],["F00","CCC","88F"],["F00","FA0","0AF","88F"],["F00","FA0","CCC","0AF","88F"],["F00","FA0","875","578","0AF","88F"],["F00","FA0","875","CCC","578","0AF","88F"],["F00","FA0","7A0","875","0A7","578","0AF","88F"],["F00","FA0","7A0","875","CCC","0A7","578","0AF","88F"],["F00","FA0","7A0","875","552","255","0A7","578","0AF","88F"]];function fa(t,n,e,r,o,i,a){return a.config.annotationTracks?o=function(t,n,e,r,o){var i;return n.trackIndex=e[3],(i=o.config.annotationTracks[n.trackIndex]).color&&(n.color=i.color),i.shape&&(n.shape=i.shape),t[r].annots.push(n),t}(o,t,e,i,a):"trackIndex"===n[3]&&1!==a.numAvailTracks?[o,r]=function(t,n,e,r,o,i){var a=ha[i.numAvailTracks-1];return t.trackIndex=n[3],t.trackIndexOriginal=n[4],t.color="#"+a[t.trackIndexOriginal],t.trackIndex>i.config.numTracks-1?(t.trackIndex in e?e[t.trackIndex].push(t):e[t.trackIndex]=[t],[r,e]):(r[o].annots.push(t),[r,e])}(t,e,r,o,i,a):o=function(t,n,e,r){return n.trackIndex=0,n.color||(n.color=r.config.annotationsColor),n.shape||(n.shape="triangle"),t[e].annots.push(n),t}(o,t,i,a),[o,r]}function ma(t,n,e,r,o,i,a){var s,c,l,u;for(s=0;s<e.annots.length;s++){for(u=e.annots[s],l={},c=0;c<i.length;c++)l[i[c]]=u[c];l.stop=l.start+l.length,l.chr=e.chr,l.chrIndex=o,l.startPx=a.convertBpToPx(r,l.start),l.stopPx=a.convertBpToPx(r,l.stop),l.px=Math.round((l.startPx+l.stopPx)/2),[t,n]=fa(l,i,u,n,t,o,a)}return[t,n]}function ga(t){console.warn('Chromosome "'+t.chr+'" undefined in ideogram; '+t.annots.length+" annotations not shown")}function da(t){var n,e,r;return n=t.keys,t=t.annots,[e,r]=function(t,n,e){var r,o,i,a,s=[],c={};for(r=-1,o=0;o<t.length;o++)i=t[o],void 0!==(a=e.chromosomes[e.config.taxid][i.chr])?(r++,s.push({chr:i.chr,annots:[]}),"heatmap-2d"!==e.config.annotationsLayout?[s,c]=ma(s,c,i,a,r,n,e):[s,c]=Pi(s,c,i,a,r,n,e)):ga(i);return[s,c]}(t,n,this),e=function(t,n){var e,r,o,i,a,s;for(e=t,t=[],s=n.chromosomesArray,r=0;r<s.length;r++)for(a=s[r].name,o=0;o<e.length;o++)(i=e[o]).chr===a&&t.push(i);return t}(e,this),function(t,n){var e,r=n.config.annotationsLayout,o=n.config.numAnnotTracks;!/heatmap/.test(r)&&o>10&&console.error("Ideogram only displays up to 10 tracks at a time.  You specified "+o+" tracks.  Perhaps consider a different way to visualize your data."),(e=Object.keys(t).length)&&console.warn("Ideogram configuration specified "+o+" tracks, but loaded annotations contain "+e+" extra tracks.")}(r,this),e}class pa{constructor(t,n){this.matrix=t,this.ideo=n}setRawAnnots(){var t,n,e;return t=this,n=this.ideo,e=this.matrix,new Promise((function(r){t.rawAnnots=t.fetchCoordinates(n).then((function(o){t.coordinates=o,r(t.parseExpressionMatrix(e,n))}))}))}fetchCoordinates(t){var n={};if("human"===t.config.organism){var e=t.config.dataDir+"../../annotations/Homo_sapiens,_Ensembl_80.tsv";return new Promise((function(r){t.fetch(e,"text").then((function(t){var e,o,i,a,s,c,l,u;for(e=t.split(/\r\n|\n/).slice(1),o=0;o<e.length;o++)[i,a,s,u,c]=e[o].split(/\s/g),i=parseInt(i),l=(a=parseInt(a))-i,n[s]=[c,i,l];r(n)}))}))}throw Error("Expression matrix parsing is only supported for human")}parseAnnotFromTsvLine(t,n){var e,r,o,i,a,s=t.split(/\s/g);return(i=s[0])in this.coordinates==!1?[null,null]:(a=s.slice(1).map(t=>parseFloat(t)),[r,o,length]=this.coordinates[i],-1===(e=n.indexOf(r))?[null,null]:[e,[i,o,length].concat(a)])}parseExpressionMatrix(t,n){var e,r,o,i,a,s,c=[],l=t.split(/\r\n|\n/);for(r=Object.keys(n.chromosomes[n.config.taxid]),e=0;e<r.length;e++)c.push({chr:r[e],annots:[]});for(e=1;e<l.length;e++)i=l[e],[a,s]=this.parseAnnotFromTsvLine(i,r),null!==a&&c[a].annots.push(s);return o=l[0].split(/\s/g),{keys:["name","start","length"].concat(o),annots:c}}}function va(){var t=this.config;!function(t){var n,e=t.config;e.annotationHeight||("heatmap"===e.annotationsLayout?n=e.chrWidth-1:(n=Math.round(e.chrHeight/100))<3&&(n=3),t.config.annotationHeight=n)}(this),t.annotationsPath||t.localAnnotationsPath||this.annots||t.annotations?function(t,n){n.annotationTracks?t.config.numAnnotTracks=n.annotationTracks.length:n.annotationsNumTracks?t.config.numAnnotTracks=n.annotationsNumTracks:t.config.numAnnotTracks=1,t.config.annotTracksHeight=n.annotationHeight*n.numAnnotTracks,void 0===n.barWidth&&(t.config.barWidth=3)}(this,t):(this.config.annotTracksHeight=0,this.config.numAnnotTracks=0),void 0===t.annotationsColor&&(this.config.annotationsColor="#F00"),t.onClickAnnot&&(this.onClickAnnotCallback=t.onClickAnnot),function(t,n){!1!==n.showAnnotTooltip&&(t.config.showAnnotTooltip=!0),n.onWillShowAnnotTooltip&&(t.onWillShowAnnotTooltipCallback=n.onWillShowAnnotTooltip)}(this,t)}function ya(){var t=this.config;this.rawAnnots.annots=this.rawAnnots.annots.sort((function(t,n){return t.chr.localeCompare(n.chr,"en",{numeric:!0})})),this.onLoadAnnotsCallback&&this.onLoadAnnotsCallback(),("heatmapThresholds"in t||"metadata"in this.rawAnnots&&"heatmapThresholds"in this.rawAnnots.metadata)&&("heatmap"===t.annotationsLayout?function(t){var n,e,r,o,i,a,s=t.config.heatmapThresholds;for(r=[],e=(i=t.rawAnnots).keys.slice(3),o=[],a=[],!i.metadata&&isNaN(s[0])||(s=Ai(t)),n=0;n<e.length;n++)r.push({key:e[n],thresholds:s}),o.push({id:e[n]}),a.push(n+1);t.config.annotationsNumTracks=e.length,t.config.annotationsDisplayedTracks=a,t.config.heatmaps=r,t.config.annotationTracks=o}(this):"heatmap-2d"===t.annotationsLayout&&(this.config.heatmapThresholds=Ai(this))),t.heatmaps&&this.deserializeAnnotsForHeatmap(this.rawAnnots)}function ba(t){var n,e,r=this,o=r.config;e="heatmap-2d"===o.annotationsLayout,"http"===t.slice(0,4)||e?(n=e?"":function(t){var n,e;return"bed"!==(e=(n=t.split("?")[0].split("."))[n.length-1])&&"json"!==e?(e=e.toUpperCase(),void alert("Ideogram.js only supports BED and Ideogram JSON at the moment.  Sorry, check back soon for "+e+" support!")):e}(t),r.fetch(t,"text").then((function(t){(r.rawAnnotsResponse=t,e)?new pa(t,r).setRawAnnots().then((function(t){r.rawAnnots=t,r.afterRawAnnots()})):(r.rawAnnots="bed"===n?new bi(t,r).rawAnnots:JSON.parse(t),r.afterRawAnnots())}))):r.fetch(t).then((function(t){r.rawAnnotsResponse=t,r.rawAnnots=t,r.afterRawAnnots()}))}function wa(t){var n,e,r,o,i,a,s;for(n=[],e=[],r=this.chromosomesArray,o=0;o<r.length;o++)i=r[o].name,e.push(i),n.push({chr:i,annots:[]});for(o=0;o<t.length;o++)a=t[o],-1!==(s=e.indexOf(a.chr))&&(n[s]=a);return n}function _a(t,n){var e,r;return e=n.esearch+"&db=taxonomy&term="+t,Lo.json(e).then((function(n){return r=n.esearchresult.idlist[0],[t,r]}))}function xa(t,n){var e,r,o=this;t=o.config.organism,r=o.esummary+"&db=taxonomy&id="+t,Lo.json(r).then((function(r){return e=r.result[String(t)].commonname,o.config.organism=e,n(e)}))}function Aa(t,n,e){var r,o,i,a,s,c=e.config;(function(t,n){var e,r,o;if(n.assemblyIsAccession())return new Promise((function(e){n.coordinateSystem="bp",n.getAssemblyAndChromosomesFromEutils(t,e)}));e=n.config.dataDir,r=Wo(n.organisms[t].scientificName),o=[t],["9606","10090","10116"].includes(t)&&!n.config.showFullyBanded&&(r+="-no-bands");var i=e+r+".json";return new Promise((function(t,n){fetch(i).then((function(e){if(!1!==e.ok)return e.json().then((function(n){t(n.chrBands)}));n(Error("Fetch failed for "+i))}))})).then((function(e){var r,i,a,s,c=[""],l=[],u={};n.bandData[t]=e;for(var h=0;h<e.length;h++)r=(a=e[h].split(" "))[0],s=a.slice(-1)[0],r in u||(l.push({name:r,type:"nuclear",length:s}),u[r]=1);return l=l.sort(Ideogram.sortChromosomes),i={bp:0,iscn:0},l.forEach(t=>{t.length>i.bp&&(i.bp=t.length)}),n.maxLength[t]=i,c.push(l),c.push(o),c}),(function(){return new Promise((function(e){n.coordinateSystem="bp",n.getAssemblyAndChromosomesFromEutils(t,e)}))}))})(t,e).then((function(l){r=l[0],o=l[1],"chromosomes"in c==!1||null===c.chromosomes?(e.config.chromosomes={},e.config.chromosomes[t]=o):(c.multiorganism?t in c.chromosomes?i=c.chromosomes[t]:(a=Wo(e.getScientificName(t)),e.config.chromosomes[t]=c.chromosomes[a].slice(),i=e.config.chromosomes[t]):i=c.chromosomes,s=o.filter(t=>i.includes(t.name)),e.config.chromosomes[t]=s),e.chromosomes[t]=e.config.chromosomes[t].slice(),e.organisms[t].assemblies={default:r},n()}))}function Ca(t,n){var e,r;for(e in n.organisms)if(r=n.organisms[e],e===Wo(t)||Wo(r.commonName)===Wo(t)||Wo(r.scientificName)===Wo(t))return!0;return!1}function ka(t){var n,e,r,o,i,a=t.config;return n=[],e={},function(t,n){var e,r,o,i=[],a={};for(o=0;o<t.length;o++)r=!1===Ca(e=t[o],n)?_a(e,n).then((function(t){var e,r,o=t[1];r=(e=t[0].replace("-"," "))[0].toUpperCase()+e.slice(1),a[o]={scientificName:r,commonName:"",assemblies:{default:""}},Object.assign(n.organisms,a)})):new Promise((function(t){var r=n.getTaxid(e);a[r]=n.organisms[r],t()})),i.push(r);return Promise.all(i).then((function(){return a}))}(a.multiorganism?a.organism:[a.organism],t).then((function(t){var s=t[o];for(o in t)s=t[o],n.push(o),a.multiorganism&&(void 0!==a.chromosomes?((i=Object.keys(a.chromosomes).map(t=>Wo(t))).includes(Wo(s.scientificName))?r=s.scientificName:i.includes(Wo(s.commonName))&&(r=s.commonName),Wo(r)in a.chromosomes?e[o]=a.chromosomes[Wo(r)]:e[o]=a.chromosomes[r.toLowerCase()]):e=null);return[e,n]}))}function Ta(t,n){ka(n).then((function([e,r]){var o,i,a,s,c,l=n.config,u=[];for(o=0;o<r.length;o++)i=r[o],s=n.organisms[i].assemblies,c=Object.values(s),""===s.default||n.assemblyIsAccession()&&!c.includes(l.assembly)?a=new Promise((function(t){Aa(i,t,n)})):(n.config.taxids=r,n.config.multiorganism&&(n.config.chromosomes=e),a=new Promise((function(t){t()}))),u.push(a);Promise.all(u).then((function(){return r=function(t){var n,e,r;if(n=t.config.organism,e=[],Array.isArray(n))for(r=0;r<n.length;r++)e.push(t.getTaxid(n[r]));else e.push(t.getTaxid(n));return e}(n),n.config.taxids=r,t(r)}))}))}function Sa(t){var n;n="taxid"in this.config,this.config.multiorganism=function(t,n){return"organism"in n.config&&n.config.organism instanceof Array||t&&n.config.taxid instanceof Array}(n,this),this.config.multiorganism&&(this.coordinateSystem="bp"),"organism"in this.config?Ta(t,this):function(t,n,e){var r;e.config.multiorganism?t&&(r=e.config.taxid):(t&&(r=[e.config.taxid]),e.config.taxids=r),n(r)}(n,t,this)}function Ma(t,n){var e,r;return[e,r]=function(t,n){var e=t.genome;return"mitochondrion"===e?function(t,n){var e,r;return n.config.showNonNuclearChromosomes?(e=t.genome,[-1===(r=t.subtype.split("|").indexOf("plasmid"))?"MT":t.subname.split("|")[r],e]):[null,null]}(t,n):"chloroplast"===e||"plastid"===e?function(t){return t.config.showNonNuclearChromosomes?["CP","chloroplast"]:[null,null]}(n):"apicoplast"===e?function(t){return t.config.showNonNuclearChromosomes?["AP","apicoplast"]:[null,null]}(n):function(t){var n,e;return"nuclear",n=t.subtype.split("|").indexOf("chromosome"),void 0!==(e=t.subname.split("|")[n])&&"chr"===e.substr(0,3)&&(e=e.substr(3)),[e,"nuclear"]}(t)}(t,n),{name:e,length:t.slen,type:r}}function La(t,n){var e,r=this,o=function(t,n){var e;return e=n.assemblyIsAccession()?n.config.assembly+"%22[Assembly%20Accession]":t+"%22[taxid]AND%20(%22latest%20refseq%22[filter])%20",n.esearch+"&db=assembly&term=%22"+e+"AND%20(%22chromosome%20level%22[filter]%20OR%20%22complete%20genome%22[filter])"}(t,r);Lo.json(o).then((function(t){return function(t,n){var e,r;return e=t.esearchresult.idlist[0],r=n.esummary+"&db=assembly&id="+e,Lo.json(r)}(t,r)})).then((function(t){var n=t.result.uids[0];return e=t.result[n],function(t,n){var e;return e="&db=nuccore&dbfrom=assembly&linkname=assembly_nuccore&cmd=neighbor_history&from_uid="+t,Lo.json(n.elink+e).then((function(t){var r=t.linksets[0].webenv;return e="&db=nuccore&term=%231+AND+%28sequence_from_chromosome[Properties]+OR+sequence_from_plastid[Properties]+OR+sequence_from_mitochondrion[Properties]%29&WebEnv="+r+"&usehistory=y&retmax=1000",n.esearch+e}))}(n,r)})).then((function(t){return Lo.json(t)})).then((function(t){return function(t,n){var e,r;return e=t.esearchresult.idlist.join(","),r=n.esummary+"&db=nucleotide&id="+e,Lo.json(r)}(t,r)})).then((function(o){var i=function(t,n,e){var r,o,i,a,s={},c=[];for(r in t)"uids"!==r&&(i=(o=Ma(t[r],e)).name+"_"+o.length,null!==o.type&&i in s==!1&&c.push(o),s[i]=1);return c=c.sort(Ideogram.sortChromosomes),a={bp:0,iscn:0},c.forEach(t=>{t.length>a.bp&&(a.bp=t.length)}),a.bp>e.maxLength.bp&&(e.maxLength.bp=a.bp),e.maxLength[n]=a,e.coordinateSystem="bp",c}(o.result,t,r);return n([e,i])}),(function(t){console.warn(t)}))}function Na(){var t=this.bandsToShow.join(",");Lo.selectAll(this.selector+" .bandLabel, .bandLabelStalk").style("display","none"),Lo.selectAll(t).style("display","")}function 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t,n,e=[],r=this.annots;for(n=0;n<r.length;n++)t=r[n].annots,e=e.concat(t);return e}function Hs(t){var n,e,r,o=[],i=this.annots;for(n in i)o.push({chr:i[n].chr,annots:[]});for(r=0;r<t.length;r++)o[(e=t[r]).chrIndex].annots.push(e);return o}function zs(){var t,n,e=this.rawAnnots.keys;for(this.unpackedAnnots=this.unpackAnnots(),this.crossfilter=Es(this.unpackedAnnots),this.annotsByFacet={},this.facets=e.slice(3,e.length),t=0;t<this.facets.length;t++)n=this.facets[t],this.annotsByFacet[n]=this.crossfilter.dimension((function(t){return t[n]}));"filterSelections"in this&&this.filterAnnots(this.filterSelections),this.filteredAnnots=this.annots}function js(t){var n,e,r,o=Date.now();for(this.filterSelections=t,[e,r]=function(t,n){var e,r,o,i,a,s={};if(0===Object.keys(t).length)i=n.unpackedAnnots;else{for(r=0;r<n.facets.length;r++)(o=n.facets[r])in t?(a=t[o],e=Array.isArray(a)?function(t){return 2===a.length?a[0]<=t&&t<a[1]:4===a.length?a[0]<=t&&t<a[1]||a[2]<=t&&t<a[3]:void 0}:function(t){return t in a}):e=null,n.annotsByFacet[o].filter(e),s[o]=n.annotsByFacet[o].group().top(1/0);i=n.annotsByFacet[o].top(1/0)}return[i,s]}(t,this);n<this.facets.length;n++)this.annotsByFacet[void 0].filterAll();return e=this.packAnnots(e),delete this.maxAnnotsPerBar,delete this.maxAnnotsPerBarAllChrs,this.filteredAnnots=e,Lo.selectAll(this.selector+" polygon.annot").remove(),this.drawAnnots(e),console.log("Time in filterAnnots: "+(Date.now()-o)+" ms"),r}function qs(t){var n,e,r,o,i,a=t.id.split("-")[1];return n=t.bands,e=this.config.chrHeight,r=0,(o=void 0!==n)?[n,t,r]=function(t,n,e,r){var o,i,a,s,c,l=0,u=n.id.split("-")[1],h=r.coordinateSystem,f=r.config.chrHeight;for(o=0;o<t.length;o++)a=(i=t[o])[h].stop-i[h].start,r._layout._isRotated?s=f*a/n.length:(c="relative"===r.config.chromosomeScale?r.maxLength[u][h]:r.maxLength[h],s=f*n.length/c*a/n.length),t[o].px={start:l,stop:l+s,width:s},l=t[o].px.stop,e&&"acen"===i.stain&&"p"===i.name[0]&&(n.pcenIndex=o);return[t,n,l]}(n,t,o,this):(i="relative"===this.config.chromosomeScale?this.maxLength[a][this.coordinateSystem]:this.maxLength[this.coordinateSystem],r=e*t.length/i),t.width=r,t.scale=function(t,n,e){var r=e.config.chrHeight,o=t.length,i=e.maxLength,a=t.id.split("-")[1],s={};return s.bp=r/i.bp,!0===e.config.multiorganism?"relative"===e.config.chromosomeScale?(s.iscn=r*o/i[a].bp,s.bp=r/i[a].bp):s.iscn=r*o/i.bp:n&&(s.iscn=r/i.iscn),s}(t,o,this),t.bands=n,t}function Ys(t,n,e,r){var o,i,a={};return o=void 0!==t,(a=function(t,n,e,r){return void 0!==n?(t.name=e,t.length=n[n.length-1][r.coordinateSystem].stop,t.type="nuclear"):t=e,t}(a,t,n,this)).chrIndex=r,a.id="chr"+a.name+"-"+e,!0===this.config.fullChromosomeLabels&&(i=this.organisms[e],a.name=i.scientificName+" chr"+a.name),a.bands=t,(a=this.getChromosomePixels(a)).centromerePosition=function(t,n){const e=t&&"p"===n[0].name[0]&&"q"===n[1].name[0]&&n[0].bp.stop-n[0].bp.start<2e6;let r=!1;if(t){const e=n.slice(-1)[0],o=n.slice(-2)[0];r=t&&"p"===o.name[0]&&"q"===e.name[0]&&e.bp.stop-e.bp.start<2e6}return e?"telocentric-p":r?"telocentric-q":""}(o,t),a=function(t,n){return n&&1===t.bands.length&&delete t.bands,t}(a,o)}class Gs{constructor(t){this._model=t,this._class="ModelAdapter"}static getInstance(t){return t.bands?new Gs(t):new Xs(t)}getModel(){return this._model}getCssClass(){return""}}class Xs extends Gs{constructor(t){super(t),this._class="ModelNoBandsAdapter"}getModel(){return this._model.bands=[],this._model.width>1&&this._model.bands.push({name:"q",px:{start:0,stop:this._model.width,width:this._model.width},bp:{start:1,stop:this._model.length}}),this._model}getCssClass(){return"noBands"}}class $s{constructor(t){this._config=t,this._ploidy=new Qo(this._config)}getArmColor(t,n,e){return this._config.armColors?this._config.armColors[e]:this._config.ancestors?this._getPolyploidArmColor(t,n,e):null}getBorderColor(t,n,e){return n<this._config.ploidy||this._ploidy.exists(t,n,e)?"#000":"#fff"}_getPolyploidArmColor(t,n,e){if(this._ploidy.exists(t,n,e)){var r=this._ploidy.getAncestor(t,n,e);return this._config.ancestors[r]}return"transparent"}}class Us{constructor(t){this._data=t,this.start=t.start,this.stop=t.stop,this.length=this.stop-this.start}getColor(t){return"ploidy"in this._data?"ploidy"in this._data&&this._data.ploidy[t]?this._getColor(t):"transparent":this._getColor(t)}_getColor(t){return Array.isArray(this._data.color)?this._data.color[t]:this._data.color}}class Vs{constructor(t,n,e){this._adapter=t,this._model=this._adapter.getModel(),this._config=n,this._ideo=e,this._color=new $s(this._config),this._bumpCoefficient=5}static getInstance(t,n,e){const r=t.getModel().centromerePosition;return"telocentric-p"===r?new Js(t,n,e):"telocentric-q"===r?new Zs(t,n,e):new Qs(t,n,e)}_addPArmShape(t,n){return n?t.concat(this._getPArmShape()):t}_addQArmShape(t,n){return n?t.concat(this._getQArmShape()):t}render(t,n,e){var r,o,i,a,s,c,l;return r=this,t=t.append("g").attr("class","bands").attr("clip-path","url(#"+this._model.id+"-chromosome-set-clippath)"),o=this._renderArm(t,n,e,"p"),i=this._renderArm(t,n,e,"q"),this._renderRangeSet(t,n,e),a=[],a=this._addPArmShape(a,o),a=this._addQArmShape(a,i),s="0",c="",l=this.isFullyBanded(),"ancestors"in this._ideo.config&&!("rangeSet"in this._ideo.config)?(c=r._color.getArmColor(n,e,0),l&&(s="0.5")):l?(s=null,c="transparent"):"ancestors"in this._ideo.config||(s="1"),t.append("g").attr("class","chromosome-border").selectAll("path").data(a).enter().append("path").attr("fill",c).style("fill-opacity",s).attr("stroke",(function(t,o){return r._color.getBorderColor(n,e,o)})).attr("stroke-width",(function(t){return"strokeWidth"in t?t.strokeWidth:1})).attr("d",(function(t){return t.path})).attr("class",(function(t){return t.class})),a}_renderRangeSet(t,n,e){var r,o,i,a;"rangeSet"in this._config&&(o=this._config.rangeSet.filter((function(t){return t.chr-1===n})).map((function(t){return new Us(t)})),i=t.append("g").attr("class","range-set"),a=(r=this)._ideo,i.selectAll("rect.range").data(o).enter().append("rect").attr("class","range").attr("x",(function(t){return a.convertBpToPx(r._model,t.start)})).attr("y",0).attr("width",(function(t){return a.convertBpToPx(r._model,t.length)})).attr("height",this._config.chrWidth).style("fill",(function(t){return t.getColor(e)})))}_getShapeData(){var t,n,e,r;for(n=0;n<this._model.bands.length;n++)if("q"===this._model.bands[n].name[0]){t=this._model.bands[n];break}return e=this._model.bands.length-1,r=this._model.bands[e].px.stop,{x1:0,x2:t?t.px.start:r,x3:r,w:this._config.chrWidth,b:this._config.chrWidth/this._bumpCoefficient}}_getPArmShape(){var t=this._getShapeData(),n=t.x2-t.b;return this.isFullyBanded()||"ancestors"in this._ideo.config?{class:"",path:"M"+t.b+",0 L"+n+",0 Q"+(t.x2+t.b)+","+t.w/2+","+n+","+t.w+" L"+t.b+","+t.w+" Q-"+t.b+","+t.w/2+","+t.b+",0"}:[{class:"",path:"M"+t.b+",0 L"+(n-2)+",0 L"+(n-2)+","+t.w+" L"+t.b+","+t.w+" Q-"+t.b+","+t.w/2+","+t.b+",0"},{class:"acen",path:"M"+n+",0 Q"+(t.x2+t.b)+","+t.w/2+","+n+","+t.w+" L"+n+","+t.w+" L"+(n-2)+","+t.w+" L"+(n-2)+",0"}]}_getQArmShape(){var t=this._getShapeData(),n=t.x3-t.b,e=t.x2+t.b;return this.isFullyBanded()||"ancestors"in this._ideo.config?{class:"",path:"M"+e+",0 L"+n+",0 Q"+(t.x3+t.b)+","+t.w/2+","+n+","+t.w+" L"+e+","+t.w+" Q"+(t.x2-t.b)+","+t.w/2+","+e+",0"}:[{path:"M"+e+",0 L"+n+",0 Q"+(t.x3+t.b)+","+t.w/2+","+n+","+t.w+" L"+e+","+t.w+" L"+e+",0"},{class:"acen",path:"M"+e+",0Q"+(t.x2-t.b)+","+t.w/2+","+e+","+t.w+" L"+e+","+t.w+"L"+(e+2)+","+t.w+"L"+(e+2)+",0"}]}isFullyBanded(){return this._model.bands&&(2!==this._model.bands.length||"q"===this._model.bands[0].name[0])}_renderBands(t,n,e,r,o){var i,a,s;a="p"===o?0:1,s="","ancestors"in(i=this)._ideo.config&&!i.isFullyBanded()&&(s=i._color.getArmColor(n,e,a)),t.selectAll("path.band."+o).data(r).enter().append("path").attr("id",(function(t){return i._model.id+"-"+t.name.replace(".","-")})).attr("class",(function(t){return"band "+o+"-band "+t.stain})).attr("d",(function(t){var n;return"M "+i._ideo.round(t.px.start)+", 0l "+(n=i._ideo.round(t.px.width))+" 0 l 0 "+i._config.chrWidth+" l -"+n+" 0 z"})).style("fill",s)}_renderArm(t,n,e,r){var o=this._model.bands.filter((function(t){return t.name[0]===r}));return this._renderBands(t,n,e,o,r),Boolean(o.length)}}class Qs extends Vs{constructor(t,n,e){super(t,n,e),this._class="MetacentricChromosome"}}class Js extends Vs{constructor(t,n,e){super(t,n,e),this._class="TelocentricPChromosome",this._pArmOffset=3}_addPArmShape(t){return t.concat(this._getPArmShape())}_getPArmShape(){var t=this._getShapeData();return t.o=this._pArmOffset,[{class:"acen",path:"M"+(t.x2+2)+",1L"+(t.x2+t.o+3.25)+",1 L"+(t.x2+t.o+3.25)+","+(t.w-1)+" L"+(t.x2+2)+","+(t.w-1)},{class:"gpos66",path:"M"+(t.x2-t.o+5)+",0L"+(t.x2-t.o+3)+",0 L"+(t.x2-t.o+3)+","+t.w+" L"+(t.x2-t.o+5)+","+t.w,strokeWidth:.5}]}_getQArmShape(){var t=this._getShapeData(),n=t.x3-t.b,e=this._pArmOffset+3;return{class:"",path:"M"+(t.x2+e)+",0 L"+n+",0 Q"+(t.x3+t.b)+","+t.w/2+","+n+","+t.w+" L"+(t.x2+e)+","+t.w}}}class Zs extends Vs{constructor(t,n,e){super(t,n,e),this._class="TelocentricQChromosome",this._qArmOffset=3}_getPArmShape(){var t=this._getShapeData(),n=t.x3-t.b,e=this._qArmOffset;return{class:"",path:"M"+(t.x2+e)+",0 L"+(n+e)+",0 L"+(n+e)+","+t.w+" L"+t.b+","+t.w+" Q-"+t.b+","+t.w/2+","+t.b+",0"}}_addQArmShape(t){return t.concat(this._getQArmShape())}_getQArmShape(){var t=this._getShapeData();return t.o=this._qArmOffset,[{class:"acen",path:"M"+(t.x2+2)+",1 L"+(t.x2+t.o+3.25)+",1 L"+(t.x2+t.o+3.25)+","+(t.w-1)+" L"+(t.x2+2)+","+(t.w-1)},{class:"gpos66",path:"M"+(t.x2+t.o+5)+",0 L"+(t.x2+t.o+3)+",0 L"+(t.x2+t.o+3)+","+t.w+" L"+(t.x2+t.o+5)+","+t.w,strokeWidth:.5}]}}function Ks(t,n,e,r){var o,i,a,s,c;s=Lo.select(this.selector+" defs"),c=Gs.getInstance(t),o=e*this.config.chrMargin,i=r.append("g").attr("id",t.id).attr("class","chromosome "+c.getCssClass()).attr("transform","translate(0, "+o+")"),a=Vs.getInstance(c,this.config,this).render(i,n,e),Lo.select("#"+t.id+"-chromosome-set-clippath").remove(),s.append("clipPath").attr("id",t.id+"-chromosome-set-clippath").selectAll("path").data(a).enter().append("path").attr("d",(function(t){return t.path})).attr("class",(function(t){return t.class}))}function tc(t){var n,e,r,o,i,a;if(n=t.chrIndex,o=this._layout.getChromosomeSetTranslate(n),a=this.selector+" #"+t.id+"-chromosome-set",Lo.selectAll(a+" g").remove(),0===(e=Lo.select(a)).nodes().length&&(e=Lo.select(this.selector).append("g").attr("class","chromosome-set").attr("transform",o).attr("id",t.id+"-chromosome-set")),"sex"in this.config&&2===this.config.ploidy&&this.sexChromosomes.index===n)this.drawSexChromosomes(e,n);else for(r=1,this.config.ploidy>1&&(r=this._ploidy.getChromosomesNumber(n)),i=0;i<r;i++)this.appendHomolog(t,n,i,e)}function nc(t){var n,e;this.config.taxid&&(n=t.id.split("-")[0].replace("chr",""),e=this.chromosomes[this.config.taxid][n].chrIndex,this._layout.rotate(e,e,t))}function ec(){var t,n,e,r,o,i,a;t=this.config,o=Lo.select(t.container+" svg#_ideogram"),e=Lo.select(t.container+" #_ideogramInnerWrap"),r=Lo.select(t.container+" #_ideogramMiddleWrap"),a=1===(i=t.ploidy)?i:1.12*i;let s=0;"annotationsLayout"in t&&(s=t.annotationHeight*t.numAnnotTracks),"vertical"===t.orientation&&"comparative"!==t.perspective&&"collinear"!==t.geometry&&(n=this.numChromosomes*(t.chrWidth+t.chrMargin+s),"heatmap-2d"!==t.annotationsLayout&&(n=Math.ceil(n*a/t.rows),"SmallLayout"===this._layout._class&&(n+=100),n+=35,r.style("height",this._layout.getHeight()+"px"),e.style("max-width",n+"px").style("overflow-x","scroll").style("position","absolute"),o.style("min-width",n-5+"px")))}function rc(t){var n=t._layout;Lo.selectAll(t.selector+" .chromosome-set").insert("text",":first-child").data(t.chromosomesArray).attr("class",n.getChromosomeLabelClass()).attr("transform",n.getChromosomeSetLabelTranslate()).attr("x",n.getChromosomeSetLabelXPosition()).attr("y",(function(t,e){return n.getChromosomeSetLabelYPosition(e)})).attr("text-anchor",n.getChromosomeSetLabelAnchor()).each((function(n,e){!function(t,n,e,r){var o=function(t,n,e){var r;return r=-1===t.name.indexOf(" ")?[t.name]:t.name.match(/^(.*)\s+([^\s]+)$/).slice(1).reverse(),"sex"in e.config&&2===e.config.ploidy&&n===e.sexChromosomes.index&&(r="male"===e.config.sex?["XY"]:["XX"]),r}(t,n,r);Lo.select(e).selectAll("tspan").data(o).enter().append("tspan").attr("dy",(function(t,n){return-1.2*n+"em"})).attr("x",r._layout.getChromosomeSetLabelXPosition()).attr("class",(function(t,n){var e=r.config.fullChromosomeLabels;return 1===n&&e?"italic":null})).text(String)}(n,e,this,t)}))}function oc(){rc(this),function(t){var n=t._layout;Lo.selectAll(t.selector+" .chromosome-set").each((function(e,r){Lo.select(this).selectAll(".chromosome").append("text").attr("class","chrLabel").attr("transform",n.getChromosomeSetLabelTranslate()).attr("x",(function(t,e){return n.getChromosomeLabelXPosition(e)})).attr("y",(function(t,e){return n.getChromosomeLabelYPosition(e)})).text((function(n,e){return t._ploidy.getAncestor(r,e)})).attr("text-anchor","middle")}))}(this)}function ic(t,n,e,r){var o;n-=1,o=function(t){var n,e,r;return void 0===t||!t.hasOwnProperty("x")||1===t.x&&1===t.y?(n=-8,e=-16,t={x:1,y:1},r=""):(r="scale("+t.x+","+t.y+")",n=-6,e=""===t?-16:-14),{x:n,y:e,scaleSvg:r,scale:t}}(r),"vertical"===e||""===e?function(t,n,e,r){var o,i,a,s=r.config;n=function(t,n){return(n.numAnnotTracks>1||""===n.orientation)&&(t-=1),t}(n,s),o=-4,!0===s.showBandLabels&&(o=s.chrMargin+s.chrWidth+26),i=s.chrMargin*n,s.numAnnotTracks>1==!1&&(i+=1),a=i+o,t.selectAll("text.chrLabel").attr("transform",e.scaleSvg).selectAll("tspan").attr("x",e.x).attr("y",a)}(t,n,o,this):function(t,n,e,r){var o,i,a,s=r.config;o=-s.chrWidth-2,!0===s.showBandLabels&&(o=s.chrMargin+8),i=s.annotTracksHeight,"overlay"!==s.annotationsLayout&&(i*=2),a=3-(s.chrMargin*n+o)+i,a/=e.scale.x,t.selectAll("text.chrLabel").attr("transform","rotate(-90)"+e.scaleSvg).selectAll("tspan").attr("x",a).attr("y",e.y)}(t,n,o,this)}async function ac(t){const n=await fetch("https://mygene.info/v3/query"+t);return await n.json()}function sc(t,n,e="red"){let r=null;r=Array.isArray(t.genomic_pos)?t.genomic_pos.filter(t=>t.chr in n.chromosomes[n.config.taxid])[0]:t.genomic_pos;return{name:t.symbol,chr:r.chr,start:r.start,stop:r.end,id:r.ensemblgene,color:e}}async function cc(t){this.annotDescriptions={};const n=this.selector+" .annot";document.querySelectorAll(n).forEach(t=>t.remove()),this.startHideAnnotTooltipTimeout(),document.querySelectorAll(".chromosome").forEach(t=>{t.style.cursor=""});const e=`float: left; position: relative; top: -${this.config.chrHeight+30}px; left: ${Array.from(document.querySelectorAll(".chromosome-set")).slice(-1)[0].getBoundingClientRect().right}px;`,r=`?q=symbol:${t}&species=${this.config.taxid}&fields=symbol,genomic_pos,name`,o=(await ac(r)).hits[0];this.annotDescriptions[o.symbol]=o.name;let i=[];const a=sc(o,this);i.push(a);const s=await async function(t,n){const e={},r={},o=n.config.organism.replace(/-/g," "),i="https://webservice.wikipathways.org/findInteractions"+`?query=${t.name}&format=json`,a=await fetch(i);return(await a.json()).result.forEach(n=>{if(n.species.toLowerCase()===o){const o=n.fields.right.values,i=n.fields.left.values,a=o.concat(i),s=n.name,c=n.id;a.forEach(n=>{const o=s+c;if(function(t,n){return""!==t&&!t.includes(" ")&&!t.includes("/")&&t.toLowerCase()!==n.name.toLowerCase()}(n,t)&&!(o in r)){r[o]=1;const t={name:s,pathwayId:c};n in e?e[n].push(t):e[n]=[t]}})}}),e}(a,this),c=await async function(t,n){const e=[],r=Object.keys(t);if(0===r.length)return e;const o=`?q=${r.map(t=>"symbol:"+t.trim()).join(" OR ")}&species=${n.config.taxid}&fields=symbol,genomic_pos,name`;return(await ac(o)).hits.forEach(r=>{if("genomic_pos"in r==!1)return;const o=sc(r,n,"purple");e.push(o);const i=function(t,n){let e=t.name;if(void 0!==n){const t="https://www.wikipathways.org/index.php/Pathway:",r=n.map(n=>`<a href="${`${t}${n.pathwayId}`}" target="_blank">${n.name}</a>`).join("<br/>");let o="pathway";n.length>1&&(o+="s"),e+=`\n      <br/><br/>\n      Interacts in ${o}:<br/>\n      ${r}`}return e}(r,t[r.symbol]);n.annotDescriptions[r.symbol]=i}),e}(s,this);i=i.concat(c),await async function(t,n,e){const r=e.config.taxid,o=e.config.organism.replace(/[ -]/g,"_"),i="&format=condensed&type=paralogues&target_taxon="+r;let a=`/homology/id/${t.id}?${i}`;const s=await Ideogram.fetchEnsembl(a);a="/lookup/id/"+o;const c={ids:s.data[0].homologies.map(t=>t.id),species:o,object_type:"gene"},l=await Ideogram.fetchEnsembl(a,c,"POST");return Object.entries(l).map((t,r)=>{const o=t[1];if("display_name"in o==!1)return;const i={name:o.display_name,chr:o.seq_region_name,start:o.start,stop:o.end,id:o.id,color:"pink"};n.unshift(i),e.annotDescriptions[i.name]=o.description}),n}(a,i,this),i.sort((t,n)=>n.name.length-t.name.length),this.drawAnnots(i),document.querySelector("#_ideogramLegend").style=e}function lc(t){const n=this.getScientificName(this.config.taxid),e="https://ncbi.nlm.nih.gov/gene/?term="+`(${t.name}[gene])+AND+(${n}[orgn])`,r=this.annotDescriptions[t.name].split(" [")[0];return t.displayName=`<a target="_blank" href="${e}">${t.name}</a>\n    <br/>\n    ${r}\n    <br/>`,t}const uc=[{name:"<b>Click gene to search</b>",rows:[{name:"Interacting gene",color:"purple",shape:"triangle"},{name:"Paralogous gene",color:"pink",shape:"triangle"},{name:"Searched gene",color:"red",shape:"triangle"}]}];class 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get version(){return"1.22.0"}static get d3(){return Lo}static async fetchEnsembl(t,n=null,e="GET"){const r={method:e,headers:{"Content-Type":"application/json"}};null!==n&&(r.body=JSON.stringify(n));const o=await fetch("https://rest.ensembl.org"+t,r);return await o.json()}static sortChromosomes(t,n){var e="nuclear"===t.type,r="nuclear"===n.type,o="chloroplast"===t.type,i="chloroplast"===n.type,a="mitochondrion"===t.type,s="mitochondrion"===n.type,c="apicoplast"===t.type,l="apicoplast"===n.type;return e&&r?t.name.localeCompare(n.name,"en",{numeric:!0}):!e&&r||a&&i?1:o&&s?-1:c||a||o||!(s||i||l)?void 0:-1}static initRelatedGenes(t){return function(t){return Object.assign(t,{showFullyBanded:!1,rotatable:!1,legend:uc,onWillShowAnnotTooltip:lc}),new Ideogram(t)}(t)}}window.Ideogram=hc;n.default=hc}})}));
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diff --git a/dist/js/ideogram.min.js.map b/dist/js/ideogram.min.js.map
index 7377ae10..62bfc354 100644
--- a/dist/js/ideogram.min.js.map
+++ b/dist/js/ideogram.min.js.map
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\t\tmodule.l = true;\n\n \t\t// Return the exports of the module\n \t\treturn module.exports;\n \t}\n\n\n \t// expose the modules object (__webpack_modules__)\n \t__webpack_require__.m = modules;\n\n \t// expose the module cache\n \t__webpack_require__.c = installedModules;\n\n \t// define getter function for harmony exports\n \t__webpack_require__.d = function(exports, name, getter) {\n \t\tif(!__webpack_require__.o(exports, name)) {\n \t\t\tObject.defineProperty(exports, name, { enumerable: true, get: getter });\n \t\t}\n \t};\n\n \t// define __esModule on exports\n \t__webpack_require__.r = function(exports) {\n \t\tif(typeof Symbol !== 'undefined' && Symbol.toStringTag) {\n \t\t\tObject.defineProperty(exports, Symbol.toStringTag, { value: 'Module' });\n \t\t}\n \t\tObject.defineProperty(exports, '__esModule', { value: true });\n \t};\n\n \t// create a fake namespace object\n \t// mode & 1: value is a module id, require it\n \t// mode & 2: merge all properties of value into the ns\n \t// mode & 4: return value when already ns object\n \t// mode & 8|1: behave like require\n \t__webpack_require__.t = function(value, mode) {\n \t\tif(mode & 1) value = __webpack_require__(value);\n \t\tif(mode & 8) return value;\n \t\tif((mode & 4) && typeof value === 'object' && value && value.__esModule) return value;\n \t\tvar ns = Object.create(null);\n \t\t__webpack_require__.r(ns);\n \t\tObject.defineProperty(ns, 'default', { enumerable: true, value: value });\n \t\tif(mode & 2 && typeof value != 'string') for(var key in value) __webpack_require__.d(ns, key, function(key) { return value[key]; }.bind(null, key));\n \t\treturn ns;\n \t};\n\n \t// getDefaultExport function for compatibility with non-harmony modules\n \t__webpack_require__.n = function(module) {\n \t\tvar getter = module && module.__esModule ?\n \t\t\tfunction getDefault() { return module['default']; } :\n \t\t\tfunction getModuleExports() { return module; };\n \t\t__webpack_require__.d(getter, 'a', getter);\n \t\treturn getter;\n \t};\n\n \t// Object.prototype.hasOwnProperty.call\n \t__webpack_require__.o = function(object, property) { return Object.prototype.hasOwnProperty.call(object, property); };\n\n \t// __webpack_public_path__\n \t__webpack_require__.p = \"/dist/js\";\n\n\n \t// Load entry module and return exports\n \treturn __webpack_require__(__webpack_require__.s = 5);\n","function none() {}\n\nexport default function(selector) {\n  return selector == null ? none : function() {\n    return this.querySelector(selector);\n  };\n}\n","function empty() {\n  return [];\n}\n\nexport default function(selector) {\n  return selector == null ? empty : function() {\n    return this.querySelectorAll(selector);\n  };\n}\n","export default function(selector) {\n  return function() {\n    return this.matches(selector);\n  };\n}\n","export default function(update) {\n  return new Array(update.length);\n}\n","import sparse from \"./sparse\";\nimport {Selection} from \"./index\";\n\nexport default function() {\n  return new Selection(this._enter || this._groups.map(sparse), this._parents);\n}\n\nexport function EnterNode(parent, datum) {\n  this.ownerDocument = parent.ownerDocument;\n  this.namespaceURI = parent.namespaceURI;\n  this._next = null;\n  this._parent = parent;\n  this.__data__ = datum;\n}\n\nEnterNode.prototype = {\n  constructor: EnterNode,\n  appendChild: function(child) { return this._parent.insertBefore(child, this._next); },\n  insertBefore: function(child, next) { return this._parent.insertBefore(child, next); },\n  querySelector: function(selector) { return this._parent.querySelector(selector); },\n  querySelectorAll: function(selector) { return this._parent.querySelectorAll(selector); }\n};\n","import {Selection} from \"./index\";\nimport {EnterNode} from \"./enter\";\nimport constant from \"../constant\";\n\nvar keyPrefix = \"$\"; // Protect against keys like “__proto__”.\n\nfunction bindIndex(parent, group, enter, update, exit, data) {\n  var i = 0,\n      node,\n      groupLength = group.length,\n      dataLength = data.length;\n\n  // Put any non-null nodes that fit into update.\n  // Put any null nodes into enter.\n  // Put any remaining data into enter.\n  for (; i < dataLength; ++i) {\n    if (node = group[i]) {\n      node.__data__ = data[i];\n      update[i] = node;\n    } else {\n      enter[i] = new EnterNode(parent, data[i]);\n    }\n  }\n\n  // Put any non-null nodes that don’t fit into exit.\n  for (; i < groupLength; ++i) {\n    if (node = group[i]) {\n      exit[i] = node;\n    }\n  }\n}\n\nfunction bindKey(parent, group, enter, update, exit, data, key) {\n  var i,\n      node,\n      nodeByKeyValue = {},\n      groupLength = group.length,\n      dataLength = data.length,\n      keyValues = new Array(groupLength),\n      keyValue;\n\n  // Compute the key for each node.\n  // If multiple nodes have the same key, the duplicates are added to exit.\n  for (i = 0; i < groupLength; ++i) {\n    if (node = group[i]) {\n      keyValues[i] = keyValue = keyPrefix + key.call(node, node.__data__, i, group);\n      if (keyValue in nodeByKeyValue) {\n        exit[i] = node;\n      } else {\n        nodeByKeyValue[keyValue] = node;\n      }\n    }\n  }\n\n  // Compute the key for each datum.\n  // If there a node associated with this key, join and add it to update.\n  // If there is not (or the key is a duplicate), add it to enter.\n  for (i = 0; i < dataLength; ++i) {\n    keyValue = keyPrefix + key.call(parent, data[i], i, data);\n    if (node = nodeByKeyValue[keyValue]) {\n      update[i] = node;\n      node.__data__ = data[i];\n      nodeByKeyValue[keyValue] = null;\n    } else {\n      enter[i] = new EnterNode(parent, data[i]);\n    }\n  }\n\n  // Add any remaining nodes that were not bound to data to exit.\n  for (i = 0; i < groupLength; ++i) {\n    if ((node = group[i]) && (nodeByKeyValue[keyValues[i]] === node)) {\n      exit[i] = node;\n    }\n  }\n}\n\nexport default function(value, key) {\n  if (!value) {\n    data = new Array(this.size()), j = -1;\n    this.each(function(d) { data[++j] = d; });\n    return data;\n  }\n\n  var bind = key ? bindKey : bindIndex,\n      parents = this._parents,\n      groups = this._groups;\n\n  if (typeof value !== \"function\") value = constant(value);\n\n  for (var m = groups.length, update = new Array(m), enter = new Array(m), exit = new Array(m), j = 0; j < m; ++j) {\n    var parent = parents[j],\n        group = groups[j],\n        groupLength = group.length,\n        data = value.call(parent, parent && parent.__data__, j, parents),\n        dataLength = data.length,\n        enterGroup = enter[j] = new Array(dataLength),\n        updateGroup = update[j] = new Array(dataLength),\n        exitGroup = exit[j] = new Array(groupLength);\n\n    bind(parent, group, enterGroup, updateGroup, exitGroup, data, key);\n\n    // Now connect the enter nodes to their following update node, such that\n    // appendChild can insert the materialized enter node before this node,\n    // rather than at the end of the parent node.\n    for (var i0 = 0, i1 = 0, previous, next; i0 < dataLength; ++i0) {\n      if (previous = enterGroup[i0]) {\n        if (i0 >= i1) i1 = i0 + 1;\n        while (!(next = updateGroup[i1]) && ++i1 < dataLength);\n        previous._next = next || null;\n      }\n    }\n  }\n\n  update = new Selection(update, parents);\n  update._enter = enter;\n  update._exit = exit;\n  return update;\n}\n","import {Selection} from \"./index\";\n\nexport default function(compare) {\n  if (!compare) compare = ascending;\n\n  function compareNode(a, b) {\n    return a && b ? compare(a.__data__, b.__data__) : !a - !b;\n  }\n\n  for (var groups = this._groups, m = groups.length, sortgroups = new Array(m), j = 0; j < m; ++j) {\n    for (var group = groups[j], n = group.length, sortgroup = sortgroups[j] = new Array(n), node, i = 0; i < n; ++i) {\n      if (node = group[i]) {\n        sortgroup[i] = node;\n      }\n    }\n    sortgroup.sort(compareNode);\n  }\n\n  return new Selection(sortgroups, this._parents).order();\n}\n\nfunction ascending(a, b) {\n  return a < b ? -1 : a > b ? 1 : a >= b ? 0 : NaN;\n}\n","export default function() {\n  var callback = arguments[0];\n  arguments[0] = this;\n  callback.apply(null, arguments);\n  return this;\n}\n","export var xhtml = \"http://www.w3.org/1999/xhtml\";\n\nexport default {\n  svg: \"http://www.w3.org/2000/svg\",\n  xhtml: xhtml,\n  xlink: \"http://www.w3.org/1999/xlink\",\n  xml: \"http://www.w3.org/XML/1998/namespace\",\n  xmlns: \"http://www.w3.org/2000/xmlns/\"\n};\n","import namespaces from \"./namespaces\";\n\nexport default function(name) {\n  var prefix = name += \"\", i = prefix.indexOf(\":\");\n  if (i >= 0 && (prefix = name.slice(0, i)) !== \"xmlns\") name = name.slice(i + 1);\n  return namespaces.hasOwnProperty(prefix) ? {space: namespaces[prefix], local: name} : name;\n}\n","import namespace from \"../namespace\";\n\nfunction attrRemove(name) {\n  return function() {\n    this.removeAttribute(name);\n  };\n}\n\nfunction attrRemoveNS(fullname) {\n  return function() {\n    this.removeAttributeNS(fullname.space, fullname.local);\n  };\n}\n\nfunction attrConstant(name, value) {\n  return function() {\n    this.setAttribute(name, value);\n  };\n}\n\nfunction attrConstantNS(fullname, value) {\n  return function() {\n    this.setAttributeNS(fullname.space, fullname.local, value);\n  };\n}\n\nfunction attrFunction(name, value) {\n  return function() {\n    var v = value.apply(this, arguments);\n    if (v == null) this.removeAttribute(name);\n    else this.setAttribute(name, v);\n  };\n}\n\nfunction attrFunctionNS(fullname, value) {\n  return function() {\n    var v = value.apply(this, arguments);\n    if (v == null) this.removeAttributeNS(fullname.space, fullname.local);\n    else this.setAttributeNS(fullname.space, fullname.local, v);\n  };\n}\n\nexport default function(name, value) {\n  var fullname = namespace(name);\n\n  if (arguments.length < 2) {\n    var node = this.node();\n    return fullname.local\n        ? node.getAttributeNS(fullname.space, fullname.local)\n        : node.getAttribute(fullname);\n  }\n\n  return this.each((value == null\n      ? (fullname.local ? attrRemoveNS : attrRemove) : (typeof value === \"function\"\n      ? (fullname.local ? attrFunctionNS : attrFunction)\n      : (fullname.local ? attrConstantNS : attrConstant)))(fullname, value));\n}\n","export default function(node) {\n  return (node.ownerDocument && node.ownerDocument.defaultView) // node is a Node\n      || (node.document && node) // node is a Window\n      || node.defaultView; // node is a Document\n}\n","import defaultView from \"../window\";\n\nfunction styleRemove(name) {\n  return function() {\n    this.style.removeProperty(name);\n  };\n}\n\nfunction styleConstant(name, value, priority) {\n  return function() {\n    this.style.setProperty(name, value, priority);\n  };\n}\n\nfunction styleFunction(name, value, priority) {\n  return function() {\n    var v = value.apply(this, arguments);\n    if (v == null) this.style.removeProperty(name);\n    else this.style.setProperty(name, v, priority);\n  };\n}\n\nexport default function(name, value, priority) {\n  return arguments.length > 1\n      ? this.each((value == null\n            ? styleRemove : typeof value === \"function\"\n            ? styleFunction\n            : styleConstant)(name, value, priority == null ? \"\" : priority))\n      : styleValue(this.node(), name);\n}\n\nexport function styleValue(node, name) {\n  return node.style.getPropertyValue(name)\n      || defaultView(node).getComputedStyle(node, null).getPropertyValue(name);\n}\n","function propertyRemove(name) {\n  return function() {\n    delete this[name];\n  };\n}\n\nfunction propertyConstant(name, value) {\n  return function() {\n    this[name] = value;\n  };\n}\n\nfunction propertyFunction(name, value) {\n  return function() {\n    var v = value.apply(this, arguments);\n    if (v == null) delete this[name];\n    else this[name] = v;\n  };\n}\n\nexport default function(name, value) {\n  return arguments.length > 1\n      ? this.each((value == null\n          ? propertyRemove : typeof value === \"function\"\n          ? propertyFunction\n          : propertyConstant)(name, value))\n      : this.node()[name];\n}\n","function classArray(string) {\n  return string.trim().split(/^|\\s+/);\n}\n\nfunction classList(node) {\n  return node.classList || new ClassList(node);\n}\n\nfunction ClassList(node) {\n  this._node = node;\n  this._names = classArray(node.getAttribute(\"class\") || \"\");\n}\n\nClassList.prototype = {\n  add: function(name) {\n    var i = this._names.indexOf(name);\n    if (i < 0) {\n      this._names.push(name);\n      this._node.setAttribute(\"class\", this._names.join(\" \"));\n    }\n  },\n  remove: function(name) {\n    var i = this._names.indexOf(name);\n    if (i >= 0) {\n      this._names.splice(i, 1);\n      this._node.setAttribute(\"class\", this._names.join(\" \"));\n    }\n  },\n  contains: function(name) {\n    return this._names.indexOf(name) >= 0;\n  }\n};\n\nfunction classedAdd(node, names) {\n  var list = classList(node), i = -1, n = names.length;\n  while (++i < n) list.add(names[i]);\n}\n\nfunction classedRemove(node, names) {\n  var list = classList(node), i = -1, n = names.length;\n  while (++i < n) list.remove(names[i]);\n}\n\nfunction classedTrue(names) {\n  return function() {\n    classedAdd(this, names);\n  };\n}\n\nfunction classedFalse(names) {\n  return function() {\n    classedRemove(this, names);\n  };\n}\n\nfunction classedFunction(names, value) {\n  return function() {\n    (value.apply(this, arguments) ? classedAdd : classedRemove)(this, names);\n  };\n}\n\nexport default function(name, value) {\n  var names = classArray(name + \"\");\n\n  if (arguments.length < 2) {\n    var list = classList(this.node()), i = -1, n = names.length;\n    while (++i < n) if (!list.contains(names[i])) return false;\n    return true;\n  }\n\n  return this.each((typeof value === \"function\"\n      ? classedFunction : value\n      ? classedTrue\n      : classedFalse)(names, value));\n}\n","function textRemove() {\n  this.textContent = \"\";\n}\n\nfunction textConstant(value) {\n  return function() {\n    this.textContent = value;\n  };\n}\n\nfunction textFunction(value) {\n  return function() {\n    var v = value.apply(this, arguments);\n    this.textContent = v == null ? \"\" : v;\n  };\n}\n\nexport default function(value) {\n  return arguments.length\n      ? this.each(value == null\n          ? textRemove : (typeof value === \"function\"\n          ? textFunction\n          : textConstant)(value))\n      : this.node().textContent;\n}\n","function htmlRemove() {\n  this.innerHTML = \"\";\n}\n\nfunction htmlConstant(value) {\n  return function() {\n    this.innerHTML = value;\n  };\n}\n\nfunction htmlFunction(value) {\n  return function() {\n    var v = value.apply(this, arguments);\n    this.innerHTML = v == null ? \"\" : v;\n  };\n}\n\nexport default function(value) {\n  return arguments.length\n      ? this.each(value == null\n          ? htmlRemove : (typeof value === \"function\"\n          ? htmlFunction\n          : htmlConstant)(value))\n      : this.node().innerHTML;\n}\n","function raise() {\n  if (this.nextSibling) this.parentNode.appendChild(this);\n}\n\nexport default function() {\n  return this.each(raise);\n}\n","function lower() {\n  if (this.previousSibling) this.parentNode.insertBefore(this, this.parentNode.firstChild);\n}\n\nexport default function() {\n  return this.each(lower);\n}\n","import namespace from \"./namespace\";\nimport {xhtml} from \"./namespaces\";\n\nfunction creatorInherit(name) {\n  return function() {\n    var document = this.ownerDocument,\n        uri = this.namespaceURI;\n    return uri === xhtml && document.documentElement.namespaceURI === xhtml\n        ? document.createElement(name)\n        : document.createElementNS(uri, name);\n  };\n}\n\nfunction creatorFixed(fullname) {\n  return function() {\n    return this.ownerDocument.createElementNS(fullname.space, fullname.local);\n  };\n}\n\nexport default function(name) {\n  var fullname = namespace(name);\n  return (fullname.local\n      ? creatorFixed\n      : creatorInherit)(fullname);\n}\n","import creator from \"../creator\";\nimport selector from \"../selector\";\n\nfunction constantNull() {\n  return null;\n}\n\nexport default function(name, before) {\n  var create = typeof name === \"function\" ? name : creator(name),\n      select = before == null ? constantNull : typeof before === \"function\" ? before : selector(before);\n  return this.select(function() {\n    return this.insertBefore(create.apply(this, arguments), select.apply(this, arguments) || null);\n  });\n}\n","function remove() {\n  var parent = this.parentNode;\n  if (parent) parent.removeChild(this);\n}\n\nexport default function() {\n  return this.each(remove);\n}\n","function selection_cloneShallow() {\n  var clone = this.cloneNode(false), parent = this.parentNode;\n  return parent ? parent.insertBefore(clone, this.nextSibling) : clone;\n}\n\nfunction selection_cloneDeep() {\n  var clone = this.cloneNode(true), parent = this.parentNode;\n  return parent ? parent.insertBefore(clone, this.nextSibling) : clone;\n}\n\nexport default function(deep) {\n  return this.select(deep ? selection_cloneDeep : selection_cloneShallow);\n}\n","var filterEvents = {};\n\nexport var event = null;\n\nif (typeof document !== \"undefined\") {\n  var element = document.documentElement;\n  if (!(\"onmouseenter\" in element)) {\n    filterEvents = {mouseenter: \"mouseover\", mouseleave: \"mouseout\"};\n  }\n}\n\nfunction filterContextListener(listener, index, group) {\n  listener = contextListener(listener, index, group);\n  return function(event) {\n    var related = event.relatedTarget;\n    if (!related || (related !== this && !(related.compareDocumentPosition(this) & 8))) {\n      listener.call(this, event);\n    }\n  };\n}\n\nfunction contextListener(listener, index, group) {\n  return function(event1) {\n    var event0 = event; // Events can be reentrant (e.g., focus).\n    event = event1;\n    try {\n      listener.call(this, this.__data__, index, group);\n    } finally {\n      event = event0;\n    }\n  };\n}\n\nfunction parseTypenames(typenames) {\n  return typenames.trim().split(/^|\\s+/).map(function(t) {\n    var name = \"\", i = t.indexOf(\".\");\n    if (i >= 0) name = t.slice(i + 1), t = t.slice(0, i);\n    return {type: t, name: name};\n  });\n}\n\nfunction onRemove(typename) {\n  return function() {\n    var on = this.__on;\n    if (!on) return;\n    for (var j = 0, i = -1, m = on.length, o; j < m; ++j) {\n      if (o = on[j], (!typename.type || o.type === typename.type) && o.name === typename.name) {\n        this.removeEventListener(o.type, o.listener, o.capture);\n      } else {\n        on[++i] = o;\n      }\n    }\n    if (++i) on.length = i;\n    else delete this.__on;\n  };\n}\n\nfunction onAdd(typename, value, capture) {\n  var wrap = filterEvents.hasOwnProperty(typename.type) ? filterContextListener : contextListener;\n  return function(d, i, group) {\n    var on = this.__on, o, listener = wrap(value, i, group);\n    if (on) for (var j = 0, m = on.length; j < m; ++j) {\n      if ((o = on[j]).type === typename.type && o.name === typename.name) {\n        this.removeEventListener(o.type, o.listener, o.capture);\n        this.addEventListener(o.type, o.listener = listener, o.capture = capture);\n        o.value = value;\n        return;\n      }\n    }\n    this.addEventListener(typename.type, listener, capture);\n    o = {type: typename.type, name: typename.name, value: value, listener: listener, capture: capture};\n    if (!on) this.__on = [o];\n    else on.push(o);\n  };\n}\n\nexport default function(typename, value, capture) {\n  var typenames = parseTypenames(typename + \"\"), i, n = typenames.length, t;\n\n  if (arguments.length < 2) {\n    var on = this.node().__on;\n    if (on) for (var j = 0, m = on.length, o; j < m; ++j) {\n      for (i = 0, o = on[j]; i < n; ++i) {\n        if ((t = typenames[i]).type === o.type && t.name === o.name) {\n          return o.value;\n        }\n      }\n    }\n    return;\n  }\n\n  on = value ? onAdd : onRemove;\n  if (capture == null) capture = false;\n  for (i = 0; i < n; ++i) this.each(on(typenames[i], value, capture));\n  return this;\n}\n\nexport function customEvent(event1, listener, that, args) {\n  var event0 = event;\n  event1.sourceEvent = event;\n  event = event1;\n  try {\n    return listener.apply(that, args);\n  } finally {\n    event = event0;\n  }\n}\n","import defaultView from \"../window\";\n\nfunction dispatchEvent(node, type, params) {\n  var window = defaultView(node),\n      event = window.CustomEvent;\n\n  if (typeof event === \"function\") {\n    event = new event(type, params);\n  } else {\n    event = window.document.createEvent(\"Event\");\n    if (params) event.initEvent(type, params.bubbles, params.cancelable), event.detail = params.detail;\n    else event.initEvent(type, false, false);\n  }\n\n  node.dispatchEvent(event);\n}\n\nfunction dispatchConstant(type, params) {\n  return function() {\n    return dispatchEvent(this, type, params);\n  };\n}\n\nfunction dispatchFunction(type, params) {\n  return function() {\n    return dispatchEvent(this, type, params.apply(this, arguments));\n  };\n}\n\nexport default function(type, params) {\n  return this.each((typeof params === \"function\"\n      ? dispatchFunction\n      : dispatchConstant)(type, params));\n}\n","import selection_select from \"./select\";\nimport selection_selectAll from \"./selectAll\";\nimport selection_filter from \"./filter\";\nimport selection_data from \"./data\";\nimport selection_enter from \"./enter\";\nimport selection_exit from \"./exit\";\nimport selection_join from \"./join\";\nimport selection_merge from \"./merge\";\nimport selection_order from \"./order\";\nimport selection_sort from \"./sort\";\nimport selection_call from \"./call\";\nimport selection_nodes from \"./nodes\";\nimport selection_node from \"./node\";\nimport selection_size from \"./size\";\nimport selection_empty from \"./empty\";\nimport selection_each from \"./each\";\nimport selection_attr from \"./attr\";\nimport selection_style from \"./style\";\nimport selection_property from \"./property\";\nimport selection_classed from \"./classed\";\nimport selection_text from \"./text\";\nimport selection_html from \"./html\";\nimport selection_raise from \"./raise\";\nimport selection_lower from \"./lower\";\nimport selection_append from \"./append\";\nimport selection_insert from \"./insert\";\nimport selection_remove from \"./remove\";\nimport selection_clone from \"./clone\";\nimport selection_datum from \"./datum\";\nimport selection_on from \"./on\";\nimport selection_dispatch from \"./dispatch\";\n\nexport var root = [null];\n\nexport function Selection(groups, parents) {\n  this._groups = groups;\n  this._parents = parents;\n}\n\nfunction selection() {\n  return new Selection([[document.documentElement]], root);\n}\n\nSelection.prototype = selection.prototype = {\n  constructor: Selection,\n  select: selection_select,\n  selectAll: selection_selectAll,\n  filter: selection_filter,\n  data: selection_data,\n  enter: selection_enter,\n  exit: selection_exit,\n  join: selection_join,\n  merge: selection_merge,\n  order: selection_order,\n  sort: selection_sort,\n  call: selection_call,\n  nodes: selection_nodes,\n  node: selection_node,\n  size: selection_size,\n  empty: selection_empty,\n  each: selection_each,\n  attr: selection_attr,\n  style: selection_style,\n  property: selection_property,\n  classed: selection_classed,\n  text: selection_text,\n  html: selection_html,\n  raise: selection_raise,\n  lower: selection_lower,\n  append: selection_append,\n  insert: selection_insert,\n  remove: selection_remove,\n  clone: selection_clone,\n  datum: selection_datum,\n  on: selection_on,\n  dispatch: selection_dispatch\n};\n\nexport default selection;\n","import {Selection} from \"./index\";\nimport selector from \"../selector\";\n\nexport default function(select) {\n  if (typeof select !== \"function\") select = selector(select);\n\n  for (var groups = this._groups, m = groups.length, subgroups = new Array(m), j = 0; j < m; ++j) {\n    for (var group = groups[j], n = group.length, subgroup = subgroups[j] = new Array(n), node, subnode, i = 0; i < n; ++i) {\n      if ((node = group[i]) && (subnode = select.call(node, node.__data__, i, group))) {\n        if (\"__data__\" in node) subnode.__data__ = node.__data__;\n        subgroup[i] = subnode;\n      }\n    }\n  }\n\n  return new Selection(subgroups, this._parents);\n}\n","import {Selection} from \"./index\";\nimport selectorAll from \"../selectorAll\";\n\nexport default function(select) {\n  if (typeof select !== \"function\") select = selectorAll(select);\n\n  for (var groups = this._groups, m = groups.length, subgroups = [], parents = [], j = 0; j < m; ++j) {\n    for (var group = groups[j], n = group.length, node, i = 0; i < n; ++i) {\n      if (node = group[i]) {\n        subgroups.push(select.call(node, node.__data__, i, group));\n        parents.push(node);\n      }\n    }\n  }\n\n  return new Selection(subgroups, parents);\n}\n","import {Selection} from \"./index\";\nimport matcher from \"../matcher\";\n\nexport default function(match) {\n  if (typeof match !== \"function\") match = matcher(match);\n\n  for (var groups = this._groups, m = groups.length, subgroups = new Array(m), j = 0; j < m; ++j) {\n    for (var group = groups[j], n = group.length, subgroup = subgroups[j] = [], node, i = 0; i < n; ++i) {\n      if ((node = group[i]) && match.call(node, node.__data__, i, group)) {\n        subgroup.push(node);\n      }\n    }\n  }\n\n  return new Selection(subgroups, this._parents);\n}\n","export default function(x) {\n  return function() {\n    return x;\n  };\n}\n","import sparse from \"./sparse\";\nimport {Selection} from \"./index\";\n\nexport default function() {\n  return new Selection(this._exit || this._groups.map(sparse), this._parents);\n}\n","export default function(onenter, onupdate, onexit) {\n  var enter = this.enter(), update = this, exit = this.exit();\n  enter = typeof onenter === \"function\" ? onenter(enter) : enter.append(onenter + \"\");\n  if (onupdate != null) update = onupdate(update);\n  if (onexit == null) exit.remove(); else onexit(exit);\n  return enter && update ? enter.merge(update).order() : update;\n}\n","import {Selection} from \"./index\";\n\nexport default function(selection) {\n\n  for (var groups0 = this._groups, groups1 = selection._groups, m0 = groups0.length, m1 = groups1.length, m = Math.min(m0, m1), merges = new Array(m0), j = 0; j < m; ++j) {\n    for (var group0 = groups0[j], group1 = groups1[j], n = group0.length, merge = merges[j] = new Array(n), node, i = 0; i < n; ++i) {\n      if (node = group0[i] || group1[i]) {\n        merge[i] = node;\n      }\n    }\n  }\n\n  for (; j < m0; ++j) {\n    merges[j] = groups0[j];\n  }\n\n  return new Selection(merges, this._parents);\n}\n","export default function() {\n\n  for (var groups = this._groups, j = -1, m = groups.length; ++j < m;) {\n    for (var group = groups[j], i = group.length - 1, next = group[i], node; --i >= 0;) {\n      if (node = group[i]) {\n        if (next && node.compareDocumentPosition(next) ^ 4) next.parentNode.insertBefore(node, next);\n        next = node;\n      }\n    }\n  }\n\n  return this;\n}\n","export default function() {\n  var nodes = new Array(this.size()), i = -1;\n  this.each(function() { nodes[++i] = this; });\n  return nodes;\n}\n","export default function() {\n\n  for (var groups = this._groups, j = 0, m = groups.length; j < m; ++j) {\n    for (var group = groups[j], i = 0, n = group.length; i < n; ++i) {\n      var node = group[i];\n      if (node) return node;\n    }\n  }\n\n  return null;\n}\n","export default function() {\n  var size = 0;\n  this.each(function() { ++size; });\n  return size;\n}\n","export default function() {\n  return !this.node();\n}\n","export default function(callback) {\n\n  for (var groups = this._groups, j = 0, m = groups.length; j < m; ++j) {\n    for (var group = groups[j], i = 0, n = group.length, node; i < n; ++i) {\n      if (node = group[i]) callback.call(node, node.__data__, i, group);\n    }\n  }\n\n  return this;\n}\n","import creator from \"../creator\";\n\nexport default function(name) {\n  var create = typeof name === \"function\" ? name : creator(name);\n  return this.select(function() {\n    return this.appendChild(create.apply(this, arguments));\n  });\n}\n","export default function(value) {\n  return arguments.length\n      ? this.property(\"__data__\", value)\n      : this.node().__data__;\n}\n","import {Selection, root} from \"./selection/index\";\n\nexport default function(selector) {\n  return typeof selector === \"string\"\n      ? new Selection([[document.querySelector(selector)]], [document.documentElement])\n      : new Selection([[selector]], root);\n}\n","function responseBlob(response) {\n  if (!response.ok) throw new Error(response.status + \" \" + response.statusText);\n  return response.blob();\n}\n\nexport default function(input, init) {\n  return fetch(input, init).then(responseBlob);\n}\n","function responseArrayBuffer(response) {\n  if (!response.ok) throw new Error(response.status + \" \" + response.statusText);\n  return response.arrayBuffer();\n}\n\nexport default function(input, init) {\n  return fetch(input, init).then(responseArrayBuffer);\n}\n","var EOL = {},\n    EOF = {},\n    QUOTE = 34,\n    NEWLINE = 10,\n    RETURN = 13;\n\nfunction objectConverter(columns) {\n  return new Function(\"d\", \"return {\" + columns.map(function(name, i) {\n    return JSON.stringify(name) + \": d[\" + i + \"] || \\\"\\\"\";\n  }).join(\",\") + \"}\");\n}\n\nfunction customConverter(columns, f) {\n  var object = objectConverter(columns);\n  return function(row, i) {\n    return f(object(row), i, columns);\n  };\n}\n\n// Compute unique columns in order of discovery.\nfunction inferColumns(rows) {\n  var columnSet = Object.create(null),\n      columns = [];\n\n  rows.forEach(function(row) {\n    for (var column in row) {\n      if (!(column in columnSet)) {\n        columns.push(columnSet[column] = column);\n      }\n    }\n  });\n\n  return columns;\n}\n\nfunction pad(value, width) {\n  var s = value + \"\", length = s.length;\n  return length < width ? new Array(width - length + 1).join(0) + s : s;\n}\n\nfunction formatYear(year) {\n  return year < 0 ? \"-\" + pad(-year, 6)\n    : year > 9999 ? \"+\" + pad(year, 6)\n    : pad(year, 4);\n}\n\nfunction formatDate(date) {\n  var hours = date.getUTCHours(),\n      minutes = date.getUTCMinutes(),\n      seconds = date.getUTCSeconds(),\n      milliseconds = date.getUTCMilliseconds();\n  return isNaN(date) ? \"Invalid Date\"\n      : formatYear(date.getUTCFullYear(), 4) + \"-\" + pad(date.getUTCMonth() + 1, 2) + \"-\" + pad(date.getUTCDate(), 2)\n      + (milliseconds ? \"T\" + pad(hours, 2) + \":\" + pad(minutes, 2) + \":\" + pad(seconds, 2) + \".\" + pad(milliseconds, 3) + \"Z\"\n      : seconds ? \"T\" + pad(hours, 2) + \":\" + pad(minutes, 2) + \":\" + pad(seconds, 2) + \"Z\"\n      : minutes || hours ? \"T\" + pad(hours, 2) + \":\" + pad(minutes, 2) + \"Z\"\n      : \"\");\n}\n\nexport default function(delimiter) {\n  var reFormat = new RegExp(\"[\\\"\" + delimiter + \"\\n\\r]\"),\n      DELIMITER = delimiter.charCodeAt(0);\n\n  function parse(text, f) {\n    var convert, columns, rows = parseRows(text, function(row, i) {\n      if (convert) return convert(row, i - 1);\n      columns = row, convert = f ? customConverter(row, f) : objectConverter(row);\n    });\n    rows.columns = columns || [];\n    return rows;\n  }\n\n  function parseRows(text, f) {\n    var rows = [], // output rows\n        N = text.length,\n        I = 0, // current character index\n        n = 0, // current line number\n        t, // current token\n        eof = N <= 0, // current token followed by EOF?\n        eol = false; // current token followed by EOL?\n\n    // Strip the trailing newline.\n    if (text.charCodeAt(N - 1) === NEWLINE) --N;\n    if (text.charCodeAt(N - 1) === RETURN) --N;\n\n    function token() {\n      if (eof) return EOF;\n      if (eol) return eol = false, EOL;\n\n      // Unescape quotes.\n      var i, j = I, c;\n      if (text.charCodeAt(j) === QUOTE) {\n        while (I++ < N && text.charCodeAt(I) !== QUOTE || text.charCodeAt(++I) === QUOTE);\n        if ((i = I) >= N) eof = true;\n        else if ((c = text.charCodeAt(I++)) === NEWLINE) eol = true;\n        else if (c === RETURN) { eol = true; if (text.charCodeAt(I) === NEWLINE) ++I; }\n        return text.slice(j + 1, i - 1).replace(/\"\"/g, \"\\\"\");\n      }\n\n      // Find next delimiter or newline.\n      while (I < N) {\n        if ((c = text.charCodeAt(i = I++)) === NEWLINE) eol = true;\n        else if (c === RETURN) { eol = true; if (text.charCodeAt(I) === NEWLINE) ++I; }\n        else if (c !== DELIMITER) continue;\n        return text.slice(j, i);\n      }\n\n      // Return last token before EOF.\n      return eof = true, text.slice(j, N);\n    }\n\n    while ((t = token()) !== EOF) {\n      var row = [];\n      while (t !== EOL && t !== EOF) row.push(t), t = token();\n      if (f && (row = f(row, n++)) == null) continue;\n      rows.push(row);\n    }\n\n    return rows;\n  }\n\n  function preformatBody(rows, columns) {\n    return rows.map(function(row) {\n      return columns.map(function(column) {\n        return formatValue(row[column]);\n      }).join(delimiter);\n    });\n  }\n\n  function format(rows, columns) {\n    if (columns == null) columns = inferColumns(rows);\n    return [columns.map(formatValue).join(delimiter)].concat(preformatBody(rows, columns)).join(\"\\n\");\n  }\n\n  function formatBody(rows, columns) {\n    if (columns == null) columns = inferColumns(rows);\n    return preformatBody(rows, columns).join(\"\\n\");\n  }\n\n  function formatRows(rows) {\n    return rows.map(formatRow).join(\"\\n\");\n  }\n\n  function formatRow(row) {\n    return row.map(formatValue).join(delimiter);\n  }\n\n  function formatValue(value) {\n    return value == null ? \"\"\n        : value instanceof Date ? formatDate(value)\n        : reFormat.test(value += \"\") ? \"\\\"\" + value.replace(/\"/g, \"\\\"\\\"\") + \"\\\"\"\n        : value;\n  }\n\n  return {\n    parse: parse,\n    parseRows: parseRows,\n    format: format,\n    formatBody: formatBody,\n    formatRows: formatRows,\n    formatRow: formatRow,\n    formatValue: formatValue\n  };\n}\n","import dsv from \"./dsv.js\";\n\nvar csv = dsv(\",\");\n\nexport var csvParse = csv.parse;\nexport var csvParseRows = csv.parseRows;\nexport var csvFormat = csv.format;\nexport var csvFormatBody = csv.formatBody;\nexport var csvFormatRows = csv.formatRows;\nexport var csvFormatRow = csv.formatRow;\nexport var csvFormatValue = csv.formatValue;\n","import dsv from \"./dsv.js\";\n\nvar tsv = dsv(\"\\t\");\n\nexport var tsvParse = tsv.parse;\nexport var tsvParseRows = tsv.parseRows;\nexport var tsvFormat = tsv.format;\nexport var tsvFormatBody = tsv.formatBody;\nexport var tsvFormatRows = tsv.formatRows;\nexport var tsvFormatRow = tsv.formatRow;\nexport var tsvFormatValue = tsv.formatValue;\n","function responseText(response) {\n  if (!response.ok) throw new Error(response.status + \" \" + response.statusText);\n  return response.text();\n}\n\nexport default function(input, init) {\n  return fetch(input, init).then(responseText);\n}\n","import {csvParse, dsvFormat, tsvParse} from \"d3-dsv\";\nimport text from \"./text\";\n\nfunction dsvParse(parse) {\n  return function(input, init, row) {\n    if (arguments.length === 2 && typeof init === \"function\") row = init, init = undefined;\n    return text(input, init).then(function(response) {\n      return parse(response, row);\n    });\n  };\n}\n\nexport default function dsv(delimiter, input, init, row) {\n  if (arguments.length === 3 && typeof init === \"function\") row = init, init = undefined;\n  var format = dsvFormat(delimiter);\n  return text(input, init).then(function(response) {\n    return format.parse(response, row);\n  });\n}\n\nexport var csv = dsvParse(csvParse);\nexport var tsv = dsvParse(tsvParse);\n","export default function(input, init) {\n  return new Promise(function(resolve, reject) {\n    var image = new Image;\n    for (var key in init) image[key] = init[key];\n    image.onerror = reject;\n    image.onload = function() { resolve(image); };\n    image.src = input;\n  });\n}\n","function responseJson(response) {\n  if (!response.ok) throw new Error(response.status + \" \" + response.statusText);\n  return response.json();\n}\n\nexport default function(input, init) {\n  return fetch(input, init).then(responseJson);\n}\n","import text from \"./text\";\n\nfunction parser(type) {\n  return function(input, init)  {\n    return text(input, init).then(function(text) {\n      return (new DOMParser).parseFromString(text, type);\n    });\n  };\n}\n\nexport default parser(\"application/xml\");\n\nexport var html = parser(\"text/html\");\n\nexport var svg = parser(\"image/svg+xml\");\n","var noop = {value: function() {}};\n\nfunction dispatch() {\n  for (var i = 0, n = arguments.length, _ = {}, t; i < n; ++i) {\n    if (!(t = arguments[i] + \"\") || (t in _) || /[\\s.]/.test(t)) throw new Error(\"illegal type: \" + t);\n    _[t] = [];\n  }\n  return new Dispatch(_);\n}\n\nfunction Dispatch(_) {\n  this._ = _;\n}\n\nfunction parseTypenames(typenames, types) {\n  return typenames.trim().split(/^|\\s+/).map(function(t) {\n    var name = \"\", i = t.indexOf(\".\");\n    if (i >= 0) name = t.slice(i + 1), t = t.slice(0, i);\n    if (t && !types.hasOwnProperty(t)) throw new Error(\"unknown type: \" + t);\n    return {type: t, name: name};\n  });\n}\n\nDispatch.prototype = dispatch.prototype = {\n  constructor: Dispatch,\n  on: function(typename, callback) {\n    var _ = this._,\n        T = parseTypenames(typename + \"\", _),\n        t,\n        i = -1,\n        n = T.length;\n\n    // If no callback was specified, return the callback of the given type and name.\n    if (arguments.length < 2) {\n      while (++i < n) if ((t = (typename = T[i]).type) && (t = get(_[t], typename.name))) return t;\n      return;\n    }\n\n    // If a type was specified, set the callback for the given type and name.\n    // Otherwise, if a null callback was specified, remove callbacks of the given name.\n    if (callback != null && typeof callback !== \"function\") throw new Error(\"invalid callback: \" + callback);\n    while (++i < n) {\n      if (t = (typename = T[i]).type) _[t] = set(_[t], typename.name, callback);\n      else if (callback == null) for (t in _) _[t] = set(_[t], typename.name, null);\n    }\n\n    return this;\n  },\n  copy: function() {\n    var copy = {}, _ = this._;\n    for (var t in _) copy[t] = _[t].slice();\n    return new Dispatch(copy);\n  },\n  call: function(type, that) {\n    if ((n = arguments.length - 2) > 0) for (var args = new Array(n), i = 0, n, t; i < n; ++i) args[i] = arguments[i + 2];\n    if (!this._.hasOwnProperty(type)) throw new Error(\"unknown type: \" + type);\n    for (t = this._[type], i = 0, n = t.length; i < n; ++i) t[i].value.apply(that, args);\n  },\n  apply: function(type, that, args) {\n    if (!this._.hasOwnProperty(type)) throw new Error(\"unknown type: \" + type);\n    for (var t = this._[type], i = 0, n = t.length; i < n; ++i) t[i].value.apply(that, args);\n  }\n};\n\nfunction get(type, name) {\n  for (var i = 0, n = type.length, c; i < n; ++i) {\n    if ((c = type[i]).name === name) {\n      return c.value;\n    }\n  }\n}\n\nfunction set(type, name, callback) {\n  for (var i = 0, n = type.length; i < n; ++i) {\n    if (type[i].name === name) {\n      type[i] = noop, type = type.slice(0, i).concat(type.slice(i + 1));\n      break;\n    }\n  }\n  if (callback != null) type.push({name: name, value: callback});\n  return type;\n}\n\nexport default dispatch;\n","import {event} from \"d3-selection\";\n\nexport function nopropagation() {\n  event.stopImmediatePropagation();\n}\n\nexport default function() {\n  event.preventDefault();\n  event.stopImmediatePropagation();\n}\n","import {select} from \"d3-selection\";\nimport noevent from \"./noevent.js\";\n\nexport default function(view) {\n  var root = view.document.documentElement,\n      selection = select(view).on(\"dragstart.drag\", noevent, true);\n  if (\"onselectstart\" in root) {\n    selection.on(\"selectstart.drag\", noevent, true);\n  } else {\n    root.__noselect = root.style.MozUserSelect;\n    root.style.MozUserSelect = \"none\";\n  }\n}\n\nexport function yesdrag(view, noclick) {\n  var root = view.document.documentElement,\n      selection = select(view).on(\"dragstart.drag\", null);\n  if (noclick) {\n    selection.on(\"click.drag\", noevent, true);\n    setTimeout(function() { selection.on(\"click.drag\", null); }, 0);\n  }\n  if (\"onselectstart\" in root) {\n    selection.on(\"selectstart.drag\", null);\n  } else {\n    root.style.MozUserSelect = root.__noselect;\n    delete root.__noselect;\n  }\n}\n","export default function(constructor, factory, prototype) {\n  constructor.prototype = factory.prototype = prototype;\n  prototype.constructor = constructor;\n}\n\nexport function extend(parent, definition) {\n  var prototype = Object.create(parent.prototype);\n  for (var key in definition) prototype[key] = definition[key];\n  return prototype;\n}\n","import define, {extend} from \"./define.js\";\n\nexport function Color() {}\n\nexport var darker = 0.7;\nexport var brighter = 1 / darker;\n\nvar reI = \"\\\\s*([+-]?\\\\d+)\\\\s*\",\n    reN = \"\\\\s*([+-]?\\\\d*\\\\.?\\\\d+(?:[eE][+-]?\\\\d+)?)\\\\s*\",\n    reP = \"\\\\s*([+-]?\\\\d*\\\\.?\\\\d+(?:[eE][+-]?\\\\d+)?)%\\\\s*\",\n    reHex = /^#([0-9a-f]{3,8})$/,\n    reRgbInteger = new RegExp(\"^rgb\\\\(\" + [reI, reI, reI] + \"\\\\)$\"),\n    reRgbPercent = new RegExp(\"^rgb\\\\(\" + [reP, reP, reP] + \"\\\\)$\"),\n    reRgbaInteger = new RegExp(\"^rgba\\\\(\" + [reI, reI, reI, reN] + \"\\\\)$\"),\n    reRgbaPercent = new RegExp(\"^rgba\\\\(\" + [reP, reP, reP, reN] + \"\\\\)$\"),\n    reHslPercent = new RegExp(\"^hsl\\\\(\" + [reN, reP, reP] + \"\\\\)$\"),\n    reHslaPercent = new RegExp(\"^hsla\\\\(\" + [reN, reP, reP, reN] + \"\\\\)$\");\n\nvar named = {\n  aliceblue: 0xf0f8ff,\n  antiquewhite: 0xfaebd7,\n  aqua: 0x00ffff,\n  aquamarine: 0x7fffd4,\n  azure: 0xf0ffff,\n  beige: 0xf5f5dc,\n  bisque: 0xffe4c4,\n  black: 0x000000,\n  blanchedalmond: 0xffebcd,\n  blue: 0x0000ff,\n  blueviolet: 0x8a2be2,\n  brown: 0xa52a2a,\n  burlywood: 0xdeb887,\n  cadetblue: 0x5f9ea0,\n  chartreuse: 0x7fff00,\n  chocolate: 0xd2691e,\n  coral: 0xff7f50,\n  cornflowerblue: 0x6495ed,\n  cornsilk: 0xfff8dc,\n  crimson: 0xdc143c,\n  cyan: 0x00ffff,\n  darkblue: 0x00008b,\n  darkcyan: 0x008b8b,\n  darkgoldenrod: 0xb8860b,\n  darkgray: 0xa9a9a9,\n  darkgreen: 0x006400,\n  darkgrey: 0xa9a9a9,\n  darkkhaki: 0xbdb76b,\n  darkmagenta: 0x8b008b,\n  darkolivegreen: 0x556b2f,\n  darkorange: 0xff8c00,\n  darkorchid: 0x9932cc,\n  darkred: 0x8b0000,\n  darksalmon: 0xe9967a,\n  darkseagreen: 0x8fbc8f,\n  darkslateblue: 0x483d8b,\n  darkslategray: 0x2f4f4f,\n  darkslategrey: 0x2f4f4f,\n  darkturquoise: 0x00ced1,\n  darkviolet: 0x9400d3,\n  deeppink: 0xff1493,\n  deepskyblue: 0x00bfff,\n  dimgray: 0x696969,\n  dimgrey: 0x696969,\n  dodgerblue: 0x1e90ff,\n  firebrick: 0xb22222,\n  floralwhite: 0xfffaf0,\n  forestgreen: 0x228b22,\n  fuchsia: 0xff00ff,\n  gainsboro: 0xdcdcdc,\n  ghostwhite: 0xf8f8ff,\n  gold: 0xffd700,\n  goldenrod: 0xdaa520,\n  gray: 0x808080,\n  green: 0x008000,\n  greenyellow: 0xadff2f,\n  grey: 0x808080,\n  honeydew: 0xf0fff0,\n  hotpink: 0xff69b4,\n  indianred: 0xcd5c5c,\n  indigo: 0x4b0082,\n  ivory: 0xfffff0,\n  khaki: 0xf0e68c,\n  lavender: 0xe6e6fa,\n  lavenderblush: 0xfff0f5,\n  lawngreen: 0x7cfc00,\n  lemonchiffon: 0xfffacd,\n  lightblue: 0xadd8e6,\n  lightcoral: 0xf08080,\n  lightcyan: 0xe0ffff,\n  lightgoldenrodyellow: 0xfafad2,\n  lightgray: 0xd3d3d3,\n  lightgreen: 0x90ee90,\n  lightgrey: 0xd3d3d3,\n  lightpink: 0xffb6c1,\n  lightsalmon: 0xffa07a,\n  lightseagreen: 0x20b2aa,\n  lightskyblue: 0x87cefa,\n  lightslategray: 0x778899,\n  lightslategrey: 0x778899,\n  lightsteelblue: 0xb0c4de,\n  lightyellow: 0xffffe0,\n  lime: 0x00ff00,\n  limegreen: 0x32cd32,\n  linen: 0xfaf0e6,\n  magenta: 0xff00ff,\n  maroon: 0x800000,\n  mediumaquamarine: 0x66cdaa,\n  mediumblue: 0x0000cd,\n  mediumorchid: 0xba55d3,\n  mediumpurple: 0x9370db,\n  mediumseagreen: 0x3cb371,\n  mediumslateblue: 0x7b68ee,\n  mediumspringgreen: 0x00fa9a,\n  mediumturquoise: 0x48d1cc,\n  mediumvioletred: 0xc71585,\n  midnightblue: 0x191970,\n  mintcream: 0xf5fffa,\n  mistyrose: 0xffe4e1,\n  moccasin: 0xffe4b5,\n  navajowhite: 0xffdead,\n  navy: 0x000080,\n  oldlace: 0xfdf5e6,\n  olive: 0x808000,\n  olivedrab: 0x6b8e23,\n  orange: 0xffa500,\n  orangered: 0xff4500,\n  orchid: 0xda70d6,\n  palegoldenrod: 0xeee8aa,\n  palegreen: 0x98fb98,\n  paleturquoise: 0xafeeee,\n  palevioletred: 0xdb7093,\n  papayawhip: 0xffefd5,\n  peachpuff: 0xffdab9,\n  peru: 0xcd853f,\n  pink: 0xffc0cb,\n  plum: 0xdda0dd,\n  powderblue: 0xb0e0e6,\n  purple: 0x800080,\n  rebeccapurple: 0x663399,\n  red: 0xff0000,\n  rosybrown: 0xbc8f8f,\n  royalblue: 0x4169e1,\n  saddlebrown: 0x8b4513,\n  salmon: 0xfa8072,\n  sandybrown: 0xf4a460,\n  seagreen: 0x2e8b57,\n  seashell: 0xfff5ee,\n  sienna: 0xa0522d,\n  silver: 0xc0c0c0,\n  skyblue: 0x87ceeb,\n  slateblue: 0x6a5acd,\n  slategray: 0x708090,\n  slategrey: 0x708090,\n  snow: 0xfffafa,\n  springgreen: 0x00ff7f,\n  steelblue: 0x4682b4,\n  tan: 0xd2b48c,\n  teal: 0x008080,\n  thistle: 0xd8bfd8,\n  tomato: 0xff6347,\n  turquoise: 0x40e0d0,\n  violet: 0xee82ee,\n  wheat: 0xf5deb3,\n  white: 0xffffff,\n  whitesmoke: 0xf5f5f5,\n  yellow: 0xffff00,\n  yellowgreen: 0x9acd32\n};\n\ndefine(Color, color, {\n  copy: function(channels) {\n    return Object.assign(new this.constructor, this, channels);\n  },\n  displayable: function() {\n    return this.rgb().displayable();\n  },\n  hex: color_formatHex, // Deprecated! Use color.formatHex.\n  formatHex: color_formatHex,\n  formatHsl: color_formatHsl,\n  formatRgb: color_formatRgb,\n  toString: color_formatRgb\n});\n\nfunction color_formatHex() {\n  return this.rgb().formatHex();\n}\n\nfunction color_formatHsl() {\n  return hslConvert(this).formatHsl();\n}\n\nfunction color_formatRgb() {\n  return this.rgb().formatRgb();\n}\n\nexport default function color(format) {\n  var m, l;\n  format = (format + \"\").trim().toLowerCase();\n  return (m = reHex.exec(format)) ? (l = m[1].length, m = parseInt(m[1], 16), l === 6 ? rgbn(m) // #ff0000\n      : l === 3 ? new Rgb((m >> 8 & 0xf) | (m >> 4 & 0xf0), (m >> 4 & 0xf) | (m & 0xf0), ((m & 0xf) << 4) | (m & 0xf), 1) // #f00\n      : l === 8 ? new Rgb(m >> 24 & 0xff, m >> 16 & 0xff, m >> 8 & 0xff, (m & 0xff) / 0xff) // #ff000000\n      : l === 4 ? new Rgb((m >> 12 & 0xf) | (m >> 8 & 0xf0), (m >> 8 & 0xf) | (m >> 4 & 0xf0), (m >> 4 & 0xf) | (m & 0xf0), (((m & 0xf) << 4) | (m & 0xf)) / 0xff) // #f000\n      : null) // invalid hex\n      : (m = reRgbInteger.exec(format)) ? new Rgb(m[1], m[2], m[3], 1) // rgb(255, 0, 0)\n      : (m = reRgbPercent.exec(format)) ? new Rgb(m[1] * 255 / 100, m[2] * 255 / 100, m[3] * 255 / 100, 1) // rgb(100%, 0%, 0%)\n      : (m = reRgbaInteger.exec(format)) ? rgba(m[1], m[2], m[3], m[4]) // rgba(255, 0, 0, 1)\n      : (m = reRgbaPercent.exec(format)) ? rgba(m[1] * 255 / 100, m[2] * 255 / 100, m[3] * 255 / 100, m[4]) // rgb(100%, 0%, 0%, 1)\n      : (m = reHslPercent.exec(format)) ? hsla(m[1], m[2] / 100, m[3] / 100, 1) // hsl(120, 50%, 50%)\n      : (m = reHslaPercent.exec(format)) ? hsla(m[1], m[2] / 100, m[3] / 100, m[4]) // hsla(120, 50%, 50%, 1)\n      : named.hasOwnProperty(format) ? rgbn(named[format]) // eslint-disable-line no-prototype-builtins\n      : format === \"transparent\" ? new Rgb(NaN, NaN, NaN, 0)\n      : null;\n}\n\nfunction rgbn(n) {\n  return new Rgb(n >> 16 & 0xff, n >> 8 & 0xff, n & 0xff, 1);\n}\n\nfunction rgba(r, g, b, a) {\n  if (a <= 0) r = g = b = NaN;\n  return new Rgb(r, g, b, a);\n}\n\nexport function rgbConvert(o) {\n  if (!(o instanceof Color)) o = color(o);\n  if (!o) return new Rgb;\n  o = o.rgb();\n  return new Rgb(o.r, o.g, o.b, o.opacity);\n}\n\nexport function rgb(r, g, b, opacity) {\n  return arguments.length === 1 ? rgbConvert(r) : new Rgb(r, g, b, opacity == null ? 1 : opacity);\n}\n\nexport function Rgb(r, g, b, opacity) {\n  this.r = +r;\n  this.g = +g;\n  this.b = +b;\n  this.opacity = +opacity;\n}\n\ndefine(Rgb, rgb, extend(Color, {\n  brighter: function(k) {\n    k = k == null ? brighter : Math.pow(brighter, k);\n    return new Rgb(this.r * k, this.g * k, this.b * k, this.opacity);\n  },\n  darker: function(k) {\n    k = k == null ? darker : Math.pow(darker, k);\n    return new Rgb(this.r * k, this.g * k, this.b * k, this.opacity);\n  },\n  rgb: function() {\n    return this;\n  },\n  displayable: function() {\n    return (-0.5 <= this.r && this.r < 255.5)\n        && (-0.5 <= this.g && this.g < 255.5)\n        && (-0.5 <= this.b && this.b < 255.5)\n        && (0 <= this.opacity && this.opacity <= 1);\n  },\n  hex: rgb_formatHex, // Deprecated! Use color.formatHex.\n  formatHex: rgb_formatHex,\n  formatRgb: rgb_formatRgb,\n  toString: rgb_formatRgb\n}));\n\nfunction rgb_formatHex() {\n  return \"#\" + hex(this.r) + hex(this.g) + hex(this.b);\n}\n\nfunction rgb_formatRgb() {\n  var a = this.opacity; a = isNaN(a) ? 1 : Math.max(0, Math.min(1, a));\n  return (a === 1 ? \"rgb(\" : \"rgba(\")\n      + Math.max(0, Math.min(255, Math.round(this.r) || 0)) + \", \"\n      + Math.max(0, Math.min(255, Math.round(this.g) || 0)) + \", \"\n      + Math.max(0, Math.min(255, Math.round(this.b) || 0))\n      + (a === 1 ? \")\" : \", \" + a + \")\");\n}\n\nfunction hex(value) {\n  value = Math.max(0, Math.min(255, Math.round(value) || 0));\n  return (value < 16 ? \"0\" : \"\") + value.toString(16);\n}\n\nfunction hsla(h, s, l, a) {\n  if (a <= 0) h = s = l = NaN;\n  else if (l <= 0 || l >= 1) h = s = NaN;\n  else if (s <= 0) h = NaN;\n  return new Hsl(h, s, l, a);\n}\n\nexport function hslConvert(o) {\n  if (o instanceof Hsl) return new Hsl(o.h, o.s, o.l, o.opacity);\n  if (!(o instanceof Color)) o = color(o);\n  if (!o) return new Hsl;\n  if (o instanceof Hsl) return o;\n  o = o.rgb();\n  var r = o.r / 255,\n      g = o.g / 255,\n      b = o.b / 255,\n      min = Math.min(r, g, b),\n      max = Math.max(r, g, b),\n      h = NaN,\n      s = max - min,\n      l = (max + min) / 2;\n  if (s) {\n    if (r === max) h = (g - b) / s + (g < b) * 6;\n    else if (g === max) h = (b - r) / s + 2;\n    else h = (r - g) / s + 4;\n    s /= l < 0.5 ? max + min : 2 - max - min;\n    h *= 60;\n  } else {\n    s = l > 0 && l < 1 ? 0 : h;\n  }\n  return new Hsl(h, s, l, o.opacity);\n}\n\nexport function hsl(h, s, l, opacity) {\n  return arguments.length === 1 ? hslConvert(h) : new Hsl(h, s, l, opacity == null ? 1 : opacity);\n}\n\nfunction Hsl(h, s, l, opacity) {\n  this.h = +h;\n  this.s = +s;\n  this.l = +l;\n  this.opacity = +opacity;\n}\n\ndefine(Hsl, hsl, extend(Color, {\n  brighter: function(k) {\n    k = k == null ? brighter : Math.pow(brighter, k);\n    return new Hsl(this.h, this.s, this.l * k, this.opacity);\n  },\n  darker: function(k) {\n    k = k == null ? darker : Math.pow(darker, k);\n    return new Hsl(this.h, this.s, this.l * k, this.opacity);\n  },\n  rgb: function() {\n    var h = this.h % 360 + (this.h < 0) * 360,\n        s = isNaN(h) || isNaN(this.s) ? 0 : this.s,\n        l = this.l,\n        m2 = l + (l < 0.5 ? l : 1 - l) * s,\n        m1 = 2 * l - m2;\n    return new Rgb(\n      hsl2rgb(h >= 240 ? h - 240 : h + 120, m1, m2),\n      hsl2rgb(h, m1, m2),\n      hsl2rgb(h < 120 ? h + 240 : h - 120, m1, m2),\n      this.opacity\n    );\n  },\n  displayable: function() {\n    return (0 <= this.s && this.s <= 1 || isNaN(this.s))\n        && (0 <= this.l && this.l <= 1)\n        && (0 <= this.opacity && this.opacity <= 1);\n  },\n  formatHsl: function() {\n    var a = this.opacity; a = isNaN(a) ? 1 : Math.max(0, Math.min(1, a));\n    return (a === 1 ? \"hsl(\" : \"hsla(\")\n        + (this.h || 0) + \", \"\n        + (this.s || 0) * 100 + \"%, \"\n        + (this.l || 0) * 100 + \"%\"\n        + (a === 1 ? \")\" : \", \" + a + \")\");\n  }\n}));\n\n/* From FvD 13.37, CSS Color Module Level 3 */\nfunction hsl2rgb(h, m1, m2) {\n  return (h < 60 ? m1 + (m2 - m1) * h / 60\n      : h < 180 ? m2\n      : h < 240 ? m1 + (m2 - m1) * (240 - h) / 60\n      : m1) * 255;\n}\n","export function basis(t1, v0, v1, v2, v3) {\n  var t2 = t1 * t1, t3 = t2 * t1;\n  return ((1 - 3 * t1 + 3 * t2 - t3) * v0\n      + (4 - 6 * t2 + 3 * t3) * v1\n      + (1 + 3 * t1 + 3 * t2 - 3 * t3) * v2\n      + t3 * v3) / 6;\n}\n\nexport default function(values) {\n  var n = values.length - 1;\n  return function(t) {\n    var i = t <= 0 ? (t = 0) : t >= 1 ? (t = 1, n - 1) : Math.floor(t * n),\n        v1 = values[i],\n        v2 = values[i + 1],\n        v0 = i > 0 ? values[i - 1] : 2 * v1 - v2,\n        v3 = i < n - 1 ? values[i + 2] : 2 * v2 - v1;\n    return basis((t - i / n) * n, v0, v1, v2, v3);\n  };\n}\n","export default function(x) {\n  return function() {\n    return x;\n  };\n}\n","import constant from \"./constant.js\";\n\nfunction linear(a, d) {\n  return function(t) {\n    return a + t * d;\n  };\n}\n\nfunction exponential(a, b, y) {\n  return a = Math.pow(a, y), b = Math.pow(b, y) - a, y = 1 / y, function(t) {\n    return Math.pow(a + t * b, y);\n  };\n}\n\nexport function hue(a, b) {\n  var d = b - a;\n  return d ? linear(a, d > 180 || d < -180 ? d - 360 * Math.round(d / 360) : d) : constant(isNaN(a) ? b : a);\n}\n\nexport function gamma(y) {\n  return (y = +y) === 1 ? nogamma : function(a, b) {\n    return b - a ? exponential(a, b, y) : constant(isNaN(a) ? b : a);\n  };\n}\n\nexport default function nogamma(a, b) {\n  var d = b - a;\n  return d ? linear(a, d) : constant(isNaN(a) ? b : a);\n}\n","import {rgb as colorRgb} from \"d3-color\";\nimport basis from \"./basis.js\";\nimport basisClosed from \"./basisClosed.js\";\nimport nogamma, {gamma} from \"./color.js\";\n\nexport default (function rgbGamma(y) {\n  var color = gamma(y);\n\n  function rgb(start, end) {\n    var r = color((start = colorRgb(start)).r, (end = colorRgb(end)).r),\n        g = color(start.g, end.g),\n        b = color(start.b, end.b),\n        opacity = nogamma(start.opacity, end.opacity);\n    return function(t) {\n      start.r = r(t);\n      start.g = g(t);\n      start.b = b(t);\n      start.opacity = opacity(t);\n      return start + \"\";\n    };\n  }\n\n  rgb.gamma = rgbGamma;\n\n  return rgb;\n})(1);\n\nfunction rgbSpline(spline) {\n  return function(colors) {\n    var n = colors.length,\n        r = new Array(n),\n        g = new Array(n),\n        b = new Array(n),\n        i, color;\n    for (i = 0; i < n; ++i) {\n      color = colorRgb(colors[i]);\n      r[i] = color.r || 0;\n      g[i] = color.g || 0;\n      b[i] = color.b || 0;\n    }\n    r = spline(r);\n    g = spline(g);\n    b = spline(b);\n    color.opacity = 1;\n    return function(t) {\n      color.r = r(t);\n      color.g = g(t);\n      color.b = b(t);\n      return color + \"\";\n    };\n  };\n}\n\nexport var rgbBasis = rgbSpline(basis);\nexport var rgbBasisClosed = rgbSpline(basisClosed);\n","import {basis} from \"./basis.js\";\n\nexport default function(values) {\n  var n = values.length;\n  return function(t) {\n    var i = Math.floor(((t %= 1) < 0 ? ++t : t) * n),\n        v0 = values[(i + n - 1) % n],\n        v1 = values[i % n],\n        v2 = values[(i + 1) % n],\n        v3 = values[(i + 2) % n];\n    return basis((t - i / n) * n, v0, v1, v2, v3);\n  };\n}\n","export default function(a, b) {\n  if (!b) b = [];\n  var n = a ? Math.min(b.length, a.length) : 0,\n      c = b.slice(),\n      i;\n  return function(t) {\n    for (i = 0; i < n; ++i) c[i] = a[i] * (1 - t) + b[i] * t;\n    return c;\n  };\n}\n\nexport function isNumberArray(x) {\n  return ArrayBuffer.isView(x) && !(x instanceof DataView);\n}\n","import value from \"./value.js\";\nimport numberArray, {isNumberArray} from \"./numberArray.js\";\n\nexport default function(a, b) {\n  return (isNumberArray(b) ? numberArray : genericArray)(a, b);\n}\n\nexport function genericArray(a, b) {\n  var nb = b ? b.length : 0,\n      na = a ? Math.min(nb, a.length) : 0,\n      x = new Array(na),\n      c = new Array(nb),\n      i;\n\n  for (i = 0; i < na; ++i) x[i] = value(a[i], b[i]);\n  for (; i < nb; ++i) c[i] = b[i];\n\n  return function(t) {\n    for (i = 0; i < na; ++i) c[i] = x[i](t);\n    return c;\n  };\n}\n","export default function(a, b) {\n  var d = new Date;\n  return a = +a, b = +b, function(t) {\n    return d.setTime(a * (1 - t) + b * t), d;\n  };\n}\n","export default function(a, b) {\n  return a = +a, b = +b, function(t) {\n    return a * (1 - t) + b * t;\n  };\n}\n","import value from \"./value.js\";\n\nexport default function(a, b) {\n  var i = {},\n      c = {},\n      k;\n\n  if (a === null || typeof a !== \"object\") a = {};\n  if (b === null || typeof b !== \"object\") b = {};\n\n  for (k in b) {\n    if (k in a) {\n      i[k] = value(a[k], b[k]);\n    } else {\n      c[k] = b[k];\n    }\n  }\n\n  return function(t) {\n    for (k in i) c[k] = i[k](t);\n    return c;\n  };\n}\n","import number from \"./number.js\";\n\nvar reA = /[-+]?(?:\\d+\\.?\\d*|\\.?\\d+)(?:[eE][-+]?\\d+)?/g,\n    reB = new RegExp(reA.source, \"g\");\n\nfunction zero(b) {\n  return function() {\n    return b;\n  };\n}\n\nfunction one(b) {\n  return function(t) {\n    return b(t) + \"\";\n  };\n}\n\nexport default function(a, b) {\n  var bi = reA.lastIndex = reB.lastIndex = 0, // scan index for next number in b\n      am, // current match in a\n      bm, // current match in b\n      bs, // string preceding current number in b, if any\n      i = -1, // index in s\n      s = [], // string constants and placeholders\n      q = []; // number interpolators\n\n  // Coerce inputs to strings.\n  a = a + \"\", b = b + \"\";\n\n  // Interpolate pairs of numbers in a & b.\n  while ((am = reA.exec(a))\n      && (bm = reB.exec(b))) {\n    if ((bs = bm.index) > bi) { // a string precedes the next number in b\n      bs = b.slice(bi, bs);\n      if (s[i]) s[i] += bs; // coalesce with previous string\n      else s[++i] = bs;\n    }\n    if ((am = am[0]) === (bm = bm[0])) { // numbers in a & b match\n      if (s[i]) s[i] += bm; // coalesce with previous string\n      else s[++i] = bm;\n    } else { // interpolate non-matching numbers\n      s[++i] = null;\n      q.push({i: i, x: number(am, bm)});\n    }\n    bi = reB.lastIndex;\n  }\n\n  // Add remains of b.\n  if (bi < b.length) {\n    bs = b.slice(bi);\n    if (s[i]) s[i] += bs; // coalesce with previous string\n    else s[++i] = bs;\n  }\n\n  // Special optimization for only a single match.\n  // Otherwise, interpolate each of the numbers and rejoin the string.\n  return s.length < 2 ? (q[0]\n      ? one(q[0].x)\n      : zero(b))\n      : (b = q.length, function(t) {\n          for (var i = 0, o; i < b; ++i) s[(o = q[i]).i] = o.x(t);\n          return s.join(\"\");\n        });\n}\n","var frame = 0, // is an animation frame pending?\n    timeout = 0, // is a timeout pending?\n    interval = 0, // are any timers active?\n    pokeDelay = 1000, // how frequently we check for clock skew\n    taskHead,\n    taskTail,\n    clockLast = 0,\n    clockNow = 0,\n    clockSkew = 0,\n    clock = typeof performance === \"object\" && performance.now ? performance : Date,\n    setFrame = typeof window === \"object\" && window.requestAnimationFrame ? window.requestAnimationFrame.bind(window) : function(f) { setTimeout(f, 17); };\n\nexport function now() {\n  return clockNow || (setFrame(clearNow), clockNow = clock.now() + clockSkew);\n}\n\nfunction clearNow() {\n  clockNow = 0;\n}\n\nexport function Timer() {\n  this._call =\n  this._time =\n  this._next = null;\n}\n\nTimer.prototype = timer.prototype = {\n  constructor: Timer,\n  restart: function(callback, delay, time) {\n    if (typeof callback !== \"function\") throw new TypeError(\"callback is not a function\");\n    time = (time == null ? now() : +time) + (delay == null ? 0 : +delay);\n    if (!this._next && taskTail !== this) {\n      if (taskTail) taskTail._next = this;\n      else taskHead = this;\n      taskTail = this;\n    }\n    this._call = callback;\n    this._time = time;\n    sleep();\n  },\n  stop: function() {\n    if (this._call) {\n      this._call = null;\n      this._time = Infinity;\n      sleep();\n    }\n  }\n};\n\nexport function timer(callback, delay, time) {\n  var t = new Timer;\n  t.restart(callback, delay, time);\n  return t;\n}\n\nexport function timerFlush() {\n  now(); // Get the current time, if not already set.\n  ++frame; // Pretend we’ve set an alarm, if we haven’t already.\n  var t = taskHead, e;\n  while (t) {\n    if ((e = clockNow - t._time) >= 0) t._call.call(null, e);\n    t = t._next;\n  }\n  --frame;\n}\n\nfunction wake() {\n  clockNow = (clockLast = clock.now()) + clockSkew;\n  frame = timeout = 0;\n  try {\n    timerFlush();\n  } finally {\n    frame = 0;\n    nap();\n    clockNow = 0;\n  }\n}\n\nfunction poke() {\n  var now = clock.now(), delay = now - clockLast;\n  if (delay > pokeDelay) clockSkew -= delay, clockLast = now;\n}\n\nfunction nap() {\n  var t0, t1 = taskHead, t2, time = Infinity;\n  while (t1) {\n    if (t1._call) {\n      if (time > t1._time) time = t1._time;\n      t0 = t1, t1 = t1._next;\n    } else {\n      t2 = t1._next, t1._next = null;\n      t1 = t0 ? t0._next = t2 : taskHead = t2;\n    }\n  }\n  taskTail = t0;\n  sleep(time);\n}\n\nfunction sleep(time) {\n  if (frame) return; // Soonest alarm already set, or will be.\n  if (timeout) timeout = clearTimeout(timeout);\n  var delay = time - clockNow; // Strictly less than if we recomputed clockNow.\n  if (delay > 24) {\n    if (time < Infinity) timeout = setTimeout(wake, time - clock.now() - clockSkew);\n    if (interval) interval = clearInterval(interval);\n  } else {\n    if (!interval) clockLast = clock.now(), interval = setInterval(poke, pokeDelay);\n    frame = 1, setFrame(wake);\n  }\n}\n","import {color} from \"d3-color\";\nimport rgb from \"./rgb.js\";\nimport {genericArray} from \"./array.js\";\nimport date from \"./date.js\";\nimport number from \"./number.js\";\nimport object from \"./object.js\";\nimport string from \"./string.js\";\nimport constant from \"./constant.js\";\nimport numberArray, {isNumberArray} from \"./numberArray.js\";\n\nexport default function(a, b) {\n  var t = typeof b, c;\n  return b == null || t === \"boolean\" ? constant(b)\n      : (t === \"number\" ? number\n      : t === \"string\" ? ((c = color(b)) ? (b = c, rgb) : string)\n      : b instanceof color ? rgb\n      : b instanceof Date ? date\n      : isNumberArray(b) ? numberArray\n      : Array.isArray(b) ? genericArray\n      : typeof b.valueOf !== \"function\" && typeof b.toString !== \"function\" || isNaN(b) ? object\n      : number)(a, b);\n}\n","import {event} from \"./selection/on\";\n\nexport default function() {\n  var current = event, source;\n  while (source = current.sourceEvent) current = source;\n  return current;\n}\n","export default function(node, event) {\n  var svg = node.ownerSVGElement || node;\n\n  if (svg.createSVGPoint) {\n    var point = svg.createSVGPoint();\n    point.x = event.clientX, point.y = event.clientY;\n    point = point.matrixTransform(node.getScreenCTM().inverse());\n    return [point.x, point.y];\n  }\n\n  var rect = node.getBoundingClientRect();\n  return [event.clientX - rect.left - node.clientLeft, event.clientY - rect.top - node.clientTop];\n}\n","import sourceEvent from \"./sourceEvent\";\nimport point from \"./point\";\n\nexport default function(node) {\n  var event = sourceEvent();\n  if (event.changedTouches) event = event.changedTouches[0];\n  return point(node, event);\n}\n","import {Timer} from \"./timer.js\";\n\nexport default function(callback, delay, time) {\n  var t = new Timer;\n  delay = delay == null ? 0 : +delay;\n  t.restart(function(elapsed) {\n    t.stop();\n    callback(elapsed + delay);\n  }, delay, time);\n  return t;\n}\n","import {dispatch} from \"d3-dispatch\";\nimport {timer, timeout} from \"d3-timer\";\n\nvar emptyOn = dispatch(\"start\", \"end\", \"cancel\", \"interrupt\");\nvar emptyTween = [];\n\nexport var CREATED = 0;\nexport var SCHEDULED = 1;\nexport var STARTING = 2;\nexport var STARTED = 3;\nexport var RUNNING = 4;\nexport var ENDING = 5;\nexport var ENDED = 6;\n\nexport default function(node, name, id, index, group, timing) {\n  var schedules = node.__transition;\n  if (!schedules) node.__transition = {};\n  else if (id in schedules) return;\n  create(node, id, {\n    name: name,\n    index: index, // For context during callback.\n    group: group, // For context during callback.\n    on: emptyOn,\n    tween: emptyTween,\n    time: timing.time,\n    delay: timing.delay,\n    duration: timing.duration,\n    ease: timing.ease,\n    timer: null,\n    state: CREATED\n  });\n}\n\nexport function init(node, id) {\n  var schedule = get(node, id);\n  if (schedule.state > CREATED) throw new Error(\"too late; already scheduled\");\n  return schedule;\n}\n\nexport function set(node, id) {\n  var schedule = get(node, id);\n  if (schedule.state > STARTED) throw new Error(\"too late; already running\");\n  return schedule;\n}\n\nexport function get(node, id) {\n  var schedule = node.__transition;\n  if (!schedule || !(schedule = schedule[id])) throw new Error(\"transition not found\");\n  return schedule;\n}\n\nfunction create(node, id, self) {\n  var schedules = node.__transition,\n      tween;\n\n  // Initialize the self timer when the transition is created.\n  // Note the actual delay is not known until the first callback!\n  schedules[id] = self;\n  self.timer = timer(schedule, 0, self.time);\n\n  function schedule(elapsed) {\n    self.state = SCHEDULED;\n    self.timer.restart(start, self.delay, self.time);\n\n    // If the elapsed delay is less than our first sleep, start immediately.\n    if (self.delay <= elapsed) start(elapsed - self.delay);\n  }\n\n  function start(elapsed) {\n    var i, j, n, o;\n\n    // If the state is not SCHEDULED, then we previously errored on start.\n    if (self.state !== SCHEDULED) return stop();\n\n    for (i in schedules) {\n      o = schedules[i];\n      if (o.name !== self.name) continue;\n\n      // While this element already has a starting transition during this frame,\n      // defer starting an interrupting transition until that transition has a\n      // chance to tick (and possibly end); see d3/d3-transition#54!\n      if (o.state === STARTED) return timeout(start);\n\n      // Interrupt the active transition, if any.\n      if (o.state === RUNNING) {\n        o.state = ENDED;\n        o.timer.stop();\n        o.on.call(\"interrupt\", node, node.__data__, o.index, o.group);\n        delete schedules[i];\n      }\n\n      // Cancel any pre-empted transitions.\n      else if (+i < id) {\n        o.state = ENDED;\n        o.timer.stop();\n        o.on.call(\"cancel\", node, node.__data__, o.index, o.group);\n        delete schedules[i];\n      }\n    }\n\n    // Defer the first tick to end of the current frame; see d3/d3#1576.\n    // Note the transition may be canceled after start and before the first tick!\n    // Note this must be scheduled before the start event; see d3/d3-transition#16!\n    // Assuming this is successful, subsequent callbacks go straight to tick.\n    timeout(function() {\n      if (self.state === STARTED) {\n        self.state = RUNNING;\n        self.timer.restart(tick, self.delay, self.time);\n        tick(elapsed);\n      }\n    });\n\n    // Dispatch the start event.\n    // Note this must be done before the tween are initialized.\n    self.state = STARTING;\n    self.on.call(\"start\", node, node.__data__, self.index, self.group);\n    if (self.state !== STARTING) return; // interrupted\n    self.state = STARTED;\n\n    // Initialize the tween, deleting null tween.\n    tween = new Array(n = self.tween.length);\n    for (i = 0, j = -1; i < n; ++i) {\n      if (o = self.tween[i].value.call(node, node.__data__, self.index, self.group)) {\n        tween[++j] = o;\n      }\n    }\n    tween.length = j + 1;\n  }\n\n  function tick(elapsed) {\n    var t = elapsed < self.duration ? self.ease.call(null, elapsed / self.duration) : (self.timer.restart(stop), self.state = ENDING, 1),\n        i = -1,\n        n = tween.length;\n\n    while (++i < n) {\n      tween[i].call(node, t);\n    }\n\n    // Dispatch the end event.\n    if (self.state === ENDING) {\n      self.on.call(\"end\", node, node.__data__, self.index, self.group);\n      stop();\n    }\n  }\n\n  function stop() {\n    self.state = ENDED;\n    self.timer.stop();\n    delete schedules[id];\n    for (var i in schedules) return; // eslint-disable-line no-unused-vars\n    delete node.__transition;\n  }\n}\n","import {STARTING, ENDING, ENDED} from \"./transition/schedule.js\";\n\nexport default function(node, name) {\n  var schedules = node.__transition,\n      schedule,\n      active,\n      empty = true,\n      i;\n\n  if (!schedules) return;\n\n  name = name == null ? null : name + \"\";\n\n  for (i in schedules) {\n    if ((schedule = schedules[i]).name !== name) { empty = false; continue; }\n    active = schedule.state > STARTING && schedule.state < ENDING;\n    schedule.state = ENDED;\n    schedule.timer.stop();\n    schedule.on.call(active ? \"interrupt\" : \"cancel\", node, node.__data__, schedule.index, schedule.group);\n    delete schedules[i];\n  }\n\n  if (empty) delete node.__transition;\n}\n","import decompose, {identity} from \"./decompose.js\";\n\nvar cssNode,\n    cssRoot,\n    cssView,\n    svgNode;\n\nexport function parseCss(value) {\n  if (value === \"none\") return identity;\n  if (!cssNode) cssNode = document.createElement(\"DIV\"), cssRoot = document.documentElement, cssView = document.defaultView;\n  cssNode.style.transform = value;\n  value = cssView.getComputedStyle(cssRoot.appendChild(cssNode), null).getPropertyValue(\"transform\");\n  cssRoot.removeChild(cssNode);\n  value = value.slice(7, -1).split(\",\");\n  return decompose(+value[0], +value[1], +value[2], +value[3], +value[4], +value[5]);\n}\n\nexport function parseSvg(value) {\n  if (value == null) return identity;\n  if (!svgNode) svgNode = document.createElementNS(\"http://www.w3.org/2000/svg\", \"g\");\n  svgNode.setAttribute(\"transform\", value);\n  if (!(value = svgNode.transform.baseVal.consolidate())) return identity;\n  value = value.matrix;\n  return decompose(value.a, value.b, value.c, value.d, value.e, value.f);\n}\n","var degrees = 180 / Math.PI;\n\nexport var identity = {\n  translateX: 0,\n  translateY: 0,\n  rotate: 0,\n  skewX: 0,\n  scaleX: 1,\n  scaleY: 1\n};\n\nexport default function(a, b, c, d, e, f) {\n  var scaleX, scaleY, skewX;\n  if (scaleX = Math.sqrt(a * a + b * b)) a /= scaleX, b /= scaleX;\n  if (skewX = a * c + b * d) c -= a * skewX, d -= b * skewX;\n  if (scaleY = Math.sqrt(c * c + d * d)) c /= scaleY, d /= scaleY, skewX /= scaleY;\n  if (a * d < b * c) a = -a, b = -b, skewX = -skewX, scaleX = -scaleX;\n  return {\n    translateX: e,\n    translateY: f,\n    rotate: Math.atan2(b, a) * degrees,\n    skewX: Math.atan(skewX) * degrees,\n    scaleX: scaleX,\n    scaleY: scaleY\n  };\n}\n","import number from \"../number.js\";\nimport {parseCss, parseSvg} from \"./parse.js\";\n\nfunction interpolateTransform(parse, pxComma, pxParen, degParen) {\n\n  function pop(s) {\n    return s.length ? s.pop() + \" \" : \"\";\n  }\n\n  function translate(xa, ya, xb, yb, s, q) {\n    if (xa !== xb || ya !== yb) {\n      var i = s.push(\"translate(\", null, pxComma, null, pxParen);\n      q.push({i: i - 4, x: number(xa, xb)}, {i: i - 2, x: number(ya, yb)});\n    } else if (xb || yb) {\n      s.push(\"translate(\" + xb + pxComma + yb + pxParen);\n    }\n  }\n\n  function rotate(a, b, s, q) {\n    if (a !== b) {\n      if (a - b > 180) b += 360; else if (b - a > 180) a += 360; // shortest path\n      q.push({i: s.push(pop(s) + \"rotate(\", null, degParen) - 2, x: number(a, b)});\n    } else if (b) {\n      s.push(pop(s) + \"rotate(\" + b + degParen);\n    }\n  }\n\n  function skewX(a, b, s, q) {\n    if (a !== b) {\n      q.push({i: s.push(pop(s) + \"skewX(\", null, degParen) - 2, x: number(a, b)});\n    } else if (b) {\n      s.push(pop(s) + \"skewX(\" + b + degParen);\n    }\n  }\n\n  function scale(xa, ya, xb, yb, s, q) {\n    if (xa !== xb || ya !== yb) {\n      var i = s.push(pop(s) + \"scale(\", null, \",\", null, \")\");\n      q.push({i: i - 4, x: number(xa, xb)}, {i: i - 2, x: number(ya, yb)});\n    } else if (xb !== 1 || yb !== 1) {\n      s.push(pop(s) + \"scale(\" + xb + \",\" + yb + \")\");\n    }\n  }\n\n  return function(a, b) {\n    var s = [], // string constants and placeholders\n        q = []; // number interpolators\n    a = parse(a), b = parse(b);\n    translate(a.translateX, a.translateY, b.translateX, b.translateY, s, q);\n    rotate(a.rotate, b.rotate, s, q);\n    skewX(a.skewX, b.skewX, s, q);\n    scale(a.scaleX, a.scaleY, b.scaleX, b.scaleY, s, q);\n    a = b = null; // gc\n    return function(t) {\n      var i = -1, n = q.length, o;\n      while (++i < n) s[(o = q[i]).i] = o.x(t);\n      return s.join(\"\");\n    };\n  };\n}\n\nexport var interpolateTransformCss = interpolateTransform(parseCss, \"px, \", \"px)\", \"deg)\");\nexport var interpolateTransformSvg = interpolateTransform(parseSvg, \", \", \")\", \")\");\n","import {get, set} from \"./schedule.js\";\n\nfunction tweenRemove(id, name) {\n  var tween0, tween1;\n  return function() {\n    var schedule = set(this, id),\n        tween = schedule.tween;\n\n    // If this node shared tween with the previous node,\n    // just assign the updated shared tween and we’re done!\n    // Otherwise, copy-on-write.\n    if (tween !== tween0) {\n      tween1 = tween0 = tween;\n      for (var i = 0, n = tween1.length; i < n; ++i) {\n        if (tween1[i].name === name) {\n          tween1 = tween1.slice();\n          tween1.splice(i, 1);\n          break;\n        }\n      }\n    }\n\n    schedule.tween = tween1;\n  };\n}\n\nfunction tweenFunction(id, name, value) {\n  var tween0, tween1;\n  if (typeof value !== \"function\") throw new Error;\n  return function() {\n    var schedule = set(this, id),\n        tween = schedule.tween;\n\n    // If this node shared tween with the previous node,\n    // just assign the updated shared tween and we’re done!\n    // Otherwise, copy-on-write.\n    if (tween !== tween0) {\n      tween1 = (tween0 = tween).slice();\n      for (var t = {name: name, value: value}, i = 0, n = tween1.length; i < n; ++i) {\n        if (tween1[i].name === name) {\n          tween1[i] = t;\n          break;\n        }\n      }\n      if (i === n) tween1.push(t);\n    }\n\n    schedule.tween = tween1;\n  };\n}\n\nexport default function(name, value) {\n  var id = this._id;\n\n  name += \"\";\n\n  if (arguments.length < 2) {\n    var tween = get(this.node(), id).tween;\n    for (var i = 0, n = tween.length, t; i < n; ++i) {\n      if ((t = tween[i]).name === name) {\n        return t.value;\n      }\n    }\n    return null;\n  }\n\n  return this.each((value == null ? tweenRemove : tweenFunction)(id, name, value));\n}\n\nexport function tweenValue(transition, name, value) {\n  var id = transition._id;\n\n  transition.each(function() {\n    var schedule = set(this, id);\n    (schedule.value || (schedule.value = {}))[name] = value.apply(this, arguments);\n  });\n\n  return function(node) {\n    return get(node, id).value[name];\n  };\n}\n","import {color} from \"d3-color\";\nimport {interpolateNumber, interpolateRgb, interpolateString} from \"d3-interpolate\";\n\nexport default function(a, b) {\n  var c;\n  return (typeof b === \"number\" ? interpolateNumber\n      : b instanceof color ? interpolateRgb\n      : (c = color(b)) ? (b = c, interpolateRgb)\n      : interpolateString)(a, b);\n}\n","import {interpolateTransformSvg as interpolateTransform} from \"d3-interpolate\";\nimport {namespace} from \"d3-selection\";\nimport {tweenValue} from \"./tween.js\";\nimport interpolate from \"./interpolate.js\";\n\nfunction attrRemove(name) {\n  return function() {\n    this.removeAttribute(name);\n  };\n}\n\nfunction attrRemoveNS(fullname) {\n  return function() {\n    this.removeAttributeNS(fullname.space, fullname.local);\n  };\n}\n\nfunction attrConstant(name, interpolate, value1) {\n  var string00,\n      string1 = value1 + \"\",\n      interpolate0;\n  return function() {\n    var string0 = this.getAttribute(name);\n    return string0 === string1 ? null\n        : string0 === string00 ? interpolate0\n        : interpolate0 = interpolate(string00 = string0, value1);\n  };\n}\n\nfunction attrConstantNS(fullname, interpolate, value1) {\n  var string00,\n      string1 = value1 + \"\",\n      interpolate0;\n  return function() {\n    var string0 = this.getAttributeNS(fullname.space, fullname.local);\n    return string0 === string1 ? null\n        : string0 === string00 ? interpolate0\n        : interpolate0 = interpolate(string00 = string0, value1);\n  };\n}\n\nfunction attrFunction(name, interpolate, value) {\n  var string00,\n      string10,\n      interpolate0;\n  return function() {\n    var string0, value1 = value(this), string1;\n    if (value1 == null) return void this.removeAttribute(name);\n    string0 = this.getAttribute(name);\n    string1 = value1 + \"\";\n    return string0 === string1 ? null\n        : string0 === string00 && string1 === string10 ? interpolate0\n        : (string10 = string1, interpolate0 = interpolate(string00 = string0, value1));\n  };\n}\n\nfunction attrFunctionNS(fullname, interpolate, value) {\n  var string00,\n      string10,\n      interpolate0;\n  return function() {\n    var string0, value1 = value(this), string1;\n    if (value1 == null) return void this.removeAttributeNS(fullname.space, fullname.local);\n    string0 = this.getAttributeNS(fullname.space, fullname.local);\n    string1 = value1 + \"\";\n    return string0 === string1 ? null\n        : string0 === string00 && string1 === string10 ? interpolate0\n        : (string10 = string1, interpolate0 = interpolate(string00 = string0, value1));\n  };\n}\n\nexport default function(name, value) {\n  var fullname = namespace(name), i = fullname === \"transform\" ? interpolateTransform : interpolate;\n  return this.attrTween(name, typeof value === \"function\"\n      ? (fullname.local ? attrFunctionNS : attrFunction)(fullname, i, tweenValue(this, \"attr.\" + name, value))\n      : value == null ? (fullname.local ? attrRemoveNS : attrRemove)(fullname)\n      : (fullname.local ? attrConstantNS : attrConstant)(fullname, i, value));\n}\n","import {namespace} from \"d3-selection\";\n\nfunction attrInterpolate(name, i) {\n  return function(t) {\n    this.setAttribute(name, i.call(this, t));\n  };\n}\n\nfunction attrInterpolateNS(fullname, i) {\n  return function(t) {\n    this.setAttributeNS(fullname.space, fullname.local, i.call(this, t));\n  };\n}\n\nfunction attrTweenNS(fullname, value) {\n  var t0, i0;\n  function tween() {\n    var i = value.apply(this, arguments);\n    if (i !== i0) t0 = (i0 = i) && attrInterpolateNS(fullname, i);\n    return t0;\n  }\n  tween._value = value;\n  return tween;\n}\n\nfunction attrTween(name, value) {\n  var t0, i0;\n  function tween() {\n    var i = value.apply(this, arguments);\n    if (i !== i0) t0 = (i0 = i) && attrInterpolate(name, i);\n    return t0;\n  }\n  tween._value = value;\n  return tween;\n}\n\nexport default function(name, value) {\n  var key = \"attr.\" + name;\n  if (arguments.length < 2) return (key = this.tween(key)) && key._value;\n  if (value == null) return this.tween(key, null);\n  if (typeof value !== \"function\") throw new Error;\n  var fullname = namespace(name);\n  return this.tween(key, (fullname.local ? attrTweenNS : attrTween)(fullname, value));\n}\n","import {get, init} from \"./schedule.js\";\n\nfunction delayFunction(id, value) {\n  return function() {\n    init(this, id).delay = +value.apply(this, arguments);\n  };\n}\n\nfunction delayConstant(id, value) {\n  return value = +value, function() {\n    init(this, id).delay = value;\n  };\n}\n\nexport default function(value) {\n  var id = this._id;\n\n  return arguments.length\n      ? this.each((typeof value === \"function\"\n          ? delayFunction\n          : delayConstant)(id, value))\n      : get(this.node(), id).delay;\n}\n","import {get, set} from \"./schedule.js\";\n\nfunction durationFunction(id, value) {\n  return function() {\n    set(this, id).duration = +value.apply(this, arguments);\n  };\n}\n\nfunction durationConstant(id, value) {\n  return value = +value, function() {\n    set(this, id).duration = value;\n  };\n}\n\nexport default function(value) {\n  var id = this._id;\n\n  return arguments.length\n      ? this.each((typeof value === \"function\"\n          ? durationFunction\n          : durationConstant)(id, value))\n      : get(this.node(), id).duration;\n}\n","import {get, set} from \"./schedule.js\";\n\nfunction easeConstant(id, value) {\n  if (typeof value !== \"function\") throw new Error;\n  return function() {\n    set(this, id).ease = value;\n  };\n}\n\nexport default function(value) {\n  var id = this._id;\n\n  return arguments.length\n      ? this.each(easeConstant(id, value))\n      : get(this.node(), id).ease;\n}\n","import {get, set, init} from \"./schedule.js\";\n\nfunction start(name) {\n  return (name + \"\").trim().split(/^|\\s+/).every(function(t) {\n    var i = t.indexOf(\".\");\n    if (i >= 0) t = t.slice(0, i);\n    return !t || t === \"start\";\n  });\n}\n\nfunction onFunction(id, name, listener) {\n  var on0, on1, sit = start(name) ? init : set;\n  return function() {\n    var schedule = sit(this, id),\n        on = schedule.on;\n\n    // If this node shared a dispatch with the previous node,\n    // just assign the updated shared dispatch and we’re done!\n    // Otherwise, copy-on-write.\n    if (on !== on0) (on1 = (on0 = on).copy()).on(name, listener);\n\n    schedule.on = on1;\n  };\n}\n\nexport default function(name, listener) {\n  var id = this._id;\n\n  return arguments.length < 2\n      ? get(this.node(), id).on.on(name)\n      : this.each(onFunction(id, name, listener));\n}\n","function removeFunction(id) {\n  return function() {\n    var parent = this.parentNode;\n    for (var i in this.__transition) if (+i !== id) return;\n    if (parent) parent.removeChild(this);\n  };\n}\n\nexport default function() {\n  return this.on(\"end.remove\", removeFunction(this._id));\n}\n","import {selection} from \"d3-selection\";\n\nvar Selection = selection.prototype.constructor;\n\nexport default function() {\n  return new Selection(this._groups, this._parents);\n}\n","import {interpolateTransformCss as interpolateTransform} from \"d3-interpolate\";\nimport {style} from \"d3-selection\";\nimport {set} from \"./schedule.js\";\nimport {tweenValue} from \"./tween.js\";\nimport interpolate from \"./interpolate.js\";\n\nfunction styleNull(name, interpolate) {\n  var string00,\n      string10,\n      interpolate0;\n  return function() {\n    var string0 = style(this, name),\n        string1 = (this.style.removeProperty(name), style(this, name));\n    return string0 === string1 ? null\n        : string0 === string00 && string1 === string10 ? interpolate0\n        : interpolate0 = interpolate(string00 = string0, string10 = string1);\n  };\n}\n\nfunction styleRemove(name) {\n  return function() {\n    this.style.removeProperty(name);\n  };\n}\n\nfunction styleConstant(name, interpolate, value1) {\n  var string00,\n      string1 = value1 + \"\",\n      interpolate0;\n  return function() {\n    var string0 = style(this, name);\n    return string0 === string1 ? null\n        : string0 === string00 ? interpolate0\n        : interpolate0 = interpolate(string00 = string0, value1);\n  };\n}\n\nfunction styleFunction(name, interpolate, value) {\n  var string00,\n      string10,\n      interpolate0;\n  return function() {\n    var string0 = style(this, name),\n        value1 = value(this),\n        string1 = value1 + \"\";\n    if (value1 == null) string1 = value1 = (this.style.removeProperty(name), style(this, name));\n    return string0 === string1 ? null\n        : string0 === string00 && string1 === string10 ? interpolate0\n        : (string10 = string1, interpolate0 = interpolate(string00 = string0, value1));\n  };\n}\n\nfunction styleMaybeRemove(id, name) {\n  var on0, on1, listener0, key = \"style.\" + name, event = \"end.\" + key, remove;\n  return function() {\n    var schedule = set(this, id),\n        on = schedule.on,\n        listener = schedule.value[key] == null ? remove || (remove = styleRemove(name)) : undefined;\n\n    // If this node shared a dispatch with the previous node,\n    // just assign the updated shared dispatch and we’re done!\n    // Otherwise, copy-on-write.\n    if (on !== on0 || listener0 !== listener) (on1 = (on0 = on).copy()).on(event, listener0 = listener);\n\n    schedule.on = on1;\n  };\n}\n\nexport default function(name, value, priority) {\n  var i = (name += \"\") === \"transform\" ? interpolateTransform : interpolate;\n  return value == null ? this\n      .styleTween(name, styleNull(name, i))\n      .on(\"end.style.\" + name, styleRemove(name))\n    : typeof value === \"function\" ? this\n      .styleTween(name, styleFunction(name, i, tweenValue(this, \"style.\" + name, value)))\n      .each(styleMaybeRemove(this._id, name))\n    : this\n      .styleTween(name, styleConstant(name, i, value), priority)\n      .on(\"end.style.\" + name, null);\n}\n","function styleInterpolate(name, i, priority) {\n  return function(t) {\n    this.style.setProperty(name, i.call(this, t), priority);\n  };\n}\n\nfunction styleTween(name, value, priority) {\n  var t, i0;\n  function tween() {\n    var i = value.apply(this, arguments);\n    if (i !== i0) t = (i0 = i) && styleInterpolate(name, i, priority);\n    return t;\n  }\n  tween._value = value;\n  return tween;\n}\n\nexport default function(name, value, priority) {\n  var key = \"style.\" + (name += \"\");\n  if (arguments.length < 2) return (key = this.tween(key)) && key._value;\n  if (value == null) return this.tween(key, null);\n  if (typeof value !== \"function\") throw new Error;\n  return this.tween(key, styleTween(name, value, priority == null ? \"\" : priority));\n}\n","function textInterpolate(i) {\n  return function(t) {\n    this.textContent = i.call(this, t);\n  };\n}\n\nfunction textTween(value) {\n  var t0, i0;\n  function tween() {\n    var i = value.apply(this, arguments);\n    if (i !== i0) t0 = (i0 = i) && textInterpolate(i);\n    return t0;\n  }\n  tween._value = value;\n  return tween;\n}\n\nexport default function(value) {\n  var key = \"text\";\n  if (arguments.length < 1) return (key = this.tween(key)) && key._value;\n  if (value == null) return this.tween(key, null);\n  if (typeof value !== \"function\") throw new Error;\n  return this.tween(key, textTween(value));\n}\n","import {selection} from \"d3-selection\";\nimport transition_attr from \"./attr.js\";\nimport transition_attrTween from \"./attrTween.js\";\nimport transition_delay from \"./delay.js\";\nimport transition_duration from \"./duration.js\";\nimport transition_ease from \"./ease.js\";\nimport transition_filter from \"./filter.js\";\nimport transition_merge from \"./merge.js\";\nimport transition_on from \"./on.js\";\nimport transition_remove from \"./remove.js\";\nimport transition_select from \"./select.js\";\nimport transition_selectAll from \"./selectAll.js\";\nimport transition_selection from \"./selection.js\";\nimport transition_style from \"./style.js\";\nimport transition_styleTween from \"./styleTween.js\";\nimport transition_text from \"./text.js\";\nimport transition_textTween from \"./textTween.js\";\nimport transition_transition from \"./transition.js\";\nimport transition_tween from \"./tween.js\";\nimport transition_end from \"./end.js\";\n\nvar id = 0;\n\nexport function Transition(groups, parents, name, id) {\n  this._groups = groups;\n  this._parents = parents;\n  this._name = name;\n  this._id = id;\n}\n\nexport default function transition(name) {\n  return selection().transition(name);\n}\n\nexport function newId() {\n  return ++id;\n}\n\nvar selection_prototype = selection.prototype;\n\nTransition.prototype = transition.prototype = {\n  constructor: Transition,\n  select: transition_select,\n  selectAll: transition_selectAll,\n  filter: transition_filter,\n  merge: transition_merge,\n  selection: transition_selection,\n  transition: transition_transition,\n  call: selection_prototype.call,\n  nodes: selection_prototype.nodes,\n  node: selection_prototype.node,\n  size: selection_prototype.size,\n  empty: selection_prototype.empty,\n  each: selection_prototype.each,\n  on: transition_on,\n  attr: transition_attr,\n  attrTween: transition_attrTween,\n  style: transition_style,\n  styleTween: transition_styleTween,\n  text: transition_text,\n  textTween: transition_textTween,\n  remove: transition_remove,\n  tween: transition_tween,\n  delay: transition_delay,\n  duration: transition_duration,\n  ease: transition_ease,\n  end: transition_end\n};\n","import {selector} from \"d3-selection\";\nimport {Transition} from \"./index.js\";\nimport schedule, {get} from \"./schedule.js\";\n\nexport default function(select) {\n  var name = this._name,\n      id = this._id;\n\n  if (typeof select !== \"function\") select = selector(select);\n\n  for (var groups = this._groups, m = groups.length, subgroups = new Array(m), j = 0; j < m; ++j) {\n    for (var group = groups[j], n = group.length, subgroup = subgroups[j] = new Array(n), node, subnode, i = 0; i < n; ++i) {\n      if ((node = group[i]) && (subnode = select.call(node, node.__data__, i, group))) {\n        if (\"__data__\" in node) subnode.__data__ = node.__data__;\n        subgroup[i] = subnode;\n        schedule(subgroup[i], name, id, i, subgroup, get(node, id));\n      }\n    }\n  }\n\n  return new Transition(subgroups, this._parents, name, id);\n}\n","import {selectorAll} from \"d3-selection\";\nimport {Transition} from \"./index.js\";\nimport schedule, {get} from \"./schedule.js\";\n\nexport default function(select) {\n  var name = this._name,\n      id = this._id;\n\n  if (typeof select !== \"function\") select = selectorAll(select);\n\n  for (var groups = this._groups, m = groups.length, subgroups = [], parents = [], j = 0; j < m; ++j) {\n    for (var group = groups[j], n = group.length, node, i = 0; i < n; ++i) {\n      if (node = group[i]) {\n        for (var children = select.call(node, node.__data__, i, group), child, inherit = get(node, id), k = 0, l = children.length; k < l; ++k) {\n          if (child = children[k]) {\n            schedule(child, name, id, k, children, inherit);\n          }\n        }\n        subgroups.push(children);\n        parents.push(node);\n      }\n    }\n  }\n\n  return new Transition(subgroups, parents, name, id);\n}\n","import {matcher} from \"d3-selection\";\nimport {Transition} from \"./index.js\";\n\nexport default function(match) {\n  if (typeof match !== \"function\") match = matcher(match);\n\n  for (var groups = this._groups, m = groups.length, subgroups = new Array(m), j = 0; j < m; ++j) {\n    for (var group = groups[j], n = group.length, subgroup = subgroups[j] = [], node, i = 0; i < n; ++i) {\n      if ((node = group[i]) && match.call(node, node.__data__, i, group)) {\n        subgroup.push(node);\n      }\n    }\n  }\n\n  return new Transition(subgroups, this._parents, this._name, this._id);\n}\n","import {Transition} from \"./index.js\";\n\nexport default function(transition) {\n  if (transition._id !== this._id) throw new Error;\n\n  for (var groups0 = this._groups, groups1 = transition._groups, m0 = groups0.length, m1 = groups1.length, m = Math.min(m0, m1), merges = new Array(m0), j = 0; j < m; ++j) {\n    for (var group0 = groups0[j], group1 = groups1[j], n = group0.length, merge = merges[j] = new Array(n), node, i = 0; i < n; ++i) {\n      if (node = group0[i] || group1[i]) {\n        merge[i] = node;\n      }\n    }\n  }\n\n  for (; j < m0; ++j) {\n    merges[j] = groups0[j];\n  }\n\n  return new Transition(merges, this._parents, this._name, this._id);\n}\n","import {Transition, newId} from \"./index.js\";\nimport schedule, {get} from \"./schedule.js\";\n\nexport default function() {\n  var name = this._name,\n      id0 = this._id,\n      id1 = newId();\n\n  for (var groups = this._groups, m = groups.length, j = 0; j < m; ++j) {\n    for (var group = groups[j], n = group.length, node, i = 0; i < n; ++i) {\n      if (node = group[i]) {\n        var inherit = get(node, id0);\n        schedule(node, name, id1, i, group, {\n          time: inherit.time + inherit.delay + inherit.duration,\n          delay: 0,\n          duration: inherit.duration,\n          ease: inherit.ease\n        });\n      }\n    }\n  }\n\n  return new Transition(groups, this._parents, name, id1);\n}\n","import {tweenValue} from \"./tween.js\";\n\nfunction textConstant(value) {\n  return function() {\n    this.textContent = value;\n  };\n}\n\nfunction textFunction(value) {\n  return function() {\n    var value1 = value(this);\n    this.textContent = value1 == null ? \"\" : value1;\n  };\n}\n\nexport default function(value) {\n  return this.tween(\"text\", typeof value === \"function\"\n      ? textFunction(tweenValue(this, \"text\", value))\n      : textConstant(value == null ? \"\" : value + \"\"));\n}\n","import {set} from \"./schedule.js\";\n\nexport default function() {\n  var on0, on1, that = this, id = that._id, size = that.size();\n  return new Promise(function(resolve, reject) {\n    var cancel = {value: reject},\n        end = {value: function() { if (--size === 0) resolve(); }};\n\n    that.each(function() {\n      var schedule = set(this, id),\n          on = schedule.on;\n\n      // If this node shared a dispatch with the previous node,\n      // just assign the updated shared dispatch and we’re done!\n      // Otherwise, copy-on-write.\n      if (on !== on0) {\n        on1 = (on0 = on).copy();\n        on1._.cancel.push(cancel);\n        on1._.interrupt.push(cancel);\n        on1._.end.push(end);\n      }\n\n      schedule.on = on1;\n    });\n  });\n}\n","import {Transition, newId} from \"../transition/index.js\";\nimport schedule from \"../transition/schedule.js\";\nimport {easeCubicInOut} from \"d3-ease\";\nimport {now} from \"d3-timer\";\n\nvar defaultTiming = {\n  time: null, // Set on use.\n  delay: 0,\n  duration: 250,\n  ease: easeCubicInOut\n};\n\nfunction inherit(node, id) {\n  var timing;\n  while (!(timing = node.__transition) || !(timing = timing[id])) {\n    if (!(node = node.parentNode)) {\n      return defaultTiming.time = now(), defaultTiming;\n    }\n  }\n  return timing;\n}\n\nexport default function(name) {\n  var id,\n      timing;\n\n  if (name instanceof Transition) {\n    id = name._id, name = name._name;\n  } else {\n    id = newId(), (timing = defaultTiming).time = now(), name = name == null ? null : name + \"\";\n  }\n\n  for (var groups = this._groups, m = groups.length, j = 0; j < m; ++j) {\n    for (var group = groups[j], n = group.length, node, i = 0; i < n; ++i) {\n      if (node = group[i]) {\n        schedule(node, name, id, i, group, timing || inherit(node, id));\n      }\n    }\n  }\n\n  return new Transition(groups, this._parents, name, id);\n}\n","export function cubicIn(t) {\n  return t * t * t;\n}\n\nexport function cubicOut(t) {\n  return --t * t * t + 1;\n}\n\nexport function cubicInOut(t) {\n  return ((t *= 2) <= 1 ? t * t * t : (t -= 2) * t * t + 2) / 2;\n}\n","import {selection} from \"d3-selection\";\nimport selection_interrupt from \"./interrupt.js\";\nimport selection_transition from \"./transition.js\";\n\nselection.prototype.interrupt = selection_interrupt;\nselection.prototype.transition = selection_transition;\n","import interrupt from \"../interrupt.js\";\n\nexport default function(name) {\n  return this.each(function() {\n    interrupt(this, name);\n  });\n}\n","import {Transition} from \"./transition/index.js\";\nimport {SCHEDULED} from \"./transition/schedule.js\";\n\nvar root = [null];\n\nexport default function(node, name) {\n  var schedules = node.__transition,\n      schedule,\n      i;\n\n  if (schedules) {\n    name = name == null ? null : name + \"\";\n    for (i in schedules) {\n      if ((schedule = schedules[i]).state > SCHEDULED && schedule.name === name) {\n        return new Transition([[node]], root, name, +i);\n      }\n    }\n  }\n\n  return null;\n}\n","export default function(x) {\n  return function() {\n    return x;\n  };\n}\n","export default function(target, type, selection) {\n  this.target = target;\n  this.type = type;\n  this.selection = selection;\n}\n","import {event} from \"d3-selection\";\n\nexport function nopropagation() {\n  event.stopImmediatePropagation();\n}\n\nexport default function() {\n  event.preventDefault();\n  event.stopImmediatePropagation();\n}\n","import {dispatch} from \"d3-dispatch\";\nimport {dragDisable, dragEnable} from \"d3-drag\";\nimport {interpolate} from \"d3-interpolate\";\nimport {customEvent, event, touch, mouse, select} from \"d3-selection\";\nimport {interrupt} from \"d3-transition\";\nimport constant from \"./constant.js\";\nimport BrushEvent from \"./event.js\";\nimport noevent, {nopropagation} from \"./noevent.js\";\n\nvar MODE_DRAG = {name: \"drag\"},\n    MODE_SPACE = {name: \"space\"},\n    MODE_HANDLE = {name: \"handle\"},\n    MODE_CENTER = {name: \"center\"};\n\nfunction number1(e) {\n  return [+e[0], +e[1]];\n}\n\nfunction number2(e) {\n  return [number1(e[0]), number1(e[1])];\n}\n\nfunction toucher(identifier) {\n  return function(target) {\n    return touch(target, event.touches, identifier);\n  };\n}\n\nvar X = {\n  name: \"x\",\n  handles: [\"w\", \"e\"].map(type),\n  input: function(x, e) { return x == null ? null : [[+x[0], e[0][1]], [+x[1], e[1][1]]]; },\n  output: function(xy) { return xy && [xy[0][0], xy[1][0]]; }\n};\n\nvar Y = {\n  name: \"y\",\n  handles: [\"n\", \"s\"].map(type),\n  input: function(y, e) { return y == null ? null : [[e[0][0], +y[0]], [e[1][0], +y[1]]]; },\n  output: function(xy) { return xy && [xy[0][1], xy[1][1]]; }\n};\n\nvar XY = {\n  name: \"xy\",\n  handles: [\"n\", \"w\", \"e\", \"s\", \"nw\", \"ne\", \"sw\", \"se\"].map(type),\n  input: function(xy) { return xy == null ? null : number2(xy); },\n  output: function(xy) { return xy; }\n};\n\nvar cursors = {\n  overlay: \"crosshair\",\n  selection: \"move\",\n  n: \"ns-resize\",\n  e: \"ew-resize\",\n  s: \"ns-resize\",\n  w: \"ew-resize\",\n  nw: \"nwse-resize\",\n  ne: \"nesw-resize\",\n  se: \"nwse-resize\",\n  sw: \"nesw-resize\"\n};\n\nvar flipX = {\n  e: \"w\",\n  w: \"e\",\n  nw: \"ne\",\n  ne: \"nw\",\n  se: \"sw\",\n  sw: \"se\"\n};\n\nvar flipY = {\n  n: \"s\",\n  s: \"n\",\n  nw: \"sw\",\n  ne: \"se\",\n  se: \"ne\",\n  sw: \"nw\"\n};\n\nvar signsX = {\n  overlay: +1,\n  selection: +1,\n  n: null,\n  e: +1,\n  s: null,\n  w: -1,\n  nw: -1,\n  ne: +1,\n  se: +1,\n  sw: -1\n};\n\nvar signsY = {\n  overlay: +1,\n  selection: +1,\n  n: -1,\n  e: null,\n  s: +1,\n  w: null,\n  nw: -1,\n  ne: -1,\n  se: +1,\n  sw: +1\n};\n\nfunction type(t) {\n  return {type: t};\n}\n\n// Ignore right-click, since that should open the context menu.\nfunction defaultFilter() {\n  return !event.ctrlKey && !event.button;\n}\n\nfunction defaultExtent() {\n  var svg = this.ownerSVGElement || this;\n  if (svg.hasAttribute(\"viewBox\")) {\n    svg = svg.viewBox.baseVal;\n    return [[svg.x, svg.y], [svg.x + svg.width, svg.y + svg.height]];\n  }\n  return [[0, 0], [svg.width.baseVal.value, svg.height.baseVal.value]];\n}\n\nfunction defaultTouchable() {\n  return navigator.maxTouchPoints || (\"ontouchstart\" in this);\n}\n\n// Like d3.local, but with the name “__brush” rather than auto-generated.\nfunction local(node) {\n  while (!node.__brush) if (!(node = node.parentNode)) return;\n  return node.__brush;\n}\n\nfunction empty(extent) {\n  return extent[0][0] === extent[1][0]\n      || extent[0][1] === extent[1][1];\n}\n\nexport function brushSelection(node) {\n  var state = node.__brush;\n  return state ? state.dim.output(state.selection) : null;\n}\n\nexport function brushX() {\n  return brush(X);\n}\n\nexport function brushY() {\n  return brush(Y);\n}\n\nexport default function() {\n  return brush(XY);\n}\n\nfunction brush(dim) {\n  var extent = defaultExtent,\n      filter = defaultFilter,\n      touchable = defaultTouchable,\n      keys = true,\n      listeners = dispatch(\"start\", \"brush\", \"end\"),\n      handleSize = 6,\n      touchending;\n\n  function brush(group) {\n    var overlay = group\n        .property(\"__brush\", initialize)\n      .selectAll(\".overlay\")\n      .data([type(\"overlay\")]);\n\n    overlay.enter().append(\"rect\")\n        .attr(\"class\", \"overlay\")\n        .attr(\"pointer-events\", \"all\")\n        .attr(\"cursor\", cursors.overlay)\n      .merge(overlay)\n        .each(function() {\n          var extent = local(this).extent;\n          select(this)\n              .attr(\"x\", extent[0][0])\n              .attr(\"y\", extent[0][1])\n              .attr(\"width\", extent[1][0] - extent[0][0])\n              .attr(\"height\", extent[1][1] - extent[0][1]);\n        });\n\n    group.selectAll(\".selection\")\n      .data([type(\"selection\")])\n      .enter().append(\"rect\")\n        .attr(\"class\", \"selection\")\n        .attr(\"cursor\", cursors.selection)\n        .attr(\"fill\", \"#777\")\n        .attr(\"fill-opacity\", 0.3)\n        .attr(\"stroke\", \"#fff\")\n        .attr(\"shape-rendering\", \"crispEdges\");\n\n    var handle = group.selectAll(\".handle\")\n      .data(dim.handles, function(d) { return d.type; });\n\n    handle.exit().remove();\n\n    handle.enter().append(\"rect\")\n        .attr(\"class\", function(d) { return \"handle handle--\" + d.type; })\n        .attr(\"cursor\", function(d) { return cursors[d.type]; });\n\n    group\n        .each(redraw)\n        .attr(\"fill\", \"none\")\n        .attr(\"pointer-events\", \"all\")\n        .on(\"mousedown.brush\", started)\n      .filter(touchable)\n        .on(\"touchstart.brush\", started)\n        .on(\"touchmove.brush\", touchmoved)\n        .on(\"touchend.brush touchcancel.brush\", touchended)\n        .style(\"touch-action\", \"none\")\n        .style(\"-webkit-tap-highlight-color\", \"rgba(0,0,0,0)\");\n  }\n\n  brush.move = function(group, selection) {\n    if (group.selection) {\n      group\n          .on(\"start.brush\", function() { emitter(this, arguments).beforestart().start(); })\n          .on(\"interrupt.brush end.brush\", function() { emitter(this, arguments).end(); })\n          .tween(\"brush\", function() {\n            var that = this,\n                state = that.__brush,\n                emit = emitter(that, arguments),\n                selection0 = state.selection,\n                selection1 = dim.input(typeof selection === \"function\" ? selection.apply(this, arguments) : selection, state.extent),\n                i = interpolate(selection0, selection1);\n\n            function tween(t) {\n              state.selection = t === 1 && selection1 === null ? null : i(t);\n              redraw.call(that);\n              emit.brush();\n            }\n\n            return selection0 !== null && selection1 !== null ? tween : tween(1);\n          });\n    } else {\n      group\n          .each(function() {\n            var that = this,\n                args = arguments,\n                state = that.__brush,\n                selection1 = dim.input(typeof selection === \"function\" ? selection.apply(that, args) : selection, state.extent),\n                emit = emitter(that, args).beforestart();\n\n            interrupt(that);\n            state.selection = selection1 === null ? null : selection1;\n            redraw.call(that);\n            emit.start().brush().end();\n          });\n    }\n  };\n\n  brush.clear = function(group) {\n    brush.move(group, null);\n  };\n\n  function redraw() {\n    var group = select(this),\n        selection = local(this).selection;\n\n    if (selection) {\n      group.selectAll(\".selection\")\n          .style(\"display\", null)\n          .attr(\"x\", selection[0][0])\n          .attr(\"y\", selection[0][1])\n          .attr(\"width\", selection[1][0] - selection[0][0])\n          .attr(\"height\", selection[1][1] - selection[0][1]);\n\n      group.selectAll(\".handle\")\n          .style(\"display\", null)\n          .attr(\"x\", function(d) { return d.type[d.type.length - 1] === \"e\" ? selection[1][0] - handleSize / 2 : selection[0][0] - handleSize / 2; })\n          .attr(\"y\", function(d) { return d.type[0] === \"s\" ? selection[1][1] - handleSize / 2 : selection[0][1] - handleSize / 2; })\n          .attr(\"width\", function(d) { return d.type === \"n\" || d.type === \"s\" ? selection[1][0] - selection[0][0] + handleSize : handleSize; })\n          .attr(\"height\", function(d) { return d.type === \"e\" || d.type === \"w\" ? selection[1][1] - selection[0][1] + handleSize : handleSize; });\n    }\n\n    else {\n      group.selectAll(\".selection,.handle\")\n          .style(\"display\", \"none\")\n          .attr(\"x\", null)\n          .attr(\"y\", null)\n          .attr(\"width\", null)\n          .attr(\"height\", null);\n    }\n  }\n\n  function emitter(that, args, clean) {\n    return (!clean && that.__brush.emitter) || new Emitter(that, args);\n  }\n\n  function Emitter(that, args) {\n    this.that = that;\n    this.args = args;\n    this.state = that.__brush;\n    this.active = 0;\n  }\n\n  Emitter.prototype = {\n    beforestart: function() {\n      if (++this.active === 1) this.state.emitter = this, this.starting = true;\n      return this;\n    },\n    start: function() {\n      if (this.starting) this.starting = false, this.emit(\"start\");\n      else this.emit(\"brush\");\n      return this;\n    },\n    brush: function() {\n      this.emit(\"brush\");\n      return this;\n    },\n    end: function() {\n      if (--this.active === 0) delete this.state.emitter, this.emit(\"end\");\n      return this;\n    },\n    emit: function(type) {\n      customEvent(new BrushEvent(brush, type, dim.output(this.state.selection)), listeners.apply, listeners, [type, this.that, this.args]);\n    }\n  };\n\n  function started() {\n    if (touchending && !event.touches) return;\n    if (!filter.apply(this, arguments)) return;\n\n    var that = this,\n        type = event.target.__data__.type,\n        mode = (keys && event.metaKey ? type = \"overlay\" : type) === \"selection\" ? MODE_DRAG : (keys && event.altKey ? MODE_CENTER : MODE_HANDLE),\n        signX = dim === Y ? null : signsX[type],\n        signY = dim === X ? null : signsY[type],\n        state = local(that),\n        extent = state.extent,\n        selection = state.selection,\n        W = extent[0][0], w0, w1,\n        N = extent[0][1], n0, n1,\n        E = extent[1][0], e0, e1,\n        S = extent[1][1], s0, s1,\n        dx = 0,\n        dy = 0,\n        moving,\n        shifting = signX && signY && keys && event.shiftKey,\n        lockX,\n        lockY,\n        pointer = event.touches ? toucher(event.changedTouches[0].identifier) : mouse,\n        point0 = pointer(that),\n        point = point0,\n        emit = emitter(that, arguments, true).beforestart();\n\n    if (type === \"overlay\") {\n      if (selection) moving = true;\n      state.selection = selection = [\n        [w0 = dim === Y ? W : point0[0], n0 = dim === X ? N : point0[1]],\n        [e0 = dim === Y ? E : w0, s0 = dim === X ? S : n0]\n      ];\n    } else {\n      w0 = selection[0][0];\n      n0 = selection[0][1];\n      e0 = selection[1][0];\n      s0 = selection[1][1];\n    }\n\n    w1 = w0;\n    n1 = n0;\n    e1 = e0;\n    s1 = s0;\n\n    var group = select(that)\n        .attr(\"pointer-events\", \"none\");\n\n    var overlay = group.selectAll(\".overlay\")\n        .attr(\"cursor\", cursors[type]);\n\n    if (event.touches) {\n      emit.moved = moved;\n      emit.ended = ended;\n    } else {\n      var view = select(event.view)\n          .on(\"mousemove.brush\", moved, true)\n          .on(\"mouseup.brush\", ended, true);\n      if (keys) view\n          .on(\"keydown.brush\", keydowned, true)\n          .on(\"keyup.brush\", keyupped, true)\n\n      dragDisable(event.view);\n    }\n\n    nopropagation();\n    interrupt(that);\n    redraw.call(that);\n    emit.start();\n\n    function moved() {\n      var point1 = pointer(that);\n      if (shifting && !lockX && !lockY) {\n        if (Math.abs(point1[0] - point[0]) > Math.abs(point1[1] - point[1])) lockY = true;\n        else lockX = true;\n      }\n      point = point1;\n      moving = true;\n      noevent();\n      move();\n    }\n\n    function move() {\n      var t;\n\n      dx = point[0] - point0[0];\n      dy = point[1] - point0[1];\n\n      switch (mode) {\n        case MODE_SPACE:\n        case MODE_DRAG: {\n          if (signX) dx = Math.max(W - w0, Math.min(E - e0, dx)), w1 = w0 + dx, e1 = e0 + dx;\n          if (signY) dy = Math.max(N - n0, Math.min(S - s0, dy)), n1 = n0 + dy, s1 = s0 + dy;\n          break;\n        }\n        case MODE_HANDLE: {\n          if (signX < 0) dx = Math.max(W - w0, Math.min(E - w0, dx)), w1 = w0 + dx, e1 = e0;\n          else if (signX > 0) dx = Math.max(W - e0, Math.min(E - e0, dx)), w1 = w0, e1 = e0 + dx;\n          if (signY < 0) dy = Math.max(N - n0, Math.min(S - n0, dy)), n1 = n0 + dy, s1 = s0;\n          else if (signY > 0) dy = Math.max(N - s0, Math.min(S - s0, dy)), n1 = n0, s1 = s0 + dy;\n          break;\n        }\n        case MODE_CENTER: {\n          if (signX) w1 = Math.max(W, Math.min(E, w0 - dx * signX)), e1 = Math.max(W, Math.min(E, e0 + dx * signX));\n          if (signY) n1 = Math.max(N, Math.min(S, n0 - dy * signY)), s1 = Math.max(N, Math.min(S, s0 + dy * signY));\n          break;\n        }\n      }\n\n      if (e1 < w1) {\n        signX *= -1;\n        t = w0, w0 = e0, e0 = t;\n        t = w1, w1 = e1, e1 = t;\n        if (type in flipX) overlay.attr(\"cursor\", cursors[type = flipX[type]]);\n      }\n\n      if (s1 < n1) {\n        signY *= -1;\n        t = n0, n0 = s0, s0 = t;\n        t = n1, n1 = s1, s1 = t;\n        if (type in flipY) overlay.attr(\"cursor\", cursors[type = flipY[type]]);\n      }\n\n      if (state.selection) selection = state.selection; // May be set by brush.move!\n      if (lockX) w1 = selection[0][0], e1 = selection[1][0];\n      if (lockY) n1 = selection[0][1], s1 = selection[1][1];\n\n      if (selection[0][0] !== w1\n          || selection[0][1] !== n1\n          || selection[1][0] !== e1\n          || selection[1][1] !== s1) {\n        state.selection = [[w1, n1], [e1, s1]];\n        redraw.call(that);\n        emit.brush();\n      }\n    }\n\n    function ended() {\n      nopropagation();\n      if (event.touches) {\n        if (event.touches.length) return;\n        if (touchending) clearTimeout(touchending);\n        touchending = setTimeout(function() { touchending = null; }, 500); // Ghost clicks are delayed!\n      } else {\n        dragEnable(event.view, moving);\n        view.on(\"keydown.brush keyup.brush mousemove.brush mouseup.brush\", null);\n      }\n      group.attr(\"pointer-events\", \"all\");\n      overlay.attr(\"cursor\", cursors.overlay);\n      if (state.selection) selection = state.selection; // May be set by brush.move (on start)!\n      if (empty(selection)) state.selection = null, redraw.call(that);\n      emit.end();\n    }\n\n    function keydowned() {\n      switch (event.keyCode) {\n        case 16: { // SHIFT\n          shifting = signX && signY;\n          break;\n        }\n        case 18: { // ALT\n          if (mode === MODE_HANDLE) {\n            if (signX) e0 = e1 - dx * signX, w0 = w1 + dx * signX;\n            if (signY) s0 = s1 - dy * signY, n0 = n1 + dy * signY;\n            mode = MODE_CENTER;\n            move();\n          }\n          break;\n        }\n        case 32: { // SPACE; takes priority over ALT\n          if (mode === MODE_HANDLE || mode === MODE_CENTER) {\n            if (signX < 0) e0 = e1 - dx; else if (signX > 0) w0 = w1 - dx;\n            if (signY < 0) s0 = s1 - dy; else if (signY > 0) n0 = n1 - dy;\n            mode = MODE_SPACE;\n            overlay.attr(\"cursor\", cursors.selection);\n            move();\n          }\n          break;\n        }\n        default: return;\n      }\n      noevent();\n    }\n\n    function keyupped() {\n      switch (event.keyCode) {\n        case 16: { // SHIFT\n          if (shifting) {\n            lockX = lockY = shifting = false;\n            move();\n          }\n          break;\n        }\n        case 18: { // ALT\n          if (mode === MODE_CENTER) {\n            if (signX < 0) e0 = e1; else if (signX > 0) w0 = w1;\n            if (signY < 0) s0 = s1; else if (signY > 0) n0 = n1;\n            mode = MODE_HANDLE;\n            move();\n          }\n          break;\n        }\n        case 32: { // SPACE\n          if (mode === MODE_SPACE) {\n            if (event.altKey) {\n              if (signX) e0 = e1 - dx * signX, w0 = w1 + dx * signX;\n              if (signY) s0 = s1 - dy * signY, n0 = n1 + dy * signY;\n              mode = MODE_CENTER;\n            } else {\n              if (signX < 0) e0 = e1; else if (signX > 0) w0 = w1;\n              if (signY < 0) s0 = s1; else if (signY > 0) n0 = n1;\n              mode = MODE_HANDLE;\n            }\n            overlay.attr(\"cursor\", cursors[type]);\n            move();\n          }\n          break;\n        }\n        default: return;\n      }\n      noevent();\n    }\n  }\n\n  function touchmoved() {\n    emitter(this, arguments).moved();\n  }\n\n  function touchended() {\n    emitter(this, arguments).ended();\n  }\n\n  function initialize() {\n    var state = this.__brush || {selection: null};\n    state.extent = number2(extent.apply(this, arguments));\n    state.dim = dim;\n    return state;\n  }\n\n  brush.extent = function(_) {\n    return arguments.length ? (extent = typeof _ === \"function\" ? _ : constant(number2(_)), brush) : extent;\n  };\n\n  brush.filter = function(_) {\n    return arguments.length ? (filter = typeof _ === \"function\" ? _ : constant(!!_), brush) : filter;\n  };\n\n  brush.touchable = function(_) {\n    return arguments.length ? (touchable = typeof _ === \"function\" ? _ : constant(!!_), brush) : touchable;\n  };\n\n  brush.handleSize = function(_) {\n    return arguments.length ? (handleSize = +_, brush) : handleSize;\n  };\n\n  brush.keyModifiers = function(_) {\n    return arguments.length ? (keys = !!_, brush) : keys;\n  };\n\n  brush.on = function() {\n    var value = listeners.on.apply(listeners, arguments);\n    return value === listeners ? brush : value;\n  };\n\n  return brush;\n}\n","import sourceEvent from \"./sourceEvent\";\nimport point from \"./point\";\n\nexport default function(node, touches, identifier) {\n  if (arguments.length < 3) identifier = touches, touches = sourceEvent().changedTouches;\n\n  for (var i = 0, n = touches ? touches.length : 0, touch; i < n; ++i) {\n    if ((touch = touches[i]).identifier === identifier) {\n      return point(node, touch);\n    }\n  }\n\n  return null;\n}\n","// Computes the decimal coefficient and exponent of the specified number x with\n// significant digits p, where x is positive and p is in [1, 21] or undefined.\n// For example, formatDecimal(1.23) returns [\"123\", 0].\nexport default function(x, p) {\n  if ((i = (x = p ? x.toExponential(p - 1) : x.toExponential()).indexOf(\"e\")) < 0) return null; // NaN, ±Infinity\n  var i, coefficient = x.slice(0, i);\n\n  // The string returned by toExponential either has the form \\d\\.\\d+e[-+]\\d+\n  // (e.g., 1.2e+3) or the form \\de[-+]\\d+ (e.g., 1e+3).\n  return [\n    coefficient.length > 1 ? coefficient[0] + coefficient.slice(2) : coefficient,\n    +x.slice(i + 1)\n  ];\n}\n","import formatDecimal from \"./formatDecimal.js\";\n\nexport default function(x) {\n  return x = formatDecimal(Math.abs(x)), x ? x[1] : NaN;\n}\n","// [[fill]align][sign][symbol][0][width][,][.precision][~][type]\nvar re = /^(?:(.)?([<>=^]))?([+\\-( ])?([$#])?(0)?(\\d+)?(,)?(\\.\\d+)?(~)?([a-z%])?$/i;\n\nexport default function formatSpecifier(specifier) {\n  if (!(match = re.exec(specifier))) throw new Error(\"invalid format: \" + specifier);\n  var match;\n  return new FormatSpecifier({\n    fill: match[1],\n    align: match[2],\n    sign: match[3],\n    symbol: match[4],\n    zero: match[5],\n    width: match[6],\n    comma: match[7],\n    precision: match[8] && match[8].slice(1),\n    trim: match[9],\n    type: match[10]\n  });\n}\n\nformatSpecifier.prototype = FormatSpecifier.prototype; // instanceof\n\nexport function FormatSpecifier(specifier) {\n  this.fill = specifier.fill === undefined ? \" \" : specifier.fill + \"\";\n  this.align = specifier.align === undefined ? \">\" : specifier.align + \"\";\n  this.sign = specifier.sign === undefined ? \"-\" : specifier.sign + \"\";\n  this.symbol = specifier.symbol === undefined ? \"\" : specifier.symbol + \"\";\n  this.zero = !!specifier.zero;\n  this.width = specifier.width === undefined ? undefined : +specifier.width;\n  this.comma = !!specifier.comma;\n  this.precision = specifier.precision === undefined ? undefined : +specifier.precision;\n  this.trim = !!specifier.trim;\n  this.type = specifier.type === undefined ? \"\" : specifier.type + \"\";\n}\n\nFormatSpecifier.prototype.toString = function() {\n  return this.fill\n      + this.align\n      + this.sign\n      + this.symbol\n      + (this.zero ? \"0\" : \"\")\n      + (this.width === undefined ? \"\" : Math.max(1, this.width | 0))\n      + (this.comma ? \",\" : \"\")\n      + (this.precision === undefined ? \"\" : \".\" + Math.max(0, this.precision | 0))\n      + (this.trim ? \"~\" : \"\")\n      + this.type;\n};\n","// Trims insignificant zeros, e.g., replaces 1.2000k with 1.2k.\nexport default function(s) {\n  out: for (var n = s.length, i = 1, i0 = -1, i1; i < n; ++i) {\n    switch (s[i]) {\n      case \".\": i0 = i1 = i; break;\n      case \"0\": if (i0 === 0) i0 = i; i1 = i; break;\n      default: if (!+s[i]) break out; if (i0 > 0) i0 = 0; break;\n    }\n  }\n  return i0 > 0 ? s.slice(0, i0) + s.slice(i1 + 1) : s;\n}\n","import formatDecimal from \"./formatDecimal.js\";\n\nexport var prefixExponent;\n\nexport default function(x, p) {\n  var d = formatDecimal(x, p);\n  if (!d) return x + \"\";\n  var coefficient = d[0],\n      exponent = d[1],\n      i = exponent - (prefixExponent = Math.max(-8, Math.min(8, Math.floor(exponent / 3))) * 3) + 1,\n      n = coefficient.length;\n  return i === n ? coefficient\n      : i > n ? coefficient + new Array(i - n + 1).join(\"0\")\n      : i > 0 ? coefficient.slice(0, i) + \".\" + coefficient.slice(i)\n      : \"0.\" + new Array(1 - i).join(\"0\") + formatDecimal(x, Math.max(0, p + i - 1))[0]; // less than 1y!\n}\n","import formatLocale from \"./locale.js\";\n\nvar locale;\nexport var format;\nexport var formatPrefix;\n\ndefaultLocale({\n  decimal: \".\",\n  thousands: \",\",\n  grouping: [3],\n  currency: [\"$\", \"\"],\n  minus: \"-\"\n});\n\nexport default function defaultLocale(definition) {\n  locale = formatLocale(definition);\n  format = locale.format;\n  formatPrefix = locale.formatPrefix;\n  return locale;\n}\n","import formatDecimal from \"./formatDecimal.js\";\n\nexport default function(x, p) {\n  var d = formatDecimal(x, p);\n  if (!d) return x + \"\";\n  var coefficient = d[0],\n      exponent = d[1];\n  return exponent < 0 ? \"0.\" + new Array(-exponent).join(\"0\") + coefficient\n      : coefficient.length > exponent + 1 ? coefficient.slice(0, exponent + 1) + \".\" + coefficient.slice(exponent + 1)\n      : coefficient + new Array(exponent - coefficient.length + 2).join(\"0\");\n}\n","import formatPrefixAuto from \"./formatPrefixAuto.js\";\nimport formatRounded from \"./formatRounded.js\";\n\nexport default {\n  \"%\": function(x, p) { return (x * 100).toFixed(p); },\n  \"b\": function(x) { return Math.round(x).toString(2); },\n  \"c\": function(x) { return x + \"\"; },\n  \"d\": function(x) { return Math.round(x).toString(10); },\n  \"e\": function(x, p) { return x.toExponential(p); },\n  \"f\": function(x, p) { return x.toFixed(p); },\n  \"g\": function(x, p) { return x.toPrecision(p); },\n  \"o\": function(x) { return Math.round(x).toString(8); },\n  \"p\": function(x, p) { return formatRounded(x * 100, p); },\n  \"r\": formatRounded,\n  \"s\": formatPrefixAuto,\n  \"X\": function(x) { return Math.round(x).toString(16).toUpperCase(); },\n  \"x\": function(x) { return Math.round(x).toString(16); }\n};\n","export default function(x) {\n  return x;\n}\n","import exponent from \"./exponent.js\";\nimport formatGroup from \"./formatGroup.js\";\nimport formatNumerals from \"./formatNumerals.js\";\nimport formatSpecifier from \"./formatSpecifier.js\";\nimport formatTrim from \"./formatTrim.js\";\nimport formatTypes from \"./formatTypes.js\";\nimport {prefixExponent} from \"./formatPrefixAuto.js\";\nimport identity from \"./identity.js\";\n\nvar map = Array.prototype.map,\n    prefixes = [\"y\",\"z\",\"a\",\"f\",\"p\",\"n\",\"µ\",\"m\",\"\",\"k\",\"M\",\"G\",\"T\",\"P\",\"E\",\"Z\",\"Y\"];\n\nexport default function(locale) {\n  var group = locale.grouping === undefined || locale.thousands === undefined ? identity : formatGroup(map.call(locale.grouping, Number), locale.thousands + \"\"),\n      currencyPrefix = locale.currency === undefined ? \"\" : locale.currency[0] + \"\",\n      currencySuffix = locale.currency === undefined ? \"\" : locale.currency[1] + \"\",\n      decimal = locale.decimal === undefined ? \".\" : locale.decimal + \"\",\n      numerals = locale.numerals === undefined ? identity : formatNumerals(map.call(locale.numerals, String)),\n      percent = locale.percent === undefined ? \"%\" : locale.percent + \"\",\n      minus = locale.minus === undefined ? \"-\" : locale.minus + \"\",\n      nan = locale.nan === undefined ? \"NaN\" : locale.nan + \"\";\n\n  function newFormat(specifier) {\n    specifier = formatSpecifier(specifier);\n\n    var fill = specifier.fill,\n        align = specifier.align,\n        sign = specifier.sign,\n        symbol = specifier.symbol,\n        zero = specifier.zero,\n        width = specifier.width,\n        comma = specifier.comma,\n        precision = specifier.precision,\n        trim = specifier.trim,\n        type = specifier.type;\n\n    // The \"n\" type is an alias for \",g\".\n    if (type === \"n\") comma = true, type = \"g\";\n\n    // The \"\" type, and any invalid type, is an alias for \".12~g\".\n    else if (!formatTypes[type]) precision === undefined && (precision = 12), trim = true, type = \"g\";\n\n    // If zero fill is specified, padding goes after sign and before digits.\n    if (zero || (fill === \"0\" && align === \"=\")) zero = true, fill = \"0\", align = \"=\";\n\n    // Compute the prefix and suffix.\n    // For SI-prefix, the suffix is lazily computed.\n    var prefix = symbol === \"$\" ? currencyPrefix : symbol === \"#\" && /[boxX]/.test(type) ? \"0\" + type.toLowerCase() : \"\",\n        suffix = symbol === \"$\" ? currencySuffix : /[%p]/.test(type) ? percent : \"\";\n\n    // What format function should we use?\n    // Is this an integer type?\n    // Can this type generate exponential notation?\n    var formatType = formatTypes[type],\n        maybeSuffix = /[defgprs%]/.test(type);\n\n    // Set the default precision if not specified,\n    // or clamp the specified precision to the supported range.\n    // For significant precision, it must be in [1, 21].\n    // For fixed precision, it must be in [0, 20].\n    precision = precision === undefined ? 6\n        : /[gprs]/.test(type) ? Math.max(1, Math.min(21, precision))\n        : Math.max(0, Math.min(20, precision));\n\n    function format(value) {\n      var valuePrefix = prefix,\n          valueSuffix = suffix,\n          i, n, c;\n\n      if (type === \"c\") {\n        valueSuffix = formatType(value) + valueSuffix;\n        value = \"\";\n      } else {\n        value = +value;\n\n        // Determine the sign. -0 is not less than 0, but 1 / -0 is!\n        var valueNegative = value < 0 || 1 / value < 0;\n\n        // Perform the initial formatting.\n        value = isNaN(value) ? nan : formatType(Math.abs(value), precision);\n\n        // Trim insignificant zeros.\n        if (trim) value = formatTrim(value);\n\n        // If a negative value rounds to zero after formatting, and no explicit positive sign is requested, hide the sign.\n        if (valueNegative && +value === 0 && sign !== \"+\") valueNegative = false;\n\n        // Compute the prefix and suffix.\n        valuePrefix = (valueNegative ? (sign === \"(\" ? sign : minus) : sign === \"-\" || sign === \"(\" ? \"\" : sign) + valuePrefix;\n        valueSuffix = (type === \"s\" ? prefixes[8 + prefixExponent / 3] : \"\") + valueSuffix + (valueNegative && sign === \"(\" ? \")\" : \"\");\n\n        // Break the formatted value into the integer “value” part that can be\n        // grouped, and fractional or exponential “suffix” part that is not.\n        if (maybeSuffix) {\n          i = -1, n = value.length;\n          while (++i < n) {\n            if (c = value.charCodeAt(i), 48 > c || c > 57) {\n              valueSuffix = (c === 46 ? decimal + value.slice(i + 1) : value.slice(i)) + valueSuffix;\n              value = value.slice(0, i);\n              break;\n            }\n          }\n        }\n      }\n\n      // If the fill character is not \"0\", grouping is applied before padding.\n      if (comma && !zero) value = group(value, Infinity);\n\n      // Compute the padding.\n      var length = valuePrefix.length + value.length + valueSuffix.length,\n          padding = length < width ? new Array(width - length + 1).join(fill) : \"\";\n\n      // If the fill character is \"0\", grouping is applied after padding.\n      if (comma && zero) value = group(padding + value, padding.length ? width - valueSuffix.length : Infinity), padding = \"\";\n\n      // Reconstruct the final output based on the desired alignment.\n      switch (align) {\n        case \"<\": value = valuePrefix + value + valueSuffix + padding; break;\n        case \"=\": value = valuePrefix + padding + value + valueSuffix; break;\n        case \"^\": value = padding.slice(0, length = padding.length >> 1) + valuePrefix + value + valueSuffix + padding.slice(length); break;\n        default: value = padding + valuePrefix + value + valueSuffix; break;\n      }\n\n      return numerals(value);\n    }\n\n    format.toString = function() {\n      return specifier + \"\";\n    };\n\n    return format;\n  }\n\n  function formatPrefix(specifier, value) {\n    var f = newFormat((specifier = formatSpecifier(specifier), specifier.type = \"f\", specifier)),\n        e = Math.max(-8, Math.min(8, Math.floor(exponent(value) / 3))) * 3,\n        k = Math.pow(10, -e),\n        prefix = prefixes[8 + e / 3];\n    return function(value) {\n      return f(k * value) + prefix;\n    };\n  }\n\n  return {\n    format: newFormat,\n    formatPrefix: formatPrefix\n  };\n}\n","export default function(grouping, thousands) {\n  return function(value, width) {\n    var i = value.length,\n        t = [],\n        j = 0,\n        g = grouping[0],\n        length = 0;\n\n    while (i > 0 && g > 0) {\n      if (length + g + 1 > width) g = Math.max(1, width - length);\n      t.push(value.substring(i -= g, i + g));\n      if ((length += g + 1) > width) break;\n      g = grouping[j = (j + 1) % grouping.length];\n    }\n\n    return t.reverse().join(thousands);\n  };\n}\n","export default function(numerals) {\n  return function(value) {\n    return value.replace(/[0-9]/g, function(i) {\n      return numerals[+i];\n    });\n  };\n}\n","import exponent from \"./exponent.js\";\n\nexport default function(step) {\n  return Math.max(0, -exponent(Math.abs(step)));\n}\n","import exponent from \"./exponent.js\";\n\nexport default function(step, value) {\n  return Math.max(0, Math.max(-8, Math.min(8, Math.floor(exponent(value) / 3))) * 3 - exponent(Math.abs(step)));\n}\n","import exponent from \"./exponent.js\";\n\nexport default function(step, max) {\n  step = Math.abs(step), max = Math.abs(max) - step;\n  return Math.max(0, exponent(max) - exponent(step)) + 1;\n}\n","var e10 = Math.sqrt(50),\n    e5 = Math.sqrt(10),\n    e2 = Math.sqrt(2);\n\nexport default function(start, stop, count) {\n  var reverse,\n      i = -1,\n      n,\n      ticks,\n      step;\n\n  stop = +stop, start = +start, count = +count;\n  if (start === stop && count > 0) return [start];\n  if (reverse = stop < start) n = start, start = stop, stop = n;\n  if ((step = tickIncrement(start, stop, count)) === 0 || !isFinite(step)) return [];\n\n  if (step > 0) {\n    start = Math.ceil(start / step);\n    stop = Math.floor(stop / step);\n    ticks = new Array(n = Math.ceil(stop - start + 1));\n    while (++i < n) ticks[i] = (start + i) * step;\n  } else {\n    start = Math.floor(start * step);\n    stop = Math.ceil(stop * step);\n    ticks = new Array(n = Math.ceil(start - stop + 1));\n    while (++i < n) ticks[i] = (start - i) / step;\n  }\n\n  if (reverse) ticks.reverse();\n\n  return ticks;\n}\n\nexport function tickIncrement(start, stop, count) {\n  var step = (stop - start) / Math.max(0, count),\n      power = Math.floor(Math.log(step) / Math.LN10),\n      error = step / Math.pow(10, power);\n  return power >= 0\n      ? (error >= e10 ? 10 : error >= e5 ? 5 : error >= e2 ? 2 : 1) * Math.pow(10, power)\n      : -Math.pow(10, -power) / (error >= e10 ? 10 : error >= e5 ? 5 : error >= e2 ? 2 : 1);\n}\n\nexport function tickStep(start, stop, count) {\n  var step0 = Math.abs(stop - start) / Math.max(0, count),\n      step1 = Math.pow(10, Math.floor(Math.log(step0) / Math.LN10)),\n      error = step0 / step1;\n  if (error >= e10) step1 *= 10;\n  else if (error >= e5) step1 *= 5;\n  else if (error >= e2) step1 *= 2;\n  return stop < start ? -step1 : step1;\n}\n","export default function(a, b) {\n  return a < b ? -1 : a > b ? 1 : a >= b ? 0 : NaN;\n}\n","import ascending from \"./ascending.js\";\nimport bisector from \"./bisector.js\";\n\nvar ascendingBisect = bisector(ascending);\nexport var bisectRight = ascendingBisect.right;\nexport var bisectLeft = ascendingBisect.left;\nexport default bisectRight;\n","import ascending from \"./ascending.js\";\n\nexport default function(compare) {\n  if (compare.length === 1) compare = ascendingComparator(compare);\n  return {\n    left: function(a, x, lo, hi) {\n      if (lo == null) lo = 0;\n      if (hi == null) hi = a.length;\n      while (lo < hi) {\n        var mid = lo + hi >>> 1;\n        if (compare(a[mid], x) < 0) lo = mid + 1;\n        else hi = mid;\n      }\n      return lo;\n    },\n    right: function(a, x, lo, hi) {\n      if (lo == null) lo = 0;\n      if (hi == null) hi = a.length;\n      while (lo < hi) {\n        var mid = lo + hi >>> 1;\n        if (compare(a[mid], x) > 0) hi = mid;\n        else lo = mid + 1;\n      }\n      return lo;\n    }\n  };\n}\n\nfunction ascendingComparator(f) {\n  return function(d, x) {\n    return ascending(f(d), x);\n  };\n}\n","export default function(a, b) {\n  return a = +a, b = +b, function(t) {\n    return Math.round(a * (1 - t) + b * t);\n  };\n}\n","export default function(x) {\n  return +x;\n}\n","import {bisect} from \"d3-array\";\nimport {interpolate as interpolateValue, interpolateNumber, interpolateRound} from \"d3-interpolate\";\nimport constant from \"./constant.js\";\nimport number from \"./number.js\";\n\nvar unit = [0, 1];\n\nexport function identity(x) {\n  return x;\n}\n\nfunction normalize(a, b) {\n  return (b -= (a = +a))\n      ? function(x) { return (x - a) / b; }\n      : constant(isNaN(b) ? NaN : 0.5);\n}\n\nfunction clamper(a, b) {\n  var t;\n  if (a > b) t = a, a = b, b = t;\n  return function(x) { return Math.max(a, Math.min(b, x)); };\n}\n\n// normalize(a, b)(x) takes a domain value x in [a,b] and returns the corresponding parameter t in [0,1].\n// interpolate(a, b)(t) takes a parameter t in [0,1] and returns the corresponding range value x in [a,b].\nfunction bimap(domain, range, interpolate) {\n  var d0 = domain[0], d1 = domain[1], r0 = range[0], r1 = range[1];\n  if (d1 < d0) d0 = normalize(d1, d0), r0 = interpolate(r1, r0);\n  else d0 = normalize(d0, d1), r0 = interpolate(r0, r1);\n  return function(x) { return r0(d0(x)); };\n}\n\nfunction polymap(domain, range, interpolate) {\n  var j = Math.min(domain.length, range.length) - 1,\n      d = new Array(j),\n      r = new Array(j),\n      i = -1;\n\n  // Reverse descending domains.\n  if (domain[j] < domain[0]) {\n    domain = domain.slice().reverse();\n    range = range.slice().reverse();\n  }\n\n  while (++i < j) {\n    d[i] = normalize(domain[i], domain[i + 1]);\n    r[i] = interpolate(range[i], range[i + 1]);\n  }\n\n  return function(x) {\n    var i = bisect(domain, x, 1, j) - 1;\n    return r[i](d[i](x));\n  };\n}\n\nexport function copy(source, target) {\n  return target\n      .domain(source.domain())\n      .range(source.range())\n      .interpolate(source.interpolate())\n      .clamp(source.clamp())\n      .unknown(source.unknown());\n}\n\nexport function transformer() {\n  var domain = unit,\n      range = unit,\n      interpolate = interpolateValue,\n      transform,\n      untransform,\n      unknown,\n      clamp = identity,\n      piecewise,\n      output,\n      input;\n\n  function rescale() {\n    var n = Math.min(domain.length, range.length);\n    if (clamp !== identity) clamp = clamper(domain[0], domain[n - 1]);\n    piecewise = n > 2 ? polymap : bimap;\n    output = input = null;\n    return scale;\n  }\n\n  function scale(x) {\n    return isNaN(x = +x) ? unknown : (output || (output = piecewise(domain.map(transform), range, interpolate)))(transform(clamp(x)));\n  }\n\n  scale.invert = function(y) {\n    return clamp(untransform((input || (input = piecewise(range, domain.map(transform), interpolateNumber)))(y)));\n  };\n\n  scale.domain = function(_) {\n    return arguments.length ? (domain = Array.from(_, number), rescale()) : domain.slice();\n  };\n\n  scale.range = function(_) {\n    return arguments.length ? (range = Array.from(_), rescale()) : range.slice();\n  };\n\n  scale.rangeRound = function(_) {\n    return range = Array.from(_), interpolate = interpolateRound, rescale();\n  };\n\n  scale.clamp = function(_) {\n    return arguments.length ? (clamp = _ ? true : identity, rescale()) : clamp !== identity;\n  };\n\n  scale.interpolate = function(_) {\n    return arguments.length ? (interpolate = _, rescale()) : interpolate;\n  };\n\n  scale.unknown = function(_) {\n    return arguments.length ? (unknown = _, scale) : unknown;\n  };\n\n  return function(t, u) {\n    transform = t, untransform = u;\n    return rescale();\n  };\n}\n\nexport default function continuous() {\n  return transformer()(identity, identity);\n}\n","export default function(x) {\n  return function() {\n    return x;\n  };\n}\n","export function initRange(domain, range) {\n  switch (arguments.length) {\n    case 0: break;\n    case 1: this.range(domain); break;\n    default: this.range(range).domain(domain); break;\n  }\n  return this;\n}\n\nexport function initInterpolator(domain, interpolator) {\n  switch (arguments.length) {\n    case 0: break;\n    case 1: {\n      if (typeof domain === \"function\") this.interpolator(domain);\n      else this.range(domain);\n      break;\n    }\n    default: {\n      this.domain(domain);\n      if (typeof interpolator === \"function\") this.interpolator(interpolator);\n      else this.range(interpolator);\n      break;\n    }\n  }\n  return this;\n}\n","import {tickStep} from \"d3-array\";\nimport {format, formatPrefix, formatSpecifier, precisionFixed, precisionPrefix, precisionRound} from \"d3-format\";\n\nexport default function(start, stop, count, specifier) {\n  var step = tickStep(start, stop, count),\n      precision;\n  specifier = formatSpecifier(specifier == null ? \",f\" : specifier);\n  switch (specifier.type) {\n    case \"s\": {\n      var value = Math.max(Math.abs(start), Math.abs(stop));\n      if (specifier.precision == null && !isNaN(precision = precisionPrefix(step, value))) specifier.precision = precision;\n      return formatPrefix(specifier, value);\n    }\n    case \"\":\n    case \"e\":\n    case \"g\":\n    case \"p\":\n    case \"r\": {\n      if (specifier.precision == null && !isNaN(precision = precisionRound(step, Math.max(Math.abs(start), Math.abs(stop))))) specifier.precision = precision - (specifier.type === \"e\");\n      break;\n    }\n    case \"f\":\n    case \"%\": {\n      if (specifier.precision == null && !isNaN(precision = precisionFixed(step))) specifier.precision = precision - (specifier.type === \"%\") * 2;\n      break;\n    }\n  }\n  return format(specifier);\n}\n","import {ticks, tickIncrement} from \"d3-array\";\nimport continuous, {copy} from \"./continuous.js\";\nimport {initRange} from \"./init.js\";\nimport tickFormat from \"./tickFormat.js\";\n\nexport function linearish(scale) {\n  var domain = scale.domain;\n\n  scale.ticks = function(count) {\n    var d = domain();\n    return ticks(d[0], d[d.length - 1], count == null ? 10 : count);\n  };\n\n  scale.tickFormat = function(count, specifier) {\n    var d = domain();\n    return tickFormat(d[0], d[d.length - 1], count == null ? 10 : count, specifier);\n  };\n\n  scale.nice = function(count) {\n    if (count == null) count = 10;\n\n    var d = domain(),\n        i0 = 0,\n        i1 = d.length - 1,\n        start = d[i0],\n        stop = d[i1],\n        step;\n\n    if (stop < start) {\n      step = start, start = stop, stop = step;\n      step = i0, i0 = i1, i1 = step;\n    }\n\n    step = tickIncrement(start, stop, count);\n\n    if (step > 0) {\n      start = Math.floor(start / step) * step;\n      stop = Math.ceil(stop / step) * step;\n      step = tickIncrement(start, stop, count);\n    } else if (step < 0) {\n      start = Math.ceil(start * step) / step;\n      stop = Math.floor(stop * step) / step;\n      step = tickIncrement(start, stop, count);\n    }\n\n    if (step > 0) {\n      d[i0] = Math.floor(start / step) * step;\n      d[i1] = Math.ceil(stop / step) * step;\n      domain(d);\n    } else if (step < 0) {\n      d[i0] = Math.ceil(start * step) / step;\n      d[i1] = Math.floor(stop * step) / step;\n      domain(d);\n    }\n\n    return scale;\n  };\n\n  return scale;\n}\n\nexport default function linear() {\n  var scale = continuous();\n\n  scale.copy = function() {\n    return copy(scale, linear());\n  };\n\n  initRange.apply(scale, arguments);\n\n  return linearish(scale);\n}\n","/**\n * @fileoverview A collection of Ideogram methods that don't fit elsewhere.\n */\n\nimport {select, selectAll} from 'd3-selection';\nimport * as d3fetch from 'd3-fetch';\nimport * as d3brush from 'd3-brush';\nimport * as d3dispatch from 'd3-dispatch';\nimport * as d3format from 'd3-format';\nimport {scaleLinear} from 'd3-scale';\nimport {max} from 'd3-array';\n\nvar d3 = Object.assign(\n  {}, d3fetch, d3brush, d3dispatch, d3format\n);\n\nd3.select = select;\nd3.selectAll = selectAll;\nd3.scaleLinear = scaleLinear;\nd3.max = max;\n\n/**\n * Is the assembly in this.config an NCBI Assembly accession?\n *\n * @returns {boolean}\n */\nfunction assemblyIsAccession() {\n  return (\n    'assembly' in this.config &&\n    /(GCF_|GCA_)/.test(this.config.assembly)\n  );\n}\n\n/**\n * Is the assembly in this.config not from GenBank?\n *\n * @returns {boolean}\n */\nfunction hasNonGenBankAssembly(ideo) {\n  return (\n    'assembly' in ideo.config &&\n    /(GCA_)/.test(ideo.config.assembly) === false\n  );\n}\n\n/**\n * Is the assembly in this.config from GenBank?\n *\n * @returns {boolean}\n */\nfunction hasGenBankAssembly(ideo) {\n  return (\n    'assembly' in ideo.config &&\n    /(GCA_)/.test(ideo.config.assembly)\n  );\n}\n\n/**\n * Returns directory used to fetch data for bands and annotations\n *\n * This simplifies ideogram configuration.  By default, the dataDir is\n * set to an external CDN unless we're serving from the local host, in\n * which case dataDir is deduced from the \"src\" attribute of the ideogram\n * script loaded in the document.\n *\n * @returns {String}\n */\nfunction getDataDir() {\n  var script, tmp, protocol, dataDir, ideogramInLeaf,\n    scripts = document.scripts,\n    host = location.host.split(':')[0],\n    version = Ideogram.version;\n\n  if (host !== 'localhost' && host !== '127.0.0.1') {\n    return (\n      'https://cdn.jsdelivr.net/npm/ideogram@' + version + '/dist/data/bands/native/'\n    );\n  }\n\n  for (var i = 0; i < scripts.length; i++) {\n    script = scripts[i];\n    ideogramInLeaf = /ideogram/.test(script.src.split('/').slice(-1));\n    if ('src' in script && ideogramInLeaf) {\n      tmp = script.src.split('//');\n      protocol = tmp[0];\n      tmp = '/' + tmp[1].split('/').slice(0, -2).join('/');\n      dataDir = protocol + '//' + tmp + '/data/bands/native/';\n      return dataDir;\n    }\n  }\n  return '../data/bands/native/';\n}\n\n/**\n * Rounds an SVG coordinates to two decimal places\n *\n * @param coord SVG coordinate, e.g. 42.1234567890\n * @returns {number} Rounded value, e.g. 42.12\n */\nfunction round(coord) {\n  // Per http://stackoverflow.com/a/9453447, below method is fastest\n  return Math.round(coord * 100) / 100;\n}\n\nfunction onDidRotate(chrModel) {\n  call(this.onDidRotateCallback, chrModel);\n}\n\n/**\n * Get ideogram SVG container\n */\nfunction getSvg() {\n  return d3.select(this.selector).node();\n}\n\nfunction fetch(url, contentType) {\n  var ideo = this,\n    config = ideo.config,\n    headers = new Headers();\n\n  if (config.accessToken) {\n    headers = new Headers({Authorization: 'Bearer ' + config.accessToken});\n  }\n\n  if (contentType === 'text') {\n    return d3.text(url, {headers: headers});\n  } else {\n    return d3.json(url, {headers: headers});\n  }\n}\n\n/**\n * Get organism's taxid (NCBI Taxonomy ID) given its common or scientific name\n */\nfunction getTaxid(name) {\n  var organism, taxid, commonName, scientificName,\n    ideo = this,\n    organisms = ideo.organisms;\n\n  name = slug(name);\n\n  for (taxid in organisms) {\n    organism = organisms[taxid];\n    commonName = slug(organism.commonName);\n    scientificName = slug(organism.scientificName);\n    if (commonName === name || scientificName === name) {\n      return taxid;\n    }\n  }\n\n  return null;\n}\n\n/**\n * Get organism's common name given its taxid\n */\nfunction getCommonName(taxid) {\n  var ideo = this;\n  if (taxid in ideo.organisms) {\n    return ideo.organisms[taxid].commonName;\n  }\n  return null;\n}\n\n/**\n * Get organism's scientific name given its taxid\n */\nfunction getScientificName(taxid) {\n  var ideo = this;\n  if (taxid in ideo.organisms) {\n    return ideo.organisms[taxid].scientificName;\n  }\n  return null;\n}\n\n/**\n* Examples:\n* \"Homo sapiens\" -> \"homo-sapiens\"\n* \"Canis lupus familiaris\" -> \"canis-lupus-familiaris\"\n*/\nfunction slug(value) {\n  return value.toLowerCase().replace(/ /g, '-');\n}\n\nexport {\n  assemblyIsAccession, hasNonGenBankAssembly, hasGenBankAssembly, getDataDir,\n  round, onDidRotate, getSvg, fetch, d3, getTaxid, getCommonName,\n  getScientificName, slug\n};\n","import {Selection, root} from \"./selection/index\";\n\nexport default function(selector) {\n  return typeof selector === \"string\"\n      ? new Selection([document.querySelectorAll(selector)], [document.documentElement])\n      : new Selection([selector == null ? [] : selector], root);\n}\n","export default function max(values, valueof) {\n  let max;\n  if (valueof === undefined) {\n    for (const value of values) {\n      if (value != null\n          && (max < value || (max === undefined && value >= value))) {\n        max = value;\n      }\n    }\n  } else {\n    let index = -1;\n    for (let value of values) {\n      if ((value = valueof(value, ++index, values)) != null\n          && (max < value || (max === undefined && value >= value))) {\n        max = value;\n      }\n    }\n  }\n  return max;\n}\n","var organismMetadata = {\n  9606: {\n    commonName: 'Human',\n    scientificName: 'Homo sapiens',\n    assemblies: {\n      default: 'GCF_000001405.26', // GRCh38\n      GRCh38: 'GCF_000001405.26',\n      GRCh37: 'GCF_000001405.13',\n      NCBI36: 'GCF_000001405.12'\n    }\n  },\n  10090: {\n    commonName: 'Mouse',\n    scientificName: 'Mus musculus',\n    assemblies: {\n      default: 'GCF_000001635.20', // GRCm38\n      GRCm38: 'GCF_000001635.20',\n      MGSCv37: 'GCF_000001635.18'\n    }\n  },\n  9598: {\n    commonName: 'Chimpanzee',\n    scientificName: 'Pan troglodytes',\n    assemblies: {\n      'default': 'GCF_000001515.7',\n      'Pan_tro 3.0': 'GCF_000001515.7'\n    }\n  },\n  10116: {\n    commonName: 'Rat',\n    scientificName: 'Rattus norvegicus',\n    assemblies: {\n      'default': 'GCF_000001895.5',\n      'Rnor_6.0': 'GCF_000001895.5'\n    }\n  },\n  3702: {\n    commonName: 'Thale cress',\n    scientificName: 'Arabidopsis thaliana',\n    assemblies: {\n      default: 'GCF_000001735.3', // TAIR10\n      TAIR10: 'GCF_000001735.3'\n    }\n  },\n  4530: {\n    commonName: 'Rice',\n    scientificName: 'Oryza sativa',\n    assemblies: {\n      'default': 'GCA_001433935.1',\n      'IRGSP-1.0': 'GCA_001433935.1'\n    }\n  },\n  4577: {\n    commonName: 'Maize',\n    scientificName: 'Zea mays',\n    assemblies: {\n      'default': 'GCA_000005005.5',\n      'IRGSP-1.0': 'GCA_001433935.1'\n    }\n  },\n  4641: {\n    commonName: 'Banana',\n    scientificName: 'Musa acuminata',\n    assemblies: {\n      default: 'mock'\n    }\n  },\n  7227: {\n    commonName: 'Fly',\n    scientificName: 'Drosophila melanogaster',\n    assemblies: {\n      'default': 'GCA_000001215.4',\n      'Release 6 plus ISO1 MT': 'GCA_000001215.4'\n    }\n  },\n  7165: {\n    commonName: 'Mosquito',\n    scientificName: 'Anopheles gambiae',\n    assemblies: {\n      default: ''\n    }\n  },\n  746128: {\n    commonName: 'Aspergillis fumigatus',\n    scientificName: 'Aspergillis fumigatus',\n    assemblies: {\n      default: ''\n    }\n  },\n  227321: {\n    commonName: 'Aspergillus nidulans',\n    scientificName: '',\n    assemblies: {\n      default: ''\n    }\n  },\n  5061: {\n    commonName: 'black mold',\n    scientificName: 'Aspergillus niger',\n    assemblies: {\n      default: ''\n    }\n  },\n  5062: {\n    commonName: 'koji',\n    scientificName: 'Aspergillus oryzae',\n    assemblies: {\n      default: ''\n    }\n  },\n  15368: {\n    commonName: '',\n    scientificName: 'Brachypodium distachyon',\n    assemblies: {\n      default: ''\n    }\n  },\n  60711: {\n    commonName: '',\n    scientificName: 'Chlorocebus sabaeus',\n    assemblies: {\n      default: ''\n    }\n  },\n  7719: {\n    commonName: 'Vase tunicate',\n    scientificName: 'Ciona intestinalis',\n    assemblies: {\n      default: ''\n    }\n  },\n  9685: {\n    commonName: 'Cat',\n    scientificName: 'Felis catus',\n    assemblies: {\n      default: ''\n    }\n  },\n  9031: {\n    commonName: 'Chicken',\n    scientificName: 'Gallus gallus',\n    assemblies: {\n      default: ''\n    }\n  },\n  9593: {\n    commonName: 'Gorilla',\n    scientificName: 'Gorilla gorilla',\n    assemblies: {\n      default: ''\n    }\n  },\n  4513: {\n    commonName: 'Barley',\n    scientificName: 'Hordeum vulgare',\n    assemblies: {\n      default: ''\n    }\n  },\n  9541: {\n    commonName: 'Crab-eating macaque',\n    scientificName: 'Macaca fascicularis',\n    assemblies: {\n      default: ''\n    }\n  },\n  9544: {\n    commonName: 'Rhesus macaque',\n    scientificName: 'Macaca mulatta',\n    assemblies: {\n      default: ''\n    }\n  },\n  9597: {\n    commonName: 'Bonobo',\n    scientificName: 'Pan paniscus',\n    assemblies: {\n      default: ''\n    }\n  },\n  9615: {\n    commonName: 'Dog',\n    scientificName: 'Canis lupus familiaris',\n    assemblies: {\n      default: ''\n    }\n  }\n};\n\nexport {organismMetadata};\n","var staticColors, staticCss, staticGradients;\n\nstaticColors = [\n  ['gneg', '#FFF', '#FFF', '#DDD'],\n  ['gpos25', '#C8C8C8', '#DDD', '#BBB'],\n  ['gpos33', '#BBB', '#BBB', '#AAA'],\n  ['gpos50', '#999', '#AAA', '#888'],\n  ['gpos66', '#888', '#888', '#666'],\n  ['gpos75', '#777', '#777', '#444'],\n  ['gpos100', '#444', '#666', '#000'],\n  ['acen', '#FEE', '#FEE', '#FDD'],\n  ['noBands', '#BBB', '#BBB', '#AAA']\n];\n\nstaticCss =\n  '#_ideogram {padding-left: 5px;} ' +\n  '#_ideogram .labeled {padding-left: 15px;} ' +\n  '#_ideogram.labeledLeft {padding-left: 15px; padding-top: 15px;} ' +\n  // Tahoma has great readability and space utilization at small sizes\n  // More: http://ux.stackexchange.com/a/3334\n  '#_ideogram text {font: 9px Tahoma; fill: #000;} ' +\n  '#_ideogram .italic {font-style: italic;} ' +\n  '#_ideogram .chromosome {cursor: pointer; fill: #AAA;}' +\n  '#_ideogram.no-rotate .chromosome {cursor: default;} ' +\n  '#_ideogram .annot {cursor: pointer;}' +\n  '#_ideogram .chrSetLabel {font-weight: bolder;}' +\n  '#_ideogram .ghost {opacity: 0.2;}' +\n  '#_ideogram .hidden {display: none;}' +\n  '#_ideogram .bandLabelStalk line {stroke: #AAA; stroke-width: 1;}' +\n  '#_ideogram .syntenyBorder {stroke:#AAA;stroke-width:1;}' +\n  '#_ideogram rect.cursor {' +\n  '  fill: #F00;' +\n  '  stroke: #F00;' +\n  '  fill-opacity: .3;' +\n  '  shape-rendering: crispEdges;' +\n  '}' +\n  '#_ideogram .brush .selection {' +\n  '  fill: #F00;' +\n  '  stroke: #F00;' +\n  '  fill-opacity: .3;' +\n  '  shape-rendering: crispEdges;' +\n  '}' +\n  '#_ideogram .noBands {fill: #AAA;}' +\n  // NCBI stain density colors\n  '#_ideogram .gneg {fill: #FFF}' +\n  '#_ideogram .gpos25 {fill: #BBB}' +\n  '#_ideogram .gpos33 {fill: #AAA}' +\n  '#_ideogram .gpos50 {fill: #888}' +\n  '#_ideogram .gpos66 {fill: #666}' +\n  '#_ideogram .gpos75 {fill: #444}' +\n  '#_ideogram .gpos100 {fill: #000}' +\n  '#_ideogram .gpos {fill: #000}' +\n  '#_ideogram .acen {fill: #FDD}' +\n  '#_ideogram .stalk {fill: #CCE;}' +\n  '#_ideogram .gvar {fill: #DDF}' +\n  // Used when overlaid with annotations\n  '#_ideogram.faint .gneg {fill: #FFF}' +\n  '#_ideogram.faint .gpos25 {fill: #EEE}' +\n  '#_ideogram.faint .gpos33 {fill: #EEE}' +\n  '#_ideogram.faint .gpos50 {fill: #EEE}' +\n  '#_ideogram.faint .gpos66 {fill: #EEE}' +\n  '#_ideogram.faint .gpos75 {fill: #EEE}' +\n  '#_ideogram.faint .gpos100 {fill: #DDD}' +\n  '#_ideogram.faint .gpos {fill: #DDD}' +\n  '#_ideogram.faint .acen {fill: #FEE}' +\n  '#_ideogram.faint .stalk {fill: #EEF;}' +\n  '#_ideogram.faint .gvar {fill: #EEF}' +\n  // For sheen, i.e. the soft shine in chromosomes\n  '#_ideogram .gneg {fill: url(\"#gneg\")} ' +\n  '#_ideogram .gpos25 {fill: url(\"#gpos25\")} ' +\n  '#_ideogram .gpos33 {fill: url(\"#gpos33\")} ' +\n  '#_ideogram .gpos50 {fill: url(\"#gpos50\")} ' +\n  '#_ideogram .gpos66 {fill: url(\"#gpos66\")} ' +\n  '#_ideogram .gpos75 {fill: url(\"#gpos75\")} ' +\n  '#_ideogram .gpos100 {fill: url(\"#gpos100\")} ' +\n  '#_ideogram .gpos {fill: url(\"#gpos100\")} ' +\n  '#_ideogram .acen {fill: url(\"#acen\")} ' +\n  '#_ideogram .stalk {fill: url(\"#stalk\")} ' +\n  '#_ideogram .gvar {fill: url(\"#gvar\")} ' +\n  '#_ideogram .noBands {fill: url(\"#noBands\")} ' +\n  '#_ideogram .chromosome {fill: url(\"#noBands\")} ';\n\nstaticGradients =\n  '<pattern id=\"stalk\" width=\"2\" height=\"1\" patternUnits=\"userSpaceOnUse\" ' +\n  'patternTransform=\"rotate(30 0 0)\">' +\n  '<rect x=\"0\" y=\"0\" width=\"10\" height=\"2\" fill=\"#CCE\" /> ' +\n  '<line x1=\"0\" y1=\"0\" x2=\"0\" y2=\"100%\" style=\"stroke:#88B; ' +\n  'stroke-width:0.7;\" />' +\n  '</pattern>' +\n  '<pattern id=\"gvar\" width=\"2\" height=\"1\" patternUnits=\"userSpaceOnUse\" ' +\n  'patternTransform=\"rotate(-30 0 0)\">' +\n  '<rect x=\"0\" y=\"0\" width=\"10\" height=\"2\" fill=\"#DDF\" /> ' +\n  '<line x1=\"0\" y1=\"0\" x2=\"0\" y2=\"100%\" style=\"stroke:#99C; ' +\n  'stroke-width:0.7;\" />' +\n  '</pattern>';\n\nexport {staticColors, staticCss, staticGradients};\n","import {organismMetadata} from './organism-metadata';\nimport {staticCss} from './../bands/styles';\n\nfunction configurePloidy(ideo) {\n  if (!ideo.config.ploidy) ideo.config.ploidy = 1;\n\n  if (ideo.config.ploidy > 1) {\n    ideo.sexChromosomes = {};\n    if (!ideo.config.sex) {\n      // Default to 'male' per human, mouse reference genomes.\n      // TODO: The default sex value should probably be the heterogametic sex,\n      // i.e. whichever sex has allosomes that differ in morphology.\n      // In mammals and most insects that is the male.\n      // However, in birds and reptiles, that is female.\n      ideo.config.sex = 'male';\n    }\n    if (ideo.config.ploidy === 2 && !ideo.config.ancestors) {\n      ideo.config.ancestors = {M: '#ffb6c1', P: '#add8e6'};\n      ideo.config.ploidyDesc = 'MP';\n    }\n  }\n}\n\nfunction configureHeight(ideo) {\n  var container, rect, chrHeight;\n\n  if (!ideo.config.chrHeight) {\n    container = ideo.config.container;\n    rect = document.querySelector(container).getBoundingClientRect();\n\n    if (ideo.config.orientation === 'vertical') {\n      chrHeight = rect.height;\n    } else {\n      chrHeight = rect.width;\n    }\n\n    if (container === 'body' || chrHeight === 0) chrHeight = 400;\n    ideo.config.chrHeight = chrHeight;\n  }\n}\n\nfunction configureWidth(ideo) {\n  var chrWidth, chrHeight;\n\n  if (!ideo.config.chrWidth) {\n    chrWidth = 10;\n    chrHeight = ideo.config.chrHeight;\n\n    if (chrHeight < 900 && chrHeight > 500) {\n      chrWidth = Math.round(chrHeight / 40);\n    } else if (chrHeight >= 900) {\n      chrWidth = Math.round(chrHeight / 45);\n    }\n    ideo.config.chrWidth = chrWidth;\n  }\n}\n\nfunction configureMargin(ideo) {\n  if (ideo.config.geometry && ideo.config.geometry === 'collinear') {\n    if ('chrMargin' in ideo.config === false) {\n      ideo.config.chrMargin = 0;\n    }\n    return;\n  }\n  if (!ideo.config.chrMargin) {\n    if (ideo.config.ploidy === 1) {\n      ideo.config.chrMargin = 10;\n    } else {\n      // Defaults polyploid chromosomes to relatively small interchromatid gap\n      ideo.config.chrMargin = Math.round(ideo.config.chrWidth / 4);\n    }\n  }\n  if (ideo.config.showBandLabels) ideo.config.chrMargin += 20;\n}\n\nfunction configureBump(ideo) {\n  ideo.bump = Math.round(ideo.config.chrHeight / 125);\n  ideo.adjustedBump = false;\n  if (ideo.config.chrHeight < 200) {\n    ideo.adjustedBump = true;\n    ideo.bump = 4;\n  }\n}\n\nfunction configureSingleChromosome(config, ideo) {\n  if (config.chromosome) {\n    ideo.config.chromosomes = [config.chromosome];\n    if ('showBandLabels' in config === false) {\n      ideo.config.showBandLabels = true;\n    }\n    if ('rotatable' in config === false) ideo.config.rotatable = false;\n  }\n}\n\nfunction configureOrganisms(ideo) {\n  ideo.organisms = Object.assign({}, organismMetadata);\n  ideo.organismsWithBands = Object.assign({}, ideo.organisms);\n}\n\nfunction configureCallbacks(config, ideo) {\n  if (config.onLoad) ideo.onLoadCallback = config.onLoad;\n  if (config.onLoadAnnots) ideo.onLoadAnnotsCallback = config.onLoadAnnots;\n  if (config.onDrawAnnots) ideo.onDrawAnnotsCallback = config.onDrawAnnots;\n  if (config.onBrushMove) ideo.onBrushMoveCallback = config.onBrushMove;\n  if (config.onCursorMove) ideo.onCursorMoveCallback = config.onCursorMove;\n  if (config.onDidRotate) ideo.onDidRotateCallback = config.onDidRotate;\n  if (config.onWillShowAnnotTooltip) {\n    ideo.onWillShowAnnotTooltipCallback = config.onWillShowAnnotTooltip;\n  }\n  if (config.onClickAnnot) {\n    ideo.onClickAnnotCallback = config.onClickAnnot;\n  }\n}\n\nfunction configureMiscellaneous(ideo) {\n  ideo.chromosomesArray = [];\n  ideo.coordinateSystem = 'iscn';\n  ideo.maxLength = {bp: 0, iscn: 0};\n  ideo.chromosomes = {};\n  ideo.numChromosomes = 0;\n  if (!ideo.config.debug) ideo.config.debug = false;\n  if (!ideo.config.dataDir) ideo.config.dataDir = ideo.getDataDir();\n  if (!ideo.config.container) ideo.config.container = 'body';\n  ideo.selector = ideo.config.container + ' #_ideogram';\n  if (!ideo.config.resolution) ideo.config.resolution = '';\n  if (!ideo.config.orientation) ideo.config.orientation = 'vertical';\n  if (!ideo.config.brush) ideo.config.brush = null;\n  if (!ideo.config.rows) ideo.config.rows = 1;\n  if ('showChromosomeLabels' in ideo.config === false) {\n    ideo.config.showChromosomeLabels = true;\n  }\n  if (!ideo.config.showNonNuclearChromosomes) {\n    ideo.config.showNonNuclearChromosomes = false;\n  }\n  if (!ideo.config.chromosomeScale) {\n    ideo.config.chromosomeScale = 'absolute';\n  }\n}\n\nfunction configureBands(ideo) {\n  if (!ideo.config.showBandLabels) ideo.config.showBandLabels = false;\n\n  if ('showFullyBanded' in ideo.config === false) {\n    ideo.config.showFullyBanded = true;\n  }\n\n  ideo.bandsToShow = [];\n  ideo.bandData = {};\n}\n\nlet configuredCss = staticCss;\nfunction configureTextStyle(ideo) {\n  if (!ideo.config.chrLabelSize) {\n    ideo.config.chrLabelSize = 9;\n    return;\n  }\n\n  const size = ideo.config.chrLabelSize;\n  configuredCss += `#_ideogram text {font-size: ${size}px}`;\n}\n\n/**\n * High-level helper method for Ideogram constructor.\n *\n * @param config Configuration object.  Enables setting Ideogram properties.\n *\n * Docs: https://github.com/eweitz/ideogram/blob/master/api.md\n */\nfunction configure(config) {\n  // Clone the config object, to allow multiple instantiations\n  // without picking up prior ideogram's settings\n  this.config = JSON.parse(JSON.stringify(config));\n\n  configureMiscellaneous(this);\n  configurePloidy(this);\n  configureBands(this);\n  configureHeight(this);\n  configureWidth(this);\n  configureMargin(this);\n  configureCallbacks(config, this);\n  configureOrganisms(this);\n  configureBump(this);\n  configureSingleChromosome(config, this);\n  configureTextStyle(this);\n  this.initAnnotSettings();\n  if (!this.config.geometry || this.config.geometry === 'parallel') {\n    this.config.chrMargin += this.config.chrWidth;\n    if (this.config.annotationsLayout === 'heatmap') {\n      this.config.chrMargin += this.config.annotTracksHeight;\n    } else {\n      this.config.chrMargin += this.config.annotTracksHeight * 2;\n    }\n  }\n  this.init();\n}\n\nexport {configure, configuredCss};\n","/**\n * @fileoverview Functions for collinear chromosomes.\n * Collinear chromosomes form a line together, unlike the default parallel\n * geometry.\n */\n\nimport {d3} from './lib';\n\nfunction labelGenomes(ideo) {\n\n  ideo.config.taxids.forEach((taxid, i) => {\n    var org = ideo.organisms[taxid];\n    // var commonName = slug(org.commonName);\n    var scientificName = org.scientificName;\n    d3.select(ideo.selector)\n      .append('text')\n      .attr('class', 'genomeLabel italic')\n      .attr('x', 50 + 200 * i)\n      .attr('y', 10)\n      .text(scientificName)\n      .attr('text-anchor', 'middle');\n  });\n}\n\n/**\n* Rearrange chromosomes from parallel vertical to collinear vertical\n*\n* Parallel vertical (as in https://eweitz.github.io/ideogram/human)\n* | | |\n*\n* Collinear vertical (as in https://eweitz.github.io/ideogram/orthologs?loci=2:150000000,5:20000000;3:100000000,10:80000000&org=homo-sapiens&org2=mus-musculus)\n* |\n* |\n* |\n*/\nfunction rearrangeChromosomes(chrSets, yOffsets, x, ideo) {\n  var i, chrSet, y, chrLabelX, adjustedX, chr, taxid, orgIndex,\n    config = ideo.config,\n    chrLabelSize = config.chrLabelSize;\n\n  for (i = 0; i < chrSets.length; i++) {\n    chrSet = chrSets[i];\n    y = yOffsets[i] + 23 - chrLabelSize;\n\n    chr = ideo.chromosomesArray[i];\n    taxid = chr.id.split('-')[1];\n    orgIndex = ideo.config.taxids.indexOf(taxid);\n    adjustedX = x - orgIndex * 200 - 30;\n    if (orgIndex === 0) {\n      chrLabelX = -34;\n      adjustedX += ideo.config.chrWidth * 2 - 16;\n    } else {\n      chrLabelX = ideo.config.chrWidth * 2 - 24;\n    }\n\n    if (config.showChromosomeLabels) {\n      const labelSpan = chrSet.querySelector('.chrLabel > tspan');\n      labelSpan.setAttribute('x', chrLabelX);\n      labelSpan.setAttribute('dy', chrLabelSize - 8);\n      chrSet.querySelector('.chrLabel').setAttribute('text-anchor', 'start');\n    }\n    chrSet.setAttribute(\n      'transform', 'rotate(90) translate(' + y + ',' + adjustedX + ')'\n    );\n    chrSet.querySelector('.chromosome').setAttribute(\n      'transform', 'translate(-13, 10)'\n    );\n  }\n\n  labelGenomes(ideo);\n}\n\n/**\n* Get pixel coordinates to use for rearrangement\n*/\nfunction getyOffsets(chrSets, ideo) {\n  var yOffsets, i, index, chr, prevChr, y, prevWidth, prevY, yBump, taxid,\n    seenTaxids = {};\n\n  yOffsets = [];\n  for (i = 0; i < chrSets.length; i++) {\n    chr = ideo.chromosomesArray[i];\n    taxid = chr.id.split('-')[1];\n    index = (i === 0) ? i : i - 1;\n    prevChr = ideo.chromosomesArray[index];\n    if (i === 0 || taxid in seenTaxids === false) {\n      y = 20;\n      seenTaxids[taxid] = 1;\n    } else {\n      prevWidth = prevChr.width;\n      prevY = yOffsets[index];\n      yBump = (ideo.config.showChromosomeLabels ? 0 : 2);\n      y = prevY + prevWidth + yBump + ideo.config.chrMargin;\n    }\n    yOffsets.push(y);\n  }\n\n  return yOffsets;\n}\n\nfunction collinearizeVerticalChromosomes(ideo) {\n  var chrSets, yOffsets, x, height, width,\n    config = ideo.config;\n\n  ideo.config.annotLabelHeight = 12;\n  // var annotLabelHeight = ideo.config.annotLabelHeight;\n\n  if ('demarcateCollinearChromosomes' in ideo.config === false) {\n    ideo.config.demarcateCollinearChromosomes = true;\n  }\n\n  chrSets = document.querySelectorAll('.chromosome-set');\n\n  x = -40;\n\n  yOffsets = getyOffsets(chrSets, ideo);\n  rearrangeChromosomes(chrSets, yOffsets, x, ideo);\n\n  width = Math.round(yOffsets.slice(-1)[0] + 70);\n\n  if (config.multiorganism) {\n    height *= 8;\n    var maxHeight = 0;\n    yOffsets.forEach(d => {\n      if (d > maxHeight) maxHeight = d;\n    });\n    height = maxHeight + 30;\n  } else {\n    height = xOffsets.slice(-1)[0] + 30;\n  }\n\n  d3.select(ideo.selector)\n    .attr('height', height)\n    .attr('width', width);\n\n  d3.select('#_ideogramTrackLabelContainer').remove();\n  d3.select('#_ideogramInnerWrap')\n    .insert('div', ':first-child')\n    .attr('id', '_ideogramTrackLabelContainer')\n    .style('position', 'absolute');\n}\n\nexport default collinearizeVerticalChromosomes;\n","/**\n * @fileoverview Functions for collinear chromosomes.\n * Collinear chromosomes form a line together, unlike the default parallel\n * geometry.\n */\n\nimport {d3} from './lib';\nimport collinearizeVerticalChromosomes from './collinear-vertical';\n\nfunction labelGenomes(ideo) {\n\n  ideo.config.taxids.forEach((taxid, i) => {\n    var org = ideo.organisms[taxid];\n    var config = ideo.config;\n    // var commonName = slug(org.commonName);\n    var scientificName = org.scientificName;\n    d3.select(ideo.selector)\n      .append('text')\n      .attr('class', 'genomeLabel italic')\n      .attr('x', 5)\n      .attr('y', config.chrLabelSize + (200 + (3 * config.chrWidth)) * i)\n      .text(scientificName);\n  });\n}\n\n/**\n* Rearrange chromosomes from parallel horizontal to collinear horizontal\n*\n* Parallel horizontal (as in https://eweitz.github.io/ideogram/mouse)\n*     ---\n*     ---\n*     ---\n*\n* Collinear horizontal (as in https://eweitz.github.io/ideogram/geometry-collinear):\n*     --- --- ---\n*/\nfunction rearrangeChromosomes(chrSets, xOffsets, y, ideo) {\n  var i, chr, chrSet, taxid, x, adjustedY, orgIndex, chrLabelY,\n    config = ideo.config,\n    chrWidth = config.chrWidth,\n    chrLabelSize = config.chrLabelSize;\n\n  for (i = 0; i < chrSets.length; i++) {\n    chrSet = chrSets[i];\n    x = xOffsets[i];\n\n    chr = ideo.chromosomesArray[i];\n    taxid = chr.id.split('-')[1];\n    orgIndex = config.taxids.indexOf(taxid);\n    adjustedY = y + orgIndex * 200;\n    if (orgIndex === 0 && ideo.config.multiorganism) {\n      chrLabelY = chrLabelSize - 4;\n      adjustedY += chrWidth * 2 + chrLabelSize;\n    } else {\n      chrLabelY = chrWidth * 2 + chrLabelSize + 2;\n    }\n\n    if (ideo.config.showChromosomeLabels) {\n      chrSet.querySelector('.chrLabel').setAttribute('y', chrLabelY);\n      chrSet.querySelector('.chrLabel').setAttribute('text-anchor', 'middle');\n    }\n    chrSet.setAttribute('transform', 'translate(' + x + ',' + adjustedY + ')');\n    chrSet.querySelector('.chromosome').setAttribute(\n      'transform', 'translate(-13, 10)'\n    );\n  }\n\n  if (config.multiorganism) {\n    labelGenomes(ideo);\n  }\n}\n\n/**\n* Get pixel coordinates to use for rearrangement\n*/\nfunction getXOffsets(chrSets, ideo) {\n  var xOffsets, i, index, chr, prevChr, x, prevWidth, prevX, xBump, taxid,\n    seenTaxids = {};\n\n  xOffsets = [];\n  for (i = 0; i < chrSets.length; i++) {\n    chr = ideo.chromosomesArray[i];\n    taxid = chr.id.split('-')[1];\n    index = (i === 0) ? i : i - 1;\n    prevChr = ideo.chromosomesArray[index];\n    if (i === 0 || taxid in seenTaxids === false) {\n      x = 20;\n      seenTaxids[taxid] = 1;\n    } else {\n      prevWidth = prevChr.width;\n      prevX = xOffsets[index];\n      xBump = (ideo.config.showChromosomeLabels ? 0 : 2);\n      x = prevX + prevWidth + xBump + ideo.config.chrMargin;\n    }\n    xOffsets.push(x);\n  }\n\n  return xOffsets;\n}\n\n// /**\n//  * Track number of chromosomes in preceding organisms.\n//  * Adds an instance variable to the ideogram object to offset\n//  * chromosome indices.  Needed for multiorganism collinear ideograms.\n//  */\n// function setTaxidChrOffsets(ideo) {\n//   var taxidChrOffsets, taxidChrOffset;\n\n//   taxidChrOffsets = {};\n\n//   taxidChrOffset = 0;\n//   ideo.config.organism.forEach((org) => {\n//     var taxid, numChrs;\n//     taxid = ideo.getTaxid(org);\n//     taxidChrOffsets[taxid] = taxidChrOffset;\n//     numChrs = Object.keys(ideo.chromosomes[taxid]).length;\n//     taxidChrOffset += numChrs;\n//   });\n\n//   ideo.taxidChrOffsets = taxidChrOffsets;\n// }\n\n// /**\n//  * Change chromosome indices for multiorganism collinear ideograms\n//  * This is needed to account for x-offsets.\n//  */\n// function adjustChrIndex(ideo) {\n//   setTaxidChrOffsets(ideo);\n\n//   ideo.chromosomesArray.map((chr) => {\n//     var taxid = chr.id.split('-')[1];\n//     var taxidChrOffset = ideo.taxidChrOffsets[taxid];\n//     chr.chrIndex -= taxidChrOffset;\n//     ideo.chromosomes[taxid][chr.name].chrIndex = chr.chrIndex;\n//   });\n// }\n\nfunction collinearizeChromosomes(ideo) {\n  var chrSets, xOffsets, y, height, width,\n    config = ideo.config,\n    annotHeight = config.annotationHeight || 0;\n\n  if (config.orientation === 'vertical') {\n    collinearizeVerticalChromosomes(ideo);\n    return;\n  }\n\n  // if (config.multiorganism) adjustChrIndex(ideo);\n\n  ideo.config.annotLabelHeight = 12;\n  var annotLabelHeight = ideo.config.annotLabelHeight;\n\n  if ('demarcateCollinearChromosomes' in ideo.config === false) {\n    ideo.config.demarcateCollinearChromosomes = true;\n  }\n\n  chrSets = document.querySelectorAll('.chromosome-set');\n\n  y = (\n    (config.numAnnotTracks * (annotHeight + annotLabelHeight + 4)) -\n    config.chrWidth + 1\n  );\n\n  xOffsets = getXOffsets(chrSets, ideo);\n  rearrangeChromosomes(chrSets, xOffsets, y, ideo);\n\n  height = y + config.chrWidth * 2 + 20;\n\n  if (config.multiorganism) {\n    height *= 8;\n    var maxWidth = 0;\n    xOffsets.forEach(d => {\n      if (d > maxWidth) maxWidth = d;\n    });\n    width = maxWidth + 20;\n  } else {\n    width = xOffsets.slice(-1)[0] + 20;\n  }\n\n  d3.select(ideo.selector)\n    .attr('width', width)\n    .attr('height', height);\n\n  d3.select('#_ideogramTrackLabelContainer').remove();\n  d3.select('#_ideogramInnerWrap')\n    .insert('div', ':first-child')\n    .attr('id', '_ideogramTrackLabelContainer')\n    .style('position', 'absolute');\n}\n\nexport default collinearizeChromosomes;\n","import {d3} from '../lib';\nimport collinearizeChromosomes from '../collinear';\n\nfunction processLabels(config, ideo) {\n  var i, chrID, t0C, t1C;\n\n  if (config.showBandLabels === true) {\n    t0C = new Date().getTime();\n    ideo.hideUnshownBandLabels();\n    t1C = new Date().getTime();\n    if (config.debug) {\n      console.log('Time in showing bands: ' + (t1C - t0C) + ' ms');\n    }\n\n    if (config.orientation === 'vertical') {\n      for (i = 0; i < ideo.chromosomesArray.length; i++) {\n        chrID = '#' + ideo.chromosomesArray[i].id;\n        ideo.rotateChromosomeLabels(d3.select(chrID), i);\n      }\n    }\n  }\n\n  if (config.showChromosomeLabels === true) {\n    ideo.drawChromosomeLabels(ideo.chromosomes);\n  }\n}\n\nfunction processAnnots(ideo) {\n  if (typeof ideo.timeout !== 'undefined') window.clearTimeout(ideo.timeout);\n\n  ideo.rawAnnots = ideo.setOriginalTrackIndexes(ideo.rawAnnots);\n\n  if (ideo.config.annotationsDisplayedTracks) {\n    ideo.annots =\n      ideo.updateDisplayedTracks(ideo.config.annotationsDisplayedTracks);\n  } else {\n    ideo.annots = ideo.processAnnotData(ideo.rawAnnots);\n    if (ideo.config.filterable) ideo.initCrossFilter();\n    ideo.drawProcessedAnnots(ideo.annots);\n  }\n}\n\n/**\n * Load (potentially large) annotation dataset, then process it.\n */\nfunction waitForAndProcessAnnots(ideo) {\n  if (ideo.rawAnnots) {\n    processAnnots(ideo);\n  } else {\n    (function checkAnnotData() {\n      ideo.timeout = setTimeout(function() {\n        if (\n          !ideo.rawAnnots ||\n          (ideo.rawAnnots && typeof ideo.rawAnnots.then !== 'undefined')\n        ) {\n          // Ensure rawAnnots is defined and not a Promise (not \"then\"-able)\n          checkAnnotData();\n        } else {\n          processAnnots(ideo);\n        }\n      }, 50);\n    })();\n  }\n}\n\nfunction reportDebugTimings(config, t0, t0A) {\n\n  var t1A = new Date().getTime();\n  if (config.debug) {\n    console.log('Time in drawChromosome: ' + (t1A - t0A) + ' ms');\n  }\n\n  var t1 = new Date().getTime();\n  if (config.debug) {\n    console.log('Time constructing ideogram: ' + (t1 - t0) + ' ms');\n  }\n}\n\n/**\n * Completes high-level initialization.\n * Draws chromosomes and band labels, rotating as needed;\n * processes and draws annotations;\n * creates brush, emits notification of load completion, etc.\n */\nfunction finishInit(t0) {\n  var t0A = new Date().getTime(),\n    ideo = this,\n    config = ideo.config,\n    confAnnots = config.annotations;\n\n  ideo.initDrawChromosomes();\n\n  if (config.annotationsPath) waitForAndProcessAnnots(ideo);\n\n  processLabels(config, ideo);\n\n  // Create a brush or a click cursor if specified\n  if (config.brush) ideo.createBrush(config.brush);\n  else if (config.cursorPosition) ideo.createClickCursor(config.cursorPosition);\n\n  if (confAnnots) {\n    if (Array.isArray(confAnnots)) {\n      ideo.drawAnnots(confAnnots);\n    } else {\n      // Enable client-side-defined annotations to be formatted\n      // like the wider variety of server-side-defined annotations.\n      // Supports https://github.com/eweitz/ideogram/issues/137\n      ideo.rawAnnots = confAnnots;\n      processAnnots(ideo);\n    }\n  }\n\n  reportDebugTimings(config, t0, t0A);\n\n  ideo.setOverflowScroll();\n\n  if (config.geometry === 'collinear') collinearizeChromosomes(ideo);\n\n  if (ideo.onLoadCallback) ideo.onLoadCallback();\n}\n\nexport {finishInit};\n","export class Ploidy {\n\n  constructor(config) {\n    this._config = config;\n    this._description = this._normalize(this._config.ploidyDesc);\n  }\n\n  // Get number of chromosomes in a chromosome set\n  getChromosomesNumber(setIndex) {\n    if (this._config.ploidyDesc) {\n      var chrSetCode = this._config.ploidyDesc[setIndex];\n      if (chrSetCode instanceof Object) {\n        return Object.keys(chrSetCode)[0].length;\n      } else {\n        return chrSetCode.length;\n      }\n    } else {\n      return this._config.ploidy || 1;\n    }\n  }\n\n  // Normalize use defined description\n  _normalize(description) {\n    var key, descValue,\n      normalized = [];\n\n    if (!description) return description;\n\n    // Loop through description and normalize\n    for (key in description) {\n      descValue = description[key];\n      if (typeof descValue === 'string') {\n        if (this._config.orientation === 'vertical') {\n          descValue = descValue.split('').reverse();\n        }\n        normalized.push({\n          ancestors: descValue,\n          existence: this._getexistenceArray(descValue.length)\n        });\n      } else {\n        normalized.push({\n          ancestors: Object.keys(descValue)[0],\n          existence: descValue[Object.keys(descValue)[0]]\n        });\n      }\n    }\n\n    return normalized;\n  }\n\n  // Get array filled by '11' elements\n  _getexistenceArray(length) {\n    var array = [];\n\n    for (var i = 0; i < length; i++) {\n      array.push('11');\n    }\n\n    return array;\n  }\n\n  getSetSize(chrSetIndex) {\n    if (this._description) {\n      return this._description[chrSetIndex].ancestors.length;\n    } else {\n      return 1;\n    }\n  }\n\n  // Get ancestor letter\n  getAncestor(chrSetIndex, chrIndex) {\n    if (this._description) {\n      return this._description[chrSetIndex].ancestors[chrIndex];\n    } else {\n      return '';\n    }\n  }\n\n  // Check if chromosome's arm should be rendered.\n  // If no description was provided, method returns true and\n  // something another depending on user provided description.\n  exists(chrSetIndex, chrIndex, armIndex) {\n    if (this._description) {\n      var desc =\n        this._description[chrSetIndex].existence[chrIndex][armIndex];\n      return Number(desc) > 0;\n    } else {\n      return true;\n    }\n  }\n\n}\n","import {d3} from '../lib';\n\n/**\n * Chromosome's view utility class\n */\nexport class ChromosomeUtil {\n\n  constructor(node) {\n    this._node = node;\n  }\n\n  getLabel() {\n    var label =\n      d3\n        .select(this._node.parentNode)\n        .select('text.chrLabel')\n        .text();\n    return label;\n  }\n\n  /**\n   * Get chromosome set label\n   */\n  getSetLabel() {\n    var setLabel =\n      d3\n        .select(this._node.parentNode)\n        .select('text.chrSetLabel')\n        .text();\n    return setLabel;\n  }\n}\n","import {d3} from '../lib';\nimport {ChromosomeUtil} from './../views/chromosome-util';\n\nclass Layout {\n\n  constructor(config, ideo) {\n    this._config = config;\n    this._ideo = ideo;\n    this._ploidy = this._ideo._ploidy;\n    this._translate = undefined;\n\n    if ('chrSetMargin' in config) {\n      this.chrSetMargin = config.chrSetMargin;\n    } else {\n      var chrMargin = this._config.chrMargin;\n      this.chrSetMargin = (this._config.ploidy > 1 ? chrMargin : 0);\n    }\n\n    // Chromosome band's size.\n    this._tickSize = 8;\n\n    // Chromosome rotation state.\n    this._isRotated = false;\n  }\n\n  // Get chart left margin\n  _getLeftMargin() {\n    return this.margin.left;\n  }\n\n  // Get rotated chromosome y scale\n  _getYScale() {\n    // 20 is width of rotated chromosome.\n    return 20 / this._config.chrWidth;\n  }\n\n  // Get chromosome labels\n  getChromosomeLabels(chrElement) {\n    var util = new ChromosomeUtil(chrElement),\n      labels = [];\n\n    if (this._ideo.config.ploidy > 1) {\n      labels.push(util.getSetLabel());\n    }\n    labels.push(util.getLabel());\n\n    return labels.filter(function(d) {\n      return d.length > 0;\n    });\n  }\n\n  getChromosomeBandLabelTranslate(band) {\n    var x, y, translate,\n      ideo = this._ideo,\n      tickSize = this._tickSize,\n      orientation = ideo.config.orientation;\n\n    if (orientation === 'vertical') {\n      x = tickSize;\n      y = ideo.round(2 + band.px.start + band.px.width / 2);\n      translate = 'rotate(-90)translate(' + x + ',' + y + ')';\n    } else if (orientation === 'horizontal') {\n      x = ideo.round(-tickSize + band.px.start + band.px.width / 2);\n      y = -10;\n      translate = 'translate(' + x + ',' + y + ')';\n    }\n\n    return {\n      x: x,\n      y: y,\n      translate: translate\n    };\n  }\n\n  didRotate(chrIndex, chrElement) {\n    var ideo, taxid, chrName, bands, chrModel, oldWidth,\n      chrSetElement, transform, scale, scaleRE;\n\n    ideo = this._ideo;\n    taxid = ideo.config.taxid;\n    chrName = chrElement.id.split('-')[0].replace('chr', '');\n    chrModel = ideo.chromosomes[taxid][chrName];\n    bands = chrModel.bands;\n\n    chrSetElement = d3.select(chrElement.parentNode);\n    transform = chrSetElement.attr('transform');\n    scaleRE = /scale\\(.*\\)/;\n    scale = scaleRE.exec(transform);\n    transform = transform.replace(scale, '');\n    chrSetElement.attr('transform', transform);\n\n    oldWidth = chrModel.width;\n\n    chrModel = ideo.getChromosomeModel(bands, chrName, taxid, chrIndex);\n\n    chrModel.oldWidth = oldWidth;\n\n    ideo.chromosomes[taxid][chrName] = chrModel;\n    ideo.drawChromosome(chrModel);\n\n    ideo.handleRotateOnClick();\n\n    if (ideo.rawAnnots) {\n      if (ideo.displayedTrackIndexes) {\n        ideo.updateDisplayedTracks(ideo.displayedTrackIndexes);\n      } else {\n        ideo.annots = ideo.processAnnotData(ideo.rawAnnots);\n        ideo.drawProcessedAnnots(ideo.annots);\n\n        if (ideo.config.filterable) {\n          ideo.initCrossFilter();\n        }\n      }\n    }\n\n    if (ideo.config.showBandLabels === true) {\n      ideo.drawBandLabels(ideo.chromosomes);\n      ideo.hideUnshownBandLabels();\n    }\n\n    if (ideo.onDidRotateCallback) {\n      ideo.onDidRotateCallback(chrModel);\n    }\n  }\n\n  rotate(chrSetIndex, chrIndex, chrElement) {\n    var ideo, otherChrs, ideoBounds, labelSelectors;\n    ideo = this._ideo;\n\n    labelSelectors = (\n      ideo.selector + ' .chrSetLabel, ' + ideo.selector + ' .chrLabel'\n    );\n\n    ideoBounds = document.querySelector(ideo.selector).getBoundingClientRect();\n\n    // Find chromosomes which should be hidden\n    otherChrs = d3.selectAll(ideo.selector + ' g.chromosome')\n      .filter(function() {return this !== chrElement;});\n\n    if (this._isRotated) {\n\n      this._isRotated = false;\n\n      ideo.config.chrHeight = ideo.config.chrHeightOriginal;\n      ideo.config.chrWidth = ideo.config.chrWidthOriginal;\n      ideo.config.annotationHeight = ideo.config.annotationHeightOriginal;\n\n      // Rotate chromosome back\n      this.rotateBack(chrSetIndex, chrIndex, chrElement, function() {\n        // Show all other chromosomes and chromosome labels\n        otherChrs.style('display', null);\n        d3.selectAll(labelSelectors).style('display', null);\n        ideo._layout.didRotate(chrIndex, chrElement);\n      });\n\n    } else {\n\n      this._isRotated = true;\n\n      // Hide all other chromosomes and chromosome labels\n      otherChrs.style('display', 'none');\n      d3.selectAll(labelSelectors).style('display', 'none');\n\n      // Rotate chromosome\n      this.rotateForward(chrSetIndex, chrIndex, chrElement, function() {\n\n        var chrHeight, elementLength, windowLength;\n\n        ideo.config.chrHeightOriginal = ideo.config.chrHeight;\n        ideo.config.chrWidthOriginal = ideo.config.chrWidth;\n        ideo.config.annotationHeightOriginal = ideo.config.annotationHeight;\n\n        const settingsGearWidth = 20;\n\n        if (ideo._layout._class === 'VerticalLayout') {\n          elementLength = ideoBounds.width - settingsGearWidth;\n          windowLength = window.innerWidth - settingsGearWidth;\n        } else {\n          elementLength = ideoBounds.height - 10;\n          windowLength = window.innerHeight - 10;\n        }\n\n        // Set chromosome height to window length or ideogram element length,\n        // whichever is smaller.  This keeps whole chromosome viewable, while\n        // also ensuring the height doesn't exceed what the user specified.\n        if (windowLength < elementLength) {\n          chrHeight = windowLength;\n        } else {\n          chrHeight = elementLength;\n        }\n        chrHeight -= ideo.config.chrMargin * 2;\n        ideo.config.chrHeight = chrHeight;\n\n        // Account for chromosome label\n        // TODO: Make this dynamic, not hard-coded\n        ideo.config.chrWidth *= 2.3;\n\n        ideo.config.annotationHeight *= 1.7;\n\n        ideo._layout.didRotate(chrIndex, chrElement);\n      });\n    }\n  }\n\n  getChromosomeLabelClass() {\n    if (this._config.ploidy === 1) {\n      return 'chrLabel';\n    } else {\n      return 'chrSetLabel';\n    }\n  }\n\n  _getAdditionalOffset() {\n    var config = this._config;\n    var numTracks = config.annotationsNumTracks || config.numAnnotTracks || 1;\n    return (config.annotationHeight || 0) * numTracks;\n  }\n\n  _getChromosomeSetSize(chrSetIndex) {\n    // Get last chromosome set size.\n    var setSize = this._ploidy.getSetSize(chrSetIndex);\n\n    // Increase offset by last chromosome set size\n    return (\n      setSize * this._config.chrWidth * 2 + (this.chrSetMargin)\n    );\n  }\n\n  // Get chromosome set label anchor property\n  getChromosomeSetLabelAnchor() {\n    return 'middle';\n  }\n\n  // Get chromosome label y position.\n  getChromosomeLabelYPosition() {\n    return -5.5;\n  }\n\n  getChromosomeSetLabelYPosition(chrIndex) {\n    if (this._config.ploidy === 1) {\n      return this.getChromosomeLabelYPosition(chrIndex);\n    } else {\n      return -2 * this._config.chrWidth;\n    }\n  }\n\n}\n\nexport default Layout;\n","/**\n* @fileoverview Vertical layout class\n* Ideogram instances with vertical layout are oriented with each chromosome\n* starting at top and ending at bottom, and aligned as columns.\n*/\n\nimport {d3} from '../lib';\nimport Layout from './layout';\n\nclass VerticalLayout extends Layout {\n\n  constructor(config, ideo) {\n    super(config, ideo);\n    this._class = 'VerticalLayout';\n    // Layout margins\n    this.margin = {\n      top: 30,\n      left: 15\n    };\n  }\n\n  rotateForward(chrSetIndex, chrIndex, chrElement, callback) {\n    // TODO: Integrate chrSetIndex and chrIndex to support polyploid rotation.\n\n    var self = this;\n\n    var xOffset = 20;\n\n    var scale = this.getChromosomeScale(chrElement);\n\n    var transform =\n      'translate(' + xOffset + ', 25) ' + scale;\n\n    d3.select(chrElement.parentNode)\n      .transition()\n      .attr('transform', transform)\n      .on('end', callback);\n\n    // Append new chromosome labels\n    var labels = this.getChromosomeLabels(chrElement);\n    var y = (xOffset + self._config.chrWidth) * 1.3;\n    d3.select(this._ideo.getSvg())\n      .append('g')\n      .attr('class', 'tmp')\n      .selectAll('text')\n      .data(labels)\n      .enter()\n      .append('text')\n      .attr('class', function(d, i) {\n        return i === 0 && labels.length === 2 ? 'chrSetLabel' : null;\n      })\n      .attr('x', 0)\n      .attr('y', y).style('opacity', 0)\n      .text(String)\n      .transition()\n      .style('opacity', 1);\n\n    this._ideo.config.orientation = 'horizontal';\n  }\n\n  rotateBack(setIndex, chrIndex, chrElement, callback) {\n\n    var scale = this.getChromosomeScaleBack(chrElement);\n    var translate = this.getChromosomeSetTranslate(setIndex);\n\n    d3.select(chrElement.parentNode)\n      .transition()\n      .attr('transform', translate + ' ' + scale)\n      .on('end', callback);\n\n    d3.selectAll(this._ideo.selector + ' g.tmp')\n      .style('opacity', 0)\n      .remove();\n\n    this._ideo.config.orientation = 'vertical';\n  }\n\n  getHeight() {\n    return this._config.chrHeight + this.margin.top * 1.5;\n  }\n\n  getWidth() {\n    return '97%';\n  }\n\n  getChromosomeBandTickY1() {\n    return 2;\n  }\n\n  getChromosomeBandTickY2() {\n    return 10;\n  }\n\n  getChromosomeSetLabelTranslate() {\n    return 'rotate(-90)';\n  }\n\n  getChromosomeBandLabelAnchor() {\n    return null;\n  }\n\n  getChromosomeScale(chrElement) {\n    var ideoBox, chrBox, scaleX, scaleY;\n\n    ideoBox = d3.select(this._ideo.selector).node().getBoundingClientRect();\n    chrBox = chrElement.getBoundingClientRect();\n\n    scaleX = (ideoBox.width / chrBox.height) * 0.97;\n    scaleY = this._getYScale();\n\n    return 'scale(' + scaleX + ', ' + scaleY + ')';\n  }\n\n  getChromosomeScaleBack(chrElement) {\n    var scale, scaleX, scaleY, chrName, chrModel, taxid, ideo, config;\n\n    ideo = this._ideo;\n    config = ideo.config;\n    taxid = config.taxid;\n\n    chrName = chrElement.id.split('-')[0].replace('chr', '');\n    chrModel = this._ideo.chromosomes[taxid][chrName];\n    scaleX = (chrModel.oldWidth / (config.chrHeight * 3)) * 0.97;\n    scaleY = 1 / this._getYScale();\n    scale = 'scale(' + scaleX + ', ' + scaleY + ')';\n    return scale;\n  }\n\n  getChromosomeSetTranslate(setIndex) {\n    var marginTop = this.margin.top;\n    var chromosomeSetYTranslate = this.getChromosomeSetYTranslate(setIndex);\n    return (\n      'rotate(90) ' +\n      'translate(' + marginTop + ', -' + chromosomeSetYTranslate + ')'\n    );\n  }\n\n  getChromosomeSetYTranslate(setIndex) {\n    // Get additional padding caused by annotation/histogram tracks\n    var pad = this._getAdditionalOffset(),\n      margin = this._config.chrMargin,\n      width = this._config.chrWidth,\n      translate;\n\n    // If no detailed description provided just use one formula for all cases\n    if (!this._config.ploidyDesc) {\n      // TODO:\n      // This part of code contains a lot magic numbers and if\n      // statements for exactly corresponing to original ideogram examples.\n      // But all this stuff should be removed. Calculation of translate\n      // should be a simple formula applied for all cases listed below.\n      // Now they are diffirent because of Layout:_getAdditionalOffset do\n      // not meet for cases when no annotation, when annotation exists and\n      // when histogram used\n\n      if (this._config.annotationsLayout === 'histogram') {\n        var barWidth = this._ideo.config.barWidth;\n        return margin + setIndex * (margin + width + 3) + barWidth * 2;\n      } else {\n        translate = width + setIndex * (margin + width) + pad * 2;\n        if (pad > 0) {\n          return translate;\n        } else {\n          return translate + 4 + (2 * setIndex);\n        }\n      }\n    }\n\n    // If detailed description provided start to calculate offsets\n    // for each chromosome set separately. This should be done only once\n    if (!this._translate) {\n      // First offset equals to zero\n      this._translate = [this._ploidy.getSetSize(0) * width * 2];\n      var prevTranslate;\n      // Loop through description set\n      for (var i = 1; i < this._config.ploidyDesc.length; i++) {\n        prevTranslate = this._translate[i - 1];\n        this._translate[i] = prevTranslate + this._getChromosomeSetSize(i - 1);\n      }\n    }\n\n    return this._translate[setIndex];\n  }\n\n  getChromosomeSetLabelXPosition() {\n    return (this._config.chrWidth * this._config.ploidy) / -2;\n  }\n\n  getChromosomeLabelXPosition() {\n    return this._config.chrWidth / -2;\n  }\n}\n\nexport default VerticalLayout;\n","/**\n* @fileoverview Horizontal layout class\n* Ideogram instances with horizontal layout are oriented with each chromosome\n* starting at left and ending at right, and aligned as rows.\n*/\n\nimport {d3} from '../lib';\nimport Layout from './layout';\n\nclass HorizontalLayout extends Layout {\n\n  constructor(config, ideo) {\n    super(config, ideo);\n    this._class = 'HorizontalLayout';\n    this.margin = {\n      left: 20,\n      top: 30\n    };\n  }\n\n  _getLeftMargin() {\n    var margin = Layout.prototype._getLeftMargin.call(this);\n    if (this._config.ploidy > 1) {\n      margin *= 1.8;\n    }\n\n    return margin;\n  }\n\n  rotateForward(setIndex, chrIndex, chrElement, callback) {\n\n    var xOffset, yOffset, transform, labels;\n\n    xOffset = 30;\n\n    yOffset = xOffset + 7.5;\n\n    transform = (\n      'rotate(90) ' +\n      'translate(' + xOffset + ', -' + yOffset + ') '\n    );\n\n    d3.select(chrElement.parentNode)\n      .transition()\n      .attr('transform', transform)\n      .on('end', callback);\n\n    // Append new chromosome labels\n    labels = this.getChromosomeLabels(chrElement);\n    d3.select(this._ideo.getSvg())\n      .append('g')\n      .attr('class', 'tmp')\n      .selectAll('text')\n      .data(labels)\n      .enter()\n      .append('text')\n      .attr('class', function(d, i) {\n        return i === 0 && labels.length === 2 ? 'chrSetLabel' : null;\n      })\n      .attr('x', xOffset - 4)\n      .attr('y', function(d, i) {\n        return (i + 1 + labels.length % 2) * 12;\n      })\n      .style('text-anchor', 'middle')\n      .style('opacity', 0)\n      .text(String)\n      .transition()\n      .style('opacity', 1);\n\n    this._ideo.config.orientation = 'vertical';\n  }\n\n  rotateBack(setIndex, chrIndex, chrElement, callback) {\n    var translate = this.getChromosomeSetTranslate(setIndex);\n\n    d3.select(chrElement.parentNode)\n      .transition()\n      .attr('transform', translate)\n      .on('end', callback);\n\n    d3.selectAll(this._ideo.selector + ' g.tmp')\n      .style('opacity', 0)\n      .remove();\n\n    this._ideo.config.orientation = 'horizontal';\n  }\n\n  getHeight(taxid) {\n    if (typeof taxid === 'undefined') taxid = this._config.taxids[0];\n    // Get last chromosome set offset.\n    var numChromosomes = this._config.chromosomes[taxid].length;\n    var lastSetOffset = this.getChromosomeSetYTranslate(numChromosomes - 1);\n\n    // Get last chromosome set size.\n    var lastSetSize = this._getChromosomeSetSize(numChromosomes - 1);\n\n    // Increase offset by last chromosome set size\n    lastSetOffset += lastSetSize;\n\n    return lastSetOffset + this._getAdditionalOffset() * 2;\n  }\n\n  getWidth() {\n    return this._config.chrHeight + this.margin.top * 1.5;\n  }\n\n  getChromosomeSetLabelAnchor() {\n    return 'end';\n  }\n\n  getChromosomeBandLabelAnchor() {\n    return null;\n  }\n\n  getChromosomeBandTickY1() {\n    return 2;\n  }\n\n  getChromosomeBandTickY2() {\n    return 10;\n  }\n\n  getChromosomeSetLabelTranslate() {\n    return null;\n  }\n\n  getChromosomeSetTranslate(setIndex) {\n    var leftMargin = this._getLeftMargin();\n    var yTranslate = this.getChromosomeSetYTranslate(setIndex);\n    return 'translate(' + leftMargin + ', ' + yTranslate + ')';\n  }\n\n  getChromosomeSetYTranslate(setIndex) {\n    // If no detailed description provided just use one formula for all cases.\n    if (!this._config.ploidyDesc) {\n      return this._config.chrMargin * (setIndex + 1);\n    }\n\n    // Id detailed description provided start to calculate offsets\n    //  for each chromosome set separately. This should be done only once.\n    if (!this._translate) {\n      // First offset equals to zero.\n      this._translate = [1];\n\n      // Loop through description set\n      for (var i = 1; i < this._config.ploidyDesc.length; i++) {\n        this._translate[i] =\n          this._translate[i - 1] + this._getChromosomeSetSize(i - 1);\n      }\n    }\n\n    return this._translate[setIndex];\n  }\n\n  getChromosomeSetLabelXPosition(i) {\n    if (this._config.ploidy === 1) {\n      return this.getChromosomeLabelXPosition(i);\n    } else {\n      return -20;\n    }\n  }\n\n  getChromosomeSetLabelYPosition(i) {\n    var setSize = this._ploidy.getSetSize(i),\n      config = this._config,\n      chrMargin = config.chrMargin,\n      chrWidth = config.chrWidth,\n      y;\n\n    if (config.ploidy === 1) {\n      y = chrWidth / 2 + 3;\n    } else {\n      y = (setSize * chrMargin) / 2;\n    }\n\n    return y;\n  }\n\n  getChromosomeLabelXPosition() {\n    return -8;\n  }\n\n  getChromosomeLabelYPosition() {\n    return this._config.chrWidth;\n  }\n\n}\n\nexport default HorizontalLayout;\n","/**\n* @fileoverview Paired layout class\n* Ideograms with paired layout group each chromosome in a chromosome set.\n* This enables ploidy support beyond the default haploid; e.g. diploid genomes.\n*/\n\nimport Layout from './layout';\n\nclass PairedLayout extends Layout {\n\n  constructor(config, ideo) {\n    super(config, ideo);\n\n    this._class = 'PairedLayout';\n\n    this.margin = {\n      left: 30\n    };\n  }\n\n  getHeight() {\n    return this._config.chrHeight + this.margin.left * 1.5;\n  }\n\n  getWidth() {\n    return '97%';\n  }\n\n  getChromosomeBandTickY1(chrIndex) {\n    return chrIndex % 2 ? this._config.chrWidth : this._config.chrWidth * 2;\n  }\n\n  getChromosomeBandTickY2(chrIndex) {\n    var width = this._config.chrWidth;\n    return chrIndex % 2 ? width - this._tickSize : width * 2 + this._tickSize;\n  }\n\n  getChromosomeBandLabelAnchor(chrIndex) {\n    return chrIndex % 2 ? null : 'end';\n  }\n\n  getChromosomeBandLabelTranslate(band, chrIndex) {\n    var x = chrIndex % 2 ? 10 : -this._config.chrWidth - 10;\n    var y = this._ideo.round(band.px.start + band.px.width / 2) + 3;\n\n    return {\n      x: y,\n      y: y,\n      translate: 'rotate(-90) translate(' + x + ', ' + y + ')'\n    };\n  }\n\n  getChromosomeLabelXPosition() {\n    return -this._tickSize;\n  }\n\n  getChromosomeSetLabelXPosition() {\n    return this._config.chrWidth / -2;\n  }\n\n  getChromosomeSetLabelTranslate() {\n    return 'rotate(-90)';\n  }\n\n  getChromosomeSetTranslate(setIndex) {\n    var chromosomeSetYTranslate = this.getChromosomeSetYTranslate(setIndex);\n    return (\n      'rotate(90) ' +\n      'translate(' + this.margin.left + ', -' + chromosomeSetYTranslate + ')'\n    );\n  }\n\n  getChromosomeSetYTranslate(setIndex) {\n    return 200 * (setIndex + 1);\n  }\n\n}\n\nexport default PairedLayout;\n","import Layout from './layout';\n\nclass SmallLayout extends Layout {\n\n  constructor(config, ideo) {\n    super(config, ideo);\n\n    this._class = 'SmallLayout';\n\n    this.margin = {\n      left: 36.5,\n      top: 10\n    };\n\n    var taxid = this._ideo.getTaxid(this._ideo.config.organism);\n\n    this.chrs = config.chromosomes[taxid];\n    var numChrs = this.chrs.length;\n\n    // Number of chromosomes per row\n    this.chrsPerRow = Math.ceil(numChrs / config.rows);\n  }\n\n  // rotateForward(setIndex, chrIndex, chrElement, callback) {\n  //   var ideoBox =\n  //      d3.select(this._ideo.selector).node().getBoundingClientRect();\n  //   var chrBox = chrElement.getBoundingClientRect();\n  //\n  //   var scaleX = (ideoBox.width / chrBox.height) * 0.97;\n  //   var scaleY = this._getYScale();\n  //\n  //   transform = 'translate(5, 25) scale(' + scaleX + ', ' + scaleY + ')';\n  //\n  //   d3.select(chrElement.parentNode)\n  //     .transition()\n  //     .attr('transform', transform)\n  //     .on('end', callback);\n  // }\n  //\n  // rotateBack(setIndex, chrIndex, chrElement, callback) {\n  //   var translate = this.getChromosomeSetTranslate(setIndex);\n  //\n  //   d3.select(chrElement.parentNode)\n  //     .transition()\n  //     .attr('transform', translate)\n  //     .on('end', callback);\n  // }\n\n  /**\n   * eweitz 2020-04-13:\n   * This height metric is crude because it is calculated before\n   * the height (\"width\") of each chromosome is calculated.\n   *\n   * It calculates height by multiplying the max height of all chromosomes\n   * (specified in the Ideogram configuration object) by the number of rows.\n   * This ensures the ideogram height doesn't truncate in cases like dog\n   * (where chrX on the second row is longer than chr1 on the first), but it\n   * often leaves too much space on the second row, e.g. for human.\n   *\n   * Ideally, ideogram height would be cumulative height per row, plus top\n   * margin.  This would require calling getHeight _after_ all chromosomes\n   * have had their height (technically, chr.width) assigned.  See draft new\n   * getHeight method below this getHeight method.\n  */\n  getHeight() {\n    var config = this._config;\n    var chrHeight = config.chrHeight * 1.25;\n    return this._config.rows * (chrHeight + this.margin.top);\n  }\n\n  /**\n   * eweitz 2020-04-13:\n   * Draft refinement of getHeight.  See note in classic version above.\n   *\n   * Total height is cumulative height per row, plus top margin\n   */\n  // getHeight() {\n  //   let height = 0;\n  //   const rows = this._config.rows;\n  //   const chrEntries = Object.entries(this.chrs);\n\n  //   for (let i = 0; i < rows; i++) {\n  //     let rowHeight = 0;\n  //     // Starting and ending indexes of chromosomes of this row\n  //     const startIndex = this.chrsPerRow * i;\n  //     const endIndex = this.chrsPerRow * (i + 1) - 1;\n\n  //     for (let j = startIndex; j < endIndex; j++) {\n  //       const thisChrHeight = chrEntries[j][1].width;\n  //       if (thisChrHeight > rowHeight) {\n  //         rowHeight = thisChrHeight;\n  //       }\n  //     }\n  //     height += rowHeight + this.margin.top;\n  //   }\n\n  //   return height;\n  // }\n\n  getWidth() {\n    return '97%';\n  }\n\n  getChromosomeBandLabelTranslate() {\n\n  }\n\n  getChromosomeSetLabelTranslate() {\n    return 'rotate(-90)';\n  }\n\n  getChromosomeSetTranslate(setIndex) {\n    var xOffset, yOffset;\n\n    if (setIndex > this.chrsPerRow - 1) {\n      xOffset = this.margin.left + this._config.chrHeight * 1.3;\n      yOffset = this.getChromosomeSetYTranslate(setIndex - this.chrsPerRow);\n    } else {\n      xOffset = this.margin.left;\n      yOffset = this.getChromosomeSetYTranslate(setIndex);\n    }\n\n    return 'rotate(90) translate(' + xOffset + ', -' + yOffset + ')';\n  }\n\n  getChromosomeSetYTranslate(setIndex) {\n    // Get additional padding caused by annotation tracks\n    var additionalPadding = this._getAdditionalOffset() * 0.3;\n    // If no detailed description provided just use one formula for all cases\n    return (\n      this.margin.left * (setIndex) + this._config.chrWidth +\n      additionalPadding * 2 + additionalPadding * setIndex\n    );\n  }\n\n  getChromosomeSetLabelXPosition(setIndex) {\n    return (\n      ((this._ploidy.getSetSize(setIndex) * this._config.chrWidth + 20) / -2) +\n      (this._config.ploidy > 1 ? 0 : this._config.chrWidth)\n    );\n  }\n\n  getChromosomeLabelXPosition() {\n    return this._config.chrWidth / -2;\n  }\n\n}\n\nexport default SmallLayout;\n","import {d3} from '../lib';\nimport {Ploidy} from '../ploidy';\nimport {getLayout} from '../layouts/layout-adapter';\n\n/**\n * If ploidy description is a string, then convert it to the canonical\n * array format.  String ploidyDesc is used when depicting e.g. parental\n * origin each member of chromosome pair in a human genome.\n * See ploidy-basic.html for usage example.\n */\nfunction setPloidy(ideo) {\n  if (\n    'ploidyDesc' in ideo.config &&\n    typeof ideo.config.ploidyDesc === 'string'\n  ) {\n    var tmp = [];\n    for (var i = 0; i < ideo.numChromosomes; i++) {\n      tmp.push(ideo.config.ploidyDesc);\n    }\n    ideo.config.ploidyDesc = tmp;\n  }\n  // Organism ploidy description\n  ideo._ploidy = new Ploidy(ideo.config);\n}\n\nfunction getContainerSvgClass(ideo) {\n  var svgClass = '';\n  if (ideo.config.showChromosomeLabels) {\n    if (ideo.config.orientation === 'horizontal') {\n      svgClass += 'labeledLeft ';\n    } else {\n      svgClass += 'labeled ';\n    }\n  }\n\n  if (ideo.config.rotatable === false) {\n    svgClass += 'no-rotate ';\n  }\n\n  if (\n    ideo.config.annotationsLayout &&\n    ideo.config.annotationsLayout === 'overlay'\n  ) {\n    svgClass += 'faint';\n  }\n\n  return svgClass;\n}\n\n/**\n * Write tooltip div setup with default styling.\n */\nfunction writeTooltipContainer(ideo) {\n  d3.select(ideo.config.container + ' #_ideogramOuterWrap').append('div')\n    .attr('class', '_ideogramTooltip')\n    .attr('id', '_ideogramTooltip')\n    .style('opacity', 0)\n    .style('position', 'fixed')\n    .style('text-align', 'center')\n    .style('padding', '4px')\n    .style('font', '12px sans-serif')\n    .style('background', 'white')\n    .style('border', '1px solid black')\n    .style('border-radius', '5px')\n    .style('z-index', '9000');\n}\n\nfunction writeContainerDom(ideo) {\n\n  // Remove any previous container content\n  d3.selectAll(ideo.config.container + ' #_ideogramOuterWrap').remove();\n\n  d3.select(ideo.config.container)\n    .append('div')\n    .attr('id', '_ideogramOuterWrap')\n    .append('div')\n    .attr('id', '_ideogramTrackLabelContainer')\n    .style('position', 'absolute');\n\n  d3.select(ideo.config.container + ' #_ideogramOuterWrap').append('div')\n    .attr('id', '_ideogramMiddleWrap') // needed for overflow and scrolling\n    .style('position', 'relative')\n    .style('overflow-x', 'auto')\n    .style('transform', 'translateZ(0)') // add compositing layer for ideogram\n    .append('div')\n    .attr('id', '_ideogramInnerWrap') // needed for overflow and scrolling\n    .append('svg')\n    .attr('id', '_ideogram')\n    .attr('class', getContainerSvgClass(ideo))\n    .attr('width', ideo._layout.getWidth())\n    .attr('height', ideo._layout.getHeight())\n    .html(ideo.getBandColorGradients());\n}\n\n/**\n * Writes the HTML elements that contain this ideogram instance.\n */\nfunction writeContainer(t0) {\n  var ideo = this;\n\n  if (ideo.config.annotationsPath) {\n    ideo.fetchAnnots(ideo.config.annotationsPath);\n  }\n\n  setPloidy(ideo);\n\n  ideo._layout = getLayout(ideo);\n\n  writeContainerDom(ideo);\n\n  ideo.isOnlyIdeogram = document.querySelectorAll('#_ideogram').length === 1;\n  writeTooltipContainer(ideo);\n  ideo.finishInit(t0);\n}\n\nexport {writeContainer};\n","import VerticalLayout from './vertical-layout';\nimport HorizontalLayout from './horizontal-layout';\nimport PairedLayout from './paired-layout';\nimport SmallLayout from './small-layout';\n\nfunction getLayout(ideo) {\n  var config = ideo.config;\n\n  if ('perspective' in config && config.perspective === 'comparative') {\n    return new PairedLayout(config, ideo);\n  } else if ('rows' in config && config.rows > 1) {\n    return new SmallLayout(config, ideo);\n  } else if (config.orientation === 'vertical') {\n    return new VerticalLayout(config, ideo);\n  } else if (config.orientation === 'horizontal') {\n    return new HorizontalLayout(config, ideo);\n  } else {\n    return new VerticalLayout(config, ideo);\n  }\n}\n\nexport {getLayout};\n","import {hasNonGenBankAssembly} from '../lib';\n\nvar lastBandDataUrl = '';\n\nfunction getBandUrl(bandDataFileNames, taxid, ideo) {\n  return ideo.config.dataDir + bandDataFileNames[taxid];\n}\n\nfunction shouldFetchBands(bandDataFileNames, taxid, ideo) {\n  var bandDataUrl = getBandUrl(bandDataFileNames, taxid, ideo);\n  return (\n    !(typeof window.chrBands !== 'undefined' && lastBandDataUrl === '') ||\n    lastBandDataUrl !== bandDataUrl\n  ) &&\n  hasNonGenBankAssembly(ideo) &&\n  taxid in bandDataFileNames;\n}\n\nfunction setBandData(url, fileNames, chrBands, ideo) {\n  var taxid, fetchedTaxid, fileName;\n\n  // Ensures correct taxid is processed in response callback;\n  // using simply upstream 'taxid' variable gives the last\n  // *requested* taxid, which fails when dealing with multiple taxa.\n  for (taxid in fileNames) {\n    fileName = fileNames[taxid];\n    if (url.includes(fileName) && fileName !== '') {\n      fetchedTaxid = taxid;\n    }\n  }\n\n  ideo.bandData[fetchedTaxid] = chrBands;\n}\n\nfunction fetchBands(bandDataFileNames, taxid, t0, ideo) {\n  var bandDataUrl = getBandUrl(bandDataFileNames, taxid, ideo);\n\n  if (!ideo.numBandDataResponses) ideo.numBandDataResponses = 0;\n\n  return fetch(bandDataUrl)\n    .then(function(response) {\n      return response.json().then(function(rawBands) {\n        lastBandDataUrl = bandDataUrl;\n\n        delete window.chrBands; // Remove any previous chrBands variable\n        window.chrBands = rawBands.chrBands;\n\n        setBandData(response.url, bandDataFileNames, chrBands, ideo);\n      });\n    });\n}\n\nexport {shouldFetchBands, fetchBands};\n","/**\n * @fileoveriew Methods for initialization\n */\n\nimport {d3, slug} from '../lib';\nimport {configure} from './configure';\nimport {finishInit} from './finish-init';\nimport {writeContainer} from './write-container';\nimport {shouldFetchBands, fetchBands} from '../bands/fetch';\nimport {organismMetadata} from './organism-metadata';\n\nfunction isHeterogameticChromosome(chrModel, chrIndex, ideo) {\n  var ploidy = ideo.config.ploidy;\n  return (\n    'sex' in ideo.config &&\n      (\n        ploidy === 2 && ideo.sexChromosomes.index + 1 === chrIndex ||\n        ideo.config.sex === 'female' && chrModel.name === 'Y'\n      )\n  );\n}\n\nfunction prepareChromosomes(bandsArray, chrs, taxid, ideo) {\n  var j, bands, chromosome, chrModel, chrIndex;\n\n  for (j = 0; j < chrs.length; j++) {\n    chromosome = chrs[j];\n    if (typeof bandsArray !== 'undefined') bands = bandsArray[j];\n\n    chrIndex = j + ideo.config.taxids.indexOf(taxid);\n    chrModel = ideo.getChromosomeModel(bands, chromosome, taxid, chrIndex);\n\n    if (typeof chromosome !== 'string') {\n      chromosome = chromosome.name.split(' ').slice(-1)[0].replace('chr', '');\n    }\n\n    ideo.chromosomes[taxid][chromosome] = chrModel;\n    ideo.chromosomesArray.push(chrModel);\n\n    if (isHeterogameticChromosome(chrModel, j, ideo)) continue;\n\n    ideo.drawChromosome(chrModel);\n  }\n}\n\nfunction setCoordinateSystem(chrs, ideo) {\n  if (\n    typeof chrBands !== 'undefined' &&\n    chrs.length >= chrBands.length / 2\n  ) {\n    ideo.coordinateSystem = 'bp';\n  }\n}\n\n/**\n * Configures chromosome data and calls downstream chromosome drawing functions\n */\nfunction initDrawChromosomes() {\n  var taxid, i, chrs, bandsArray,\n    ideo = this,\n    taxids = ideo.config.taxids;\n\n  for (i = 0; i < taxids.length; i++) {\n    taxid = taxids[i];\n    chrs = ideo.config.chromosomes[taxid];\n\n    bandsArray = ideo.bandsArray[taxid];\n\n    setCoordinateSystem(chrs, ideo);\n\n    ideo.chromosomes[taxid] = {};\n    ideo.setSexChromosomes(chrs);\n\n    prepareChromosomes(bandsArray, chrs, taxid, ideo);\n\n    if (ideo.config.showBandLabels) ideo.drawBandLabels(ideo.chromosomes);\n    ideo.handleRotateOnClick();\n    ideo._gotChrModels = true; // Prevent issue with errant rat centromeres\n  }\n}\n\n/**\n * Attach any click handlers to rotate and toggle chromosomes\n */\nfunction handleRotateOnClick() {\n  var ideo = this;\n\n  if (!('rotatable' in ideo.config && ideo.config.rotatable === false)) {\n    d3.selectAll(ideo.selector + ' .chromosome').on('click', function() {\n      ideo.rotateAndToggleDisplay(this);\n    });\n  } else {\n    d3.selectAll(ideo.selector + ' .chromosome')\n      .style('cursor', 'default');\n  }\n}\n\n/**\n * Called when Ideogram has finished initializing.\n * Accounts for certain ideogram properties not being set until\n * asynchronous requests succeed, etc.\n */\nfunction onLoad() {\n  call(this.onLoadCallback);\n}\n\nfunction getBandFileName(taxid, accession, ideo) {\n  var organism = ideo.organisms[taxid];\n  var bandFileName = [slug(organism.scientificName)];\n  var assemblies = organism.assemblies;\n  var resolution = ideo.config.resolution;\n\n  if (accession !== assemblies.default) {\n    bandFileName.push(accession);\n  }\n  if (\n    taxid === '9606' &&\n    (accession in assemblies === 'false' &&\n      Object.values(assemblies).includes(config.assembly) ||\n      (resolution !== '' && resolution !== 850))\n  ) {\n    bandFileName.push(resolution);\n  }\n\n  bandFileName = bandFileName.join('-');\n\n  var fullyBandedTaxids = ['9606', '10090', '10116'];\n  if (fullyBandedTaxids.includes(taxid) && !ideo.config.showFullyBanded) {\n    bandFileName += '-no-bands';\n  }\n\n  bandFileName += '.json';\n\n  return bandFileName;\n}\n\nfunction getBandFileNames(taxid, bandFileNames, ideo) {\n  var organism, assemblies, accession, bandFileName,\n    config = ideo.config;\n\n  organism = ideo.organisms[taxid];\n\n  if (!config.assembly) ideo.config.assembly = 'default';\n\n  assemblies = organism.assemblies;\n\n  if (ideo.assemblyIsAccession()) {\n    accession = config.assembly;\n  } else {\n    accession = assemblies[config.assembly];\n  }\n\n  bandFileName = getBandFileName(taxid, accession, ideo);\n\n  if (taxid in ideo.organismsWithBands) {\n    bandFileNames[taxid] = bandFileName;\n  }\n  return bandFileNames;\n}\n\nfunction prepareContainer(taxid, bandFileNames, t0, ideo) {\n\n  if (shouldFetchBands(bandFileNames, taxid, ideo)) {\n    return fetchBands(bandFileNames, taxid, t0, ideo).then(function() {\n      return ideo.processBandData(taxid);\n    });\n  } else {\n    return new Promise(function(resolve) {\n      ideo.processBandData(taxid);\n      resolve([taxid, undefined]);\n    });\n  }\n}\n\nfunction initializeTaxids(ideo) {\n  return new Promise(function(resolve) {\n    if (typeof ideo.config.organism === 'number') {\n      // 'organism' is a taxid, e.g. 9606\n      var taxid = ideo.config.organism;\n      ideo.getOrganismFromEutils(taxid, function() {\n        ideo.getTaxids(resolve);\n      });\n    } else {\n      ideo.getTaxids(resolve);\n    }\n\n  });\n}\n\nfunction getBandsAndPrepareContainer(taxids, t0, ideo) {\n  var bandFileNames, i, taxid,\n    promises = [];\n\n  bandFileNames = {};\n  for (taxid in organismMetadata) {\n    bandFileNames[taxid] = '';\n  }\n\n  for (i = 0; i < taxids.length; i++) {\n    taxid = String(taxids[i]);\n    bandFileNames = getBandFileNames(taxid, bandFileNames, ideo);\n    promises.push(prepareContainer(taxid, bandFileNames, t0, ideo));\n  }\n\n  Promise.all(promises).then(function(taxidsAndBandsArrays) {\n    var taxidAndBandsArray, taxid, bandsArray;\n\n    for (i = 0; i < taxidsAndBandsArrays.length; i++) {\n      taxidAndBandsArray = taxidsAndBandsArrays[i];\n      taxid = taxidAndBandsArray[0];\n      bandsArray = taxidAndBandsArray[1];\n\n      if ('bandsArray' in ideo === false) {\n        ideo.bandsArray = {};\n      }\n\n      ideo.bandsArray[taxid] = bandsArray;\n    }\n    ideo.writeContainer(t0);\n  });\n}\n\n/**\n * Initializes an ideogram.\n * Sets some high-level properties based on instance configuration,\n * fetches band and annotation data if needed, and\n * writes an SVG element to the document to contain the ideogram\n */\n// Prevents race condition when init is called multiple times in\n// quick succession.\n// See https://github.com/eweitz/ideogram/pull/154.\nvar ideoNext = {};\nvar ideoQueued = {};\nvar ideoWait = {};\n\nfunction init(ideo) {\n  ideo = ideo || this;\n  var containerId = ideo.config.container;\n\n  if (ideoWait[containerId]) {\n    ideoQueued[containerId] = true;\n    ideoNext[containerId] = ideo;\n  } else {\n    ideoWait[containerId] = true;\n    initializeTaxids(ideo)\n      .then(function(taxids) {\n\n        var taxid = taxids[0];\n        ideo.config.taxid = taxid;\n        ideo.config.taxids = taxids;\n\n        var t0 = new Date().getTime();\n        getBandsAndPrepareContainer(taxids, t0, ideo);\n\n        ideoWait[containerId] = false;\n        if (ideoQueued[containerId]) {\n          ideoQueued[containerId] = false;\n          init(ideoNext[containerId]);\n        }\n      });\n  }\n}\n\nexport {\n  configure, initDrawChromosomes, handleRotateOnClick,\n  onLoad, init, finishInit, writeContainer\n};\n","/**\n * @fileoverview Parse raw Ideogram.js annotations from a BED file\n * BED documentation: https://genome.ucsc.edu/FAQ/FAQformat#format1\n */\n\nexport class BedParser {\n\n  constructor(bed, ideo) {\n    this.rawAnnots = this.parseBed(bed, ideo);\n  }\n\n  // http://stackoverflow.com/a/5624139\n  static componentToHex(c) {\n    var hex = parseInt(c, 10).toString(16);\n    return hex.length === 1 ? '0' + hex : hex;\n  }\n\n  static rgbToHex(r, g, b) {\n    return (\n      '#' +\n      BedParser.componentToHex(r) +\n      BedParser.componentToHex(g) +\n      BedParser.componentToHex(b)\n    );\n  }\n\n  parseGenomicCoordinates(columns, ucscStyle) {\n    var chr, start, stop, length;\n\n    // These three columns (i.e. fields) are required\n    chr = columns[0];\n    start = parseInt(columns[1], 10);\n    stop = parseInt(columns[2], 10);\n\n    length = stop - start;\n\n    if (ucscStyle) {\n      chr = chr.slice(3);\n    }\n\n    return [chr, start, stop, length];\n  }\n\n  /**\n   * Parses an annotation from a tab-separated line of a BED file\n   */\n  parseAnnotFromTsvLine(tsvLine, chrs, ucscStyle) {\n    var annot, chrIndex, chr, start, rgb, color, label,\n      columns = tsvLine.split(/\\s/g);\n\n    [chr, start, stop, length] =\n      this.parseGenomicCoordinates(columns, ucscStyle);\n\n    chrIndex = chrs.indexOf(chr);\n    if (chrIndex === -1) return [null, null];\n\n    annot = ['', start, length, 0];\n\n    if (columns.length >= 4) {\n      label = columns[3];\n      annot[0] = label;\n    }\n\n    if (columns.length >= 8) {\n      rgb = columns[8].split(',');\n      color = BedParser.rgbToHex(rgb[0], rgb[1], rgb[2]);\n      annot.push(color);\n    }\n\n    return [chrIndex, annot];\n  }\n\n  parseRawAnnots(annots, bedStartIndex, tsvLines, chrs) {\n    var i, line, chrIndex, annot, keys, rawAnnots, ucscStyle;\n\n    ucscStyle = true;\n    if (isNaN(parseInt(tsvLines[bedStartIndex], 10)) === false) {\n      ucscStyle = false;\n    }\n\n    for (i = bedStartIndex; i < tsvLines.length; i++) {\n      line = tsvLines[i];\n      [chrIndex, annot] = this.parseAnnotFromTsvLine(line, chrs, ucscStyle);\n      if (chrIndex !== null) annots[chrIndex].annots.push(annot);\n    }\n\n    keys = ['name', 'start', 'length', 'trackIndex'];\n    if (tsvLines[bedStartIndex].length >= 8) keys.push('color');\n\n    rawAnnots = {keys: keys, annots: annots};\n\n    return rawAnnots;\n  }\n\n  /**\n  * Parses a BED file, returns raw annotations\n  */\n  parseBed(bed, ideo) {\n    var i, chrs, chr, bedStartIndex, rawAnnots,\n      annots = [],\n      tsvLines = bed.split(/\\r\\n|\\n/);\n\n    chrs = Object.keys(ideo.chromosomes[ideo.config.taxid]);\n\n    for (i = 0; i < chrs.length; i++) {\n      chr = chrs[i];\n      annots.push({chr: chr, annots: []});\n    }\n\n    bedStartIndex = 0; // 1 if BED has header (i.e. track line), 0 otherwise\n    if (tsvLines[0].slice(0, 3) === 'chr' || isNaN(parseInt(tsvLines[0], 10))) {\n      bedStartIndex = 1;\n    }\n\n    rawAnnots = this.parseRawAnnots(annots, bedStartIndex, tsvLines, chrs);\n    return rawAnnots;\n  }\n\n}\n","/**\n * @fileoverview Functions used by parallel and collinear heatmaps.\n */\n\nvar reservedTrackKeys = [\n  'name', 'start', 'length', 'trackIndex', 'trackIndexOriginal', 'color'\n];\n\nvar defaultHeatmapColors = {\n  3: ['00B', 'DDD', 'F00'],\n  5: ['00D', '66D', 'DDD', 'F88', 'F00'],\n  17: [\n    '00D', '00D', '00D', '00D', '00D', '44D', '44D', 'DDD', 'DDD',\n    'DDD', 'DDD', 'F88', 'F66', 'F22', 'F22', 'F00', 'F00', 'F00'\n  ]\n};\n\n/**\n * Get label text for displayed tracks from annotation container metadata,\n * heatmap keys, or annotation container keys\n */\nfunction getLabels(ideo) {\n  var annotKeys, labels, heatmaps, i;\n\n  if (ideo.rawAnnots.metadata && ideo.rawAnnots.metadata.trackLabels) {\n    labels = ideo.rawAnnots.metadata.trackLabels;\n  } else if (ideo.config.heatmaps) {\n    labels = [];\n    heatmaps = ideo.config.heatmaps;\n    for (i = 0; i < heatmaps.length; i++) {\n      labels.push(heatmaps[i].key);\n    }\n  } else {\n    annotKeys = ideo.rawAnnots.keys.slice(0);\n    labels = annotKeys.filter(d => !reservedTrackKeys.includes(d));\n  }\n\n  if (ideo.displayedTrackIndexes) {\n    labels = labels.filter(function(d, i) {\n      return ideo.displayedTrackIndexes.includes(i + 1);\n    });\n  }\n\n  return labels;\n}\n\n/**\n * Apply heatmap thresholds that are passed in as annotation metadata\n */\nfunction inflateThresholds(ideo) {\n  var thresholds, colors,\n    rawAnnots = ideo.rawAnnots;\n\n  if (\n    rawAnnots.metadata && !rawAnnots.metadata.heatmapThresholds &&\n    !ideo.config.heatmapThresholds\n  ) {\n    return;\n  }\n\n  if (ideo.config.heatmapThresholds) {\n    thresholds = ideo.config.heatmapThresholds;\n  } else {\n    thresholds = ideo.rawAnnots.metadata.heatmapThresholds;\n  }\n\n  colors = defaultHeatmapColors[thresholds.length + 1];\n  thresholds = thresholds.map((d, i) => {\n    return [d, '#' + colors[i]];\n  });\n\n  thresholds.push(['+', '#' + colors.slice(-1)[0]]);\n\n  return thresholds;\n}\n\n/**\n * Set needed configuration options from raw annotation data.\n * Simplifies heatmap API by inferring reasonable defaults.\n */\nfunction inflateHeatmaps(ideo) {\n  var i, labels, heatmaps, annotationTracks, rawAnnots, displayedTracks,\n    thresholds = ideo.config.heatmapThresholds;\n\n  heatmaps = [];\n  rawAnnots = ideo.rawAnnots;\n  labels = rawAnnots.keys.slice(3);\n\n  annotationTracks = [];\n  displayedTracks = [];\n  if (rawAnnots.metadata || !isNaN(thresholds[0])) {\n    thresholds = inflateThresholds(ideo);\n  }\n\n  for (i = 0; i < labels.length; i++) {\n    heatmaps.push({key: labels[i], thresholds: thresholds});\n    annotationTracks.push({id: labels[i]});\n    displayedTracks.push(i + 1);\n  }\n  ideo.config.annotationsNumTracks = labels.length;\n  ideo.config.annotationsDisplayedTracks = displayedTracks;\n  ideo.config.heatmaps = heatmaps;\n  ideo.config.annotationTracks = annotationTracks;\n}\n\n/**\n * Given annotation value (m), should it use the color in this threshold?\n */\nfunction shouldUseThresholdColor(m, numThresholds, value, prevThreshold,\n  threshold) {\n\n  return (\n    // If this is the last threshold, and\n    // its value is \"+\" and the value is above the previous threshold...\n    m === numThresholds && (\n      threshold === '+' && value > prevThreshold\n    ) ||\n\n    // ... or if the value matches the threshold...\n    value === threshold ||\n\n    // ... or if this isn't the first or last threshold, and\n    // the value is between this threshold and the previous one...\n    m !== 0 && m !== numThresholds && (\n      value <= threshold &&\n      value > prevThreshold\n    ) ||\n\n    // ... or if this is the first threshold and the value is\n    // at or below the threshold\n    m === 0 && value <= threshold\n  );\n}\n\n/**\n * Determine the color of the heatmap annotation.\n */\nfunction getHeatmapAnnotColor(thresholds, value) {\n  var m, numThresholds, thresholdList, threshold, tvNum, thresholdColor,\n    prevThreshold, useThresholdColor, color;\n\n  for (m = 0; m < thresholds.length; m++) {\n    numThresholds = thresholds.length - 1;\n    thresholdList = thresholds[m];\n    threshold = thresholdList[0];\n\n    // The threshold value is usually a number,\n    // but can also be a \"+\" character indicating that\n    // this threshold is anything greater than the previous threshold.\n    tvNum = parseFloat(threshold);\n    if (isNaN(tvNum) === false) threshold = tvNum;\n    if (m !== 0) prevThreshold = parseFloat(thresholds[m - 1][0]);\n    thresholdColor = thresholdList[1];\n\n    useThresholdColor = shouldUseThresholdColor(m, numThresholds, value,\n      prevThreshold, threshold);\n\n    if (useThresholdColor) color = thresholdColor;\n  }\n\n  return color;\n}\n\nexport {\n  getLabels, inflateHeatmaps, inflateThresholds, defaultHeatmapColors,\n  getHeatmapAnnotColor\n};\n","/**\n * @fileoverview Functions for labeling collinear tracks of genome annotations.\n * See track-labels.js for more.\n */\n\nimport {d3} from '../lib';\nimport {getLabels} from './heatmap-lib';\n\nfunction renderTrackLabels(labels, ideo) {\n  var i, x, y, labelContainer, markBump,\n    annotLabelHeight = ideo.config.annotLabelHeight,\n    demarcateChrs = ideo.config.demarcateCollinearChromosomes;\n\n  x = 11; // Close to chrLeft in heatmap-collinear.js.  For tabs.\n  markBump = (demarcateChrs ? 2 : 0); // Make labels flush with demarcations\n\n  labelContainer =\n    d3.select(ideo.config.container + ' #_ideogramTrackLabelContainer');\n  labelContainer.html('');\n\n  y = ideo.config.annotationHeight + annotLabelHeight + 4;\n\n  for (i = 0; i < labels.length; i++) {\n    labelContainer\n      .style('position', 'absolute')\n      .append('div')\n      .attr('class', '_ideogramTrackLabel')\n      .style('opacity', 1)\n      .style('position', 'absolute')\n      .style('text-align', 'center')\n      .style('padding', '1px')\n      .style('font', '11px sans-serif')\n      .style('background', 'white')\n      .style('line-height', '10px')\n      .style('z-index', '5')\n      .style('left', (x + markBump) + 'px')\n      .style('top', (y * i + markBump) + 'px')\n      .style('width', 'max-content')\n      .style('transform-origin', 'bottom left')\n      .style('text-align', 'left')\n      .html(labels[i]);\n  }\n\n}\n\n/**\n * Show the label for this track\n */\nfunction writeTrackLabels(ideo) {\n  var labels = getLabels(ideo);\n  renderTrackLabels(labels, ideo);\n}\n\nexport {writeTrackLabels};\n","/**\n * @fileoverview Functions for collinear heatmaps of genome annotations.\n * See heatmap.js for more.\n */\n\nimport {d3} from '../lib';\nimport {writeTrackLabels} from './track-labels-collinear';\nimport {inflateHeatmaps} from './heatmap-lib';\n\n/**\n * Add canvases that will contain annotations.  One canvas per track.\n */\nfunction writeCanvases(chr, chrLeft, ideo) {\n  var j, trackLeft, trackWidth, canvas, context, id,\n    chrWidth = chr.width,\n    contextArray = [],\n    annotLabelHeight = ideo.config.annotLabelHeight,\n    numAnnotTracks = ideo.config.numAnnotTracks;\n\n  // Create a canvas for each annotation track on this chromosome\n  for (j = 0; j < numAnnotTracks; j++) {\n    trackWidth = ideo.config.annotationHeight + annotLabelHeight + 4;\n    id = chr.id + '-canvas-' + j; // e.g. chr1-9606-canvas-0\n    trackLeft = chrLeft;\n    if (chr.chrIndex > 0) {\n      trackLeft += (ideo.config.chrMargin * chr.chrIndex) - 1;\n    }\n    canvas = d3.select(ideo.config.container + ' #_ideogramInnerWrap')\n      .append('canvas')\n      .attr('id', id)\n      .attr('width', chrWidth + 1)\n      .attr('height', trackWidth)\n      .style('position', 'absolute')\n      .style('left', trackLeft + 'px')\n      .style('top', (trackWidth * j + 1) + 'px');\n    context = canvas.nodes()[0].getContext('2d');\n    contextArray.push([context, chr]);\n  }\n\n  return contextArray;\n}\n\n/**\n * Render annotations on the canvas\n */\nfunction fillCanvasAnnots(annots, contextArray, ideo) {\n  var j, annot, context, chr,\n    annotLabelHeight = ideo.config.annotLabelHeight,\n    annotHeight = ideo.config.annotationHeight,\n    demarcateChrs = ideo.config.demarcateCollinearChromosomes;\n\n  var trackWidth = annotHeight + annotLabelHeight + 4;\n\n  // Fill in the canvas(es) with annotation colors to draw a heatmap\n  for (j = 0; j < annots.length; j++) {\n    annot = annots[j];\n    context = contextArray[annot.trackIndex][0];\n    chr = contextArray[annot.trackIndex][1];\n    context.fillStyle = annot.color;\n    if (demarcateChrs) {\n      if (annot.startPx < 1 || annot.startPx > chr.width - 1) continue;\n      context.fillRect(annot.startPx, 1, 0.5, trackWidth);\n    } else {\n      context.fillRect(annot.startPx, annotLabelHeight + 1, 0.5, annotHeight);\n    }\n  }\n\n  if (demarcateChrs) {\n    for (j = 0; j < contextArray.length; j++) {\n      context = contextArray[j][0];\n      chr = contextArray[j][1];\n      context.fillStyle = '#555';\n      if (chr.chrIndex === 0) context.fillRect(0, 0, 1, trackWidth);\n      context.fillRect(chr.width - 1, 0, 1.1, trackWidth);\n      context.fillRect(0, 0, chr.width + 1, 1);\n      if (ideo.config.chrMargin) context.fillRect(0, 0, 1.1, trackWidth);\n    }\n  }\n}\n\n/**\n * Draw a 1D heatmap of annotations along each chromosome.\n * Ideal for representing very dense annotation sets in a granular manner\n * without subsampling.\n *\n * TODO:\n * - Support in 'vertical' orientation\n * - Support after rotating chromosome on click\n */\nfunction drawHeatmapsCollinear(annotContainers, ideo) {\n  var annots, chrLeft, contextArray, i, chr,\n    prevX = 0,\n    xBump = (ideo.config.showChromosomesLabels) ? 2 : -0.1;\n\n  d3.select(ideo.selector).classed('labeledLeft', false);\n  d3.selectAll(ideo.config.container + ' canvas').remove();\n\n  // Each \"annotationContainer\" represents annotations for a chromosome\n  for (i = 0; i < annotContainers.length; i++) {\n    annots = annotContainers[i].annots;\n    chr = ideo.chromosomesArray[i];\n    if (i === 0) {\n      chrLeft = 12;\n    } else {\n      chrLeft = prevX + ideo.chromosomesArray[i - 1].width + 14;\n      prevX += ideo.chromosomesArray[i - 1].width + xBump;\n    }\n    contextArray = writeCanvases(chr, chrLeft, ideo);\n    fillCanvasAnnots(annots, contextArray, ideo);\n  }\n\n  writeTrackLabels(ideo);\n\n  if (ideo.onDrawAnnotsCallback) ideo.onDrawAnnotsCallback();\n}\n\nexport {drawHeatmapsCollinear, inflateHeatmaps};\n","/**\n * @fileoverview Functions for 2D heatmaps of genome annotations.\n * 2D heatmaps enable showing many (100+) tracks of data in one dimension,\n * for features (e.g. genes) along a dimension of genomic coordinates in\n * chromosome context.\n *\n * TO DO:\n * - Horizontal orientation\n * - Multiple chromosomes\n * - Non-human organisms\n */\n\nimport {d3} from '../lib';\nimport {getHeatmapAnnotColor} from './heatmap-lib';\n\n/**\n * Add one canvas that will contain all annotations.  One canvas per chromosome.\n */\nfunction writeCanvas(chr, ideoHeight, width, ideo) {\n  var left, canvas, context, id;\n\n  id = chr.id + '-canvas'; // e.g. chr1-9606-canvas\n  left = (ideo.config.chrWidth * 2) + ideo.config.annotationHeight - 0.5;\n  canvas = d3.select(ideo.config.container + ' #_ideogramInnerWrap')\n    .append('canvas')\n    .attr('id', id)\n    .attr('width', width)\n    .attr('height', ideoHeight)\n    .style('position', 'absolute')\n    .style('left', left + 'px')\n    .style('top', '0px');\n  context = canvas.nodes()[0].getContext('2d');\n\n  return context;\n}\n\n/**\n * Render annotations on the canvas.\n *\n * These annotations are 2D; each annotation has many values, each on a track.\n */\nfunction fillCanvasAnnotValues(annot, context, ideo) {\n  var i, x, values,\n    annotHeight = ideo.config.annotationHeight,\n    ideoMarginTop = ideo._layout.margin.top;\n\n  values = annot.values;\n\n  // Fill canvas with annotation colors to draw the heatmap\n  for (i = 0; i < values.length; i++) {\n    context.fillStyle = values[i];\n    x = (i - 1) * annotHeight;\n    context.fillRect(x, annot.startPx + ideoMarginTop, annotHeight, 2);\n  }\n}\n\n/**\n * Draw a 2D heatmap of annotations along one chromosome.\n *\n * TODO:\n * - Support in 'horizontal' orientation\n * - Support after rotating chromosome on click\n */\nfunction drawHeatmaps2d(annotContainers, ideo) {\n  var annot, context, i, chr,\n    container = ideo.config.container,\n    ideoMarginTop = ideo._layout.margin.top,\n    ideoHeight = ideo.config.chrHeight + ideoMarginTop,\n    width = ideo.config.annotationHeight * annotContainers[0].values.length;\n\n  d3.selectAll(container + ' canvas').remove();\n\n  d3.select(container + ' #_ideogramInnerWrap')\n    .style('max-width', width + 'px');\n  d3.select(container + ' #_ideogram').attr('width', width);\n\n  chr = ideo.chromosomesArray[0];\n\n  context = writeCanvas(chr, ideoHeight, width, ideo);\n\n  // Each \"annotationContainer\" represents annotations for a chromosome\n  for (i = 0; i < annotContainers.length; i++) {\n    annot = annotContainers[i];\n    fillCanvasAnnotValues(annot, context, ideo);\n  }\n\n  if (ideo.onDrawAnnotsCallback) {\n    ideo.onDrawAnnotsCallback();\n  }\n}\n\nfunction add2dAnnotsForChr(annots, omittedAnnots, annotsByChr, chrModel,\n  m, keys, ideo) {\n  var j, k, annot, ra, stop, stopPx, color,\n    thresholds = ideo.config.heatmapThresholds;\n\n  for (j = 0; j < annotsByChr.annots.length; j++) {\n    ra = annotsByChr.annots[j];\n    annot = {};\n\n    annot.values = []; // one value per track\n\n    for (k = 0; k < 3; k++) {\n      annot[keys[k]] = ra[k];\n    }\n\n    for (k = 3; k < keys.length; k++) {\n      color = getHeatmapAnnotColor(thresholds, ra[k]);\n      annot.values.push(color);\n    }\n\n    stop = annot.start + annot.length;\n\n    annot.chr = annotsByChr.chr;\n    annot.chrIndex = m;\n    annot.startPx = ideo.convertBpToPx(chrModel, annot.start);\n    stopPx = ideo.convertBpToPx(chrModel, stop);\n    annot.px = Math.round((annot.startPx + stopPx) / 2);\n\n    annots.push(annot);\n  }\n\n  annots.shift();\n\n  return [annots, omittedAnnots];\n}\n\nexport {drawHeatmaps2d, add2dAnnotsForChr};\n","/**\n * @fileoverview Functions for labeling tracks of genome annotations.\n * Tracks are columns of annotations that run beside a chromosome.\n * Labeling tracks with descriptive names makes them easier to understand.\n */\n\nimport {d3} from '../lib';\nimport {getLabels} from './heatmap-lib';\n\n/**\n * Start a timer that, upon expiring, hides the track label.\n *\n * To enable users to copy label content to their clipboard, a timer is\n * used to control when the label disappears.  It starts when the user's\n * cursor leaves the track or the label.  If the user moves the cursor\n * back over the annot or label after the timer starts and before it expires,\n * then the timer is cleared.\n */\nfunction startHideTrackLabelTimeout(ideo) {\n  if (ideo.config.showTrackLabel === false) return;\n\n  ideo.hideTrackLabelTimeout = window.setTimeout(function() {\n    d3.select(ideo.config.container + ' #_ideogramTrackLabel').transition()\n      .duration(500)\n      .style('opacity', 0);\n  }, 250);\n}\n\n/**\n * Write label div setup with default styling.\n */\nfunction writeTrackLabelContainer(ideo) {\n  d3.select(ideo.config.container + ' #_ideogramTrackLabelContainer')\n    .append('div')\n    .attr('id', '_ideogramTrackLabel')\n    .style('opacity', 0)\n    .style('position', 'absolute')\n    .style('text-align', 'center')\n    .style('padding', '1px')\n    .style('font', '11px sans-serif')\n    .style('background', 'white')\n    .style('line-height', '10px')\n    .style('z-index', '9000');\n}\n\n/**\n * Display track labels on the page\n */\nfunction renderTrackLabels(top, left, ideo) {\n  d3.select(ideo.config.container + ' #_ideogramTrackLabel')\n    .style('opacity', 1) // Make label visible\n    .style('left', left + 'px')\n    .style('top', top + 'px')\n    .style('width', 'max-content')\n    .style('transform-origin', 'bottom left')\n    .style('text-align', 'left')\n    .on('mouseover', function() {\n      clearTimeout(ideo.hideTrackLabelTimeout);\n    })\n    .on('mouseout', function() {\n      startHideTrackLabelTimeout(ideo);\n    });\n}\n\n/**\n * Get left and top (x and y) offset for track label text\n */\nfunction getTrackLabelOffsets(labels, trackCanvas, ideo) {\n  var firstTrackId, firstTrack, trackBox, labelBox, ideoBox, left, top,\n    marginHack = 7; // TODO: Make this dynamic\n\n  firstTrackId = trackCanvas.id.split('-').slice(0, -1).join('-') + '-0';\n  firstTrack = d3.select(ideo.config.container + ' #' + firstTrackId)\n    .nodes()[0];\n  trackBox = firstTrack.getBoundingClientRect();\n\n  labelBox = d3.select(ideo.config.container + ' #_ideogramTrackLabel')\n    .nodes()[0].getBoundingClientRect();\n  ideoBox = d3.select(ideo.config.container).nodes()[0]\n    .getBoundingClientRect();\n\n  left = Math.round(trackBox.left + labelBox.width) - trackBox.width - 1;\n  left -= ideoBox.left - marginHack;\n  top = -(labels.split('<br>').length - 2) * trackBox.width + 2;\n\n  return [left, top];\n}\n\n/**\n * Show the label for this track\n */\nfunction showTrackLabel(trackCanvas, ideo) {\n  var labels, left, top;\n\n  clearTimeout(ideo.hideTrackLabelTimeout);\n\n  labels = getLabels(ideo);\n  labels = labels.join('<br>');\n\n  // Clear any previous positioning, write track label text to DOM\n  d3.select(ideo.config.container + ' #_ideogramTrackLabel')\n    .interrupt() // Stop any in-progress disapperance\n    .style('top', '')\n    .style('left', '')\n    .style('transform', null)\n    .style('transform', 'rotate(-90deg)')\n    .html(labels);\n\n  [left, top] = getTrackLabelOffsets(labels, trackCanvas, ideo);\n\n  renderTrackLabels(top, left, ideo);\n}\n\nexport {\n  startHideTrackLabelTimeout, writeTrackLabelContainer, showTrackLabel\n};\n","/**\n * @fileoverview Functions for 2D heatmaps of genome annotations.\n * Heatmaps provide an easy way to visualize very dense annotation data.\n * Unlike the rest of Ideogram's graphics, which use SVG, heatmaps are\n * rendered using the Canvas element.\n */\n\nimport {d3} from '../lib';\nimport {drawHeatmapsCollinear} from './heatmap-collinear';\nimport {drawHeatmaps2d} from './heatmap-2d';\nimport {getHeatmapAnnotColor} from './heatmap-lib';\n\nimport {\n  startHideTrackLabelTimeout, writeTrackLabelContainer, showTrackLabel\n} from './track-labels';\n\n/**\n * Add canvases that will contain annotations.  One canvas per track.\n */\nfunction writeCanvases(chr, chrLeft, ideoHeight, ideo) {\n  var j, trackLeft, trackWidth, canvas, context, id,\n    contextArray = [],\n    numAnnotTracks = ideo.config.numAnnotTracks;\n\n  var marginHack = 7; // TODO: Make this dynamic\n\n  // Create a canvas for each annotation track on this chromosome\n  for (j = 0; j < numAnnotTracks; j++) {\n    trackWidth = ideo.config.annotationHeight;\n    id = chr.id + '-canvas-' + j; // e.g. chr1-9606-canvas-0\n    trackLeft = chrLeft - trackWidth * (numAnnotTracks - j) - marginHack;\n    canvas = d3.select(ideo.config.container + ' #_ideogramInnerWrap')\n      .append('canvas')\n      .attr('id', id)\n      .attr('width', trackWidth)\n      .attr('height', ideoHeight)\n      .style('position', 'absolute')\n      .style('left', trackLeft + 'px');\n    context = canvas.nodes()[0].getContext('2d');\n    contextArray.push(context);\n  }\n\n  return contextArray;\n}\n\n/**\n * Render annotations on the canvas\n */\nfunction fillCanvasAnnots(annots, contextArray, chrWidth, ideoMarginTop) {\n  var j, annot, context, x;\n\n  // Fill in the canvas(es) with annotation colors to draw a heatmap\n  for (j = 0; j < annots.length; j++) {\n    annot = annots[j];\n    context = contextArray[annot.trackIndex];\n    context.fillStyle = annot.color;\n    x = annot.trackIndex - 1;\n    context.fillRect(x, annot.startPx + ideoMarginTop, chrWidth, 0.5);\n  }\n}\n\n/**\n * Draw a 1D heatmap of annotations along each chromosome.\n * Ideal for representing very dense annotation sets in a granular manner\n * without subsampling.\n *\n * TODO:\n * - Support in 'horizontal' orientation\n * - Support after rotating chromosome on click\n */\nfunction drawHeatmaps(annotContainers) {\n  var annots, chrLeft, contextArray, chrWidth, i, chr,\n    ideo = this,\n    config = ideo.config,\n    ideoMarginTop = ideo._layout.margin.top,\n    ideoHeight = config.chrHeight + ideoMarginTop;\n\n  if (config.geometry === 'collinear') {\n    return drawHeatmapsCollinear(annotContainers, ideo);\n  } else if (config.annotationsLayout === 'heatmap-2d') {\n    return drawHeatmaps2d(annotContainers, ideo);\n  }\n\n  d3.selectAll(ideo.config.container + ' canvas').remove();\n\n  writeTrackLabelContainer(ideo);\n\n  // Each \"annotationContainer\" represents annotations for a chromosome\n  for (i = 0; i < annotContainers.length; i++) {\n\n    annots = annotContainers[i].annots;\n    chr = ideo.chromosomesArray[i];\n    chrWidth = ideo.config.chrWidth;\n    chrLeft = ideo._layout.getChromosomeSetYTranslate(i);\n\n    contextArray = writeCanvases(chr, chrLeft, ideoHeight, ideo);\n    fillCanvasAnnots(annots, contextArray, chrWidth, ideoMarginTop);\n  }\n\n  d3.selectAll(ideo.config.container + ' canvas')\n    .on('mouseover', function() {showTrackLabel(this, ideo);})\n    .on('mouseout', function() {startHideTrackLabelTimeout(ideo);});\n\n  if (ideo.onDrawAnnotsCallback) {\n    ideo.onDrawAnnotsCallback();\n  }\n}\n\n/**\n * Set color and track index for raw annotation objects.\n */\nfunction getNewRawAnnots(heatmapKeyIndexes, rawAnnots, ideo) {\n  var j, k, ra, newRa, value, thresholds, color, trackIndex,\n    newRas = [];\n\n  for (j = 0; j < rawAnnots.length; j++) {\n    ra = rawAnnots[j];\n    for (k = 0; k < heatmapKeyIndexes.length; k++) {\n      newRa = ra.slice(0, 3); // name, start, length\n\n      value = ra[heatmapKeyIndexes[k]];\n      thresholds = ideo.config.heatmaps[k].thresholds;\n      color = getHeatmapAnnotColor(thresholds, value);\n\n      trackIndex = k;\n      newRa.push(trackIndex, color, value);\n      newRas.push(newRa);\n    }\n  }\n\n  return newRas;\n}\n\nfunction getNewRawAnnotContainers(heatmapKeyIndexes, rawAnnotBoxes, ideo) {\n  var raContainer, chr, rawAnnots, newRas, i,\n    newRaContainers = [];\n\n  for (i = 0; i < rawAnnotBoxes.length; i++) {\n    raContainer = rawAnnotBoxes[i];\n    chr = raContainer.chr;\n\n    rawAnnots = raContainer.annots;\n    newRas = getNewRawAnnots(heatmapKeyIndexes, rawAnnots, ideo);\n\n    newRaContainers.push({chr: chr, annots: newRas});\n  }\n  return newRaContainers;\n}\n\nfunction reportPerformance(t0, ideo) {\n  var t1 = new Date().getTime();\n  if (ideo.config.debug) {\n    console.log('Time in deserializeAnnotsForHeatmap: ' + (t1 - t0) + ' ms');\n  }\n}\n\n/**\n * Deserialize compressed annotation data into a format suited for heatmaps.\n *\n * This enables the annotations to be downloaded from a server without the\n * requested annotations JSON needing to explicitly specify track index or\n * color.  The track index and color are inferred from the \"heatmaps\" Ideogram\n * configuration option defined before ideogram initialization.\n *\n * This saves time for the user.\n *\n * @param rawAnnotsContainer {Object} Raw annotations as passed from server\n */\nfunction deserializeAnnotsForHeatmap(rawAnnotsContainer) {\n  var newRaContainers, heatmapKey, heatmapKeyIndexes, i,\n    t0 = new Date().getTime(),\n    keys = rawAnnotsContainer.keys,\n    rawAnnotBoxes = rawAnnotsContainer.annots,\n    ideo = this;\n\n  heatmapKeyIndexes = [];\n  for (i = 0; i < ideo.config.heatmaps.length; i++) {\n    heatmapKey = ideo.config.heatmaps[i].key;\n    heatmapKeyIndexes.push(keys.indexOf(heatmapKey));\n  }\n\n  newRaContainers =\n    getNewRawAnnotContainers(heatmapKeyIndexes, rawAnnotBoxes, ideo);\n\n  keys.splice(3, 0, 'trackIndex');\n  keys.splice(4, 0, 'color');\n\n  ideo.rawAnnots.keys = keys;\n  ideo.rawAnnots.annots = newRaContainers;\n\n  reportPerformance(t0, ideo);\n}\n\nexport {drawHeatmaps, deserializeAnnotsForHeatmap};\n","import {d3} from '../lib';\n\n/**\n * Optional callback, invoked when annotations are drawn\n */\nfunction onLoadAnnots() {\n  call(this.onLoadAnnotsCallback);\n}\n\n/**\n * Optional callback, invoked when annotations are drawn\n */\nfunction onDrawAnnots() {\n  call(this.onDrawAnnotsCallback);\n}\n\n/**\n * Starts a timer that, upon expiring, hides the annotation tooltip.\n *\n * To enable users to copy tooltip content to their clipboard, a timer is\n * used to control when the tooltip disappears.  It starts when the user's\n * cursor leaves the annotation or the tooltip.  If the user moves the cursor\n * back over the annot or tooltip after the timer starts and before it expires,\n * then the timer is cleared.\n */\nfunction startHideAnnotTooltipTimeout() {\n\n  if (this.config.showAnnotTooltip === false) {\n    return;\n  }\n\n  this.hideAnnotTooltipTimeout = window.setTimeout(function() {\n    d3.select('._ideogramTooltip').transition()\n      .duration(500)\n      .style('opacity', 0)\n      .style('pointer-events', 'none');\n  }, 250);\n}\n\nfunction writeTooltip(tooltip, content, matrix, yOffset, ideo) {\n  tooltip.html(content)\n    .style('opacity', 1) // Make tooltip visible\n    .style('left', matrix.e + 'px')\n    .style('top', (matrix.f - yOffset) + 'px')\n    .style('pointer-events', null) // Prevent bug in clicking chromosome\n    .on('mouseover', function() {\n      clearTimeout(ideo.hideAnnotTooltipTimeout);\n    })\n    .on('mouseout', function() {\n      ideo.startHideAnnotTooltipTimeout();\n    });\n}\n\nfunction getContentAndYOffset(annot) {\n  var content, yOffset, range, displayName;\n\n  range = 'chr' + annot.chr + ':' + annot.start.toLocaleString();\n  if (annot.length > 0) {\n    // Only show range if stop differs from start\n    range += '-' + annot.stop.toLocaleString();\n  }\n  content = range;\n  yOffset = 24;\n\n  if (annot.name) {\n    displayName = annot.displayName ? annot.displayName : annot.name;\n    content = displayName + '<br/>' + content;\n    yOffset += 8;\n  }\n\n  return [content, yOffset];\n}\n\n/**\n * Optional callback, invoked before showing annotation tooltip\n */\nfunction onWillShowAnnotTooltip(annot) {\n  call(this.onWillShowAnnotTooltipCallback, annot);\n}\n\n/**\n * Optional callback, invoked on clicking annotation\n */\nfunction onClickAnnot(annot) {\n  this.onClickAnnotCallback(annot);\n}\n\n/**\n * Shows a tooltip for the given annotation.\n *\n * See notes in startHideAnnotTooltipTimeout about show/hide logic.\n *\n * @param annot {Object} Processed annotation object\n * @param context {Object} \"This\" of the caller -- an SVG path DOM object\n */\nfunction showAnnotTooltip(annot, context) {\n  var matrix, content, yOffset, tooltip,\n    cx = Number(context.getAttribute('cx')),\n    cy = Number(context.getAttribute('cy')),\n    ideo = this;\n\n  if (ideo.config.showAnnotTooltip === false) return;\n\n  clearTimeout(ideo.hideAnnotTooltipTimeout);\n\n  if (ideo.onWillShowAnnotTooltipCallback) {\n    annot = ideo.onWillShowAnnotTooltipCallback(annot);\n  }\n\n  tooltip = d3.select('._ideogramTooltip');\n  tooltip.interrupt(); // Stop any in-progress disapperance\n\n  matrix = context.getScreenCTM().translate(cx, cy);\n\n  [content, yOffset] = getContentAndYOffset(annot);\n\n  writeTooltip(tooltip, content, matrix, yOffset, ideo);\n}\n\nexport {\n  onLoadAnnots, onDrawAnnots, startHideAnnotTooltipTimeout,\n  onWillShowAnnotTooltip, showAnnotTooltip, onClickAnnot\n};\n","/**\n * Get containers to group individual annotations into higher-level \"bar\"\n * annotations.\n */\nfunction getRawBars(chrModels, ideo) {\n  var chr, chrModel, lastBand, numBins, bar, i, px,\n    barWidth = ideo.config.barWidth,\n    bars = [];\n\n  for (chr in chrModels) {\n    chrModel = chrModels[chr];\n    lastBand = chrModel.bands[chrModel.bands.length - 1];\n    numBins = Math.round(lastBand.px.stop / barWidth); // chrPxStop / barWidth\n    bar = {chr: chr, annots: []};\n    for (i = 0; i < numBins; i++) {\n      px = i * barWidth - ideo.bump;\n      bar.annots.push({\n        bp: ideo.convertPxToBp(chrModel, px + ideo.bump),\n        px: px,\n        count: 0,\n        chrIndex: chrModel.chrIndex,\n        chrName: chr,\n        color: ideo.config.annotationsColor,\n        annots: []\n      });\n    }\n    bars.push(bar);\n  }\n  return bars;\n}\n\n/**\n * Assign how many, and which annotations each histogram bar contains\n */\nfunction assignAnnotsToBars(annots, bars, chrModels, ideo) {\n  var chr, chrAnnots, chrModel, barAnnots, i, annot, px, j, barPx, nextBarPx,\n    barWidth = ideo.config.barWidth;\n\n  for (chr in annots) {\n    chrAnnots = annots[chr].annots;\n    chrModel = chrModels[annots[chr].chr]; // get chr by name\n    barAnnots = bars[chrModel.chrIndex].annots;\n    for (i = 0; i < chrAnnots.length; i++) {\n      annot = chrAnnots[i];\n      px = annot.px - ideo.bump;\n      for (j = 0; j < barAnnots.length; j++) {\n        barPx = barAnnots[j].px;\n        nextBarPx = barPx + barWidth;\n        if (j === barAnnots.length - 1) nextBarPx += barWidth;\n        if (px >= barPx && px < nextBarPx) {\n          bars[chrModel.chrIndex].annots[j].count += 1;\n          bars[chrModel.chrIndex].annots[j].annots.push(annot);\n          break;\n        }\n      }\n    }\n  }\n  return bars;\n}\n\nfunction setIdeoMaxAnnotsPerBar(bars, isFirstGet, ideo) {\n  var maxAnnotsPerBarAllChrs, i, maxAnnotsPerBar, annots, chr, j, barCount;\n\n  if (isFirstGet || ideo.config.histogramScaling === 'relative') {\n    maxAnnotsPerBarAllChrs = 0;\n    for (i = 0; i < bars.length; i++) {\n      maxAnnotsPerBar = 0;\n      annots = bars[i].annots;\n      chr = bars[i].chr;\n      for (j = 0; j < annots.length; j++) {\n        barCount = annots[j].count;\n        if (barCount > maxAnnotsPerBar) maxAnnotsPerBar = barCount;\n        if (barCount > maxAnnotsPerBarAllChrs) {\n          maxAnnotsPerBarAllChrs = barCount;\n        }\n      }\n      ideo.maxAnnotsPerBar[chr] = maxAnnotsPerBar;\n    }\n    ideo.maxAnnotsPerBarAllChrs = maxAnnotsPerBarAllChrs;\n  }\n}\n\n/**\n * Set each bar's height to be proportional to the height of the bar with the\n * most annotations\n */\nfunction setProportionalBarHeight(bars, ideo) {\n  var i, annots, chr, j, barCount, barCountRatio, height,\n    ideoIsRotated = ideo._layout._isRotated;\n\n  for (i = 0; i < bars.length; i++) {\n    annots = bars[i].annots;\n    chr = bars[i].chr;\n    for (j = 0; j < annots.length; j++) {\n      barCount = annots[j].count;\n      if (ideo.config.histogramScaling === 'relative') {\n        barCountRatio = barCount / ideo.maxAnnotsPerBar[chr];\n      } else {\n        barCountRatio = barCount / ideo.maxAnnotsPerBarAllChrs;\n      }\n      if (ideoIsRotated === false) {\n        height = barCountRatio * ideo.config.chrMargin;\n      } else {\n        height = barCountRatio * ideo.config.chrHeightOriginal * 3;\n      }\n      if (isNaN(height)) {\n        height = 0;\n      }\n      bars[i].annots[j].height = height;\n    }\n  }\n  return bars;\n}\n\nfunction reportGetHistogramBarPerformance(t0, ideo) {\n  var t1 = new Date().getTime();\n  if (ideo.config.debug) {\n    console.log('Time spent in getHistogramBars: ' + (t1 - t0) + ' ms');\n  }\n}\n\nfunction setIdeoHistogramScaling(ideo) {\n  if ('histogramScaling' in ideo.config === false) {\n    ideo.config.histogramScaling = 'absolute';\n  }\n}\n\n/**\n * Returns and sets bars used for histogram\n */\nfunction getHistogramBars(annots) {\n  var chrModels, bars,\n    isFirstGet = false,\n    t0 = new Date().getTime(),\n    ideo = this;\n\n  chrModels = ideo.chromosomes[ideo.config.taxid];\n\n  setIdeoHistogramScaling(ideo);\n\n  if (typeof ideo.maxAnnotsPerBar === 'undefined') {\n    ideo.maxAnnotsPerBar = {};\n    isFirstGet = true;\n  }\n\n  bars = getRawBars(chrModels, ideo);\n  bars = assignAnnotsToBars(annots, bars, chrModels, ideo);\n  setIdeoMaxAnnotsPerBar(bars, isFirstGet, ideo);\n  bars = setProportionalBarHeight(bars, ideo);\n\n  reportGetHistogramBarPerformance(t0, ideo);\n  ideo.bars = bars;\n  return bars;\n}\n\nfunction getHistogramPoints(d, chrWidth, chrWidths, ideo) {\n  var x1, x2, y1, y2;\n\n  x1 = d.px + ideo.bump;\n  x2 = d.px + ideo.config.barWidth + ideo.bump;\n  y1 = chrWidth;\n  y2 = chrWidth + d.height;\n\n  var thisChrWidth = chrWidths[d.chr];\n\n  if (x2 > thisChrWidth) {\n    x2 = thisChrWidth;\n  }\n\n  return (\n    x1 + ',' + y1 + ' ' +\n    x2 + ',' + y1 + ' ' +\n    x2 + ',' + y2 + ' ' +\n    x1 + ',' + y2\n  );\n}\n\nfunction writeHistogramAnnots(chrAnnot, ideo) {\n  var chrs, chr,\n    chrWidths = {},\n    chrWidth = ideo.config.chrWidth;\n\n  chrs = ideo.chromosomes[ideo.config.taxid];\n  for (chr in chrs) {\n    chrWidths[chr] = chrs[chr];\n  }\n\n  chrAnnot.append('polygon')\n    // .attr('id', function(d, i) { return d.id; })\n    .attr('class', 'annot')\n    .attr('points', function(d) {\n      return getHistogramPoints(d, chrWidth, chrWidths, ideo);\n    })\n    .attr('fill', function(d) {return d.color;});\n}\n\nexport {getHistogramBars, writeHistogramAnnots};\n","/**\n * @fileoverview Functions for drawing a legend for genome annotations.\n * A legend consists of rows, each with a colored icon and a text label.\n * Icons may have different shapes.  A legend may also have a name.\n */\n\nimport {d3} from '../lib';\n\nvar lineHeight = 19;\n\nvar legendStyle =\n  '#_ideogramLegend {font: 12px Arial; line-height: 19px; overflow: auto;} ' +\n  '#_ideogramLegend svg {float: left;} ' +\n  '#_ideogramLegend ul {' +\n    'position: relative; left: -14px; list-style: none; float: left; ' +\n    'padding-left: 10px; margin: 0 0 1em 0; width: auto; border: none;' +\n  '} ' +\n  '#_ideogramLegend li {float: none; margin: 0;}' +\n  '#_ideogramLegend ul span {position: relative; left: -15px;} ';\n\nfunction getIcon(row) {\n  var icon, triangleAttrs, circleAttrs, rectAttrs,\n    fill = 'fill=\"' + row.color + '\" style=\"stroke: #AAA;\"',\n    shape = row.shape;\n\n  triangleAttrs = 'd=\"m7,3 l -5 9 l 9 0 z\"';\n  circleAttrs = 'd=\"m2,9a 4.5,4.5 0 1,0 9,0a 4.5,4.5 0 1,0 -9,0\"';\n  rectAttrs = 'height=\"10\" width=\"10\"  y=\"3\"';\n\n  if ('shape' in row && ['circle', 'triangle'].includes(shape)) {\n    if (shape === 'circle') {\n      icon = '<path ' + circleAttrs + ' ' + fill + '></path>';\n    } else if (shape === 'triangle') {\n      icon = '<path ' + triangleAttrs + ' ' + fill + '></path>';\n    }\n  } else {\n    icon = '<rect ' + rectAttrs + ' ' + fill + '/>';\n  }\n\n  return icon;\n}\n\nfunction getListItems(labels, svg, list) {\n  var i, icon, y, row;\n  for (i = 0; i < list.rows.length; i++) {\n    row = list.rows[i];\n    labels += '<li>' + row.name + '</li>';\n    y = lineHeight * i;\n    if ('name' in list) y += lineHeight;\n    icon = getIcon(row);\n    svg += '<g transform=\"translate(0, ' + y + ')\">' + icon + '</g>';\n  }\n\n  return [labels, svg];\n}\n\n/**\n * Display a legend for genome annotations, using `legend` configuration option\n */\nfunction writeLegend(ideo) {\n  var i, legend, svg, labels, list, content;\n\n  d3.select(ideo.config.container + ' #_ideogramLegend').remove();\n\n  legend = ideo.config.legend;\n  content = '';\n\n  for (i = 0; i < legend.length; i++) {\n    list = legend[i];\n    if ('name' in list) labels = '<span>' + list.name + '</span>';\n    svg = '<svg width=\"' + lineHeight + '\">';\n    [labels, svg] = getListItems(labels, svg, list);\n    svg += '</svg>';\n    content += svg + '<ul>' + labels + '</ul>';\n  }\n\n  var target = d3.select(ideo.config.container + ' #_ideogramOuterWrap');\n  target.append('style').html(legendStyle);\n  target.append('div').attr('id', '_ideogramLegend').html(content);\n}\n\nexport {writeLegend};\n","import {d3} from '../lib';\nimport {writeHistogramAnnots} from './histogram';\nimport {writeLegend} from './legend';\n\nfunction parseFriendlyAnnots(friendlyAnnots, rawAnnots) {\n  var i, j, annot, rawAnnot;\n\n  for (i = 0; i < friendlyAnnots.length; i++) {\n    annot = friendlyAnnots[i];\n\n    for (j = 0; j < rawAnnots.length; j++) {\n      if (annot.chr === rawAnnots[j].chr) {\n        rawAnnot = [\n          annot.name,\n          annot.start,\n          annot.stop - annot.start\n        ];\n        if ('color' in annot) rawAnnot.push(annot.color);\n        if ('shape' in annot) rawAnnot.push(annot.shape);\n        rawAnnots[j].annots.push(rawAnnot);\n        break;\n      }\n    }\n  }\n\n  return rawAnnots;\n}\n\nfunction parseFriendlyKeys(friendlyAnnots) {\n  var keys = ['name', 'start', 'length'];\n  if ('color' in friendlyAnnots[0]) {\n    keys.push('color');\n  }\n  if ('shape' in friendlyAnnots[0]) {\n    keys.push('shape');\n  }\n  return keys;\n}\n\n/**\n * Draws annotations defined by user\n */\nfunction drawAnnots(friendlyAnnots) {\n  var keys, chr,\n    rawAnnots = [],\n    ideo = this,\n    chrs = ideo.chromosomes[ideo.config.taxid]; // TODO: multiorganism\n\n  if (\n    'annots' in friendlyAnnots[0] || // When filtering\n    'values' in friendlyAnnots[0] // When drawing cached expression matrices\n  ) {\n    return ideo.drawProcessedAnnots(friendlyAnnots);\n  }\n\n  for (chr in chrs) {\n    rawAnnots.push({chr: chr, annots: []});\n  }\n  rawAnnots = parseFriendlyAnnots(friendlyAnnots, rawAnnots);\n\n  keys = parseFriendlyKeys(friendlyAnnots);\n\n  ideo.rawAnnots = {keys: keys, annots: rawAnnots};\n  ideo.annots = ideo.processAnnotData(ideo.rawAnnots);\n\n  ideo.drawProcessedAnnots(ideo.annots);\n}\n\nfunction getShapes(annotHeight) {\n  var triangle, circle, rectangle, r;\n\n  triangle =\n    'm0,0 l -' + annotHeight + ' ' + (2 * annotHeight) +\n    ' l ' + (2 * annotHeight) + ' 0 z';\n\n  // From http://stackoverflow.com/a/10477334, with a minor change (\"m -r, r\")\n  // Circles are supported natively via <circle>, but having it as a path\n  // simplifies handling triangles, circles and other shapes in the same\n  // D3 call\n  r = annotHeight;\n  circle =\n    'm -' + r + ', ' + r +\n    'a ' + r + ',' + r + ' 0 1,0 ' + (r * 2) + ',0' +\n    'a ' + r + ',' + r + ' 0 1,0 -' + (r * 2) + ',0';\n\n  rectangle =\n    'm0,0 l 0 ' + (2 * annotHeight) +\n    'l ' + annotHeight + ' 0' +\n    'l 0 -' + (2 * annotHeight) + 'z';\n\n  return {triangle: triangle, circle: circle, rectangle: rectangle};\n}\n\nfunction getChrAnnotNodes(filledAnnots, ideo) {\n  return d3.selectAll(ideo.selector + ' .chromosome')\n    .data(filledAnnots)\n    .selectAll('path.annot')\n    .data(function(d) {\n      return d.annots;\n    })\n    .enter();\n}\n\nfunction determineShape(d, shapes) {\n  if (!d.shape || d.shape === 'triangle') {\n    return shapes.triangle;\n  } else if (d.shape === 'circle') {\n    return shapes.circle;\n  } else if (d.shape === 'rectangle') {\n    return shapes.rectangle;\n  } else {\n    return d.shape;\n  }\n}\n\nfunction writeTrackAnnots(chrAnnot, ideo) {\n  var shapes,\n    annotHeight = ideo.config.annotationHeight;\n\n  shapes = getShapes(annotHeight);\n\n  chrAnnot.append('g')\n    .attr('id', function(d) {return d.id;})\n    .attr('class', 'annot')\n    .attr('transform', function(d) {\n      var y = ideo.config.chrWidth + (d.trackIndex * annotHeight * 2);\n      return 'translate(' + d.px + ',' + y + ')';\n    })\n    .append('path')\n    .attr('d', function(d) {return determineShape(d, shapes);})\n    .attr('fill', function(d) {return d.color;})\n    .on('mouseover', function(d) {ideo.showAnnotTooltip(d, this);})\n    .on('mouseout', function() {ideo.startHideAnnotTooltipTimeout();})\n    .on('click', function(d) {ideo.onClickAnnot(d);});\n}\n\n/**\n * Overlaid annotations appear directly on chromosomes\n */\nfunction writeOverlayAnnots(chrAnnot, ideo) {\n  chrAnnot.append('polygon')\n    .attr('id', function(d) {return d.id;})\n    .attr('class', 'annot')\n    .attr('points', function(d) {\n      var x1, x2,\n        chrWidth = ideo.config.chrWidth;\n\n      if (d.stopPx - d.startPx > 1) {\n        x1 = d.startPx;\n        x2 = d.stopPx;\n      } else {\n        x1 = d.px - 0.5;\n        x2 = d.px + 0.5;\n      }\n\n      return (\n        x1 + ',' + chrWidth + ' ' + x2 + ',' + chrWidth + ' ' +\n        x2 + ',0 ' + x1 + ',0'\n      );\n    })\n    .attr('fill', function(d) {return d.color;})\n    .on('mouseover', function(d) {ideo.showAnnotTooltip(d, this);})\n    .on('mouseout', function() {ideo.startHideAnnotTooltipTimeout();});\n}\n\nfunction warnIfTooManyAnnots(layout, annots) {\n  var i, numAnnots;\n\n  if (!/heatmap/.test(layout) && layout !== 'histogram') {\n    numAnnots = 0;\n    for (i = 0; i < annots.length; i++) {\n      numAnnots += annots[i].annots.length;\n    }\n    if (numAnnots > 2000) {\n      console.warn(\n        'Rendering more than 2000 annotations in Ideogram?\\n' +\n        'Try setting \"annotationsLayout\" to \"heatmap\" or \"histogram\" in your ' +\n        'Ideogram configuration object for better layout and performance.'\n      );\n    }\n  }\n}\n\nfunction drawAnnotsByLayoutType(layout, annots, ideo) {\n  var filledAnnots, chrAnnot;\n\n  warnIfTooManyAnnots(layout, annots);\n\n  if (layout === 'histogram') annots = ideo.getHistogramBars(annots);\n\n  filledAnnots = ideo.fillAnnots(annots);\n\n  chrAnnot = getChrAnnotNodes(filledAnnots, ideo);\n\n  if (layout === 'tracks') {\n    writeTrackAnnots(chrAnnot, ideo);\n  } else if (layout === 'overlay') {\n    writeOverlayAnnots(chrAnnot, ideo);\n  } else if (layout === 'histogram') {\n    writeHistogramAnnots(chrAnnot, ideo);\n  }\n}\n\n/**\n * Draws genome annotations on chromosomes.\n * Annotations can be rendered as either overlaid directly\n * on a chromosome, or along one or more \"tracks\"\n * running parallel to each chromosome.\n */\nfunction drawProcessedAnnots(annots) {\n  var layout,\n    ideo = this;\n\n  d3.selectAll(ideo.selector + ' .annot').remove();\n\n  layout = 'tracks';\n  if (ideo.config.annotationsLayout) layout = ideo.config.annotationsLayout;\n\n  if ('legend' in ideo.config) writeLegend(ideo);\n\n  if (/heatmap/.test(layout)) {\n    ideo.drawHeatmaps(annots);\n    return;\n  }\n\n  drawAnnotsByLayoutType(layout, annots, ideo);\n  if (ideo.onDrawAnnotsCallback) ideo.onDrawAnnotsCallback();\n}\n\nexport {drawAnnots, drawProcessedAnnots};\n","import {d3} from '../lib';\n\nexport function writeSyntenicRegion(syntenies, regionID, ideo) {\n  return syntenies.append('g')\n    .attr('class', 'syntenicRegion')\n    .attr('id', regionID)\n    .on('click', function() {\n      var activeRegion = this;\n      var others = d3.selectAll(ideo.selector + ' .syntenicRegion')\n        .filter(function() {return (this !== activeRegion);});\n\n      others.classed('hidden', !others.classed('hidden'));\n    })\n    .on('mouseover', function() {\n      var activeRegion = this;\n      d3.selectAll(ideo.selector + ' .syntenicRegion')\n        .filter(function() {return (this !== activeRegion);})\n        .classed('ghost', true);\n    })\n    .on('mouseout', function() {\n      d3.selectAll(ideo.selector + ' .syntenicRegion')\n        .classed('ghost', false);\n    });\n}\n\nexport function writeSyntenicRegionPolygons(\n  syntenicRegion, x1, x2, r1, r2, regions\n) {\n  var color, opacity;\n\n  color = ('color' in regions) ? regions.color : '#CFC';\n  opacity = ('opacity' in regions) ? regions.opacity : 1;\n\n  syntenicRegion.append('polygon')\n    .attr('points',\n      x1 + ', ' + r1.startPx + ' ' +\n      x1 + ', ' + r1.stopPx + ' ' +\n      x2 + ', ' + r2.stopPx + ' ' +\n      x2 + ', ' + r2.startPx\n    )\n    .style('fill', color)\n    .style('fill-opacity', opacity);\n}\n\nexport function writeSyntenicRegionPolygonsHorizontal(\n  syntenicRegion, y1, y2, r1, r2, regions\n) {\n  var color, opacity;\n\n  color = ('color' in regions) ? regions.color : '#CFC';\n  opacity = ('opacity' in regions) ? regions.opacity : 1;\n\n  syntenicRegion.append('polygon')\n    .attr('points',\n      (r1.startPx - 15) + ', ' + y1 + ' ' +\n      (r1.stopPx - 15) + ', ' + y1 + ' ' +\n      (r2.stopPx - 15) + ', ' + y2 + ' ' +\n      (r2.startPx - 15) + ', ' + y2\n    )\n    .style('fill', color)\n    .style('fill-opacity', opacity);\n}\n\nexport function getRegionsR1AndR2(regions, ideo, xOffset = null) {\n  var r1, r2,\n    r1Offset, r2Offset;\n\n  r1 = regions.r1;\n  r2 = regions.r2;\n\n  if (typeof r1.chr === 'string') {\n    const taxids = ideo.config.taxids;\n    if (ideo.config.multiorganism) {\n      r1.chr = ideo.chromosomes[taxids[0]][r1.chr];\n      r2.chr = ideo.chromosomes[taxids[1]][r2.chr];\n    } else {\n      r1.chr = ideo.chromosomes[taxids[0]][r1.chr];\n      r2.chr = ideo.chromosomes[taxids[0]][r2.chr];\n    }\n  }\n\n  var r1ChrDom = document.querySelector('#' + r1.chr.id + '-chromosome-set');\n  var r1GenomeHorizontalXOffset = r1ChrDom.getCTM().e;\n  var r1GenomeVerticalXOffset = r1ChrDom.getCTM().f;\n  var r2ChrDom = document.querySelector('#' + r2.chr.id + '-chromosome-set');\n  // var r2GenomeOffset = r2ChrDom.getBoundingClientRect().top;\n  var r2GenomeHorizontalXOffset = r2ChrDom.getCTM().e;\n  var r2GenomeVerticalXOffset = r2ChrDom.getCTM().f;\n\n  if (xOffset === null) {\n    if (ideo.config.orientation === 'vertical') {\n      // When vertical collinear\n      // http://localhost:8080/examples/vanilla/compare-whole-genomes?chromosome-scale=absolute&orientation=vertical\n      r1Offset = r1GenomeVerticalXOffset - 12;\n      r2Offset = r2GenomeVerticalXOffset - 12;\n    } else {\n      // When horizontal collinear, e.g.\n      // http://localhost:8080/examples/vanilla/compare-whole-genomes?chromosome-scale=absolute&orientation=horizontal\n      r1Offset = r1GenomeHorizontalXOffset;\n      r2Offset = r2GenomeHorizontalXOffset;\n    }\n  } else {\n    // When horizontal parallel\n    r1Offset = xOffset;\n    r2Offset = xOffset;\n  }\n\n  r1.startPx = ideo.convertBpToPx(r1.chr, r1.start) + r1Offset;\n  r1.stopPx = ideo.convertBpToPx(r1.chr, r1.stop) + r1Offset;\n  r2.startPx = ideo.convertBpToPx(r2.chr, r2.start) + r2Offset;\n  r2.stopPx = ideo.convertBpToPx(r2.chr, r2.stop) + r2Offset;\n\n  return [r1, r2];\n}\n","import {d3} from '../lib';\nimport {\n  getRegionsR1AndR2, writeSyntenicRegionPolygons, writeSyntenicRegion\n} from './synteny-lib';\n\nfunction writeSyntenicRegionLines(syntenicRegion, x1, x2, r1, r2) {\n  syntenicRegion.append('line')\n    .attr('class', 'syntenyBorder')\n    .attr('x1', x1)\n    .attr('x2', x2)\n    .attr('y1', r1.startPx)\n    .attr('y2', r2.startPx);\n\n  syntenicRegion.append('line')\n    .attr('class', 'syntenyBorder')\n    .attr('x1', x1)\n    .attr('x2', x2)\n    .attr('y1', r1.stopPx)\n    .attr('y2', r2.stopPx);\n}\n\nfunction writeSyntenicRegions(syntenicRegions, syntenies, ideo) {\n  var i, regions, r1, r2, regionID, syntenicRegion, chrWidth, x1, x2;\n\n  for (i = 0; i < syntenicRegions.length; i++) {\n    regions = syntenicRegions[i];\n\n    [r1, r2] = getRegionsR1AndR2(regions, ideo);\n\n    regionID = (\n      r1.chr.id + '_' + r1.start + '_' + r1.stop + '_' +\n      '__' +\n      r2.chr.id + '_' + r2.start + '_' + r2.stop\n    );\n\n    syntenicRegion = writeSyntenicRegion(syntenies, regionID, ideo);\n\n    chrWidth = ideo.config.chrWidth;\n    x1 = chrWidth + 46;\n    x2 = chrWidth + 240; // Genomes are spaced ~200 pixels apart\n\n    writeSyntenicRegionPolygons(syntenicRegion, x1, x2, r1, r2, regions);\n    writeSyntenicRegionLines(syntenicRegion, x1, x2, r1, r2);\n  }\n}\n\nfunction reportPerformance(t0, ideo) {\n  var t1 = new Date().getTime();\n  if (ideo.config.debug) {\n    console.log('Time in drawSyntenicRegions: ' + (t1 - t0) + ' ms');\n  }\n}\n\n/**\n * Draws a trapezoid connecting a genomic range on\n * one chromosome to a genomic range on another chromosome;\n * a syntenic region.\n */\nfunction drawSyntenyCollinear(syntenicRegions, ideo) {\n  var syntenies,\n    t0 = new Date().getTime();\n\n  syntenies = d3.select(ideo.selector)\n    .insert('g', ':first-child')\n    .attr('class', 'synteny');\n\n  writeSyntenicRegions(syntenicRegions, syntenies, ideo);\n\n  reportPerformance(t0, ideo);\n}\n\nexport {drawSyntenyCollinear};\n","import {d3} from '../lib';\nimport {\n  getRegionsR1AndR2, writeSyntenicRegionPolygonsHorizontal, writeSyntenicRegion\n} from './synteny-lib';\n\nfunction writeSyntenicRegionLines(syntenicRegion, y1, y2, r1, r2) {\n  syntenicRegion.append('line')\n    .attr('class', 'syntenyBorder')\n    .attr('x1', r1.startPx - 15)\n    .attr('x2', r2.startPx - 15)\n    .attr('y1', y1)\n    .attr('y2', y2);\n\n  syntenicRegion.append('line')\n    .attr('class', 'syntenyBorder')\n    .attr('x1', r1.stopPx - 15)\n    .attr('x2', r2.stopPx - 15)\n    .attr('y1', y1)\n    .attr('y2', y2);\n}\n\nfunction writeSyntenicRegions(syntenicRegions, syntenies, ideo) {\n  var i, regions, r1, r2, regionID, syntenicRegion, chrWidth, y1, y2;\n\n  for (i = 0; i < syntenicRegions.length; i++) {\n    regions = syntenicRegions[i];\n\n    [r1, r2] = getRegionsR1AndR2(regions, ideo);\n\n    regionID = (\n      r1.chr.id + '_' + r1.start + '_' + r1.stop + '_' +\n      '__' +\n      r2.chr.id + '_' + r2.start + '_' + r2.stop\n    );\n\n    syntenicRegion = writeSyntenicRegion(syntenies, regionID, ideo);\n\n    chrWidth = ideo.config.chrWidth;\n    y1 = chrWidth + 31;\n    y2 = chrWidth + 191; // Genomes are spaced ~200 pixels apart\n\n    writeSyntenicRegionPolygonsHorizontal(\n      syntenicRegion, y1, y2, r1, r2, regions\n    );\n    writeSyntenicRegionLines(syntenicRegion, y1, y2, r1, r2);\n  }\n}\n\nfunction reportPerformance(t0, ideo) {\n  var t1 = new Date().getTime();\n  if (ideo.config.debug) {\n    console.log('Time in drawSyntenicRegions: ' + (t1 - t0) + ' ms');\n  }\n}\n\n/**\n * Draws a trapezoid connecting a genomic range on\n * one chromosome to a genomic range on another chromosome;\n * a syntenic region.\n */\nfunction drawSyntenyCollinearHorizontal(syntenicRegions, ideo) {\n  var syntenies,\n    t0 = new Date().getTime();\n\n  syntenies = d3.select(ideo.selector)\n    .insert('g', ':first-child')\n    .attr('class', 'synteny');\n\n  writeSyntenicRegions(syntenicRegions, syntenies, ideo);\n\n  reportPerformance(t0, ideo);\n}\n\nexport {drawSyntenyCollinearHorizontal};\n","import {d3} from '../lib';\nimport {drawSyntenyCollinear} from './synteny-collinear';\nimport {drawSyntenyCollinearHorizontal} from './synteny-collinear-horizontal';\nimport {\n  getRegionsR1AndR2, writeSyntenicRegionPolygons, writeSyntenicRegion\n} from './synteny-lib';\n\nfunction writeSyntenicRegionLines(syntenicRegion, x1, x2, r1, r2, regions) {\n\n  var stroke, width;\n  if (\n    Math.abs(r1.startPx - r1.startPx) < 2 &&\n    Math.abs(r1.stopPx - r1.stopPx) < 2\n  ) {\n    stroke = regions.color;\n    width = regions.width;\n  } else {\n    stroke = '';\n    width = '';\n  }\n\n  syntenicRegion.append('line')\n    .attr('class', 'syntenyBorder')\n    .attr('x1', x1)\n    .attr('x2', x2)\n    .attr('y1', r1.startPx)\n    .attr('y2', r2.startPx)\n    .style('stroke', stroke)\n    .style('stroke-width', width);\n\n  syntenicRegion.append('line')\n    .attr('class', 'syntenyBorder')\n    .attr('x1', x1)\n    .attr('x2', x2)\n    .attr('y1', r1.stopPx)\n    .attr('y2', r2.stopPx)\n    .style('stroke', stroke)\n    .style('stroke-width', stroke);\n}\n\nfunction writeSyntenicRegionLabels(syntenicRegion, x1, x2, r1, r2, regionId) {\n  var rangeIds = regionId.split('__').map(d => 'label_' + d);\n  if ('name' in r1) {\n    syntenicRegion.append('text')\n      .attr('id', rangeIds[0])\n      .attr('y', r1.startPx + 3)\n      .text(r1.name);\n    var r1Width =\n      document.querySelector('#' + rangeIds[0]).getBoundingClientRect().width;\n    d3.select('#' + rangeIds[0]).attr('x', x1 - 15 - r1Width);\n  }\n  if ('name' in r2) {\n    syntenicRegion.append('text')\n      .attr('id', rangeIds[1])\n      .text(r2.name)\n      .attr('x', x2 + 15)\n      .attr('y', r2.startPx + 3)\n      .text(r2.name);\n  }\n}\n\nfunction writeSyntenicRegions(syntenicRegions, syntenies, xOffset, ideo) {\n  var i, regions, r1, r2, regionID, syntenicRegion, chrWidth, x1, x2;\n\n  for (i = 0; i < syntenicRegions.length; i++) {\n    regions = syntenicRegions[i];\n\n    [r1, r2] = getRegionsR1AndR2(regions, ideo, xOffset);\n\n    regionID = (\n      r1.chr.id + '_' + r1.start + '_' + r1.stop + '_' +\n      '__' +\n      r2.chr.id + '_' + r2.start + '_' + r2.stop\n    );\n\n    syntenicRegion = writeSyntenicRegion(syntenies, regionID, ideo);\n\n    chrWidth = ideo.config.chrWidth;\n    x1 = ideo._layout.getChromosomeSetYTranslate(0);\n    x2 = ideo._layout.getChromosomeSetYTranslate(1) - chrWidth;\n\n    writeSyntenicRegionPolygons(syntenicRegion, x1, x2, r1, r2, regions);\n    writeSyntenicRegionLines(syntenicRegion, x1, x2, r1, r2, regions);\n    writeSyntenicRegionLabels(syntenicRegion, x1, x2, r1, r2, regionID);\n  }\n}\n\nfunction reportPerformance(t0, ideo) {\n  var t1 = new Date().getTime();\n  if (ideo.config.debug) {\n    console.log('Time in drawSyntenicRegions: ' + (t1 - t0) + ' ms');\n  }\n}\n\n/**\n * Draws a trapezoid connecting a genomic range on\n * one chromosome to a genomic range on another chromosome;\n * a syntenic region.\n */\nfunction drawSynteny(syntenicRegions) {\n  var syntenies, xOffset,\n    t0 = new Date().getTime(),\n    ideo = this,\n    config = ideo.config;\n\n  if (\n    config.multiorganism &&\n    config.geometry === 'collinear'\n  ) {\n    if (config.orientation === 'vertical') {\n      return drawSyntenyCollinear(syntenicRegions, ideo);\n    } else {\n      return drawSyntenyCollinearHorizontal(syntenicRegions, ideo);\n    }\n  }\n\n  syntenies = d3.select(ideo.selector)\n    .insert('g', ':first-child')\n    .attr('class', 'synteny');\n\n  xOffset = ideo._layout.margin.left;\n\n  writeSyntenicRegions(syntenicRegions, syntenies, xOffset, ideo);\n\n  reportPerformance(t0, ideo);\n}\n\nexport {drawSynteny};\n","import {d3} from '../lib';\nimport collinearizeChromosomes from '../collinear';\n\n/**\n * Reset displayed tracks to those originally displayed\n */\nfunction restoreDefaultTracks() {\n  var ideo = this;\n  ideo.config.numAnnotTracks = ideo.config.annotationsNumTracks;\n  d3.selectAll(ideo.selector + ' .annot').remove();\n  ideo.drawAnnots(ideo.processAnnotData(ideo.rawAnnots));\n}\n\nfunction getDisplayedRawAnnotsByChr(annotsByChr, trackIndexes) {\n  var annot, displayedRawAnnotsByChr, annots, i, displayedAnnots, j,\n    trackIndex;\n\n  displayedRawAnnotsByChr = [];\n\n  // Filter displayed tracks by selected track indexes\n  for (i = 0; i < annotsByChr.length; i++) {\n    annots = annotsByChr[i];\n    displayedAnnots = [];\n    for (j = 0; j < annots.annots.length; j++) {\n      annot = annots.annots[j].slice(); // copy array by value\n      trackIndex = annot[3] + 1;\n      if (trackIndexes.includes(trackIndex)) {\n        annot[3] = trackIndexes.indexOf(trackIndex);\n        displayedAnnots.push(annot);\n      }\n    }\n    displayedRawAnnotsByChr.push({chr: annots.chr, annots: displayedAnnots});\n  }\n\n  return displayedRawAnnotsByChr;\n}\n\n/**\n * Adds or removes tracks from the displayed list of tracks.\n * Only works when raw annotations are dense.\n *\n * @param trackIndexes Array of indexes of tracks to display\n */\nfunction updateDisplayedTracks(trackIndexes) {\n  var displayedRawAnnotsByChr, displayedAnnots, rawAnnots,\n    ideo = this,\n    annotsByChr = ideo.rawAnnots.annots;\n\n  ideo.config.numAnnotTracks = trackIndexes.length;\n\n  displayedRawAnnotsByChr =\n    getDisplayedRawAnnotsByChr(annotsByChr, trackIndexes);\n  rawAnnots = {keys: ideo.rawAnnots.keys, annots: displayedRawAnnotsByChr};\n\n  if (ideo.config.geometry === 'collinear') {\n    collinearizeChromosomes(ideo);\n  }\n\n  displayedAnnots = ideo.processAnnotData(rawAnnots);\n\n  d3.selectAll(ideo.selector + ' .annot').remove();\n  ideo.displayedTrackIndexes = trackIndexes;\n  ideo.drawAnnots(displayedAnnots);\n\n  return displayedAnnots;\n}\n\nfunction getSetAnnotsByChr(annotsByChr, ideo) {\n  var i, j, annots, annot, setAnnots, trackIndexOriginal, numAvailTracks,\n    setAnnotsByChr = [];\n\n  numAvailTracks = 1;\n\n  for (i = 0; i < annotsByChr.length; i++) {\n    annots = annotsByChr[i];\n    setAnnots = [];\n    for (j = 0; j < annots.annots.length; j++) {\n      annot = annots.annots[j].slice();\n      trackIndexOriginal = annot[3];\n      if (trackIndexOriginal + 1 > numAvailTracks) {\n        numAvailTracks = trackIndexOriginal + 1;\n      }\n      annot.splice(4, 0, trackIndexOriginal);\n      setAnnots.push(annot);\n    }\n    setAnnotsByChr.push({chr: annots.chr, annots: setAnnots});\n  }\n\n  ideo.numAvailTracks = numAvailTracks;\n\n  return setAnnotsByChr;\n}\n\nfunction setOriginalTrackIndexes(rawAnnots) {\n  var keys, annotsByChr, setAnnotsByChr,\n    ideo = this;\n\n  keys = rawAnnots.keys;\n\n  // If this method is unnecessary, pass through\n  if (\n    keys.length < 4 ||\n    keys[3] !== 'trackIndex' ||\n    keys[4] === 'trackIndexOriginal'\n  ) {\n    return rawAnnots;\n  }\n\n  annotsByChr = rawAnnots.annots;\n  setAnnotsByChr = getSetAnnotsByChr(annotsByChr, ideo);\n\n  keys.splice(4, 0, 'trackIndexOriginal');\n  rawAnnots = {keys: keys, annots: setAnnotsByChr};\n  if (ideo.rawAnnots.metadata) rawAnnots.metadata = ideo.rawAnnots.metadata;\n\n  return rawAnnots;\n}\n\nexport {restoreDefaultTracks, setOriginalTrackIndexes, updateDisplayedTracks};\n","import {add2dAnnotsForChr} from './heatmap-2d';\n\n// Default colors for tracks of annotations\nvar colorMap = [\n  ['F00'], // If there is 1 track, then color it red.\n  ['F00', '88F'], // If 2 tracks, color one red and one light blue.\n  ['F00', 'CCC', '88F'], // If 3, color one red, one grey, one light blue.\n  ['F00', 'FA0', '0AF', '88F'], // And so on.\n  ['F00', 'FA0', 'CCC', '0AF', '88F'],\n  ['F00', 'FA0', '875', '578', '0AF', '88F'],\n  ['F00', 'FA0', '875', 'CCC', '578', '0AF', '88F'],\n  ['F00', 'FA0', '7A0', '875', '0A7', '578', '0AF', '88F'],\n  ['F00', 'FA0', '7A0', '875', 'CCC', '0A7', '578', '0AF', '88F'],\n  ['F00', 'FA0', '7A0', '875', '552', '255', '0A7', '578', '0AF', '88F']\n];\n\n/**\n * Ensure annotation containers are ordered by chromosome.\n */\nfunction orderAnnotContainers(annots, ideo) {\n  var unorderedAnnots, i, j, annot, chr, chrs;\n\n  unorderedAnnots = annots;\n  annots = [];\n  chrs = ideo.chromosomesArray;\n  for (i = 0; i < chrs.length; i++) {\n    chr = chrs[i].name;\n    for (j = 0; j < unorderedAnnots.length; j++) {\n      annot = unorderedAnnots[j];\n      if (annot.chr === chr) {\n        annots.push(annot);\n      }\n    }\n  }\n\n  return annots;\n}\n\n/**\n * Add client annotations, as in annotations-tracks.html\n */\nfunction addClientAnnot(annots, annot, ra, m, ideo) {\n  var annotTrack;\n\n  annot.trackIndex = ra[3];\n  annotTrack = ideo.config.annotationTracks[annot.trackIndex];\n  if (annotTrack.color) {\n    annot.color = annotTrack.color;\n  }\n  if (annotTrack.shape) {\n    annot.shape = annotTrack.shape;\n  }\n\n  annots[m].annots.push(annot);\n\n  return annots;\n}\n\n/**\n * Add sparse server annotations, as in annotations-track-filters.html\n */\nfunction addSparseServerAnnot(annot, ra, omittedAnnots, annots, m, ideo) {\n  var colors = colorMap[ideo.numAvailTracks - 1];\n\n  annot.trackIndex = ra[3];\n  annot.trackIndexOriginal = ra[4];\n  annot.color = '#' + colors[annot.trackIndexOriginal];\n\n  // Catch annots that will be omitted from display\n  if (annot.trackIndex > ideo.config.numTracks - 1) {\n    if (annot.trackIndex in omittedAnnots) {\n      omittedAnnots[annot.trackIndex].push(annot);\n    } else {\n      omittedAnnots[annot.trackIndex] = [annot];\n    }\n    return [annots, omittedAnnots];\n  }\n  annots[m].annots.push(annot);\n\n  return [annots, omittedAnnots];\n}\n\n/**\n * Basic client annotations, as in annotations-basic.html\n * and annotations-external.html\n */\nfunction addBasicClientAnnot(annots, annot, m, ideo) {\n  annot.trackIndex = 0;\n  if (!annot.color) {\n    annot.color = ideo.config.annotationsColor;\n  }\n  if (!annot.shape) {\n    annot.shape = 'triangle';\n  }\n  annots[m].annots.push(annot);\n\n  return annots;\n}\n\nfunction addAnnot(annot, keys, ra, omittedAnnots, annots, m, ideo) {\n\n  if (ideo.config.annotationTracks) {\n    annots = addClientAnnot(annots, annot, ra, m, ideo);\n  } else if (keys[3] === 'trackIndex' && ideo.numAvailTracks !== 1) {\n    [annots, omittedAnnots] =\n      addSparseServerAnnot(annot, ra, omittedAnnots, annots, m, ideo);\n  // } else if (\n  //   keys.length > 3 &&\n  //   keys[3] in {trackIndex: 1, color: 1, shape: 1} === false &&\n  //   keys[4] === 'trackIndexOriginal'\n  // ) {\n  //   annots = addDenseServerAnnot(keys, annots, annot, m);\n  } else {\n    annots = addBasicClientAnnot(annots, annot, m, ideo);\n  }\n\n  return [annots, omittedAnnots];\n}\n\nfunction addAnnotsForChr(annots, omittedAnnots, annotsByChr, chrModel,\n  m, keys, ideo) {\n  var j, k, annot, ra;\n\n  for (j = 0; j < annotsByChr.annots.length; j++) {\n    ra = annotsByChr.annots[j];\n    annot = {};\n\n    for (k = 0; k < keys.length; k++) {\n      annot[keys[k]] = ra[k];\n    }\n\n    annot.stop = annot.start + annot.length;\n\n    annot.chr = annotsByChr.chr;\n    annot.chrIndex = m;\n    annot.startPx = ideo.convertBpToPx(chrModel, annot.start);\n    annot.stopPx = ideo.convertBpToPx(chrModel, annot.stop);\n    annot.px = Math.round((annot.startPx + annot.stopPx) / 2);\n\n    [annots, omittedAnnots] =\n      addAnnot(annot, keys, ra, omittedAnnots, annots, m, ideo);\n  }\n\n  return [annots, omittedAnnots];\n}\n\nfunction warnOfUndefinedChromosome(annotsByChr) {\n  console.warn(\n    'Chromosome \"' + annotsByChr.chr + '\" undefined in ideogram; ' +\n    annotsByChr.annots.length + ' annotations not shown'\n  );\n}\n\nfunction addAnnots(rawAnnots, keys, ideo) {\n  var m, i, annotsByChr, chrModel,\n    annots = [],\n    omittedAnnots = {};\n\n  m = -1;\n  for (i = 0; i < rawAnnots.length; i++) {\n    annotsByChr = rawAnnots[i];\n    chrModel = ideo.chromosomes[ideo.config.taxid][annotsByChr.chr];\n\n    if (typeof chrModel === 'undefined') {\n      warnOfUndefinedChromosome(annotsByChr);\n      continue;\n    }\n\n    m++;\n    annots.push({chr: annotsByChr.chr, annots: []});\n\n    if (ideo.config.annotationsLayout !== 'heatmap-2d') {\n      [annots, omittedAnnots] =\n        addAnnotsForChr(annots, omittedAnnots, annotsByChr, chrModel, m,\n          keys, ideo);\n    } else {\n      [annots, omittedAnnots] =\n        add2dAnnotsForChr(annots, omittedAnnots, annotsByChr, chrModel, m,\n          keys, ideo);\n    }\n  }\n  return [annots, omittedAnnots];\n}\n\nfunction sendTrackAndAnnotWarnings(omittedAnnots, ideo) {\n  var numOmittedTracks,\n    layout = ideo.config.annotationsLayout,\n    numTracks = ideo.config.numAnnotTracks;\n\n  if (!/heatmap/.test(layout) && numTracks > 10) {\n    console.error(\n      'Ideogram only displays up to 10 tracks at a time.  ' +\n      'You specified ' + numTracks + ' tracks.  ' +\n      'Perhaps consider a different way to visualize your data.'\n    );\n  }\n\n  numOmittedTracks = Object.keys(omittedAnnots).length;\n  if (numOmittedTracks) {\n    console.warn(\n      'Ideogram configuration specified ' + numTracks + ' tracks, ' +\n      'but loaded annotations contain ' + numOmittedTracks + ' ' +\n      'extra tracks.'\n    );\n  }\n}\n\n/**\n * Proccesses genome annotation data.\n *\n * This method converts raw annotation data from server, which is structured as\n * an array of arrays, into a more verbose data structure consisting of an\n * array of objects.  It also adds pixel offset information.\n */\nfunction processAnnotData(rawAnnots) {\n  var keys, annots, omittedAnnots,\n    ideo = this;\n\n  keys = rawAnnots.keys;\n  rawAnnots = rawAnnots.annots;\n\n  [annots, omittedAnnots] = addAnnots(rawAnnots, keys, ideo);\n  annots = orderAnnotContainers(annots, ideo);\n\n  sendTrackAndAnnotWarnings(omittedAnnots, ideo);\n\n  return annots;\n}\n\nexport {processAnnotData};\n","/**\n * @fileoverview Parse raw Ideogram.js annotations from an expression matrix.\n * This module handles dense gene expression matrixes.\n * In gene expression expressions, rows are genes and columns are cells.\n */\n\nexport class ExpressionMatrixParser {\n\n  /**\n   * @param {String} matrix Tab-delimited gene expression matrix\n   * @param {Object} coordinates Coordinates [chr, start, length] by gene name\n   * @param {Object} ideo Ideogram object\n   */\n  constructor(matrix, ideo) {\n    this.matrix = matrix;\n    this.ideo = ideo;\n  }\n\n  /**\n   * Initialize rawAnnots by fetching genomic coordinates, then merging them\n   * with the gene expression matrix supplied in constructor.\n   */\n  setRawAnnots() {\n    var parser, ideo, matrix;\n    parser = this;\n    ideo = this.ideo;\n    matrix = this.matrix;\n\n    return new Promise(function(resolve) {\n      parser.rawAnnots = parser.fetchCoordinates(ideo)\n        .then(function(coordinates) {\n          parser.coordinates = coordinates;\n          resolve(parser.parseExpressionMatrix(matrix, ideo));\n        });\n    });\n  }\n\n  /**\n   * Get chromosome, start and stop coordinates from genome annotation file\n   *\n   * TODO: Support non-human organisms\n   */\n  fetchCoordinates(ideo) {\n    var coordinates = {};\n\n    if (ideo.config.organism === 'human') {\n      var ensemblData =\n        ideo.config.dataDir +\n        '../../annotations/Homo_sapiens,_Ensembl_80.tsv';\n\n      return new Promise(function(resolve) {\n        ideo.fetch(ensemblData, 'text').then(function(data) {\n          // eslint-disable-next-line no-unused-vars\n          var tsvLines, i, start, stop, gene, chr, length, geneType;\n\n          tsvLines = data.split(/\\r\\n|\\n/).slice(1);\n          for (i = 0; i < tsvLines.length; i++) {\n            [start, stop, gene, geneType, chr] = tsvLines[i].split(/\\s/g);\n            start = parseInt(start);\n            stop = parseInt(stop);\n            length = stop - start;\n            coordinates[gene] = [chr, start, length];\n          }\n          resolve(coordinates);\n        });\n      });\n    } else {\n      throw Error('Expression matrix parsing is only supported for human');\n    }\n  }\n\n  /**\n   * Parses an annotation from a tab-separated line of a matrix file\n   */\n  parseAnnotFromTsvLine(tsvLine, chrs) {\n    var annot, chrIndex, chr, start, gene, expressions,\n      columns = tsvLine.split(/\\s/g);\n\n    gene = columns[0];\n    if (gene in this.coordinates === false) return [null, null];\n\n    expressions = columns.slice(1).map(d => parseFloat(d));\n    [chr, start, length] = this.coordinates[gene];\n\n    chrIndex = chrs.indexOf(chr);\n    if (chrIndex === -1) return [null, null];\n\n    annot = [gene, start, length];\n    annot = annot.concat(expressions);\n\n    return [chrIndex, annot];\n  }\n\n  /**\n  * Parses a gene expression matrix file, returns raw annotations\n  */\n  parseExpressionMatrix(matrix, ideo) {\n    var i, chrs, rawAnnots, cells, line, chrIndex, annot, keys,\n      annots = [],\n      tsvLines = matrix.split(/\\r\\n|\\n/);\n\n    chrs = Object.keys(ideo.chromosomes[ideo.config.taxid]);\n    for (i = 0; i < chrs.length; i++) {\n      annots.push({chr: chrs[i], annots: []});\n    }\n\n    for (i = 1; i < tsvLines.length; i++) {\n      line = tsvLines[i];\n      [chrIndex, annot] = this.parseAnnotFromTsvLine(line, chrs);\n      if (chrIndex !== null) annots[chrIndex].annots.push(annot);\n    }\n\n    cells = tsvLines[0].split(/\\s/g);\n    keys = ['name', 'start', 'length'].concat(cells);\n    rawAnnots = {keys: keys, annots: annots};\n\n    return rawAnnots;\n  }\n\n}\n","/**\n * @fileoverview Methods for ideogram annotations.\n * Annotations are graphical objects that represent features of interest\n * located on the chromosomes, e.g. genes or variations.  They can\n * appear beside a chromosome, overlaid on top of it, or between multiple\n * chromosomes.\n */\n\nimport {BedParser} from '../parsers/bed-parser';\nimport {drawHeatmaps, deserializeAnnotsForHeatmap} from './heatmap';\nimport {inflateThresholds} from './heatmap-lib';\nimport {inflateHeatmaps} from './heatmap-collinear';\nimport {\n  onLoadAnnots, onDrawAnnots, startHideAnnotTooltipTimeout,\n  onWillShowAnnotTooltip, showAnnotTooltip, onClickAnnot\n} from './events';\nimport {drawAnnots, drawProcessedAnnots} from './draw';\nimport {getHistogramBars} from './histogram';\nimport {drawSynteny} from './synteny';\nimport {\n  restoreDefaultTracks, setOriginalTrackIndexes, updateDisplayedTracks\n} from './filter';\nimport {processAnnotData} from './process';\nimport {ExpressionMatrixParser} from '../parsers/expression-matrix-parser';\n\nfunction initNumTracksAndBarWidth(ideo, config) {\n\n  if (config.annotationTracks) {\n    ideo.config.numAnnotTracks = config.annotationTracks.length;\n  } else if (config.annotationsNumTracks) {\n    ideo.config.numAnnotTracks = config.annotationsNumTracks;\n  } else {\n    ideo.config.numAnnotTracks = 1;\n  }\n  ideo.config.annotTracksHeight =\n    config.annotationHeight * config.numAnnotTracks;\n\n  if (typeof config.barWidth === 'undefined') {\n    ideo.config.barWidth = 3;\n  }\n}\n\nfunction initTooltip(ideo, config) {\n  if (config.showAnnotTooltip !== false) {\n    ideo.config.showAnnotTooltip = true;\n  }\n\n  if (config.onWillShowAnnotTooltip) {\n    ideo.onWillShowAnnotTooltipCallback = config.onWillShowAnnotTooltip;\n  }\n}\n\nfunction initAnnotHeight(ideo) {\n  var config = ideo.config;\n  var annotHeight;\n\n  if (!config.annotationHeight) {\n    if (config.annotationsLayout === 'heatmap') {\n      annotHeight = config.chrWidth - 1;\n    } else {\n      annotHeight = Math.round(config.chrHeight / 100);\n      if (annotHeight < 3) annotHeight = 3;\n    }\n    ideo.config.annotationHeight = annotHeight;\n  }\n}\n\n/**\n * Initializes various annotation settings.  Constructor help function.\n */\nfunction initAnnotSettings() {\n  var ideo = this,\n    config = ideo.config;\n\n  initAnnotHeight(ideo);\n\n  if (\n    config.annotationsPath || config.localAnnotationsPath ||\n    ideo.annots || config.annotations\n  ) {\n    initNumTracksAndBarWidth(ideo, config);\n  } else {\n    ideo.config.annotTracksHeight = 0;\n    ideo.config.numAnnotTracks = 0;\n  }\n\n  if (typeof config.annotationsColor === 'undefined') {\n    ideo.config.annotationsColor = '#F00';\n  }\n\n  if (config.onClickAnnot) {\n    ideo.onClickAnnotCallback = config.onClickAnnot;\n  }\n\n  initTooltip(ideo, config);\n}\n\nfunction validateAnnotsUrl(annotsUrl) {\n  var tmp, extension;\n\n  tmp = annotsUrl.split('?')[0].split('.');\n  extension = tmp[tmp.length - 1];\n\n  if (extension !== 'bed' && extension !== 'json') {\n    extension = extension.toUpperCase();\n    alert(\n      'Ideogram.js only supports BED and Ideogram JSON at the moment.  ' +\n      'Sorry, check back soon for ' + extension + ' support!'\n    );\n    return;\n  }\n  return extension;\n}\n\nfunction afterRawAnnots() {\n  var ideo = this,\n    config = ideo.config;\n  // Ensure annots are ordered by chromosome\n  ideo.rawAnnots.annots = ideo.rawAnnots.annots.sort(function(a, b) {\n    return a.chr.localeCompare(b.chr, 'en', {numeric: true});\n  });\n\n  if (ideo.onLoadAnnotsCallback) {\n    ideo.onLoadAnnotsCallback();\n  }\n\n  if (\n    'heatmapThresholds' in config ||\n    'metadata' in ideo.rawAnnots &&\n    'heatmapThresholds' in ideo.rawAnnots.metadata\n  ) {\n    if (config.annotationsLayout === 'heatmap') {\n      inflateHeatmaps(ideo);\n    } else if (config.annotationsLayout === 'heatmap-2d') {\n      ideo.config.heatmapThresholds = inflateThresholds(ideo);\n    }\n  }\n\n  if (config.heatmaps) {\n    ideo.deserializeAnnotsForHeatmap(ideo.rawAnnots);\n  }\n}\n\n/**\n * Requests annotations URL via HTTP, sets ideo.rawAnnots for downstream\n * processing.\n *\n * @param annotsUrl Absolute or relative URL for native or BED annotations file\n */\nfunction fetchAnnots(annotsUrl) {\n  var extension, is2dHeatmap,\n    ideo = this,\n    config = ideo.config;\n\n  is2dHeatmap = config.annotationsLayout === 'heatmap-2d';\n\n  if (annotsUrl.slice(0, 4) !== 'http' && !is2dHeatmap) {\n    ideo.fetch(annotsUrl)\n      .then(function(data) {\n        ideo.rawAnnotsResponse = data; // Preserve truly raw response content\n        ideo.rawAnnots = data; // Sometimes gets partially processed\n        ideo.afterRawAnnots();\n      });\n    return;\n  }\n\n  extension = (is2dHeatmap ? '' : validateAnnotsUrl(annotsUrl));\n\n  ideo.fetch(annotsUrl, 'text')\n    .then(function(text) {\n      ideo.rawAnnotsResponse = text;\n      if (is2dHeatmap) {\n        var parser = new ExpressionMatrixParser(text, ideo);\n        parser.setRawAnnots().then(function(d) {\n          ideo.rawAnnots = d;\n          ideo.afterRawAnnots();\n        });\n      } else {\n        if (extension === 'bed') {\n          ideo.rawAnnots = new BedParser(text, ideo).rawAnnots;\n        } else {\n          ideo.rawAnnots = JSON.parse(text);\n        }\n        ideo.afterRawAnnots();\n      }\n    });\n}\n\n/**\n * Fills out annotations data structure such that its top-level list of arrays\n * matches that of this ideogram's chromosomes list in order and number\n * Fixes https://github.com/eweitz/ideogram/issues/66\n */\nfunction fillAnnots(annots) {\n  var filledAnnots, chrs, chrArray, i, chr, annot, chrIndex;\n\n  filledAnnots = [];\n  chrs = [];\n  chrArray = this.chromosomesArray;\n\n  for (i = 0; i < chrArray.length; i++) {\n    chr = chrArray[i].name;\n    chrs.push(chr);\n    filledAnnots.push({chr: chr, annots: []});\n  }\n\n  for (i = 0; i < annots.length; i++) {\n    annot = annots[i];\n    chrIndex = chrs.indexOf(annot.chr);\n    if (chrIndex !== -1) {\n      filledAnnots[chrIndex] = annot;\n    }\n  }\n\n  return filledAnnots;\n}\n\nexport {\n  onLoadAnnots, onDrawAnnots, processAnnotData, restoreDefaultTracks,\n  updateDisplayedTracks, initAnnotSettings, fetchAnnots, drawAnnots,\n  getHistogramBars, drawHeatmaps, deserializeAnnotsForHeatmap, fillAnnots,\n  drawProcessedAnnots, drawSynteny, startHideAnnotTooltipTimeout,\n  showAnnotTooltip, onWillShowAnnotTooltip, setOriginalTrackIndexes,\n  afterRawAnnots, onClickAnnot\n};\n","import {d3, slug} from '../lib';\n\n/**\n *  Returns NCBI Taxonomy identifier (taxid) for organism name\n */\nfunction getTaxidFromEutils(orgName, ideo) {\n  var taxonomySearch, taxid;\n\n  taxonomySearch = ideo.esearch + '&db=taxonomy&term=' + orgName;\n\n  return d3.json(taxonomySearch).then(function(data) {\n    taxid = data.esearchresult.idlist[0];\n    return [orgName, taxid];\n  });\n}\n\n/**\n * Returns organism common name given an NCBI Taxonomy ID\n *\n * @param taxid NCBI Taxonomy ID\n * @param callback Function to call upon completing ESearch request\n */\nfunction getOrganismFromEutils(taxid, callback) {\n  var organism, taxonomySearch,\n    ideo = this;\n\n  taxid = ideo.config.organism;\n\n  taxonomySearch = ideo.esummary + '&db=taxonomy&id=' + taxid;\n\n  d3.json(taxonomySearch).then(function(data) {\n    organism = data.result[String(taxid)].commonname;\n    ideo.config.organism = organism;\n    return callback(organism);\n  });\n}\n\nfunction setTaxidData(taxid, ideo) {\n\n  var dataDir, urlOrg, taxids;\n\n  if (ideo.assemblyIsAccession()) {\n    return new Promise(function(resolve) {\n      ideo.coordinateSystem = 'bp';\n      ideo.getAssemblyAndChromosomesFromEutils(taxid, resolve);\n    });\n  }\n\n  dataDir = ideo.config.dataDir;\n  urlOrg = slug(ideo.organisms[taxid].scientificName);\n\n  taxids = [taxid];\n\n  var fullyBandedTaxids = ['9606', '10090', '10116'];\n  if (fullyBandedTaxids.includes(taxid) && !ideo.config.showFullyBanded) {\n    urlOrg += '-no-bands';\n  }\n  var chromosomesUrl = dataDir + urlOrg + '.json';\n\n  var promise2 = new Promise(function(resolve, reject) {\n    fetch(chromosomesUrl).then(function(response) {\n      if (response.ok === false) {\n        reject(Error('Fetch failed for ' + chromosomesUrl));\n      } else {\n        return response.json().then(function(json) {\n          resolve(json.chrBands);\n        });\n      }\n    });\n  });\n\n  return promise2\n    .then(function(chrBands) {\n      // Check if chromosome data exists locally.\n      // This is used for pre-processed centromere data,\n      // which is not accessible via EUtils.  See get_chromosomes.py.\n\n      var asmAndChrTaxidsArray = [''],\n        chromosomes = [],\n        seenChrs = {},\n        chr, maxLength, splitBand, length;\n\n      ideo.bandData[taxid] = chrBands;\n\n      for (var i = 0; i < chrBands.length; i++) {\n        splitBand = chrBands[i].split(' ');\n        chr = splitBand[0];\n        length = splitBand.slice(-1)[0];\n        if (chr in seenChrs) {\n          continue;\n        } else {\n          chromosomes.push({name: chr, type: 'nuclear', length: length});\n          seenChrs[chr] = 1;\n        }\n      }\n      chromosomes = chromosomes.sort(Ideogram.sortChromosomes);\n      maxLength = {bp: 0, iscn: 0};\n      chromosomes.forEach(chr => {\n        if (chr.length > maxLength.bp) maxLength.bp = chr.length;\n      });\n      ideo.maxLength[taxid] = maxLength;\n      asmAndChrTaxidsArray.push(chromosomes);\n      asmAndChrTaxidsArray.push(taxids);\n      return asmAndChrTaxidsArray;\n    },\n    function() {\n      // If request in `then` errs (404), fetch data from EUtils\n      return new Promise(function(resolve) {\n        ideo.coordinateSystem = 'bp';\n        ideo.getAssemblyAndChromosomesFromEutils(taxid, resolve);\n      });\n    });\n}\n\nfunction setAssemblyAndChromosomes(taxid, resolve, ideo) {\n  var assembly, chrs, originalChrs, orgName, filteredChrs,\n    config = ideo.config;\n\n  setTaxidData(taxid, ideo)\n    .then(function(asmChrTaxidsArray) {\n      assembly = asmChrTaxidsArray[0];\n      chrs = asmChrTaxidsArray[1];\n\n      if ('chromosomes' in config === false || config.chromosomes === null) {\n        ideo.config.chromosomes = {};\n        ideo.config.chromosomes[taxid] = chrs;\n      } else {\n        if (config.multiorganism) {\n          if (taxid in config.chromosomes) {\n            // Encountered when either organism has centromere data\n            originalChrs = config.chromosomes[taxid];\n          } else {\n            // Encountered when neither organism has centromere data\n            orgName = slug(ideo.getScientificName(taxid));\n            ideo.config.chromosomes[taxid] =\n              config.chromosomes[orgName].slice();\n            originalChrs = ideo.config.chromosomes[taxid];\n            // delete ideo.config.chromosomes[orgName];\n          }\n        } else {\n          originalChrs = config.chromosomes;\n        }\n\n        filteredChrs = chrs.filter(d => originalChrs.includes(d.name));\n        ideo.config.chromosomes[taxid] = filteredChrs;\n      }\n      ideo.chromosomes[taxid] = ideo.config.chromosomes[taxid].slice();\n      ideo.organisms[taxid].assemblies = {\n        default: assembly\n      };\n      resolve();\n    });\n}\n\n/**\n * Determine if organism is natively supported, using its name.\n */\nfunction isOrganismSupported(org, ideo) {\n  var taxid, ideoOrg;\n\n  for (taxid in ideo.organisms) {\n    ideoOrg = ideo.organisms[taxid];\n    if (\n      taxid === slug(org) ||\n      slug(ideoOrg.commonName) === slug(org) ||\n      slug(ideoOrg.scientificName) === slug(org)\n    ) {\n      return true;\n    }\n  }\n\n  return false;\n}\n\n/**\n * Augment \"organisms\" metadata with for any requested organism that is\n * not natively supported (i.e., not in organism-metadata.js).\n*/\nfunction populateNonNativeOrg(orgs, ideo) {\n  var org, promise, i,\n    getTaxidFromEutilsPromises = [],\n    augmentedOrganismMetadata = {};\n\n  for (i = 0; i < orgs.length; i++) {\n    org = orgs[i];\n    if (isOrganismSupported(org, ideo) === false) {\n      promise = getTaxidFromEutils(org, ideo)\n        .then(function(orgNameAndTaxid) {\n\n          var taxid = orgNameAndTaxid[1],\n            orgName = orgNameAndTaxid[0],\n            name, scientificName;\n\n          name = orgName.replace('-', ' ');\n          scientificName = name[0].toUpperCase() + name.slice(1);\n\n          augmentedOrganismMetadata[taxid] = {\n            scientificName: scientificName,\n            commonName: '',\n            assemblies: {default: ''}\n          };\n\n          Object.assign(ideo.organisms, augmentedOrganismMetadata);\n        });\n    } else {\n      promise = new Promise(function(resolve) {\n        var taxid = ideo.getTaxid(org);\n        augmentedOrganismMetadata[taxid] = ideo.organisms[taxid];\n        resolve();\n      });\n    }\n    getTaxidFromEutilsPromises.push(promise);\n  }\n\n  return Promise.all(getTaxidFromEutilsPromises).then(function() {\n    return augmentedOrganismMetadata;\n  });\n}\n\nfunction prepareTmpChrsAndTaxids(ideo) {\n  var orgs, taxids, tmpChrs, org, taxid, chrsOrgSlugs,\n    config = ideo.config;\n\n  taxids = [];\n  tmpChrs = {};\n  orgs = (config.multiorganism) ? config.organism : [config.organism];\n\n  return populateNonNativeOrg(orgs, ideo).then(function(orgMetadata) {\n    var orgFields = orgMetadata[taxid];\n\n    for (taxid in orgMetadata) {\n      orgFields = orgMetadata[taxid];\n      taxids.push(taxid);\n      if (config.multiorganism) {\n        if (typeof config.chromosomes !== 'undefined') {\n          chrsOrgSlugs = Object.keys(config.chromosomes).map(org => slug(org));\n          // Adjusts 'chromosomes' configuration parameter to make object\n          // keys use taxid instead of common organism name\n          if (chrsOrgSlugs.includes(slug(orgFields.scientificName))) {\n            org = orgFields.scientificName;\n          } else if (chrsOrgSlugs.includes(slug(orgFields.commonName))) {\n            org = orgFields.commonName;\n          }\n          if (slug(org) in config.chromosomes) {\n            tmpChrs[taxid] = config.chromosomes[slug(org)];\n          } else {\n            tmpChrs[taxid] = config.chromosomes[org.toLowerCase()];\n          }\n        } else {\n          tmpChrs = null;\n        }\n      }\n    }\n    return [tmpChrs, taxids];\n  });\n}\n\n/**\n * Sort taxids by the \"organism\" configuration option\n *\n * TODO: Handle taxid being passed as organism\n */\nfunction sortTaxidsByOriginalOrganismOption(ideo) {\n  var configOrganisms, sortedTaxids, i;\n  configOrganisms = ideo.config.organism;\n  sortedTaxids = [];\n  if (Array.isArray(configOrganisms)) {\n    // Handling multi-organism ideogram\n    for (i = 0; i < configOrganisms.length; i++) {\n      sortedTaxids.push(ideo.getTaxid(configOrganisms[i]));\n    }\n  } else {\n    // Handling single-organism ideogram\n    sortedTaxids.push(ideo.getTaxid(configOrganisms));\n  }\n  return sortedTaxids;\n}\n\nfunction getTaxidsForOrganismsInConfig(callback, ideo) {\n\n  prepareTmpChrsAndTaxids(ideo).then(function([tmpChrs, taxids]) {\n    var i, taxid, promise, assemblies, asmAccs,\n      config = ideo.config,\n      asmAndChrPromises = [];\n\n    for (i = 0; i < taxids.length; i++) {\n      taxid = taxids[i];\n      assemblies = ideo.organisms[taxid].assemblies;\n      asmAccs = Object.values(assemblies);\n      if (\n        assemblies.default === '' ||\n        ideo.assemblyIsAccession() && !asmAccs.includes(config.assembly)\n      ) {\n        promise = new Promise(function(resolve) {\n          setAssemblyAndChromosomes(taxid, resolve, ideo);\n        });\n      } else {\n        ideo.config.taxids = taxids;\n        if (ideo.config.multiorganism) {\n          ideo.config.chromosomes = tmpChrs;\n        }\n        promise = new Promise(function(resolve) {\n          resolve();\n        });\n      }\n\n      asmAndChrPromises.push(promise);\n    }\n\n    Promise.all(asmAndChrPromises).then(function() {\n      taxids = sortTaxidsByOriginalOrganismOption(ideo);\n      ideo.config.taxids = taxids;\n      return callback(taxids);\n    });\n  });\n}\n\nfunction getIsMultiorganism(taxidInit, ideo) {\n  return (\n    ('organism' in ideo.config && ideo.config.organism instanceof Array) ||\n    (taxidInit && ideo.config.taxid instanceof Array)\n  );\n}\n\n/**\n * Configure Ideogram taxids when 'organism' is not in ideo.config\n */\nfunction getTaxidsForOrganismsNotInConfig(taxidInit, callback, ideo) {\n  var taxids;\n\n  if (ideo.config.multiorganism) {\n    if (taxidInit) {\n      taxids = ideo.config.taxid;\n    }\n  } else {\n    if (taxidInit) {\n      taxids = [ideo.config.taxid];\n    }\n    ideo.config.taxids = taxids;\n  }\n  callback(taxids);\n}\n\n/**\n * Returns an array of taxids for the current ideogram\n * Also sets configuration parameters related to taxid(s), whether ideogram is\n * multiorganism, and adjusts chromosomes parameters as needed\n **/\nfunction getTaxids(callback) {\n  var taxidInit,\n    ideo = this;\n\n  taxidInit = 'taxid' in ideo.config;\n\n  ideo.config.multiorganism = getIsMultiorganism(taxidInit, ideo);\n\n  if (ideo.config.multiorganism) ideo.coordinateSystem = 'bp';\n\n  if ('organism' in ideo.config) {\n    getTaxidsForOrganismsInConfig(callback, ideo);\n  } else {\n    getTaxidsForOrganismsNotInConfig(taxidInit, callback, ideo);\n  }\n}\n\nexport {\n  getTaxids, getOrganismFromEutils\n};\n","import {d3} from '../lib';\nimport {\n  esearch, esummary, elink, getAssemblySearchUrl\n} from './eutils-config.js';\nimport {\n  getTaxids, getOrganismFromEutils\n} from './organisms.js';\n\n/**\n * Get a URL to ESearch the NCBI Nucleotide DB for an Assembly UID\n */\nfunction getESearchUrlForChromosomes(asmUid, ideo) {\n  var qs;\n\n  // Get a list of IDs for the chromosomes in this genome.\n  //\n  // Query chromosomes sequences in Nucleotide DB (nuccore) via\n  // Assembly DB E-Utils link.\n  qs = ('&db=nuccore&dbfrom=assembly&linkname=assembly_nuccore&' +\n    'cmd=neighbor_history&from_uid=' + asmUid);\n\n  return d3.json(ideo.elink + qs)\n    .then(function(data) {\n      var webenv = data.linksets[0].webenv;\n      qs =\n        '&db=nuccore' +\n        '&term=%231+AND+%28' +\n          'sequence_from_chromosome[Properties]+OR+' +\n          'sequence_from_plastid[Properties]+OR+' +\n          'sequence_from_mitochondrion[Properties]%29' +\n        '&WebEnv=' + webenv + '&usehistory=y&retmax=1000';\n      return ideo.esearch + qs;\n    });\n}\n\n/**\n * Request basic data on a list of chromosome IDs from ESearch\n */\nfunction fetchNucleotideSummary(data, ideo) {\n  var ids, ntSummary;\n  ids = data.esearchresult.idlist.join(',');\n  ntSummary = ideo.esummary + '&db=nucleotide&id=' + ids;\n  return d3.json(ntSummary);\n}\n\n/**\n * Get name and type for mitochondrial chromosome\n *\n * See example of \"MT\" in yeast:\n * https://eweitz.github.io/ideogram/eukaryotes?org=saccharomyces-cerevisiae\n */\nfunction parseMitochondrion(result, ideo) {\n  var type, cnIndex, chrName;\n\n  if (ideo.config.showNonNuclearChromosomes) {\n    type = result.genome;\n    cnIndex = result.subtype.split('|').indexOf('plasmid');\n    if (cnIndex === -1) {\n      chrName = 'MT';\n    } else {\n      // Seen in e.g. rice genome IRGSP-1.0 (GCF_001433935.1),\n      // From https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?retmode=json&db=nucleotide&id=996703432,996703431,996703430,996703429,996703428,996703427,996703426,996703425,996703424,996703423,996703422,996703421,194033210,11466763,7524755\n      // genome: 'mitochondrion',\n      // subtype: 'cell_line|plasmid',\n      // subname: 'A-58 CMS|B1',\n      chrName = result.subname.split('|')[cnIndex];\n    }\n  } else {\n    return [null, null];\n  }\n\n  return [chrName, type];\n}\n\n/**\n * Get name and type for chloroplastic chromosome.\n *\n * Plants have chloroplasts.  See e.g. green algae:\n * https://eweitz.github.io/ideogram/eukaryotes?org=micromonas-commoda\n */\nfunction parseChloroplastOrPlastid(ideo) {\n  // Plastid encountered with rice genome IRGSP-1.0 (GCF_001433935.1)\n  if (ideo.config.showNonNuclearChromosomes) {\n    return ['CP', 'chloroplast'];\n  }\n  return [null, null];\n}\n\n/**\n * Get name and type for apicoplast chromosome\n *\n * Plasmodium falciparum (malaria parasite) has such a chromosome, see e.g.:\n * https://eweitz.github.io/ideogram/eukaryotes?org=plasmodium-falciparum\n */\nfunction parseApicoplast(ideo) {\n  if (ideo.config.showNonNuclearChromosomes) {\n    return ['AP', 'apicoplast'];\n  }\n  return [null, null];\n}\n\n/**\n * Get name and type for nuclear chromosome\n *\n * These are typical chromosomes, like chromosome 1.\n */\nfunction parseNuclear(result) {\n  var type, cnIndex, chrName;\n\n  type = 'nuclear';\n  cnIndex = result.subtype.split('|').indexOf('chromosome');\n  chrName = result.subname.split('|')[cnIndex];\n\n  if (typeof chrName !== 'undefined' && chrName.substr(0, 3) === 'chr') {\n    // Convert \"chr12\" to \"12\", e.g. for banana (GCF_000313855.2)\n    chrName = chrName.substr(3);\n  }\n\n  return [chrName, type];\n}\n\n/**\n * Get name and type of any chromosome object from NCBI Nucleotide ESummary\n */\nfunction getChrNameAndType(result, ideo) {\n  var genome = result.genome;\n  if (genome === 'mitochondrion') {\n    return parseMitochondrion(result, ideo);\n  } else if (genome === 'chloroplast' || genome === 'plastid') {\n    return parseChloroplastOrPlastid(ideo);\n  } else if (genome === 'apicoplast') {\n    return parseApicoplast(ideo);\n  } else {\n    return parseNuclear(result);\n  }\n}\n\nfunction parseChromosome(result, ideo) {\n  var chrName, type, chromosome;\n\n  [chrName, type] = getChrNameAndType(result, ideo);\n\n  chromosome = {\n    name: chrName,\n    length: result.slen,\n    type: type\n  };\n\n  return chromosome;\n}\n\nfunction parseChromosomes(results, taxid, ideo) {\n  var x, chromosome, seenChrId, maxLength,\n    seenChrs = {},\n    chromosomes = [];\n\n  for (x in results) {\n    // omit list of result uids\n    if (x === 'uids') continue;\n\n    chromosome = parseChromosome(results[x], ideo);\n    seenChrId = chromosome.name + '_' + chromosome.length;\n    if (chromosome.type !== null && seenChrId in seenChrs === false) {\n      // seenChrs accounts for duplicate chromosomes seen with\n      // pig (Sus scrofa), likely GenBank and RefSeq copies.\n      chromosomes.push(chromosome);\n    }\n\n    seenChrs[seenChrId] = 1;\n  }\n\n  chromosomes = chromosomes.sort(Ideogram.sortChromosomes);\n\n  maxLength = {bp: 0, iscn: 0};\n  chromosomes.forEach(chr => {\n    if (chr.length > maxLength.bp) maxLength.bp = chr.length;\n  });\n  if (maxLength.bp > ideo.maxLength.bp) ideo.maxLength.bp = maxLength.bp;\n  ideo.maxLength[taxid] = maxLength;\n  ideo.coordinateSystem = 'bp';\n\n  return chromosomes;\n}\n\n/**\n * Request ESummary data from an ESearch on a genome assembly\n */\nfunction fetchAssemblySummary(data, ideo) {\n  var asmUid, asmSummaryUrl;\n\n  // NCBI Assembly database's internal identifier (uid) for this assembly\n  asmUid = data.esearchresult.idlist[0];\n  asmSummaryUrl = ideo.esummary + '&db=assembly&id=' + asmUid;\n\n  return d3.json(asmSummaryUrl);\n}\n\n/**\n * Returns assembly accession, as well as names and lengths of chromosomes for\n * an organism's best-known genome assembly, or for a specified assembly.\n *\n * Gets data from NCBI EUtils web API.\n *\n * @param callback Function to call upon completion of this async method\n */\nfunction getAssemblyAndChromosomesFromEutils(taxid, callback) {\n  var assemblyAccession,\n    ideo = this;\n\n  // Search for assembly, then\n  // get summary of that assembly, then\n  // get search URL for chromosomes in that assembly, then\n  // get search results containing chromosome IDs, then\n  // get summaries of each of those chromosome IDs, then\n  // format the chromosome summaries and pass them into callback function.\n  var asmSearchUrl = getAssemblySearchUrl(taxid, ideo);\n  d3.json(asmSearchUrl)\n    .then(function(data) {return fetchAssemblySummary(data, ideo);})\n    .then(function(data) {\n      var asmUid = data.result.uids[0];\n      assemblyAccession = data.result[asmUid];\n      return getESearchUrlForChromosomes(asmUid, ideo);\n    }).then(function(esearchUrl) {return d3.json(esearchUrl);})\n    .then(function(data) {return fetchNucleotideSummary(data, ideo);})\n    .then(function(data) {\n      var chromosomes = parseChromosomes(data.result, taxid, ideo);\n      return callback([assemblyAccession, chromosomes]);\n    }, function(rejectedReason) {\n      console.warn(rejectedReason);\n    });\n}\n\nexport {\n  esearch, esummary, elink, getOrganismFromEutils,\n  getTaxids, getAssemblyAndChromosomesFromEutils\n};\n","// The E-Utilies In Depth: Parameters, Syntax and More:\n// https://www.ncbi.nlm.nih.gov/books/NBK25499/\n\nvar apiKey = '&api_key=7e33ac6a08a6955ec3b83d214d22b21a2808';\n\nvar eutils = 'https://eutils.ncbi.nlm.nih.gov/entrez/eutils/';\nvar esearch = eutils + 'esearch.fcgi?retmode=json' + apiKey;\nvar esummary = eutils + 'esummary.fcgi?retmode=json' + apiKey;\nvar elink = eutils + 'elink.fcgi?retmode=json' + apiKey;\n\nfunction getAssemblySearchUrl(taxid, ideo) {\n  var termStem, asmSearchUrl;\n\n  if (ideo.assemblyIsAccession()) {\n    termStem = ideo.config.assembly + '%22[Assembly%20Accession]';\n  } else {\n    termStem = (\n      taxid + '%22[taxid]' +\n      'AND%20(%22latest%20refseq%22[filter])%20'\n    );\n  }\n\n  asmSearchUrl =\n    ideo.esearch +\n    '&db=assembly' +\n    '&term=%22' + termStem +\n    'AND%20(%22chromosome%20level%22[filter]%20' +\n    'OR%20%22complete%20genome%22[filter])';\n\n  return asmSearchUrl;\n}\n\nexport {esearch, esummary, elink, getAssemblySearchUrl};\n","/**\n * @fileoverview Methods to show (or hide) cytogenetic banding data\n */\n\nimport {d3} from '../lib';\n\nfunction hideUnshownBandLabels() {\n  var ideo = this;\n  var bandsToShow = ideo.bandsToShow.join(',');\n\n  // d3.selectAll resolves to querySelectorAll (QSA).\n  // QSA takes a surprisingly long time to complete,\n  // and scales with the number of selectors.\n  // Most bands are hidden, so we can optimize by\n  // Hiding all bands, then QSA'ing and displaying the\n  // relatively few bands that are shown.\n  d3.selectAll(ideo.selector + ' .bandLabel, .bandLabelStalk')\n    .style('display', 'none');\n  d3.selectAll(bandsToShow).style('display', '');\n}\n\nfunction getPrevRight(prevLabelXRight, prevHiddenBoxIndex, i,\n  textOffsets, chrModel) {\n  var prevTextBoxLeft, prevTextBoxWidth;\n\n  if (prevHiddenBoxIndex !== i) {\n    // This getBoundingClientRect() forces Chrome's\n    // 'Recalculate Style' and 'Layout', which takes 30-40 ms on Chrome.\n    // TODO: This forced synchronous layout would be nice to eliminate.\n    // prevTextBox = texts[i].getBoundingClientRect();\n    // prevLabelXRight = prevTextBox.left + prevTextBox.width;\n\n    // TODO: Account for number of characters in prevTextBoxWidth,\n    // maybe also zoom.\n    prevTextBoxLeft = textOffsets[chrModel.id][i];\n    prevTextBoxWidth = 36;\n\n    prevLabelXRight = prevTextBoxLeft + prevTextBoxWidth;\n  }\n\n  return prevLabelXRight;\n}\n\nfunction updateShown(indexesToShow, overlapRight, left, pad, prevRight, i,\n  isBefore) {\n  var hiddenIndex, doSkip,\n    thisRight = isBefore ? overlapRight : prevRight;\n\n  if (left < pad + thisRight) {\n    overlapRight = prevRight;\n    hiddenIndex = i;\n    doSkip = isBefore;\n  } else {\n    indexesToShow.push(i);\n  }\n\n  return [indexesToShow, overlapRight, hiddenIndex, doSkip];\n}\n\nfunction getIndexesToShow(offsets, chrModel) {\n  var i, hiddenIndex, left, prevRight, doSkip,\n    indexesToShow = [],\n    textsLength = offsets[chrModel.id].length,\n    overlapRight = 0, // Right X coordinate of overlapping label\n    pad = 5; // text padding\n\n  for (i = 0; i < textsLength; i++) {\n    // Ensures band labels don't overlap\n    left = offsets[chrModel.id][i];\n\n    [indexesToShow, overlapRight, hiddenIndex, doSkip] =\n      updateShown(indexesToShow, overlapRight, left, pad, prevRight, i, true);\n    if (doSkip) continue;\n\n    prevRight = getPrevRight(prevRight, hiddenIndex, i, offsets, chrModel);\n\n    [indexesToShow, overlapRight, hiddenIndex, doSkip] =\n      updateShown(indexesToShow, overlapRight, left, pad, prevRight, i, false);\n  }\n\n  return indexesToShow;\n}\n\n/**\n * Sets band labels to display on each chromosome, avoiding label overlap\n */\nfunction setBandsToShow(chrs, textOffsets) {\n  var index, i, j, indexesToShow, chrModel, selectorsToShow, ithLength,\n    ideo = this;\n\n  ideo.bandsToShow = [];\n\n  for (i = 0; i < chrs.length; i++) {\n\n    chrModel = chrs[i];\n\n    indexesToShow = getIndexesToShow(textOffsets, chrModel);\n\n    selectorsToShow = [];\n    ithLength = indexesToShow.length;\n\n    for (j = 0; j < ithLength; j++) {\n      index = indexesToShow[j];\n      selectorsToShow.push('#' + chrModel.id + ' .bsbsl-' + index);\n    }\n\n    ideo.bandsToShow = ideo.bandsToShow.concat(selectorsToShow);\n  }\n}\n\nexport {hideUnshownBandLabels, setBandsToShow};\n","/**\n * @fileoverview Methods to draw cytogenetic bands and their labels\n *\n */\n\nimport {d3} from '../lib';\nimport {hideUnshownBandLabels, setBandsToShow} from './show';\nimport {staticColors, staticGradients} from './styles';\nimport {configuredCss} from './../init/configure';\n\n/**\n * Draws text of cytoband label\n */\nfunction drawBandLabelText(chr, bandsToLabel, chrModel, textOffsets) {\n  var ideo = this,\n    layout = ideo._layout,\n    chrIndex = chrModel.chrIndex;\n\n  chr.selectAll('text')\n    .data(bandsToLabel)\n    .enter()\n    .append('g')\n    .attr('class', function(d, i) {\n      return 'bandLabel bsbsl-' + i;\n    })\n    .attr('transform', function(d) {\n      var transform = layout.getChromosomeBandLabelTranslate(d, chrIndex);\n\n      if (ideo.config.orientation === 'horizontal') {\n        textOffsets[chrModel.id].push(transform.x + 13);\n      } else {\n        textOffsets[chrModel.id].push(transform.y + 6);\n      }\n\n      return transform.translate;\n    })\n    .append('text')\n    .attr('text-anchor', layout.getChromosomeBandLabelAnchor(chrIndex))\n    .text(function(d) {return d.name;});\n\n  return textOffsets;\n}\n\n/**\n * Draws line between cytoband and its text label\n */\nfunction drawBandLabelStalk(chr, bandsToLabel, chrModel, textOffsets) {\n  var ideo = this;\n\n  chr.selectAll('line.bandLabelStalk')\n    .data(bandsToLabel)\n    .enter()\n    .append('g')\n    .attr('class', function(d, i) {\n      return 'bandLabelStalk bsbsl-' + i;\n    })\n    .attr('transform', function(d) {\n      var x, y;\n\n      x = ideo.round(d.px.start + d.px.width / 2);\n      y = -10;\n\n      textOffsets[chrModel.id].push(x + 13);\n\n      return 'translate(' + x + ',' + y + ')';\n    })\n    .append('line')\n    .attr('x1', 0)\n    .attr('y1', ideo._layout.getChromosomeBandTickY1(chrModel.chrIndex))\n    .attr('x2', 0)\n    .attr('y2', ideo._layout.getChromosomeBandTickY2(chrModel.chrIndex));\n}\n\nfunction getChrModels(chromosomes) {\n  var taxid, chr,\n    chrModels = [];\n\n  for (taxid in chromosomes) {\n    for (chr in chromosomes[taxid]) {\n      chrModels.push(chromosomes[taxid][chr]);\n    }\n  }\n\n  return chrModels;\n}\n\n/**\n * Draws text and stalks for cytogenetic band labels.\n *\n * Band labels are text like \"p11.11\".\n * Stalks are small lines that visually connect labels to their bands.\n */\nfunction drawBandLabels(chromosomes) {\n  var i, chr, chrModel, chrModels, bandsToLabel,\n    ideo = this,\n    textOffsets = {};\n\n  chrModels = getChrModels(chromosomes);\n\n  for (i = 0; i < chrModels.length; i++) {\n    chrModel = chrModels[i];\n    chr = d3.select(ideo.selector + ' #' + chrModel.id);\n    textOffsets[chrModel.id] = [];\n\n    // Don't show \"pter\" label for telocentric chromosomes, e.g. mouse\n    bandsToLabel = chrModel.bands.filter(d => d.name !== 'pter');\n\n    textOffsets =\n      ideo.drawBandLabelText(chr, bandsToLabel, chrModel, textOffsets);\n\n    ideo.drawBandLabelStalk(chr, bandsToLabel, chrModel, textOffsets);\n  }\n\n  ideo.setBandsToShow(chrModels, textOffsets);\n}\n\nfunction getStainAndColors(i, colors) {\n  var stain, color1, color2, color3;\n\n  stain = colors[i][0];\n  color1 = colors[i][1];\n  color2 = colors[i][2];\n  color3 = colors[i][3];\n\n  return [stain, color1, color2, color3];\n}\n\nfunction getGradients(colors) {\n  var i, stain, color1, color2, color3,\n    gradients = '';\n\n  for (i = 0; i < colors.length; i++) {\n    [stain, color1, color2, color3] = getStainAndColors(i, colors);\n    gradients +=\n      '<linearGradient id=\"' + stain + '\" x1=\"0%\" y1=\"0%\" x2=\"0%\" y2=\"100%\">';\n    if (stain === 'gneg') {\n      gradients +=\n        '<stop offset=\"70%\" stop-color=\"' + color2 + '\" />' +\n        '<stop offset=\"95%\" stop-color=\"' + color3 + '\" />' +\n        '<stop offset=\"100%\" stop-color=\"' + color1 + '\" />';\n    } else {\n      gradients +=\n        '<stop offset=\"5%\" stop-color=\"' + color1 + '\" />' +\n        '<stop offset=\"15%\" stop-color=\"' + color2 + '\" />' +\n        '<stop offset=\"60%\" stop-color=\"' + color3 + '\" />';\n    }\n    gradients +=\n      '</linearGradient>';\n  }\n\n  return gradients;\n}\n\n/**\n * Returns SVG gradients that give chromosomes a polished look\n */\nfunction getBandColorGradients() {\n  var css,\n    gradients = '';\n\n  gradients = getGradients(staticColors);\n\n  css = `<style>${configuredCss}</style>`;\n\n  gradients += staticGradients;\n  gradients = '<defs>' + gradients + '</defs>';\n  gradients = css + gradients;\n\n  return gradients;\n}\n\nexport {\n  drawBandLabels, getBandColorGradients, hideUnshownBandLabels, setBandsToShow,\n  drawBandLabelText, drawBandLabelStalk\n};\n","\nfunction getDelimiterTsvLinesAndInit(source, content) {\n  var delimiter, tsvLines, init;\n\n  if (typeof chrBands === 'undefined' && source !== 'native') {\n    delimiter = /\\t/;\n    tsvLines = content.split(/\\r\\n|\\n/);\n    init = 1;\n  } else {\n    delimiter = / /;\n    tsvLines = content;\n    init = 0;\n  }\n\n  return [delimiter, tsvLines, init];\n}\n\nfunction updateChromosomes(chromosomes) {\n  var tmp, i;\n\n  if (chromosomes instanceof Array && typeof chromosomes[0] === 'object') {\n    tmp = [];\n    for (i = 0; i < chromosomes.length; i++) {\n      tmp.push(chromosomes[i].name);\n    }\n    chromosomes = tmp;\n  }\n  return chromosomes;\n}\n\nfunction getLineObject(chr, columns, stain, taxid) {\n  return {\n    chr: chr,\n    bp: {\n      start: parseInt(columns[5], 10),\n      stop: parseInt(columns[6], 10)\n    },\n    iscn: {\n      start: parseInt(columns[3], 10),\n      stop: parseInt(columns[4], 10)\n    },\n    px: {\n      start: -1,\n      stop: -1,\n      width: -1\n    },\n    name: columns[1] + columns[2],\n    stain: stain,\n    taxid: taxid\n  };\n}\n\nfunction getStain(columns) {\n  var stain = columns[7];\n  // For e.g. acen and gvar, columns[8] (density) is undefined\n  if (columns[8]) stain += columns[8];\n  return stain;\n}\n\nfunction updateLines(lines, columns, taxid) {\n  var chr, stain, line;\n\n  chr = columns[0];\n  if (chr in lines === false) lines[chr] = [];\n\n  stain = getStain(columns);\n\n  line = getLineObject(chr, columns, stain, taxid);\n  lines[chr].push(line);\n\n  return lines;\n}\n\n/**\n * Reports if a cytogenetic band should be included in parse results\n *\n * TODO:\n * Normalize ideogram.chromosomes upstream.\n *\n * This function is complex because ideogram.chromosomes is (likely\n * unnecessarily) complex.  The \"ideogram.chromosomes\" object can\n * take many forms depending on the use case, and this results in\n * hard-to-reason-about functions like this.\n *\n * Normalizing ideogram.chromosomes to a common format somewhere upstream\n * would likely make this specific function and Ideogram in general much\n * more maintainable.\n */\nfunction shouldSkipBand(chrs, chr, taxid, ideo) {\n\n  var hasChrs, chrsAreList, chrNotInList, chrsAreObject,\n    innerChrsAreStrings, matchingChrObjs, chrNotInObject,\n    multiorganism = ideo.config.multiorganism;\n\n  hasChrs = typeof chrs !== 'undefined' && chrs !== null;\n  if (!hasChrs) return false;\n\n  chrsAreList = Array.isArray(chrs);\n  chrNotInList = chrsAreList && chrs.indexOf(chr) === -1;\n  chrsAreObject = typeof chrs === 'object';\n\n  if (chrsAreList && !chrsAreObject && chrNotInList) return true;\n\n  if (taxid in chrs === false && multiorganism) return false;\n\n  if (!multiorganism) {\n    // Encountered in single organism when showing subset of all chromosomes,\n    // e.g. only human X and Y as in https://eweitz.github.io/ideogram/homology-basic\n    matchingChrObjs = chrs.filter(thisChr => thisChr === chr);\n    chrNotInObject = matchingChrObjs.length === 0;\n  } else {\n    innerChrsAreStrings = typeof chrs[taxid][0] === 'string';\n    if (innerChrsAreStrings) {\n      chrNotInObject = chrs[taxid].includes(chr) === false;\n    } else {\n      matchingChrObjs = chrs[taxid].filter(thisChr => thisChr.name === chr);\n      chrNotInObject = matchingChrObjs.length === 0;\n    }\n  }\n  return chrNotInObject;\n\n}\n\n/**\n * Parses cytogenetic band data from a TSV file, or, if band data is\n * prefetched, from an array\n *\n * NCBI:\n * #chromosome arm band iscn_start iscn_stop bp_start bp_stop stain density\n * ftp://ftp.ncbi.nlm.nih.gov/pub/gdp/ideogram_9606_GCF_000001305.14_550_V1\n */\nfunction parseBands(taxid, chromosomes, ideo) {\n  var delimiter, tsvLines, columns, chr, i, init, source, content,\n    lines = {};\n\n  content = ideo.bandData[taxid];\n\n  if (Array.isArray(content)) source = 'native';\n\n  chromosomes = updateChromosomes(chromosomes);\n\n  // Destructure assignment fails oddly when transpiled.  2019-05-23\n  var result = getDelimiterTsvLinesAndInit(source, content);\n  delimiter = result[0];\n  tsvLines = result[1];\n  init = result[2];\n\n  for (i = init; i < tsvLines.length; i++) {\n    columns = tsvLines[i].split(delimiter);\n\n    chr = columns[0];\n    if (shouldSkipBand(chromosomes, chr, taxid, ideo)) {\n      // If specific chromosomes are configured, then skip processing all\n      // other fetched chromosomes.\n      continue;\n    }\n\n    lines = updateLines(lines, columns, taxid);\n  }\n\n  return lines;\n}\n\nexport {parseBands};\n","/**\n * @fileoverview Methods for processing chromosome length and banding data.\n *\n * Ideogram.js depicts chromosomes using data on their length, name, and\n * (if dealing with a very well-studied organism) cytogenetic banding data.\n * This file processes cytoband data that comes from biological research\n * institutions.\n *\n * For background on cytogenetic bands and how they are used in genomics, see:\n * https://ghr.nlm.nih.gov/primer/howgeneswork/genelocation\n *\n */\n\nimport {\n  drawBandLabels, getBandColorGradients, hideUnshownBandLabels, setBandsToShow,\n  drawBandLabelText, drawBandLabelStalk\n} from './draw';\nimport {parseBands} from './parse';\nimport {organismMetadata} from '../init/organism-metadata';\n\n/**\n * Gets bands array for given chromosomes, sets ideo.maxLength\n */\nfunction getBandsArray(chromosome, bandsByChr, taxid, ideo) {\n  var bands, chrLength,\n    bandsArray = [];\n\n  bands = bandsByChr[chromosome];\n  bandsArray.push(bands);\n\n  chrLength = {\n    iscn: bands[bands.length - 1].iscn.stop,\n    bp: bands[bands.length - 1].bp.stop\n  };\n\n  if (taxid in ideo.maxLength === false) {\n    ideo.maxLength[taxid] = {bp: 0, iscn: 0};\n  }\n\n  if (chrLength.iscn > ideo.maxLength[taxid].iscn) {\n    ideo.maxLength[taxid].iscn = chrLength.iscn;\n    if (chrLength.iscn > ideo.maxLength.iscn) {\n      ideo.maxLength.iscn = chrLength.iscn;\n    }\n  }\n\n  if (chrLength.bp > ideo.maxLength[taxid].bp) {\n    ideo.maxLength[taxid].bp = chrLength.bp;\n    if (chrLength.bp > ideo.maxLength.bp) {\n      ideo.maxLength.bp = chrLength.bp;\n    }\n  }\n\n  return bandsArray;\n}\n\n/**\n * Updates bandsArray, sets ideo.config.chromosomes and ideo.numChromosomes\n */\nfunction setChrsByTaxidsWithBands(taxid, chrs, bandsArray, ideo) {\n  var bandsByChr, chromosome, k, chrBandsArray;\n\n  bandsByChr = parseBands(taxid, chrs, ideo);\n\n  chrs = Object.keys(bandsByChr).sort(function(a, b) {\n    return a.localeCompare(b, 'en', {numeric: true});\n  });\n\n  if (\n    'chromosomes' in ideo.config === false ||\n    ideo.config.chromosomes === null\n  ) {\n    ideo.config.chromosomes = {};\n  }\n  if (chrs.length > 0) {\n    ideo.config.chromosomes[taxid] = chrs.slice();\n  }\n  ideo.numChromosomes += ideo.config.chromosomes[taxid].length;\n\n  for (k = 0; k < chrs.length; k++) {\n    chromosome = chrs[k];\n    chrBandsArray = getBandsArray(chromosome, bandsByChr, taxid, ideo);\n    bandsArray = bandsArray.concat(chrBandsArray);\n  }\n\n  return bandsArray;\n}\n\nfunction setChromosomesByTaxid(taxid, chrs, bandsArray, ideo) {\n  var chr, i;\n\n  if (\n    taxid in ideo.bandData ||\n    taxid in organismMetadata &&\n    ideo.assemblyIsAccession() === false\n  ) {\n    bandsArray = setChrsByTaxidsWithBands(taxid, chrs, bandsArray, ideo);\n  } else {\n    // If lacking band-level data\n    ideo.numChromosomes += chrs.length;\n\n    for (i = 0; i < chrs.length; i++) {\n      chr = chrs[i];\n      if (chr.length > ideo.maxLength.bp) ideo.maxLength.bp = chr.length;\n    }\n  }\n\n  return bandsArray;\n}\n\nfunction reportPerformance(t0, ideo) {\n  var t1 = new Date().getTime();\n  if (ideo.config.debug) {\n    console.log('Time in processBandData: ' + (t1 - t0) + ' ms');\n  }\n}\n\n/**\n * Completes default ideogram initialization by calling downstream functions\n * to process raw band data into full JSON objects, render chromosome and\n * cytoband figures and labels, apply initial graphical transformations,\n * hide overlapping band labels, and execute callbacks defined by client code\n */\nfunction processBandData(taxid) {\n  var bandsArray, chrs,\n    ideo = this,\n    config = ideo.config,\n    t0 = new Date().getTime();\n\n  bandsArray = [];\n\n  if ('chromosomes' in config) {\n    if (config.multiorganism) {\n      // Copy object\n      chrs = config.chromosomes;\n    } else if (taxid in config.chromosomes) {\n      // Copy array by value\n      chrs = config.chromosomes[taxid].slice();\n    } else {\n      // Copy array by value.  Needed for e.g. \"Homology, basic\"\n      chrs = config.chromosomes.slice();\n    }\n  }\n\n  bandsArray = setChromosomesByTaxid(taxid, chrs, bandsArray, ideo);\n\n  reportPerformance(t0, ideo);\n  return [taxid, bandsArray];\n}\n\nexport {\n  drawBandLabels, getBandColorGradients, processBandData,\n  setBandsToShow, hideUnshownBandLabels, drawBandLabelText, drawBandLabelStalk\n};\n","/**\n * @fileoverview Methods to create and handle a brush on a chromosome.\n *\n * Ideogram.js enables users to display a box around part of a chromosome\n * that represents a \"currently selected\" region.  The user can move this\n * box like a sliding window, e.g. by clicking and dragging the mouse.\n *\n * For background, see:\n * https://github.com/d3/d3-brush\n */\n\nimport {d3} from './lib';\n// See https://github.com/d3/d3/issues/2733\nimport {event as currentEvent} from 'd3-selection';\n\n/**\n * Custom event handler, fired upon dragging sliding window on chromosome\n */\nfunction onBrushMove() {\n  call(this.onBrushMoveCallback);\n}\n\nfunction setBrush(bpDomain, pxRange, xOffset, width, ideo) {\n  var xScale,\n    length = ideo.config.chrHeight;\n\n  xScale = d3.scaleLinear().domain(bpDomain).range(pxRange);\n\n  ideo.brush = d3.brushX()\n    .extent([[xOffset, 0], [length + xOffset, width]])\n    .on('brush', onBrushMove);\n\n  function onBrushMove() {\n    var extent = currentEvent.selection.map(xScale.invert),\n      from = Math.floor(extent[0]),\n      to = Math.ceil(extent[1]);\n\n    ideo.selectedRegion = {from: from, to: to, extent: (to - from)};\n\n    if (ideo.onBrushMove) {\n      ideo.onBrushMoveCallback();\n    }\n  }\n}\n\nfunction getBasePairDomainAndPixelRange(chrModel, xOffset) {\n  var band, i,\n    bpDomain = [1],\n    pxRange = [1],\n    lastBand = chrModel.bands.slice(-1)[0];\n\n  for (i = 0; i < chrModel.bands.length; i++) {\n    band = chrModel.bands[i];\n    bpDomain.push(band.bp.start);\n    pxRange.push(band.px.start + xOffset);\n  }\n\n  bpDomain.push(lastBand.bp.stop - 1);\n  pxRange.push(lastBand.px.stop + xOffset);\n\n  return [bpDomain, pxRange];\n}\n\n/**\n * Account for calls like createBrush('chr1:104325484-119977655')\n */\nfunction refineGenomicCoordinates(chr, from, to) {\n  var nameSplit, fromToSplit;\n\n  // Account for calls like createBrush('chr1:104325484-119977655')\n  nameSplit = chr.split(':');\n  fromToSplit = chr.split('-');\n  if (nameSplit.length > 1 && fromToSplit.length > 1) {\n    chr = nameSplit[0].replace('chr', '');\n    fromToSplit = nameSplit[1].split('-');\n    from = parseInt(fromToSplit[0]);\n    to = parseInt(fromToSplit[1] - 1);\n  }\n\n  return [chr, from, to];\n}\n\nfunction getChrModel(chr, ideo) {\n  var i, cm, chrModel;\n\n  for (i = 0; i < ideo.chromosomesArray.length; i++) {\n    cm = ideo.chromosomesArray[i];\n    if (cm.name === chr) {\n      chrModel = cm;\n      return chrModel;\n    }\n  }\n}\n\nfunction writeBrush(chrModel, from, to, xOffset, width, ideo) {\n  var x0, x1, yTranslate, yOffset;\n\n  x0 = ideo.convertBpToPx(chrModel, from) + xOffset;\n  x1 = ideo.convertBpToPx(chrModel, to) + xOffset;\n\n  yTranslate = ideo._layout.getChromosomeSetYTranslate(0);\n  yOffset = yTranslate + (ideo.config.chrWidth - width) / 2;\n\n  d3.select(ideo.selector).append('g')\n    .attr('class', 'brush')\n    .attr('transform', 'translate(0, ' + yOffset + ')')\n    .call(ideo.brush)\n    .call(ideo.brush.move, [x0, x1]);\n}\n\nfunction setSelectedRegion(from, to, ideo) {\n  // Genomics web UIs are 1-based, fully closed.\n  // I.e. If start = 20 bp and stop = 10 bp, then extent = 11 bp.\n  // Details:\n  // http://genome.ucsc.edu/blog/the-ucsc-genome-browser-coordinate-counting-systems/\n  // https://www.biostars.org/p/84686/\n  var extent = to - from + 1;\n  ideo.selectedRegion = {from: from, to: to, extent: extent};\n}\n\n/**\n * Creates a sliding window along a chromosome\n *\n * @param chr Chromosome name (e.g. 1) or range, e.g. chr1:104325484-119977655\n * @param from Genomic start coordinate in base pairs, e.g. 104325484\n * @param to Genomic end coordinate in base pairs, e.g. 119977655\n */\nfunction createBrush(chr, from, to) {\n  var chrModel, chrLengthBp, bpDomain, pxRange, lastBand,\n    ideo = this,\n    width = ideo.config.chrWidth + 6.5,\n    xOffset = ideo._layout.margin.left;\n\n  [chr, from, to] = refineGenomicCoordinates(chr, from, to);\n\n  chrModel = getChrModel(chr, ideo);\n\n  [bpDomain, pxRange] = getBasePairDomainAndPixelRange(chrModel, xOffset);\n\n  lastBand = chrModel.bands.slice(-1)[0];\n  chrLengthBp = lastBand.bp.stop;\n\n  if (typeof from === 'undefined') from = Math.floor(chrLengthBp / 10);\n  if (typeof to === 'undefined') to = Math.ceil(from * 2);\n\n  setBrush(bpDomain, pxRange, xOffset, width, ideo);\n\n  setSelectedRegion(from, to, ideo);\n  writeBrush(chrModel, from, to, xOffset, width, ideo);\n}\n\nexport {onBrushMove, createBrush};\n","/**\n * @fileoverview Allows a click event handler to be attached to the ideogram\n *\n * This works similar to the \"brush\" which allows a region to be selected.\n * The click handler does not allow a region, but a precise location.\n *\n */\n\nimport {d3} from './lib';\n// See https://github.com/d3/d3/issues/2733\nimport {event as currentEvent} from 'd3-selection';\n\n/**\n * Custom event handler, fired upon clicks on the chromosome (to change\n * position)\n */\nfunction onCursorMove() {\n  call(this.onCursorMoveCallback);\n}\n\nfunction setCursor(position, bpDomain, pxRange, xOffset, width, ideo) {\n  var xScale;\n\n  xScale = d3.scaleLinear().domain(bpDomain).range(pxRange);\n\n  if (!('rotatable' in ideo.config && ideo.config.rotatable === false)) {\n    console.warn('Using the cursor with rotate is not supported.');\n  }\n\n  var yTranslate = ideo._layout.getChromosomeSetYTranslate(0);\n  var yOffset = yTranslate + (ideo.config.chrWidth - width) / 2;\n\n  // TODO: check if newPosition is valid value (in range)\n\n  var cursorBrush = d3.select(ideo.selector).append('g')\n    .attr('class', 'brush')\n    .attr('transform', 'translate(0, ' + yOffset + ')')\n    .append('rect')\n    .attr('class', 'cursor')\n    .attr('x', xScale(position))\n    .attr('y', 0)\n    .attr('width', 1) // this could be a configuration param\n    .attr('height', 30); // MAGIC NUMBER! need help with this one\n\n  // call the callback for the first time (onLoad)\n  if (ideo.onCursorMove) {\n    ideo.onCursorMoveCallback(position);\n  }\n\n  if (!ideo.setCursorPosition) {\n    ideo.setCursorPosition = function(newPosition) {\n      // TODO: check if newPosition is valid value (in range)\n      cursorBrush.attr('x', xScale(newPosition));\n      if (ideo.onCursorMove) {\n        ideo.onCursorMoveCallback(newPosition);\n      }\n    };\n  }\n\n  d3.selectAll(ideo.selector + ' .chromosome').on('click', function() {\n    var extent = currentEvent;\n    var x = extent.clientX - (xOffset*2);\n    console.log(\"extent\", extent);\n    console.log(\"xOffset\", xOffset);\n    console.log(\"x\", x);\n    var newPosition = Math.floor(xScale.invert(x));\n\n    // move the cursor\n    cursorBrush.attr('x', x);\n\n    if (ideo.onCursorMove) {\n      ideo.onCursorMoveCallback(newPosition);\n    }\n  });\n}\n\nfunction getBasePairDomainAndPixelRange(chrModel, xOffset) {\n  var band, i,\n    bpDomain = [1],\n    pxRange = [1],\n    lastBand = chrModel.bands.slice(-1)[0];\n\n  for (i = 0; i < chrModel.bands.length; i++) {\n    band = chrModel.bands[i];\n    bpDomain.push(band.bp.start);\n    pxRange.push(band.px.start + xOffset);\n  }\n\n  bpDomain.push(lastBand.bp.stop - 1);\n  pxRange.push(lastBand.px.stop + xOffset);\n\n  return [bpDomain, pxRange];\n}\n\nfunction getChrModel(chr, ideo) {\n  var i, cm, chrModel;\n\n  for (i = 0; i < ideo.chromosomesArray.length; i++) {\n    cm = ideo.chromosomesArray[i];\n    if (cm.name === chr) {\n      chrModel = cm;\n      return chrModel;\n    }\n  }\n}\n\n/**\n * Creates a clickable cursor along a chromosome.\n *\n * @param position Genomic start coordinate in base pairs, e.g. 104325484\n */\nfunction createClickCursor(position) {\n  var chrModel, bpDomain,\n    pxRange,\n    ideo = this,\n    width = ideo.config.chrWidth + 6.5, // 6.5 magic number?\n    xOffset = ideo._layout.margin.left;\n\n  if (typeof position === 'undefined') {\n    return false;\n  }\n\n  chrModel = getChrModel(ideo.config.chromosome, ideo);\n  [bpDomain, pxRange] = getBasePairDomainAndPixelRange(chrModel, xOffset);\n\n  // call setCursor to complete the job.\n  setCursor(position, bpDomain, pxRange, xOffset, width, ideo);\n}\n\nexport {onCursorMove, createClickCursor};\n","/**\n * @fileoverview Instance methods for sex chromosomes (allosomes).\n *\n * This module provides methods for drawing karyotypically normal\n * male and female mammalian genomes.\n */\n\n/**\n * Appends SVG elements depicting sex chromosomes to the document.\n */\nfunction drawSexChromosomes(container, chrIndex) {\n  var bandsArray, taxid, chrs,\n    sexChromosomeIndexes, sciLength,\n    chromosome, bands, chrModel, sci, homologIndex;\n\n  bandsArray = this.bandsArray;\n  taxid = this.config.taxid;\n  chrs = this.config.chromosomes[taxid];\n\n  if (this.config.sex === 'male') {\n    sexChromosomeIndexes = [1, 0];\n  } else {\n    sexChromosomeIndexes = [0, 0];\n  }\n\n  sciLength = sexChromosomeIndexes.length;\n\n  for (homologIndex = 0; homologIndex < sciLength; homologIndex++) {\n    sci = sexChromosomeIndexes[homologIndex] + chrIndex;\n    chromosome = chrs[sci];\n    bands = bandsArray[taxid][sci];\n    chrModel = this.getChromosomeModel(bands, chromosome, taxid, sci);\n    this.appendHomolog(chrModel, chrIndex, homologIndex, container);\n  }\n}\n\n/**\n * Sets instance properties regarding sex chromosomes.\n * Currently only supported for mammals.\n * TODO: Support all sexually reproducing taxa\n *   XY sex-determination (mammals):\n *     - Male: XY <- heterogametic\n *     - Female: XX\n *   ZW sex-determination (birds):\n *     - Male: ZZ\n *     - Female: ZW <- heterogametic\n *   X0 sex-determination (some insects):\n *     - Male: X0, i.e. only X <- heterogametic?\n *     - Female: XX\n * TODO: Support sex chromosome aneuploidies in mammals\n *     - Turner syndrome: X0\n *     - Klinefelter syndome: XXY\n *  More types:\n *  https://en.wikipedia.org/wiki/Category:Sex_chromosome_aneuploidies\n */\nfunction setSexChromosomes(chrs) {\n  var chr, i,\n    ideo = this,\n    sexChrs = {X: 1, Y: 1};\n\n  if (this.config.ploidy !== 2 || !this.config.sex) return;\n\n  ideo.sexChromosomes.list = [];\n\n  for (i = 0; i < chrs.length; i++) {\n    chr = chrs[i];\n    if (ideo.config.sex === 'male' && chr in sexChrs) {\n      ideo.sexChromosomes.list.push(chr);\n      if (!ideo.sexChromosomes.index) {\n        ideo.sexChromosomes.index = i;\n      }\n    } else if (chr === 'X') {\n      ideo.sexChromosomes.list.push(chr, chr);\n      ideo.sexChromosomes.index = i;\n    }\n  }\n}\n\nexport {drawSexChromosomes, setSexChromosomes};\n","/**\n * @fileoverview Methods to convert to and from different types of coordinates.\n *\n * Ideogram.js uses multiple coordinate systems, e.g. base pairs (bp) and\n * pixels (px).  These methods interconvert between those coordinate systems.\n *\n * TODO:\n * - Add methods to interconvert between ISCN coordinates and base pairs,\n * pixels.\n */\n\nfunction throwBpToPxError(bp, chr, band) {\n  throw new Error(\n    'Base pair out of range.  ' +\n    'bp: ' + bp + '; length of chr' + chr.name + ': ' + band.bp.stop\n  );\n}\n\nfunction getPx(chr, bp) {\n  var i, px, band, bpToIscnScale, iscn, iscnStart, iscnStop, iscnLength,\n    bpStart, bpStop, bpLength, pxStart, pxLength;\n\n  for (i = 0; i < chr.bands.length; i++) {\n    band = chr.bands[i];\n    bpStart = band.bp.start;\n    bpStop = band.bp.stop;\n    bpLength = bpStop - bpStart;\n    iscnStart = band.iscn.start;\n    iscnStop = band.iscn.stop;\n    iscnLength = iscnStop - iscnStart;\n    pxStart = band.px.start;\n    pxLength = band.px.width;\n\n    if (bp >= bpStart && bp <= bpStop) {\n      bpToIscnScale = iscnLength / bpLength;\n      iscn = iscnStart + (bp - bpStart) * bpToIscnScale;\n      px = pxStart + (pxLength * (iscn - iscnStart) / (iscnLength));\n\n      return [px, band];\n    }\n  }\n  return [null, band];\n}\n\n/**\n * Converts base pair coordinates to pixel offsets.\n * Bp-to-pixel scales differ among cytogenetic bands.\n *\n * For example, if we want to depict a gene on a chromosome, then we need\n * to convert the gene's location in base pairs to a location in pixels offset\n * from the start of the chromosome.\n */\nfunction convertBpToPx(chr, bp) {\n  var band, px;\n\n  if (chr.bands.length > 1) {\n    [px, band] = getPx(chr, bp);\n    if (px !== null) return px;\n  } else if (bp >= 1 && bp <= chr.length) {\n    px = chr.scale.bp * bp;\n    return px;\n  }\n\n  throwBpToPxError(bp, chr, band);\n}\n\nfunction throwPxToBpError(px, chr, pxStop) {\n  throw new Error(\n    'Pixel out of range.  ' +\n    'px: ' + px + '; length of chr' + chr.name + ': ' + pxStop\n  );\n}\n\nfunction getBp(iscnStop, iscnStart, px, pxStop, pxStart, band, iscnLength) {\n  var pxLength, bpLength, pxToIscnScale, iscn, bp;\n\n  iscnLength = iscnStop - iscnStart;\n  pxLength = pxStop - pxStart;\n  bpLength = band.bp.stop - band.bp.start;\n\n  pxToIscnScale = iscnLength / pxLength;\n  iscn = iscnStart + (px - pxStart) * pxToIscnScale;\n\n  bp = band.bp.start + (bpLength * (iscn - iscnStart) / iscnLength);\n\n  return Math.round(bp);\n}\n\n/**\n * Converts pixel offsets to base pair coordinates.\n * Pixel-to-bp scales differ among cytogenetic bands.\n *\n * For example, if we want to determine the genomic location a user clicked on\n * (e.g. when creating a brush / sliding window region), then we need to\n * convert pixels to base pairs.\n */\nfunction convertPxToBp(chr, px) {\n  var i, band, bp, pxStart, pxStop, iscnStart, iscnStop, iscnLength;\n\n  if (px === 0) {\n    px = chr.bands[0].px.start;\n  }\n\n  for (i = 0; i < chr.bands.length; i++) {\n    band = chr.bands[i];\n\n    pxStart = band.px.start;\n    pxStop = band.px.stop;\n    iscnStart = band.iscn.start;\n    iscnStop = band.iscn.stop;\n\n    if (px >= pxStart && px <= pxStop) {\n      bp = getBp(iscnStop, iscnStart, px, pxStop, pxStart, band, iscnLength);\n      return bp;\n    }\n  }\n  throwPxToBpError(px, chr, pxStop);\n}\n\nexport {convertBpToPx, convertPxToBp};\n","let array8 = arrayUntyped,\n    array16 = arrayUntyped,\n    array32 = arrayUntyped,\n    arrayLengthen = arrayLengthenUntyped,\n    arrayWiden = arrayWidenUntyped;\nif (typeof Uint8Array !== \"undefined\") {\n  array8 = function(n) { return new Uint8Array(n); };\n  array16 = function(n) { return new Uint16Array(n); };\n  array32 = function(n) { return new Uint32Array(n); };\n\n  arrayLengthen = function(array, length) {\n    if (array.length >= length) return array;\n    var copy = new array.constructor(length);\n    copy.set(array);\n    return copy;\n  };\n\n  arrayWiden = function(array, width) {\n    var copy;\n    switch (width) {\n      case 16: copy = array16(array.length); break;\n      case 32: copy = array32(array.length); break;\n      default: throw new Error(\"invalid array width!\");\n    }\n    copy.set(array);\n    return copy;\n  };\n}\n\nfunction arrayUntyped(n) {\n  var array = new Array(n), i = -1;\n  while (++i < n) array[i] = 0;\n  return array;\n}\n\nfunction arrayLengthenUntyped(array, length) {\n  var n = array.length;\n  while (n < length) array[n++] = 0;\n  return array;\n}\n\nfunction arrayWidenUntyped(array, width) {\n  if (width > 32) throw new Error(\"invalid array width!\");\n  return array;\n}\n\n// An arbitrarily-wide array of bitmasks\nfunction bitarray(n) {\n  this.length = n;\n  this.subarrays = 1;\n  this.width = 8;\n  this.masks = {\n    0: 0\n  }\n\n  this[0] = array8(n);\n}\n\nbitarray.prototype.lengthen = function(n) {\n  var i, len;\n  for (i = 0, len = this.subarrays; i < len; ++i) {\n    this[i] = arrayLengthen(this[i], n);\n  }\n  this.length = n;\n};\n\n// Reserve a new bit index in the array, returns {offset, one}\nbitarray.prototype.add = function() {\n  var m, w, one, i, len;\n\n  for (i = 0, len = this.subarrays; i < len; ++i) {\n    m = this.masks[i];\n    w = this.width - (32 * i);\n    // isolate the rightmost zero bit and return it as an unsigned int of 32 bits, if NaN or -1, return a 0 \n    one = (~m & (m + 1)) >>> 0;\n\n    if (w >= 32 && !one) {\n      continue;\n    }\n\n    if (w < 32 && (one & (1 << w))) {\n      // widen this subarray\n      this[i] = arrayWiden(this[i], w <<= 1);\n      this.width = 32 * i + w;\n    }\n\n    this.masks[i] |= one;\n\n    return {\n      offset: i,\n      one: one\n    };\n  }\n\n  // add a new subarray\n  this[this.subarrays] = array8(this.length);\n  this.masks[this.subarrays] = 1;\n  this.width += 8;\n  return {\n    offset: this.subarrays++,\n    one: 1\n  };\n};\n\n// Copy record from index src to index dest\nbitarray.prototype.copy = function(dest, src) {\n  var i, len;\n  for (i = 0, len = this.subarrays; i < len; ++i) {\n    this[i][dest] = this[i][src];\n  }\n};\n\n// Truncate the array to the given length\nbitarray.prototype.truncate = function(n) {\n  var i, len;\n  for (i = 0, len = this.subarrays; i < len; ++i) {\n    for (var j = this.length - 1; j >= n; j--) {\n      this[i][j] = 0;\n    }\n  }\n  this.length = n;\n};\n\n// Checks that all bits for the given index are 0\nbitarray.prototype.zero = function(n) {\n  var i, len;\n  for (i = 0, len = this.subarrays; i < len; ++i) {\n    if (this[i][n]) {\n      return false;\n    }\n  }\n  return true;\n};\n\n// Checks that all bits for the given index are 0 except for possibly one\nbitarray.prototype.zeroExcept = function(n, offset, zero) {\n  var i, len;\n  for (i = 0, len = this.subarrays; i < len; ++i) {\n    if (i === offset ? this[i][n] & zero : this[i][n]) {\n      return false;\n    }\n  }\n  return true;\n};\n\n// Checks that all bits for the given index are 0 except for the specified mask.\n// The mask should be an array of the same size as the filter subarrays width.\nbitarray.prototype.zeroExceptMask = function(n, mask) {\n  var i, len;\n  for (i = 0, len = this.subarrays; i < len; ++i) {\n    if (this[i][n] & mask[i]) {\n      return false;\n    }\n  }\n  return true;\n}\n\n// Checks that only the specified bit is set for the given index\nbitarray.prototype.only = function(n, offset, one) {\n  var i, len;\n  for (i = 0, len = this.subarrays; i < len; ++i) {\n    if (this[i][n] != (i === offset ? one : 0)) {\n      return false;\n    }\n  }\n  return true;\n};\n\n// Checks that only the specified bit is set for the given index except for possibly one other\nbitarray.prototype.onlyExcept = function(n, offset, zero, onlyOffset, onlyOne) {\n  var mask;\n  var i, len;\n  for (i = 0, len = this.subarrays; i < len; ++i) {\n    mask = this[i][n];\n    if (i === offset)\n      mask &= zero;\n    if (mask != (i === onlyOffset ? onlyOne : 0)) {\n      return false;\n    }\n  }\n  return true;\n};\n\nexport default {\n  array8: arrayUntyped,\n  array16: arrayUntyped,\n  array32: arrayUntyped,\n  arrayLengthen: arrayLengthenUntyped,\n  arrayWiden: arrayWidenUntyped,\n  bitarray: bitarray\n};\n","const filterExact = (bisect, value) => {\n  return function(values) {\n    var n = values.length;\n    return [bisect.left(values, value, 0, n), bisect.right(values, value, 0, n)];\n  };\n}\n\nconst filterRange = (bisect, range) => {\n  var min = range[0],\n      max = range[1];\n  return function(values) {\n    var n = values.length;\n    return [bisect.left(values, min, 0, n), bisect.left(values, max, 0, n)];\n  };\n}\n\nconst filterAll = values => {\n  return [0, values.length];\n}\n\nexport default {\n  filterExact,\n  filterRange,\n  filterAll\n};\n","export default d => {\n  return d;\n};\n","export default () =>  {\n  return null;\n}\n","export default () => {\n  return 0;\n}\n","import identity from './identity';\n\nfunction heap_by(f) {\n\n  // Builds a binary heap within the specified array a[lo:hi]. The heap has the\n  // property such that the parent a[lo+i] is always less than or equal to its\n  // two children: a[lo+2*i+1] and a[lo+2*i+2].\n  function heap(a, lo, hi) {\n    var n = hi - lo,\n        i = (n >>> 1) + 1;\n    while (--i > 0) sift(a, i, n, lo);\n    return a;\n  }\n\n  // Sorts the specified array a[lo:hi] in descending order, assuming it is\n  // already a heap.\n  function sort(a, lo, hi) {\n    var n = hi - lo,\n        t;\n    while (--n > 0) t = a[lo], a[lo] = a[lo + n], a[lo + n] = t, sift(a, 1, n, lo);\n    return a;\n  }\n\n  // Sifts the element a[lo+i-1] down the heap, where the heap is the contiguous\n  // slice of array a[lo:lo+n]. This method can also be used to update the heap\n  // incrementally, without incurring the full cost of reconstructing the heap.\n  function sift(a, i, n, lo) {\n    var d = a[--lo + i],\n        x = f(d),\n        child;\n    while ((child = i << 1) <= n) {\n      if (child < n && f(a[lo + child]) > f(a[lo + child + 1])) child++;\n      if (x <= f(a[lo + child])) break;\n      a[lo + i] = a[lo + child];\n      i = child;\n    }\n    a[lo + i] = d;\n  }\n\n  heap.sort = sort;\n  return heap;\n}\n\nconst h = heap_by(identity);\nh.by = heap_by;\n\nexport default h;\n","import identity from './identity';\nimport xFilterHeap from './heap';\n\nfunction heapselect_by(f) {\n  var heap = xFilterHeap.by(f);\n\n  // Returns a new array containing the top k elements in the array a[lo:hi].\n  // The returned array is not sorted, but maintains the heap property. If k is\n  // greater than hi - lo, then fewer than k elements will be returned. The\n  // order of elements in a is unchanged by this operation.\n  function heapselect(a, lo, hi, k) {\n    var queue = new Array(k = Math.min(hi - lo, k)),\n        min,\n        i,\n        d;\n\n    for (i = 0; i < k; ++i) queue[i] = a[lo++];\n    heap(queue, 0, k);\n\n    if (lo < hi) {\n      min = f(queue[0]);\n      do {\n        if (f(d = a[lo]) > min) {\n          queue[0] = d;\n          min = f(heap(queue, 0, k)[0]);\n        }\n      } while (++lo < hi);\n    }\n\n    return queue;\n  }\n\n  return heapselect;\n}\n\n\nconst h = heapselect_by(identity);\nh.by = heapselect_by; // assign the raw function to the export as well\n\nexport default h;\n","import identity from './identity';\n\nfunction bisect_by(f) {\n\n  // Locate the insertion point for x in a to maintain sorted order. The\n  // arguments lo and hi may be used to specify a subset of the array which\n  // should be considered; by default the entire array is used. If x is already\n  // present in a, the insertion point will be before (to the left of) any\n  // existing entries. The return value is suitable for use as the first\n  // argument to `array.splice` assuming that a is already sorted.\n  //\n  // The returned insertion point i partitions the array a into two halves so\n  // that all v < x for v in a[lo:i] for the left side and all v >= x for v in\n  // a[i:hi] for the right side.\n  function bisectLeft(a, x, lo, hi) {\n    while (lo < hi) {\n      var mid = lo + hi >>> 1;\n      if (f(a[mid]) < x) lo = mid + 1;\n      else hi = mid;\n    }\n    return lo;\n  }\n\n  // Similar to bisectLeft, but returns an insertion point which comes after (to\n  // the right of) any existing entries of x in a.\n  //\n  // The returned insertion point i partitions the array into two halves so that\n  // all v <= x for v in a[lo:i] for the left side and all v > x for v in\n  // a[i:hi] for the right side.\n  function bisectRight(a, x, lo, hi) {\n    while (lo < hi) {\n      var mid = lo + hi >>> 1;\n      if (x < f(a[mid])) hi = mid;\n      else lo = mid + 1;\n    }\n    return lo;\n  }\n\n  bisectRight.right = bisectRight;\n  bisectRight.left = bisectLeft;\n  return bisectRight;\n}\n\nconst bisect = bisect_by(identity);\nbisect.by = bisect_by; // assign the raw function to the export as well\n\nexport default bisect;\n\n","export default (array, index, deep) => {\n  for (var i = 0, n = index.length, copy = deep ? JSON.parse(JSON.stringify(array)) : new Array(n); i < n; ++i) {\n    copy[i] = array[index[i]];\n  }\n  return copy;\n}\n","const reduceIncrement = p => {\n  return p + 1;\n}\n\nconst reduceDecrement = p => {\n  return p - 1;\n}\n\nconst reduceAdd = f => {\n  return function(p, v) {\n    return p + +f(v);\n  };\n}\n\nconst reduceSubtract = f => {\n  return function(p, v) {\n    return p - f(v);\n  };\n}\n\nexport default {\n  reduceIncrement,\n  reduceDecrement,\n  reduceAdd,\n  reduceSubtract\n};\n","import deep from \"@ranfdev/deepobj\"\n// Note(cg): result was previsouly using lodash.result, not ESM compatible.\n \nconst get = (obj, prop) => {\n  const value = obj[prop];\n  return (typeof value === 'function') ? value.call(obj) : value;\n}\n\n/**\n * get value of object at a deep path.\n * if the resolved value is a function,\n * it's invoked with the `this` binding of \n * its parent object and its result is returned. \n *  \n * @param  {Object} obj  the object (e.g. { 'a': [{ 'b': { 'c1': 3, 'c2': 4} }], 'd': {e:1} }; )\n * @param  {String} path deep path (e.g. `d.e`` or `a[0].b.c1`. Dot notation (a.0.b)is also supported)\n * @return {Any}      the resolved value\n */\nconst reg = /\\[([\\w\\d]+)\\]/g;\nexport default (obj, path) => {\n  return deep(get, obj, path.replace(reg, '.$1'))\n}\n","export default function(t,e,i,n,r){for(r in n=(i=i.split(\".\")).splice(-1,1),i)e=e[i[r]]=e[i[r]]||{};return t(e,n)};\n//# sourceMappingURL=deepobj.m.js.map\n","import xfilterArray from './array';\nimport xfilterFilter from './filter';\nimport cr_identity from './identity';\nimport cr_null from './null';\nimport cr_zero from './zero';\nimport xfilterHeapselect from './heapselect';\nimport xfilterHeap from './heap';\nimport bisect from './bisect';\nimport permute from './permute';\nimport xfilterReduce from './reduce';\nimport result from './result';\n\n// constants\nvar REMOVED_INDEX = -1;\n\ncrossfilter.heap = xfilterHeap;\ncrossfilter.heapselect = xfilterHeapselect;\ncrossfilter.bisect = bisect;\ncrossfilter.permute = permute;\nexport default crossfilter;\n\nfunction crossfilter() {\n  var crossfilter = {\n    add: add,\n    remove: removeData,\n    dimension: dimension,\n    groupAll: groupAll,\n    size: size,\n    all: all,\n    allFiltered: allFiltered,\n    onChange: onChange,\n    isElementFiltered: isElementFiltered\n  };\n\n  var data = [], // the records\n      n = 0, // the number of records; data.length\n      filters, // 1 is filtered out\n      filterListeners = [], // when the filters change\n      dataListeners = [], // when data is added\n      removeDataListeners = [], // when data is removed\n      callbacks = [];\n\n  filters = new xfilterArray.bitarray(0);\n\n  // Adds the specified new records to this crossfilter.\n  function add(newData) {\n    var n0 = n,\n        n1 = newData.length;\n\n    // If there's actually new data to add…\n    // Merge the new data into the existing data.\n    // Lengthen the filter bitset to handle the new records.\n    // Notify listeners (dimensions and groups) that new data is available.\n    if (n1) {\n      data = data.concat(newData);\n      filters.lengthen(n += n1);\n      dataListeners.forEach(function(l) { l(newData, n0, n1); });\n      triggerOnChange('dataAdded');\n    }\n\n    return crossfilter;\n  }\n\n  // Removes all records that match the current filters, or if a predicate function is passed,\n  // removes all records matching the predicate (ignoring filters).\n  function removeData(predicate) {\n    var // Mapping from old record indexes to new indexes (after records removed)\n        newIndex = new Array(n),\n        removed = [],\n        usePred = typeof predicate === 'function',\n        shouldRemove = function (i) {\n          return usePred ? predicate(data[i], i) : filters.zero(i)\n        };\n\n    for (var index1 = 0, index2 = 0; index1 < n; ++index1) {\n      if ( shouldRemove(index1) ) {\n        removed.push(index1);\n        newIndex[index1] = REMOVED_INDEX;\n      } else {\n        newIndex[index1] = index2++;\n      }\n    }\n\n    // Remove all matching records from groups.\n    filterListeners.forEach(function(l) { l(-1, -1, [], removed, true); });\n\n    // Update indexes.\n    removeDataListeners.forEach(function(l) { l(newIndex); });\n\n    // Remove old filters and data by overwriting.\n    for (var index3 = 0, index4 = 0; index3 < n; ++index3) {\n      if ( newIndex[index3] !== REMOVED_INDEX ) {\n        if (index3 !== index4) filters.copy(index4, index3), data[index4] = data[index3];\n        ++index4;\n      }\n    }\n\n    data.length = n = index4;\n    filters.truncate(index4);\n    triggerOnChange('dataRemoved');\n  }\n\n  function maskForDimensions(dimensions) {\n    var n,\n        d,\n        len,\n        id,\n        mask = Array(filters.subarrays);\n    for (n = 0; n < filters.subarrays; n++) { mask[n] = ~0; }\n    for (d = 0, len = dimensions.length; d < len; d++) {\n      // The top bits of the ID are the subarray offset and the lower bits are the bit\n      // offset of the \"one\" mask.\n      id = dimensions[d].id();\n      mask[id >> 7] &= ~(0x1 << (id & 0x3f));\n    }\n    return mask;\n  }\n\n  // Return true if the data element at index i is filtered IN.\n  // Optionally, ignore the filters of any dimensions in the ignore_dimensions list.\n  function isElementFiltered(i, ignore_dimensions) {\n    var mask = maskForDimensions(ignore_dimensions || []);\n    return filters.zeroExceptMask(i,mask);\n  }\n\n  // Adds a new dimension with the specified value accessor function.\n  function dimension(value, iterable) {\n\n    if (typeof value === 'string') {\n      var accessorPath = value;\n      value = function(d) { return result(d, accessorPath); };\n    }\n\n    var dimension = {\n      filter: filter,\n      filterExact: filterExact,\n      filterRange: filterRange,\n      filterFunction: filterFunction,\n      filterAll: filterAll,\n      currentFilter: currentFilter,\n      hasCurrentFilter: hasCurrentFilter,\n      top: top,\n      bottom: bottom,\n      group: group,\n      groupAll: groupAll,\n      dispose: dispose,\n      remove: dispose, // for backwards-compatibility\n      accessor: value,\n      id: function() { return id; }\n    };\n\n    var one, // lowest unset bit as mask, e.g., 00001000\n        zero, // inverted one, e.g., 11110111\n        offset, // offset into the filters arrays\n        id, // unique ID for this dimension (reused when dimensions are disposed)\n        values, // sorted, cached array\n        index, // maps sorted value index -> record index (in data)\n        newValues, // temporary array storing newly-added values\n        newIndex, // temporary array storing newly-added index\n        iterablesIndexCount,\n        iterablesIndexFilterStatus,\n        iterablesEmptyRows = [],\n        sortRange = function(n) {\n          return cr_range(n).sort(function(A, B) {\n            var a = newValues[A], b = newValues[B];\n            return a < b ? -1 : a > b ? 1 : A - B;\n          });\n        },\n        refilter = xfilterFilter.filterAll, // for recomputing filter\n        refilterFunction, // the custom filter function in use\n        filterValue, // the value used for filtering (value, array, function or undefined)\n        filterValuePresent, // true if filterValue contains something\n        indexListeners = [], // when data is added\n        dimensionGroups = [],\n        lo0 = 0,\n        hi0 = 0,\n        t = 0,\n        k;\n\n    // Updating a dimension is a two-stage process. First, we must update the\n    // associated filters for the newly-added records. Once all dimensions have\n    // updated their filters, the groups are notified to update.\n    dataListeners.unshift(preAdd);\n    dataListeners.push(postAdd);\n\n    removeDataListeners.push(removeData);\n\n    // Add a new dimension in the filter bitmap and store the offset and bitmask.\n    var tmp = filters.add();\n    offset = tmp.offset;\n    one = tmp.one;\n    zero = ~one;\n\n    // Create a unique ID for the dimension\n    // IDs will be re-used if dimensions are disposed.\n    // For internal use the ID is the subarray offset shifted left 7 bits or'd with the\n    // bit offset of the set bit in the dimension's \"one\" mask.\n    id = (offset << 7) | (Math.log(one) / Math.log(2));\n\n    preAdd(data, 0, n);\n    postAdd(data, 0, n);\n\n    // Incorporates the specified new records into this dimension.\n    // This function is responsible for updating filters, values, and index.\n    function preAdd(newData, n0, n1) {\n      var newIterablesIndexCount,\n          newIterablesIndexFilterStatus;\n\n      if (iterable){\n        // Count all the values\n        t = 0;\n        j = 0;\n        k = [];\n\n        for (var i0 = 0; i0 < newData.length; i0++) {\n          for(j = 0, k = value(newData[i0]); j < k.length; j++) {\n            t++;\n          }\n        }\n\n        newValues = [];\n        newIterablesIndexCount = cr_range(newData.length);\n        newIterablesIndexFilterStatus = cr_index(t,1);\n        var unsortedIndex = cr_range(t);\n\n        for (var l = 0, index1 = 0; index1 < newData.length; index1++) {\n          k = value(newData[index1])\n          //\n          if(!k.length){\n            newIterablesIndexCount[index1] = 0;\n            iterablesEmptyRows.push(index1 + n0);\n            continue;\n          }\n          newIterablesIndexCount[index1] = k.length\n          for (j = 0; j < k.length; j++) {\n            newValues.push(k[j]);\n            unsortedIndex[l] = index1;\n            l++;\n          }\n        }\n\n        // Create the Sort map used to sort both the values and the valueToData indices\n        var sortMap = sortRange(t);\n\n        // Use the sortMap to sort the newValues\n        newValues = permute(newValues, sortMap);\n\n\n        // Use the sortMap to sort the unsortedIndex map\n        // newIndex should be a map of sortedValue -> crossfilterData\n        newIndex = permute(unsortedIndex, sortMap)\n\n      } else{\n        // Permute new values into natural order using a standard sorted index.\n        newValues = newData.map(value);\n        newIndex = sortRange(n1);\n        newValues = permute(newValues, newIndex);\n      }\n\n      // Bisect newValues to determine which new records are selected.\n      var bounds = refilter(newValues), lo1 = bounds[0], hi1 = bounds[1];\n\n      var index2, index3, index4;\n      if(iterable) {\n        n1 = t;\n        if (refilterFunction) {\n          for (index2 = 0; index2 < n1; ++index2) {\n            if (!refilterFunction(newValues[index2], index2)) {\n              if(--newIterablesIndexCount[newIndex[index2]] === 0) {\n                filters[offset][newIndex[index2] + n0] |= one;\n              }\n              newIterablesIndexFilterStatus[index2] = 1;\n            }\n          }\n        } else {\n          for (index3 = 0; index3 < lo1; ++index3) {\n            if(--newIterablesIndexCount[newIndex[index3]] === 0) {\n              filters[offset][newIndex[index3] + n0] |= one;\n            }\n            newIterablesIndexFilterStatus[index3] = 1;\n          }\n          for (index4 = hi1; index4 < n1; ++index4) {\n            if(--newIterablesIndexCount[newIndex[index4]] === 0) {\n              filters[offset][newIndex[index4] + n0] |= one;\n            }\n            newIterablesIndexFilterStatus[index4] = 1;\n          }\n        }\n      } else {\n        if (refilterFunction) {\n          for (index2 = 0; index2 < n1; ++index2) {\n            if (!refilterFunction(newValues[index2], index2)) {\n              filters[offset][newIndex[index2] + n0] |= one;\n            }\n          }\n        } else {\n          for (index3 = 0; index3 < lo1; ++index3) {\n            filters[offset][newIndex[index3] + n0] |= one;\n          }\n          for (index4 = hi1; index4 < n1; ++index4) {\n            filters[offset][newIndex[index4] + n0] |= one;\n          }\n        }\n      }\n\n      // If this dimension previously had no data, then we don't need to do the\n      // more expensive merge operation; use the new values and index as-is.\n      if (!n0) {\n        values = newValues;\n        index = newIndex;\n        iterablesIndexCount = newIterablesIndexCount;\n        iterablesIndexFilterStatus = newIterablesIndexFilterStatus;\n        lo0 = lo1;\n        hi0 = hi1;\n        return;\n      }\n\n\n\n      var oldValues = values,\n        oldIndex = index,\n        oldIterablesIndexFilterStatus = iterablesIndexFilterStatus,\n        old_n0,\n        i1 = 0;\n\n      i0 = 0;\n\n      if(iterable){\n        old_n0 = n0\n        n0 = oldValues.length;\n        n1 = t\n      }\n\n      // Otherwise, create new arrays into which to merge new and old.\n      values = iterable ? new Array(n0 + n1) : new Array(n);\n      index = iterable ? new Array(n0 + n1) : cr_index(n, n);\n      if(iterable) iterablesIndexFilterStatus = cr_index(n0 + n1, 1);\n\n      // Concatenate the newIterablesIndexCount onto the old one.\n      if(iterable) {\n        var oldiiclength = iterablesIndexCount.length;\n        iterablesIndexCount = xfilterArray.arrayLengthen(iterablesIndexCount, n);\n        for(var j=0; j+oldiiclength < n; j++) {\n          iterablesIndexCount[j+oldiiclength] = newIterablesIndexCount[j];\n        }\n      }\n\n      // Merge the old and new sorted values, and old and new index.\n      var index5 = 0;\n      for (; i0 < n0 && i1 < n1; ++index5) {\n        if (oldValues[i0] < newValues[i1]) {\n          values[index5] = oldValues[i0];\n          if(iterable) iterablesIndexFilterStatus[index5] = oldIterablesIndexFilterStatus[i0];\n          index[index5] = oldIndex[i0++];\n        } else {\n          values[index5] = newValues[i1];\n          if(iterable) iterablesIndexFilterStatus[index5] = newIterablesIndexFilterStatus[i1];\n          index[index5] = newIndex[i1++] + (iterable ? old_n0 : n0);\n        }\n      }\n\n      // Add any remaining old values.\n      for (; i0 < n0; ++i0, ++index5) {\n        values[index5] = oldValues[i0];\n        if(iterable) iterablesIndexFilterStatus[index5] = oldIterablesIndexFilterStatus[i0];\n        index[index5] = oldIndex[i0];\n      }\n\n      // Add any remaining new values.\n      for (; i1 < n1; ++i1, ++index5) {\n        values[index5] = newValues[i1];\n        if(iterable) iterablesIndexFilterStatus[index5] = newIterablesIndexFilterStatus[i1];\n        index[index5] = newIndex[i1] + (iterable ? old_n0 : n0);\n      }\n\n      // Bisect again to recompute lo0 and hi0.\n      bounds = refilter(values), lo0 = bounds[0], hi0 = bounds[1];\n    }\n\n    // When all filters have updated, notify index listeners of the new values.\n    function postAdd(newData, n0, n1) {\n      indexListeners.forEach(function(l) { l(newValues, newIndex, n0, n1); });\n      newValues = newIndex = null;\n    }\n\n    function removeData(reIndex) {\n      if (iterable) {\n        for (var i0 = 0, i1 = 0; i0 < iterablesEmptyRows.length; i0++) {\n          if (reIndex[iterablesEmptyRows[i0]] !== REMOVED_INDEX) {\n            iterablesEmptyRows[i1] = reIndex[iterablesEmptyRows[i0]];\n            i1++;\n          }\n        }\n        iterablesEmptyRows.length = i1;\n        for (i0 = 0, i1 = 0; i0 < n; i0++) {\n          if (reIndex[i0] !== REMOVED_INDEX) {\n            if (i1 !== i0) iterablesIndexCount[i1] = iterablesIndexCount[i0];\n            i1++;\n          }\n        }\n        iterablesIndexCount = iterablesIndexCount.slice(0, i1);\n      }\n      // Rewrite our index, overwriting removed values\n      var n0 = values.length;\n      for (var i = 0, j = 0, oldDataIndex; i < n0; ++i) {\n        oldDataIndex = index[i];\n        if (reIndex[oldDataIndex] !== REMOVED_INDEX) {\n          if (i !== j) values[j] = values[i];\n          index[j] = reIndex[oldDataIndex];\n          if (iterable) {\n            iterablesIndexFilterStatus[j] = iterablesIndexFilterStatus[i];\n          }\n          ++j;\n        }\n      }\n      values.length = j;\n      if (iterable) iterablesIndexFilterStatus = iterablesIndexFilterStatus.slice(0, j);\n      while (j < n0) index[j++] = 0;\n\n      // Bisect again to recompute lo0 and hi0.\n      var bounds = refilter(values);\n      lo0 = bounds[0], hi0 = bounds[1];\n    }\n\n    // Updates the selected values based on the specified bounds [lo, hi].\n    // This implementation is used by all the public filter methods.\n    function filterIndexBounds(bounds) {\n\n      var lo1 = bounds[0],\n          hi1 = bounds[1];\n\n      if (refilterFunction) {\n        refilterFunction = null;\n        filterIndexFunction(function(d, i) { return lo1 <= i && i < hi1; }, bounds[0] === 0 && bounds[1] === values.length);\n        lo0 = lo1;\n        hi0 = hi1;\n        return dimension;\n      }\n\n      var i,\n          j,\n          k,\n          added = [],\n          removed = [],\n          valueIndexAdded = [],\n          valueIndexRemoved = [];\n\n\n      // Fast incremental update based on previous lo index.\n      if (lo1 < lo0) {\n        for (i = lo1, j = Math.min(lo0, hi1); i < j; ++i) {\n          added.push(index[i]);\n          valueIndexAdded.push(i);\n        }\n      } else if (lo1 > lo0) {\n        for (i = lo0, j = Math.min(lo1, hi0); i < j; ++i) {\n          removed.push(index[i]);\n          valueIndexRemoved.push(i);\n        }\n      }\n\n      // Fast incremental update based on previous hi index.\n      if (hi1 > hi0) {\n        for (i = Math.max(lo1, hi0), j = hi1; i < j; ++i) {\n          added.push(index[i]);\n          valueIndexAdded.push(i);\n        }\n      } else if (hi1 < hi0) {\n        for (i = Math.max(lo0, hi1), j = hi0; i < j; ++i) {\n          removed.push(index[i]);\n          valueIndexRemoved.push(i);\n        }\n      }\n\n      if(!iterable) {\n        // Flip filters normally.\n\n        for(i=0; i<added.length; i++) {\n          filters[offset][added[i]] ^= one;\n        }\n\n        for(i=0; i<removed.length; i++) {\n          filters[offset][removed[i]] ^= one;\n        }\n\n      } else {\n        // For iterables, we need to figure out if the row has been completely removed vs partially included\n        // Only count a row as added if it is not already being aggregated. Only count a row\n        // as removed if the last element being aggregated is removed.\n\n        var newAdded = [];\n        var newRemoved = [];\n        for (i = 0; i < added.length; i++) {\n          iterablesIndexCount[added[i]]++\n          iterablesIndexFilterStatus[valueIndexAdded[i]] = 0;\n          if(iterablesIndexCount[added[i]] === 1) {\n            filters[offset][added[i]] ^= one;\n            newAdded.push(added[i]);\n          }\n        }\n        for (i = 0; i < removed.length; i++) {\n          iterablesIndexCount[removed[i]]--\n          iterablesIndexFilterStatus[valueIndexRemoved[i]] = 1;\n          if(iterablesIndexCount[removed[i]] === 0) {\n            filters[offset][removed[i]] ^= one;\n            newRemoved.push(removed[i]);\n          }\n        }\n\n        added = newAdded;\n        removed = newRemoved;\n\n        // Now handle empty rows.\n        if(refilter === xfilterFilter.filterAll) {\n          for(i = 0; i < iterablesEmptyRows.length; i++) {\n            if((filters[offset][k = iterablesEmptyRows[i]] & one)) {\n              // Was not in the filter, so set the filter and add\n              filters[offset][k] ^= one;\n              added.push(k);\n            }\n          }\n        } else {\n          // filter in place - remove empty rows if necessary\n          for(i = 0; i < iterablesEmptyRows.length; i++) {\n            if(!(filters[offset][k = iterablesEmptyRows[i]] & one)) {\n              // Was in the filter, so set the filter and remove\n              filters[offset][k] ^= one;\n              removed.push(k);\n            }\n          }\n        }\n      }\n\n      lo0 = lo1;\n      hi0 = hi1;\n      filterListeners.forEach(function(l) { l(one, offset, added, removed); });\n      triggerOnChange('filtered');\n      return dimension;\n    }\n\n    // Filters this dimension using the specified range, value, or null.\n    // If the range is null, this is equivalent to filterAll.\n    // If the range is an array, this is equivalent to filterRange.\n    // Otherwise, this is equivalent to filterExact.\n    function filter(range) {\n      return range == null\n          ? filterAll() : Array.isArray(range)\n          ? filterRange(range) : typeof range === \"function\"\n          ? filterFunction(range)\n          : filterExact(range);\n    }\n\n    // Filters this dimension to select the exact value.\n    function filterExact(value) {\n      filterValue = value;\n      filterValuePresent = true;\n      return filterIndexBounds((refilter = xfilterFilter.filterExact(bisect, value))(values));\n    }\n\n    // Filters this dimension to select the specified range [lo, hi].\n    // The lower bound is inclusive, and the upper bound is exclusive.\n    function filterRange(range) {\n      filterValue = range;\n      filterValuePresent = true;\n      return filterIndexBounds((refilter = xfilterFilter.filterRange(bisect, range))(values));\n    }\n\n    // Clears any filters on this dimension.\n    function filterAll() {\n      filterValue = undefined;\n      filterValuePresent = false;\n      return filterIndexBounds((refilter = xfilterFilter.filterAll)(values));\n    }\n\n    // Filters this dimension using an arbitrary function.\n    function filterFunction(f) {\n      filterValue = f;\n      filterValuePresent = true;\n      \n      refilterFunction = f;\n      refilter = xfilterFilter.filterAll;\n\n      filterIndexFunction(f, false);\n\n      var bounds = refilter(values);\n      lo0 = bounds[0], hi0 = bounds[1];\n\n      return dimension;\n    }\n\n    function filterIndexFunction(f, filterAll) {\n      var i,\n          k,\n          x,\n          added = [],\n          removed = [],\n          valueIndexAdded = [],\n          valueIndexRemoved = [],\n          indexLength = values.length;\n\n      if(!iterable) {\n        for (i = 0; i < indexLength; ++i) {\n          if (!(filters[offset][k = index[i]] & one) ^ !!(x = f(values[i], i))) {\n            if (x) added.push(k);\n            else removed.push(k);\n          }\n        }\n      }\n\n      if(iterable) {\n        for(i=0; i < indexLength; ++i) {\n          if(f(values[i], i)) {\n            added.push(index[i]);\n            valueIndexAdded.push(i);\n          } else {\n            removed.push(index[i]);\n            valueIndexRemoved.push(i);\n          }\n        }\n      }\n\n      if(!iterable) {\n        for(i=0; i<added.length; i++) {\n          if(filters[offset][added[i]] & one) filters[offset][added[i]] &= zero;\n        }\n\n        for(i=0; i<removed.length; i++) {\n          if(!(filters[offset][removed[i]] & one)) filters[offset][removed[i]] |= one;\n        }\n      } else {\n\n        var newAdded = [];\n        var newRemoved = [];\n        for (i = 0; i < added.length; i++) {\n          // First check this particular value needs to be added\n          if(iterablesIndexFilterStatus[valueIndexAdded[i]] === 1) {\n            iterablesIndexCount[added[i]]++\n            iterablesIndexFilterStatus[valueIndexAdded[i]] = 0;\n            if(iterablesIndexCount[added[i]] === 1) {\n              filters[offset][added[i]] ^= one;\n              newAdded.push(added[i]);\n            }\n          }\n        }\n        for (i = 0; i < removed.length; i++) {\n          // First check this particular value needs to be removed\n          if(iterablesIndexFilterStatus[valueIndexRemoved[i]] === 0) {\n            iterablesIndexCount[removed[i]]--\n            iterablesIndexFilterStatus[valueIndexRemoved[i]] = 1;\n            if(iterablesIndexCount[removed[i]] === 0) {\n              filters[offset][removed[i]] ^= one;\n              newRemoved.push(removed[i]);\n            }\n          }\n        }\n\n        added = newAdded;\n        removed = newRemoved;\n\n        // Now handle empty rows.\n        if(filterAll) {\n          for(i = 0; i < iterablesEmptyRows.length; i++) {\n            if((filters[offset][k = iterablesEmptyRows[i]] & one)) {\n              // Was not in the filter, so set the filter and add\n              filters[offset][k] ^= one;\n              added.push(k);\n            }\n          }\n        } else {\n          // filter in place - remove empty rows if necessary\n          for(i = 0; i < iterablesEmptyRows.length; i++) {\n            if(!(filters[offset][k = iterablesEmptyRows[i]] & one)) {\n              // Was in the filter, so set the filter and remove\n              filters[offset][k] ^= one;\n              removed.push(k);\n            }\n          }\n        }\n      }\n\n      filterListeners.forEach(function(l) { l(one, offset, added, removed); });\n      triggerOnChange('filtered');\n    }\n    \n    function currentFilter() {\n      return filterValue;\n    }\n    \n    function hasCurrentFilter() {\n      return filterValuePresent;\n    }\n\n    // Returns the top K selected records based on this dimension's order.\n    // Note: observes this dimension's filter, unlike group and groupAll.\n    function top(k, top_offset) {\n      var array = [],\n          i = hi0,\n          j,\n          toSkip = 0;\n\n      if(top_offset && top_offset > 0) toSkip = top_offset;\n\n      while (--i >= lo0 && k > 0) {\n        if (filters.zero(j = index[i])) {\n          if(toSkip > 0) {\n            //skip matching row\n            --toSkip;\n          } else {\n            array.push(data[j]);\n            --k;\n          }\n        }\n      }\n\n      if(iterable){\n        for(i = 0; i < iterablesEmptyRows.length && k > 0; i++) {\n          // Add row with empty iterable column at the end\n          if(filters.zero(j = iterablesEmptyRows[i])) {\n            if(toSkip > 0) {\n              //skip matching row\n              --toSkip;\n            } else {\n              array.push(data[j]);\n              --k;\n            }\n          }\n        }\n      }\n\n      return array;\n    }\n\n    // Returns the bottom K selected records based on this dimension's order.\n    // Note: observes this dimension's filter, unlike group and groupAll.\n    function bottom(k, bottom_offset) {\n      var array = [],\n          i,\n          j,\n          toSkip = 0;\n\n      if(bottom_offset && bottom_offset > 0) toSkip = bottom_offset;\n\n      if(iterable) {\n        // Add row with empty iterable column at the top\n        for(i = 0; i < iterablesEmptyRows.length && k > 0; i++) {\n          if(filters.zero(j = iterablesEmptyRows[i])) {\n            if(toSkip > 0) {\n              //skip matching row\n              --toSkip;\n            } else {\n              array.push(data[j]);\n              --k;\n            }\n          }\n        }\n      }\n\n      i = lo0;\n\n      while (i < hi0 && k > 0) {\n        if (filters.zero(j = index[i])) {\n          if(toSkip > 0) {\n            //skip matching row\n            --toSkip;\n          } else {\n            array.push(data[j]);\n            --k;\n          }\n        }\n        i++;\n      }\n\n      return array;\n    }\n\n    // Adds a new group to this dimension, using the specified key function.\n    function group(key) {\n      var group = {\n        top: top,\n        all: all,\n        reduce: reduce,\n        reduceCount: reduceCount,\n        reduceSum: reduceSum,\n        order: order,\n        orderNatural: orderNatural,\n        size: size,\n        dispose: dispose,\n        remove: dispose // for backwards-compatibility\n      };\n\n      // Ensure that this group will be removed when the dimension is removed.\n      dimensionGroups.push(group);\n\n      var groups, // array of {key, value}\n          groupIndex, // object id ↦ group id\n          groupWidth = 8,\n          groupCapacity = capacity(groupWidth),\n          k = 0, // cardinality\n          select,\n          heap,\n          reduceAdd,\n          reduceRemove,\n          reduceInitial,\n          update = cr_null,\n          reset = cr_null,\n          resetNeeded = true,\n          groupAll = key === cr_null,\n          n0old;\n\n      if (arguments.length < 1) key = cr_identity;\n\n      // The group listens to the crossfilter for when any dimension changes, so\n      // that it can update the associated reduce values. It must also listen to\n      // the parent dimension for when data is added, and compute new keys.\n      filterListeners.push(update);\n      indexListeners.push(add);\n      removeDataListeners.push(removeData);\n\n      // Incorporate any existing data into the grouping.\n      add(values, index, 0, n);\n\n      // Incorporates the specified new values into this group.\n      // This function is responsible for updating groups and groupIndex.\n      function add(newValues, newIndex, n0, n1) {\n\n        if(iterable) {\n          n0old = n0\n          n0 = values.length - newValues.length\n          n1 = newValues.length;\n        }\n\n        var oldGroups = groups,\n            reIndex = iterable ? [] : cr_index(k, groupCapacity),\n            add = reduceAdd,\n            remove = reduceRemove,\n            initial = reduceInitial,\n            k0 = k, // old cardinality\n            i0 = 0, // index of old group\n            i1 = 0, // index of new record\n            j, // object id\n            g0, // old group\n            x0, // old key\n            x1, // new key\n            g, // group to add\n            x; // key of group to add\n\n        // If a reset is needed, we don't need to update the reduce values.\n        if (resetNeeded) add = initial = cr_null;\n        if (resetNeeded) remove = initial = cr_null;\n\n        // Reset the new groups (k is a lower bound).\n        // Also, make sure that groupIndex exists and is long enough.\n        groups = new Array(k), k = 0;\n        if(iterable){\n          groupIndex = k0 ? groupIndex : [];\n        }\n        else{\n          groupIndex = k0 > 1 ? xfilterArray.arrayLengthen(groupIndex, n) : cr_index(n, groupCapacity);\n        }\n\n\n        // Get the first old key (x0 of g0), if it exists.\n        if (k0) x0 = (g0 = oldGroups[0]).key;\n\n        // Find the first new key (x1), skipping NaN keys.\n        while (i1 < n1 && !((x1 = key(newValues[i1])) >= x1)) ++i1;\n\n        // While new keys remain…\n        while (i1 < n1) {\n\n          // Determine the lesser of the two current keys; new and old.\n          // If there are no old keys remaining, then always add the new key.\n          if (g0 && x0 <= x1) {\n            g = g0, x = x0;\n\n            // Record the new index of the old group.\n            reIndex[i0] = k;\n\n            // Retrieve the next old key.\n            g0 = oldGroups[++i0];\n            if (g0) x0 = g0.key;\n          } else {\n            g = {key: x1, value: initial()}, x = x1;\n          }\n\n          // Add the lesser group.\n          groups[k] = g;\n\n          // Add any selected records belonging to the added group, while\n          // advancing the new key and populating the associated group index.\n\n          while (x1 <= x) {\n            j = newIndex[i1] + (iterable ? n0old : n0)\n\n\n            if(iterable){\n              if(groupIndex[j]){\n                groupIndex[j].push(k)\n              }\n              else{\n                groupIndex[j] = [k]\n              }\n            }\n            else{\n              groupIndex[j] = k;\n            }\n\n            // Always add new values to groups. Only remove when not in filter.\n            // This gives groups full information on data life-cycle.\n            g.value = add(g.value, data[j], true);\n            if (!filters.zeroExcept(j, offset, zero)) g.value = remove(g.value, data[j], false);\n            if (++i1 >= n1) break;\n            x1 = key(newValues[i1]);\n          }\n\n          groupIncrement();\n        }\n\n        // Add any remaining old groups that were greater th1an all new keys.\n        // No incremental reduce is needed; these groups have no new records.\n        // Also record the new index of the old group.\n        while (i0 < k0) {\n          groups[reIndex[i0] = k] = oldGroups[i0++];\n          groupIncrement();\n        }\n\n\n        // Fill in gaps with empty arrays where there may have been rows with empty iterables\n        if(iterable){\n          for (var index1 = 0; index1 < n; index1++) {\n            if(!groupIndex[index1]){\n              groupIndex[index1] = [];\n            }\n          }\n        }\n\n        // If we added any new groups before any old groups,\n        // update the group index of all the old records.\n        if(k > i0){\n          if(iterable){\n            for (i0 = 0; i0 < n0old; ++i0) {\n              for (index1 = 0; index1 < groupIndex[i0].length; index1++) {\n                groupIndex[i0][index1] = reIndex[groupIndex[i0][index1]];\n              }\n            }\n          }\n          else{\n            for (i0 = 0; i0 < n0; ++i0) {\n              groupIndex[i0] = reIndex[groupIndex[i0]];\n            }\n          }\n        }\n\n        // Modify the update and reset behavior based on the cardinality.\n        // If the cardinality is less than or equal to one, then the groupIndex\n        // is not needed. If the cardinality is zero, then there are no records\n        // and therefore no groups to update or reset. Note that we also must\n        // change the registered listener to point to the new method.\n        j = filterListeners.indexOf(update);\n        if (k > 1 || iterable) {\n          update = updateMany;\n          reset = resetMany;\n        } else {\n          if (!k && groupAll) {\n            k = 1;\n            groups = [{key: null, value: initial()}];\n          }\n          if (k === 1) {\n            update = updateOne;\n            reset = resetOne;\n          } else {\n            update = cr_null;\n            reset = cr_null;\n          }\n          groupIndex = null;\n        }\n        filterListeners[j] = update;\n\n        // Count the number of added groups,\n        // and widen the group index as needed.\n        function groupIncrement() {\n          if(iterable){\n            k++\n            return\n          }\n          if (++k === groupCapacity) {\n            reIndex = xfilterArray.arrayWiden(reIndex, groupWidth <<= 1);\n            groupIndex = xfilterArray.arrayWiden(groupIndex, groupWidth);\n            groupCapacity = capacity(groupWidth);\n          }\n        }\n      }\n\n      function removeData(reIndex) {\n        if (k > 1 || iterable) {\n          var oldK = k,\n              oldGroups = groups,\n              seenGroups = cr_index(oldK, oldK),\n              i,\n              i0,\n              j;\n\n          // Filter out non-matches by copying matching group index entries to\n          // the beginning of the array.\n          if (!iterable) {\n            for (i = 0, j = 0; i < n; ++i) {\n              if (reIndex[i] !== REMOVED_INDEX) {\n                seenGroups[groupIndex[j] = groupIndex[i]] = 1;\n                ++j;\n              }\n            }\n          } else {\n            for (i = 0, j = 0; i < n; ++i) {\n              if (reIndex[i] !== REMOVED_INDEX) {\n                groupIndex[j] = groupIndex[i];\n                for (i0 = 0; i0 < groupIndex[j].length; i0++) {\n                  seenGroups[groupIndex[j][i0]] = 1;\n                }\n                ++j;\n              }\n            }\n          }\n\n          // Reassemble groups including only those groups that were referred\n          // to by matching group index entries.  Note the new group index in\n          // seenGroups.\n          groups = [], k = 0;\n          for (i = 0; i < oldK; ++i) {\n            if (seenGroups[i]) {\n              seenGroups[i] = k++;\n              groups.push(oldGroups[i]);\n            }\n          }\n\n          if (k > 1 || iterable) {\n            // Reindex the group index using seenGroups to find the new index.\n            if (!iterable) {\n              for (i = 0; i < j; ++i) groupIndex[i] = seenGroups[groupIndex[i]];\n            } else {\n              for (i = 0; i < j; ++i) {\n                for (i0 = 0; i0 < groupIndex[i].length; ++i0) {\n                  groupIndex[i][i0] = seenGroups[groupIndex[i][i0]];\n                }\n              }\n            }\n          } else {\n            groupIndex = null;\n          }\n          filterListeners[filterListeners.indexOf(update)] = k > 1 || iterable\n              ? (reset = resetMany, update = updateMany)\n              : k === 1 ? (reset = resetOne, update = updateOne)\n              : reset = update = cr_null;\n        } else if (k === 1) {\n          if (groupAll) return;\n          for (var index3 = 0; index3 < n; ++index3) if (reIndex[index3] !== REMOVED_INDEX) return;\n          groups = [], k = 0;\n          filterListeners[filterListeners.indexOf(update)] =\n          update = reset = cr_null;\n        }\n      }\n\n      // Reduces the specified selected or deselected records.\n      // This function is only used when the cardinality is greater than 1.\n      // notFilter indicates a crossfilter.add/remove operation.\n      function updateMany(filterOne, filterOffset, added, removed, notFilter) {\n\n        if ((filterOne === one && filterOffset === offset) || resetNeeded) return;\n\n        var i,\n            j,\n            k,\n            n,\n            g;\n\n        if(iterable){\n          // Add the added values.\n          for (i = 0, n = added.length; i < n; ++i) {\n            if (filters.zeroExcept(k = added[i], offset, zero)) {\n              for (j = 0; j < groupIndex[k].length; j++) {\n                g = groups[groupIndex[k][j]];\n                g.value = reduceAdd(g.value, data[k], false, j);\n              }\n            }\n          }\n\n          // Remove the removed values.\n          for (i = 0, n = removed.length; i < n; ++i) {\n            if (filters.onlyExcept(k = removed[i], offset, zero, filterOffset, filterOne)) {\n              for (j = 0; j < groupIndex[k].length; j++) {\n                g = groups[groupIndex[k][j]];\n                g.value = reduceRemove(g.value, data[k], notFilter, j);\n              }\n            }\n          }\n          return;\n        }\n\n        // Add the added values.\n        for (i = 0, n = added.length; i < n; ++i) {\n          if (filters.zeroExcept(k = added[i], offset, zero)) {\n            g = groups[groupIndex[k]];\n            g.value = reduceAdd(g.value, data[k], false);\n          }\n        }\n\n        // Remove the removed values.\n        for (i = 0, n = removed.length; i < n; ++i) {\n          if (filters.onlyExcept(k = removed[i], offset, zero, filterOffset, filterOne)) {\n            g = groups[groupIndex[k]];\n            g.value = reduceRemove(g.value, data[k], notFilter);\n          }\n        }\n      }\n\n      // Reduces the specified selected or deselected records.\n      // This function is only used when the cardinality is 1.\n      // notFilter indicates a crossfilter.add/remove operation.\n      function updateOne(filterOne, filterOffset, added, removed, notFilter) {\n        if ((filterOne === one && filterOffset === offset) || resetNeeded) return;\n\n        var i,\n            k,\n            n,\n            g = groups[0];\n\n        // Add the added values.\n        for (i = 0, n = added.length; i < n; ++i) {\n          if (filters.zeroExcept(k = added[i], offset, zero)) {\n            g.value = reduceAdd(g.value, data[k], false);\n          }\n        }\n\n        // Remove the removed values.\n        for (i = 0, n = removed.length; i < n; ++i) {\n          if (filters.onlyExcept(k = removed[i], offset, zero, filterOffset, filterOne)) {\n            g.value = reduceRemove(g.value, data[k], notFilter);\n          }\n        }\n      }\n\n      // Recomputes the group reduce values from scratch.\n      // This function is only used when the cardinality is greater than 1.\n      function resetMany() {\n        var i,\n            j,\n            g;\n\n        // Reset all group values.\n        for (i = 0; i < k; ++i) {\n          groups[i].value = reduceInitial();\n        }\n\n        // We add all records and then remove filtered records so that reducers\n        // can build an 'unfiltered' view even if there are already filters in\n        // place on other dimensions.\n        if(iterable){\n          for (i = 0; i < n; ++i) {\n            for (j = 0; j < groupIndex[i].length; j++) {\n              g = groups[groupIndex[i][j]];\n              g.value = reduceAdd(g.value, data[i], true, j);\n            }\n          }\n          for (i = 0; i < n; ++i) {\n            if (!filters.zeroExcept(i, offset, zero)) {\n              for (j = 0; j < groupIndex[i].length; j++) {\n                g = groups[groupIndex[i][j]];\n                g.value = reduceRemove(g.value, data[i], false, j);\n              }\n            }\n          }\n          return;\n        }\n\n        for (i = 0; i < n; ++i) {\n          g = groups[groupIndex[i]];\n          g.value = reduceAdd(g.value, data[i], true);\n        }\n        for (i = 0; i < n; ++i) {\n          if (!filters.zeroExcept(i, offset, zero)) {\n            g = groups[groupIndex[i]];\n            g.value = reduceRemove(g.value, data[i], false);\n          }\n        }\n      }\n\n      // Recomputes the group reduce values from scratch.\n      // This function is only used when the cardinality is 1.\n      function resetOne() {\n        var i,\n            g = groups[0];\n\n        // Reset the singleton group values.\n        g.value = reduceInitial();\n\n        // We add all records and then remove filtered records so that reducers\n        // can build an 'unfiltered' view even if there are already filters in\n        // place on other dimensions.\n        for (i = 0; i < n; ++i) {\n          g.value = reduceAdd(g.value, data[i], true);\n        }\n\n        for (i = 0; i < n; ++i) {\n          if (!filters.zeroExcept(i, offset, zero)) {\n            g.value = reduceRemove(g.value, data[i], false);\n          }\n        }\n      }\n\n      // Returns the array of group values, in the dimension's natural order.\n      function all() {\n        if (resetNeeded) reset(), resetNeeded = false;\n        return groups;\n      }\n\n      // Returns a new array containing the top K group values, in reduce order.\n      function top(k) {\n        var top = select(all(), 0, groups.length, k);\n        return heap.sort(top, 0, top.length);\n      }\n\n      // Sets the reduce behavior for this group to use the specified functions.\n      // This method lazily recomputes the reduce values, waiting until needed.\n      function reduce(add, remove, initial) {\n        reduceAdd = add;\n        reduceRemove = remove;\n        reduceInitial = initial;\n        resetNeeded = true;\n        return group;\n      }\n\n      // A convenience method for reducing by count.\n      function reduceCount() {\n        return reduce(xfilterReduce.reduceIncrement, xfilterReduce.reduceDecrement, cr_zero);\n      }\n\n      // A convenience method for reducing by sum(value).\n      function reduceSum(value) {\n        return reduce(xfilterReduce.reduceAdd(value), xfilterReduce.reduceSubtract(value), cr_zero);\n      }\n\n      // Sets the reduce order, using the specified accessor.\n      function order(value) {\n        select = xfilterHeapselect.by(valueOf);\n        heap = xfilterHeap.by(valueOf);\n        function valueOf(d) { return value(d.value); }\n        return group;\n      }\n\n      // A convenience method for natural ordering by reduce value.\n      function orderNatural() {\n        return order(cr_identity);\n      }\n\n      // Returns the cardinality of this group, irrespective of any filters.\n      function size() {\n        return k;\n      }\n\n      // Removes this group and associated event listeners.\n      function dispose() {\n        var i = filterListeners.indexOf(update);\n        if (i >= 0) filterListeners.splice(i, 1);\n        i = indexListeners.indexOf(add);\n        if (i >= 0) indexListeners.splice(i, 1);\n        i = removeDataListeners.indexOf(removeData);\n        if (i >= 0) removeDataListeners.splice(i, 1);\n        i = dimensionGroups.indexOf(group);\n        if (i >= 0) dimensionGroups.splice(i, 1);\n        return group;\n      }\n\n      return reduceCount().orderNatural();\n    }\n\n    // A convenience function for generating a singleton group.\n    function groupAll() {\n      var g = group(cr_null), all = g.all;\n      delete g.all;\n      delete g.top;\n      delete g.order;\n      delete g.orderNatural;\n      delete g.size;\n      g.value = function() { return all()[0].value; };\n      return g;\n    }\n\n    // Removes this dimension and associated groups and event listeners.\n    function dispose() {\n      dimensionGroups.forEach(function(group) { group.dispose(); });\n      var i = dataListeners.indexOf(preAdd);\n      if (i >= 0) dataListeners.splice(i, 1);\n      i = dataListeners.indexOf(postAdd);\n      if (i >= 0) dataListeners.splice(i, 1);\n      i = removeDataListeners.indexOf(removeData);\n      if (i >= 0) removeDataListeners.splice(i, 1);\n      filters.masks[offset] &= zero;\n      return filterAll();\n    }\n\n    return dimension;\n  }\n\n  // A convenience method for groupAll on a dummy dimension.\n  // This implementation can be optimized since it always has cardinality 1.\n  function groupAll() {\n    var group = {\n      reduce: reduce,\n      reduceCount: reduceCount,\n      reduceSum: reduceSum,\n      value: value,\n      dispose: dispose,\n      remove: dispose // for backwards-compatibility\n    };\n\n    var reduceValue,\n        reduceAdd,\n        reduceRemove,\n        reduceInitial,\n        resetNeeded = true;\n\n    // The group listens to the crossfilter for when any dimension changes, so\n    // that it can update the reduce value. It must also listen to the parent\n    // dimension for when data is added.\n    filterListeners.push(update);\n    dataListeners.push(add);\n\n    // For consistency; actually a no-op since resetNeeded is true.\n    add(data, 0, n);\n\n    // Incorporates the specified new values into this group.\n    function add(newData, n0) {\n      var i;\n\n      if (resetNeeded) return;\n\n      // Cycle through all the values.\n      for (i = n0; i < n; ++i) {\n\n        // Add all values all the time.\n        reduceValue = reduceAdd(reduceValue, data[i], true);\n\n        // Remove the value if filtered.\n        if (!filters.zero(i)) {\n          reduceValue = reduceRemove(reduceValue, data[i], false);\n        }\n      }\n    }\n\n    // Reduces the specified selected or deselected records.\n    function update(filterOne, filterOffset, added, removed, notFilter) {\n      var i,\n          k,\n          n;\n\n      if (resetNeeded) return;\n\n      // Add the added values.\n      for (i = 0, n = added.length; i < n; ++i) {\n        if (filters.zero(k = added[i])) {\n          reduceValue = reduceAdd(reduceValue, data[k], notFilter);\n        }\n      }\n\n      // Remove the removed values.\n      for (i = 0, n = removed.length; i < n; ++i) {\n        if (filters.only(k = removed[i], filterOffset, filterOne)) {\n          reduceValue = reduceRemove(reduceValue, data[k], notFilter);\n        }\n      }\n    }\n\n    // Recomputes the group reduce value from scratch.\n    function reset() {\n      var i;\n\n      reduceValue = reduceInitial();\n\n      // Cycle through all the values.\n      for (i = 0; i < n; ++i) {\n\n        // Add all values all the time.\n        reduceValue = reduceAdd(reduceValue, data[i], true);\n\n        // Remove the value if it is filtered.\n        if (!filters.zero(i)) {\n          reduceValue = reduceRemove(reduceValue, data[i], false);\n        }\n      }\n    }\n\n    // Sets the reduce behavior for this group to use the specified functions.\n    // This method lazily recomputes the reduce value, waiting until needed.\n    function reduce(add, remove, initial) {\n      reduceAdd = add;\n      reduceRemove = remove;\n      reduceInitial = initial;\n      resetNeeded = true;\n      return group;\n    }\n\n    // A convenience method for reducing by count.\n    function reduceCount() {\n      return reduce(xfilterReduce.reduceIncrement, xfilterReduce.reduceDecrement, cr_zero);\n    }\n\n    // A convenience method for reducing by sum(value).\n    function reduceSum(value) {\n      return reduce(xfilterReduce.reduceAdd(value), xfilterReduce.reduceSubtract(value), cr_zero);\n    }\n\n    // Returns the computed reduce value.\n    function value() {\n      if (resetNeeded) reset(), resetNeeded = false;\n      return reduceValue;\n    }\n\n    // Removes this group and associated event listeners.\n    function dispose() {\n      var i = filterListeners.indexOf(update);\n      if (i >= 0) filterListeners.splice(i, 1);\n      i = dataListeners.indexOf(add);\n      if (i >= 0) dataListeners.splice(i, 1);\n      return group;\n    }\n\n    return reduceCount();\n  }\n\n  // Returns the number of records in this crossfilter, irrespective of any filters.\n  function size() {\n    return n;\n  }\n\n  // Returns the raw row data contained in this crossfilter\n  function all(){\n    return data;\n  }\n\n  // Returns row data with all dimension filters applied, except for filters in ignore_dimensions\n  function allFiltered(ignore_dimensions) {\n    var array = [],\n        i = 0,\n        mask = maskForDimensions(ignore_dimensions || []);\n\n      for (i = 0; i < n; i++) {\n        if (filters.zeroExceptMask(i, mask)) {\n          array.push(data[i]);\n        }\n      }\n\n      return array;\n  }\n\n  function onChange(cb){\n    if(typeof cb !== 'function'){\n      /* eslint no-console: 0 */\n      console.warn('onChange callback parameter must be a function!');\n      return;\n    }\n    callbacks.push(cb);\n    return function(){\n      callbacks.splice(callbacks.indexOf(cb), 1);\n    };\n  }\n\n  function triggerOnChange(eventName){\n    for (var i = 0; i < callbacks.length; i++) {\n      callbacks[i](eventName);\n    }\n  }\n\n  return arguments.length\n      ? add(arguments[0])\n      : crossfilter;\n}\n\n// Returns an array of size n, big enough to store ids up to m.\nfunction cr_index(n, m) {\n  return (m < 0x101\n      ? xfilterArray.array8 : m < 0x10001\n      ? xfilterArray.array16\n      : xfilterArray.array32)(n);\n}\n\n// Constructs a new array of size n, with sequential values from 0 to n - 1.\nfunction cr_range(n) {\n  var range = cr_index(n, n);\n  for (var i = -1; ++i < n;) range[i] = i;\n  return range;\n}\n\nfunction capacity(w) {\n  return w === 8\n      ? 0x100 : w === 16\n      ? 0x10000\n      : 0x100000000;\n}\n","import {d3} from './lib';\nimport crossfilter from 'crossfilter2';\n\n/* Decompresses ideogram's annotations for crossfilter initialization\nBy default, annotations are clustered by chromosome, e.g.\n[\n  {\"chr\": \"1\", \"annots\": [{\"from\": 100, \"to\", 101, \"chr\": \"1\", ...}, ...]},\n  {\"chr\": \"2\", \"annots\": [{\"from\": 500, \"to\", 501, \"chr\": \"2\", ...}, ...]},\n  ...\n]\nThis method flattens that structure to e.g.\n[\n  {\"from\": 100, \"to\": 101, \"chr\": \"1\", ...},\n  ...\n  {\"from\": 500, \"to\": 501, \"chr\": \"2\", ...},\n]\nSee also: packAnnots\n*/\nfunction unpackAnnots() {\n  var chr, annots, i,\n    unpackedAnnots = [],\n    ideo = this,\n    chrs = ideo.annots;\n\n  for (i = 0; i < chrs.length; i++) {\n    chr = chrs[i];\n    annots = chr.annots;\n    unpackedAnnots = unpackedAnnots.concat(annots);\n  }\n\n  return unpackedAnnots;\n}\n\n/*\n  Compresses annots back to default state.  Inverse of unpackAnnots.\n*/\nfunction packAnnots(unpackedAnnots) {\n  var chr, annot, i,\n    annots = [],\n    ideo = this,\n    chrs = ideo.annots;\n\n  for (chr in chrs) {\n    annots.push({chr: chrs[chr].chr, annots: []});\n  }\n\n  for (i = 0; i < unpackedAnnots.length; i++) {\n    annot = unpackedAnnots[i];\n    annots[annot.chrIndex].annots.push(annot);\n  }\n\n  return annots;\n}\n\n/*\n  Initializes crossfilter.  Needed for client-side filtering.\n  More: https://github.com/square/crossfilter/wiki/API-Reference\n*/\nfunction initCrossFilter() {\n  var i, facet,\n    ideo = this,\n    keys = ideo.rawAnnots.keys;\n\n  ideo.unpackedAnnots = ideo.unpackAnnots();\n  ideo.crossfilter = crossfilter(ideo.unpackedAnnots);\n\n  ideo.annotsByFacet = {};\n  ideo.facets = keys.slice(3, keys.length);\n\n  for (i = 0; i < ideo.facets.length; i++) {\n    facet = ideo.facets[i];\n    ideo.annotsByFacet[facet] =\n      ideo.crossfilter.dimension(function(d) {\n        return d[facet];\n      });\n  }\n\n  if ('filterSelections' in ideo) {\n    ideo.filterAnnots(ideo.filterSelections);\n  }\n\n  ideo.filteredAnnots = ideo.annots;\n}\n\nfunction getFilteredResults(selections, ideo) {\n  var fn, i, facet, results, filter,\n    counts = {};\n\n  if (Object.keys(selections).length === 0) {\n    results = ideo.unpackedAnnots;\n  } else {\n    for (i = 0; i < ideo.facets.length; i++) {\n      facet = ideo.facets[i];\n      if (facet in selections) {\n        filter = selections[facet];\n        if (Array.isArray(filter)) {\n          fn = function(d) {\n            // Filter is numeric range\n            if (filter.length === 2) {\n              // [min, max]\n              return filter[0] <= d && d < filter[1];\n            } else if (filter.length === 4) {\n              // [min1, max1, min2, max2]\n              return (\n                filter[0] <= d && d < filter[1] ||\n                filter[2] <= d && d < filter[3]\n              );\n            }\n          };\n        } else {\n          fn = function(d) {\n            // Filter is set of categories\n            return (d in filter);\n          };\n        }\n      } else {\n        fn = null;\n      }\n      ideo.annotsByFacet[facet].filter(fn);\n      counts[facet] = ideo.annotsByFacet[facet].group().top(Infinity);\n    }\n    results = ideo.annotsByFacet[facet].top(Infinity);\n  }\n\n  return [results, counts];\n}\n\n/*\n  Filters annotations based on the given selections.\n  \"selections\" is an object of objects, e.g.\n\n    {\n      \"tissue-type\": {          <-- a facet\n        \"cerebral-cortex\": 1,   <-- a filter; \"1\" means it is selected\n        \"liver\": 1\n      },\n      \"gene-type\": {\n        mirna\": 1\n      }\n    }\n\n  Translation:\n  select where:\n      (tissue-type is cerebral-cortex OR liver) and (gene-type is mirna)\n\n  TODO:\n    * Filter counts\n    * Integrate server-side filtering for very large datasets\n*/\nfunction filterAnnots(selections) {\n  var i, facet, results, counts,\n    t0 = Date.now(),\n    ideo = this;\n\n  ideo.filterSelections = selections;\n  [results, counts] = getFilteredResults(selections, ideo);\n\n  for (i < 0; i < ideo.facets.length; i++) {\n    ideo.annotsByFacet[facet].filterAll(); // clear filters\n  }\n\n  results = ideo.packAnnots(results);\n\n  delete ideo.maxAnnotsPerBar;\n  delete ideo.maxAnnotsPerBarAllChrs;\n\n  ideo.filteredAnnots = results;\n\n  d3.selectAll(ideo.selector + ' polygon.annot').remove();\n  ideo.drawAnnots(results);\n\n  console.log('Time in filterAnnots: ' + (Date.now() - t0) + ' ms');\n\n  return counts;\n}\n\nexport {unpackAnnots, packAnnots, initCrossFilter, filterAnnots};\n","function getPixelAndOtherData(bands, chr, hasBands, ideo) {\n  var i, band, csLength, width, maxLength,\n    pxStop = 0,\n    taxid = chr.id.split('-')[1],\n    cs = ideo.coordinateSystem,\n    chrHeight = ideo.config.chrHeight;\n\n  for (i = 0; i < bands.length; i++) {\n    band = bands[i];\n    csLength = band[cs].stop - band[cs].start;\n\n    // If ideogram is rotated (and thus showing only one chromosome),\n    // then set its width independent of the longest chromosome in this\n    // genome.\n    if (ideo._layout._isRotated) {\n      width = chrHeight * csLength / chr.length;\n    } else {\n      if (ideo.config.chromosomeScale === 'relative') {\n        maxLength = ideo.maxLength[taxid][cs];\n      } else {\n        maxLength = ideo.maxLength[cs];\n      }\n      width = chrHeight * chr.length / maxLength * csLength / chr.length;\n    }\n    bands[i].px = {start: pxStop, stop: pxStop + width, width: width};\n\n    pxStop = bands[i].px.stop;\n\n    if (hasBands && band.stain === 'acen' && band.name[0] === 'p') {\n      chr.pcenIndex = i;\n    }\n  }\n  return [bands, chr, pxStop];\n}\n\n/**\n * TODO:\n * A chromosome-level scale property is likely\n * nonsensical for any chromosomes that have cytogenetic band data.\n * Different bands tend to have ratios between number of base pairs\n * and physical length.\n *\n * However, a chromosome-level scale property is likely\n * necessary for chromosomes that do not have band data.\n *\n * This needs further review.\n */\nfunction getChrScale(chr, hasBands, ideo) {\n  var chrHeight = ideo.config.chrHeight,\n    chrLength = chr.length,\n    maxLength = ideo.maxLength,\n    taxid = chr.id.split('-')[1],\n    scale = {};\n\n  scale.bp = chrHeight / maxLength.bp;\n\n  if (ideo.config.multiorganism === true) {\n    // chr.scale.bp = band.iscn.stop / band.bp.stop;\n    if (ideo.config.chromosomeScale === 'relative') {\n      scale.iscn = chrHeight * chrLength / maxLength[taxid].bp;\n      scale.bp = chrHeight / maxLength[taxid].bp;\n    } else {\n      scale.iscn = chrHeight * chrLength / maxLength.bp;\n    }\n  } else if (hasBands) {\n    scale.iscn = chrHeight / maxLength.iscn;\n  }\n\n  return scale;\n}\n\nfunction getChromosomePixels(chr) {\n  var bands, chrHeight, pxStop, hasBands, maxLength,\n    taxid = chr.id.split('-')[1],\n    ideo = this;\n\n  bands = chr.bands;\n  chrHeight = ideo.config.chrHeight;\n  pxStop = 0;\n  hasBands = (typeof bands !== 'undefined');\n\n  if (hasBands) {\n    [bands, chr, pxStop] = getPixelAndOtherData(bands, chr, hasBands, ideo);\n  } else {\n    if (ideo.config.chromosomeScale === 'relative') {\n      maxLength = ideo.maxLength[taxid][ideo.coordinateSystem];\n    } else {\n      maxLength = ideo.maxLength[ideo.coordinateSystem];\n    }\n    pxStop = chrHeight * chr.length / maxLength;\n  }\n\n  chr.width = pxStop;\n  chr.scale = getChrScale(chr, hasBands, ideo);\n  chr.bands = bands;\n\n  return chr;\n}\n\nfunction getChrModelScaffold(chr, bands, chrName, ideo) {\n  var hasBands = (typeof bands !== 'undefined');\n\n  if (hasBands) {\n    chr.name = chrName;\n    chr.length = bands[bands.length - 1][ideo.coordinateSystem].stop;\n    chr.type = 'nuclear';\n  } else {\n    chr = chrName;\n  }\n\n  return chr;\n}\n\n/**\n * Encountered when processing an assembly that has chromosomes with\n * centromere data, but this chromosome does not.\n * Example: chromosome F1 in Felis catus.\n */\nfunction deleteExtraneousBands(chr, hasBands) {\n  if (hasBands && chr.bands.length === 1) {\n    delete chr.bands;\n  }\n  return chr;\n}\n\nfunction getCentromerePosition(hasBands, bands) {\n\n  const hasTelocentricPArm = (\n    // As with almost all mouse chromosome, chimpanzee chr22\n    hasBands && bands[0].name[0] === 'p' && bands[1].name[0] === 'q' &&\n    bands[0].bp.stop - bands[0].bp.start < 2E6\n  );\n\n  let hasTelocentricQArm = false;\n  if (hasBands) {\n    // As with Macaca mulatta chromosome Y\n    const lastBand = bands.slice(-1)[0];\n    const penultimateBand = bands.slice(-2)[0];\n\n    hasTelocentricQArm = (\n      hasBands && penultimateBand.name[0] === 'p' && lastBand.name[0] === 'q' &&\n      lastBand.bp.stop - lastBand.bp.start < 2E6\n    );\n  }\n\n  if (hasTelocentricPArm) {\n    // As with almost all mouse chromosome, chimpanzee chr22\n    return 'telocentric-p';\n  } else if (hasTelocentricQArm) {\n    return 'telocentric-q';\n  } else {\n    return '';\n  }\n}\n\n/**\n * Generates a model object for each chromosome containing information on\n * its name, DOM ID, length in base pairs or ISCN coordinates, cytogenetic\n * bands, centromere position, etc.\n */\nfunction getChromosomeModel(bands, chrName, taxid, chrIndex) {\n  var hasBands, org,\n    chr = {},\n    ideo = this;\n\n  hasBands = (typeof bands !== 'undefined');\n\n  chr = getChrModelScaffold(chr, bands, chrName, ideo);\n\n  chr.chrIndex = chrIndex;\n  chr.id = 'chr' + chr.name + '-' + taxid;\n\n  if (ideo.config.fullChromosomeLabels === true) {\n    org = this.organisms[taxid];\n    chr.name = org.scientificName + ' chr' + chr.name;\n  }\n\n  chr.bands = bands;\n  chr = ideo.getChromosomePixels(chr);\n  chr.centromerePosition = getCentromerePosition(hasBands, bands);\n\n  chr = deleteExtraneousBands(chr, hasBands);\n\n  return chr;\n}\n\nexport {getChromosomeModel, getChromosomePixels};\n","/* eslint-disable no-use-before-define */\n\nexport class ModelAdapter {\n\n  constructor(model) {\n    this._model = model;\n    this._class = 'ModelAdapter';\n  }\n\n  static getInstance(model) {\n    if (model.bands) {\n      return new ModelAdapter(model);\n    } else {\n      return new ModelNoBandsAdapter(model);\n    }\n  }\n\n  getModel() {\n    return this._model;\n  }\n\n  getCssClass() {\n    return '';\n  }\n}\n\nexport class ModelNoBandsAdapter extends ModelAdapter {\n\n  constructor(model) {\n    super(model);\n    this._class = 'ModelNoBandsAdapter';\n  }\n\n  getModel() {\n    this._model.bands = [];\n\n    // If chromosome width more than 1, add single band to bands array\n    if (this._model.width > 1) {\n      this._model.bands.push({\n        name: 'q',\n        px: {\n          start: 0,\n          stop: this._model.width,\n          width: this._model.width\n        },\n        bp: {\n          start: 1,\n          stop: this._model.length\n        }\n      });\n    }\n\n    return this._model;\n  }\n\n  getCssClass() {\n    return 'noBands';\n  }\n\n}\n","import {Ploidy} from './ploidy';\n\nexport class Color {\n\n  constructor(config) {\n    // Ideogram config\n    this._config = config;\n    this._ploidy = new Ploidy(this._config);\n  }\n\n  getArmColor(chrSetIndex, chrIndex, armIndex) {\n    if (this._config.armColors) {\n      return this._config.armColors[armIndex];\n    } else if (this._config.ancestors) {\n      return this._getPolyploidArmColor(chrSetIndex, chrIndex, armIndex);\n    } else {\n      return null;\n    }\n  }\n\n  getBorderColor(chrSetIndex, chrIndex, armIndex) {\n    if (chrIndex < this._config.ploidy) {\n      return '#000';\n    } else if (this._ploidy.exists(chrSetIndex, chrIndex, armIndex)) {\n      return '#000';\n    } else {\n      return '#fff';\n    }\n  }\n\n  _getPolyploidArmColor(chrSetIndex, chrIndex, armIndex) {\n    if (!this._ploidy.exists(chrSetIndex, chrIndex, armIndex)) {\n      return 'transparent';\n    } else {\n      var ancestor =\n        this._ploidy.getAncestor(chrSetIndex, chrIndex, armIndex);\n      return this._config.ancestors[ancestor];\n    }\n  }\n\n}\n","export class Range {\n\n  /**\n  * Chromosome range.\n  * @public\n  * @class\n  * @param {Object} data - range data.\n  * @param {Integer} data.chr - chromosome index.\n  * @param {Integer[]} [data.ploidy] - array which controls on which\n  *                                    chromosomes range should appear in case\n  *                                    of ploidy.\n  * @param {Integer} data.start - range start.\n  * @param {Integer} data.stop - range end.\n  * @param {String} data.color - range color.\n  */\n  constructor(data) {\n    this._data = data;\n    this.start = data.start;\n    this.stop = data.stop;\n    this.length = this.stop - this.start;\n  }\n\n  getColor(chrIndex) {\n    if (!('ploidy' in this._data)) {\n      return this._getColor(chrIndex);\n    } else if ('ploidy' in this._data && this._data.ploidy[chrIndex]) {\n      return this._getColor(chrIndex);\n    } else {\n      return 'transparent';\n    }\n  }\n\n  _getColor(chrIndex) {\n    if (Array.isArray(this._data.color)) {\n      return this._data.color[chrIndex];\n    } else {\n      return this._data.color;\n    }\n  }\n\n}\n","/* eslint-disable no-use-before-define */\nimport {Color} from './../color';\nimport {Range} from './../range';\n\nexport class Chromosome {\n\n  constructor(adapter, config, ideo) {\n    this._adapter = adapter;\n    this._model = this._adapter.getModel();\n    this._config = config;\n    this._ideo = ideo;\n    this._color = new Color(this._config);\n    this._bumpCoefficient = 5;\n  }\n\n  /**\n   * Factory method\n   */\n  static getInstance(adapter, config, ideo) {\n    const centromerePosition = adapter.getModel().centromerePosition;\n    if (centromerePosition === 'telocentric-p') {\n      return new TelocentricPChromosome(adapter, config, ideo);\n    } else if (centromerePosition === 'telocentric-q') {\n      return new TelocentricQChromosome(adapter, config, ideo);\n    } else {\n      return new MetacentricChromosome(adapter, config, ideo);\n    }\n  }\n\n  _addPArmShape(clipPath, isPArmRendered) {\n    if (isPArmRendered) {\n      return clipPath.concat(this._getPArmShape());\n    } else {\n      return clipPath;\n    }\n  }\n\n  _addQArmShape(clipPath, isQArmRendered) {\n    if (isQArmRendered) {\n      return clipPath.concat(this._getQArmShape());\n    } else {\n      return clipPath;\n    }\n  }\n\n  /**\n   * Append bands container and apply clip-path to it\n   */\n  render(container, chrSetIndex, chrIndex) {\n\n    var self, isPArmRendered, isQArmRendered, clipPath, opacity, fill,\n      isFullyBanded;\n\n    self = this;\n\n    container = container.append('g')\n      .attr('class', 'bands')\n      .attr('clip-path',\n        'url(#' + this._model.id + '-chromosome-set-clippath)'\n      );\n\n    // Render chromosome arms\n    isPArmRendered = this._renderArm(container, chrSetIndex, chrIndex, 'p');\n    isQArmRendered = this._renderArm(container, chrSetIndex, chrIndex, 'q');\n\n    // Render range set\n    this._renderRangeSet(container, chrSetIndex, chrIndex);\n\n    // Push arms shape string into clipPath array\n    clipPath = [];\n    clipPath = this._addPArmShape(clipPath, isPArmRendered);\n    clipPath = this._addQArmShape(clipPath, isQArmRendered);\n\n    opacity = '0';\n    fill = '';\n    isFullyBanded = this.isFullyBanded();\n    if (\n      'ancestors' in this._ideo.config &&\n      !('rangeSet' in this._ideo.config)\n    ) {\n      // E.g. diploid human genome (with translucent overlay)\n      fill = self._color.getArmColor(chrSetIndex, chrIndex, 0);\n      if (isFullyBanded) {\n        opacity = '0.5';\n      }\n    } else if (isFullyBanded) {\n      // E.g. mouse reference genome\n      opacity = null;\n      fill = 'transparent';\n    } else if (!('ancestors' in this._ideo.config)) {\n      // E.g. chimpanzee assembly Pan_tro 3.0\n      opacity = '1';\n    }\n\n    // Render chromosome border\n    container.append('g')\n      .attr('class', 'chromosome-border')\n      .selectAll('path')\n      .data(clipPath)\n      .enter()\n      .append('path')\n      .attr('fill', fill)\n      .style('fill-opacity', opacity)\n      .attr('stroke', function(d, i) {\n        return self._color.getBorderColor(chrSetIndex, chrIndex, i);\n      })\n      .attr('stroke-width', function(d) {\n        return ('strokeWidth' in d ? d.strokeWidth : 1);\n      })\n      .attr('d', function(d) {\n        return d.path;\n      }).attr('class', function(d) {\n        return d.class;\n      });\n\n    return clipPath;\n  }\n\n  _renderRangeSet(container, chrSetIndex, chrIndex) {\n\n    var self, rangeSet, rangesContainer, ideo;\n\n    if (!('rangeSet' in this._config)) {\n      return;\n    }\n\n    rangeSet = this._config.rangeSet.filter(function(range) {\n      return range.chr - 1 === chrSetIndex;\n    }).map(function(range) {\n      return new Range(range);\n    });\n\n    rangesContainer = container.append('g').attr('class', 'range-set');\n\n    self = this;\n    ideo = self._ideo;\n\n    rangesContainer.selectAll('rect.range')\n      .data(rangeSet)\n      .enter()\n      .append('rect')\n      .attr('class', 'range')\n      .attr('x', function(range) {\n        return ideo.convertBpToPx(self._model, range.start);\n      }).attr('y', 0)\n      .attr('width', function(range) {\n        return ideo.convertBpToPx(self._model, range.length);\n      }).attr('height', this._config.chrWidth)\n      .style('fill', function(range) {\n        return range.getColor(chrIndex);\n      });\n  }\n\n  /**\n   * Get chromosome's shape main values\n   */\n  _getShapeData() {\n\n    var firstQBand, i, lastBand, rightTerminalPosition;\n\n    // First q band from bands sequence\n    for (i = 0; i < this._model.bands.length; i++) {\n      if (this._model.bands[i].name[0] === 'q') {\n        firstQBand = this._model.bands[i];\n        break;\n      }\n    }\n\n    // Chromosome's right position\n    lastBand = this._model.bands.length - 1;\n    rightTerminalPosition = this._model.bands[lastBand].px.stop;\n\n    // Properties description:\n    // x1 - left terminal start position\n    // x2 - centromere position\n    // x3 - right terminal end position\n    // w - chromosome width\n    // b - bump size\n    return {\n      x1: 0,\n      x2: firstQBand ? firstQBand.px.start : rightTerminalPosition,\n      x3: rightTerminalPosition,\n      w: this._config.chrWidth,\n      b: this._config.chrWidth / this._bumpCoefficient\n    };\n  }\n\n  _getPArmShape() {\n    var d = this._getShapeData(),\n      x = d.x2 - d.b;\n\n    if (this.isFullyBanded() || 'ancestors' in this._ideo.config) {\n      // Encountered when chromosome has any of:\n      //  - One placeholder \"band\", e.g. pig genome GCF_000003025.5\n      //  - Many (> 2) bands, e.g. human reference genome\n      //  - Ancestor colors in ploidy configuration, as in ploidy-basic.html\n      return {\n        class: '',\n        path:\n          'M' + d.b + ',0 ' +\n          'L' + x + ',0 ' +\n          'Q' + (d.x2 + d.b) + ',' + (d.w / 2) + ',' + x + ',' + d.w + ' ' +\n          'L' + d.b + ',' + d.w + ' ' +\n          'Q-' + d.b + ',' + (d.w / 2) + ',' + d.b + ',0'\n      };\n    } else {\n      // e.g. chimpanzee assembly Pan_tro 3.0\n      return [{\n        class: '',\n        path:\n          'M' + d.b + ',0 ' +\n          'L' + (x - 2) + ',0 ' +\n          'L' + (x - 2) + ',' + d.w + ' ' +\n          'L' + d.b + ',' + d.w + ' ' +\n          'Q-' + d.b + ',' + (d.w / 2) + ',' + d.b + ',0'\n      }, {\n        class: 'acen',\n        path:\n          'M' + x + ',0 ' +\n          'Q' + (d.x2 + d.b) + ',' + (d.w / 2) + ',' + x + ',' + d.w + ' ' +\n          'L' + x + ',' + d.w + ' ' +\n          'L' + (x - 2) + ',' + d.w + ' ' +\n          'L' + (x - 2) + ',0'\n      }];\n    }\n  }\n\n  _getQArmShape() {\n    var d = this._getShapeData(),\n      x = d.x3 - d.b,\n      x2b = d.x2 + d.b;\n\n    if (this.isFullyBanded() || 'ancestors' in this._ideo.config) {\n      return {\n        class: '',\n        path:\n          'M' + x2b + ',0 ' +\n          'L' + x + ',0 ' +\n          'Q' + (d.x3 + d.b) + ',' + (d.w / 2) + ',' + x + ',' + d.w + ' ' +\n          'L' + x2b + ',' + d.w + ' ' +\n          'Q' + (d.x2 - d.b) + ',' + (d.w / 2) + ',' + x2b + ',0'\n      };\n    } else {\n      // e.g. chimpanzee assembly Pan_tro 3.0\n      return [{\n        path:\n          'M' + x2b + ',0 ' +\n          'L' + x + ',0 ' +\n          'Q' + (d.x3 + d.b) + ',' + (d.w / 2) + ',' + x + ',' + d.w + ' ' +\n          'L' + x2b + ',' + d.w + ' ' +\n          'L' + x2b + ',0'\n      }, {\n        class: 'acen',\n        path:\n          'M' + x2b + ',0' +\n          'Q' + (d.x2 - d.b) + ',' + (d.w / 2) + ',' + x2b + ',' + d.w + ' ' +\n          'L' + x2b + ',' + d.w +\n          'L' + (x2b + 2) + ',' + d.w +\n          'L' + (x2b + 2) + ',0'\n      }];\n    }\n  }\n\n  isFullyBanded() {\n    return (\n      this._model.bands &&\n      (this._model.bands.length !== 2 || this._model.bands[0].name[0] === 'q')\n    );\n  }\n\n  /**\n   * Render arm bands\n   */\n  _renderBands(container, chrSetIndex, chrIndex, bands, arm) {\n\n    var self, armIndex, fill;\n\n    self = this;\n    armIndex = arm === 'p' ? 0 : 1;\n    fill = '';\n\n    if ('ancestors' in self._ideo.config && !(self.isFullyBanded())) {\n      fill = self._color.getArmColor(chrSetIndex, chrIndex, armIndex);\n    }\n\n    container.selectAll('path.band.' + arm)\n      .data(bands)\n      .enter()\n      .append('path')\n      .attr('id', function(d) {\n        return self._model.id + '-' + d.name.replace('.', '-');\n      })\n      .attr('class', function(d) {\n        return 'band ' + arm + '-band ' + d.stain;\n      })\n      .attr('d', function(d) {\n        var start, length;\n\n        start = self._ideo.round(d.px.start);\n        length = self._ideo.round(d.px.width);\n\n        return 'M ' + start + ', 0' +\n              'l ' + length + ' 0 ' +\n              'l 0 ' + self._config.chrWidth + ' ' +\n              'l -' + length + ' 0 z';\n      })\n      .style('fill', fill);\n  }\n\n  /**\n   * Render a chromosome arm.\n   * Returns boolean indicating if any bands were rendered.\n   */\n  _renderArm(container, chrSetIndex, chrIndex, arm) {\n    var bands = this._model.bands.filter(function(band) {\n      return band.name[0] === arm;\n    });\n\n    this._renderBands(container, chrSetIndex, chrIndex, bands, arm);\n\n    return Boolean(bands.length);\n  }\n}\n\nexport class MetacentricChromosome extends Chromosome {\n\n  constructor(model, config, ideo) {\n    super(model, config, ideo);\n    this._class = 'MetacentricChromosome';\n  }\n}\n\nexport class TelocentricPChromosome extends Chromosome {\n\n  constructor(model, config, ideo) {\n    // alert('p')\n    super(model, config, ideo);\n    this._class = 'TelocentricPChromosome';\n    this._pArmOffset = 3;\n  }\n\n  _addPArmShape(clipPath) {\n    return clipPath.concat(this._getPArmShape());\n  }\n\n  _getPArmShape() {\n    // Properties description:\n    // x1 - left terminal start position\n    // x2 - centromere position\n    // x3 - right terminal end position\n    // w - chromosome width\n    // b - bump size\n    var d = this._getShapeData();\n    d.o = this._pArmOffset;\n\n    return [{\n      class: 'acen',\n      path: 'M' + (d.x2 + 2) + ',1' +\n      'L' + (d.x2 + d.o + 3.25) + ',1 ' +\n      'L' + (d.x2 + d.o + 3.25) + ',' + (d.w - 1) + ' ' +\n      'L' + (d.x2 + 2) + ',' + (d.w - 1)\n    }, {\n      class: 'gpos66',\n      path: 'M' + (d.x2 - d.o + 5) + ',0' +\n      'L' + (d.x2 - d.o + 3) + ',0 ' +\n      'L' + (d.x2 - d.o + 3) + ',' + d.w + ' ' +\n      'L' + (d.x2 - d.o + 5) + ',' + d.w,\n      strokeWidth: 0.5\n    }];\n  }\n\n  _getQArmShape() {\n    // Properties description:\n    // x1 - left terminal start position\n    // x2 - centromere position\n    // x3 - right terminal end position\n    // w - chromosome width\n    // b - bump size\n    var d = this._getShapeData(),\n      x = d.x3 - d.b,\n      o = this._pArmOffset + 3;\n\n    return {\n      class: '',\n      path:\n      'M' + (d.x2 + o) + ',0 ' +\n      'L' + x + ',0 ' +\n      'Q' + (d.x3 + d.b) + ',' + (d.w / 2) + ',' + x + ',' + d.w + ' ' +\n      'L' + (d.x2 + o) + ',' + d.w\n    };\n  }\n}\n\nexport class TelocentricQChromosome extends Chromosome {\n\n  constructor(model, config, ideo) {\n    // alert('q')\n    super(model, config, ideo);\n    this._class = 'TelocentricQChromosome';\n    this._qArmOffset = 3;\n  }\n\n  _getPArmShape() {\n    // Properties description:\n    // x1 - left terminal start position\n    // x2 - centromere position\n    // x3 - right terminal end position\n    // w - chromosome width\n    // b - bump size\n\n    var d = this._getShapeData(),\n      x = d.x3 - d.b,\n      o = this._qArmOffset;\n\n    return {\n      class: '',\n      path:\n      // 'M1,0, ' +\n      'M' + (d.x2 + o) + ',0 ' +\n      'L' + (x + o) + ',0 ' +\n      'L' + (x + o) + ',' + d.w + ' ' +\n      'L' + d.b + ',' + d.w + ' ' +\n      'Q-' + d.b + ',' + (d.w / 2) + ',' + d.b + ',0'\n    };\n  }\n\n  _addQArmShape(clipPath) {\n    return clipPath.concat(this._getQArmShape());\n  }\n\n  _getQArmShape() {\n    // Properties description:\n    // x1 - left terminal start position\n    // x2 - centromere position\n    // x3 - right terminal end position\n    // w - chromosome width\n    // b - bump size\n    var d = this._getShapeData();\n    d.o = this._qArmOffset;\n\n    return [{\n      class: 'acen',\n      path: 'M' + (d.x2 + 2) + ',1 ' +\n      'L' + (d.x2 + d.o + 3.25) + ',1 ' +\n      'L' + (d.x2 + d.o + 3.25) + ',' + (d.w - 1) + ' ' +\n      'L' + (d.x2 + 2) + ',' + (d.w - 1)\n    }, {\n      class: 'gpos66',\n      path: 'M' + (d.x2 + d.o + 5) + ',0 ' +\n      'L' + (d.x2 + d.o + 3) + ',0 ' +\n      'L' + (d.x2 + d.o + 3) + ',' + d.w + ' ' +\n      'L' + (d.x2 + d.o + 5) + ',' + d.w,\n      strokeWidth: 0.5\n    }];\n  }\n}\n","import {d3} from '../lib';\n// import {initSettings} from '../init/settings-ui';\nimport {ModelAdapter} from '../model-adapter';\nimport {Chromosome} from './chromosome';\n\n/**\n * Adds a copy of a chromosome (i.e. a homologous chromosome, homolog) to DOM\n *\n * @param chrModel\n * @param chrIndex\n * @param homologIndex\n * @param container\n */\nfunction appendHomolog(chrModel, chrIndex, homologIndex, container) {\n\n  var homologOffset, chromosome, shape, defs, adapter;\n\n  defs = d3.select(this.selector + ' defs');\n  // Get chromosome model adapter class\n  adapter = ModelAdapter.getInstance(chrModel);\n\n  // How far this copy of the chromosome is from another\n  homologOffset = homologIndex * this.config.chrMargin;\n\n  // Append chromosome's container\n  chromosome = container\n    .append('g')\n    .attr('id', chrModel.id)\n    .attr('class', 'chromosome ' + adapter.getCssClass())\n    .attr('transform', 'translate(0, ' + homologOffset + ')');\n\n  // Render chromosome\n  shape = Chromosome.getInstance(adapter, this.config, this)\n    .render(chromosome, chrIndex, homologIndex);\n\n  d3.select('#' + chrModel.id + '-chromosome-set-clippath').remove();\n\n  defs.append('clipPath')\n    .attr('id', chrModel.id + '-chromosome-set-clippath')\n    .selectAll('path')\n    .data(shape)\n    .enter()\n    .append('path')\n    .attr('d', function(d) {return d.path;})\n    .attr('class', function(d) {return d.class;});\n}\n\n/**\n * Renders all the bands and outlining boundaries of a chromosome.\n */\nfunction drawChromosome(chrModel) {\n  var chrIndex, container, numChrsInSet, transform, homologIndex,\n    chrSetSelector;\n\n  chrIndex = chrModel.chrIndex;\n\n  transform = this._layout.getChromosomeSetTranslate(chrIndex);\n\n  chrSetSelector = this.selector + ' #' + chrModel.id + '-chromosome-set';\n\n  d3.selectAll(chrSetSelector + ' g').remove();\n\n  container = d3.select(chrSetSelector);\n\n  if (container.nodes().length === 0) {\n    // Append chromosome set container\n    container = d3.select(this.selector)\n      .append('g')\n      .attr('class', 'chromosome-set')\n      .attr('transform', transform)\n      .attr('id', chrModel.id + '-chromosome-set');\n  }\n\n  if (\n    'sex' in this.config &&\n    this.config.ploidy === 2 &&\n    this.sexChromosomes.index === chrIndex\n  ) {\n    this.drawSexChromosomes(container, chrIndex);\n    return;\n  }\n\n  numChrsInSet = 1;\n  if (this.config.ploidy > 1) {\n    numChrsInSet = this._ploidy.getChromosomesNumber(chrIndex);\n  }\n\n  for (homologIndex = 0; homologIndex < numChrsInSet; homologIndex++) {\n    this.appendHomolog(chrModel, chrIndex, homologIndex, container);\n  }\n}\n\n/**\n * Rotates a chromosome 90 degrees and shows or hides all other chromosomes\n * Useful for focusing or defocusing a particular chromosome\n */\nfunction rotateAndToggleDisplay(chrElement) {\n  var chrName, chrModel, chrIndex;\n\n  // Do nothing if taxid not defined. But it should be defined.\n  // To fix that bug we should have a way to find chromosome set number.\n  if (!this.config.taxid) return;\n\n  chrName = chrElement.id.split('-')[0].replace('chr', '');\n  chrModel = this.chromosomes[this.config.taxid][chrName];\n  chrIndex = chrModel.chrIndex;\n\n  this._layout.rotate(chrIndex, chrIndex, chrElement);\n}\n\nfunction setOverflowScroll() {\n  var ideo, config, ideoWidth, ideoInnerWrap, ideoMiddleWrap, ideoSvg,\n    ploidy, ploidyPad;\n\n  ideo = this;\n  config = ideo.config;\n\n  ideoSvg = d3.select(config.container + ' svg#_ideogram');\n  ideoInnerWrap = d3.select(config.container + ' #_ideogramInnerWrap');\n  ideoMiddleWrap = d3.select(config.container + ' #_ideogramMiddleWrap');\n\n  ploidy = config.ploidy;\n  if (ploidy === 1) {\n    ploidyPad = ploidy;\n  } else {\n    ploidyPad = ploidy * 1.12;\n  }\n\n  let annotHeight = 0;\n  if ('annotationsLayout' in config) {\n    annotHeight = config.annotationHeight * config.numAnnotTracks;\n  }\n\n  if (\n    config.orientation === 'vertical' &&\n    config.perspective !== 'comparative' &&\n    config.geometry !== 'collinear'\n  ) {\n    ideoWidth =\n      (ideo.numChromosomes) *\n      (config.chrWidth + config.chrMargin + annotHeight);\n  } else {\n    return;\n  }\n\n  if (config.annotationsLayout === 'heatmap-2d') {\n    return;\n  }\n\n  ideoWidth = Math.ceil(ideoWidth * ploidyPad / config.rows);\n  if (ideo._layout._class === 'SmallLayout') ideoWidth += 100;\n\n  ideoWidth += 35; // Account for settings gear\n\n  // Ensures absolutely-positioned elements, e.g. heatmap overlaps, display\n  // properly if ideogram container also has position: absolute\n  ideoMiddleWrap.style('height', ideo._layout.getHeight() + 'px');\n\n  ideoInnerWrap\n    .style('max-width', ideoWidth + 'px')\n    .style('overflow-x', 'scroll')\n    .style('position', 'absolute');\n\n  ideoSvg.style('min-width', (ideoWidth - 5) + 'px');\n\n  // initSettings(ideo);\n}\n\nexport {\n  appendHomolog, drawChromosome, rotateAndToggleDisplay, setOverflowScroll\n};\n","import {d3} from '../lib';\n\nfunction getChrSetLabelLines(d, i, ideo) {\n  var lines;\n  if (d.name.indexOf(' ') === -1) {\n    lines = [d.name];\n  } else {\n    lines = d.name.match(/^(.*)\\s+([^\\s]+)$/).slice(1).reverse();\n  }\n\n  if (\n    'sex' in ideo.config &&\n    ideo.config.ploidy === 2 &&\n    i === ideo.sexChromosomes.index\n  ) {\n    if (ideo.config.sex === 'male') {\n      lines = ['XY'];\n    } else {\n      lines = ['XX'];\n    }\n  }\n\n  return lines;\n}\n\nfunction renderChromosomeSetLabel(d, i, textElement, ideo) {\n  // Get label lines\n  var lines = getChrSetLabelLines(d, i, ideo);\n\n  // Render label lines\n  d3.select(textElement).selectAll('tspan')\n    .data(lines)\n    .enter()\n    .append('tspan')\n    .attr('dy', function(d, i) {\n      return i * -1.2 + 'em';\n    })\n    .attr('x', ideo._layout.getChromosomeSetLabelXPosition())\n    .attr('class', function(a, i) {\n      var fullLabels = ideo.config.fullChromosomeLabels;\n      return i === 1 && fullLabels ? 'italic' : null;\n    })\n    .text(String);\n}\n\nfunction appendChromosomeSetLabels(ideo) {\n  var layout = ideo._layout;\n\n  d3.selectAll(ideo.selector + ' .chromosome-set')\n    .insert('text', ':first-child')\n    .data(ideo.chromosomesArray)\n    .attr('class', layout.getChromosomeLabelClass())\n    .attr('transform', layout.getChromosomeSetLabelTranslate())\n    .attr('x', layout.getChromosomeSetLabelXPosition())\n    .attr('y', function(d, i) {\n      return layout.getChromosomeSetLabelYPosition(i);\n    })\n    .attr('text-anchor', layout.getChromosomeSetLabelAnchor())\n    .each(function(d, i) {\n      renderChromosomeSetLabel(d, i, this, ideo);\n    });\n}\n\nfunction appendChromosomeLabels(ideo) {\n  var layout = ideo._layout;\n\n  d3.selectAll(ideo.selector + ' .chromosome-set')\n    .each(function(a, chrSetIndex) {\n      d3.select(this).selectAll('.chromosome')\n        .append('text')\n        .attr('class', 'chrLabel')\n        .attr('transform', layout.getChromosomeSetLabelTranslate())\n        .attr('x', function(d, i) {\n          return layout.getChromosomeLabelXPosition(i);\n        })\n        .attr('y', function(d, i) {\n          return layout.getChromosomeLabelYPosition(i);\n        })\n        .text(function(d, chrIndex) {\n          return ideo._ploidy.getAncestor(chrSetIndex, chrIndex);\n        })\n        .attr('text-anchor', 'middle');\n    });\n}\n\n/**\n * Draws labels for each chromosome, e.g. \"1\", \"2\", \"X\".\n * If ideogram configuration has 'fullChromosomeLabels: True',\n * then labels includes name of taxon, which can help when\n * depicting orthologs.\n */\nfunction drawChromosomeLabels() {\n  var ideo = this;\n  appendChromosomeSetLabels(ideo);\n  appendChromosomeLabels(ideo);\n}\n\nfunction getLabelPositionAttrs(scale) {\n  var x, y, scaleSvg;\n\n  if (\n    typeof (scale) !== 'undefined' &&\n    scale.hasOwnProperty('x') &&\n    !(scale.x === 1 && scale.y === 1)\n  ) {\n    scaleSvg = 'scale(' + scale.x + ',' + scale.y + ')';\n    x = -6;\n    y = (scale === '' ? -16 : -14);\n  } else {\n    x = -8;\n    y = -16;\n    scale = {x: 1, y: 1};\n    scaleSvg = '';\n  }\n\n  return {x: x, y: y, scaleSvg: scaleSvg, scale: scale};\n}\n\nfunction updateChrIndex(chrIndex, config) {\n  if (config.numAnnotTracks > 1 || config.orientation === '') chrIndex -= 1;\n  return chrIndex;\n}\n\nfunction rotateVerticalChromosomeLabels(chr, chrIndex, labelPosAttrs, ideo) {\n  var chrMargin2, chrMargin, y,\n    config = ideo.config;\n\n  chrIndex = updateChrIndex(chrIndex, config);\n\n  chrMargin2 = -4;\n  if (config.showBandLabels === true) {\n    chrMargin2 = config.chrMargin + config.chrWidth + 26;\n  }\n\n  chrMargin = config.chrMargin * chrIndex;\n  if (config.numAnnotTracks > 1 === false) chrMargin += 1;\n\n  y = chrMargin + chrMargin2;\n\n  chr.selectAll('text.chrLabel')\n    .attr('transform', labelPosAttrs.scaleSvg)\n    .selectAll('tspan')\n    .attr('x', labelPosAttrs.x)\n    .attr('y', y);\n}\n\nfunction rotateHorizontalChromosomeLabels(chr, chrIndex, labelPosAttrs, ideo) {\n  var chrMargin, chrMargin2, tracksHeight, x,\n    config = ideo.config;\n\n  chrMargin2 = -config.chrWidth - 2;\n  if (config.showBandLabels === true) chrMargin2 = config.chrMargin + 8;\n\n  tracksHeight = config.annotTracksHeight;\n  if (config.annotationsLayout !== 'overlay') tracksHeight *= 2;\n\n  chrMargin = config.chrMargin * chrIndex;\n  x = -(chrMargin + chrMargin2) + 3 + tracksHeight;\n  x /= labelPosAttrs.scale.x;\n\n  chr.selectAll('text.chrLabel')\n    .attr('transform', 'rotate(-90)' + labelPosAttrs.scaleSvg)\n    .selectAll('tspan')\n    .attr('x', x)\n    .attr('y', labelPosAttrs.y);\n}\n\n/**\n * Rotates chromosome labels by 90 degrees, e.g. upon clicking a chromosome.\n */\nfunction rotateChromosomeLabels(chr, chrIndex, orientation, scale) {\n  var labelPosAttrs,\n    ideo = this;\n\n  chrIndex -= 1;\n\n  labelPosAttrs = getLabelPositionAttrs(scale);\n\n  if (orientation === 'vertical' || orientation === '') {\n    rotateVerticalChromosomeLabels(chr, chrIndex, labelPosAttrs, ideo);\n  } else {\n    rotateHorizontalChromosomeLabels(chr, chrIndex, labelPosAttrs, ideo);\n  }\n}\n\nexport {drawChromosomeLabels, rotateChromosomeLabels};\n","/**\n * @fileoverview Kit used in \"Related genes\" example\n *\n * This file simplifies client code for reusing a \"related genes\" ideogram --\n * which finds and displays related genes for a searched gene.\n *\n * Related genes here are either \"interacting genes\" or \"paralogs\".\n * Interacting genes are genes that immediate upstream or downstream of the\n * searched gene in a biochemical pathway. Paralogs are evolutionarily\n * similar genes in the same species.\n *\n * Data sources:\n *   - Interacting genes: WikiPathways\n *   - Paralogs: Ensembl\n *   - Genomic coordinates: Ensembl, via MyGene.info\n *\n * Features provided by this module help users discover and explore genes\n * related to their gene of interest.\n *\n * The reference implementation is available at:\n * https://eweitz.github.io/ideogram/related-genes\n */\n\n/**\n * Determines if interaction node might be a gene\n *\n * Some interaction nodes are biological processes; this filters out many.\n * Filtering these out makes downstream queries faster.\n *\n * ixn {Object} Interaction from WikiPathways\n * gene {Object} Gene from MyGene.info\n */\nfunction maybeGeneSymbol(ixn, gene) {\n  return (\n    ixn !== '' &&\n    !ixn.includes(' ') &&\n    !ixn.includes('/') && // e.g. Akt/PKB\n    ixn.toLowerCase() !== gene.name.toLowerCase()\n  );\n}\n\n/**\n * Retrieves interacting genes from WikiPathways API\n *\n * Docs:\n * https://webservice.wikipathways.org/ui/\n * https://www.wikipathways.org/index.php/Help:WikiPathways_Webservice/API\n *\n * Examples:\n * https://webservice.wikipathways.org/findInteractions?query=ACE2&format=json\n * https://webservice.wikipathways.org/findInteractions?query=RAD51&format=json\n */\nasync function fetchInteractingGenes(gene, ideo) {\n  const ixns = {};\n  const seenNameIds = {};\n  const orgNameSimple = ideo.config.organism.replace(/-/g, ' ');\n  const queryString = `?query=${gene.name}&format=json`;\n  const url =\n    `https://webservice.wikipathways.org/findInteractions${queryString}`;\n\n  const response = await fetch(url);\n  const data = await response.json();\n\n  // For each interaction, get nodes immediately upstream and downstream.\n  // Filter out pathway nodes that are definitely not gene symbols, then\n  // group pathways by (likely) gene symbol. Each interacting gene can have\n  // multiple pathways.\n  data.result.forEach(interaction => {\n    if (interaction.species.toLowerCase() === orgNameSimple) {\n      const right = interaction.fields.right.values;\n      const left = interaction.fields.left.values;\n      const rawIxns = right.concat(left);\n      const name = interaction.name;\n      const id = interaction.id;\n\n      rawIxns.forEach(rawIxn => {\n        const nameId = name + id;\n        if (maybeGeneSymbol(rawIxn, gene) && !(nameId in seenNameIds)) {\n          seenNameIds[nameId] = 1;\n          const ixn = {name: name, pathwayId: id};\n          if (rawIxn in ixns) {\n            ixns[rawIxn].push(ixn);\n          } else {\n            ixns[rawIxn] = [ixn];\n          }\n        }\n      });\n    }\n  });\n\n  return ixns;\n}\n\n/**\n * Queries MyGene.info API, returns parsed JSON\n *\n * Docs:\n * https://docs.mygene.info/en/v3/\n *\n * Example:\n * https://mygene.info/v3/query?q=symbol:cdk2%20OR%20symbol:brca1&species=9606&fields=symbol,genomic_pos,name\n */\nasync function fetchMyGeneInfo(queryString) {\n  const myGeneBase = 'https://mygene.info/v3/query';\n  const response = await fetch(myGeneBase + queryString);\n  const data = await response.json();\n  return data;\n}\n\n/**\n * Summarizes interactions for a gene\n *\n * This comprises most of the content for tooltips for interacting genes.\n */\nfunction describeInteractions(gene, ixns) {\n\n  let description = gene.name;\n\n  if (typeof ixns !== 'undefined') {\n    // ixns is undefined when querying e.g. CDKN1B in human\n    const pathwaysBase = 'https://www.wikipathways.org/index.php/Pathway:';\n    const links = ixns.map(ixn => {\n      const url = `${pathwaysBase}${ixn.pathwayId}`;\n      return `<a href=\"${url}\" target=\"_blank\">${ixn.name}</a>`;\n    }).join('<br/>');\n\n    let pathwayText = 'pathway';\n    if (ixns.length > 1) pathwayText += 's';\n\n    description += `\n      <br/><br/>\n      Interacts in ${pathwayText}:<br/>\n      ${links}`;\n  }\n\n  return description;\n}\n\n/**\n * Retrieves position and other data on interacting genes from MyGene.info\n */\nasync function fetchInteractingGeneAnnots(interactions, ideo) {\n\n  const annots = [];\n  const geneList = Object.keys(interactions);\n\n  if (geneList.length === 0) return annots;\n\n  const ixnParam = geneList.map(ixn => {\n    return `symbol:${ixn.trim()}`;\n  }).join(' OR ');\n\n  const taxid = ideo.config.taxid;\n  const queryString =\n    `?q=${ixnParam}&species=${taxid}&fields=symbol,genomic_pos,name`;\n  const data = await fetchMyGeneInfo(queryString);\n\n  data.hits.forEach(gene => {\n\n    // If hit lacks position, skip processing\n    if ('genomic_pos' in gene === false) return;\n\n    const annot = parseAnnotFromMgiGene(gene, ideo, 'purple');\n    annots.push(annot);\n\n    const ixns = interactions[gene.symbol];\n\n    const description = describeInteractions(gene, ixns);\n\n    ideo.annotDescriptions[gene.symbol] = description;\n  });\n\n  return annots;\n}\n\n/**\n * Fetch paralogs of searched gene\n */\nasync function fetchParalogPositions(annot, annots, ideo) {\n  const taxid = ideo.config.taxid;\n  const orgUnderscored = ideo.config.organism.replace(/[ -]/g, '_');\n\n  const params = `&format=condensed&type=paralogues&target_taxon=${taxid}`;\n  let path = `/homology/id/${annot.id}?${params}`;\n  const ensemblHomologs = await Ideogram.fetchEnsembl(path);\n  const homologs = ensemblHomologs.data[0].homologies;\n\n  // Fetch positions of paralogs\n  const homologIds = homologs.map(homolog => homolog.id);\n  path = '/lookup/id/' + orgUnderscored;\n  const body = {\n    ids: homologIds,\n    species: orgUnderscored,\n    object_type: 'gene'\n  };\n  const ensemblHomologGenes = await Ideogram.fetchEnsembl(path, body, 'POST');\n\n  Object.entries(ensemblHomologGenes).map((idGene, i) => {\n    const gene = idGene[1];\n\n    // Seen in related genes for SIRT2 in Pan troglodytes\n    if ('display_name' in gene === false) return;\n\n    const annot = {\n      name: gene.display_name,\n      chr: gene.seq_region_name,\n      start: gene.start,\n      stop: gene.end,\n      id: gene.id,\n      color: 'pink'\n    };\n\n    // Add to start of array, so searched gene gets top z-index\n    annots.unshift(annot);\n    ideo.annotDescriptions[annot.name] = gene.description;\n  });\n\n  return annots;\n}\n\n/**\n * Transforms MyGene.info (MGI) gene into Ideogram annotation\n */\nfunction parseAnnotFromMgiGene(gene, ideo, color='red') {\n  // Filters out placements on alternative loci scaffolds, an advanced\n  // genome assembly feature we are not concerned with in ideograms.\n  //\n  // Example:\n  // https://mygene.info/v3/query?q=symbol:PTPRC&species=9606&fields=symbol,genomic_pos,name\n  let genomicPos = null;\n  if (Array.isArray(gene.genomic_pos)) {\n    genomicPos = gene.genomic_pos.filter(pos => {\n      return pos.chr in ideo.chromosomes[ideo.config.taxid];\n    })[0];\n  } else {\n    genomicPos = gene.genomic_pos;\n  }\n\n  const annot = {\n    name: gene.symbol,\n    chr: genomicPos.chr,\n    start: genomicPos.start,\n    stop: genomicPos.end,\n    id: genomicPos.ensemblgene,\n    color: color\n  };\n\n  return annot;\n}\n\n/**\n * For given gene, finds and draws interacting genes and paralogs\n *\n * @param geneSymbol {String} Gene symbol, e.g. RAD51\n */\nasync function plotRelatedGenes(geneSymbol) {\n\n  const ideo = this;\n\n  ideo.annotDescriptions = {};\n\n  const ideoSel = ideo.selector;\n  const annotSel = ideoSel + ' .annot';\n  document.querySelectorAll(annotSel).forEach(el => el.remove());\n\n  ideo.startHideAnnotTooltipTimeout();\n\n  // Refine style\n  document.querySelectorAll('.chromosome').forEach(chromosome => {\n    chromosome.style.cursor = '';\n  });\n\n  const chrHeight = ideo.config.chrHeight;\n  const topPx = chrHeight + 30;\n  const leftPx =\n    Array.from(document.querySelectorAll('.chromosome-set'))\n      .slice(-1)[0].getBoundingClientRect().right;\n\n  const style =\n    `float: left; position: relative; top: -${topPx}px; left: ${leftPx}px;`;\n\n  // Fetch positon of searched gene\n  const taxid = ideo.config.taxid;\n  const queryString =\n    `?q=symbol:${geneSymbol}&species=${taxid}&fields=symbol,genomic_pos,name`;\n  const data = await fetchMyGeneInfo(queryString);\n\n  const gene = data.hits[0];\n  ideo.annotDescriptions[gene.symbol] = gene.name;\n\n  let annots = [];\n\n  const annot = parseAnnotFromMgiGene(gene, ideo);\n  annots.push(annot);\n\n  const interactions = await fetchInteractingGenes(annot, ideo);\n  const interactingAnnots =\n    await fetchInteractingGeneAnnots(interactions, ideo);\n  annots = annots.concat(interactingAnnots);\n\n  await fetchParalogPositions(annot, annots, ideo);\n\n  annots.sort((a, b) => {return b.name.length - a.name.length;});\n\n  ideo.drawAnnots(annots);\n\n  document.querySelector('#_ideogramLegend').style = style;\n}\n\n/**\n * Enhance tooltip shown on hovering over gene annotation\n */\nfunction decorateGene(annot) {\n  const ideo = this;\n  const org = ideo.getScientificName(ideo.config.taxid);\n  const term = `(${annot.name}[gene])+AND+(${org}[orgn])`;\n  const url = `https://ncbi.nlm.nih.gov/gene/?term=${term}`;\n  const description = ideo.annotDescriptions[annot.name].split(' [')[0];\n  annot.displayName =\n    `<a target=\"_blank\" href=\"${url}\">${annot.name}</a>\n    <br/>\n    ${description}\n    <br/>`;\n  return annot;\n}\n\nconst shape = 'triangle';\n\nconst legend = [{\n  name: '<b>Click gene to search</b>',\n  rows: [\n    {name: 'Interacting gene', color: 'purple', shape: shape},\n    {name: 'Paralogous gene', color: 'pink', shape: shape},\n    {name: 'Searched gene', color: 'red', shape: shape}\n  ]\n}];\n\n/**\n * Wrapper for Ideogram constructor, with generic \"Related genes\" options\n *\n * This function is made available as a static method on Ideogram.\n *\n * @param {Object} config Ideogram configuration object\n */\nfunction _initRelatedGenes(config) {\n\n  Object.assign(config, {\n    showFullyBanded: false,\n    rotatable: false,\n    legend: legend,\n    onWillShowAnnotTooltip: decorateGene\n  });\n\n  const ideogram = new Ideogram(config);\n\n  return ideogram;\n}\n\nexport {_initRelatedGenes, plotRelatedGenes};\n","/**\n * @fileoverview Core module of Ideogram.js, links all other modules\n * This file defines the Ideogram class, its constructor method, and its\n * static methods.  All instance methods are defined in other modules.\n *\n */\n\nimport version from './version';\n\nimport {\n  configure, initDrawChromosomes, handleRotateOnClick, onLoad,\n  init, finishInit, writeContainer\n} from './init/init';\n\nimport {\n  onLoadAnnots, onDrawAnnots, processAnnotData, restoreDefaultTracks,\n  updateDisplayedTracks, initAnnotSettings, fetchAnnots, drawAnnots,\n  getHistogramBars, drawHeatmaps, deserializeAnnotsForHeatmap, fillAnnots,\n  drawProcessedAnnots, drawSynteny, startHideAnnotTooltipTimeout,\n  showAnnotTooltip, onWillShowAnnotTooltip, setOriginalTrackIndexes,\n  afterRawAnnots, onClickAnnot\n} from './annotations/annotations';\n\nimport {\n  esearch, esummary, elink,\n  getOrganismFromEutils, getTaxids,\n  getAssemblyAndChromosomesFromEutils\n} from './services/services';\n\nimport {\n  drawBandLabels, getBandColorGradients, processBandData,\n  setBandsToShow, hideUnshownBandLabels, drawBandLabelText, drawBandLabelStalk\n} from './bands/bands';\n\nimport {onBrushMove, createBrush} from './brush';\nimport {onCursorMove, createClickCursor} from './cursor';\nimport {drawSexChromosomes, setSexChromosomes} from './sex-chromosomes';\nimport {convertBpToPx, convertPxToBp} from './coordinate-converters';\nimport {\n  unpackAnnots, packAnnots, initCrossFilter, filterAnnots\n} from './filter';\n\nimport {\n  assemblyIsAccession, getDataDir, round, onDidRotate, getSvg, d3,\n  getTaxid, getCommonName, getScientificName, fetch as _fetch\n} from './lib';\n\nimport {\n  getChromosomeModel, getChromosomePixels\n} from './views/chromosome-model';\n\nimport {\n  appendHomolog, drawChromosome, rotateAndToggleDisplay, setOverflowScroll\n} from './views/draw-chromosomes';\n\nimport {\n  drawChromosomeLabels, rotateChromosomeLabels\n} from './views/chromosome-labels.js';\n\nimport {_initRelatedGenes, plotRelatedGenes} from './kit/related-genes';\n\nexport default class Ideogram {\n  constructor(config) {\n\n    // Functions from init.js\n    this.configure = configure;\n    this.initDrawChromosomes = initDrawChromosomes;\n    this.onLoad = onLoad;\n    this.handleRotateOnClick = handleRotateOnClick;\n    this.init = init;\n    this.finishInit = finishInit;\n    this.writeContainer = writeContainer;\n\n    // Functions from annotations.js\n    this.onLoadAnnots = onLoadAnnots;\n    this.onDrawAnnots = onDrawAnnots;\n    this.processAnnotData = processAnnotData;\n    this.restoreDefaultTracks = restoreDefaultTracks;\n    this.updateDisplayedTracks = updateDisplayedTracks;\n    this.initAnnotSettings = initAnnotSettings;\n    this.fetchAnnots = fetchAnnots;\n    this.drawAnnots = drawAnnots;\n    this.getHistogramBars = getHistogramBars;\n    this.drawHeatmaps = drawHeatmaps;\n    this.deserializeAnnotsForHeatmap = deserializeAnnotsForHeatmap;\n    this.fillAnnots = fillAnnots;\n    this.drawProcessedAnnots = drawProcessedAnnots;\n    this.drawSynteny = drawSynteny;\n    this.startHideAnnotTooltipTimeout = startHideAnnotTooltipTimeout;\n    this.showAnnotTooltip = showAnnotTooltip;\n    this.onWillShowAnnotTooltip = onWillShowAnnotTooltip;\n    this.onClickAnnot = onClickAnnot;\n    this.setOriginalTrackIndexes = setOriginalTrackIndexes;\n    this.afterRawAnnots = afterRawAnnots;\n\n    // Variables and functions from services.js\n    this.esearch = esearch;\n    this.esummary = esummary;\n    this.elink = elink;\n    this.getOrganismFromEutils = getOrganismFromEutils;\n    this.getTaxids = getTaxids;\n    this.getAssemblyAndChromosomesFromEutils =\n      getAssemblyAndChromosomesFromEutils;\n\n    // Functions from bands.js\n    this.drawBandLabels = drawBandLabels;\n    this.getBandColorGradients = getBandColorGradients;\n    this.processBandData = processBandData;\n    this.setBandsToShow = setBandsToShow;\n    this.hideUnshownBandLabels = hideUnshownBandLabels;\n    this.drawBandLabelText = drawBandLabelText;\n    this.drawBandLabelStalk = drawBandLabelStalk;\n\n    // Functions from brush.js\n    this.onBrushMove = onBrushMove;\n    this.createBrush = createBrush;\n\n    // Functions from cursor.js\n    this.createClickCursor = createClickCursor;\n    this.onCursorMove = onCursorMove;\n\n    // Functions from sex-chromosomes.js\n    this.drawSexChromosomes = drawSexChromosomes;\n    this.setSexChromosomes = setSexChromosomes;\n\n    // Functions from coordinate-converters.js\n    this.convertBpToPx = convertBpToPx;\n    this.convertPxToBp = convertPxToBp;\n\n    // Functions from filter.js\n    this.unpackAnnots = unpackAnnots;\n    this.packAnnots = packAnnots;\n    this.initCrossFilter = initCrossFilter;\n    this.filterAnnots = filterAnnots;\n\n    // Functions from lib\n    this.assemblyIsAccession = assemblyIsAccession;\n    this.getDataDir = getDataDir;\n    this.round = round;\n    this.onDidRotate = onDidRotate;\n    this.getSvg = getSvg;\n    this.fetch = _fetch;\n    this.getTaxid = getTaxid;\n    this.getCommonName = getCommonName;\n    this.getScientificName = getScientificName;\n\n    // Functions from views/chromosome-model.js\n    this.getChromosomeModel = getChromosomeModel;\n    this.getChromosomePixels = getChromosomePixels;\n\n    // Functions from views/chromosome-labels.js\n    this.drawChromosomeLabels = drawChromosomeLabels;\n    this.rotateChromosomeLabels = rotateChromosomeLabels;\n\n    // Functions from views/draw-chromosomes.js\n    this.appendHomolog = appendHomolog;\n    this.drawChromosome = drawChromosome;\n    this.rotateAndToggleDisplay = rotateAndToggleDisplay;\n    this.setOverflowScroll = setOverflowScroll;\n\n    this.plotRelatedGenes = plotRelatedGenes;\n\n    this.configure(config);\n  }\n\n  /**\n   * Get the current version of Ideogram.js\n   */\n  static get version() {\n    return version;\n  }\n\n  /**\n  * Enable use of D3 in client apps, via \"d3 = Ideogram.d3\"\n  */\n  static get d3() {\n    return d3;\n  }\n\n  /**\n   * Request data from Ensembl REST API\n   * Docs: https://rest.ensembl.org/\n   *\n   * @param {String} path URL path\n   * @param {Object} body POST body\n   * @param {String} method HTTP method; 'GET' (default) or 'POST'\n   */\n  static async fetchEnsembl(path, body = null, method = 'GET') {\n    const init = {\n      method: method,\n      headers: {'Content-Type': 'application/json'}\n    };\n    if (body !== null) init.body = JSON.stringify(body);\n    const response = await fetch(`https://rest.ensembl.org${path}`, init);\n    const json = await response.json();\n    return json;\n  }\n\n  /**\n   * Sorts two chromosome objects by type and name\n   * - Nuclear chromosomes come before non-nuclear chromosomes.\n   * - Among nuclear chromosomes, use \"natural sorting\", e.g.\n   *   numbers come before letters\n   * - Among non-nuclear chromosomes, i.e. \"MT\" (mitochondrial DNA) and\n   *   \"CP\" (chromoplast DNA), MT comes first\n   *\n   *\n   * @param a Chromosome object \"A\"\n   * @param b Chromosome object \"B\"\n   * @returns {Number} JavaScript sort order indicator\n   */\n  static sortChromosomes(a, b) {\n    var aIsNuclear = a.type === 'nuclear',\n      bIsNuclear = b.type === 'nuclear',\n      aIsCP = a.type === 'chloroplast',\n      bIsCP = b.type === 'chloroplast',\n      aIsMT = a.type === 'mitochondrion',\n      bIsMT = b.type === 'mitochondrion',\n      aIsAP = a.type === 'apicoplast',\n      bIsAP = b.type === 'apicoplast';\n    // e.g. B1 in rice genome GCF_001433935.1\n    // aIsPlastid = aIsMT && a.name !== 'MT',\n    // bIsPlastid = bIsMT && b.name !== 'MT';\n\n    if (aIsNuclear && bIsNuclear) {\n      return a.name.localeCompare(b.name, 'en', {numeric: true});\n    } else if (!aIsNuclear && bIsNuclear) {\n      return 1;\n    } else if (aIsMT && bIsCP) {\n      return 1;\n    } else if (aIsCP && bIsMT) {\n      return -1;\n    } else if (!aIsAP && !aIsMT && !aIsCP && (bIsMT || bIsCP || bIsAP)) {\n      return -1;\n    }\n  }\n\n  /**\n   * Wrapper for Ideogram constructor, with generic \"Related genes\" options\n   *\n   * @param {Object} config Ideogram configuration object\n   */\n  static initRelatedGenes(config) {\n    return _initRelatedGenes(config);\n  }\n}\n","var version = '1.21.0';\nexport default version;\n","import Ideogram from './ideogram';\n\n// Enable references to Ideogram when loaded via traditional script tag\nwindow.Ideogram = Ideogram;\n\n// Enable references to Ideogram when imported as an ES6 module\nexport default Ideogram;\n"],"sourceRoot":""}
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\t\tmodule.l = true;\n\n \t\t// Return the exports of the module\n \t\treturn module.exports;\n \t}\n\n\n \t// expose the modules object (__webpack_modules__)\n \t__webpack_require__.m = modules;\n\n \t// expose the module cache\n \t__webpack_require__.c = installedModules;\n\n \t// define getter function for harmony exports\n \t__webpack_require__.d = function(exports, name, getter) {\n \t\tif(!__webpack_require__.o(exports, name)) {\n \t\t\tObject.defineProperty(exports, name, { enumerable: true, get: getter });\n \t\t}\n \t};\n\n \t// define __esModule on exports\n \t__webpack_require__.r = function(exports) {\n \t\tif(typeof Symbol !== 'undefined' && Symbol.toStringTag) {\n \t\t\tObject.defineProperty(exports, Symbol.toStringTag, { value: 'Module' });\n \t\t}\n \t\tObject.defineProperty(exports, '__esModule', { value: true });\n \t};\n\n \t// create a fake namespace object\n \t// mode & 1: value is a module id, require it\n \t// mode & 2: merge all properties of value into the ns\n \t// mode & 4: return value when already ns object\n \t// mode & 8|1: behave like require\n \t__webpack_require__.t = function(value, mode) {\n \t\tif(mode & 1) value = __webpack_require__(value);\n \t\tif(mode & 8) return value;\n \t\tif((mode & 4) && typeof value === 'object' && value && value.__esModule) return value;\n \t\tvar ns = Object.create(null);\n \t\t__webpack_require__.r(ns);\n \t\tObject.defineProperty(ns, 'default', { enumerable: true, value: value });\n \t\tif(mode & 2 && typeof value != 'string') for(var key in value) __webpack_require__.d(ns, key, function(key) { return value[key]; }.bind(null, key));\n \t\treturn ns;\n \t};\n\n \t// getDefaultExport function for compatibility with non-harmony modules\n \t__webpack_require__.n = function(module) {\n \t\tvar getter = module && module.__esModule ?\n \t\t\tfunction getDefault() { return module['default']; } :\n \t\t\tfunction getModuleExports() { return module; };\n \t\t__webpack_require__.d(getter, 'a', getter);\n \t\treturn getter;\n \t};\n\n \t// Object.prototype.hasOwnProperty.call\n \t__webpack_require__.o = function(object, property) { return Object.prototype.hasOwnProperty.call(object, property); };\n\n \t// __webpack_public_path__\n \t__webpack_require__.p = \"/dist/js\";\n\n\n \t// Load entry module and return exports\n \treturn __webpack_require__(__webpack_require__.s = 5);\n","function none() {}\n\nexport default function(selector) {\n  return selector == null ? none : function() {\n    return this.querySelector(selector);\n  };\n}\n","function empty() {\n  return [];\n}\n\nexport default function(selector) {\n  return selector == null ? empty : function() {\n    return this.querySelectorAll(selector);\n  };\n}\n","export default function(selector) {\n  return function() {\n    return this.matches(selector);\n  };\n}\n","export default function(update) {\n  return new Array(update.length);\n}\n","import sparse from \"./sparse\";\nimport {Selection} from \"./index\";\n\nexport default function() {\n  return new Selection(this._enter || this._groups.map(sparse), this._parents);\n}\n\nexport function EnterNode(parent, datum) {\n  this.ownerDocument = parent.ownerDocument;\n  this.namespaceURI = parent.namespaceURI;\n  this._next = null;\n  this._parent = parent;\n  this.__data__ = datum;\n}\n\nEnterNode.prototype = {\n  constructor: EnterNode,\n  appendChild: function(child) { return this._parent.insertBefore(child, this._next); },\n  insertBefore: function(child, next) { return this._parent.insertBefore(child, next); },\n  querySelector: function(selector) { return this._parent.querySelector(selector); },\n  querySelectorAll: function(selector) { return this._parent.querySelectorAll(selector); }\n};\n","import {Selection} from \"./index\";\nimport {EnterNode} from \"./enter\";\nimport constant from \"../constant\";\n\nvar keyPrefix = \"$\"; // Protect against keys like “__proto__”.\n\nfunction bindIndex(parent, group, enter, update, exit, data) {\n  var i = 0,\n      node,\n      groupLength = group.length,\n      dataLength = data.length;\n\n  // Put any non-null nodes that fit into update.\n  // Put any null nodes into enter.\n  // Put any remaining data into enter.\n  for (; i < dataLength; ++i) {\n    if (node = group[i]) {\n      node.__data__ = data[i];\n      update[i] = node;\n    } else {\n      enter[i] = new EnterNode(parent, data[i]);\n    }\n  }\n\n  // Put any non-null nodes that don’t fit into exit.\n  for (; i < groupLength; ++i) {\n    if (node = group[i]) {\n      exit[i] = node;\n    }\n  }\n}\n\nfunction bindKey(parent, group, enter, update, exit, data, key) {\n  var i,\n      node,\n      nodeByKeyValue = {},\n      groupLength = group.length,\n      dataLength = data.length,\n      keyValues = new Array(groupLength),\n      keyValue;\n\n  // Compute the key for each node.\n  // If multiple nodes have the same key, the duplicates are added to exit.\n  for (i = 0; i < groupLength; ++i) {\n    if (node = group[i]) {\n      keyValues[i] = keyValue = keyPrefix + key.call(node, node.__data__, i, group);\n      if (keyValue in nodeByKeyValue) {\n        exit[i] = node;\n      } else {\n        nodeByKeyValue[keyValue] = node;\n      }\n    }\n  }\n\n  // Compute the key for each datum.\n  // If there a node associated with this key, join and add it to update.\n  // If there is not (or the key is a duplicate), add it to enter.\n  for (i = 0; i < dataLength; ++i) {\n    keyValue = keyPrefix + key.call(parent, data[i], i, data);\n    if (node = nodeByKeyValue[keyValue]) {\n      update[i] = node;\n      node.__data__ = data[i];\n      nodeByKeyValue[keyValue] = null;\n    } else {\n      enter[i] = new EnterNode(parent, data[i]);\n    }\n  }\n\n  // Add any remaining nodes that were not bound to data to exit.\n  for (i = 0; i < groupLength; ++i) {\n    if ((node = group[i]) && (nodeByKeyValue[keyValues[i]] === node)) {\n      exit[i] = node;\n    }\n  }\n}\n\nexport default function(value, key) {\n  if (!value) {\n    data = new Array(this.size()), j = -1;\n    this.each(function(d) { data[++j] = d; });\n    return data;\n  }\n\n  var bind = key ? bindKey : bindIndex,\n      parents = this._parents,\n      groups = this._groups;\n\n  if (typeof value !== \"function\") value = constant(value);\n\n  for (var m = groups.length, update = new Array(m), enter = new Array(m), exit = new Array(m), j = 0; j < m; ++j) {\n    var parent = parents[j],\n        group = groups[j],\n        groupLength = group.length,\n        data = value.call(parent, parent && parent.__data__, j, parents),\n        dataLength = data.length,\n        enterGroup = enter[j] = new Array(dataLength),\n        updateGroup = update[j] = new Array(dataLength),\n        exitGroup = exit[j] = new Array(groupLength);\n\n    bind(parent, group, enterGroup, updateGroup, exitGroup, data, key);\n\n    // Now connect the enter nodes to their following update node, such that\n    // appendChild can insert the materialized enter node before this node,\n    // rather than at the end of the parent node.\n    for (var i0 = 0, i1 = 0, previous, next; i0 < dataLength; ++i0) {\n      if (previous = enterGroup[i0]) {\n        if (i0 >= i1) i1 = i0 + 1;\n        while (!(next = updateGroup[i1]) && ++i1 < dataLength);\n        previous._next = next || null;\n      }\n    }\n  }\n\n  update = new Selection(update, parents);\n  update._enter = enter;\n  update._exit = exit;\n  return update;\n}\n","import {Selection} from \"./index\";\n\nexport default function(compare) {\n  if (!compare) compare = ascending;\n\n  function compareNode(a, b) {\n    return a && b ? compare(a.__data__, b.__data__) : !a - !b;\n  }\n\n  for (var groups = this._groups, m = groups.length, sortgroups = new Array(m), j = 0; j < m; ++j) {\n    for (var group = groups[j], n = group.length, sortgroup = sortgroups[j] = new Array(n), node, i = 0; i < n; ++i) {\n      if (node = group[i]) {\n        sortgroup[i] = node;\n      }\n    }\n    sortgroup.sort(compareNode);\n  }\n\n  return new Selection(sortgroups, this._parents).order();\n}\n\nfunction ascending(a, b) {\n  return a < b ? -1 : a > b ? 1 : a >= b ? 0 : NaN;\n}\n","export default function() {\n  var callback = arguments[0];\n  arguments[0] = this;\n  callback.apply(null, arguments);\n  return this;\n}\n","export var xhtml = \"http://www.w3.org/1999/xhtml\";\n\nexport default {\n  svg: \"http://www.w3.org/2000/svg\",\n  xhtml: xhtml,\n  xlink: \"http://www.w3.org/1999/xlink\",\n  xml: \"http://www.w3.org/XML/1998/namespace\",\n  xmlns: \"http://www.w3.org/2000/xmlns/\"\n};\n","import namespaces from \"./namespaces\";\n\nexport default function(name) {\n  var prefix = name += \"\", i = prefix.indexOf(\":\");\n  if (i >= 0 && (prefix = name.slice(0, i)) !== \"xmlns\") name = name.slice(i + 1);\n  return namespaces.hasOwnProperty(prefix) ? {space: namespaces[prefix], local: name} : name;\n}\n","import namespace from \"../namespace\";\n\nfunction attrRemove(name) {\n  return function() {\n    this.removeAttribute(name);\n  };\n}\n\nfunction attrRemoveNS(fullname) {\n  return function() {\n    this.removeAttributeNS(fullname.space, fullname.local);\n  };\n}\n\nfunction attrConstant(name, value) {\n  return function() {\n    this.setAttribute(name, value);\n  };\n}\n\nfunction attrConstantNS(fullname, value) {\n  return function() {\n    this.setAttributeNS(fullname.space, fullname.local, value);\n  };\n}\n\nfunction attrFunction(name, value) {\n  return function() {\n    var v = value.apply(this, arguments);\n    if (v == null) this.removeAttribute(name);\n    else this.setAttribute(name, v);\n  };\n}\n\nfunction attrFunctionNS(fullname, value) {\n  return function() {\n    var v = value.apply(this, arguments);\n    if (v == null) this.removeAttributeNS(fullname.space, fullname.local);\n    else this.setAttributeNS(fullname.space, fullname.local, v);\n  };\n}\n\nexport default function(name, value) {\n  var fullname = namespace(name);\n\n  if (arguments.length < 2) {\n    var node = this.node();\n    return fullname.local\n        ? node.getAttributeNS(fullname.space, fullname.local)\n        : node.getAttribute(fullname);\n  }\n\n  return this.each((value == null\n      ? (fullname.local ? attrRemoveNS : attrRemove) : (typeof value === \"function\"\n      ? (fullname.local ? attrFunctionNS : attrFunction)\n      : (fullname.local ? attrConstantNS : attrConstant)))(fullname, value));\n}\n","export default function(node) {\n  return (node.ownerDocument && node.ownerDocument.defaultView) // node is a Node\n      || (node.document && node) // node is a Window\n      || node.defaultView; // node is a Document\n}\n","import defaultView from \"../window\";\n\nfunction styleRemove(name) {\n  return function() {\n    this.style.removeProperty(name);\n  };\n}\n\nfunction styleConstant(name, value, priority) {\n  return function() {\n    this.style.setProperty(name, value, priority);\n  };\n}\n\nfunction styleFunction(name, value, priority) {\n  return function() {\n    var v = value.apply(this, arguments);\n    if (v == null) this.style.removeProperty(name);\n    else this.style.setProperty(name, v, priority);\n  };\n}\n\nexport default function(name, value, priority) {\n  return arguments.length > 1\n      ? this.each((value == null\n            ? styleRemove : typeof value === \"function\"\n            ? styleFunction\n            : styleConstant)(name, value, priority == null ? \"\" : priority))\n      : styleValue(this.node(), name);\n}\n\nexport function styleValue(node, name) {\n  return node.style.getPropertyValue(name)\n      || defaultView(node).getComputedStyle(node, null).getPropertyValue(name);\n}\n","function propertyRemove(name) {\n  return function() {\n    delete this[name];\n  };\n}\n\nfunction propertyConstant(name, value) {\n  return function() {\n    this[name] = value;\n  };\n}\n\nfunction propertyFunction(name, value) {\n  return function() {\n    var v = value.apply(this, arguments);\n    if (v == null) delete this[name];\n    else this[name] = v;\n  };\n}\n\nexport default function(name, value) {\n  return arguments.length > 1\n      ? this.each((value == null\n          ? propertyRemove : typeof value === \"function\"\n          ? propertyFunction\n          : propertyConstant)(name, value))\n      : this.node()[name];\n}\n","function classArray(string) {\n  return string.trim().split(/^|\\s+/);\n}\n\nfunction classList(node) {\n  return node.classList || new ClassList(node);\n}\n\nfunction ClassList(node) {\n  this._node = node;\n  this._names = classArray(node.getAttribute(\"class\") || \"\");\n}\n\nClassList.prototype = {\n  add: function(name) {\n    var i = this._names.indexOf(name);\n    if (i < 0) {\n      this._names.push(name);\n      this._node.setAttribute(\"class\", this._names.join(\" \"));\n    }\n  },\n  remove: function(name) {\n    var i = this._names.indexOf(name);\n    if (i >= 0) {\n      this._names.splice(i, 1);\n      this._node.setAttribute(\"class\", this._names.join(\" \"));\n    }\n  },\n  contains: function(name) {\n    return this._names.indexOf(name) >= 0;\n  }\n};\n\nfunction classedAdd(node, names) {\n  var list = classList(node), i = -1, n = names.length;\n  while (++i < n) list.add(names[i]);\n}\n\nfunction classedRemove(node, names) {\n  var list = classList(node), i = -1, n = names.length;\n  while (++i < n) list.remove(names[i]);\n}\n\nfunction classedTrue(names) {\n  return function() {\n    classedAdd(this, names);\n  };\n}\n\nfunction classedFalse(names) {\n  return function() {\n    classedRemove(this, names);\n  };\n}\n\nfunction classedFunction(names, value) {\n  return function() {\n    (value.apply(this, arguments) ? classedAdd : classedRemove)(this, names);\n  };\n}\n\nexport default function(name, value) {\n  var names = classArray(name + \"\");\n\n  if (arguments.length < 2) {\n    var list = classList(this.node()), i = -1, n = names.length;\n    while (++i < n) if (!list.contains(names[i])) return false;\n    return true;\n  }\n\n  return this.each((typeof value === \"function\"\n      ? classedFunction : value\n      ? classedTrue\n      : classedFalse)(names, value));\n}\n","function textRemove() {\n  this.textContent = \"\";\n}\n\nfunction textConstant(value) {\n  return function() {\n    this.textContent = value;\n  };\n}\n\nfunction textFunction(value) {\n  return function() {\n    var v = value.apply(this, arguments);\n    this.textContent = v == null ? \"\" : v;\n  };\n}\n\nexport default function(value) {\n  return arguments.length\n      ? this.each(value == null\n          ? textRemove : (typeof value === \"function\"\n          ? textFunction\n          : textConstant)(value))\n      : this.node().textContent;\n}\n","function htmlRemove() {\n  this.innerHTML = \"\";\n}\n\nfunction htmlConstant(value) {\n  return function() {\n    this.innerHTML = value;\n  };\n}\n\nfunction htmlFunction(value) {\n  return function() {\n    var v = value.apply(this, arguments);\n    this.innerHTML = v == null ? \"\" : v;\n  };\n}\n\nexport default function(value) {\n  return arguments.length\n      ? this.each(value == null\n          ? htmlRemove : (typeof value === \"function\"\n          ? htmlFunction\n          : htmlConstant)(value))\n      : this.node().innerHTML;\n}\n","function raise() {\n  if (this.nextSibling) this.parentNode.appendChild(this);\n}\n\nexport default function() {\n  return this.each(raise);\n}\n","function lower() {\n  if (this.previousSibling) this.parentNode.insertBefore(this, this.parentNode.firstChild);\n}\n\nexport default function() {\n  return this.each(lower);\n}\n","import namespace from \"./namespace\";\nimport {xhtml} from \"./namespaces\";\n\nfunction creatorInherit(name) {\n  return function() {\n    var document = this.ownerDocument,\n        uri = this.namespaceURI;\n    return uri === xhtml && document.documentElement.namespaceURI === xhtml\n        ? document.createElement(name)\n        : document.createElementNS(uri, name);\n  };\n}\n\nfunction creatorFixed(fullname) {\n  return function() {\n    return this.ownerDocument.createElementNS(fullname.space, fullname.local);\n  };\n}\n\nexport default function(name) {\n  var fullname = namespace(name);\n  return (fullname.local\n      ? creatorFixed\n      : creatorInherit)(fullname);\n}\n","import creator from \"../creator\";\nimport selector from \"../selector\";\n\nfunction constantNull() {\n  return null;\n}\n\nexport default function(name, before) {\n  var create = typeof name === \"function\" ? name : creator(name),\n      select = before == null ? constantNull : typeof before === \"function\" ? before : selector(before);\n  return this.select(function() {\n    return this.insertBefore(create.apply(this, arguments), select.apply(this, arguments) || null);\n  });\n}\n","function remove() {\n  var parent = this.parentNode;\n  if (parent) parent.removeChild(this);\n}\n\nexport default function() {\n  return this.each(remove);\n}\n","function selection_cloneShallow() {\n  var clone = this.cloneNode(false), parent = this.parentNode;\n  return parent ? parent.insertBefore(clone, this.nextSibling) : clone;\n}\n\nfunction selection_cloneDeep() {\n  var clone = this.cloneNode(true), parent = this.parentNode;\n  return parent ? parent.insertBefore(clone, this.nextSibling) : clone;\n}\n\nexport default function(deep) {\n  return this.select(deep ? selection_cloneDeep : selection_cloneShallow);\n}\n","var filterEvents = {};\n\nexport var event = null;\n\nif (typeof document !== \"undefined\") {\n  var element = document.documentElement;\n  if (!(\"onmouseenter\" in element)) {\n    filterEvents = {mouseenter: \"mouseover\", mouseleave: \"mouseout\"};\n  }\n}\n\nfunction filterContextListener(listener, index, group) {\n  listener = contextListener(listener, index, group);\n  return function(event) {\n    var related = event.relatedTarget;\n    if (!related || (related !== this && !(related.compareDocumentPosition(this) & 8))) {\n      listener.call(this, event);\n    }\n  };\n}\n\nfunction contextListener(listener, index, group) {\n  return function(event1) {\n    var event0 = event; // Events can be reentrant (e.g., focus).\n    event = event1;\n    try {\n      listener.call(this, this.__data__, index, group);\n    } finally {\n      event = event0;\n    }\n  };\n}\n\nfunction parseTypenames(typenames) {\n  return typenames.trim().split(/^|\\s+/).map(function(t) {\n    var name = \"\", i = t.indexOf(\".\");\n    if (i >= 0) name = t.slice(i + 1), t = t.slice(0, i);\n    return {type: t, name: name};\n  });\n}\n\nfunction onRemove(typename) {\n  return function() {\n    var on = this.__on;\n    if (!on) return;\n    for (var j = 0, i = -1, m = on.length, o; j < m; ++j) {\n      if (o = on[j], (!typename.type || o.type === typename.type) && o.name === typename.name) {\n        this.removeEventListener(o.type, o.listener, o.capture);\n      } else {\n        on[++i] = o;\n      }\n    }\n    if (++i) on.length = i;\n    else delete this.__on;\n  };\n}\n\nfunction onAdd(typename, value, capture) {\n  var wrap = filterEvents.hasOwnProperty(typename.type) ? filterContextListener : contextListener;\n  return function(d, i, group) {\n    var on = this.__on, o, listener = wrap(value, i, group);\n    if (on) for (var j = 0, m = on.length; j < m; ++j) {\n      if ((o = on[j]).type === typename.type && o.name === typename.name) {\n        this.removeEventListener(o.type, o.listener, o.capture);\n        this.addEventListener(o.type, o.listener = listener, o.capture = capture);\n        o.value = value;\n        return;\n      }\n    }\n    this.addEventListener(typename.type, listener, capture);\n    o = {type: typename.type, name: typename.name, value: value, listener: listener, capture: capture};\n    if (!on) this.__on = [o];\n    else on.push(o);\n  };\n}\n\nexport default function(typename, value, capture) {\n  var typenames = parseTypenames(typename + \"\"), i, n = typenames.length, t;\n\n  if (arguments.length < 2) {\n    var on = this.node().__on;\n    if (on) for (var j = 0, m = on.length, o; j < m; ++j) {\n      for (i = 0, o = on[j]; i < n; ++i) {\n        if ((t = typenames[i]).type === o.type && t.name === o.name) {\n          return o.value;\n        }\n      }\n    }\n    return;\n  }\n\n  on = value ? onAdd : onRemove;\n  if (capture == null) capture = false;\n  for (i = 0; i < n; ++i) this.each(on(typenames[i], value, capture));\n  return this;\n}\n\nexport function customEvent(event1, listener, that, args) {\n  var event0 = event;\n  event1.sourceEvent = event;\n  event = event1;\n  try {\n    return listener.apply(that, args);\n  } finally {\n    event = event0;\n  }\n}\n","import defaultView from \"../window\";\n\nfunction dispatchEvent(node, type, params) {\n  var window = defaultView(node),\n      event = window.CustomEvent;\n\n  if (typeof event === \"function\") {\n    event = new event(type, params);\n  } else {\n    event = window.document.createEvent(\"Event\");\n    if (params) event.initEvent(type, params.bubbles, params.cancelable), event.detail = params.detail;\n    else event.initEvent(type, false, false);\n  }\n\n  node.dispatchEvent(event);\n}\n\nfunction dispatchConstant(type, params) {\n  return function() {\n    return dispatchEvent(this, type, params);\n  };\n}\n\nfunction dispatchFunction(type, params) {\n  return function() {\n    return dispatchEvent(this, type, params.apply(this, arguments));\n  };\n}\n\nexport default function(type, params) {\n  return this.each((typeof params === \"function\"\n      ? dispatchFunction\n      : dispatchConstant)(type, params));\n}\n","import selection_select from \"./select\";\nimport selection_selectAll from \"./selectAll\";\nimport selection_filter from \"./filter\";\nimport selection_data from \"./data\";\nimport selection_enter from \"./enter\";\nimport selection_exit from \"./exit\";\nimport selection_join from \"./join\";\nimport selection_merge from \"./merge\";\nimport selection_order from \"./order\";\nimport selection_sort from \"./sort\";\nimport selection_call from \"./call\";\nimport selection_nodes from \"./nodes\";\nimport selection_node from \"./node\";\nimport selection_size from \"./size\";\nimport selection_empty from \"./empty\";\nimport selection_each from \"./each\";\nimport selection_attr from \"./attr\";\nimport selection_style from \"./style\";\nimport selection_property from \"./property\";\nimport selection_classed from \"./classed\";\nimport selection_text from \"./text\";\nimport selection_html from \"./html\";\nimport selection_raise from \"./raise\";\nimport selection_lower from \"./lower\";\nimport selection_append from \"./append\";\nimport selection_insert from \"./insert\";\nimport selection_remove from \"./remove\";\nimport selection_clone from \"./clone\";\nimport selection_datum from \"./datum\";\nimport selection_on from \"./on\";\nimport selection_dispatch from \"./dispatch\";\n\nexport var root = [null];\n\nexport function Selection(groups, parents) {\n  this._groups = groups;\n  this._parents = parents;\n}\n\nfunction selection() {\n  return new Selection([[document.documentElement]], root);\n}\n\nSelection.prototype = selection.prototype = {\n  constructor: Selection,\n  select: selection_select,\n  selectAll: selection_selectAll,\n  filter: selection_filter,\n  data: selection_data,\n  enter: selection_enter,\n  exit: selection_exit,\n  join: selection_join,\n  merge: selection_merge,\n  order: selection_order,\n  sort: selection_sort,\n  call: selection_call,\n  nodes: selection_nodes,\n  node: selection_node,\n  size: selection_size,\n  empty: selection_empty,\n  each: selection_each,\n  attr: selection_attr,\n  style: selection_style,\n  property: selection_property,\n  classed: selection_classed,\n  text: selection_text,\n  html: selection_html,\n  raise: selection_raise,\n  lower: selection_lower,\n  append: selection_append,\n  insert: selection_insert,\n  remove: selection_remove,\n  clone: selection_clone,\n  datum: selection_datum,\n  on: selection_on,\n  dispatch: selection_dispatch\n};\n\nexport default selection;\n","import {Selection} from \"./index\";\nimport selector from \"../selector\";\n\nexport default function(select) {\n  if (typeof select !== \"function\") select = selector(select);\n\n  for (var groups = this._groups, m = groups.length, subgroups = new Array(m), j = 0; j < m; ++j) {\n    for (var group = groups[j], n = group.length, subgroup = subgroups[j] = new Array(n), node, subnode, i = 0; i < n; ++i) {\n      if ((node = group[i]) && (subnode = select.call(node, node.__data__, i, group))) {\n        if (\"__data__\" in node) subnode.__data__ = node.__data__;\n        subgroup[i] = subnode;\n      }\n    }\n  }\n\n  return new Selection(subgroups, this._parents);\n}\n","import {Selection} from \"./index\";\nimport selectorAll from \"../selectorAll\";\n\nexport default function(select) {\n  if (typeof select !== \"function\") select = selectorAll(select);\n\n  for (var groups = this._groups, m = groups.length, subgroups = [], parents = [], j = 0; j < m; ++j) {\n    for (var group = groups[j], n = group.length, node, i = 0; i < n; ++i) {\n      if (node = group[i]) {\n        subgroups.push(select.call(node, node.__data__, i, group));\n        parents.push(node);\n      }\n    }\n  }\n\n  return new Selection(subgroups, parents);\n}\n","import {Selection} from \"./index\";\nimport matcher from \"../matcher\";\n\nexport default function(match) {\n  if (typeof match !== \"function\") match = matcher(match);\n\n  for (var groups = this._groups, m = groups.length, subgroups = new Array(m), j = 0; j < m; ++j) {\n    for (var group = groups[j], n = group.length, subgroup = subgroups[j] = [], node, i = 0; i < n; ++i) {\n      if ((node = group[i]) && match.call(node, node.__data__, i, group)) {\n        subgroup.push(node);\n      }\n    }\n  }\n\n  return new Selection(subgroups, this._parents);\n}\n","export default function(x) {\n  return function() {\n    return x;\n  };\n}\n","import sparse from \"./sparse\";\nimport {Selection} from \"./index\";\n\nexport default function() {\n  return new Selection(this._exit || this._groups.map(sparse), this._parents);\n}\n","export default function(onenter, onupdate, onexit) {\n  var enter = this.enter(), update = this, exit = this.exit();\n  enter = typeof onenter === \"function\" ? onenter(enter) : enter.append(onenter + \"\");\n  if (onupdate != null) update = onupdate(update);\n  if (onexit == null) exit.remove(); else onexit(exit);\n  return enter && update ? enter.merge(update).order() : update;\n}\n","import {Selection} from \"./index\";\n\nexport default function(selection) {\n\n  for (var groups0 = this._groups, groups1 = selection._groups, m0 = groups0.length, m1 = groups1.length, m = Math.min(m0, m1), merges = new Array(m0), j = 0; j < m; ++j) {\n    for (var group0 = groups0[j], group1 = groups1[j], n = group0.length, merge = merges[j] = new Array(n), node, i = 0; i < n; ++i) {\n      if (node = group0[i] || group1[i]) {\n        merge[i] = node;\n      }\n    }\n  }\n\n  for (; j < m0; ++j) {\n    merges[j] = groups0[j];\n  }\n\n  return new Selection(merges, this._parents);\n}\n","export default function() {\n\n  for (var groups = this._groups, j = -1, m = groups.length; ++j < m;) {\n    for (var group = groups[j], i = group.length - 1, next = group[i], node; --i >= 0;) {\n      if (node = group[i]) {\n        if (next && node.compareDocumentPosition(next) ^ 4) next.parentNode.insertBefore(node, next);\n        next = node;\n      }\n    }\n  }\n\n  return this;\n}\n","export default function() {\n  var nodes = new Array(this.size()), i = -1;\n  this.each(function() { nodes[++i] = this; });\n  return nodes;\n}\n","export default function() {\n\n  for (var groups = this._groups, j = 0, m = groups.length; j < m; ++j) {\n    for (var group = groups[j], i = 0, n = group.length; i < n; ++i) {\n      var node = group[i];\n      if (node) return node;\n    }\n  }\n\n  return null;\n}\n","export default function() {\n  var size = 0;\n  this.each(function() { ++size; });\n  return size;\n}\n","export default function() {\n  return !this.node();\n}\n","export default function(callback) {\n\n  for (var groups = this._groups, j = 0, m = groups.length; j < m; ++j) {\n    for (var group = groups[j], i = 0, n = group.length, node; i < n; ++i) {\n      if (node = group[i]) callback.call(node, node.__data__, i, group);\n    }\n  }\n\n  return this;\n}\n","import creator from \"../creator\";\n\nexport default function(name) {\n  var create = typeof name === \"function\" ? name : creator(name);\n  return this.select(function() {\n    return this.appendChild(create.apply(this, arguments));\n  });\n}\n","export default function(value) {\n  return arguments.length\n      ? this.property(\"__data__\", value)\n      : this.node().__data__;\n}\n","import {Selection, root} from \"./selection/index\";\n\nexport default function(selector) {\n  return typeof selector === \"string\"\n      ? new Selection([[document.querySelector(selector)]], [document.documentElement])\n      : new Selection([[selector]], root);\n}\n","function responseBlob(response) {\n  if (!response.ok) throw new Error(response.status + \" \" + response.statusText);\n  return response.blob();\n}\n\nexport default function(input, init) {\n  return fetch(input, init).then(responseBlob);\n}\n","function responseArrayBuffer(response) {\n  if (!response.ok) throw new Error(response.status + \" \" + response.statusText);\n  return response.arrayBuffer();\n}\n\nexport default function(input, init) {\n  return fetch(input, init).then(responseArrayBuffer);\n}\n","var EOL = {},\n    EOF = {},\n    QUOTE = 34,\n    NEWLINE = 10,\n    RETURN = 13;\n\nfunction objectConverter(columns) {\n  return new Function(\"d\", \"return {\" + columns.map(function(name, i) {\n    return JSON.stringify(name) + \": d[\" + i + \"] || \\\"\\\"\";\n  }).join(\",\") + \"}\");\n}\n\nfunction customConverter(columns, f) {\n  var object = objectConverter(columns);\n  return function(row, i) {\n    return f(object(row), i, columns);\n  };\n}\n\n// Compute unique columns in order of discovery.\nfunction inferColumns(rows) {\n  var columnSet = Object.create(null),\n      columns = [];\n\n  rows.forEach(function(row) {\n    for (var column in row) {\n      if (!(column in columnSet)) {\n        columns.push(columnSet[column] = column);\n      }\n    }\n  });\n\n  return columns;\n}\n\nfunction pad(value, width) {\n  var s = value + \"\", length = s.length;\n  return length < width ? new Array(width - length + 1).join(0) + s : s;\n}\n\nfunction formatYear(year) {\n  return year < 0 ? \"-\" + pad(-year, 6)\n    : year > 9999 ? \"+\" + pad(year, 6)\n    : pad(year, 4);\n}\n\nfunction formatDate(date) {\n  var hours = date.getUTCHours(),\n      minutes = date.getUTCMinutes(),\n      seconds = date.getUTCSeconds(),\n      milliseconds = date.getUTCMilliseconds();\n  return isNaN(date) ? \"Invalid Date\"\n      : formatYear(date.getUTCFullYear(), 4) + \"-\" + pad(date.getUTCMonth() + 1, 2) + \"-\" + pad(date.getUTCDate(), 2)\n      + (milliseconds ? \"T\" + pad(hours, 2) + \":\" + pad(minutes, 2) + \":\" + pad(seconds, 2) + \".\" + pad(milliseconds, 3) + \"Z\"\n      : seconds ? \"T\" + pad(hours, 2) + \":\" + pad(minutes, 2) + \":\" + pad(seconds, 2) + \"Z\"\n      : minutes || hours ? \"T\" + pad(hours, 2) + \":\" + pad(minutes, 2) + \"Z\"\n      : \"\");\n}\n\nexport default function(delimiter) {\n  var reFormat = new RegExp(\"[\\\"\" + delimiter + \"\\n\\r]\"),\n      DELIMITER = delimiter.charCodeAt(0);\n\n  function parse(text, f) {\n    var convert, columns, rows = parseRows(text, function(row, i) {\n      if (convert) return convert(row, i - 1);\n      columns = row, convert = f ? customConverter(row, f) : objectConverter(row);\n    });\n    rows.columns = columns || [];\n    return rows;\n  }\n\n  function parseRows(text, f) {\n    var rows = [], // output rows\n        N = text.length,\n        I = 0, // current character index\n        n = 0, // current line number\n        t, // current token\n        eof = N <= 0, // current token followed by EOF?\n        eol = false; // current token followed by EOL?\n\n    // Strip the trailing newline.\n    if (text.charCodeAt(N - 1) === NEWLINE) --N;\n    if (text.charCodeAt(N - 1) === RETURN) --N;\n\n    function token() {\n      if (eof) return EOF;\n      if (eol) return eol = false, EOL;\n\n      // Unescape quotes.\n      var i, j = I, c;\n      if (text.charCodeAt(j) === QUOTE) {\n        while (I++ < N && text.charCodeAt(I) !== QUOTE || text.charCodeAt(++I) === QUOTE);\n        if ((i = I) >= N) eof = true;\n        else if ((c = text.charCodeAt(I++)) === NEWLINE) eol = true;\n        else if (c === RETURN) { eol = true; if (text.charCodeAt(I) === NEWLINE) ++I; }\n        return text.slice(j + 1, i - 1).replace(/\"\"/g, \"\\\"\");\n      }\n\n      // Find next delimiter or newline.\n      while (I < N) {\n        if ((c = text.charCodeAt(i = I++)) === NEWLINE) eol = true;\n        else if (c === RETURN) { eol = true; if (text.charCodeAt(I) === NEWLINE) ++I; }\n        else if (c !== DELIMITER) continue;\n        return text.slice(j, i);\n      }\n\n      // Return last token before EOF.\n      return eof = true, text.slice(j, N);\n    }\n\n    while ((t = token()) !== EOF) {\n      var row = [];\n      while (t !== EOL && t !== EOF) row.push(t), t = token();\n      if (f && (row = f(row, n++)) == null) continue;\n      rows.push(row);\n    }\n\n    return rows;\n  }\n\n  function preformatBody(rows, columns) {\n    return rows.map(function(row) {\n      return columns.map(function(column) {\n        return formatValue(row[column]);\n      }).join(delimiter);\n    });\n  }\n\n  function format(rows, columns) {\n    if (columns == null) columns = inferColumns(rows);\n    return [columns.map(formatValue).join(delimiter)].concat(preformatBody(rows, columns)).join(\"\\n\");\n  }\n\n  function formatBody(rows, columns) {\n    if (columns == null) columns = inferColumns(rows);\n    return preformatBody(rows, columns).join(\"\\n\");\n  }\n\n  function formatRows(rows) {\n    return rows.map(formatRow).join(\"\\n\");\n  }\n\n  function formatRow(row) {\n    return row.map(formatValue).join(delimiter);\n  }\n\n  function formatValue(value) {\n    return value == null ? \"\"\n        : value instanceof Date ? formatDate(value)\n        : reFormat.test(value += \"\") ? \"\\\"\" + value.replace(/\"/g, \"\\\"\\\"\") + \"\\\"\"\n        : value;\n  }\n\n  return {\n    parse: parse,\n    parseRows: parseRows,\n    format: format,\n    formatBody: formatBody,\n    formatRows: formatRows,\n    formatRow: formatRow,\n    formatValue: formatValue\n  };\n}\n","import dsv from \"./dsv.js\";\n\nvar csv = dsv(\",\");\n\nexport var csvParse = csv.parse;\nexport var csvParseRows = csv.parseRows;\nexport var csvFormat = csv.format;\nexport var csvFormatBody = csv.formatBody;\nexport var csvFormatRows = csv.formatRows;\nexport var csvFormatRow = csv.formatRow;\nexport var csvFormatValue = csv.formatValue;\n","import dsv from \"./dsv.js\";\n\nvar tsv = dsv(\"\\t\");\n\nexport var tsvParse = tsv.parse;\nexport var tsvParseRows = tsv.parseRows;\nexport var tsvFormat = tsv.format;\nexport var tsvFormatBody = tsv.formatBody;\nexport var tsvFormatRows = tsv.formatRows;\nexport var tsvFormatRow = tsv.formatRow;\nexport var tsvFormatValue = tsv.formatValue;\n","function responseText(response) {\n  if (!response.ok) throw new Error(response.status + \" \" + response.statusText);\n  return response.text();\n}\n\nexport default function(input, init) {\n  return fetch(input, init).then(responseText);\n}\n","import {csvParse, dsvFormat, tsvParse} from \"d3-dsv\";\nimport text from \"./text\";\n\nfunction dsvParse(parse) {\n  return function(input, init, row) {\n    if (arguments.length === 2 && typeof init === \"function\") row = init, init = undefined;\n    return text(input, init).then(function(response) {\n      return parse(response, row);\n    });\n  };\n}\n\nexport default function dsv(delimiter, input, init, row) {\n  if (arguments.length === 3 && typeof init === \"function\") row = init, init = undefined;\n  var format = dsvFormat(delimiter);\n  return text(input, init).then(function(response) {\n    return format.parse(response, row);\n  });\n}\n\nexport var csv = dsvParse(csvParse);\nexport var tsv = dsvParse(tsvParse);\n","export default function(input, init) {\n  return new Promise(function(resolve, reject) {\n    var image = new Image;\n    for (var key in init) image[key] = init[key];\n    image.onerror = reject;\n    image.onload = function() { resolve(image); };\n    image.src = input;\n  });\n}\n","function responseJson(response) {\n  if (!response.ok) throw new Error(response.status + \" \" + response.statusText);\n  return response.json();\n}\n\nexport default function(input, init) {\n  return fetch(input, init).then(responseJson);\n}\n","import text from \"./text\";\n\nfunction parser(type) {\n  return function(input, init)  {\n    return text(input, init).then(function(text) {\n      return (new DOMParser).parseFromString(text, type);\n    });\n  };\n}\n\nexport default parser(\"application/xml\");\n\nexport var html = parser(\"text/html\");\n\nexport var svg = parser(\"image/svg+xml\");\n","var noop = {value: function() {}};\n\nfunction dispatch() {\n  for (var i = 0, n = arguments.length, _ = {}, t; i < n; ++i) {\n    if (!(t = arguments[i] + \"\") || (t in _) || /[\\s.]/.test(t)) throw new Error(\"illegal type: \" + t);\n    _[t] = [];\n  }\n  return new Dispatch(_);\n}\n\nfunction Dispatch(_) {\n  this._ = _;\n}\n\nfunction parseTypenames(typenames, types) {\n  return typenames.trim().split(/^|\\s+/).map(function(t) {\n    var name = \"\", i = t.indexOf(\".\");\n    if (i >= 0) name = t.slice(i + 1), t = t.slice(0, i);\n    if (t && !types.hasOwnProperty(t)) throw new Error(\"unknown type: \" + t);\n    return {type: t, name: name};\n  });\n}\n\nDispatch.prototype = dispatch.prototype = {\n  constructor: Dispatch,\n  on: function(typename, callback) {\n    var _ = this._,\n        T = parseTypenames(typename + \"\", _),\n        t,\n        i = -1,\n        n = T.length;\n\n    // If no callback was specified, return the callback of the given type and name.\n    if (arguments.length < 2) {\n      while (++i < n) if ((t = (typename = T[i]).type) && (t = get(_[t], typename.name))) return t;\n      return;\n    }\n\n    // If a type was specified, set the callback for the given type and name.\n    // Otherwise, if a null callback was specified, remove callbacks of the given name.\n    if (callback != null && typeof callback !== \"function\") throw new Error(\"invalid callback: \" + callback);\n    while (++i < n) {\n      if (t = (typename = T[i]).type) _[t] = set(_[t], typename.name, callback);\n      else if (callback == null) for (t in _) _[t] = set(_[t], typename.name, null);\n    }\n\n    return this;\n  },\n  copy: function() {\n    var copy = {}, _ = this._;\n    for (var t in _) copy[t] = _[t].slice();\n    return new Dispatch(copy);\n  },\n  call: function(type, that) {\n    if ((n = arguments.length - 2) > 0) for (var args = new Array(n), i = 0, n, t; i < n; ++i) args[i] = arguments[i + 2];\n    if (!this._.hasOwnProperty(type)) throw new Error(\"unknown type: \" + type);\n    for (t = this._[type], i = 0, n = t.length; i < n; ++i) t[i].value.apply(that, args);\n  },\n  apply: function(type, that, args) {\n    if (!this._.hasOwnProperty(type)) throw new Error(\"unknown type: \" + type);\n    for (var t = this._[type], i = 0, n = t.length; i < n; ++i) t[i].value.apply(that, args);\n  }\n};\n\nfunction get(type, name) {\n  for (var i = 0, n = type.length, c; i < n; ++i) {\n    if ((c = type[i]).name === name) {\n      return c.value;\n    }\n  }\n}\n\nfunction set(type, name, callback) {\n  for (var i = 0, n = type.length; i < n; ++i) {\n    if (type[i].name === name) {\n      type[i] = noop, type = type.slice(0, i).concat(type.slice(i + 1));\n      break;\n    }\n  }\n  if (callback != null) type.push({name: name, value: callback});\n  return type;\n}\n\nexport default dispatch;\n","import {event} from \"d3-selection\";\n\nexport function nopropagation() {\n  event.stopImmediatePropagation();\n}\n\nexport default function() {\n  event.preventDefault();\n  event.stopImmediatePropagation();\n}\n","import {select} from \"d3-selection\";\nimport noevent from \"./noevent.js\";\n\nexport default function(view) {\n  var root = view.document.documentElement,\n      selection = select(view).on(\"dragstart.drag\", noevent, true);\n  if (\"onselectstart\" in root) {\n    selection.on(\"selectstart.drag\", noevent, true);\n  } else {\n    root.__noselect = root.style.MozUserSelect;\n    root.style.MozUserSelect = \"none\";\n  }\n}\n\nexport function yesdrag(view, noclick) {\n  var root = view.document.documentElement,\n      selection = select(view).on(\"dragstart.drag\", null);\n  if (noclick) {\n    selection.on(\"click.drag\", noevent, true);\n    setTimeout(function() { selection.on(\"click.drag\", null); }, 0);\n  }\n  if (\"onselectstart\" in root) {\n    selection.on(\"selectstart.drag\", null);\n  } else {\n    root.style.MozUserSelect = root.__noselect;\n    delete root.__noselect;\n  }\n}\n","export default function(constructor, factory, prototype) {\n  constructor.prototype = factory.prototype = prototype;\n  prototype.constructor = constructor;\n}\n\nexport function extend(parent, definition) {\n  var prototype = Object.create(parent.prototype);\n  for (var key in definition) prototype[key] = definition[key];\n  return prototype;\n}\n","import define, {extend} from \"./define.js\";\n\nexport function Color() {}\n\nexport var darker = 0.7;\nexport var brighter = 1 / darker;\n\nvar reI = \"\\\\s*([+-]?\\\\d+)\\\\s*\",\n    reN = \"\\\\s*([+-]?\\\\d*\\\\.?\\\\d+(?:[eE][+-]?\\\\d+)?)\\\\s*\",\n    reP = \"\\\\s*([+-]?\\\\d*\\\\.?\\\\d+(?:[eE][+-]?\\\\d+)?)%\\\\s*\",\n    reHex = /^#([0-9a-f]{3,8})$/,\n    reRgbInteger = new RegExp(\"^rgb\\\\(\" + [reI, reI, reI] + \"\\\\)$\"),\n    reRgbPercent = new RegExp(\"^rgb\\\\(\" + [reP, reP, reP] + \"\\\\)$\"),\n    reRgbaInteger = new RegExp(\"^rgba\\\\(\" + [reI, reI, reI, reN] + \"\\\\)$\"),\n    reRgbaPercent = new RegExp(\"^rgba\\\\(\" + [reP, reP, reP, reN] + \"\\\\)$\"),\n    reHslPercent = new RegExp(\"^hsl\\\\(\" + [reN, reP, reP] + \"\\\\)$\"),\n    reHslaPercent = new RegExp(\"^hsla\\\\(\" + [reN, reP, reP, reN] + \"\\\\)$\");\n\nvar named = {\n  aliceblue: 0xf0f8ff,\n  antiquewhite: 0xfaebd7,\n  aqua: 0x00ffff,\n  aquamarine: 0x7fffd4,\n  azure: 0xf0ffff,\n  beige: 0xf5f5dc,\n  bisque: 0xffe4c4,\n  black: 0x000000,\n  blanchedalmond: 0xffebcd,\n  blue: 0x0000ff,\n  blueviolet: 0x8a2be2,\n  brown: 0xa52a2a,\n  burlywood: 0xdeb887,\n  cadetblue: 0x5f9ea0,\n  chartreuse: 0x7fff00,\n  chocolate: 0xd2691e,\n  coral: 0xff7f50,\n  cornflowerblue: 0x6495ed,\n  cornsilk: 0xfff8dc,\n  crimson: 0xdc143c,\n  cyan: 0x00ffff,\n  darkblue: 0x00008b,\n  darkcyan: 0x008b8b,\n  darkgoldenrod: 0xb8860b,\n  darkgray: 0xa9a9a9,\n  darkgreen: 0x006400,\n  darkgrey: 0xa9a9a9,\n  darkkhaki: 0xbdb76b,\n  darkmagenta: 0x8b008b,\n  darkolivegreen: 0x556b2f,\n  darkorange: 0xff8c00,\n  darkorchid: 0x9932cc,\n  darkred: 0x8b0000,\n  darksalmon: 0xe9967a,\n  darkseagreen: 0x8fbc8f,\n  darkslateblue: 0x483d8b,\n  darkslategray: 0x2f4f4f,\n  darkslategrey: 0x2f4f4f,\n  darkturquoise: 0x00ced1,\n  darkviolet: 0x9400d3,\n  deeppink: 0xff1493,\n  deepskyblue: 0x00bfff,\n  dimgray: 0x696969,\n  dimgrey: 0x696969,\n  dodgerblue: 0x1e90ff,\n  firebrick: 0xb22222,\n  floralwhite: 0xfffaf0,\n  forestgreen: 0x228b22,\n  fuchsia: 0xff00ff,\n  gainsboro: 0xdcdcdc,\n  ghostwhite: 0xf8f8ff,\n  gold: 0xffd700,\n  goldenrod: 0xdaa520,\n  gray: 0x808080,\n  green: 0x008000,\n  greenyellow: 0xadff2f,\n  grey: 0x808080,\n  honeydew: 0xf0fff0,\n  hotpink: 0xff69b4,\n  indianred: 0xcd5c5c,\n  indigo: 0x4b0082,\n  ivory: 0xfffff0,\n  khaki: 0xf0e68c,\n  lavender: 0xe6e6fa,\n  lavenderblush: 0xfff0f5,\n  lawngreen: 0x7cfc00,\n  lemonchiffon: 0xfffacd,\n  lightblue: 0xadd8e6,\n  lightcoral: 0xf08080,\n  lightcyan: 0xe0ffff,\n  lightgoldenrodyellow: 0xfafad2,\n  lightgray: 0xd3d3d3,\n  lightgreen: 0x90ee90,\n  lightgrey: 0xd3d3d3,\n  lightpink: 0xffb6c1,\n  lightsalmon: 0xffa07a,\n  lightseagreen: 0x20b2aa,\n  lightskyblue: 0x87cefa,\n  lightslategray: 0x778899,\n  lightslategrey: 0x778899,\n  lightsteelblue: 0xb0c4de,\n  lightyellow: 0xffffe0,\n  lime: 0x00ff00,\n  limegreen: 0x32cd32,\n  linen: 0xfaf0e6,\n  magenta: 0xff00ff,\n  maroon: 0x800000,\n  mediumaquamarine: 0x66cdaa,\n  mediumblue: 0x0000cd,\n  mediumorchid: 0xba55d3,\n  mediumpurple: 0x9370db,\n  mediumseagreen: 0x3cb371,\n  mediumslateblue: 0x7b68ee,\n  mediumspringgreen: 0x00fa9a,\n  mediumturquoise: 0x48d1cc,\n  mediumvioletred: 0xc71585,\n  midnightblue: 0x191970,\n  mintcream: 0xf5fffa,\n  mistyrose: 0xffe4e1,\n  moccasin: 0xffe4b5,\n  navajowhite: 0xffdead,\n  navy: 0x000080,\n  oldlace: 0xfdf5e6,\n  olive: 0x808000,\n  olivedrab: 0x6b8e23,\n  orange: 0xffa500,\n  orangered: 0xff4500,\n  orchid: 0xda70d6,\n  palegoldenrod: 0xeee8aa,\n  palegreen: 0x98fb98,\n  paleturquoise: 0xafeeee,\n  palevioletred: 0xdb7093,\n  papayawhip: 0xffefd5,\n  peachpuff: 0xffdab9,\n  peru: 0xcd853f,\n  pink: 0xffc0cb,\n  plum: 0xdda0dd,\n  powderblue: 0xb0e0e6,\n  purple: 0x800080,\n  rebeccapurple: 0x663399,\n  red: 0xff0000,\n  rosybrown: 0xbc8f8f,\n  royalblue: 0x4169e1,\n  saddlebrown: 0x8b4513,\n  salmon: 0xfa8072,\n  sandybrown: 0xf4a460,\n  seagreen: 0x2e8b57,\n  seashell: 0xfff5ee,\n  sienna: 0xa0522d,\n  silver: 0xc0c0c0,\n  skyblue: 0x87ceeb,\n  slateblue: 0x6a5acd,\n  slategray: 0x708090,\n  slategrey: 0x708090,\n  snow: 0xfffafa,\n  springgreen: 0x00ff7f,\n  steelblue: 0x4682b4,\n  tan: 0xd2b48c,\n  teal: 0x008080,\n  thistle: 0xd8bfd8,\n  tomato: 0xff6347,\n  turquoise: 0x40e0d0,\n  violet: 0xee82ee,\n  wheat: 0xf5deb3,\n  white: 0xffffff,\n  whitesmoke: 0xf5f5f5,\n  yellow: 0xffff00,\n  yellowgreen: 0x9acd32\n};\n\ndefine(Color, color, {\n  copy: function(channels) {\n    return Object.assign(new this.constructor, this, channels);\n  },\n  displayable: function() {\n    return this.rgb().displayable();\n  },\n  hex: color_formatHex, // Deprecated! Use color.formatHex.\n  formatHex: color_formatHex,\n  formatHsl: color_formatHsl,\n  formatRgb: color_formatRgb,\n  toString: color_formatRgb\n});\n\nfunction color_formatHex() {\n  return this.rgb().formatHex();\n}\n\nfunction color_formatHsl() {\n  return hslConvert(this).formatHsl();\n}\n\nfunction color_formatRgb() {\n  return this.rgb().formatRgb();\n}\n\nexport default function color(format) {\n  var m, l;\n  format = (format + \"\").trim().toLowerCase();\n  return (m = reHex.exec(format)) ? (l = m[1].length, m = parseInt(m[1], 16), l === 6 ? rgbn(m) // #ff0000\n      : l === 3 ? new Rgb((m >> 8 & 0xf) | (m >> 4 & 0xf0), (m >> 4 & 0xf) | (m & 0xf0), ((m & 0xf) << 4) | (m & 0xf), 1) // #f00\n      : l === 8 ? new Rgb(m >> 24 & 0xff, m >> 16 & 0xff, m >> 8 & 0xff, (m & 0xff) / 0xff) // #ff000000\n      : l === 4 ? new Rgb((m >> 12 & 0xf) | (m >> 8 & 0xf0), (m >> 8 & 0xf) | (m >> 4 & 0xf0), (m >> 4 & 0xf) | (m & 0xf0), (((m & 0xf) << 4) | (m & 0xf)) / 0xff) // #f000\n      : null) // invalid hex\n      : (m = reRgbInteger.exec(format)) ? new Rgb(m[1], m[2], m[3], 1) // rgb(255, 0, 0)\n      : (m = reRgbPercent.exec(format)) ? new Rgb(m[1] * 255 / 100, m[2] * 255 / 100, m[3] * 255 / 100, 1) // rgb(100%, 0%, 0%)\n      : (m = reRgbaInteger.exec(format)) ? rgba(m[1], m[2], m[3], m[4]) // rgba(255, 0, 0, 1)\n      : (m = reRgbaPercent.exec(format)) ? rgba(m[1] * 255 / 100, m[2] * 255 / 100, m[3] * 255 / 100, m[4]) // rgb(100%, 0%, 0%, 1)\n      : (m = reHslPercent.exec(format)) ? hsla(m[1], m[2] / 100, m[3] / 100, 1) // hsl(120, 50%, 50%)\n      : (m = reHslaPercent.exec(format)) ? hsla(m[1], m[2] / 100, m[3] / 100, m[4]) // hsla(120, 50%, 50%, 1)\n      : named.hasOwnProperty(format) ? rgbn(named[format]) // eslint-disable-line no-prototype-builtins\n      : format === \"transparent\" ? new Rgb(NaN, NaN, NaN, 0)\n      : null;\n}\n\nfunction rgbn(n) {\n  return new Rgb(n >> 16 & 0xff, n >> 8 & 0xff, n & 0xff, 1);\n}\n\nfunction rgba(r, g, b, a) {\n  if (a <= 0) r = g = b = NaN;\n  return new Rgb(r, g, b, a);\n}\n\nexport function rgbConvert(o) {\n  if (!(o instanceof Color)) o = color(o);\n  if (!o) return new Rgb;\n  o = o.rgb();\n  return new Rgb(o.r, o.g, o.b, o.opacity);\n}\n\nexport function rgb(r, g, b, opacity) {\n  return arguments.length === 1 ? rgbConvert(r) : new Rgb(r, g, b, opacity == null ? 1 : opacity);\n}\n\nexport function Rgb(r, g, b, opacity) {\n  this.r = +r;\n  this.g = +g;\n  this.b = +b;\n  this.opacity = +opacity;\n}\n\ndefine(Rgb, rgb, extend(Color, {\n  brighter: function(k) {\n    k = k == null ? brighter : Math.pow(brighter, k);\n    return new Rgb(this.r * k, this.g * k, this.b * k, this.opacity);\n  },\n  darker: function(k) {\n    k = k == null ? darker : Math.pow(darker, k);\n    return new Rgb(this.r * k, this.g * k, this.b * k, this.opacity);\n  },\n  rgb: function() {\n    return this;\n  },\n  displayable: function() {\n    return (-0.5 <= this.r && this.r < 255.5)\n        && (-0.5 <= this.g && this.g < 255.5)\n        && (-0.5 <= this.b && this.b < 255.5)\n        && (0 <= this.opacity && this.opacity <= 1);\n  },\n  hex: rgb_formatHex, // Deprecated! Use color.formatHex.\n  formatHex: rgb_formatHex,\n  formatRgb: rgb_formatRgb,\n  toString: rgb_formatRgb\n}));\n\nfunction rgb_formatHex() {\n  return \"#\" + hex(this.r) + hex(this.g) + hex(this.b);\n}\n\nfunction rgb_formatRgb() {\n  var a = this.opacity; a = isNaN(a) ? 1 : Math.max(0, Math.min(1, a));\n  return (a === 1 ? \"rgb(\" : \"rgba(\")\n      + Math.max(0, Math.min(255, Math.round(this.r) || 0)) + \", \"\n      + Math.max(0, Math.min(255, Math.round(this.g) || 0)) + \", \"\n      + Math.max(0, Math.min(255, Math.round(this.b) || 0))\n      + (a === 1 ? \")\" : \", \" + a + \")\");\n}\n\nfunction hex(value) {\n  value = Math.max(0, Math.min(255, Math.round(value) || 0));\n  return (value < 16 ? \"0\" : \"\") + value.toString(16);\n}\n\nfunction hsla(h, s, l, a) {\n  if (a <= 0) h = s = l = NaN;\n  else if (l <= 0 || l >= 1) h = s = NaN;\n  else if (s <= 0) h = NaN;\n  return new Hsl(h, s, l, a);\n}\n\nexport function hslConvert(o) {\n  if (o instanceof Hsl) return new Hsl(o.h, o.s, o.l, o.opacity);\n  if (!(o instanceof Color)) o = color(o);\n  if (!o) return new Hsl;\n  if (o instanceof Hsl) return o;\n  o = o.rgb();\n  var r = o.r / 255,\n      g = o.g / 255,\n      b = o.b / 255,\n      min = Math.min(r, g, b),\n      max = Math.max(r, g, b),\n      h = NaN,\n      s = max - min,\n      l = (max + min) / 2;\n  if (s) {\n    if (r === max) h = (g - b) / s + (g < b) * 6;\n    else if (g === max) h = (b - r) / s + 2;\n    else h = (r - g) / s + 4;\n    s /= l < 0.5 ? max + min : 2 - max - min;\n    h *= 60;\n  } else {\n    s = l > 0 && l < 1 ? 0 : h;\n  }\n  return new Hsl(h, s, l, o.opacity);\n}\n\nexport function hsl(h, s, l, opacity) {\n  return arguments.length === 1 ? hslConvert(h) : new Hsl(h, s, l, opacity == null ? 1 : opacity);\n}\n\nfunction Hsl(h, s, l, opacity) {\n  this.h = +h;\n  this.s = +s;\n  this.l = +l;\n  this.opacity = +opacity;\n}\n\ndefine(Hsl, hsl, extend(Color, {\n  brighter: function(k) {\n    k = k == null ? brighter : Math.pow(brighter, k);\n    return new Hsl(this.h, this.s, this.l * k, this.opacity);\n  },\n  darker: function(k) {\n    k = k == null ? darker : Math.pow(darker, k);\n    return new Hsl(this.h, this.s, this.l * k, this.opacity);\n  },\n  rgb: function() {\n    var h = this.h % 360 + (this.h < 0) * 360,\n        s = isNaN(h) || isNaN(this.s) ? 0 : this.s,\n        l = this.l,\n        m2 = l + (l < 0.5 ? l : 1 - l) * s,\n        m1 = 2 * l - m2;\n    return new Rgb(\n      hsl2rgb(h >= 240 ? h - 240 : h + 120, m1, m2),\n      hsl2rgb(h, m1, m2),\n      hsl2rgb(h < 120 ? h + 240 : h - 120, m1, m2),\n      this.opacity\n    );\n  },\n  displayable: function() {\n    return (0 <= this.s && this.s <= 1 || isNaN(this.s))\n        && (0 <= this.l && this.l <= 1)\n        && (0 <= this.opacity && this.opacity <= 1);\n  },\n  formatHsl: function() {\n    var a = this.opacity; a = isNaN(a) ? 1 : Math.max(0, Math.min(1, a));\n    return (a === 1 ? \"hsl(\" : \"hsla(\")\n        + (this.h || 0) + \", \"\n        + (this.s || 0) * 100 + \"%, \"\n        + (this.l || 0) * 100 + \"%\"\n        + (a === 1 ? \")\" : \", \" + a + \")\");\n  }\n}));\n\n/* From FvD 13.37, CSS Color Module Level 3 */\nfunction hsl2rgb(h, m1, m2) {\n  return (h < 60 ? m1 + (m2 - m1) * h / 60\n      : h < 180 ? m2\n      : h < 240 ? m1 + (m2 - m1) * (240 - h) / 60\n      : m1) * 255;\n}\n","export function basis(t1, v0, v1, v2, v3) {\n  var t2 = t1 * t1, t3 = t2 * t1;\n  return ((1 - 3 * t1 + 3 * t2 - t3) * v0\n      + (4 - 6 * t2 + 3 * t3) * v1\n      + (1 + 3 * t1 + 3 * t2 - 3 * t3) * v2\n      + t3 * v3) / 6;\n}\n\nexport default function(values) {\n  var n = values.length - 1;\n  return function(t) {\n    var i = t <= 0 ? (t = 0) : t >= 1 ? (t = 1, n - 1) : Math.floor(t * n),\n        v1 = values[i],\n        v2 = values[i + 1],\n        v0 = i > 0 ? values[i - 1] : 2 * v1 - v2,\n        v3 = i < n - 1 ? values[i + 2] : 2 * v2 - v1;\n    return basis((t - i / n) * n, v0, v1, v2, v3);\n  };\n}\n","export default function(x) {\n  return function() {\n    return x;\n  };\n}\n","import constant from \"./constant.js\";\n\nfunction linear(a, d) {\n  return function(t) {\n    return a + t * d;\n  };\n}\n\nfunction exponential(a, b, y) {\n  return a = Math.pow(a, y), b = Math.pow(b, y) - a, y = 1 / y, function(t) {\n    return Math.pow(a + t * b, y);\n  };\n}\n\nexport function hue(a, b) {\n  var d = b - a;\n  return d ? linear(a, d > 180 || d < -180 ? d - 360 * Math.round(d / 360) : d) : constant(isNaN(a) ? b : a);\n}\n\nexport function gamma(y) {\n  return (y = +y) === 1 ? nogamma : function(a, b) {\n    return b - a ? exponential(a, b, y) : constant(isNaN(a) ? b : a);\n  };\n}\n\nexport default function nogamma(a, b) {\n  var d = b - a;\n  return d ? linear(a, d) : constant(isNaN(a) ? b : a);\n}\n","import {rgb as colorRgb} from \"d3-color\";\nimport basis from \"./basis.js\";\nimport basisClosed from \"./basisClosed.js\";\nimport nogamma, {gamma} from \"./color.js\";\n\nexport default (function rgbGamma(y) {\n  var color = gamma(y);\n\n  function rgb(start, end) {\n    var r = color((start = colorRgb(start)).r, (end = colorRgb(end)).r),\n        g = color(start.g, end.g),\n        b = color(start.b, end.b),\n        opacity = nogamma(start.opacity, end.opacity);\n    return function(t) {\n      start.r = r(t);\n      start.g = g(t);\n      start.b = b(t);\n      start.opacity = opacity(t);\n      return start + \"\";\n    };\n  }\n\n  rgb.gamma = rgbGamma;\n\n  return rgb;\n})(1);\n\nfunction rgbSpline(spline) {\n  return function(colors) {\n    var n = colors.length,\n        r = new Array(n),\n        g = new Array(n),\n        b = new Array(n),\n        i, color;\n    for (i = 0; i < n; ++i) {\n      color = colorRgb(colors[i]);\n      r[i] = color.r || 0;\n      g[i] = color.g || 0;\n      b[i] = color.b || 0;\n    }\n    r = spline(r);\n    g = spline(g);\n    b = spline(b);\n    color.opacity = 1;\n    return function(t) {\n      color.r = r(t);\n      color.g = g(t);\n      color.b = b(t);\n      return color + \"\";\n    };\n  };\n}\n\nexport var rgbBasis = rgbSpline(basis);\nexport var rgbBasisClosed = rgbSpline(basisClosed);\n","import {basis} from \"./basis.js\";\n\nexport default function(values) {\n  var n = values.length;\n  return function(t) {\n    var i = Math.floor(((t %= 1) < 0 ? ++t : t) * n),\n        v0 = values[(i + n - 1) % n],\n        v1 = values[i % n],\n        v2 = values[(i + 1) % n],\n        v3 = values[(i + 2) % n];\n    return basis((t - i / n) * n, v0, v1, v2, v3);\n  };\n}\n","export default function(a, b) {\n  if (!b) b = [];\n  var n = a ? Math.min(b.length, a.length) : 0,\n      c = b.slice(),\n      i;\n  return function(t) {\n    for (i = 0; i < n; ++i) c[i] = a[i] * (1 - t) + b[i] * t;\n    return c;\n  };\n}\n\nexport function isNumberArray(x) {\n  return ArrayBuffer.isView(x) && !(x instanceof DataView);\n}\n","import value from \"./value.js\";\nimport numberArray, {isNumberArray} from \"./numberArray.js\";\n\nexport default function(a, b) {\n  return (isNumberArray(b) ? numberArray : genericArray)(a, b);\n}\n\nexport function genericArray(a, b) {\n  var nb = b ? b.length : 0,\n      na = a ? Math.min(nb, a.length) : 0,\n      x = new Array(na),\n      c = new Array(nb),\n      i;\n\n  for (i = 0; i < na; ++i) x[i] = value(a[i], b[i]);\n  for (; i < nb; ++i) c[i] = b[i];\n\n  return function(t) {\n    for (i = 0; i < na; ++i) c[i] = x[i](t);\n    return c;\n  };\n}\n","export default function(a, b) {\n  var d = new Date;\n  return a = +a, b = +b, function(t) {\n    return d.setTime(a * (1 - t) + b * t), d;\n  };\n}\n","export default function(a, b) {\n  return a = +a, b = +b, function(t) {\n    return a * (1 - t) + b * t;\n  };\n}\n","import value from \"./value.js\";\n\nexport default function(a, b) {\n  var i = {},\n      c = {},\n      k;\n\n  if (a === null || typeof a !== \"object\") a = {};\n  if (b === null || typeof b !== \"object\") b = {};\n\n  for (k in b) {\n    if (k in a) {\n      i[k] = value(a[k], b[k]);\n    } else {\n      c[k] = b[k];\n    }\n  }\n\n  return function(t) {\n    for (k in i) c[k] = i[k](t);\n    return c;\n  };\n}\n","import number from \"./number.js\";\n\nvar reA = /[-+]?(?:\\d+\\.?\\d*|\\.?\\d+)(?:[eE][-+]?\\d+)?/g,\n    reB = new RegExp(reA.source, \"g\");\n\nfunction zero(b) {\n  return function() {\n    return b;\n  };\n}\n\nfunction one(b) {\n  return function(t) {\n    return b(t) + \"\";\n  };\n}\n\nexport default function(a, b) {\n  var bi = reA.lastIndex = reB.lastIndex = 0, // scan index for next number in b\n      am, // current match in a\n      bm, // current match in b\n      bs, // string preceding current number in b, if any\n      i = -1, // index in s\n      s = [], // string constants and placeholders\n      q = []; // number interpolators\n\n  // Coerce inputs to strings.\n  a = a + \"\", b = b + \"\";\n\n  // Interpolate pairs of numbers in a & b.\n  while ((am = reA.exec(a))\n      && (bm = reB.exec(b))) {\n    if ((bs = bm.index) > bi) { // a string precedes the next number in b\n      bs = b.slice(bi, bs);\n      if (s[i]) s[i] += bs; // coalesce with previous string\n      else s[++i] = bs;\n    }\n    if ((am = am[0]) === (bm = bm[0])) { // numbers in a & b match\n      if (s[i]) s[i] += bm; // coalesce with previous string\n      else s[++i] = bm;\n    } else { // interpolate non-matching numbers\n      s[++i] = null;\n      q.push({i: i, x: number(am, bm)});\n    }\n    bi = reB.lastIndex;\n  }\n\n  // Add remains of b.\n  if (bi < b.length) {\n    bs = b.slice(bi);\n    if (s[i]) s[i] += bs; // coalesce with previous string\n    else s[++i] = bs;\n  }\n\n  // Special optimization for only a single match.\n  // Otherwise, interpolate each of the numbers and rejoin the string.\n  return s.length < 2 ? (q[0]\n      ? one(q[0].x)\n      : zero(b))\n      : (b = q.length, function(t) {\n          for (var i = 0, o; i < b; ++i) s[(o = q[i]).i] = o.x(t);\n          return s.join(\"\");\n        });\n}\n","var frame = 0, // is an animation frame pending?\n    timeout = 0, // is a timeout pending?\n    interval = 0, // are any timers active?\n    pokeDelay = 1000, // how frequently we check for clock skew\n    taskHead,\n    taskTail,\n    clockLast = 0,\n    clockNow = 0,\n    clockSkew = 0,\n    clock = typeof performance === \"object\" && performance.now ? performance : Date,\n    setFrame = typeof window === \"object\" && window.requestAnimationFrame ? window.requestAnimationFrame.bind(window) : function(f) { setTimeout(f, 17); };\n\nexport function now() {\n  return clockNow || (setFrame(clearNow), clockNow = clock.now() + clockSkew);\n}\n\nfunction clearNow() {\n  clockNow = 0;\n}\n\nexport function Timer() {\n  this._call =\n  this._time =\n  this._next = null;\n}\n\nTimer.prototype = timer.prototype = {\n  constructor: Timer,\n  restart: function(callback, delay, time) {\n    if (typeof callback !== \"function\") throw new TypeError(\"callback is not a function\");\n    time = (time == null ? now() : +time) + (delay == null ? 0 : +delay);\n    if (!this._next && taskTail !== this) {\n      if (taskTail) taskTail._next = this;\n      else taskHead = this;\n      taskTail = this;\n    }\n    this._call = callback;\n    this._time = time;\n    sleep();\n  },\n  stop: function() {\n    if (this._call) {\n      this._call = null;\n      this._time = Infinity;\n      sleep();\n    }\n  }\n};\n\nexport function timer(callback, delay, time) {\n  var t = new Timer;\n  t.restart(callback, delay, time);\n  return t;\n}\n\nexport function timerFlush() {\n  now(); // Get the current time, if not already set.\n  ++frame; // Pretend we’ve set an alarm, if we haven’t already.\n  var t = taskHead, e;\n  while (t) {\n    if ((e = clockNow - t._time) >= 0) t._call.call(null, e);\n    t = t._next;\n  }\n  --frame;\n}\n\nfunction wake() {\n  clockNow = (clockLast = clock.now()) + clockSkew;\n  frame = timeout = 0;\n  try {\n    timerFlush();\n  } finally {\n    frame = 0;\n    nap();\n    clockNow = 0;\n  }\n}\n\nfunction poke() {\n  var now = clock.now(), delay = now - clockLast;\n  if (delay > pokeDelay) clockSkew -= delay, clockLast = now;\n}\n\nfunction nap() {\n  var t0, t1 = taskHead, t2, time = Infinity;\n  while (t1) {\n    if (t1._call) {\n      if (time > t1._time) time = t1._time;\n      t0 = t1, t1 = t1._next;\n    } else {\n      t2 = t1._next, t1._next = null;\n      t1 = t0 ? t0._next = t2 : taskHead = t2;\n    }\n  }\n  taskTail = t0;\n  sleep(time);\n}\n\nfunction sleep(time) {\n  if (frame) return; // Soonest alarm already set, or will be.\n  if (timeout) timeout = clearTimeout(timeout);\n  var delay = time - clockNow; // Strictly less than if we recomputed clockNow.\n  if (delay > 24) {\n    if (time < Infinity) timeout = setTimeout(wake, time - clock.now() - clockSkew);\n    if (interval) interval = clearInterval(interval);\n  } else {\n    if (!interval) clockLast = clock.now(), interval = setInterval(poke, pokeDelay);\n    frame = 1, setFrame(wake);\n  }\n}\n","import {color} from \"d3-color\";\nimport rgb from \"./rgb.js\";\nimport {genericArray} from \"./array.js\";\nimport date from \"./date.js\";\nimport number from \"./number.js\";\nimport object from \"./object.js\";\nimport string from \"./string.js\";\nimport constant from \"./constant.js\";\nimport numberArray, {isNumberArray} from \"./numberArray.js\";\n\nexport default function(a, b) {\n  var t = typeof b, c;\n  return b == null || t === \"boolean\" ? constant(b)\n      : (t === \"number\" ? number\n      : t === \"string\" ? ((c = color(b)) ? (b = c, rgb) : string)\n      : b instanceof color ? rgb\n      : b instanceof Date ? date\n      : isNumberArray(b) ? numberArray\n      : Array.isArray(b) ? genericArray\n      : typeof b.valueOf !== \"function\" && typeof b.toString !== \"function\" || isNaN(b) ? object\n      : number)(a, b);\n}\n","import {event} from \"./selection/on\";\n\nexport default function() {\n  var current = event, source;\n  while (source = current.sourceEvent) current = source;\n  return current;\n}\n","export default function(node, event) {\n  var svg = node.ownerSVGElement || node;\n\n  if (svg.createSVGPoint) {\n    var point = svg.createSVGPoint();\n    point.x = event.clientX, point.y = event.clientY;\n    point = point.matrixTransform(node.getScreenCTM().inverse());\n    return [point.x, point.y];\n  }\n\n  var rect = node.getBoundingClientRect();\n  return [event.clientX - rect.left - node.clientLeft, event.clientY - rect.top - node.clientTop];\n}\n","import sourceEvent from \"./sourceEvent\";\nimport point from \"./point\";\n\nexport default function(node) {\n  var event = sourceEvent();\n  if (event.changedTouches) event = event.changedTouches[0];\n  return point(node, event);\n}\n","import {Timer} from \"./timer.js\";\n\nexport default function(callback, delay, time) {\n  var t = new Timer;\n  delay = delay == null ? 0 : +delay;\n  t.restart(function(elapsed) {\n    t.stop();\n    callback(elapsed + delay);\n  }, delay, time);\n  return t;\n}\n","import {dispatch} from \"d3-dispatch\";\nimport {timer, timeout} from \"d3-timer\";\n\nvar emptyOn = dispatch(\"start\", \"end\", \"cancel\", \"interrupt\");\nvar emptyTween = [];\n\nexport var CREATED = 0;\nexport var SCHEDULED = 1;\nexport var STARTING = 2;\nexport var STARTED = 3;\nexport var RUNNING = 4;\nexport var ENDING = 5;\nexport var ENDED = 6;\n\nexport default function(node, name, id, index, group, timing) {\n  var schedules = node.__transition;\n  if (!schedules) node.__transition = {};\n  else if (id in schedules) return;\n  create(node, id, {\n    name: name,\n    index: index, // For context during callback.\n    group: group, // For context during callback.\n    on: emptyOn,\n    tween: emptyTween,\n    time: timing.time,\n    delay: timing.delay,\n    duration: timing.duration,\n    ease: timing.ease,\n    timer: null,\n    state: CREATED\n  });\n}\n\nexport function init(node, id) {\n  var schedule = get(node, id);\n  if (schedule.state > CREATED) throw new Error(\"too late; already scheduled\");\n  return schedule;\n}\n\nexport function set(node, id) {\n  var schedule = get(node, id);\n  if (schedule.state > STARTED) throw new Error(\"too late; already running\");\n  return schedule;\n}\n\nexport function get(node, id) {\n  var schedule = node.__transition;\n  if (!schedule || !(schedule = schedule[id])) throw new Error(\"transition not found\");\n  return schedule;\n}\n\nfunction create(node, id, self) {\n  var schedules = node.__transition,\n      tween;\n\n  // Initialize the self timer when the transition is created.\n  // Note the actual delay is not known until the first callback!\n  schedules[id] = self;\n  self.timer = timer(schedule, 0, self.time);\n\n  function schedule(elapsed) {\n    self.state = SCHEDULED;\n    self.timer.restart(start, self.delay, self.time);\n\n    // If the elapsed delay is less than our first sleep, start immediately.\n    if (self.delay <= elapsed) start(elapsed - self.delay);\n  }\n\n  function start(elapsed) {\n    var i, j, n, o;\n\n    // If the state is not SCHEDULED, then we previously errored on start.\n    if (self.state !== SCHEDULED) return stop();\n\n    for (i in schedules) {\n      o = schedules[i];\n      if (o.name !== self.name) continue;\n\n      // While this element already has a starting transition during this frame,\n      // defer starting an interrupting transition until that transition has a\n      // chance to tick (and possibly end); see d3/d3-transition#54!\n      if (o.state === STARTED) return timeout(start);\n\n      // Interrupt the active transition, if any.\n      if (o.state === RUNNING) {\n        o.state = ENDED;\n        o.timer.stop();\n        o.on.call(\"interrupt\", node, node.__data__, o.index, o.group);\n        delete schedules[i];\n      }\n\n      // Cancel any pre-empted transitions.\n      else if (+i < id) {\n        o.state = ENDED;\n        o.timer.stop();\n        o.on.call(\"cancel\", node, node.__data__, o.index, o.group);\n        delete schedules[i];\n      }\n    }\n\n    // Defer the first tick to end of the current frame; see d3/d3#1576.\n    // Note the transition may be canceled after start and before the first tick!\n    // Note this must be scheduled before the start event; see d3/d3-transition#16!\n    // Assuming this is successful, subsequent callbacks go straight to tick.\n    timeout(function() {\n      if (self.state === STARTED) {\n        self.state = RUNNING;\n        self.timer.restart(tick, self.delay, self.time);\n        tick(elapsed);\n      }\n    });\n\n    // Dispatch the start event.\n    // Note this must be done before the tween are initialized.\n    self.state = STARTING;\n    self.on.call(\"start\", node, node.__data__, self.index, self.group);\n    if (self.state !== STARTING) return; // interrupted\n    self.state = STARTED;\n\n    // Initialize the tween, deleting null tween.\n    tween = new Array(n = self.tween.length);\n    for (i = 0, j = -1; i < n; ++i) {\n      if (o = self.tween[i].value.call(node, node.__data__, self.index, self.group)) {\n        tween[++j] = o;\n      }\n    }\n    tween.length = j + 1;\n  }\n\n  function tick(elapsed) {\n    var t = elapsed < self.duration ? self.ease.call(null, elapsed / self.duration) : (self.timer.restart(stop), self.state = ENDING, 1),\n        i = -1,\n        n = tween.length;\n\n    while (++i < n) {\n      tween[i].call(node, t);\n    }\n\n    // Dispatch the end event.\n    if (self.state === ENDING) {\n      self.on.call(\"end\", node, node.__data__, self.index, self.group);\n      stop();\n    }\n  }\n\n  function stop() {\n    self.state = ENDED;\n    self.timer.stop();\n    delete schedules[id];\n    for (var i in schedules) return; // eslint-disable-line no-unused-vars\n    delete node.__transition;\n  }\n}\n","import {STARTING, ENDING, ENDED} from \"./transition/schedule.js\";\n\nexport default function(node, name) {\n  var schedules = node.__transition,\n      schedule,\n      active,\n      empty = true,\n      i;\n\n  if (!schedules) return;\n\n  name = name == null ? null : name + \"\";\n\n  for (i in schedules) {\n    if ((schedule = schedules[i]).name !== name) { empty = false; continue; }\n    active = schedule.state > STARTING && schedule.state < ENDING;\n    schedule.state = ENDED;\n    schedule.timer.stop();\n    schedule.on.call(active ? \"interrupt\" : \"cancel\", node, node.__data__, schedule.index, schedule.group);\n    delete schedules[i];\n  }\n\n  if (empty) delete node.__transition;\n}\n","import decompose, {identity} from \"./decompose.js\";\n\nvar cssNode,\n    cssRoot,\n    cssView,\n    svgNode;\n\nexport function parseCss(value) {\n  if (value === \"none\") return identity;\n  if (!cssNode) cssNode = document.createElement(\"DIV\"), cssRoot = document.documentElement, cssView = document.defaultView;\n  cssNode.style.transform = value;\n  value = cssView.getComputedStyle(cssRoot.appendChild(cssNode), null).getPropertyValue(\"transform\");\n  cssRoot.removeChild(cssNode);\n  value = value.slice(7, -1).split(\",\");\n  return decompose(+value[0], +value[1], +value[2], +value[3], +value[4], +value[5]);\n}\n\nexport function parseSvg(value) {\n  if (value == null) return identity;\n  if (!svgNode) svgNode = document.createElementNS(\"http://www.w3.org/2000/svg\", \"g\");\n  svgNode.setAttribute(\"transform\", value);\n  if (!(value = svgNode.transform.baseVal.consolidate())) return identity;\n  value = value.matrix;\n  return decompose(value.a, value.b, value.c, value.d, value.e, value.f);\n}\n","var degrees = 180 / Math.PI;\n\nexport var identity = {\n  translateX: 0,\n  translateY: 0,\n  rotate: 0,\n  skewX: 0,\n  scaleX: 1,\n  scaleY: 1\n};\n\nexport default function(a, b, c, d, e, f) {\n  var scaleX, scaleY, skewX;\n  if (scaleX = Math.sqrt(a * a + b * b)) a /= scaleX, b /= scaleX;\n  if (skewX = a * c + b * d) c -= a * skewX, d -= b * skewX;\n  if (scaleY = Math.sqrt(c * c + d * d)) c /= scaleY, d /= scaleY, skewX /= scaleY;\n  if (a * d < b * c) a = -a, b = -b, skewX = -skewX, scaleX = -scaleX;\n  return {\n    translateX: e,\n    translateY: f,\n    rotate: Math.atan2(b, a) * degrees,\n    skewX: Math.atan(skewX) * degrees,\n    scaleX: scaleX,\n    scaleY: scaleY\n  };\n}\n","import number from \"../number.js\";\nimport {parseCss, parseSvg} from \"./parse.js\";\n\nfunction interpolateTransform(parse, pxComma, pxParen, degParen) {\n\n  function pop(s) {\n    return s.length ? s.pop() + \" \" : \"\";\n  }\n\n  function translate(xa, ya, xb, yb, s, q) {\n    if (xa !== xb || ya !== yb) {\n      var i = s.push(\"translate(\", null, pxComma, null, pxParen);\n      q.push({i: i - 4, x: number(xa, xb)}, {i: i - 2, x: number(ya, yb)});\n    } else if (xb || yb) {\n      s.push(\"translate(\" + xb + pxComma + yb + pxParen);\n    }\n  }\n\n  function rotate(a, b, s, q) {\n    if (a !== b) {\n      if (a - b > 180) b += 360; else if (b - a > 180) a += 360; // shortest path\n      q.push({i: s.push(pop(s) + \"rotate(\", null, degParen) - 2, x: number(a, b)});\n    } else if (b) {\n      s.push(pop(s) + \"rotate(\" + b + degParen);\n    }\n  }\n\n  function skewX(a, b, s, q) {\n    if (a !== b) {\n      q.push({i: s.push(pop(s) + \"skewX(\", null, degParen) - 2, x: number(a, b)});\n    } else if (b) {\n      s.push(pop(s) + \"skewX(\" + b + degParen);\n    }\n  }\n\n  function scale(xa, ya, xb, yb, s, q) {\n    if (xa !== xb || ya !== yb) {\n      var i = s.push(pop(s) + \"scale(\", null, \",\", null, \")\");\n      q.push({i: i - 4, x: number(xa, xb)}, {i: i - 2, x: number(ya, yb)});\n    } else if (xb !== 1 || yb !== 1) {\n      s.push(pop(s) + \"scale(\" + xb + \",\" + yb + \")\");\n    }\n  }\n\n  return function(a, b) {\n    var s = [], // string constants and placeholders\n        q = []; // number interpolators\n    a = parse(a), b = parse(b);\n    translate(a.translateX, a.translateY, b.translateX, b.translateY, s, q);\n    rotate(a.rotate, b.rotate, s, q);\n    skewX(a.skewX, b.skewX, s, q);\n    scale(a.scaleX, a.scaleY, b.scaleX, b.scaleY, s, q);\n    a = b = null; // gc\n    return function(t) {\n      var i = -1, n = q.length, o;\n      while (++i < n) s[(o = q[i]).i] = o.x(t);\n      return s.join(\"\");\n    };\n  };\n}\n\nexport var interpolateTransformCss = interpolateTransform(parseCss, \"px, \", \"px)\", \"deg)\");\nexport var interpolateTransformSvg = interpolateTransform(parseSvg, \", \", \")\", \")\");\n","import {get, set} from \"./schedule.js\";\n\nfunction tweenRemove(id, name) {\n  var tween0, tween1;\n  return function() {\n    var schedule = set(this, id),\n        tween = schedule.tween;\n\n    // If this node shared tween with the previous node,\n    // just assign the updated shared tween and we’re done!\n    // Otherwise, copy-on-write.\n    if (tween !== tween0) {\n      tween1 = tween0 = tween;\n      for (var i = 0, n = tween1.length; i < n; ++i) {\n        if (tween1[i].name === name) {\n          tween1 = tween1.slice();\n          tween1.splice(i, 1);\n          break;\n        }\n      }\n    }\n\n    schedule.tween = tween1;\n  };\n}\n\nfunction tweenFunction(id, name, value) {\n  var tween0, tween1;\n  if (typeof value !== \"function\") throw new Error;\n  return function() {\n    var schedule = set(this, id),\n        tween = schedule.tween;\n\n    // If this node shared tween with the previous node,\n    // just assign the updated shared tween and we’re done!\n    // Otherwise, copy-on-write.\n    if (tween !== tween0) {\n      tween1 = (tween0 = tween).slice();\n      for (var t = {name: name, value: value}, i = 0, n = tween1.length; i < n; ++i) {\n        if (tween1[i].name === name) {\n          tween1[i] = t;\n          break;\n        }\n      }\n      if (i === n) tween1.push(t);\n    }\n\n    schedule.tween = tween1;\n  };\n}\n\nexport default function(name, value) {\n  var id = this._id;\n\n  name += \"\";\n\n  if (arguments.length < 2) {\n    var tween = get(this.node(), id).tween;\n    for (var i = 0, n = tween.length, t; i < n; ++i) {\n      if ((t = tween[i]).name === name) {\n        return t.value;\n      }\n    }\n    return null;\n  }\n\n  return this.each((value == null ? tweenRemove : tweenFunction)(id, name, value));\n}\n\nexport function tweenValue(transition, name, value) {\n  var id = transition._id;\n\n  transition.each(function() {\n    var schedule = set(this, id);\n    (schedule.value || (schedule.value = {}))[name] = value.apply(this, arguments);\n  });\n\n  return function(node) {\n    return get(node, id).value[name];\n  };\n}\n","import {color} from \"d3-color\";\nimport {interpolateNumber, interpolateRgb, interpolateString} from \"d3-interpolate\";\n\nexport default function(a, b) {\n  var c;\n  return (typeof b === \"number\" ? interpolateNumber\n      : b instanceof color ? interpolateRgb\n      : (c = color(b)) ? (b = c, interpolateRgb)\n      : interpolateString)(a, b);\n}\n","import {interpolateTransformSvg as interpolateTransform} from \"d3-interpolate\";\nimport {namespace} from \"d3-selection\";\nimport {tweenValue} from \"./tween.js\";\nimport interpolate from \"./interpolate.js\";\n\nfunction attrRemove(name) {\n  return function() {\n    this.removeAttribute(name);\n  };\n}\n\nfunction attrRemoveNS(fullname) {\n  return function() {\n    this.removeAttributeNS(fullname.space, fullname.local);\n  };\n}\n\nfunction attrConstant(name, interpolate, value1) {\n  var string00,\n      string1 = value1 + \"\",\n      interpolate0;\n  return function() {\n    var string0 = this.getAttribute(name);\n    return string0 === string1 ? null\n        : string0 === string00 ? interpolate0\n        : interpolate0 = interpolate(string00 = string0, value1);\n  };\n}\n\nfunction attrConstantNS(fullname, interpolate, value1) {\n  var string00,\n      string1 = value1 + \"\",\n      interpolate0;\n  return function() {\n    var string0 = this.getAttributeNS(fullname.space, fullname.local);\n    return string0 === string1 ? null\n        : string0 === string00 ? interpolate0\n        : interpolate0 = interpolate(string00 = string0, value1);\n  };\n}\n\nfunction attrFunction(name, interpolate, value) {\n  var string00,\n      string10,\n      interpolate0;\n  return function() {\n    var string0, value1 = value(this), string1;\n    if (value1 == null) return void this.removeAttribute(name);\n    string0 = this.getAttribute(name);\n    string1 = value1 + \"\";\n    return string0 === string1 ? null\n        : string0 === string00 && string1 === string10 ? interpolate0\n        : (string10 = string1, interpolate0 = interpolate(string00 = string0, value1));\n  };\n}\n\nfunction attrFunctionNS(fullname, interpolate, value) {\n  var string00,\n      string10,\n      interpolate0;\n  return function() {\n    var string0, value1 = value(this), string1;\n    if (value1 == null) return void this.removeAttributeNS(fullname.space, fullname.local);\n    string0 = this.getAttributeNS(fullname.space, fullname.local);\n    string1 = value1 + \"\";\n    return string0 === string1 ? null\n        : string0 === string00 && string1 === string10 ? interpolate0\n        : (string10 = string1, interpolate0 = interpolate(string00 = string0, value1));\n  };\n}\n\nexport default function(name, value) {\n  var fullname = namespace(name), i = fullname === \"transform\" ? interpolateTransform : interpolate;\n  return this.attrTween(name, typeof value === \"function\"\n      ? (fullname.local ? attrFunctionNS : attrFunction)(fullname, i, tweenValue(this, \"attr.\" + name, value))\n      : value == null ? (fullname.local ? attrRemoveNS : attrRemove)(fullname)\n      : (fullname.local ? attrConstantNS : attrConstant)(fullname, i, value));\n}\n","import {namespace} from \"d3-selection\";\n\nfunction attrInterpolate(name, i) {\n  return function(t) {\n    this.setAttribute(name, i.call(this, t));\n  };\n}\n\nfunction attrInterpolateNS(fullname, i) {\n  return function(t) {\n    this.setAttributeNS(fullname.space, fullname.local, i.call(this, t));\n  };\n}\n\nfunction attrTweenNS(fullname, value) {\n  var t0, i0;\n  function tween() {\n    var i = value.apply(this, arguments);\n    if (i !== i0) t0 = (i0 = i) && attrInterpolateNS(fullname, i);\n    return t0;\n  }\n  tween._value = value;\n  return tween;\n}\n\nfunction attrTween(name, value) {\n  var t0, i0;\n  function tween() {\n    var i = value.apply(this, arguments);\n    if (i !== i0) t0 = (i0 = i) && attrInterpolate(name, i);\n    return t0;\n  }\n  tween._value = value;\n  return tween;\n}\n\nexport default function(name, value) {\n  var key = \"attr.\" + name;\n  if (arguments.length < 2) return (key = this.tween(key)) && key._value;\n  if (value == null) return this.tween(key, null);\n  if (typeof value !== \"function\") throw new Error;\n  var fullname = namespace(name);\n  return this.tween(key, (fullname.local ? attrTweenNS : attrTween)(fullname, value));\n}\n","import {get, init} from \"./schedule.js\";\n\nfunction delayFunction(id, value) {\n  return function() {\n    init(this, id).delay = +value.apply(this, arguments);\n  };\n}\n\nfunction delayConstant(id, value) {\n  return value = +value, function() {\n    init(this, id).delay = value;\n  };\n}\n\nexport default function(value) {\n  var id = this._id;\n\n  return arguments.length\n      ? this.each((typeof value === \"function\"\n          ? delayFunction\n          : delayConstant)(id, value))\n      : get(this.node(), id).delay;\n}\n","import {get, set} from \"./schedule.js\";\n\nfunction durationFunction(id, value) {\n  return function() {\n    set(this, id).duration = +value.apply(this, arguments);\n  };\n}\n\nfunction durationConstant(id, value) {\n  return value = +value, function() {\n    set(this, id).duration = value;\n  };\n}\n\nexport default function(value) {\n  var id = this._id;\n\n  return arguments.length\n      ? this.each((typeof value === \"function\"\n          ? durationFunction\n          : durationConstant)(id, value))\n      : get(this.node(), id).duration;\n}\n","import {get, set} from \"./schedule.js\";\n\nfunction easeConstant(id, value) {\n  if (typeof value !== \"function\") throw new Error;\n  return function() {\n    set(this, id).ease = value;\n  };\n}\n\nexport default function(value) {\n  var id = this._id;\n\n  return arguments.length\n      ? this.each(easeConstant(id, value))\n      : get(this.node(), id).ease;\n}\n","import {get, set, init} from \"./schedule.js\";\n\nfunction start(name) {\n  return (name + \"\").trim().split(/^|\\s+/).every(function(t) {\n    var i = t.indexOf(\".\");\n    if (i >= 0) t = t.slice(0, i);\n    return !t || t === \"start\";\n  });\n}\n\nfunction onFunction(id, name, listener) {\n  var on0, on1, sit = start(name) ? init : set;\n  return function() {\n    var schedule = sit(this, id),\n        on = schedule.on;\n\n    // If this node shared a dispatch with the previous node,\n    // just assign the updated shared dispatch and we’re done!\n    // Otherwise, copy-on-write.\n    if (on !== on0) (on1 = (on0 = on).copy()).on(name, listener);\n\n    schedule.on = on1;\n  };\n}\n\nexport default function(name, listener) {\n  var id = this._id;\n\n  return arguments.length < 2\n      ? get(this.node(), id).on.on(name)\n      : this.each(onFunction(id, name, listener));\n}\n","function removeFunction(id) {\n  return function() {\n    var parent = this.parentNode;\n    for (var i in this.__transition) if (+i !== id) return;\n    if (parent) parent.removeChild(this);\n  };\n}\n\nexport default function() {\n  return this.on(\"end.remove\", removeFunction(this._id));\n}\n","import {selection} from \"d3-selection\";\n\nvar Selection = selection.prototype.constructor;\n\nexport default function() {\n  return new Selection(this._groups, this._parents);\n}\n","import {interpolateTransformCss as interpolateTransform} from \"d3-interpolate\";\nimport {style} from \"d3-selection\";\nimport {set} from \"./schedule.js\";\nimport {tweenValue} from \"./tween.js\";\nimport interpolate from \"./interpolate.js\";\n\nfunction styleNull(name, interpolate) {\n  var string00,\n      string10,\n      interpolate0;\n  return function() {\n    var string0 = style(this, name),\n        string1 = (this.style.removeProperty(name), style(this, name));\n    return string0 === string1 ? null\n        : string0 === string00 && string1 === string10 ? interpolate0\n        : interpolate0 = interpolate(string00 = string0, string10 = string1);\n  };\n}\n\nfunction styleRemove(name) {\n  return function() {\n    this.style.removeProperty(name);\n  };\n}\n\nfunction styleConstant(name, interpolate, value1) {\n  var string00,\n      string1 = value1 + \"\",\n      interpolate0;\n  return function() {\n    var string0 = style(this, name);\n    return string0 === string1 ? null\n        : string0 === string00 ? interpolate0\n        : interpolate0 = interpolate(string00 = string0, value1);\n  };\n}\n\nfunction styleFunction(name, interpolate, value) {\n  var string00,\n      string10,\n      interpolate0;\n  return function() {\n    var string0 = style(this, name),\n        value1 = value(this),\n        string1 = value1 + \"\";\n    if (value1 == null) string1 = value1 = (this.style.removeProperty(name), style(this, name));\n    return string0 === string1 ? null\n        : string0 === string00 && string1 === string10 ? interpolate0\n        : (string10 = string1, interpolate0 = interpolate(string00 = string0, value1));\n  };\n}\n\nfunction styleMaybeRemove(id, name) {\n  var on0, on1, listener0, key = \"style.\" + name, event = \"end.\" + key, remove;\n  return function() {\n    var schedule = set(this, id),\n        on = schedule.on,\n        listener = schedule.value[key] == null ? remove || (remove = styleRemove(name)) : undefined;\n\n    // If this node shared a dispatch with the previous node,\n    // just assign the updated shared dispatch and we’re done!\n    // Otherwise, copy-on-write.\n    if (on !== on0 || listener0 !== listener) (on1 = (on0 = on).copy()).on(event, listener0 = listener);\n\n    schedule.on = on1;\n  };\n}\n\nexport default function(name, value, priority) {\n  var i = (name += \"\") === \"transform\" ? interpolateTransform : interpolate;\n  return value == null ? this\n      .styleTween(name, styleNull(name, i))\n      .on(\"end.style.\" + name, styleRemove(name))\n    : typeof value === \"function\" ? this\n      .styleTween(name, styleFunction(name, i, tweenValue(this, \"style.\" + name, value)))\n      .each(styleMaybeRemove(this._id, name))\n    : this\n      .styleTween(name, styleConstant(name, i, value), priority)\n      .on(\"end.style.\" + name, null);\n}\n","function styleInterpolate(name, i, priority) {\n  return function(t) {\n    this.style.setProperty(name, i.call(this, t), priority);\n  };\n}\n\nfunction styleTween(name, value, priority) {\n  var t, i0;\n  function tween() {\n    var i = value.apply(this, arguments);\n    if (i !== i0) t = (i0 = i) && styleInterpolate(name, i, priority);\n    return t;\n  }\n  tween._value = value;\n  return tween;\n}\n\nexport default function(name, value, priority) {\n  var key = \"style.\" + (name += \"\");\n  if (arguments.length < 2) return (key = this.tween(key)) && key._value;\n  if (value == null) return this.tween(key, null);\n  if (typeof value !== \"function\") throw new Error;\n  return this.tween(key, styleTween(name, value, priority == null ? \"\" : priority));\n}\n","function textInterpolate(i) {\n  return function(t) {\n    this.textContent = i.call(this, t);\n  };\n}\n\nfunction textTween(value) {\n  var t0, i0;\n  function tween() {\n    var i = value.apply(this, arguments);\n    if (i !== i0) t0 = (i0 = i) && textInterpolate(i);\n    return t0;\n  }\n  tween._value = value;\n  return tween;\n}\n\nexport default function(value) {\n  var key = \"text\";\n  if (arguments.length < 1) return (key = this.tween(key)) && key._value;\n  if (value == null) return this.tween(key, null);\n  if (typeof value !== \"function\") throw new Error;\n  return this.tween(key, textTween(value));\n}\n","import {selection} from \"d3-selection\";\nimport transition_attr from \"./attr.js\";\nimport transition_attrTween from \"./attrTween.js\";\nimport transition_delay from \"./delay.js\";\nimport transition_duration from \"./duration.js\";\nimport transition_ease from \"./ease.js\";\nimport transition_filter from \"./filter.js\";\nimport transition_merge from \"./merge.js\";\nimport transition_on from \"./on.js\";\nimport transition_remove from \"./remove.js\";\nimport transition_select from \"./select.js\";\nimport transition_selectAll from \"./selectAll.js\";\nimport transition_selection from \"./selection.js\";\nimport transition_style from \"./style.js\";\nimport transition_styleTween from \"./styleTween.js\";\nimport transition_text from \"./text.js\";\nimport transition_textTween from \"./textTween.js\";\nimport transition_transition from \"./transition.js\";\nimport transition_tween from \"./tween.js\";\nimport transition_end from \"./end.js\";\n\nvar id = 0;\n\nexport function Transition(groups, parents, name, id) {\n  this._groups = groups;\n  this._parents = parents;\n  this._name = name;\n  this._id = id;\n}\n\nexport default function transition(name) {\n  return selection().transition(name);\n}\n\nexport function newId() {\n  return ++id;\n}\n\nvar selection_prototype = selection.prototype;\n\nTransition.prototype = transition.prototype = {\n  constructor: Transition,\n  select: transition_select,\n  selectAll: transition_selectAll,\n  filter: transition_filter,\n  merge: transition_merge,\n  selection: transition_selection,\n  transition: transition_transition,\n  call: selection_prototype.call,\n  nodes: selection_prototype.nodes,\n  node: selection_prototype.node,\n  size: selection_prototype.size,\n  empty: selection_prototype.empty,\n  each: selection_prototype.each,\n  on: transition_on,\n  attr: transition_attr,\n  attrTween: transition_attrTween,\n  style: transition_style,\n  styleTween: transition_styleTween,\n  text: transition_text,\n  textTween: transition_textTween,\n  remove: transition_remove,\n  tween: transition_tween,\n  delay: transition_delay,\n  duration: transition_duration,\n  ease: transition_ease,\n  end: transition_end\n};\n","import {selector} from \"d3-selection\";\nimport {Transition} from \"./index.js\";\nimport schedule, {get} from \"./schedule.js\";\n\nexport default function(select) {\n  var name = this._name,\n      id = this._id;\n\n  if (typeof select !== \"function\") select = selector(select);\n\n  for (var groups = this._groups, m = groups.length, subgroups = new Array(m), j = 0; j < m; ++j) {\n    for (var group = groups[j], n = group.length, subgroup = subgroups[j] = new Array(n), node, subnode, i = 0; i < n; ++i) {\n      if ((node = group[i]) && (subnode = select.call(node, node.__data__, i, group))) {\n        if (\"__data__\" in node) subnode.__data__ = node.__data__;\n        subgroup[i] = subnode;\n        schedule(subgroup[i], name, id, i, subgroup, get(node, id));\n      }\n    }\n  }\n\n  return new Transition(subgroups, this._parents, name, id);\n}\n","import {selectorAll} from \"d3-selection\";\nimport {Transition} from \"./index.js\";\nimport schedule, {get} from \"./schedule.js\";\n\nexport default function(select) {\n  var name = this._name,\n      id = this._id;\n\n  if (typeof select !== \"function\") select = selectorAll(select);\n\n  for (var groups = this._groups, m = groups.length, subgroups = [], parents = [], j = 0; j < m; ++j) {\n    for (var group = groups[j], n = group.length, node, i = 0; i < n; ++i) {\n      if (node = group[i]) {\n        for (var children = select.call(node, node.__data__, i, group), child, inherit = get(node, id), k = 0, l = children.length; k < l; ++k) {\n          if (child = children[k]) {\n            schedule(child, name, id, k, children, inherit);\n          }\n        }\n        subgroups.push(children);\n        parents.push(node);\n      }\n    }\n  }\n\n  return new Transition(subgroups, parents, name, id);\n}\n","import {matcher} from \"d3-selection\";\nimport {Transition} from \"./index.js\";\n\nexport default function(match) {\n  if (typeof match !== \"function\") match = matcher(match);\n\n  for (var groups = this._groups, m = groups.length, subgroups = new Array(m), j = 0; j < m; ++j) {\n    for (var group = groups[j], n = group.length, subgroup = subgroups[j] = [], node, i = 0; i < n; ++i) {\n      if ((node = group[i]) && match.call(node, node.__data__, i, group)) {\n        subgroup.push(node);\n      }\n    }\n  }\n\n  return new Transition(subgroups, this._parents, this._name, this._id);\n}\n","import {Transition} from \"./index.js\";\n\nexport default function(transition) {\n  if (transition._id !== this._id) throw new Error;\n\n  for (var groups0 = this._groups, groups1 = transition._groups, m0 = groups0.length, m1 = groups1.length, m = Math.min(m0, m1), merges = new Array(m0), j = 0; j < m; ++j) {\n    for (var group0 = groups0[j], group1 = groups1[j], n = group0.length, merge = merges[j] = new Array(n), node, i = 0; i < n; ++i) {\n      if (node = group0[i] || group1[i]) {\n        merge[i] = node;\n      }\n    }\n  }\n\n  for (; j < m0; ++j) {\n    merges[j] = groups0[j];\n  }\n\n  return new Transition(merges, this._parents, this._name, this._id);\n}\n","import {Transition, newId} from \"./index.js\";\nimport schedule, {get} from \"./schedule.js\";\n\nexport default function() {\n  var name = this._name,\n      id0 = this._id,\n      id1 = newId();\n\n  for (var groups = this._groups, m = groups.length, j = 0; j < m; ++j) {\n    for (var group = groups[j], n = group.length, node, i = 0; i < n; ++i) {\n      if (node = group[i]) {\n        var inherit = get(node, id0);\n        schedule(node, name, id1, i, group, {\n          time: inherit.time + inherit.delay + inherit.duration,\n          delay: 0,\n          duration: inherit.duration,\n          ease: inherit.ease\n        });\n      }\n    }\n  }\n\n  return new Transition(groups, this._parents, name, id1);\n}\n","import {tweenValue} from \"./tween.js\";\n\nfunction textConstant(value) {\n  return function() {\n    this.textContent = value;\n  };\n}\n\nfunction textFunction(value) {\n  return function() {\n    var value1 = value(this);\n    this.textContent = value1 == null ? \"\" : value1;\n  };\n}\n\nexport default function(value) {\n  return this.tween(\"text\", typeof value === \"function\"\n      ? textFunction(tweenValue(this, \"text\", value))\n      : textConstant(value == null ? \"\" : value + \"\"));\n}\n","import {set} from \"./schedule.js\";\n\nexport default function() {\n  var on0, on1, that = this, id = that._id, size = that.size();\n  return new Promise(function(resolve, reject) {\n    var cancel = {value: reject},\n        end = {value: function() { if (--size === 0) resolve(); }};\n\n    that.each(function() {\n      var schedule = set(this, id),\n          on = schedule.on;\n\n      // If this node shared a dispatch with the previous node,\n      // just assign the updated shared dispatch and we’re done!\n      // Otherwise, copy-on-write.\n      if (on !== on0) {\n        on1 = (on0 = on).copy();\n        on1._.cancel.push(cancel);\n        on1._.interrupt.push(cancel);\n        on1._.end.push(end);\n      }\n\n      schedule.on = on1;\n    });\n  });\n}\n","import {Transition, newId} from \"../transition/index.js\";\nimport schedule from \"../transition/schedule.js\";\nimport {easeCubicInOut} from \"d3-ease\";\nimport {now} from \"d3-timer\";\n\nvar defaultTiming = {\n  time: null, // Set on use.\n  delay: 0,\n  duration: 250,\n  ease: easeCubicInOut\n};\n\nfunction inherit(node, id) {\n  var timing;\n  while (!(timing = node.__transition) || !(timing = timing[id])) {\n    if (!(node = node.parentNode)) {\n      return defaultTiming.time = now(), defaultTiming;\n    }\n  }\n  return timing;\n}\n\nexport default function(name) {\n  var id,\n      timing;\n\n  if (name instanceof Transition) {\n    id = name._id, name = name._name;\n  } else {\n    id = newId(), (timing = defaultTiming).time = now(), name = name == null ? null : name + \"\";\n  }\n\n  for (var groups = this._groups, m = groups.length, j = 0; j < m; ++j) {\n    for (var group = groups[j], n = group.length, node, i = 0; i < n; ++i) {\n      if (node = group[i]) {\n        schedule(node, name, id, i, group, timing || inherit(node, id));\n      }\n    }\n  }\n\n  return new Transition(groups, this._parents, name, id);\n}\n","export function cubicIn(t) {\n  return t * t * t;\n}\n\nexport function cubicOut(t) {\n  return --t * t * t + 1;\n}\n\nexport function cubicInOut(t) {\n  return ((t *= 2) <= 1 ? t * t * t : (t -= 2) * t * t + 2) / 2;\n}\n","import {selection} from \"d3-selection\";\nimport selection_interrupt from \"./interrupt.js\";\nimport selection_transition from \"./transition.js\";\n\nselection.prototype.interrupt = selection_interrupt;\nselection.prototype.transition = selection_transition;\n","import interrupt from \"../interrupt.js\";\n\nexport default function(name) {\n  return this.each(function() {\n    interrupt(this, name);\n  });\n}\n","import {Transition} from \"./transition/index.js\";\nimport {SCHEDULED} from \"./transition/schedule.js\";\n\nvar root = [null];\n\nexport default function(node, name) {\n  var schedules = node.__transition,\n      schedule,\n      i;\n\n  if (schedules) {\n    name = name == null ? null : name + \"\";\n    for (i in schedules) {\n      if ((schedule = schedules[i]).state > SCHEDULED && schedule.name === name) {\n        return new Transition([[node]], root, name, +i);\n      }\n    }\n  }\n\n  return null;\n}\n","export default function(x) {\n  return function() {\n    return x;\n  };\n}\n","export default function(target, type, selection) {\n  this.target = target;\n  this.type = type;\n  this.selection = selection;\n}\n","import {event} from \"d3-selection\";\n\nexport function nopropagation() {\n  event.stopImmediatePropagation();\n}\n\nexport default function() {\n  event.preventDefault();\n  event.stopImmediatePropagation();\n}\n","import {dispatch} from \"d3-dispatch\";\nimport {dragDisable, dragEnable} from \"d3-drag\";\nimport {interpolate} from \"d3-interpolate\";\nimport {customEvent, event, touch, mouse, select} from \"d3-selection\";\nimport {interrupt} from \"d3-transition\";\nimport constant from \"./constant.js\";\nimport BrushEvent from \"./event.js\";\nimport noevent, {nopropagation} from \"./noevent.js\";\n\nvar MODE_DRAG = {name: \"drag\"},\n    MODE_SPACE = {name: \"space\"},\n    MODE_HANDLE = {name: \"handle\"},\n    MODE_CENTER = {name: \"center\"};\n\nfunction number1(e) {\n  return [+e[0], +e[1]];\n}\n\nfunction number2(e) {\n  return [number1(e[0]), number1(e[1])];\n}\n\nfunction toucher(identifier) {\n  return function(target) {\n    return touch(target, event.touches, identifier);\n  };\n}\n\nvar X = {\n  name: \"x\",\n  handles: [\"w\", \"e\"].map(type),\n  input: function(x, e) { return x == null ? null : [[+x[0], e[0][1]], [+x[1], e[1][1]]]; },\n  output: function(xy) { return xy && [xy[0][0], xy[1][0]]; }\n};\n\nvar Y = {\n  name: \"y\",\n  handles: [\"n\", \"s\"].map(type),\n  input: function(y, e) { return y == null ? null : [[e[0][0], +y[0]], [e[1][0], +y[1]]]; },\n  output: function(xy) { return xy && [xy[0][1], xy[1][1]]; }\n};\n\nvar XY = {\n  name: \"xy\",\n  handles: [\"n\", \"w\", \"e\", \"s\", \"nw\", \"ne\", \"sw\", \"se\"].map(type),\n  input: function(xy) { return xy == null ? null : number2(xy); },\n  output: function(xy) { return xy; }\n};\n\nvar cursors = {\n  overlay: \"crosshair\",\n  selection: \"move\",\n  n: \"ns-resize\",\n  e: \"ew-resize\",\n  s: \"ns-resize\",\n  w: \"ew-resize\",\n  nw: \"nwse-resize\",\n  ne: \"nesw-resize\",\n  se: \"nwse-resize\",\n  sw: \"nesw-resize\"\n};\n\nvar flipX = {\n  e: \"w\",\n  w: \"e\",\n  nw: \"ne\",\n  ne: \"nw\",\n  se: \"sw\",\n  sw: \"se\"\n};\n\nvar flipY = {\n  n: \"s\",\n  s: \"n\",\n  nw: \"sw\",\n  ne: \"se\",\n  se: \"ne\",\n  sw: \"nw\"\n};\n\nvar signsX = {\n  overlay: +1,\n  selection: +1,\n  n: null,\n  e: +1,\n  s: null,\n  w: -1,\n  nw: -1,\n  ne: +1,\n  se: +1,\n  sw: -1\n};\n\nvar signsY = {\n  overlay: +1,\n  selection: +1,\n  n: -1,\n  e: null,\n  s: +1,\n  w: null,\n  nw: -1,\n  ne: -1,\n  se: +1,\n  sw: +1\n};\n\nfunction type(t) {\n  return {type: t};\n}\n\n// Ignore right-click, since that should open the context menu.\nfunction defaultFilter() {\n  return !event.ctrlKey && !event.button;\n}\n\nfunction defaultExtent() {\n  var svg = this.ownerSVGElement || this;\n  if (svg.hasAttribute(\"viewBox\")) {\n    svg = svg.viewBox.baseVal;\n    return [[svg.x, svg.y], [svg.x + svg.width, svg.y + svg.height]];\n  }\n  return [[0, 0], [svg.width.baseVal.value, svg.height.baseVal.value]];\n}\n\nfunction defaultTouchable() {\n  return navigator.maxTouchPoints || (\"ontouchstart\" in this);\n}\n\n// Like d3.local, but with the name “__brush” rather than auto-generated.\nfunction local(node) {\n  while (!node.__brush) if (!(node = node.parentNode)) return;\n  return node.__brush;\n}\n\nfunction empty(extent) {\n  return extent[0][0] === extent[1][0]\n      || extent[0][1] === extent[1][1];\n}\n\nexport function brushSelection(node) {\n  var state = node.__brush;\n  return state ? state.dim.output(state.selection) : null;\n}\n\nexport function brushX() {\n  return brush(X);\n}\n\nexport function brushY() {\n  return brush(Y);\n}\n\nexport default function() {\n  return brush(XY);\n}\n\nfunction brush(dim) {\n  var extent = defaultExtent,\n      filter = defaultFilter,\n      touchable = defaultTouchable,\n      keys = true,\n      listeners = dispatch(\"start\", \"brush\", \"end\"),\n      handleSize = 6,\n      touchending;\n\n  function brush(group) {\n    var overlay = group\n        .property(\"__brush\", initialize)\n      .selectAll(\".overlay\")\n      .data([type(\"overlay\")]);\n\n    overlay.enter().append(\"rect\")\n        .attr(\"class\", \"overlay\")\n        .attr(\"pointer-events\", \"all\")\n        .attr(\"cursor\", cursors.overlay)\n      .merge(overlay)\n        .each(function() {\n          var extent = local(this).extent;\n          select(this)\n              .attr(\"x\", extent[0][0])\n              .attr(\"y\", extent[0][1])\n              .attr(\"width\", extent[1][0] - extent[0][0])\n              .attr(\"height\", extent[1][1] - extent[0][1]);\n        });\n\n    group.selectAll(\".selection\")\n      .data([type(\"selection\")])\n      .enter().append(\"rect\")\n        .attr(\"class\", \"selection\")\n        .attr(\"cursor\", cursors.selection)\n        .attr(\"fill\", \"#777\")\n        .attr(\"fill-opacity\", 0.3)\n        .attr(\"stroke\", \"#fff\")\n        .attr(\"shape-rendering\", \"crispEdges\");\n\n    var handle = group.selectAll(\".handle\")\n      .data(dim.handles, function(d) { return d.type; });\n\n    handle.exit().remove();\n\n    handle.enter().append(\"rect\")\n        .attr(\"class\", function(d) { return \"handle handle--\" + d.type; })\n        .attr(\"cursor\", function(d) { return cursors[d.type]; });\n\n    group\n        .each(redraw)\n        .attr(\"fill\", \"none\")\n        .attr(\"pointer-events\", \"all\")\n        .on(\"mousedown.brush\", started)\n      .filter(touchable)\n        .on(\"touchstart.brush\", started)\n        .on(\"touchmove.brush\", touchmoved)\n        .on(\"touchend.brush touchcancel.brush\", touchended)\n        .style(\"touch-action\", \"none\")\n        .style(\"-webkit-tap-highlight-color\", \"rgba(0,0,0,0)\");\n  }\n\n  brush.move = function(group, selection) {\n    if (group.selection) {\n      group\n          .on(\"start.brush\", function() { emitter(this, arguments).beforestart().start(); })\n          .on(\"interrupt.brush end.brush\", function() { emitter(this, arguments).end(); })\n          .tween(\"brush\", function() {\n            var that = this,\n                state = that.__brush,\n                emit = emitter(that, arguments),\n                selection0 = state.selection,\n                selection1 = dim.input(typeof selection === \"function\" ? selection.apply(this, arguments) : selection, state.extent),\n                i = interpolate(selection0, selection1);\n\n            function tween(t) {\n              state.selection = t === 1 && selection1 === null ? null : i(t);\n              redraw.call(that);\n              emit.brush();\n            }\n\n            return selection0 !== null && selection1 !== null ? tween : tween(1);\n          });\n    } else {\n      group\n          .each(function() {\n            var that = this,\n                args = arguments,\n                state = that.__brush,\n                selection1 = dim.input(typeof selection === \"function\" ? selection.apply(that, args) : selection, state.extent),\n                emit = emitter(that, args).beforestart();\n\n            interrupt(that);\n            state.selection = selection1 === null ? null : selection1;\n            redraw.call(that);\n            emit.start().brush().end();\n          });\n    }\n  };\n\n  brush.clear = function(group) {\n    brush.move(group, null);\n  };\n\n  function redraw() {\n    var group = select(this),\n        selection = local(this).selection;\n\n    if (selection) {\n      group.selectAll(\".selection\")\n          .style(\"display\", null)\n          .attr(\"x\", selection[0][0])\n          .attr(\"y\", selection[0][1])\n          .attr(\"width\", selection[1][0] - selection[0][0])\n          .attr(\"height\", selection[1][1] - selection[0][1]);\n\n      group.selectAll(\".handle\")\n          .style(\"display\", null)\n          .attr(\"x\", function(d) { return d.type[d.type.length - 1] === \"e\" ? selection[1][0] - handleSize / 2 : selection[0][0] - handleSize / 2; })\n          .attr(\"y\", function(d) { return d.type[0] === \"s\" ? selection[1][1] - handleSize / 2 : selection[0][1] - handleSize / 2; })\n          .attr(\"width\", function(d) { return d.type === \"n\" || d.type === \"s\" ? selection[1][0] - selection[0][0] + handleSize : handleSize; })\n          .attr(\"height\", function(d) { return d.type === \"e\" || d.type === \"w\" ? selection[1][1] - selection[0][1] + handleSize : handleSize; });\n    }\n\n    else {\n      group.selectAll(\".selection,.handle\")\n          .style(\"display\", \"none\")\n          .attr(\"x\", null)\n          .attr(\"y\", null)\n          .attr(\"width\", null)\n          .attr(\"height\", null);\n    }\n  }\n\n  function emitter(that, args, clean) {\n    return (!clean && that.__brush.emitter) || new Emitter(that, args);\n  }\n\n  function Emitter(that, args) {\n    this.that = that;\n    this.args = args;\n    this.state = that.__brush;\n    this.active = 0;\n  }\n\n  Emitter.prototype = {\n    beforestart: function() {\n      if (++this.active === 1) this.state.emitter = this, this.starting = true;\n      return this;\n    },\n    start: function() {\n      if (this.starting) this.starting = false, this.emit(\"start\");\n      else this.emit(\"brush\");\n      return this;\n    },\n    brush: function() {\n      this.emit(\"brush\");\n      return this;\n    },\n    end: function() {\n      if (--this.active === 0) delete this.state.emitter, this.emit(\"end\");\n      return this;\n    },\n    emit: function(type) {\n      customEvent(new BrushEvent(brush, type, dim.output(this.state.selection)), listeners.apply, listeners, [type, this.that, this.args]);\n    }\n  };\n\n  function started() {\n    if (touchending && !event.touches) return;\n    if (!filter.apply(this, arguments)) return;\n\n    var that = this,\n        type = event.target.__data__.type,\n        mode = (keys && event.metaKey ? type = \"overlay\" : type) === \"selection\" ? MODE_DRAG : (keys && event.altKey ? MODE_CENTER : MODE_HANDLE),\n        signX = dim === Y ? null : signsX[type],\n        signY = dim === X ? null : signsY[type],\n        state = local(that),\n        extent = state.extent,\n        selection = state.selection,\n        W = extent[0][0], w0, w1,\n        N = extent[0][1], n0, n1,\n        E = extent[1][0], e0, e1,\n        S = extent[1][1], s0, s1,\n        dx = 0,\n        dy = 0,\n        moving,\n        shifting = signX && signY && keys && event.shiftKey,\n        lockX,\n        lockY,\n        pointer = event.touches ? toucher(event.changedTouches[0].identifier) : mouse,\n        point0 = pointer(that),\n        point = point0,\n        emit = emitter(that, arguments, true).beforestart();\n\n    if (type === \"overlay\") {\n      if (selection) moving = true;\n      state.selection = selection = [\n        [w0 = dim === Y ? W : point0[0], n0 = dim === X ? N : point0[1]],\n        [e0 = dim === Y ? E : w0, s0 = dim === X ? S : n0]\n      ];\n    } else {\n      w0 = selection[0][0];\n      n0 = selection[0][1];\n      e0 = selection[1][0];\n      s0 = selection[1][1];\n    }\n\n    w1 = w0;\n    n1 = n0;\n    e1 = e0;\n    s1 = s0;\n\n    var group = select(that)\n        .attr(\"pointer-events\", \"none\");\n\n    var overlay = group.selectAll(\".overlay\")\n        .attr(\"cursor\", cursors[type]);\n\n    if (event.touches) {\n      emit.moved = moved;\n      emit.ended = ended;\n    } else {\n      var view = select(event.view)\n          .on(\"mousemove.brush\", moved, true)\n          .on(\"mouseup.brush\", ended, true);\n      if (keys) view\n          .on(\"keydown.brush\", keydowned, true)\n          .on(\"keyup.brush\", keyupped, true)\n\n      dragDisable(event.view);\n    }\n\n    nopropagation();\n    interrupt(that);\n    redraw.call(that);\n    emit.start();\n\n    function moved() {\n      var point1 = pointer(that);\n      if (shifting && !lockX && !lockY) {\n        if (Math.abs(point1[0] - point[0]) > Math.abs(point1[1] - point[1])) lockY = true;\n        else lockX = true;\n      }\n      point = point1;\n      moving = true;\n      noevent();\n      move();\n    }\n\n    function move() {\n      var t;\n\n      dx = point[0] - point0[0];\n      dy = point[1] - point0[1];\n\n      switch (mode) {\n        case MODE_SPACE:\n        case MODE_DRAG: {\n          if (signX) dx = Math.max(W - w0, Math.min(E - e0, dx)), w1 = w0 + dx, e1 = e0 + dx;\n          if (signY) dy = Math.max(N - n0, Math.min(S - s0, dy)), n1 = n0 + dy, s1 = s0 + dy;\n          break;\n        }\n        case MODE_HANDLE: {\n          if (signX < 0) dx = Math.max(W - w0, Math.min(E - w0, dx)), w1 = w0 + dx, e1 = e0;\n          else if (signX > 0) dx = Math.max(W - e0, Math.min(E - e0, dx)), w1 = w0, e1 = e0 + dx;\n          if (signY < 0) dy = Math.max(N - n0, Math.min(S - n0, dy)), n1 = n0 + dy, s1 = s0;\n          else if (signY > 0) dy = Math.max(N - s0, Math.min(S - s0, dy)), n1 = n0, s1 = s0 + dy;\n          break;\n        }\n        case MODE_CENTER: {\n          if (signX) w1 = Math.max(W, Math.min(E, w0 - dx * signX)), e1 = Math.max(W, Math.min(E, e0 + dx * signX));\n          if (signY) n1 = Math.max(N, Math.min(S, n0 - dy * signY)), s1 = Math.max(N, Math.min(S, s0 + dy * signY));\n          break;\n        }\n      }\n\n      if (e1 < w1) {\n        signX *= -1;\n        t = w0, w0 = e0, e0 = t;\n        t = w1, w1 = e1, e1 = t;\n        if (type in flipX) overlay.attr(\"cursor\", cursors[type = flipX[type]]);\n      }\n\n      if (s1 < n1) {\n        signY *= -1;\n        t = n0, n0 = s0, s0 = t;\n        t = n1, n1 = s1, s1 = t;\n        if (type in flipY) overlay.attr(\"cursor\", cursors[type = flipY[type]]);\n      }\n\n      if (state.selection) selection = state.selection; // May be set by brush.move!\n      if (lockX) w1 = selection[0][0], e1 = selection[1][0];\n      if (lockY) n1 = selection[0][1], s1 = selection[1][1];\n\n      if (selection[0][0] !== w1\n          || selection[0][1] !== n1\n          || selection[1][0] !== e1\n          || selection[1][1] !== s1) {\n        state.selection = [[w1, n1], [e1, s1]];\n        redraw.call(that);\n        emit.brush();\n      }\n    }\n\n    function ended() {\n      nopropagation();\n      if (event.touches) {\n        if (event.touches.length) return;\n        if (touchending) clearTimeout(touchending);\n        touchending = setTimeout(function() { touchending = null; }, 500); // Ghost clicks are delayed!\n      } else {\n        dragEnable(event.view, moving);\n        view.on(\"keydown.brush keyup.brush mousemove.brush mouseup.brush\", null);\n      }\n      group.attr(\"pointer-events\", \"all\");\n      overlay.attr(\"cursor\", cursors.overlay);\n      if (state.selection) selection = state.selection; // May be set by brush.move (on start)!\n      if (empty(selection)) state.selection = null, redraw.call(that);\n      emit.end();\n    }\n\n    function keydowned() {\n      switch (event.keyCode) {\n        case 16: { // SHIFT\n          shifting = signX && signY;\n          break;\n        }\n        case 18: { // ALT\n          if (mode === MODE_HANDLE) {\n            if (signX) e0 = e1 - dx * signX, w0 = w1 + dx * signX;\n            if (signY) s0 = s1 - dy * signY, n0 = n1 + dy * signY;\n            mode = MODE_CENTER;\n            move();\n          }\n          break;\n        }\n        case 32: { // SPACE; takes priority over ALT\n          if (mode === MODE_HANDLE || mode === MODE_CENTER) {\n            if (signX < 0) e0 = e1 - dx; else if (signX > 0) w0 = w1 - dx;\n            if (signY < 0) s0 = s1 - dy; else if (signY > 0) n0 = n1 - dy;\n            mode = MODE_SPACE;\n            overlay.attr(\"cursor\", cursors.selection);\n            move();\n          }\n          break;\n        }\n        default: return;\n      }\n      noevent();\n    }\n\n    function keyupped() {\n      switch (event.keyCode) {\n        case 16: { // SHIFT\n          if (shifting) {\n            lockX = lockY = shifting = false;\n            move();\n          }\n          break;\n        }\n        case 18: { // ALT\n          if (mode === MODE_CENTER) {\n            if (signX < 0) e0 = e1; else if (signX > 0) w0 = w1;\n            if (signY < 0) s0 = s1; else if (signY > 0) n0 = n1;\n            mode = MODE_HANDLE;\n            move();\n          }\n          break;\n        }\n        case 32: { // SPACE\n          if (mode === MODE_SPACE) {\n            if (event.altKey) {\n              if (signX) e0 = e1 - dx * signX, w0 = w1 + dx * signX;\n              if (signY) s0 = s1 - dy * signY, n0 = n1 + dy * signY;\n              mode = MODE_CENTER;\n            } else {\n              if (signX < 0) e0 = e1; else if (signX > 0) w0 = w1;\n              if (signY < 0) s0 = s1; else if (signY > 0) n0 = n1;\n              mode = MODE_HANDLE;\n            }\n            overlay.attr(\"cursor\", cursors[type]);\n            move();\n          }\n          break;\n        }\n        default: return;\n      }\n      noevent();\n    }\n  }\n\n  function touchmoved() {\n    emitter(this, arguments).moved();\n  }\n\n  function touchended() {\n    emitter(this, arguments).ended();\n  }\n\n  function initialize() {\n    var state = this.__brush || {selection: null};\n    state.extent = number2(extent.apply(this, arguments));\n    state.dim = dim;\n    return state;\n  }\n\n  brush.extent = function(_) {\n    return arguments.length ? (extent = typeof _ === \"function\" ? _ : constant(number2(_)), brush) : extent;\n  };\n\n  brush.filter = function(_) {\n    return arguments.length ? (filter = typeof _ === \"function\" ? _ : constant(!!_), brush) : filter;\n  };\n\n  brush.touchable = function(_) {\n    return arguments.length ? (touchable = typeof _ === \"function\" ? _ : constant(!!_), brush) : touchable;\n  };\n\n  brush.handleSize = function(_) {\n    return arguments.length ? (handleSize = +_, brush) : handleSize;\n  };\n\n  brush.keyModifiers = function(_) {\n    return arguments.length ? (keys = !!_, brush) : keys;\n  };\n\n  brush.on = function() {\n    var value = listeners.on.apply(listeners, arguments);\n    return value === listeners ? brush : value;\n  };\n\n  return brush;\n}\n","import sourceEvent from \"./sourceEvent\";\nimport point from \"./point\";\n\nexport default function(node, touches, identifier) {\n  if (arguments.length < 3) identifier = touches, touches = sourceEvent().changedTouches;\n\n  for (var i = 0, n = touches ? touches.length : 0, touch; i < n; ++i) {\n    if ((touch = touches[i]).identifier === identifier) {\n      return point(node, touch);\n    }\n  }\n\n  return null;\n}\n","// Computes the decimal coefficient and exponent of the specified number x with\n// significant digits p, where x is positive and p is in [1, 21] or undefined.\n// For example, formatDecimal(1.23) returns [\"123\", 0].\nexport default function(x, p) {\n  if ((i = (x = p ? x.toExponential(p - 1) : x.toExponential()).indexOf(\"e\")) < 0) return null; // NaN, ±Infinity\n  var i, coefficient = x.slice(0, i);\n\n  // The string returned by toExponential either has the form \\d\\.\\d+e[-+]\\d+\n  // (e.g., 1.2e+3) or the form \\de[-+]\\d+ (e.g., 1e+3).\n  return [\n    coefficient.length > 1 ? coefficient[0] + coefficient.slice(2) : coefficient,\n    +x.slice(i + 1)\n  ];\n}\n","import formatDecimal from \"./formatDecimal.js\";\n\nexport default function(x) {\n  return x = formatDecimal(Math.abs(x)), x ? x[1] : NaN;\n}\n","// [[fill]align][sign][symbol][0][width][,][.precision][~][type]\nvar re = /^(?:(.)?([<>=^]))?([+\\-( ])?([$#])?(0)?(\\d+)?(,)?(\\.\\d+)?(~)?([a-z%])?$/i;\n\nexport default function formatSpecifier(specifier) {\n  if (!(match = re.exec(specifier))) throw new Error(\"invalid format: \" + specifier);\n  var match;\n  return new FormatSpecifier({\n    fill: match[1],\n    align: match[2],\n    sign: match[3],\n    symbol: match[4],\n    zero: match[5],\n    width: match[6],\n    comma: match[7],\n    precision: match[8] && match[8].slice(1),\n    trim: match[9],\n    type: match[10]\n  });\n}\n\nformatSpecifier.prototype = FormatSpecifier.prototype; // instanceof\n\nexport function FormatSpecifier(specifier) {\n  this.fill = specifier.fill === undefined ? \" \" : specifier.fill + \"\";\n  this.align = specifier.align === undefined ? \">\" : specifier.align + \"\";\n  this.sign = specifier.sign === undefined ? \"-\" : specifier.sign + \"\";\n  this.symbol = specifier.symbol === undefined ? \"\" : specifier.symbol + \"\";\n  this.zero = !!specifier.zero;\n  this.width = specifier.width === undefined ? undefined : +specifier.width;\n  this.comma = !!specifier.comma;\n  this.precision = specifier.precision === undefined ? undefined : +specifier.precision;\n  this.trim = !!specifier.trim;\n  this.type = specifier.type === undefined ? \"\" : specifier.type + \"\";\n}\n\nFormatSpecifier.prototype.toString = function() {\n  return this.fill\n      + this.align\n      + this.sign\n      + this.symbol\n      + (this.zero ? \"0\" : \"\")\n      + (this.width === undefined ? \"\" : Math.max(1, this.width | 0))\n      + (this.comma ? \",\" : \"\")\n      + (this.precision === undefined ? \"\" : \".\" + Math.max(0, this.precision | 0))\n      + (this.trim ? \"~\" : \"\")\n      + this.type;\n};\n","// Trims insignificant zeros, e.g., replaces 1.2000k with 1.2k.\nexport default function(s) {\n  out: for (var n = s.length, i = 1, i0 = -1, i1; i < n; ++i) {\n    switch (s[i]) {\n      case \".\": i0 = i1 = i; break;\n      case \"0\": if (i0 === 0) i0 = i; i1 = i; break;\n      default: if (!+s[i]) break out; if (i0 > 0) i0 = 0; break;\n    }\n  }\n  return i0 > 0 ? s.slice(0, i0) + s.slice(i1 + 1) : s;\n}\n","import formatDecimal from \"./formatDecimal.js\";\n\nexport var prefixExponent;\n\nexport default function(x, p) {\n  var d = formatDecimal(x, p);\n  if (!d) return x + \"\";\n  var coefficient = d[0],\n      exponent = d[1],\n      i = exponent - (prefixExponent = Math.max(-8, Math.min(8, Math.floor(exponent / 3))) * 3) + 1,\n      n = coefficient.length;\n  return i === n ? coefficient\n      : i > n ? coefficient + new Array(i - n + 1).join(\"0\")\n      : i > 0 ? coefficient.slice(0, i) + \".\" + coefficient.slice(i)\n      : \"0.\" + new Array(1 - i).join(\"0\") + formatDecimal(x, Math.max(0, p + i - 1))[0]; // less than 1y!\n}\n","import formatLocale from \"./locale.js\";\n\nvar locale;\nexport var format;\nexport var formatPrefix;\n\ndefaultLocale({\n  decimal: \".\",\n  thousands: \",\",\n  grouping: [3],\n  currency: [\"$\", \"\"],\n  minus: \"-\"\n});\n\nexport default function defaultLocale(definition) {\n  locale = formatLocale(definition);\n  format = locale.format;\n  formatPrefix = locale.formatPrefix;\n  return locale;\n}\n","import formatDecimal from \"./formatDecimal.js\";\n\nexport default function(x, p) {\n  var d = formatDecimal(x, p);\n  if (!d) return x + \"\";\n  var coefficient = d[0],\n      exponent = d[1];\n  return exponent < 0 ? \"0.\" + new Array(-exponent).join(\"0\") + coefficient\n      : coefficient.length > exponent + 1 ? coefficient.slice(0, exponent + 1) + \".\" + coefficient.slice(exponent + 1)\n      : coefficient + new Array(exponent - coefficient.length + 2).join(\"0\");\n}\n","import formatPrefixAuto from \"./formatPrefixAuto.js\";\nimport formatRounded from \"./formatRounded.js\";\n\nexport default {\n  \"%\": function(x, p) { return (x * 100).toFixed(p); },\n  \"b\": function(x) { return Math.round(x).toString(2); },\n  \"c\": function(x) { return x + \"\"; },\n  \"d\": function(x) { return Math.round(x).toString(10); },\n  \"e\": function(x, p) { return x.toExponential(p); },\n  \"f\": function(x, p) { return x.toFixed(p); },\n  \"g\": function(x, p) { return x.toPrecision(p); },\n  \"o\": function(x) { return Math.round(x).toString(8); },\n  \"p\": function(x, p) { return formatRounded(x * 100, p); },\n  \"r\": formatRounded,\n  \"s\": formatPrefixAuto,\n  \"X\": function(x) { return Math.round(x).toString(16).toUpperCase(); },\n  \"x\": function(x) { return Math.round(x).toString(16); }\n};\n","export default function(x) {\n  return x;\n}\n","import exponent from \"./exponent.js\";\nimport formatGroup from \"./formatGroup.js\";\nimport formatNumerals from \"./formatNumerals.js\";\nimport formatSpecifier from \"./formatSpecifier.js\";\nimport formatTrim from \"./formatTrim.js\";\nimport formatTypes from \"./formatTypes.js\";\nimport {prefixExponent} from \"./formatPrefixAuto.js\";\nimport identity from \"./identity.js\";\n\nvar map = Array.prototype.map,\n    prefixes = [\"y\",\"z\",\"a\",\"f\",\"p\",\"n\",\"µ\",\"m\",\"\",\"k\",\"M\",\"G\",\"T\",\"P\",\"E\",\"Z\",\"Y\"];\n\nexport default function(locale) {\n  var group = locale.grouping === undefined || locale.thousands === undefined ? identity : formatGroup(map.call(locale.grouping, Number), locale.thousands + \"\"),\n      currencyPrefix = locale.currency === undefined ? \"\" : locale.currency[0] + \"\",\n      currencySuffix = locale.currency === undefined ? \"\" : locale.currency[1] + \"\",\n      decimal = locale.decimal === undefined ? \".\" : locale.decimal + \"\",\n      numerals = locale.numerals === undefined ? identity : formatNumerals(map.call(locale.numerals, String)),\n      percent = locale.percent === undefined ? \"%\" : locale.percent + \"\",\n      minus = locale.minus === undefined ? \"-\" : locale.minus + \"\",\n      nan = locale.nan === undefined ? \"NaN\" : locale.nan + \"\";\n\n  function newFormat(specifier) {\n    specifier = formatSpecifier(specifier);\n\n    var fill = specifier.fill,\n        align = specifier.align,\n        sign = specifier.sign,\n        symbol = specifier.symbol,\n        zero = specifier.zero,\n        width = specifier.width,\n        comma = specifier.comma,\n        precision = specifier.precision,\n        trim = specifier.trim,\n        type = specifier.type;\n\n    // The \"n\" type is an alias for \",g\".\n    if (type === \"n\") comma = true, type = \"g\";\n\n    // The \"\" type, and any invalid type, is an alias for \".12~g\".\n    else if (!formatTypes[type]) precision === undefined && (precision = 12), trim = true, type = \"g\";\n\n    // If zero fill is specified, padding goes after sign and before digits.\n    if (zero || (fill === \"0\" && align === \"=\")) zero = true, fill = \"0\", align = \"=\";\n\n    // Compute the prefix and suffix.\n    // For SI-prefix, the suffix is lazily computed.\n    var prefix = symbol === \"$\" ? currencyPrefix : symbol === \"#\" && /[boxX]/.test(type) ? \"0\" + type.toLowerCase() : \"\",\n        suffix = symbol === \"$\" ? currencySuffix : /[%p]/.test(type) ? percent : \"\";\n\n    // What format function should we use?\n    // Is this an integer type?\n    // Can this type generate exponential notation?\n    var formatType = formatTypes[type],\n        maybeSuffix = /[defgprs%]/.test(type);\n\n    // Set the default precision if not specified,\n    // or clamp the specified precision to the supported range.\n    // For significant precision, it must be in [1, 21].\n    // For fixed precision, it must be in [0, 20].\n    precision = precision === undefined ? 6\n        : /[gprs]/.test(type) ? Math.max(1, Math.min(21, precision))\n        : Math.max(0, Math.min(20, precision));\n\n    function format(value) {\n      var valuePrefix = prefix,\n          valueSuffix = suffix,\n          i, n, c;\n\n      if (type === \"c\") {\n        valueSuffix = formatType(value) + valueSuffix;\n        value = \"\";\n      } else {\n        value = +value;\n\n        // Determine the sign. -0 is not less than 0, but 1 / -0 is!\n        var valueNegative = value < 0 || 1 / value < 0;\n\n        // Perform the initial formatting.\n        value = isNaN(value) ? nan : formatType(Math.abs(value), precision);\n\n        // Trim insignificant zeros.\n        if (trim) value = formatTrim(value);\n\n        // If a negative value rounds to zero after formatting, and no explicit positive sign is requested, hide the sign.\n        if (valueNegative && +value === 0 && sign !== \"+\") valueNegative = false;\n\n        // Compute the prefix and suffix.\n        valuePrefix = (valueNegative ? (sign === \"(\" ? sign : minus) : sign === \"-\" || sign === \"(\" ? \"\" : sign) + valuePrefix;\n        valueSuffix = (type === \"s\" ? prefixes[8 + prefixExponent / 3] : \"\") + valueSuffix + (valueNegative && sign === \"(\" ? \")\" : \"\");\n\n        // Break the formatted value into the integer “value” part that can be\n        // grouped, and fractional or exponential “suffix” part that is not.\n        if (maybeSuffix) {\n          i = -1, n = value.length;\n          while (++i < n) {\n            if (c = value.charCodeAt(i), 48 > c || c > 57) {\n              valueSuffix = (c === 46 ? decimal + value.slice(i + 1) : value.slice(i)) + valueSuffix;\n              value = value.slice(0, i);\n              break;\n            }\n          }\n        }\n      }\n\n      // If the fill character is not \"0\", grouping is applied before padding.\n      if (comma && !zero) value = group(value, Infinity);\n\n      // Compute the padding.\n      var length = valuePrefix.length + value.length + valueSuffix.length,\n          padding = length < width ? new Array(width - length + 1).join(fill) : \"\";\n\n      // If the fill character is \"0\", grouping is applied after padding.\n      if (comma && zero) value = group(padding + value, padding.length ? width - valueSuffix.length : Infinity), padding = \"\";\n\n      // Reconstruct the final output based on the desired alignment.\n      switch (align) {\n        case \"<\": value = valuePrefix + value + valueSuffix + padding; break;\n        case \"=\": value = valuePrefix + padding + value + valueSuffix; break;\n        case \"^\": value = padding.slice(0, length = padding.length >> 1) + valuePrefix + value + valueSuffix + padding.slice(length); break;\n        default: value = padding + valuePrefix + value + valueSuffix; break;\n      }\n\n      return numerals(value);\n    }\n\n    format.toString = function() {\n      return specifier + \"\";\n    };\n\n    return format;\n  }\n\n  function formatPrefix(specifier, value) {\n    var f = newFormat((specifier = formatSpecifier(specifier), specifier.type = \"f\", specifier)),\n        e = Math.max(-8, Math.min(8, Math.floor(exponent(value) / 3))) * 3,\n        k = Math.pow(10, -e),\n        prefix = prefixes[8 + e / 3];\n    return function(value) {\n      return f(k * value) + prefix;\n    };\n  }\n\n  return {\n    format: newFormat,\n    formatPrefix: formatPrefix\n  };\n}\n","export default function(grouping, thousands) {\n  return function(value, width) {\n    var i = value.length,\n        t = [],\n        j = 0,\n        g = grouping[0],\n        length = 0;\n\n    while (i > 0 && g > 0) {\n      if (length + g + 1 > width) g = Math.max(1, width - length);\n      t.push(value.substring(i -= g, i + g));\n      if ((length += g + 1) > width) break;\n      g = grouping[j = (j + 1) % grouping.length];\n    }\n\n    return t.reverse().join(thousands);\n  };\n}\n","export default function(numerals) {\n  return function(value) {\n    return value.replace(/[0-9]/g, function(i) {\n      return numerals[+i];\n    });\n  };\n}\n","import exponent from \"./exponent.js\";\n\nexport default function(step) {\n  return Math.max(0, -exponent(Math.abs(step)));\n}\n","import exponent from \"./exponent.js\";\n\nexport default function(step, value) {\n  return Math.max(0, Math.max(-8, Math.min(8, Math.floor(exponent(value) / 3))) * 3 - exponent(Math.abs(step)));\n}\n","import exponent from \"./exponent.js\";\n\nexport default function(step, max) {\n  step = Math.abs(step), max = Math.abs(max) - step;\n  return Math.max(0, exponent(max) - exponent(step)) + 1;\n}\n","var e10 = Math.sqrt(50),\n    e5 = Math.sqrt(10),\n    e2 = Math.sqrt(2);\n\nexport default function(start, stop, count) {\n  var reverse,\n      i = -1,\n      n,\n      ticks,\n      step;\n\n  stop = +stop, start = +start, count = +count;\n  if (start === stop && count > 0) return [start];\n  if (reverse = stop < start) n = start, start = stop, stop = n;\n  if ((step = tickIncrement(start, stop, count)) === 0 || !isFinite(step)) return [];\n\n  if (step > 0) {\n    start = Math.ceil(start / step);\n    stop = Math.floor(stop / step);\n    ticks = new Array(n = Math.ceil(stop - start + 1));\n    while (++i < n) ticks[i] = (start + i) * step;\n  } else {\n    start = Math.floor(start * step);\n    stop = Math.ceil(stop * step);\n    ticks = new Array(n = Math.ceil(start - stop + 1));\n    while (++i < n) ticks[i] = (start - i) / step;\n  }\n\n  if (reverse) ticks.reverse();\n\n  return ticks;\n}\n\nexport function tickIncrement(start, stop, count) {\n  var step = (stop - start) / Math.max(0, count),\n      power = Math.floor(Math.log(step) / Math.LN10),\n      error = step / Math.pow(10, power);\n  return power >= 0\n      ? (error >= e10 ? 10 : error >= e5 ? 5 : error >= e2 ? 2 : 1) * Math.pow(10, power)\n      : -Math.pow(10, -power) / (error >= e10 ? 10 : error >= e5 ? 5 : error >= e2 ? 2 : 1);\n}\n\nexport function tickStep(start, stop, count) {\n  var step0 = Math.abs(stop - start) / Math.max(0, count),\n      step1 = Math.pow(10, Math.floor(Math.log(step0) / Math.LN10)),\n      error = step0 / step1;\n  if (error >= e10) step1 *= 10;\n  else if (error >= e5) step1 *= 5;\n  else if (error >= e2) step1 *= 2;\n  return stop < start ? -step1 : step1;\n}\n","export default function(a, b) {\n  return a < b ? -1 : a > b ? 1 : a >= b ? 0 : NaN;\n}\n","import ascending from \"./ascending.js\";\nimport bisector from \"./bisector.js\";\n\nvar ascendingBisect = bisector(ascending);\nexport var bisectRight = ascendingBisect.right;\nexport var bisectLeft = ascendingBisect.left;\nexport default bisectRight;\n","import ascending from \"./ascending.js\";\n\nexport default function(compare) {\n  if (compare.length === 1) compare = ascendingComparator(compare);\n  return {\n    left: function(a, x, lo, hi) {\n      if (lo == null) lo = 0;\n      if (hi == null) hi = a.length;\n      while (lo < hi) {\n        var mid = lo + hi >>> 1;\n        if (compare(a[mid], x) < 0) lo = mid + 1;\n        else hi = mid;\n      }\n      return lo;\n    },\n    right: function(a, x, lo, hi) {\n      if (lo == null) lo = 0;\n      if (hi == null) hi = a.length;\n      while (lo < hi) {\n        var mid = lo + hi >>> 1;\n        if (compare(a[mid], x) > 0) hi = mid;\n        else lo = mid + 1;\n      }\n      return lo;\n    }\n  };\n}\n\nfunction ascendingComparator(f) {\n  return function(d, x) {\n    return ascending(f(d), x);\n  };\n}\n","export default function(a, b) {\n  return a = +a, b = +b, function(t) {\n    return Math.round(a * (1 - t) + b * t);\n  };\n}\n","export default function(x) {\n  return +x;\n}\n","import {bisect} from \"d3-array\";\nimport {interpolate as interpolateValue, interpolateNumber, interpolateRound} from \"d3-interpolate\";\nimport constant from \"./constant.js\";\nimport number from \"./number.js\";\n\nvar unit = [0, 1];\n\nexport function identity(x) {\n  return x;\n}\n\nfunction normalize(a, b) {\n  return (b -= (a = +a))\n      ? function(x) { return (x - a) / b; }\n      : constant(isNaN(b) ? NaN : 0.5);\n}\n\nfunction clamper(a, b) {\n  var t;\n  if (a > b) t = a, a = b, b = t;\n  return function(x) { return Math.max(a, Math.min(b, x)); };\n}\n\n// normalize(a, b)(x) takes a domain value x in [a,b] and returns the corresponding parameter t in [0,1].\n// interpolate(a, b)(t) takes a parameter t in [0,1] and returns the corresponding range value x in [a,b].\nfunction bimap(domain, range, interpolate) {\n  var d0 = domain[0], d1 = domain[1], r0 = range[0], r1 = range[1];\n  if (d1 < d0) d0 = normalize(d1, d0), r0 = interpolate(r1, r0);\n  else d0 = normalize(d0, d1), r0 = interpolate(r0, r1);\n  return function(x) { return r0(d0(x)); };\n}\n\nfunction polymap(domain, range, interpolate) {\n  var j = Math.min(domain.length, range.length) - 1,\n      d = new Array(j),\n      r = new Array(j),\n      i = -1;\n\n  // Reverse descending domains.\n  if (domain[j] < domain[0]) {\n    domain = domain.slice().reverse();\n    range = range.slice().reverse();\n  }\n\n  while (++i < j) {\n    d[i] = normalize(domain[i], domain[i + 1]);\n    r[i] = interpolate(range[i], range[i + 1]);\n  }\n\n  return function(x) {\n    var i = bisect(domain, x, 1, j) - 1;\n    return r[i](d[i](x));\n  };\n}\n\nexport function copy(source, target) {\n  return target\n      .domain(source.domain())\n      .range(source.range())\n      .interpolate(source.interpolate())\n      .clamp(source.clamp())\n      .unknown(source.unknown());\n}\n\nexport function transformer() {\n  var domain = unit,\n      range = unit,\n      interpolate = interpolateValue,\n      transform,\n      untransform,\n      unknown,\n      clamp = identity,\n      piecewise,\n      output,\n      input;\n\n  function rescale() {\n    var n = Math.min(domain.length, range.length);\n    if (clamp !== identity) clamp = clamper(domain[0], domain[n - 1]);\n    piecewise = n > 2 ? polymap : bimap;\n    output = input = null;\n    return scale;\n  }\n\n  function scale(x) {\n    return isNaN(x = +x) ? unknown : (output || (output = piecewise(domain.map(transform), range, interpolate)))(transform(clamp(x)));\n  }\n\n  scale.invert = function(y) {\n    return clamp(untransform((input || (input = piecewise(range, domain.map(transform), interpolateNumber)))(y)));\n  };\n\n  scale.domain = function(_) {\n    return arguments.length ? (domain = Array.from(_, number), rescale()) : domain.slice();\n  };\n\n  scale.range = function(_) {\n    return arguments.length ? (range = Array.from(_), rescale()) : range.slice();\n  };\n\n  scale.rangeRound = function(_) {\n    return range = Array.from(_), interpolate = interpolateRound, rescale();\n  };\n\n  scale.clamp = function(_) {\n    return arguments.length ? (clamp = _ ? true : identity, rescale()) : clamp !== identity;\n  };\n\n  scale.interpolate = function(_) {\n    return arguments.length ? (interpolate = _, rescale()) : interpolate;\n  };\n\n  scale.unknown = function(_) {\n    return arguments.length ? (unknown = _, scale) : unknown;\n  };\n\n  return function(t, u) {\n    transform = t, untransform = u;\n    return rescale();\n  };\n}\n\nexport default function continuous() {\n  return transformer()(identity, identity);\n}\n","export default function(x) {\n  return function() {\n    return x;\n  };\n}\n","export function initRange(domain, range) {\n  switch (arguments.length) {\n    case 0: break;\n    case 1: this.range(domain); break;\n    default: this.range(range).domain(domain); break;\n  }\n  return this;\n}\n\nexport function initInterpolator(domain, interpolator) {\n  switch (arguments.length) {\n    case 0: break;\n    case 1: {\n      if (typeof domain === \"function\") this.interpolator(domain);\n      else this.range(domain);\n      break;\n    }\n    default: {\n      this.domain(domain);\n      if (typeof interpolator === \"function\") this.interpolator(interpolator);\n      else this.range(interpolator);\n      break;\n    }\n  }\n  return this;\n}\n","import {tickStep} from \"d3-array\";\nimport {format, formatPrefix, formatSpecifier, precisionFixed, precisionPrefix, precisionRound} from \"d3-format\";\n\nexport default function(start, stop, count, specifier) {\n  var step = tickStep(start, stop, count),\n      precision;\n  specifier = formatSpecifier(specifier == null ? \",f\" : specifier);\n  switch (specifier.type) {\n    case \"s\": {\n      var value = Math.max(Math.abs(start), Math.abs(stop));\n      if (specifier.precision == null && !isNaN(precision = precisionPrefix(step, value))) specifier.precision = precision;\n      return formatPrefix(specifier, value);\n    }\n    case \"\":\n    case \"e\":\n    case \"g\":\n    case \"p\":\n    case \"r\": {\n      if (specifier.precision == null && !isNaN(precision = precisionRound(step, Math.max(Math.abs(start), Math.abs(stop))))) specifier.precision = precision - (specifier.type === \"e\");\n      break;\n    }\n    case \"f\":\n    case \"%\": {\n      if (specifier.precision == null && !isNaN(precision = precisionFixed(step))) specifier.precision = precision - (specifier.type === \"%\") * 2;\n      break;\n    }\n  }\n  return format(specifier);\n}\n","import {ticks, tickIncrement} from \"d3-array\";\nimport continuous, {copy} from \"./continuous.js\";\nimport {initRange} from \"./init.js\";\nimport tickFormat from \"./tickFormat.js\";\n\nexport function linearish(scale) {\n  var domain = scale.domain;\n\n  scale.ticks = function(count) {\n    var d = domain();\n    return ticks(d[0], d[d.length - 1], count == null ? 10 : count);\n  };\n\n  scale.tickFormat = function(count, specifier) {\n    var d = domain();\n    return tickFormat(d[0], d[d.length - 1], count == null ? 10 : count, specifier);\n  };\n\n  scale.nice = function(count) {\n    if (count == null) count = 10;\n\n    var d = domain(),\n        i0 = 0,\n        i1 = d.length - 1,\n        start = d[i0],\n        stop = d[i1],\n        step;\n\n    if (stop < start) {\n      step = start, start = stop, stop = step;\n      step = i0, i0 = i1, i1 = step;\n    }\n\n    step = tickIncrement(start, stop, count);\n\n    if (step > 0) {\n      start = Math.floor(start / step) * step;\n      stop = Math.ceil(stop / step) * step;\n      step = tickIncrement(start, stop, count);\n    } else if (step < 0) {\n      start = Math.ceil(start * step) / step;\n      stop = Math.floor(stop * step) / step;\n      step = tickIncrement(start, stop, count);\n    }\n\n    if (step > 0) {\n      d[i0] = Math.floor(start / step) * step;\n      d[i1] = Math.ceil(stop / step) * step;\n      domain(d);\n    } else if (step < 0) {\n      d[i0] = Math.ceil(start * step) / step;\n      d[i1] = Math.floor(stop * step) / step;\n      domain(d);\n    }\n\n    return scale;\n  };\n\n  return scale;\n}\n\nexport default function linear() {\n  var scale = continuous();\n\n  scale.copy = function() {\n    return copy(scale, linear());\n  };\n\n  initRange.apply(scale, arguments);\n\n  return linearish(scale);\n}\n","/**\n * @fileoverview A collection of Ideogram methods that don't fit elsewhere.\n */\n\nimport {select, selectAll} from 'd3-selection';\nimport * as d3fetch from 'd3-fetch';\nimport * as d3brush from 'd3-brush';\nimport * as d3dispatch from 'd3-dispatch';\nimport * as d3format from 'd3-format';\nimport {scaleLinear} from 'd3-scale';\nimport {max} from 'd3-array';\n\nvar d3 = Object.assign(\n  {}, d3fetch, d3brush, d3dispatch, d3format\n);\n\nd3.select = select;\nd3.selectAll = selectAll;\nd3.scaleLinear = scaleLinear;\nd3.max = max;\n\n/**\n * Is the assembly in this.config an NCBI Assembly accession?\n *\n * @returns {boolean}\n */\nfunction assemblyIsAccession() {\n  return (\n    'assembly' in this.config &&\n    /(GCF_|GCA_)/.test(this.config.assembly)\n  );\n}\n\n/**\n * Is the assembly in this.config not from GenBank?\n *\n * @returns {boolean}\n */\nfunction hasNonGenBankAssembly(ideo) {\n  return (\n    'assembly' in ideo.config &&\n    /(GCA_)/.test(ideo.config.assembly) === false\n  );\n}\n\n/**\n * Is the assembly in this.config from GenBank?\n *\n * @returns {boolean}\n */\nfunction hasGenBankAssembly(ideo) {\n  return (\n    'assembly' in ideo.config &&\n    /(GCA_)/.test(ideo.config.assembly)\n  );\n}\n\n/**\n * Returns directory used to fetch data for bands and annotations\n *\n * This simplifies ideogram configuration.  By default, the dataDir is\n * set to an external CDN unless we're serving from the local host, in\n * which case dataDir is deduced from the \"src\" attribute of the ideogram\n * script loaded in the document.\n *\n * @returns {String}\n */\nfunction getDataDir() {\n  var script, tmp, protocol, dataDir, ideogramInLeaf,\n    scripts = document.scripts,\n    host = location.host.split(':')[0],\n    version = Ideogram.version;\n\n  if (host !== 'localhost' && host !== '127.0.0.1') {\n    return (\n      'https://cdn.jsdelivr.net/npm/ideogram@' + version + '/dist/data/bands/native/'\n    );\n  }\n\n  for (var i = 0; i < scripts.length; i++) {\n    script = scripts[i];\n    ideogramInLeaf = /ideogram/.test(script.src.split('/').slice(-1));\n    if ('src' in script && ideogramInLeaf) {\n      tmp = script.src.split('//');\n      protocol = tmp[0];\n      tmp = '/' + tmp[1].split('/').slice(0, -2).join('/');\n      dataDir = protocol + '//' + tmp + '/data/bands/native/';\n      return dataDir;\n    }\n  }\n  return '../data/bands/native/';\n}\n\n/**\n * Rounds an SVG coordinates to two decimal places\n *\n * @param coord SVG coordinate, e.g. 42.1234567890\n * @returns {number} Rounded value, e.g. 42.12\n */\nfunction round(coord) {\n  // Per http://stackoverflow.com/a/9453447, below method is fastest\n  return Math.round(coord * 100) / 100;\n}\n\nfunction onDidRotate(chrModel) {\n  call(this.onDidRotateCallback, chrModel);\n}\n\n/**\n * Get ideogram SVG container\n */\nfunction getSvg() {\n  return d3.select(this.selector).node();\n}\n\nfunction fetch(url, contentType) {\n  var ideo = this,\n    config = ideo.config,\n    headers = new Headers();\n\n  if (config.accessToken) {\n    headers = new Headers({Authorization: 'Bearer ' + config.accessToken});\n  }\n\n  if (contentType === 'text') {\n    return d3.text(url, {headers: headers});\n  } else {\n    return d3.json(url, {headers: headers});\n  }\n}\n\n/**\n * Get organism's taxid (NCBI Taxonomy ID) given its common or scientific name\n */\nfunction getTaxid(name) {\n  var organism, taxid, commonName, scientificName,\n    ideo = this,\n    organisms = ideo.organisms;\n\n  name = slug(name);\n\n  for (taxid in organisms) {\n    organism = organisms[taxid];\n    commonName = slug(organism.commonName);\n    scientificName = slug(organism.scientificName);\n    if (commonName === name || scientificName === name) {\n      return taxid;\n    }\n  }\n\n  return null;\n}\n\n/**\n * Get organism's common name given its taxid\n */\nfunction getCommonName(taxid) {\n  var ideo = this;\n  if (taxid in ideo.organisms) {\n    return ideo.organisms[taxid].commonName;\n  }\n  return null;\n}\n\n/**\n * Get organism's scientific name given its taxid\n */\nfunction getScientificName(taxid) {\n  var ideo = this;\n  if (taxid in ideo.organisms) {\n    return ideo.organisms[taxid].scientificName;\n  }\n  return null;\n}\n\n/**\n* Examples:\n* \"Homo sapiens\" -> \"homo-sapiens\"\n* \"Canis lupus familiaris\" -> \"canis-lupus-familiaris\"\n*/\nfunction slug(value) {\n  return value.toLowerCase().replace(/ /g, '-');\n}\n\nexport {\n  assemblyIsAccession, hasNonGenBankAssembly, hasGenBankAssembly, getDataDir,\n  round, onDidRotate, getSvg, fetch, d3, getTaxid, getCommonName,\n  getScientificName, slug\n};\n","import {Selection, root} from \"./selection/index\";\n\nexport default function(selector) {\n  return typeof selector === \"string\"\n      ? new Selection([document.querySelectorAll(selector)], [document.documentElement])\n      : new Selection([selector == null ? [] : selector], root);\n}\n","export default function max(values, valueof) {\n  let max;\n  if (valueof === undefined) {\n    for (const value of values) {\n      if (value != null\n          && (max < value || (max === undefined && value >= value))) {\n        max = value;\n      }\n    }\n  } else {\n    let index = -1;\n    for (let value of values) {\n      if ((value = valueof(value, ++index, values)) != null\n          && (max < value || (max === undefined && value >= value))) {\n        max = value;\n      }\n    }\n  }\n  return max;\n}\n","var organismMetadata = {\n  9606: {\n    commonName: 'Human',\n    scientificName: 'Homo sapiens',\n    assemblies: {\n      default: 'GCF_000001405.26', // GRCh38\n      GRCh38: 'GCF_000001405.26',\n      GRCh37: 'GCF_000001405.13',\n      NCBI36: 'GCF_000001405.12'\n    }\n  },\n  10090: {\n    commonName: 'Mouse',\n    scientificName: 'Mus musculus',\n    assemblies: {\n      default: 'GCF_000001635.20', // GRCm38\n      GRCm38: 'GCF_000001635.20',\n      MGSCv37: 'GCF_000001635.18'\n    }\n  },\n  9598: {\n    commonName: 'Chimpanzee',\n    scientificName: 'Pan troglodytes',\n    assemblies: {\n      'default': 'GCF_000001515.7',\n      'Pan_tro 3.0': 'GCF_000001515.7'\n    }\n  },\n  10116: {\n    commonName: 'Rat',\n    scientificName: 'Rattus norvegicus',\n    assemblies: {\n      'default': 'GCF_000001895.5',\n      'Rnor_6.0': 'GCF_000001895.5'\n    }\n  },\n  3702: {\n    commonName: 'Thale cress',\n    scientificName: 'Arabidopsis thaliana',\n    assemblies: {\n      default: 'GCF_000001735.3', // TAIR10\n      TAIR10: 'GCF_000001735.3'\n    }\n  },\n  4530: {\n    commonName: 'Rice',\n    scientificName: 'Oryza sativa',\n    assemblies: {\n      'default': 'GCA_001433935.1',\n      'IRGSP-1.0': 'GCA_001433935.1'\n    }\n  },\n  4577: {\n    commonName: 'Maize',\n    scientificName: 'Zea mays',\n    assemblies: {\n      'default': 'GCA_000005005.5',\n      'IRGSP-1.0': 'GCA_001433935.1'\n    }\n  },\n  4641: {\n    commonName: 'Banana',\n    scientificName: 'Musa acuminata',\n    assemblies: {\n      default: 'mock'\n    }\n  },\n  7227: {\n    commonName: 'Fly',\n    scientificName: 'Drosophila melanogaster',\n    assemblies: {\n      'default': 'GCA_000001215.4',\n      'Release 6 plus ISO1 MT': 'GCA_000001215.4'\n    }\n  },\n  7165: {\n    commonName: 'Mosquito',\n    scientificName: 'Anopheles gambiae',\n    assemblies: {\n      default: ''\n    }\n  },\n  746128: {\n    commonName: 'Aspergillis fumigatus',\n    scientificName: 'Aspergillis fumigatus',\n    assemblies: {\n      default: ''\n    }\n  },\n  227321: {\n    commonName: 'Aspergillus nidulans',\n    scientificName: '',\n    assemblies: {\n      default: ''\n    }\n  },\n  5061: {\n    commonName: 'black mold',\n    scientificName: 'Aspergillus niger',\n    assemblies: {\n      default: ''\n    }\n  },\n  5062: {\n    commonName: 'koji',\n    scientificName: 'Aspergillus oryzae',\n    assemblies: {\n      default: ''\n    }\n  },\n  15368: {\n    commonName: '',\n    scientificName: 'Brachypodium distachyon',\n    assemblies: {\n      default: ''\n    }\n  },\n  60711: {\n    commonName: '',\n    scientificName: 'Chlorocebus sabaeus',\n    assemblies: {\n      default: ''\n    }\n  },\n  7719: {\n    commonName: 'Vase tunicate',\n    scientificName: 'Ciona intestinalis',\n    assemblies: {\n      default: ''\n    }\n  },\n  9685: {\n    commonName: 'Cat',\n    scientificName: 'Felis catus',\n    assemblies: {\n      default: ''\n    }\n  },\n  9031: {\n    commonName: 'Chicken',\n    scientificName: 'Gallus gallus',\n    assemblies: {\n      default: ''\n    }\n  },\n  9593: {\n    commonName: 'Gorilla',\n    scientificName: 'Gorilla gorilla',\n    assemblies: {\n      default: ''\n    }\n  },\n  4513: {\n    commonName: 'Barley',\n    scientificName: 'Hordeum vulgare',\n    assemblies: {\n      default: ''\n    }\n  },\n  9541: {\n    commonName: 'Crab-eating macaque',\n    scientificName: 'Macaca fascicularis',\n    assemblies: {\n      default: ''\n    }\n  },\n  9544: {\n    commonName: 'Rhesus macaque',\n    scientificName: 'Macaca mulatta',\n    assemblies: {\n      default: ''\n    }\n  },\n  9597: {\n    commonName: 'Bonobo',\n    scientificName: 'Pan paniscus',\n    assemblies: {\n      default: ''\n    }\n  },\n  9615: {\n    commonName: 'Dog',\n    scientificName: 'Canis lupus familiaris',\n    assemblies: {\n      default: ''\n    }\n  }\n};\n\nexport {organismMetadata};\n","var staticColors, staticCss, staticGradients;\n\nstaticColors = [\n  ['gneg', '#FFF', '#FFF', '#DDD'],\n  ['gpos25', '#C8C8C8', '#DDD', '#BBB'],\n  ['gpos33', '#BBB', '#BBB', '#AAA'],\n  ['gpos50', '#999', '#AAA', '#888'],\n  ['gpos66', '#888', '#888', '#666'],\n  ['gpos75', '#777', '#777', '#444'],\n  ['gpos100', '#444', '#666', '#000'],\n  ['acen', '#FEE', '#FEE', '#FDD'],\n  ['noBands', '#BBB', '#BBB', '#AAA']\n];\n\nstaticCss =\n  '#_ideogram {padding-left: 5px;} ' +\n  '#_ideogram .labeled {padding-left: 15px;} ' +\n  '#_ideogram.labeledLeft {padding-left: 15px; padding-top: 15px;} ' +\n  // Tahoma has great readability and space utilization at small sizes\n  // More: http://ux.stackexchange.com/a/3334\n  '#_ideogram text {font: 9px Tahoma; fill: #000;} ' +\n  '#_ideogram .italic {font-style: italic;} ' +\n  '#_ideogram .chromosome {cursor: pointer; fill: #AAA;}' +\n  '#_ideogram.no-rotate .chromosome {cursor: default;} ' +\n  '#_ideogram .annot {cursor: pointer;}' +\n  '#_ideogram .chrSetLabel {font-weight: bolder;}' +\n  '#_ideogram .ghost {opacity: 0.2;}' +\n  '#_ideogram .hidden {display: none;}' +\n  '#_ideogram .bandLabelStalk line {stroke: #AAA; stroke-width: 1;}' +\n  '#_ideogram .syntenyBorder {stroke:#AAA;stroke-width:1;}' +\n  '#_ideogram rect.cursor {' +\n  '  fill: #F00;' +\n  '  stroke: #F00;' +\n  '  fill-opacity: .3;' +\n  '  shape-rendering: crispEdges;' +\n  '}' +\n  '#_ideogram .brush .selection {' +\n  '  fill: #F00;' +\n  '  stroke: #F00;' +\n  '  fill-opacity: .3;' +\n  '  shape-rendering: crispEdges;' +\n  '}' +\n  '#_ideogram .noBands {fill: #AAA;}' +\n  // NCBI stain density colors\n  '#_ideogram .gneg {fill: #FFF}' +\n  '#_ideogram .gpos25 {fill: #BBB}' +\n  '#_ideogram .gpos33 {fill: #AAA}' +\n  '#_ideogram .gpos50 {fill: #888}' +\n  '#_ideogram .gpos66 {fill: #666}' +\n  '#_ideogram .gpos75 {fill: #444}' +\n  '#_ideogram .gpos100 {fill: #000}' +\n  '#_ideogram .gpos {fill: #000}' +\n  '#_ideogram .acen {fill: #FDD}' +\n  '#_ideogram .stalk {fill: #CCE;}' +\n  '#_ideogram .gvar {fill: #DDF}' +\n  // Used when overlaid with annotations\n  '#_ideogram.faint .gneg {fill: #FFF}' +\n  '#_ideogram.faint .gpos25 {fill: #EEE}' +\n  '#_ideogram.faint .gpos33 {fill: #EEE}' +\n  '#_ideogram.faint .gpos50 {fill: #EEE}' +\n  '#_ideogram.faint .gpos66 {fill: #EEE}' +\n  '#_ideogram.faint .gpos75 {fill: #EEE}' +\n  '#_ideogram.faint .gpos100 {fill: #DDD}' +\n  '#_ideogram.faint .gpos {fill: #DDD}' +\n  '#_ideogram.faint .acen {fill: #FEE}' +\n  '#_ideogram.faint .stalk {fill: #EEF;}' +\n  '#_ideogram.faint .gvar {fill: #EEF}' +\n  // For sheen, i.e. the soft shine in chromosomes\n  '#_ideogram .gneg {fill: url(\"#gneg\")} ' +\n  '#_ideogram .gpos25 {fill: url(\"#gpos25\")} ' +\n  '#_ideogram .gpos33 {fill: url(\"#gpos33\")} ' +\n  '#_ideogram .gpos50 {fill: url(\"#gpos50\")} ' +\n  '#_ideogram .gpos66 {fill: url(\"#gpos66\")} ' +\n  '#_ideogram .gpos75 {fill: url(\"#gpos75\")} ' +\n  '#_ideogram .gpos100 {fill: url(\"#gpos100\")} ' +\n  '#_ideogram .gpos {fill: url(\"#gpos100\")} ' +\n  '#_ideogram .acen {fill: url(\"#acen\")} ' +\n  '#_ideogram .stalk {fill: url(\"#stalk\")} ' +\n  '#_ideogram .gvar {fill: url(\"#gvar\")} ' +\n  '#_ideogram .noBands {fill: url(\"#noBands\")} ' +\n  '#_ideogram .chromosome {fill: url(\"#noBands\")} ';\n\nstaticGradients =\n  '<pattern id=\"stalk\" width=\"2\" height=\"1\" patternUnits=\"userSpaceOnUse\" ' +\n  'patternTransform=\"rotate(30 0 0)\">' +\n  '<rect x=\"0\" y=\"0\" width=\"10\" height=\"2\" fill=\"#CCE\" /> ' +\n  '<line x1=\"0\" y1=\"0\" x2=\"0\" y2=\"100%\" style=\"stroke:#88B; ' +\n  'stroke-width:0.7;\" />' +\n  '</pattern>' +\n  '<pattern id=\"gvar\" width=\"2\" height=\"1\" patternUnits=\"userSpaceOnUse\" ' +\n  'patternTransform=\"rotate(-30 0 0)\">' +\n  '<rect x=\"0\" y=\"0\" width=\"10\" height=\"2\" fill=\"#DDF\" /> ' +\n  '<line x1=\"0\" y1=\"0\" x2=\"0\" y2=\"100%\" style=\"stroke:#99C; ' +\n  'stroke-width:0.7;\" />' +\n  '</pattern>';\n\nexport {staticColors, staticCss, staticGradients};\n","import {organismMetadata} from './organism-metadata';\nimport {staticCss} from './../bands/styles';\n\nfunction configurePloidy(ideo) {\n  if (!ideo.config.ploidy) ideo.config.ploidy = 1;\n\n  if (ideo.config.ploidy > 1) {\n    ideo.sexChromosomes = {};\n    if (!ideo.config.sex) {\n      // Default to 'male' per human, mouse reference genomes.\n      // TODO: The default sex value should probably be the heterogametic sex,\n      // i.e. whichever sex has allosomes that differ in morphology.\n      // In mammals and most insects that is the male.\n      // However, in birds and reptiles, that is female.\n      ideo.config.sex = 'male';\n    }\n    if (ideo.config.ploidy === 2 && !ideo.config.ancestors) {\n      ideo.config.ancestors = {M: '#ffb6c1', P: '#add8e6'};\n      ideo.config.ploidyDesc = 'MP';\n    }\n  }\n}\n\nfunction configureHeight(ideo) {\n  var container, rect, chrHeight;\n\n  if (!ideo.config.chrHeight) {\n    container = ideo.config.container;\n    rect = document.querySelector(container).getBoundingClientRect();\n\n    if (ideo.config.orientation === 'vertical') {\n      chrHeight = rect.height;\n    } else {\n      chrHeight = rect.width;\n    }\n\n    if (container === 'body' || chrHeight === 0) chrHeight = 400;\n    ideo.config.chrHeight = chrHeight;\n  }\n}\n\nfunction configureWidth(ideo) {\n  var chrWidth, chrHeight;\n\n  if (!ideo.config.chrWidth) {\n    chrWidth = 10;\n    chrHeight = ideo.config.chrHeight;\n\n    if (chrHeight < 900 && chrHeight > 500) {\n      chrWidth = Math.round(chrHeight / 40);\n    } else if (chrHeight >= 900) {\n      chrWidth = Math.round(chrHeight / 45);\n    }\n    ideo.config.chrWidth = chrWidth;\n  }\n}\n\nfunction configureMargin(ideo) {\n  if (ideo.config.geometry && ideo.config.geometry === 'collinear') {\n    if ('chrMargin' in ideo.config === false) {\n      ideo.config.chrMargin = 0;\n    }\n    return;\n  }\n  if (!ideo.config.chrMargin) {\n    if (ideo.config.ploidy === 1) {\n      ideo.config.chrMargin = 10;\n    } else {\n      // Defaults polyploid chromosomes to relatively small interchromatid gap\n      ideo.config.chrMargin = Math.round(ideo.config.chrWidth / 4);\n    }\n  }\n  if (ideo.config.showBandLabels) ideo.config.chrMargin += 20;\n}\n\nfunction configureBump(ideo) {\n  ideo.bump = Math.round(ideo.config.chrHeight / 125);\n  ideo.adjustedBump = false;\n  if (ideo.config.chrHeight < 200) {\n    ideo.adjustedBump = true;\n    ideo.bump = 4;\n  }\n}\n\nfunction configureSingleChromosome(config, ideo) {\n  if (config.chromosome) {\n    ideo.config.chromosomes = [config.chromosome];\n    if ('showBandLabels' in config === false) {\n      ideo.config.showBandLabels = true;\n    }\n    if ('rotatable' in config === false) ideo.config.rotatable = false;\n  }\n}\n\nfunction configureOrganisms(ideo) {\n  ideo.organisms = Object.assign({}, organismMetadata);\n  ideo.organismsWithBands = Object.assign({}, ideo.organisms);\n}\n\nfunction configureCallbacks(config, ideo) {\n  if (config.onLoad) ideo.onLoadCallback = config.onLoad;\n  if (config.onLoadAnnots) ideo.onLoadAnnotsCallback = config.onLoadAnnots;\n  if (config.onDrawAnnots) ideo.onDrawAnnotsCallback = config.onDrawAnnots;\n  if (config.onBrushMove) ideo.onBrushMoveCallback = config.onBrushMove;\n  if (config.onCursorMove) ideo.onCursorMoveCallback = config.onCursorMove;\n  if (config.onDidRotate) ideo.onDidRotateCallback = config.onDidRotate;\n  if (config.onWillShowAnnotTooltip) {\n    ideo.onWillShowAnnotTooltipCallback = config.onWillShowAnnotTooltip;\n  }\n  if (config.onClickAnnot) {\n    ideo.onClickAnnotCallback = config.onClickAnnot;\n  }\n}\n\nfunction configureMiscellaneous(ideo) {\n  ideo.chromosomesArray = [];\n  ideo.coordinateSystem = 'iscn';\n  ideo.maxLength = {bp: 0, iscn: 0};\n  ideo.chromosomes = {};\n  ideo.numChromosomes = 0;\n  if (!ideo.config.debug) ideo.config.debug = false;\n  if (!ideo.config.dataDir) ideo.config.dataDir = ideo.getDataDir();\n  if (!ideo.config.container) ideo.config.container = 'body';\n  ideo.selector = ideo.config.container + ' #_ideogram';\n  if (!ideo.config.resolution) ideo.config.resolution = '';\n  if (!ideo.config.orientation) ideo.config.orientation = 'vertical';\n  if (!ideo.config.brush) ideo.config.brush = null;\n  if (!ideo.config.rows) ideo.config.rows = 1;\n  if ('showChromosomeLabels' in ideo.config === false) {\n    ideo.config.showChromosomeLabels = true;\n  }\n  if (!ideo.config.showNonNuclearChromosomes) {\n    ideo.config.showNonNuclearChromosomes = false;\n  }\n  if (!ideo.config.chromosomeScale) {\n    ideo.config.chromosomeScale = 'absolute';\n  }\n}\n\nfunction configureBands(ideo) {\n  if (!ideo.config.showBandLabels) ideo.config.showBandLabels = false;\n\n  if ('showFullyBanded' in ideo.config === false) {\n    ideo.config.showFullyBanded = true;\n  }\n\n  ideo.bandsToShow = [];\n  ideo.bandData = {};\n}\n\nlet configuredCss = staticCss;\nfunction configureTextStyle(ideo) {\n  if (!ideo.config.chrLabelSize) {\n    ideo.config.chrLabelSize = 9;\n    return;\n  }\n\n  const size = ideo.config.chrLabelSize;\n  configuredCss += `#_ideogram text {font-size: ${size}px}`;\n}\n\n/**\n * High-level helper method for Ideogram constructor.\n *\n * @param config Configuration object.  Enables setting Ideogram properties.\n *\n * Docs: https://github.com/eweitz/ideogram/blob/master/api.md\n */\nfunction configure(config) {\n  // Clone the config object, to allow multiple instantiations\n  // without picking up prior ideogram's settings\n  this.config = JSON.parse(JSON.stringify(config));\n\n  configureMiscellaneous(this);\n  configurePloidy(this);\n  configureBands(this);\n  configureHeight(this);\n  configureWidth(this);\n  configureMargin(this);\n  configureCallbacks(config, this);\n  configureOrganisms(this);\n  configureBump(this);\n  configureSingleChromosome(config, this);\n  configureTextStyle(this);\n  this.initAnnotSettings();\n  if (!this.config.geometry || this.config.geometry === 'parallel') {\n    this.config.chrMargin += this.config.chrWidth;\n    if (this.config.annotationsLayout === 'heatmap') {\n      this.config.chrMargin += this.config.annotTracksHeight;\n    } else {\n      this.config.chrMargin += this.config.annotTracksHeight * 2;\n    }\n  }\n  this.init();\n}\n\nexport {configure, configuredCss};\n","/**\n * @fileoverview Functions for collinear chromosomes.\n * Collinear chromosomes form a line together, unlike the default parallel\n * geometry.\n */\n\nimport {d3} from './lib';\n\nfunction labelGenomes(ideo) {\n\n  ideo.config.taxids.forEach((taxid, i) => {\n    var org = ideo.organisms[taxid];\n    // var commonName = slug(org.commonName);\n    var scientificName = org.scientificName;\n    d3.select(ideo.selector)\n      .append('text')\n      .attr('class', 'genomeLabel italic')\n      .attr('x', 50 + 200 * i)\n      .attr('y', 10)\n      .text(scientificName)\n      .attr('text-anchor', 'middle');\n  });\n}\n\n/**\n* Rearrange chromosomes from parallel vertical to collinear vertical\n*\n* Parallel vertical (as in https://eweitz.github.io/ideogram/human)\n* | | |\n*\n* Collinear vertical (as in https://eweitz.github.io/ideogram/orthologs?loci=2:150000000,5:20000000;3:100000000,10:80000000&org=homo-sapiens&org2=mus-musculus)\n* |\n* |\n* |\n*/\nfunction rearrangeChromosomes(chrSets, yOffsets, x, ideo) {\n  var i, chrSet, y, chrLabelX, adjustedX, chr, taxid, orgIndex,\n    config = ideo.config,\n    chrLabelSize = config.chrLabelSize;\n\n  for (i = 0; i < chrSets.length; i++) {\n    chrSet = chrSets[i];\n    y = yOffsets[i] + 23 - chrLabelSize;\n\n    chr = ideo.chromosomesArray[i];\n    taxid = chr.id.split('-')[1];\n    orgIndex = ideo.config.taxids.indexOf(taxid);\n    adjustedX = x - orgIndex * 200 - 30;\n    if (orgIndex === 0) {\n      chrLabelX = -34;\n      adjustedX += ideo.config.chrWidth * 2 - 16;\n    } else {\n      chrLabelX = ideo.config.chrWidth * 2 - 24;\n    }\n\n    if (config.showChromosomeLabels) {\n      const labelSpan = chrSet.querySelector('.chrLabel > tspan');\n      labelSpan.setAttribute('x', chrLabelX);\n      labelSpan.setAttribute('dy', chrLabelSize - 8);\n      chrSet.querySelector('.chrLabel').setAttribute('text-anchor', 'start');\n    }\n    chrSet.setAttribute(\n      'transform', 'rotate(90) translate(' + y + ',' + adjustedX + ')'\n    );\n    chrSet.querySelector('.chromosome').setAttribute(\n      'transform', 'translate(-13, 10)'\n    );\n  }\n\n  labelGenomes(ideo);\n}\n\n/**\n* Get pixel coordinates to use for rearrangement\n*/\nfunction getyOffsets(chrSets, ideo) {\n  var yOffsets, i, index, chr, prevChr, y, prevWidth, prevY, yBump, taxid,\n    seenTaxids = {};\n\n  yOffsets = [];\n  for (i = 0; i < chrSets.length; i++) {\n    chr = ideo.chromosomesArray[i];\n    taxid = chr.id.split('-')[1];\n    index = (i === 0) ? i : i - 1;\n    prevChr = ideo.chromosomesArray[index];\n    if (i === 0 || taxid in seenTaxids === false) {\n      y = 20;\n      seenTaxids[taxid] = 1;\n    } else {\n      prevWidth = prevChr.width;\n      prevY = yOffsets[index];\n      yBump = (ideo.config.showChromosomeLabels ? 0 : 2);\n      y = prevY + prevWidth + yBump + ideo.config.chrMargin;\n    }\n    yOffsets.push(y);\n  }\n\n  return yOffsets;\n}\n\nfunction collinearizeVerticalChromosomes(ideo) {\n  var chrSets, yOffsets, x, height, width,\n    config = ideo.config;\n\n  ideo.config.annotLabelHeight = 12;\n  // var annotLabelHeight = ideo.config.annotLabelHeight;\n\n  if ('demarcateCollinearChromosomes' in ideo.config === false) {\n    ideo.config.demarcateCollinearChromosomes = true;\n  }\n\n  chrSets = document.querySelectorAll('.chromosome-set');\n\n  x = -40;\n\n  yOffsets = getyOffsets(chrSets, ideo);\n  rearrangeChromosomes(chrSets, yOffsets, x, ideo);\n\n  width = Math.round(yOffsets.slice(-1)[0] + 70);\n\n  if (config.multiorganism) {\n    height *= 8;\n    var maxHeight = 0;\n    yOffsets.forEach(d => {\n      if (d > maxHeight) maxHeight = d;\n    });\n    height = maxHeight + 30;\n  } else {\n    height = xOffsets.slice(-1)[0] + 30;\n  }\n\n  d3.select(ideo.selector)\n    .attr('height', height)\n    .attr('width', width);\n\n  d3.select('#_ideogramTrackLabelContainer').remove();\n  d3.select('#_ideogramInnerWrap')\n    .insert('div', ':first-child')\n    .attr('id', '_ideogramTrackLabelContainer')\n    .style('position', 'absolute');\n}\n\nexport default collinearizeVerticalChromosomes;\n","/**\n * @fileoverview Functions for collinear chromosomes.\n * Collinear chromosomes form a line together, unlike the default parallel\n * geometry.\n */\n\nimport {d3} from './lib';\nimport collinearizeVerticalChromosomes from './collinear-vertical';\n\nfunction labelGenomes(ideo) {\n\n  ideo.config.taxids.forEach((taxid, i) => {\n    var org = ideo.organisms[taxid];\n    var config = ideo.config;\n    // var commonName = slug(org.commonName);\n    var scientificName = org.scientificName;\n    d3.select(ideo.selector)\n      .append('text')\n      .attr('class', 'genomeLabel italic')\n      .attr('x', 5)\n      .attr('y', config.chrLabelSize + (200 + (3 * config.chrWidth)) * i)\n      .text(scientificName);\n  });\n}\n\n/**\n* Rearrange chromosomes from parallel horizontal to collinear horizontal\n*\n* Parallel horizontal (as in https://eweitz.github.io/ideogram/mouse)\n*     ---\n*     ---\n*     ---\n*\n* Collinear horizontal (as in https://eweitz.github.io/ideogram/geometry-collinear):\n*     --- --- ---\n*/\nfunction rearrangeChromosomes(chrSets, xOffsets, y, ideo) {\n  var i, chr, chrSet, taxid, x, adjustedY, orgIndex, chrLabelY,\n    config = ideo.config,\n    chrWidth = config.chrWidth,\n    chrLabelSize = config.chrLabelSize;\n\n  for (i = 0; i < chrSets.length; i++) {\n    chrSet = chrSets[i];\n    x = xOffsets[i];\n\n    chr = ideo.chromosomesArray[i];\n    taxid = chr.id.split('-')[1];\n    orgIndex = config.taxids.indexOf(taxid);\n    adjustedY = y + orgIndex * 200;\n    if (orgIndex === 0 && ideo.config.multiorganism) {\n      chrLabelY = chrLabelSize - 4;\n      adjustedY += chrWidth * 2 + chrLabelSize;\n    } else {\n      chrLabelY = chrWidth * 2 + chrLabelSize + 2;\n    }\n\n    if (ideo.config.showChromosomeLabels) {\n      chrSet.querySelector('.chrLabel').setAttribute('y', chrLabelY);\n      chrSet.querySelector('.chrLabel').setAttribute('text-anchor', 'middle');\n    }\n    chrSet.setAttribute('transform', 'translate(' + x + ',' + adjustedY + ')');\n    chrSet.querySelector('.chromosome').setAttribute(\n      'transform', 'translate(-13, 10)'\n    );\n  }\n\n  if (config.multiorganism) {\n    labelGenomes(ideo);\n  }\n}\n\n/**\n* Get pixel coordinates to use for rearrangement\n*/\nfunction getXOffsets(chrSets, ideo) {\n  var xOffsets, i, index, chr, prevChr, x, prevWidth, prevX, xBump, taxid,\n    seenTaxids = {};\n\n  xOffsets = [];\n  for (i = 0; i < chrSets.length; i++) {\n    chr = ideo.chromosomesArray[i];\n    taxid = chr.id.split('-')[1];\n    index = (i === 0) ? i : i - 1;\n    prevChr = ideo.chromosomesArray[index];\n    if (i === 0 || taxid in seenTaxids === false) {\n      x = 20;\n      seenTaxids[taxid] = 1;\n    } else {\n      prevWidth = prevChr.width;\n      prevX = xOffsets[index];\n      xBump = (ideo.config.showChromosomeLabels ? 0 : 2);\n      x = prevX + prevWidth + xBump + ideo.config.chrMargin;\n    }\n    xOffsets.push(x);\n  }\n\n  return xOffsets;\n}\n\n// /**\n//  * Track number of chromosomes in preceding organisms.\n//  * Adds an instance variable to the ideogram object to offset\n//  * chromosome indices.  Needed for multiorganism collinear ideograms.\n//  */\n// function setTaxidChrOffsets(ideo) {\n//   var taxidChrOffsets, taxidChrOffset;\n\n//   taxidChrOffsets = {};\n\n//   taxidChrOffset = 0;\n//   ideo.config.organism.forEach((org) => {\n//     var taxid, numChrs;\n//     taxid = ideo.getTaxid(org);\n//     taxidChrOffsets[taxid] = taxidChrOffset;\n//     numChrs = Object.keys(ideo.chromosomes[taxid]).length;\n//     taxidChrOffset += numChrs;\n//   });\n\n//   ideo.taxidChrOffsets = taxidChrOffsets;\n// }\n\n// /**\n//  * Change chromosome indices for multiorganism collinear ideograms\n//  * This is needed to account for x-offsets.\n//  */\n// function adjustChrIndex(ideo) {\n//   setTaxidChrOffsets(ideo);\n\n//   ideo.chromosomesArray.map((chr) => {\n//     var taxid = chr.id.split('-')[1];\n//     var taxidChrOffset = ideo.taxidChrOffsets[taxid];\n//     chr.chrIndex -= taxidChrOffset;\n//     ideo.chromosomes[taxid][chr.name].chrIndex = chr.chrIndex;\n//   });\n// }\n\nfunction collinearizeChromosomes(ideo) {\n  var chrSets, xOffsets, y, height, width,\n    config = ideo.config,\n    annotHeight = config.annotationHeight || 0;\n\n  if (config.orientation === 'vertical') {\n    collinearizeVerticalChromosomes(ideo);\n    return;\n  }\n\n  // if (config.multiorganism) adjustChrIndex(ideo);\n\n  ideo.config.annotLabelHeight = 12;\n  var annotLabelHeight = ideo.config.annotLabelHeight;\n\n  if ('demarcateCollinearChromosomes' in ideo.config === false) {\n    ideo.config.demarcateCollinearChromosomes = true;\n  }\n\n  chrSets = document.querySelectorAll('.chromosome-set');\n\n  y = (\n    (config.numAnnotTracks * (annotHeight + annotLabelHeight + 4)) -\n    config.chrWidth + 1\n  );\n\n  xOffsets = getXOffsets(chrSets, ideo);\n  rearrangeChromosomes(chrSets, xOffsets, y, ideo);\n\n  height = y + config.chrWidth * 2 + 20;\n\n  if (config.multiorganism) {\n    height *= 8;\n    var maxWidth = 0;\n    xOffsets.forEach(d => {\n      if (d > maxWidth) maxWidth = d;\n    });\n    width = maxWidth + 20;\n  } else {\n    width = xOffsets.slice(-1)[0] + 20;\n  }\n\n  d3.select(ideo.selector)\n    .attr('width', width)\n    .attr('height', height);\n\n  d3.select('#_ideogramTrackLabelContainer').remove();\n  d3.select('#_ideogramInnerWrap')\n    .insert('div', ':first-child')\n    .attr('id', '_ideogramTrackLabelContainer')\n    .style('position', 'absolute');\n}\n\nexport default collinearizeChromosomes;\n","import {d3} from '../lib';\nimport collinearizeChromosomes from '../collinear';\n\nfunction processLabels(config, ideo) {\n  var i, chrID, t0C, t1C;\n\n  if (config.showBandLabels === true) {\n    t0C = new Date().getTime();\n    ideo.hideUnshownBandLabels();\n    t1C = new Date().getTime();\n    if (config.debug) {\n      console.log('Time in showing bands: ' + (t1C - t0C) + ' ms');\n    }\n\n    if (config.orientation === 'vertical') {\n      for (i = 0; i < ideo.chromosomesArray.length; i++) {\n        chrID = '#' + ideo.chromosomesArray[i].id;\n        ideo.rotateChromosomeLabels(d3.select(chrID), i);\n      }\n    }\n  }\n\n  if (config.showChromosomeLabels === true) {\n    ideo.drawChromosomeLabels(ideo.chromosomes);\n  }\n}\n\nfunction processAnnots(ideo) {\n  if (typeof ideo.timeout !== 'undefined') window.clearTimeout(ideo.timeout);\n\n  ideo.rawAnnots = ideo.setOriginalTrackIndexes(ideo.rawAnnots);\n\n  if (ideo.config.annotationsDisplayedTracks) {\n    ideo.annots =\n      ideo.updateDisplayedTracks(ideo.config.annotationsDisplayedTracks);\n  } else {\n    ideo.annots = ideo.processAnnotData(ideo.rawAnnots);\n    if (ideo.config.filterable) ideo.initCrossFilter();\n    ideo.drawProcessedAnnots(ideo.annots);\n  }\n}\n\n/**\n * Load (potentially large) annotation dataset, then process it.\n */\nfunction waitForAndProcessAnnots(ideo) {\n  if (ideo.rawAnnots) {\n    processAnnots(ideo);\n  } else {\n    (function checkAnnotData() {\n      ideo.timeout = setTimeout(function() {\n        if (\n          !ideo.rawAnnots ||\n          (ideo.rawAnnots && typeof ideo.rawAnnots.then !== 'undefined')\n        ) {\n          // Ensure rawAnnots is defined and not a Promise (not \"then\"-able)\n          checkAnnotData();\n        } else {\n          processAnnots(ideo);\n        }\n      }, 50);\n    })();\n  }\n}\n\nfunction reportDebugTimings(config, t0, t0A) {\n\n  var t1A = new Date().getTime();\n  if (config.debug) {\n    console.log('Time in drawChromosome: ' + (t1A - t0A) + ' ms');\n  }\n\n  var t1 = new Date().getTime();\n  if (config.debug) {\n    console.log('Time constructing ideogram: ' + (t1 - t0) + ' ms');\n  }\n}\n\n/**\n * Completes high-level initialization.\n * Draws chromosomes and band labels, rotating as needed;\n * processes and draws annotations;\n * creates brush, emits notification of load completion, etc.\n */\nfunction finishInit(t0) {\n  var t0A = new Date().getTime(),\n    ideo = this,\n    config = ideo.config,\n    confAnnots = config.annotations;\n\n  ideo.initDrawChromosomes();\n\n  if (config.annotationsPath) waitForAndProcessAnnots(ideo);\n\n  processLabels(config, ideo);\n\n  // Create a brush or a click cursor if specified\n  if (config.brush) ideo.createBrush(config.brush);\n  else if (config.cursorPosition) ideo.createClickCursor(config.cursorPosition);\n\n  if (confAnnots) {\n    if (Array.isArray(confAnnots)) {\n      ideo.drawAnnots(confAnnots);\n    } else {\n      // Enable client-side-defined annotations to be formatted\n      // like the wider variety of server-side-defined annotations.\n      // Supports https://github.com/eweitz/ideogram/issues/137\n      ideo.rawAnnots = confAnnots;\n      ideo.afterRawAnnots();\n      processAnnots(ideo);\n    }\n  }\n\n  reportDebugTimings(config, t0, t0A);\n\n  ideo.setOverflowScroll();\n\n  if (config.geometry === 'collinear') collinearizeChromosomes(ideo);\n\n  if (ideo.onLoadCallback) ideo.onLoadCallback();\n}\n\nexport {finishInit};\n","export class Ploidy {\n\n  constructor(config) {\n    this._config = config;\n    this._description = this._normalize(this._config.ploidyDesc);\n  }\n\n  // Get number of chromosomes in a chromosome set\n  getChromosomesNumber(setIndex) {\n    if (this._config.ploidyDesc) {\n      var chrSetCode = this._config.ploidyDesc[setIndex];\n      if (chrSetCode instanceof Object) {\n        return Object.keys(chrSetCode)[0].length;\n      } else {\n        return chrSetCode.length;\n      }\n    } else {\n      return this._config.ploidy || 1;\n    }\n  }\n\n  // Normalize use defined description\n  _normalize(description) {\n    var key, descValue,\n      normalized = [];\n\n    if (!description) return description;\n\n    // Loop through description and normalize\n    for (key in description) {\n      descValue = description[key];\n      if (typeof descValue === 'string') {\n        if (this._config.orientation === 'vertical') {\n          descValue = descValue.split('').reverse();\n        }\n        normalized.push({\n          ancestors: descValue,\n          existence: this._getexistenceArray(descValue.length)\n        });\n      } else {\n        normalized.push({\n          ancestors: Object.keys(descValue)[0],\n          existence: descValue[Object.keys(descValue)[0]]\n        });\n      }\n    }\n\n    return normalized;\n  }\n\n  // Get array filled by '11' elements\n  _getexistenceArray(length) {\n    var array = [];\n\n    for (var i = 0; i < length; i++) {\n      array.push('11');\n    }\n\n    return array;\n  }\n\n  getSetSize(chrSetIndex) {\n    if (this._description) {\n      return this._description[chrSetIndex].ancestors.length;\n    } else {\n      return 1;\n    }\n  }\n\n  // Get ancestor letter\n  getAncestor(chrSetIndex, chrIndex) {\n    if (this._description) {\n      return this._description[chrSetIndex].ancestors[chrIndex];\n    } else {\n      return '';\n    }\n  }\n\n  // Check if chromosome's arm should be rendered.\n  // If no description was provided, method returns true and\n  // something another depending on user provided description.\n  exists(chrSetIndex, chrIndex, armIndex) {\n    if (this._description) {\n      var desc =\n        this._description[chrSetIndex].existence[chrIndex][armIndex];\n      return Number(desc) > 0;\n    } else {\n      return true;\n    }\n  }\n\n}\n","import {d3} from '../lib';\n\n/**\n * Chromosome's view utility class\n */\nexport class ChromosomeUtil {\n\n  constructor(node) {\n    this._node = node;\n  }\n\n  getLabel() {\n    var label =\n      d3\n        .select(this._node.parentNode)\n        .select('text.chrLabel')\n        .text();\n    return label;\n  }\n\n  /**\n   * Get chromosome set label\n   */\n  getSetLabel() {\n    var setLabel =\n      d3\n        .select(this._node.parentNode)\n        .select('text.chrSetLabel')\n        .text();\n    return setLabel;\n  }\n}\n","import {d3} from '../lib';\nimport {ChromosomeUtil} from './../views/chromosome-util';\n\nclass Layout {\n\n  constructor(config, ideo) {\n    this._config = config;\n    this._ideo = ideo;\n    this._ploidy = this._ideo._ploidy;\n    this._translate = undefined;\n\n    if ('chrSetMargin' in config) {\n      this.chrSetMargin = config.chrSetMargin;\n    } else {\n      var chrMargin = this._config.chrMargin;\n      this.chrSetMargin = (this._config.ploidy > 1 ? chrMargin : 0);\n    }\n\n    // Chromosome band's size.\n    this._tickSize = 8;\n\n    // Chromosome rotation state.\n    this._isRotated = false;\n  }\n\n  // Get chart left margin\n  _getLeftMargin() {\n    return this.margin.left;\n  }\n\n  // Get rotated chromosome y scale\n  _getYScale() {\n    // 20 is width of rotated chromosome.\n    return 20 / this._config.chrWidth;\n  }\n\n  // Get chromosome labels\n  getChromosomeLabels(chrElement) {\n    var util = new ChromosomeUtil(chrElement),\n      labels = [];\n\n    if (this._ideo.config.ploidy > 1) {\n      labels.push(util.getSetLabel());\n    }\n    labels.push(util.getLabel());\n\n    return labels.filter(function(d) {\n      return d.length > 0;\n    });\n  }\n\n  getChromosomeBandLabelTranslate(band) {\n    var x, y, translate,\n      ideo = this._ideo,\n      tickSize = this._tickSize,\n      orientation = ideo.config.orientation;\n\n    if (orientation === 'vertical') {\n      x = tickSize;\n      y = ideo.round(2 + band.px.start + band.px.width / 2);\n      translate = 'rotate(-90)translate(' + x + ',' + y + ')';\n    } else if (orientation === 'horizontal') {\n      x = ideo.round(-tickSize + band.px.start + band.px.width / 2);\n      y = -10;\n      translate = 'translate(' + x + ',' + y + ')';\n    }\n\n    return {\n      x: x,\n      y: y,\n      translate: translate\n    };\n  }\n\n  didRotate(chrIndex, chrElement) {\n    var ideo, taxid, chrName, bands, chrModel, oldWidth,\n      chrSetElement, transform, scale, scaleRE;\n\n    ideo = this._ideo;\n    taxid = ideo.config.taxid;\n    chrName = chrElement.id.split('-')[0].replace('chr', '');\n    chrModel = ideo.chromosomes[taxid][chrName];\n    bands = chrModel.bands;\n\n    chrSetElement = d3.select(chrElement.parentNode);\n    transform = chrSetElement.attr('transform');\n    scaleRE = /scale\\(.*\\)/;\n    scale = scaleRE.exec(transform);\n    transform = transform.replace(scale, '');\n    chrSetElement.attr('transform', transform);\n\n    oldWidth = chrModel.width;\n\n    chrModel = ideo.getChromosomeModel(bands, chrName, taxid, chrIndex);\n\n    chrModel.oldWidth = oldWidth;\n\n    ideo.chromosomes[taxid][chrName] = chrModel;\n    ideo.drawChromosome(chrModel);\n\n    ideo.handleRotateOnClick();\n\n    if (ideo.rawAnnots) {\n      if (ideo.displayedTrackIndexes) {\n        ideo.updateDisplayedTracks(ideo.displayedTrackIndexes);\n      } else {\n        ideo.annots = ideo.processAnnotData(ideo.rawAnnots);\n        ideo.drawProcessedAnnots(ideo.annots);\n\n        if (ideo.config.filterable) {\n          ideo.initCrossFilter();\n        }\n      }\n    }\n\n    if (ideo.config.showBandLabels === true) {\n      ideo.drawBandLabels(ideo.chromosomes);\n      ideo.hideUnshownBandLabels();\n    }\n\n    if (ideo.onDidRotateCallback) {\n      ideo.onDidRotateCallback(chrModel);\n    }\n  }\n\n  rotate(chrSetIndex, chrIndex, chrElement) {\n    var ideo, otherChrs, ideoBounds, labelSelectors;\n    ideo = this._ideo;\n\n    labelSelectors = (\n      ideo.selector + ' .chrSetLabel, ' + ideo.selector + ' .chrLabel'\n    );\n\n    ideoBounds = document.querySelector(ideo.selector).getBoundingClientRect();\n\n    // Find chromosomes which should be hidden\n    otherChrs = d3.selectAll(ideo.selector + ' g.chromosome')\n      .filter(function() {return this !== chrElement;});\n\n    if (this._isRotated) {\n\n      this._isRotated = false;\n\n      ideo.config.chrHeight = ideo.config.chrHeightOriginal;\n      ideo.config.chrWidth = ideo.config.chrWidthOriginal;\n      ideo.config.annotationHeight = ideo.config.annotationHeightOriginal;\n\n      // Rotate chromosome back\n      this.rotateBack(chrSetIndex, chrIndex, chrElement, function() {\n        // Show all other chromosomes and chromosome labels\n        otherChrs.style('display', null);\n        d3.selectAll(labelSelectors).style('display', null);\n        ideo._layout.didRotate(chrIndex, chrElement);\n      });\n\n    } else {\n\n      this._isRotated = true;\n\n      // Hide all other chromosomes and chromosome labels\n      otherChrs.style('display', 'none');\n      d3.selectAll(labelSelectors).style('display', 'none');\n\n      // Rotate chromosome\n      this.rotateForward(chrSetIndex, chrIndex, chrElement, function() {\n\n        var chrHeight, elementLength, windowLength;\n\n        ideo.config.chrHeightOriginal = ideo.config.chrHeight;\n        ideo.config.chrWidthOriginal = ideo.config.chrWidth;\n        ideo.config.annotationHeightOriginal = ideo.config.annotationHeight;\n\n        const settingsGearWidth = 20;\n\n        if (ideo._layout._class === 'VerticalLayout') {\n          elementLength = ideoBounds.width - settingsGearWidth;\n          windowLength = window.innerWidth - settingsGearWidth;\n        } else {\n          elementLength = ideoBounds.height - 10;\n          windowLength = window.innerHeight - 10;\n        }\n\n        // Set chromosome height to window length or ideogram element length,\n        // whichever is smaller.  This keeps whole chromosome viewable, while\n        // also ensuring the height doesn't exceed what the user specified.\n        if (windowLength < elementLength) {\n          chrHeight = windowLength;\n        } else {\n          chrHeight = elementLength;\n        }\n        chrHeight -= ideo.config.chrMargin * 2;\n        ideo.config.chrHeight = chrHeight;\n\n        // Account for chromosome label\n        // TODO: Make this dynamic, not hard-coded\n        ideo.config.chrWidth *= 2.3;\n\n        ideo.config.annotationHeight *= 1.7;\n\n        ideo._layout.didRotate(chrIndex, chrElement);\n      });\n    }\n  }\n\n  getChromosomeLabelClass() {\n    if (this._config.ploidy === 1) {\n      return 'chrLabel';\n    } else {\n      return 'chrSetLabel';\n    }\n  }\n\n  _getAdditionalOffset() {\n    var config = this._config;\n    var numTracks = config.annotationsNumTracks || config.numAnnotTracks || 1;\n    return (config.annotationHeight || 0) * numTracks;\n  }\n\n  _getChromosomeSetSize(chrSetIndex) {\n    // Get last chromosome set size.\n    var setSize = this._ploidy.getSetSize(chrSetIndex);\n\n    // Increase offset by last chromosome set size\n    return (\n      setSize * this._config.chrWidth * 2 + (this.chrSetMargin)\n    );\n  }\n\n  // Get chromosome set label anchor property\n  getChromosomeSetLabelAnchor() {\n    return 'middle';\n  }\n\n  // Get chromosome label y position.\n  getChromosomeLabelYPosition() {\n    return -5.5;\n  }\n\n  getChromosomeSetLabelYPosition(chrIndex) {\n    if (this._config.ploidy === 1) {\n      return this.getChromosomeLabelYPosition(chrIndex);\n    } else {\n      return -2 * this._config.chrWidth;\n    }\n  }\n\n}\n\nexport default Layout;\n","/**\n* @fileoverview Vertical layout class\n* Ideogram instances with vertical layout are oriented with each chromosome\n* starting at top and ending at bottom, and aligned as columns.\n*/\n\nimport {d3} from '../lib';\nimport Layout from './layout';\n\nclass VerticalLayout extends Layout {\n\n  constructor(config, ideo) {\n    super(config, ideo);\n    this._class = 'VerticalLayout';\n    // Layout margins\n    this.margin = {\n      top: 30,\n      left: 15\n    };\n  }\n\n  rotateForward(chrSetIndex, chrIndex, chrElement, callback) {\n    // TODO: Integrate chrSetIndex and chrIndex to support polyploid rotation.\n\n    var self = this;\n\n    var xOffset = 20;\n\n    var scale = this.getChromosomeScale(chrElement);\n\n    var transform =\n      'translate(' + xOffset + ', 25) ' + scale;\n\n    d3.select(chrElement.parentNode)\n      .transition()\n      .attr('transform', transform)\n      .on('end', callback);\n\n    // Append new chromosome labels\n    var labels = this.getChromosomeLabels(chrElement);\n    var y = (xOffset + self._config.chrWidth) * 1.3;\n    d3.select(this._ideo.getSvg())\n      .append('g')\n      .attr('class', 'tmp')\n      .selectAll('text')\n      .data(labels)\n      .enter()\n      .append('text')\n      .attr('class', function(d, i) {\n        return i === 0 && labels.length === 2 ? 'chrSetLabel' : null;\n      })\n      .attr('x', 0)\n      .attr('y', y).style('opacity', 0)\n      .text(String)\n      .transition()\n      .style('opacity', 1);\n\n    this._ideo.config.orientation = 'horizontal';\n  }\n\n  rotateBack(setIndex, chrIndex, chrElement, callback) {\n\n    var scale = this.getChromosomeScaleBack(chrElement);\n    var translate = this.getChromosomeSetTranslate(setIndex);\n\n    d3.select(chrElement.parentNode)\n      .transition()\n      .attr('transform', translate + ' ' + scale)\n      .on('end', callback);\n\n    d3.selectAll(this._ideo.selector + ' g.tmp')\n      .style('opacity', 0)\n      .remove();\n\n    this._ideo.config.orientation = 'vertical';\n  }\n\n  getHeight() {\n    return this._config.chrHeight + this.margin.top * 1.5;\n  }\n\n  getWidth() {\n    return '97%';\n  }\n\n  getChromosomeBandTickY1() {\n    return 2;\n  }\n\n  getChromosomeBandTickY2() {\n    return 10;\n  }\n\n  getChromosomeSetLabelTranslate() {\n    return 'rotate(-90)';\n  }\n\n  getChromosomeBandLabelAnchor() {\n    return null;\n  }\n\n  getChromosomeScale(chrElement) {\n    var ideoBox, chrBox, scaleX, scaleY;\n\n    ideoBox = d3.select(this._ideo.selector).node().getBoundingClientRect();\n    chrBox = chrElement.getBoundingClientRect();\n\n    scaleX = (ideoBox.width / chrBox.height) * 0.97;\n    scaleY = this._getYScale();\n\n    return 'scale(' + scaleX + ', ' + scaleY + ')';\n  }\n\n  getChromosomeScaleBack(chrElement) {\n    var scale, scaleX, scaleY, chrName, chrModel, taxid, ideo, config;\n\n    ideo = this._ideo;\n    config = ideo.config;\n    taxid = config.taxid;\n\n    chrName = chrElement.id.split('-')[0].replace('chr', '');\n    chrModel = this._ideo.chromosomes[taxid][chrName];\n    scaleX = (chrModel.oldWidth / (config.chrHeight * 3)) * 0.97;\n    scaleY = 1 / this._getYScale();\n    scale = 'scale(' + scaleX + ', ' + scaleY + ')';\n    return scale;\n  }\n\n  getChromosomeSetTranslate(setIndex) {\n    var marginTop = this.margin.top;\n    var chromosomeSetYTranslate = this.getChromosomeSetYTranslate(setIndex);\n    return (\n      'rotate(90) ' +\n      'translate(' + marginTop + ', -' + chromosomeSetYTranslate + ')'\n    );\n  }\n\n  getChromosomeSetYTranslate(setIndex) {\n    // Get additional padding caused by annotation/histogram tracks\n    var pad = this._getAdditionalOffset(),\n      margin = this._config.chrMargin,\n      width = this._config.chrWidth,\n      translate;\n\n    // If no detailed description provided just use one formula for all cases\n    if (!this._config.ploidyDesc) {\n      // TODO:\n      // This part of code contains a lot magic numbers and if\n      // statements for exactly corresponing to original ideogram examples.\n      // But all this stuff should be removed. Calculation of translate\n      // should be a simple formula applied for all cases listed below.\n      // Now they are diffirent because of Layout:_getAdditionalOffset do\n      // not meet for cases when no annotation, when annotation exists and\n      // when histogram used\n\n      if (this._config.annotationsLayout === 'histogram') {\n        var barWidth = this._ideo.config.barWidth;\n        return margin + setIndex * (margin + width + 3) + barWidth * 2;\n      } else {\n        translate = width + setIndex * (margin + width) + pad * 2;\n        if (pad > 0) {\n          return translate;\n        } else {\n          return translate + 4 + (2 * setIndex);\n        }\n      }\n    }\n\n    // If detailed description provided start to calculate offsets\n    // for each chromosome set separately. This should be done only once\n    if (!this._translate) {\n      // First offset equals to zero\n      this._translate = [this._ploidy.getSetSize(0) * width * 2];\n      var prevTranslate;\n      // Loop through description set\n      for (var i = 1; i < this._config.ploidyDesc.length; i++) {\n        prevTranslate = this._translate[i - 1];\n        this._translate[i] = prevTranslate + this._getChromosomeSetSize(i - 1);\n      }\n    }\n\n    return this._translate[setIndex];\n  }\n\n  getChromosomeSetLabelXPosition() {\n    return (this._config.chrWidth * this._config.ploidy) / -2;\n  }\n\n  getChromosomeLabelXPosition() {\n    return this._config.chrWidth / -2;\n  }\n}\n\nexport default VerticalLayout;\n","/**\n* @fileoverview Horizontal layout class\n* Ideogram instances with horizontal layout are oriented with each chromosome\n* starting at left and ending at right, and aligned as rows.\n*/\n\nimport {d3} from '../lib';\nimport Layout from './layout';\n\nclass HorizontalLayout extends Layout {\n\n  constructor(config, ideo) {\n    super(config, ideo);\n    this._class = 'HorizontalLayout';\n    this.margin = {\n      left: 20,\n      top: 30\n    };\n  }\n\n  _getLeftMargin() {\n    var margin = Layout.prototype._getLeftMargin.call(this);\n    if (this._config.ploidy > 1) {\n      margin *= 1.8;\n    }\n\n    return margin;\n  }\n\n  rotateForward(setIndex, chrIndex, chrElement, callback) {\n\n    var xOffset, yOffset, transform, labels;\n\n    xOffset = 30;\n\n    yOffset = xOffset + 7.5;\n\n    transform = (\n      'rotate(90) ' +\n      'translate(' + xOffset + ', -' + yOffset + ') '\n    );\n\n    d3.select(chrElement.parentNode)\n      .transition()\n      .attr('transform', transform)\n      .on('end', callback);\n\n    // Append new chromosome labels\n    labels = this.getChromosomeLabels(chrElement);\n    d3.select(this._ideo.getSvg())\n      .append('g')\n      .attr('class', 'tmp')\n      .selectAll('text')\n      .data(labels)\n      .enter()\n      .append('text')\n      .attr('class', function(d, i) {\n        return i === 0 && labels.length === 2 ? 'chrSetLabel' : null;\n      })\n      .attr('x', xOffset - 4)\n      .attr('y', function(d, i) {\n        return (i + 1 + labels.length % 2) * 12;\n      })\n      .style('text-anchor', 'middle')\n      .style('opacity', 0)\n      .text(String)\n      .transition()\n      .style('opacity', 1);\n\n    this._ideo.config.orientation = 'vertical';\n  }\n\n  rotateBack(setIndex, chrIndex, chrElement, callback) {\n    var translate = this.getChromosomeSetTranslate(setIndex);\n\n    d3.select(chrElement.parentNode)\n      .transition()\n      .attr('transform', translate)\n      .on('end', callback);\n\n    d3.selectAll(this._ideo.selector + ' g.tmp')\n      .style('opacity', 0)\n      .remove();\n\n    this._ideo.config.orientation = 'horizontal';\n  }\n\n  getHeight(taxid) {\n    if (typeof taxid === 'undefined') taxid = this._config.taxids[0];\n    // Get last chromosome set offset.\n    var numChromosomes = this._config.chromosomes[taxid].length;\n    var lastSetOffset = this.getChromosomeSetYTranslate(numChromosomes - 1);\n\n    // Get last chromosome set size.\n    var lastSetSize = this._getChromosomeSetSize(numChromosomes - 1);\n\n    // Increase offset by last chromosome set size\n    lastSetOffset += lastSetSize;\n\n    return lastSetOffset + this._getAdditionalOffset() * 2;\n  }\n\n  getWidth() {\n    return this._config.chrHeight + this.margin.top * 1.5;\n  }\n\n  getChromosomeSetLabelAnchor() {\n    return 'end';\n  }\n\n  getChromosomeBandLabelAnchor() {\n    return null;\n  }\n\n  getChromosomeBandTickY1() {\n    return 2;\n  }\n\n  getChromosomeBandTickY2() {\n    return 10;\n  }\n\n  getChromosomeSetLabelTranslate() {\n    return null;\n  }\n\n  getChromosomeSetTranslate(setIndex) {\n    var leftMargin = this._getLeftMargin();\n    var yTranslate = this.getChromosomeSetYTranslate(setIndex);\n    return 'translate(' + leftMargin + ', ' + yTranslate + ')';\n  }\n\n  getChromosomeSetYTranslate(setIndex) {\n    // If no detailed description provided just use one formula for all cases.\n    if (!this._config.ploidyDesc) {\n      return this._config.chrMargin * (setIndex + 1);\n    }\n\n    // Id detailed description provided start to calculate offsets\n    //  for each chromosome set separately. This should be done only once.\n    if (!this._translate) {\n      // First offset equals to zero.\n      this._translate = [1];\n\n      // Loop through description set\n      for (var i = 1; i < this._config.ploidyDesc.length; i++) {\n        this._translate[i] =\n          this._translate[i - 1] + this._getChromosomeSetSize(i - 1);\n      }\n    }\n\n    return this._translate[setIndex];\n  }\n\n  getChromosomeSetLabelXPosition(i) {\n    if (this._config.ploidy === 1) {\n      return this.getChromosomeLabelXPosition(i);\n    } else {\n      return -20;\n    }\n  }\n\n  getChromosomeSetLabelYPosition(i) {\n    var setSize = this._ploidy.getSetSize(i),\n      config = this._config,\n      chrMargin = config.chrMargin,\n      chrWidth = config.chrWidth,\n      y;\n\n    if (config.ploidy === 1) {\n      y = chrWidth / 2 + 3;\n    } else {\n      y = (setSize * chrMargin) / 2;\n    }\n\n    return y;\n  }\n\n  getChromosomeLabelXPosition() {\n    return -8;\n  }\n\n  getChromosomeLabelYPosition() {\n    return this._config.chrWidth;\n  }\n\n}\n\nexport default HorizontalLayout;\n","/**\n* @fileoverview Paired layout class\n* Ideograms with paired layout group each chromosome in a chromosome set.\n* This enables ploidy support beyond the default haploid; e.g. diploid genomes.\n*/\n\nimport Layout from './layout';\n\nclass PairedLayout extends Layout {\n\n  constructor(config, ideo) {\n    super(config, ideo);\n\n    this._class = 'PairedLayout';\n\n    this.margin = {\n      left: 30\n    };\n  }\n\n  getHeight() {\n    return this._config.chrHeight + this.margin.left * 1.5;\n  }\n\n  getWidth() {\n    return '97%';\n  }\n\n  getChromosomeBandTickY1(chrIndex) {\n    return chrIndex % 2 ? this._config.chrWidth : this._config.chrWidth * 2;\n  }\n\n  getChromosomeBandTickY2(chrIndex) {\n    var width = this._config.chrWidth;\n    return chrIndex % 2 ? width - this._tickSize : width * 2 + this._tickSize;\n  }\n\n  getChromosomeBandLabelAnchor(chrIndex) {\n    return chrIndex % 2 ? null : 'end';\n  }\n\n  getChromosomeBandLabelTranslate(band, chrIndex) {\n    var x = chrIndex % 2 ? 10 : -this._config.chrWidth - 10;\n    var y = this._ideo.round(band.px.start + band.px.width / 2) + 3;\n\n    return {\n      x: y,\n      y: y,\n      translate: 'rotate(-90) translate(' + x + ', ' + y + ')'\n    };\n  }\n\n  getChromosomeLabelXPosition() {\n    return -this._tickSize;\n  }\n\n  getChromosomeSetLabelXPosition() {\n    return this._config.chrWidth / -2;\n  }\n\n  getChromosomeSetLabelTranslate() {\n    return 'rotate(-90)';\n  }\n\n  getChromosomeSetTranslate(setIndex) {\n    var chromosomeSetYTranslate = this.getChromosomeSetYTranslate(setIndex);\n    return (\n      'rotate(90) ' +\n      'translate(' + this.margin.left + ', -' + chromosomeSetYTranslate + ')'\n    );\n  }\n\n  getChromosomeSetYTranslate(setIndex) {\n    return 200 * (setIndex + 1);\n  }\n\n}\n\nexport default PairedLayout;\n","import Layout from './layout';\n\nclass SmallLayout extends Layout {\n\n  constructor(config, ideo) {\n    super(config, ideo);\n\n    this._class = 'SmallLayout';\n\n    this.margin = {\n      left: 36.5,\n      top: 10\n    };\n\n    var taxid = this._ideo.getTaxid(this._ideo.config.organism);\n\n    this.chrs = config.chromosomes[taxid];\n    var numChrs = this.chrs.length;\n\n    // Number of chromosomes per row\n    this.chrsPerRow = Math.ceil(numChrs / config.rows);\n  }\n\n  // rotateForward(setIndex, chrIndex, chrElement, callback) {\n  //   var ideoBox =\n  //      d3.select(this._ideo.selector).node().getBoundingClientRect();\n  //   var chrBox = chrElement.getBoundingClientRect();\n  //\n  //   var scaleX = (ideoBox.width / chrBox.height) * 0.97;\n  //   var scaleY = this._getYScale();\n  //\n  //   transform = 'translate(5, 25) scale(' + scaleX + ', ' + scaleY + ')';\n  //\n  //   d3.select(chrElement.parentNode)\n  //     .transition()\n  //     .attr('transform', transform)\n  //     .on('end', callback);\n  // }\n  //\n  // rotateBack(setIndex, chrIndex, chrElement, callback) {\n  //   var translate = this.getChromosomeSetTranslate(setIndex);\n  //\n  //   d3.select(chrElement.parentNode)\n  //     .transition()\n  //     .attr('transform', translate)\n  //     .on('end', callback);\n  // }\n\n  /**\n   * eweitz 2020-04-13:\n   * This height metric is crude because it is calculated before\n   * the height (\"width\") of each chromosome is calculated.\n   *\n   * It calculates height by multiplying the max height of all chromosomes\n   * (specified in the Ideogram configuration object) by the number of rows.\n   * This ensures the ideogram height doesn't truncate in cases like dog\n   * (where chrX on the second row is longer than chr1 on the first), but it\n   * often leaves too much space on the second row, e.g. for human.\n   *\n   * Ideally, ideogram height would be cumulative height per row, plus top\n   * margin.  This would require calling getHeight _after_ all chromosomes\n   * have had their height (technically, chr.width) assigned.  See draft new\n   * getHeight method below this getHeight method.\n  */\n  getHeight() {\n    var config = this._config;\n    var chrHeight = config.chrHeight * 1.25;\n    return this._config.rows * (chrHeight + this.margin.top);\n  }\n\n  /**\n   * eweitz 2020-04-13:\n   * Draft refinement of getHeight.  See note in classic version above.\n   *\n   * Total height is cumulative height per row, plus top margin\n   */\n  // getHeight() {\n  //   let height = 0;\n  //   const rows = this._config.rows;\n  //   const chrEntries = Object.entries(this.chrs);\n\n  //   for (let i = 0; i < rows; i++) {\n  //     let rowHeight = 0;\n  //     // Starting and ending indexes of chromosomes of this row\n  //     const startIndex = this.chrsPerRow * i;\n  //     const endIndex = this.chrsPerRow * (i + 1) - 1;\n\n  //     for (let j = startIndex; j < endIndex; j++) {\n  //       const thisChrHeight = chrEntries[j][1].width;\n  //       if (thisChrHeight > rowHeight) {\n  //         rowHeight = thisChrHeight;\n  //       }\n  //     }\n  //     height += rowHeight + this.margin.top;\n  //   }\n\n  //   return height;\n  // }\n\n  getWidth() {\n    return '97%';\n  }\n\n  getChromosomeBandLabelTranslate() {\n\n  }\n\n  getChromosomeSetLabelTranslate() {\n    return 'rotate(-90)';\n  }\n\n  getChromosomeSetTranslate(setIndex) {\n    var xOffset, yOffset;\n\n    if (setIndex > this.chrsPerRow - 1) {\n      xOffset = this.margin.left + this._config.chrHeight * 1.3;\n      yOffset = this.getChromosomeSetYTranslate(setIndex - this.chrsPerRow);\n    } else {\n      xOffset = this.margin.left;\n      yOffset = this.getChromosomeSetYTranslate(setIndex);\n    }\n\n    return 'rotate(90) translate(' + xOffset + ', -' + yOffset + ')';\n  }\n\n  getChromosomeSetYTranslate(setIndex) {\n    // Get additional padding caused by annotation tracks\n    var additionalPadding = this._getAdditionalOffset() * 0.3;\n    // If no detailed description provided just use one formula for all cases\n    return (\n      this.margin.left * (setIndex) + this._config.chrWidth +\n      additionalPadding * 2 + additionalPadding * setIndex\n    );\n  }\n\n  getChromosomeSetLabelXPosition(setIndex) {\n    return (\n      ((this._ploidy.getSetSize(setIndex) * this._config.chrWidth + 20) / -2) +\n      (this._config.ploidy > 1 ? 0 : this._config.chrWidth)\n    );\n  }\n\n  getChromosomeLabelXPosition() {\n    return this._config.chrWidth / -2;\n  }\n\n}\n\nexport default SmallLayout;\n","import {d3} from '../lib';\nimport {Ploidy} from '../ploidy';\nimport {getLayout} from '../layouts/layout-adapter';\n\n/**\n * If ploidy description is a string, then convert it to the canonical\n * array format.  String ploidyDesc is used when depicting e.g. parental\n * origin each member of chromosome pair in a human genome.\n * See ploidy-basic.html for usage example.\n */\nfunction setPloidy(ideo) {\n  if (\n    'ploidyDesc' in ideo.config &&\n    typeof ideo.config.ploidyDesc === 'string'\n  ) {\n    var tmp = [];\n    for (var i = 0; i < ideo.numChromosomes; i++) {\n      tmp.push(ideo.config.ploidyDesc);\n    }\n    ideo.config.ploidyDesc = tmp;\n  }\n  // Organism ploidy description\n  ideo._ploidy = new Ploidy(ideo.config);\n}\n\nfunction getContainerSvgClass(ideo) {\n  var svgClass = '';\n  if (ideo.config.showChromosomeLabels) {\n    if (ideo.config.orientation === 'horizontal') {\n      svgClass += 'labeledLeft ';\n    } else {\n      svgClass += 'labeled ';\n    }\n  }\n\n  if (ideo.config.rotatable === false) {\n    svgClass += 'no-rotate ';\n  }\n\n  if (\n    ideo.config.annotationsLayout &&\n    ideo.config.annotationsLayout === 'overlay'\n  ) {\n    svgClass += 'faint';\n  }\n\n  return svgClass;\n}\n\n/**\n * Write tooltip div setup with default styling.\n */\nfunction writeTooltipContainer(ideo) {\n  d3.select(ideo.config.container + ' #_ideogramOuterWrap').append('div')\n    .attr('class', '_ideogramTooltip')\n    .attr('id', '_ideogramTooltip')\n    .style('opacity', 0)\n    .style('position', 'fixed')\n    .style('text-align', 'center')\n    .style('padding', '4px')\n    .style('font', '12px sans-serif')\n    .style('background', 'white')\n    .style('border', '1px solid black')\n    .style('border-radius', '5px')\n    .style('z-index', '9000');\n}\n\nfunction writeContainerDom(ideo) {\n\n  // Remove any previous container content\n  d3.selectAll(ideo.config.container + ' #_ideogramOuterWrap').remove();\n\n  d3.select(ideo.config.container)\n    .append('div')\n    .attr('id', '_ideogramOuterWrap')\n    .append('div')\n    .attr('id', '_ideogramTrackLabelContainer')\n    .style('position', 'absolute');\n\n  d3.select(ideo.config.container + ' #_ideogramOuterWrap').append('div')\n    .attr('id', '_ideogramMiddleWrap') // needed for overflow and scrolling\n    .style('position', 'relative')\n    .style('overflow-x', 'auto')\n    .style('transform', 'translateZ(0)') // add compositing layer for ideogram\n    .append('div')\n    .attr('id', '_ideogramInnerWrap') // needed for overflow and scrolling\n    .append('svg')\n    .attr('id', '_ideogram')\n    .attr('class', getContainerSvgClass(ideo))\n    .attr('width', ideo._layout.getWidth())\n    .attr('height', ideo._layout.getHeight())\n    .html(ideo.getBandColorGradients());\n}\n\n/**\n * Writes the HTML elements that contain this ideogram instance.\n */\nfunction writeContainer(t0) {\n  var ideo = this;\n\n  if (ideo.config.annotationsPath) {\n    ideo.fetchAnnots(ideo.config.annotationsPath);\n  }\n\n  setPloidy(ideo);\n\n  ideo._layout = getLayout(ideo);\n\n  writeContainerDom(ideo);\n\n  ideo.isOnlyIdeogram = document.querySelectorAll('#_ideogram').length === 1;\n  writeTooltipContainer(ideo);\n  ideo.finishInit(t0);\n}\n\nexport {writeContainer};\n","import VerticalLayout from './vertical-layout';\nimport HorizontalLayout from './horizontal-layout';\nimport PairedLayout from './paired-layout';\nimport SmallLayout from './small-layout';\n\nfunction getLayout(ideo) {\n  var config = ideo.config;\n\n  if ('perspective' in config && config.perspective === 'comparative') {\n    return new PairedLayout(config, ideo);\n  } else if ('rows' in config && config.rows > 1) {\n    return new SmallLayout(config, ideo);\n  } else if (config.orientation === 'vertical') {\n    return new VerticalLayout(config, ideo);\n  } else if (config.orientation === 'horizontal') {\n    return new HorizontalLayout(config, ideo);\n  } else {\n    return new VerticalLayout(config, ideo);\n  }\n}\n\nexport {getLayout};\n","import {hasNonGenBankAssembly} from '../lib';\n\nvar lastBandDataUrl = '';\n\nfunction getBandUrl(bandDataFileNames, taxid, ideo) {\n  return ideo.config.dataDir + bandDataFileNames[taxid];\n}\n\nfunction shouldFetchBands(bandDataFileNames, taxid, ideo) {\n  var bandDataUrl = getBandUrl(bandDataFileNames, taxid, ideo);\n  return (\n    !(typeof window.chrBands !== 'undefined' && lastBandDataUrl === '') ||\n    lastBandDataUrl !== bandDataUrl\n  ) &&\n  hasNonGenBankAssembly(ideo) &&\n  taxid in bandDataFileNames;\n}\n\nfunction setBandData(url, fileNames, chrBands, ideo) {\n  var taxid, fetchedTaxid, fileName;\n\n  // Ensures correct taxid is processed in response callback;\n  // using simply upstream 'taxid' variable gives the last\n  // *requested* taxid, which fails when dealing with multiple taxa.\n  for (taxid in fileNames) {\n    fileName = fileNames[taxid];\n    if (url.includes(fileName) && fileName !== '') {\n      fetchedTaxid = taxid;\n    }\n  }\n\n  ideo.bandData[fetchedTaxid] = chrBands;\n}\n\nfunction fetchBands(bandDataFileNames, taxid, t0, ideo) {\n  var bandDataUrl = getBandUrl(bandDataFileNames, taxid, ideo);\n\n  if (!ideo.numBandDataResponses) ideo.numBandDataResponses = 0;\n\n  return fetch(bandDataUrl)\n    .then(function(response) {\n      return response.json().then(function(rawBands) {\n        lastBandDataUrl = bandDataUrl;\n\n        delete window.chrBands; // Remove any previous chrBands variable\n        window.chrBands = rawBands.chrBands;\n\n        setBandData(response.url, bandDataFileNames, chrBands, ideo);\n      });\n    });\n}\n\nexport {shouldFetchBands, fetchBands};\n","/**\n * @fileoveriew Methods for initialization\n */\n\nimport {d3, slug} from '../lib';\nimport {configure} from './configure';\nimport {finishInit} from './finish-init';\nimport {writeContainer} from './write-container';\nimport {shouldFetchBands, fetchBands} from '../bands/fetch';\nimport {organismMetadata} from './organism-metadata';\n\nfunction isHeterogameticChromosome(chrModel, chrIndex, ideo) {\n  var ploidy = ideo.config.ploidy;\n  return (\n    'sex' in ideo.config &&\n      (\n        ploidy === 2 && ideo.sexChromosomes.index + 1 === chrIndex ||\n        ideo.config.sex === 'female' && chrModel.name === 'Y'\n      )\n  );\n}\n\nfunction prepareChromosomes(bandsArray, chrs, taxid, ideo) {\n  var j, bands, chromosome, chrModel, chrIndex;\n\n  for (j = 0; j < chrs.length; j++) {\n    chromosome = chrs[j];\n    if (typeof bandsArray !== 'undefined') bands = bandsArray[j];\n\n    chrIndex = j + ideo.config.taxids.indexOf(taxid);\n    chrModel = ideo.getChromosomeModel(bands, chromosome, taxid, chrIndex);\n\n    if (typeof chromosome !== 'string') {\n      chromosome = chromosome.name.split(' ').slice(-1)[0].replace('chr', '');\n    }\n\n    ideo.chromosomes[taxid][chromosome] = chrModel;\n    ideo.chromosomesArray.push(chrModel);\n\n    if (isHeterogameticChromosome(chrModel, j, ideo)) continue;\n\n    ideo.drawChromosome(chrModel);\n  }\n}\n\nfunction setCoordinateSystem(chrs, ideo) {\n  if (\n    typeof chrBands !== 'undefined' &&\n    chrs.length >= chrBands.length / 2\n  ) {\n    ideo.coordinateSystem = 'bp';\n  }\n}\n\n/**\n * Configures chromosome data and calls downstream chromosome drawing functions\n */\nfunction initDrawChromosomes() {\n  var taxid, i, chrs, bandsArray,\n    ideo = this,\n    taxids = ideo.config.taxids;\n\n  for (i = 0; i < taxids.length; i++) {\n    taxid = taxids[i];\n    chrs = ideo.config.chromosomes[taxid];\n\n    bandsArray = ideo.bandsArray[taxid];\n\n    setCoordinateSystem(chrs, ideo);\n\n    ideo.chromosomes[taxid] = {};\n    ideo.setSexChromosomes(chrs);\n\n    prepareChromosomes(bandsArray, chrs, taxid, ideo);\n\n    if (ideo.config.showBandLabels) ideo.drawBandLabels(ideo.chromosomes);\n    ideo.handleRotateOnClick();\n    ideo._gotChrModels = true; // Prevent issue with errant rat centromeres\n  }\n}\n\n/**\n * Attach any click handlers to rotate and toggle chromosomes\n */\nfunction handleRotateOnClick() {\n  var ideo = this;\n\n  if (!('rotatable' in ideo.config && ideo.config.rotatable === false)) {\n    d3.selectAll(ideo.selector + ' .chromosome').on('click', function() {\n      ideo.rotateAndToggleDisplay(this);\n    });\n  } else {\n    d3.selectAll(ideo.selector + ' .chromosome')\n      .style('cursor', 'default');\n  }\n}\n\n/**\n * Called when Ideogram has finished initializing.\n * Accounts for certain ideogram properties not being set until\n * asynchronous requests succeed, etc.\n */\nfunction onLoad() {\n  call(this.onLoadCallback);\n}\n\nfunction getBandFileName(taxid, accession, ideo) {\n  var organism = ideo.organisms[taxid];\n  var bandFileName = [slug(organism.scientificName)];\n  var assemblies = organism.assemblies;\n  var resolution = ideo.config.resolution;\n\n  if (accession !== assemblies.default) {\n    bandFileName.push(accession);\n  }\n  if (\n    taxid === '9606' &&\n    (accession in assemblies === 'false' &&\n      Object.values(assemblies).includes(config.assembly) ||\n      (resolution !== '' && resolution !== 850))\n  ) {\n    bandFileName.push(resolution);\n  }\n\n  bandFileName = bandFileName.join('-');\n\n  var fullyBandedTaxids = ['9606', '10090', '10116'];\n  if (fullyBandedTaxids.includes(taxid) && !ideo.config.showFullyBanded) {\n    bandFileName += '-no-bands';\n  }\n\n  bandFileName += '.json';\n\n  return bandFileName;\n}\n\nfunction getBandFileNames(taxid, bandFileNames, ideo) {\n  var organism, assemblies, accession, bandFileName,\n    config = ideo.config;\n\n  organism = ideo.organisms[taxid];\n\n  if (!config.assembly) ideo.config.assembly = 'default';\n\n  assemblies = organism.assemblies;\n\n  if (ideo.assemblyIsAccession()) {\n    accession = config.assembly;\n  } else {\n    accession = assemblies[config.assembly];\n  }\n\n  bandFileName = getBandFileName(taxid, accession, ideo);\n\n  if (taxid in ideo.organismsWithBands) {\n    bandFileNames[taxid] = bandFileName;\n  }\n  return bandFileNames;\n}\n\nfunction prepareContainer(taxid, bandFileNames, t0, ideo) {\n\n  if (shouldFetchBands(bandFileNames, taxid, ideo)) {\n    return fetchBands(bandFileNames, taxid, t0, ideo).then(function() {\n      return ideo.processBandData(taxid);\n    });\n  } else {\n    return new Promise(function(resolve) {\n      ideo.processBandData(taxid);\n      resolve([taxid, undefined]);\n    });\n  }\n}\n\nfunction initializeTaxids(ideo) {\n  return new Promise(function(resolve) {\n    if (typeof ideo.config.organism === 'number') {\n      // 'organism' is a taxid, e.g. 9606\n      var taxid = ideo.config.organism;\n      ideo.getOrganismFromEutils(taxid, function() {\n        ideo.getTaxids(resolve);\n      });\n    } else {\n      ideo.getTaxids(resolve);\n    }\n\n  });\n}\n\nfunction getBandsAndPrepareContainer(taxids, t0, ideo) {\n  var bandFileNames, i, taxid,\n    promises = [];\n\n  bandFileNames = {};\n  for (taxid in organismMetadata) {\n    bandFileNames[taxid] = '';\n  }\n\n  for (i = 0; i < taxids.length; i++) {\n    taxid = String(taxids[i]);\n    bandFileNames = getBandFileNames(taxid, bandFileNames, ideo);\n    promises.push(prepareContainer(taxid, bandFileNames, t0, ideo));\n  }\n\n  Promise.all(promises).then(function(taxidsAndBandsArrays) {\n    var taxidAndBandsArray, taxid, bandsArray;\n\n    for (i = 0; i < taxidsAndBandsArrays.length; i++) {\n      taxidAndBandsArray = taxidsAndBandsArrays[i];\n      taxid = taxidAndBandsArray[0];\n      bandsArray = taxidAndBandsArray[1];\n\n      if ('bandsArray' in ideo === false) {\n        ideo.bandsArray = {};\n      }\n\n      ideo.bandsArray[taxid] = bandsArray;\n    }\n    ideo.writeContainer(t0);\n  });\n}\n\n/**\n * Initializes an ideogram.\n * Sets some high-level properties based on instance configuration,\n * fetches band and annotation data if needed, and\n * writes an SVG element to the document to contain the ideogram\n */\n// Prevents race condition when init is called multiple times in\n// quick succession.\n// See https://github.com/eweitz/ideogram/pull/154.\nvar ideoNext = {};\nvar ideoQueued = {};\nvar ideoWait = {};\n\nfunction init(ideo) {\n  ideo = ideo || this;\n  var containerId = ideo.config.container;\n\n  if (ideoWait[containerId]) {\n    ideoQueued[containerId] = true;\n    ideoNext[containerId] = ideo;\n  } else {\n    ideoWait[containerId] = true;\n    initializeTaxids(ideo)\n      .then(function(taxids) {\n\n        var taxid = taxids[0];\n        ideo.config.taxid = taxid;\n        ideo.config.taxids = taxids;\n\n        var t0 = new Date().getTime();\n        getBandsAndPrepareContainer(taxids, t0, ideo);\n\n        ideoWait[containerId] = false;\n        if (ideoQueued[containerId]) {\n          ideoQueued[containerId] = false;\n          init(ideoNext[containerId]);\n        }\n      });\n  }\n}\n\nexport {\n  configure, initDrawChromosomes, handleRotateOnClick,\n  onLoad, init, finishInit, writeContainer\n};\n","/**\n * @fileoverview Parse raw Ideogram.js annotations from a BED file\n * BED documentation: https://genome.ucsc.edu/FAQ/FAQformat#format1\n */\n\nexport class BedParser {\n\n  constructor(bed, ideo) {\n    this.rawAnnots = this.parseBed(bed, ideo);\n  }\n\n  // http://stackoverflow.com/a/5624139\n  static componentToHex(c) {\n    var hex = parseInt(c, 10).toString(16);\n    return hex.length === 1 ? '0' + hex : hex;\n  }\n\n  static rgbToHex(r, g, b) {\n    return (\n      '#' +\n      BedParser.componentToHex(r) +\n      BedParser.componentToHex(g) +\n      BedParser.componentToHex(b)\n    );\n  }\n\n  parseGenomicCoordinates(columns, ucscStyle) {\n    var chr, start, stop, length;\n\n    // These three columns (i.e. fields) are required\n    chr = columns[0];\n    start = parseInt(columns[1], 10);\n    stop = parseInt(columns[2], 10);\n\n    length = stop - start;\n\n    if (ucscStyle) {\n      chr = chr.slice(3);\n    }\n\n    return [chr, start, stop, length];\n  }\n\n  /**\n   * Parses an annotation from a tab-separated line of a BED file\n   */\n  parseAnnotFromTsvLine(tsvLine, chrs, ucscStyle) {\n    var annot, chrIndex, chr, start, rgb, color, label,\n      columns = tsvLine.split(/\\s/g);\n\n    [chr, start, stop, length] =\n      this.parseGenomicCoordinates(columns, ucscStyle);\n\n    chrIndex = chrs.indexOf(chr);\n    if (chrIndex === -1) return [null, null];\n\n    annot = ['', start, length, 0];\n\n    if (columns.length >= 4) {\n      label = columns[3];\n      annot[0] = label;\n    }\n\n    if (columns.length >= 8) {\n      rgb = columns[8].split(',');\n      color = BedParser.rgbToHex(rgb[0], rgb[1], rgb[2]);\n      annot.push(color);\n    }\n\n    return [chrIndex, annot];\n  }\n\n  parseRawAnnots(annots, bedStartIndex, tsvLines, chrs) {\n    var i, line, chrIndex, annot, keys, rawAnnots, ucscStyle;\n\n    ucscStyle = true;\n    if (isNaN(parseInt(tsvLines[bedStartIndex], 10)) === false) {\n      ucscStyle = false;\n    }\n\n    for (i = bedStartIndex; i < tsvLines.length; i++) {\n      line = tsvLines[i];\n      [chrIndex, annot] = this.parseAnnotFromTsvLine(line, chrs, ucscStyle);\n      if (chrIndex !== null) annots[chrIndex].annots.push(annot);\n    }\n\n    keys = ['name', 'start', 'length', 'trackIndex'];\n    if (tsvLines[bedStartIndex].length >= 8) keys.push('color');\n\n    rawAnnots = {keys: keys, annots: annots};\n\n    return rawAnnots;\n  }\n\n  /**\n  * Parses a BED file, returns raw annotations\n  */\n  parseBed(bed, ideo) {\n    var i, chrs, chr, bedStartIndex, rawAnnots,\n      annots = [],\n      tsvLines = bed.split(/\\r\\n|\\n/);\n\n    chrs = Object.keys(ideo.chromosomes[ideo.config.taxid]);\n\n    for (i = 0; i < chrs.length; i++) {\n      chr = chrs[i];\n      annots.push({chr: chr, annots: []});\n    }\n\n    bedStartIndex = 0; // 1 if BED has header (i.e. track line), 0 otherwise\n    if (tsvLines[0].slice(0, 3) === 'chr' || isNaN(parseInt(tsvLines[0], 10))) {\n      bedStartIndex = 1;\n    }\n\n    rawAnnots = this.parseRawAnnots(annots, bedStartIndex, tsvLines, chrs);\n    return rawAnnots;\n  }\n\n}\n","/**\n * @fileoverview Functions used by parallel and collinear heatmaps.\n */\n\nvar reservedTrackKeys = [\n  'name', 'start', 'length', 'trackIndex', 'trackIndexOriginal', 'color'\n];\n\nvar defaultHeatmapColors = {\n  3: ['00B', 'DDD', 'F00'],\n  5: ['00D', '66D', 'DDD', 'F88', 'F00'],\n  17: [\n    '00D', '00D', '00D', '00D', '00D', '44D', '44D', 'DDD', 'DDD',\n    'DDD', 'DDD', 'F88', 'F66', 'F22', 'F22', 'F00', 'F00', 'F00'\n  ]\n};\n\n/**\n * Get label text for displayed tracks from annotation container metadata,\n * heatmap keys, or annotation container keys\n */\nfunction getLabels(ideo) {\n  var annotKeys, labels, heatmaps, i;\n\n  if (ideo.rawAnnots.metadata && ideo.rawAnnots.metadata.trackLabels) {\n    labels = ideo.rawAnnots.metadata.trackLabels;\n  } else if (ideo.config.heatmaps) {\n    labels = [];\n    heatmaps = ideo.config.heatmaps;\n    for (i = 0; i < heatmaps.length; i++) {\n      labels.push(heatmaps[i].key);\n    }\n  } else {\n    annotKeys = ideo.rawAnnots.keys.slice(0);\n    labels = annotKeys.filter(d => !reservedTrackKeys.includes(d));\n  }\n\n  if (ideo.displayedTrackIndexes) {\n    labels = labels.filter(function(d, i) {\n      return ideo.displayedTrackIndexes.includes(i + 1);\n    });\n  }\n\n  return labels;\n}\n\n/**\n * Apply heatmap thresholds that are passed in as annotation metadata\n */\nfunction inflateThresholds(ideo) {\n  var thresholds, colors,\n    rawAnnots = ideo.rawAnnots;\n\n  if (\n    rawAnnots.metadata && !rawAnnots.metadata.heatmapThresholds &&\n    !ideo.config.heatmapThresholds\n  ) {\n    return;\n  }\n\n  if (ideo.config.heatmapThresholds) {\n    thresholds = ideo.config.heatmapThresholds;\n  } else {\n    thresholds = ideo.rawAnnots.metadata.heatmapThresholds;\n  }\n\n  colors = defaultHeatmapColors[thresholds.length + 1];\n  thresholds = thresholds.map((d, i) => {\n    return [d, '#' + colors[i]];\n  });\n\n  thresholds.push(['+', '#' + colors.slice(-1)[0]]);\n\n  return thresholds;\n}\n\n/**\n * Set needed configuration options from raw annotation data.\n * Simplifies heatmap API by inferring reasonable defaults.\n */\nfunction inflateHeatmaps(ideo) {\n  var i, labels, heatmaps, annotationTracks, rawAnnots, displayedTracks,\n    thresholds = ideo.config.heatmapThresholds;\n\n  heatmaps = [];\n  rawAnnots = ideo.rawAnnots;\n  labels = rawAnnots.keys.slice(3);\n\n  annotationTracks = [];\n  displayedTracks = [];\n  if (rawAnnots.metadata || !isNaN(thresholds[0])) {\n    thresholds = inflateThresholds(ideo);\n  }\n\n  for (i = 0; i < labels.length; i++) {\n    heatmaps.push({key: labels[i], thresholds: thresholds});\n    annotationTracks.push({id: labels[i]});\n    displayedTracks.push(i + 1);\n  }\n  ideo.config.annotationsNumTracks = labels.length;\n  ideo.config.annotationsDisplayedTracks = displayedTracks;\n  ideo.config.heatmaps = heatmaps;\n  ideo.config.annotationTracks = annotationTracks;\n}\n\n/**\n * Given annotation value (m), should it use the color in this threshold?\n */\nfunction shouldUseThresholdColor(m, numThresholds, value, prevThreshold,\n  threshold) {\n\n  return (\n    // If this is the last threshold, and\n    // its value is \"+\" and the value is above the previous threshold...\n    m === numThresholds && (\n      threshold === '+' && value > prevThreshold\n    ) ||\n\n    // ... or if the value matches the threshold...\n    value === threshold ||\n\n    // ... or if this isn't the first or last threshold, and\n    // the value is between this threshold and the previous one...\n    m !== 0 && m !== numThresholds && (\n      value <= threshold &&\n      value > prevThreshold\n    ) ||\n\n    // ... or if this is the first threshold and the value is\n    // at or below the threshold\n    m === 0 && value <= threshold\n  );\n}\n\n/**\n * Determine the color of the heatmap annotation.\n */\nfunction getHeatmapAnnotColor(thresholds, value) {\n  var m, numThresholds, thresholdList, threshold, tvNum, thresholdColor,\n    prevThreshold, useThresholdColor, color;\n\n  for (m = 0; m < thresholds.length; m++) {\n    numThresholds = thresholds.length - 1;\n    thresholdList = thresholds[m];\n    threshold = thresholdList[0];\n\n    // The threshold value is usually a number,\n    // but can also be a \"+\" character indicating that\n    // this threshold is anything greater than the previous threshold.\n    tvNum = parseFloat(threshold);\n    if (isNaN(tvNum) === false) threshold = tvNum;\n    if (m !== 0) prevThreshold = parseFloat(thresholds[m - 1][0]);\n    thresholdColor = thresholdList[1];\n\n    useThresholdColor = shouldUseThresholdColor(m, numThresholds, value,\n      prevThreshold, threshold);\n\n    if (useThresholdColor) color = thresholdColor;\n  }\n\n  return color;\n}\n\nexport {\n  getLabels, inflateHeatmaps, inflateThresholds, defaultHeatmapColors,\n  getHeatmapAnnotColor\n};\n","/**\n * @fileoverview Functions for labeling collinear tracks of genome annotations.\n * See track-labels.js for more.\n */\n\nimport {d3} from '../lib';\nimport {getLabels} from './heatmap-lib';\n\nfunction renderTrackLabels(labels, ideo) {\n  var i, x, y, labelContainer, markBump,\n    annotLabelHeight = ideo.config.annotLabelHeight,\n    demarcateChrs = ideo.config.demarcateCollinearChromosomes;\n\n  x = 11; // Close to chrLeft in heatmap-collinear.js.  For tabs.\n  markBump = (demarcateChrs ? 2 : 0); // Make labels flush with demarcations\n\n  labelContainer =\n    d3.select(ideo.config.container + ' #_ideogramTrackLabelContainer');\n  labelContainer.html('');\n\n  y = ideo.config.annotationHeight + annotLabelHeight + 4;\n\n  for (i = 0; i < labels.length; i++) {\n    labelContainer\n      .style('position', 'absolute')\n      .append('div')\n      .attr('class', '_ideogramTrackLabel')\n      .style('opacity', 1)\n      .style('position', 'absolute')\n      .style('text-align', 'center')\n      .style('padding', '1px')\n      .style('font', '11px sans-serif')\n      .style('background', 'white')\n      .style('line-height', '10px')\n      .style('z-index', '5')\n      .style('left', (x + markBump) + 'px')\n      .style('top', (y * i + markBump) + 'px')\n      .style('width', 'max-content')\n      .style('transform-origin', 'bottom left')\n      .style('text-align', 'left')\n      .html(labels[i]);\n  }\n\n}\n\n/**\n * Show the label for this track\n */\nfunction writeTrackLabels(ideo) {\n  var labels = getLabels(ideo);\n  renderTrackLabels(labels, ideo);\n}\n\nexport {writeTrackLabels};\n","/**\n * @fileoverview Functions for collinear heatmaps of genome annotations.\n * See heatmap.js for more.\n */\n\nimport {d3} from '../lib';\nimport {writeTrackLabels} from './track-labels-collinear';\nimport {inflateHeatmaps} from './heatmap-lib';\n\n/**\n * Add canvases that will contain annotations.  One canvas per track.\n */\nfunction writeCanvases(chr, chrLeft, ideo) {\n  var j, trackLeft, trackWidth, canvas, context, id,\n    chrWidth = chr.width,\n    contextArray = [],\n    annotLabelHeight = ideo.config.annotLabelHeight,\n    numAnnotTracks = ideo.config.numAnnotTracks;\n\n  // Create a canvas for each annotation track on this chromosome\n  for (j = 0; j < numAnnotTracks; j++) {\n    trackWidth = ideo.config.annotationHeight + annotLabelHeight + 4;\n    id = chr.id + '-canvas-' + j; // e.g. chr1-9606-canvas-0\n    trackLeft = chrLeft;\n    if (chr.chrIndex > 0) {\n      trackLeft += (ideo.config.chrMargin * chr.chrIndex) - 1;\n    }\n    canvas = d3.select(ideo.config.container + ' #_ideogramInnerWrap')\n      .append('canvas')\n      .attr('id', id)\n      .attr('width', chrWidth + 1)\n      .attr('height', trackWidth)\n      .style('position', 'absolute')\n      .style('left', trackLeft + 'px')\n      .style('top', (trackWidth * j + 1) + 'px');\n    context = canvas.nodes()[0].getContext('2d');\n    contextArray.push([context, chr]);\n  }\n\n  return contextArray;\n}\n\n/**\n * Render annotations on the canvas\n */\nfunction fillCanvasAnnots(annots, contextArray, ideo) {\n  var j, annot, context, chr,\n    annotLabelHeight = ideo.config.annotLabelHeight,\n    annotHeight = ideo.config.annotationHeight,\n    demarcateChrs = ideo.config.demarcateCollinearChromosomes;\n\n  var trackWidth = annotHeight + annotLabelHeight + 4;\n\n  // Fill in the canvas(es) with annotation colors to draw a heatmap\n  for (j = 0; j < annots.length; j++) {\n    annot = annots[j];\n    context = contextArray[annot.trackIndex][0];\n    chr = contextArray[annot.trackIndex][1];\n    context.fillStyle = annot.color;\n    if (demarcateChrs) {\n      if (annot.startPx < 1 || annot.startPx > chr.width - 1) continue;\n      context.fillRect(annot.startPx, 1, 0.5, trackWidth);\n    } else {\n      context.fillRect(annot.startPx, annotLabelHeight + 1, 0.5, annotHeight);\n    }\n  }\n\n  if (demarcateChrs) {\n    for (j = 0; j < contextArray.length; j++) {\n      context = contextArray[j][0];\n      chr = contextArray[j][1];\n      context.fillStyle = '#555';\n      if (chr.chrIndex === 0) context.fillRect(0, 0, 1, trackWidth);\n      context.fillRect(chr.width - 1, 0, 1.1, trackWidth);\n      context.fillRect(0, 0, chr.width + 1, 1);\n      if (ideo.config.chrMargin) context.fillRect(0, 0, 1.1, trackWidth);\n    }\n  }\n}\n\n/**\n * Draw a 1D heatmap of annotations along each chromosome.\n * Ideal for representing very dense annotation sets in a granular manner\n * without subsampling.\n *\n * TODO:\n * - Support in 'vertical' orientation\n * - Support after rotating chromosome on click\n */\nfunction drawHeatmapsCollinear(annotContainers, ideo) {\n  var annots, chrLeft, contextArray, i, chr,\n    prevX = 0,\n    xBump = (ideo.config.showChromosomesLabels) ? 2 : -0.1;\n\n  d3.select(ideo.selector).classed('labeledLeft', false);\n  d3.selectAll(ideo.config.container + ' canvas').remove();\n\n  // Each \"annotationContainer\" represents annotations for a chromosome\n  for (i = 0; i < annotContainers.length; i++) {\n    annots = annotContainers[i].annots;\n    chr = ideo.chromosomesArray[i];\n    if (i === 0) {\n      chrLeft = 12;\n    } else {\n      chrLeft = prevX + ideo.chromosomesArray[i - 1].width + 14;\n      prevX += ideo.chromosomesArray[i - 1].width + xBump;\n    }\n    contextArray = writeCanvases(chr, chrLeft, ideo);\n    fillCanvasAnnots(annots, contextArray, ideo);\n  }\n\n  writeTrackLabels(ideo);\n\n  if (ideo.onDrawAnnotsCallback) ideo.onDrawAnnotsCallback();\n}\n\nexport {drawHeatmapsCollinear, inflateHeatmaps};\n","/**\n * @fileoverview Functions for 2D heatmaps of genome annotations.\n * 2D heatmaps enable showing many (100+) tracks of data in one dimension,\n * for features (e.g. genes) along a dimension of genomic coordinates in\n * chromosome context.\n *\n * TO DO:\n * - Horizontal orientation\n * - Multiple chromosomes\n * - Non-human organisms\n */\n\nimport {d3} from '../lib';\nimport {getHeatmapAnnotColor} from './heatmap-lib';\n\n/**\n * Add one canvas that will contain all annotations.  One canvas per chromosome.\n */\nfunction writeCanvas(chr, ideoHeight, width, ideo) {\n  var left, canvas, context, id;\n\n  id = chr.id + '-canvas'; // e.g. chr1-9606-canvas\n  left = (ideo.config.chrWidth * 2) + ideo.config.annotationHeight - 0.5;\n  canvas = d3.select(ideo.config.container + ' #_ideogramInnerWrap')\n    .append('canvas')\n    .attr('id', id)\n    .attr('width', width)\n    .attr('height', ideoHeight)\n    .style('position', 'absolute')\n    .style('left', left + 'px')\n    .style('top', '0px');\n  context = canvas.nodes()[0].getContext('2d');\n\n  return context;\n}\n\n/**\n * Render annotations on the canvas.\n *\n * These annotations are 2D; each annotation has many values, each on a track.\n */\nfunction fillCanvasAnnotValues(annot, context, ideo) {\n  var i, x, values,\n    annotHeight = ideo.config.annotationHeight,\n    ideoMarginTop = ideo._layout.margin.top;\n\n  values = annot.values;\n\n  // Fill canvas with annotation colors to draw the heatmap\n  for (i = 0; i < values.length; i++) {\n    context.fillStyle = values[i];\n    x = (i - 1) * annotHeight;\n    context.fillRect(x, annot.startPx + ideoMarginTop, annotHeight, 2);\n  }\n}\n\n/**\n * Draw a 2D heatmap of annotations along one chromosome.\n *\n * TODO:\n * - Support in 'horizontal' orientation\n * - Support after rotating chromosome on click\n */\nfunction drawHeatmaps2d(annotContainers, ideo) {\n  var annot, context, i, chr,\n    container = ideo.config.container,\n    ideoMarginTop = ideo._layout.margin.top,\n    ideoHeight = ideo.config.chrHeight + ideoMarginTop,\n    width = ideo.config.annotationHeight * annotContainers[0].values.length;\n\n  d3.selectAll(container + ' canvas').remove();\n\n  d3.select(container + ' #_ideogramInnerWrap')\n    .style('max-width', width + 'px');\n  d3.select(container + ' #_ideogram').attr('width', width);\n\n  chr = ideo.chromosomesArray[0];\n\n  context = writeCanvas(chr, ideoHeight, width, ideo);\n\n  // Each \"annotationContainer\" represents annotations for a chromosome\n  for (i = 0; i < annotContainers.length; i++) {\n    annot = annotContainers[i];\n    fillCanvasAnnotValues(annot, context, ideo);\n  }\n\n  if (ideo.onDrawAnnotsCallback) {\n    ideo.onDrawAnnotsCallback();\n  }\n}\n\nfunction add2dAnnotsForChr(annots, omittedAnnots, annotsByChr, chrModel,\n  m, keys, ideo) {\n  var j, k, annot, ra, stop, stopPx, color,\n    thresholds = ideo.config.heatmapThresholds;\n\n  for (j = 0; j < annotsByChr.annots.length; j++) {\n    ra = annotsByChr.annots[j];\n    annot = {};\n\n    annot.values = []; // one value per track\n\n    for (k = 0; k < 3; k++) {\n      annot[keys[k]] = ra[k];\n    }\n\n    for (k = 3; k < keys.length; k++) {\n      color = getHeatmapAnnotColor(thresholds, ra[k]);\n      annot.values.push(color);\n    }\n\n    stop = annot.start + annot.length;\n\n    annot.chr = annotsByChr.chr;\n    annot.chrIndex = m;\n    annot.startPx = ideo.convertBpToPx(chrModel, annot.start);\n    stopPx = ideo.convertBpToPx(chrModel, stop);\n    annot.px = Math.round((annot.startPx + stopPx) / 2);\n\n    annots.push(annot);\n  }\n\n  annots.shift();\n\n  return [annots, omittedAnnots];\n}\n\nexport {drawHeatmaps2d, add2dAnnotsForChr};\n","/**\n * @fileoverview Functions for labeling tracks of genome annotations.\n * Tracks are columns of annotations that run beside a chromosome.\n * Labeling tracks with descriptive names makes them easier to understand.\n */\n\nimport {d3} from '../lib';\nimport {getLabels} from './heatmap-lib';\n\n/**\n * Start a timer that, upon expiring, hides the track label.\n *\n * To enable users to copy label content to their clipboard, a timer is\n * used to control when the label disappears.  It starts when the user's\n * cursor leaves the track or the label.  If the user moves the cursor\n * back over the annot or label after the timer starts and before it expires,\n * then the timer is cleared.\n */\nfunction startHideTrackLabelTimeout(ideo) {\n  if (ideo.config.showTrackLabel === false) return;\n\n  ideo.hideTrackLabelTimeout = window.setTimeout(function() {\n    d3.select(ideo.config.container + ' #_ideogramTrackLabel').transition()\n      .duration(500)\n      .style('opacity', 0);\n  }, 250);\n}\n\n/**\n * Write label div setup with default styling.\n */\nfunction writeTrackLabelContainer(ideo) {\n  d3.select(ideo.config.container + ' #_ideogramTrackLabelContainer')\n    .append('div')\n    .attr('id', '_ideogramTrackLabel')\n    .style('opacity', 0)\n    .style('position', 'absolute')\n    .style('text-align', 'center')\n    .style('padding', '1px')\n    .style('font', '11px sans-serif')\n    .style('background', 'white')\n    .style('line-height', '10px')\n    .style('z-index', '9000');\n}\n\n/**\n * Display track labels on the page\n */\nfunction renderTrackLabels(top, left, ideo) {\n  d3.select(ideo.config.container + ' #_ideogramTrackLabel')\n    .style('opacity', 1) // Make label visible\n    .style('left', left + 'px')\n    .style('top', top + 'px')\n    .style('width', 'max-content')\n    .style('transform-origin', 'bottom left')\n    .style('text-align', 'left')\n    .on('mouseover', function() {\n      clearTimeout(ideo.hideTrackLabelTimeout);\n    })\n    .on('mouseout', function() {\n      startHideTrackLabelTimeout(ideo);\n    });\n}\n\n/**\n * Get left and top (x and y) offset for track label text\n */\nfunction getTrackLabelOffsets(labels, trackCanvas, ideo) {\n  var firstTrackId, firstTrack, trackBox, labelBox, ideoBox, left, top,\n    marginHack = 7; // TODO: Make this dynamic\n\n  firstTrackId = trackCanvas.id.split('-').slice(0, -1).join('-') + '-0';\n  firstTrack = d3.select(ideo.config.container + ' #' + firstTrackId)\n    .nodes()[0];\n  trackBox = firstTrack.getBoundingClientRect();\n\n  labelBox = d3.select(ideo.config.container + ' #_ideogramTrackLabel')\n    .nodes()[0].getBoundingClientRect();\n  ideoBox = d3.select(ideo.config.container).nodes()[0]\n    .getBoundingClientRect();\n\n  left = Math.round(trackBox.left + labelBox.width) - trackBox.width - 1;\n  left -= ideoBox.left - marginHack;\n  top = -(labels.split('<br>').length - 2) * trackBox.width + 2;\n\n  return [left, top];\n}\n\n/**\n * Show the label for this track\n */\nfunction showTrackLabel(trackCanvas, ideo) {\n  var labels, left, top;\n\n  clearTimeout(ideo.hideTrackLabelTimeout);\n\n  labels = getLabels(ideo);\n  labels = labels.join('<br>');\n\n  // Clear any previous positioning, write track label text to DOM\n  d3.select(ideo.config.container + ' #_ideogramTrackLabel')\n    .interrupt() // Stop any in-progress disapperance\n    .style('top', '')\n    .style('left', '')\n    .style('transform', null)\n    .style('transform', 'rotate(-90deg)')\n    .html(labels);\n\n  [left, top] = getTrackLabelOffsets(labels, trackCanvas, ideo);\n\n  renderTrackLabels(top, left, ideo);\n}\n\nexport {\n  startHideTrackLabelTimeout, writeTrackLabelContainer, showTrackLabel\n};\n","/**\n * @fileoverview Functions for 2D heatmaps of genome annotations.\n * Heatmaps provide an easy way to visualize very dense annotation data.\n * Unlike the rest of Ideogram's graphics, which use SVG, heatmaps are\n * rendered using the Canvas element.\n */\n\nimport {d3} from '../lib';\nimport {drawHeatmapsCollinear} from './heatmap-collinear';\nimport {drawHeatmaps2d} from './heatmap-2d';\nimport {getHeatmapAnnotColor} from './heatmap-lib';\n\nimport {\n  startHideTrackLabelTimeout, writeTrackLabelContainer, showTrackLabel\n} from './track-labels';\n\n/**\n * Add canvases that will contain annotations.  One canvas per track.\n */\nfunction writeCanvases(chr, chrLeft, ideoHeight, ideo) {\n  var j, trackLeft, trackWidth, canvas, context, id,\n    contextArray = [],\n    numAnnotTracks = ideo.config.numAnnotTracks;\n\n  var marginHack = 7; // TODO: Make this dynamic\n\n  // Create a canvas for each annotation track on this chromosome\n  for (j = 0; j < numAnnotTracks; j++) {\n    trackWidth = ideo.config.annotationHeight;\n    id = chr.id + '-canvas-' + j; // e.g. chr1-9606-canvas-0\n    trackLeft = chrLeft - trackWidth * (numAnnotTracks - j) - marginHack;\n    canvas = d3.select(ideo.config.container + ' #_ideogramInnerWrap')\n      .append('canvas')\n      .attr('id', id)\n      .attr('width', trackWidth)\n      .attr('height', ideoHeight)\n      .style('position', 'absolute')\n      .style('left', trackLeft + 'px');\n    context = canvas.nodes()[0].getContext('2d');\n    contextArray.push(context);\n  }\n\n  return contextArray;\n}\n\n/**\n * Render annotations on the canvas\n */\nfunction fillCanvasAnnots(annots, contextArray, chrWidth, ideoMarginTop) {\n  var j, annot, context, x;\n\n  // Fill in the canvas(es) with annotation colors to draw a heatmap\n  for (j = 0; j < annots.length; j++) {\n    annot = annots[j];\n    context = contextArray[annot.trackIndex];\n    context.fillStyle = annot.color;\n    x = annot.trackIndex - 1;\n    context.fillRect(x, annot.startPx + ideoMarginTop, chrWidth, 0.5);\n  }\n}\n\n/**\n * Draw a 1D heatmap of annotations along each chromosome.\n * Ideal for representing very dense annotation sets in a granular manner\n * without subsampling.\n *\n * TODO:\n * - Support in 'horizontal' orientation\n * - Support after rotating chromosome on click\n */\nfunction drawHeatmaps(annotContainers) {\n  var annots, chrLeft, contextArray, chrWidth, i, chr,\n    ideo = this,\n    config = ideo.config,\n    ideoMarginTop = ideo._layout.margin.top,\n    ideoHeight = config.chrHeight + ideoMarginTop;\n\n  if (config.geometry === 'collinear') {\n    return drawHeatmapsCollinear(annotContainers, ideo);\n  } else if (config.annotationsLayout === 'heatmap-2d') {\n    return drawHeatmaps2d(annotContainers, ideo);\n  }\n\n  d3.selectAll(ideo.config.container + ' canvas').remove();\n\n  writeTrackLabelContainer(ideo);\n\n  // Each \"annotationContainer\" represents annotations for a chromosome\n  for (i = 0; i < annotContainers.length; i++) {\n\n    annots = annotContainers[i].annots;\n    chr = ideo.chromosomesArray[i];\n    chrWidth = ideo.config.chrWidth;\n    chrLeft = ideo._layout.getChromosomeSetYTranslate(i);\n\n    contextArray = writeCanvases(chr, chrLeft, ideoHeight, ideo);\n    fillCanvasAnnots(annots, contextArray, chrWidth, ideoMarginTop);\n  }\n\n  d3.selectAll(ideo.config.container + ' canvas')\n    .on('mouseover', function() {showTrackLabel(this, ideo);})\n    .on('mouseout', function() {startHideTrackLabelTimeout(ideo);});\n\n  if (ideo.onDrawAnnotsCallback) {\n    ideo.onDrawAnnotsCallback();\n  }\n}\n\n/**\n * Set color and track index for raw annotation objects.\n */\nfunction getNewRawAnnots(heatmapKeyIndexes, rawAnnots, ideo) {\n  var j, k, ra, newRa, value, thresholds, color, trackIndex,\n    newRas = [];\n\n  for (j = 0; j < rawAnnots.length; j++) {\n    ra = rawAnnots[j];\n    for (k = 0; k < heatmapKeyIndexes.length; k++) {\n      newRa = ra.slice(0, 3); // name, start, length\n\n      value = ra[heatmapKeyIndexes[k]];\n      thresholds = ideo.config.heatmaps[k].thresholds;\n      color = getHeatmapAnnotColor(thresholds, value);\n\n      trackIndex = k;\n      newRa.push(trackIndex, color, value);\n      newRas.push(newRa);\n    }\n  }\n\n  return newRas;\n}\n\nfunction getNewRawAnnotContainers(heatmapKeyIndexes, rawAnnotBoxes, ideo) {\n  var raContainer, chr, rawAnnots, newRas, i,\n    newRaContainers = [];\n\n  for (i = 0; i < rawAnnotBoxes.length; i++) {\n    raContainer = rawAnnotBoxes[i];\n    chr = raContainer.chr;\n\n    rawAnnots = raContainer.annots;\n    newRas = getNewRawAnnots(heatmapKeyIndexes, rawAnnots, ideo);\n\n    newRaContainers.push({chr: chr, annots: newRas});\n  }\n  return newRaContainers;\n}\n\nfunction reportPerformance(t0, ideo) {\n  var t1 = new Date().getTime();\n  if (ideo.config.debug) {\n    console.log('Time in deserializeAnnotsForHeatmap: ' + (t1 - t0) + ' ms');\n  }\n}\n\n/**\n * Deserialize compressed annotation data into a format suited for heatmaps.\n *\n * This enables the annotations to be downloaded from a server without the\n * requested annotations JSON needing to explicitly specify track index or\n * color.  The track index and color are inferred from the \"heatmaps\" Ideogram\n * configuration option defined before ideogram initialization.\n *\n * This saves time for the user.\n *\n * @param rawAnnotsContainer {Object} Raw annotations as passed from server\n */\nfunction deserializeAnnotsForHeatmap(rawAnnotsContainer) {\n  var newRaContainers, heatmapKey, heatmapKeyIndexes, i,\n    t0 = new Date().getTime(),\n    keys = rawAnnotsContainer.keys,\n    rawAnnotBoxes = rawAnnotsContainer.annots,\n    ideo = this;\n\n  heatmapKeyIndexes = [];\n  for (i = 0; i < ideo.config.heatmaps.length; i++) {\n    heatmapKey = ideo.config.heatmaps[i].key;\n    heatmapKeyIndexes.push(keys.indexOf(heatmapKey));\n  }\n\n  newRaContainers =\n    getNewRawAnnotContainers(heatmapKeyIndexes, rawAnnotBoxes, ideo);\n\n  keys.splice(3, 0, 'trackIndex');\n  keys.splice(4, 0, 'color');\n\n  ideo.rawAnnots.keys = keys;\n  ideo.rawAnnots.annots = newRaContainers;\n\n  reportPerformance(t0, ideo);\n}\n\nexport {drawHeatmaps, deserializeAnnotsForHeatmap};\n","import {d3} from '../lib';\n\n/**\n * Optional callback, invoked when annotations are drawn\n */\nfunction onLoadAnnots() {\n  call(this.onLoadAnnotsCallback);\n}\n\n/**\n * Optional callback, invoked when annotations are drawn\n */\nfunction onDrawAnnots() {\n  call(this.onDrawAnnotsCallback);\n}\n\n/**\n * Starts a timer that, upon expiring, hides the annotation tooltip.\n *\n * To enable users to copy tooltip content to their clipboard, a timer is\n * used to control when the tooltip disappears.  It starts when the user's\n * cursor leaves the annotation or the tooltip.  If the user moves the cursor\n * back over the annot or tooltip after the timer starts and before it expires,\n * then the timer is cleared.\n */\nfunction startHideAnnotTooltipTimeout() {\n\n  if (this.config.showAnnotTooltip === false) {\n    return;\n  }\n\n  this.hideAnnotTooltipTimeout = window.setTimeout(function() {\n    d3.select('._ideogramTooltip').transition()\n      .duration(500)\n      .style('opacity', 0)\n      .style('pointer-events', 'none');\n  }, 250);\n}\n\nfunction writeTooltip(tooltip, content, matrix, yOffset, ideo) {\n  tooltip.html(content)\n    .style('opacity', 1) // Make tooltip visible\n    .style('left', matrix.e + 'px')\n    .style('top', (matrix.f - yOffset) + 'px')\n    .style('pointer-events', null) // Prevent bug in clicking chromosome\n    .on('mouseover', function() {\n      clearTimeout(ideo.hideAnnotTooltipTimeout);\n    })\n    .on('mouseout', function() {\n      ideo.startHideAnnotTooltipTimeout();\n    });\n}\n\nfunction getContentAndYOffset(annot) {\n  var content, yOffset, range, displayName;\n\n  range = 'chr' + annot.chr + ':' + annot.start.toLocaleString();\n  if (annot.length > 0) {\n    // Only show range if stop differs from start\n    range += '-' + annot.stop.toLocaleString();\n  }\n  content = range;\n  yOffset = 24;\n\n  if (annot.name) {\n    displayName = annot.displayName ? annot.displayName : annot.name;\n    content = displayName + '<br/>' + content;\n    yOffset += 8;\n  }\n\n  return [content, yOffset];\n}\n\n/**\n * Optional callback, invoked before showing annotation tooltip\n */\nfunction onWillShowAnnotTooltip(annot) {\n  call(this.onWillShowAnnotTooltipCallback, annot);\n}\n\n/**\n * Optional callback, invoked on clicking annotation\n */\nfunction onClickAnnot(annot) {\n  this.onClickAnnotCallback(annot);\n}\n\n/**\n * Shows a tooltip for the given annotation.\n *\n * See notes in startHideAnnotTooltipTimeout about show/hide logic.\n *\n * @param annot {Object} Processed annotation object\n * @param context {Object} \"This\" of the caller -- an SVG path DOM object\n */\nfunction showAnnotTooltip(annot, context) {\n  var matrix, content, yOffset, tooltip,\n    cx = Number(context.getAttribute('cx')),\n    cy = Number(context.getAttribute('cy')),\n    ideo = this;\n\n  if (ideo.config.showAnnotTooltip === false) return;\n\n  clearTimeout(ideo.hideAnnotTooltipTimeout);\n\n  if (ideo.onWillShowAnnotTooltipCallback) {\n    annot = ideo.onWillShowAnnotTooltipCallback(annot);\n  }\n\n  tooltip = d3.select('._ideogramTooltip');\n  tooltip.interrupt(); // Stop any in-progress disapperance\n\n  matrix = context.getScreenCTM().translate(cx, cy);\n\n  [content, yOffset] = getContentAndYOffset(annot);\n\n  writeTooltip(tooltip, content, matrix, yOffset, ideo);\n}\n\nexport {\n  onLoadAnnots, onDrawAnnots, startHideAnnotTooltipTimeout,\n  onWillShowAnnotTooltip, showAnnotTooltip, onClickAnnot\n};\n","/**\n * Get containers to group individual annotations into higher-level \"bar\"\n * annotations.\n */\nfunction getRawBars(chrModels, ideo) {\n  var chr, chrModel, lastBand, numBins, bar, i, px,\n    barWidth = ideo.config.barWidth,\n    bars = [];\n\n  for (chr in chrModels) {\n    chrModel = chrModels[chr];\n    lastBand = chrModel.bands[chrModel.bands.length - 1];\n    numBins = Math.round(lastBand.px.stop / barWidth); // chrPxStop / barWidth\n    bar = {chr: chr, annots: []};\n    for (i = 0; i < numBins; i++) {\n      px = i * barWidth - ideo.bump;\n      bar.annots.push({\n        bp: ideo.convertPxToBp(chrModel, px + ideo.bump),\n        px: px,\n        count: 0,\n        chrIndex: chrModel.chrIndex,\n        chrName: chr,\n        color: ideo.config.annotationsColor,\n        annots: []\n      });\n    }\n    bars.push(bar);\n  }\n  return bars;\n}\n\n/**\n * Assign how many, and which annotations each histogram bar contains\n */\nfunction assignAnnotsToBars(annots, bars, chrModels, ideo) {\n  var chr, chrAnnots, chrModel, barAnnots, i, annot, px, j, barPx, nextBarPx,\n    barWidth = ideo.config.barWidth;\n\n  for (chr in annots) {\n    chrAnnots = annots[chr].annots;\n    chrModel = chrModels[annots[chr].chr]; // get chr by name\n    barAnnots = bars[chrModel.chrIndex].annots;\n    for (i = 0; i < chrAnnots.length; i++) {\n      annot = chrAnnots[i];\n      px = annot.px - ideo.bump;\n      for (j = 0; j < barAnnots.length; j++) {\n        barPx = barAnnots[j].px;\n        nextBarPx = barPx + barWidth;\n        if (j === barAnnots.length - 1) nextBarPx += barWidth;\n        if (px >= barPx && px < nextBarPx) {\n          bars[chrModel.chrIndex].annots[j].count += 1;\n          bars[chrModel.chrIndex].annots[j].annots.push(annot);\n          break;\n        }\n      }\n    }\n  }\n  return bars;\n}\n\nfunction setIdeoMaxAnnotsPerBar(bars, isFirstGet, ideo) {\n  var maxAnnotsPerBarAllChrs, i, maxAnnotsPerBar, annots, chr, j, barCount;\n\n  if (isFirstGet || ideo.config.histogramScaling === 'relative') {\n    maxAnnotsPerBarAllChrs = 0;\n    for (i = 0; i < bars.length; i++) {\n      maxAnnotsPerBar = 0;\n      annots = bars[i].annots;\n      chr = bars[i].chr;\n      for (j = 0; j < annots.length; j++) {\n        barCount = annots[j].count;\n        if (barCount > maxAnnotsPerBar) maxAnnotsPerBar = barCount;\n        if (barCount > maxAnnotsPerBarAllChrs) {\n          maxAnnotsPerBarAllChrs = barCount;\n        }\n      }\n      ideo.maxAnnotsPerBar[chr] = maxAnnotsPerBar;\n    }\n    ideo.maxAnnotsPerBarAllChrs = maxAnnotsPerBarAllChrs;\n  }\n}\n\n/**\n * Set each bar's height to be proportional to the height of the bar with the\n * most annotations\n */\nfunction setProportionalBarHeight(bars, ideo) {\n  var i, annots, chr, j, barCount, barCountRatio, height,\n    ideoIsRotated = ideo._layout._isRotated;\n\n  for (i = 0; i < bars.length; i++) {\n    annots = bars[i].annots;\n    chr = bars[i].chr;\n    for (j = 0; j < annots.length; j++) {\n      barCount = annots[j].count;\n      if (ideo.config.histogramScaling === 'relative') {\n        barCountRatio = barCount / ideo.maxAnnotsPerBar[chr];\n      } else {\n        barCountRatio = barCount / ideo.maxAnnotsPerBarAllChrs;\n      }\n      if (ideoIsRotated === false) {\n        height = barCountRatio * ideo.config.chrMargin;\n      } else {\n        height = barCountRatio * ideo.config.chrHeightOriginal * 3;\n      }\n      if (isNaN(height)) {\n        height = 0;\n      }\n      bars[i].annots[j].height = height;\n    }\n  }\n  return bars;\n}\n\nfunction reportGetHistogramBarPerformance(t0, ideo) {\n  var t1 = new Date().getTime();\n  if (ideo.config.debug) {\n    console.log('Time spent in getHistogramBars: ' + (t1 - t0) + ' ms');\n  }\n}\n\nfunction setIdeoHistogramScaling(ideo) {\n  if ('histogramScaling' in ideo.config === false) {\n    ideo.config.histogramScaling = 'absolute';\n  }\n}\n\n/**\n * Returns and sets bars used for histogram\n */\nfunction getHistogramBars(annots) {\n  var chrModels, bars,\n    isFirstGet = false,\n    t0 = new Date().getTime(),\n    ideo = this;\n\n  chrModels = ideo.chromosomes[ideo.config.taxid];\n\n  setIdeoHistogramScaling(ideo);\n\n  if (typeof ideo.maxAnnotsPerBar === 'undefined') {\n    ideo.maxAnnotsPerBar = {};\n    isFirstGet = true;\n  }\n\n  bars = getRawBars(chrModels, ideo);\n  bars = assignAnnotsToBars(annots, bars, chrModels, ideo);\n  setIdeoMaxAnnotsPerBar(bars, isFirstGet, ideo);\n  bars = setProportionalBarHeight(bars, ideo);\n\n  reportGetHistogramBarPerformance(t0, ideo);\n  ideo.bars = bars;\n  return bars;\n}\n\nfunction getHistogramPoints(d, chrWidth, chrWidths, ideo) {\n  var x1, x2, y1, y2;\n\n  x1 = d.px + ideo.bump;\n  x2 = d.px + ideo.config.barWidth + ideo.bump;\n  y1 = chrWidth;\n  y2 = chrWidth + d.height;\n\n  var thisChrWidth = chrWidths[d.chr];\n\n  if (x2 > thisChrWidth) {\n    x2 = thisChrWidth;\n  }\n\n  return (\n    x1 + ',' + y1 + ' ' +\n    x2 + ',' + y1 + ' ' +\n    x2 + ',' + y2 + ' ' +\n    x1 + ',' + y2\n  );\n}\n\nfunction writeHistogramAnnots(chrAnnot, ideo) {\n  var chrs, chr,\n    chrWidths = {},\n    chrWidth = ideo.config.chrWidth;\n\n  chrs = ideo.chromosomes[ideo.config.taxid];\n  for (chr in chrs) {\n    chrWidths[chr] = chrs[chr];\n  }\n\n  chrAnnot.append('polygon')\n    // .attr('id', function(d, i) { return d.id; })\n    .attr('class', 'annot')\n    .attr('points', function(d) {\n      return getHistogramPoints(d, chrWidth, chrWidths, ideo);\n    })\n    .attr('fill', function(d) {return d.color;});\n}\n\nexport {getHistogramBars, writeHistogramAnnots};\n","/**\n * @fileoverview Functions for drawing a legend for genome annotations.\n * A legend consists of rows, each with a colored icon and a text label.\n * Icons may have different shapes.  A legend may also have a name.\n */\n\nimport {d3} from '../lib';\n\nvar lineHeight = 19;\n\nvar legendStyle =\n  '#_ideogramLegend {font: 12px Arial; line-height: 19px; overflow: auto;} ' +\n  '#_ideogramLegend svg {float: left;} ' +\n  '#_ideogramLegend ul {' +\n    'position: relative; left: -14px; list-style: none; float: left; ' +\n    'padding-left: 10px; margin: 0 0 1em 0; width: auto; border: none;' +\n  '} ' +\n  '#_ideogramLegend li {float: none; margin: 0;}' +\n  '#_ideogramLegend ul span {position: relative; left: -15px;} ';\n\nfunction getIcon(row) {\n  var icon, triangleAttrs, circleAttrs, rectAttrs,\n    fill = 'fill=\"' + row.color + '\" style=\"stroke: #AAA;\"',\n    shape = row.shape;\n\n  triangleAttrs = 'd=\"m7,3 l -5 9 l 9 0 z\"';\n  circleAttrs = 'd=\"m2,9a 4.5,4.5 0 1,0 9,0a 4.5,4.5 0 1,0 -9,0\"';\n  rectAttrs = 'height=\"10\" width=\"10\"  y=\"3\"';\n\n  if ('shape' in row && ['circle', 'triangle'].includes(shape)) {\n    if (shape === 'circle') {\n      icon = '<path ' + circleAttrs + ' ' + fill + '></path>';\n    } else if (shape === 'triangle') {\n      icon = '<path ' + triangleAttrs + ' ' + fill + '></path>';\n    }\n  } else {\n    icon = '<rect ' + rectAttrs + ' ' + fill + '/>';\n  }\n\n  return icon;\n}\n\nfunction getListItems(labels, svg, list) {\n  var i, icon, y, row;\n  for (i = 0; i < list.rows.length; i++) {\n    row = list.rows[i];\n    labels += '<li>' + row.name + '</li>';\n    y = lineHeight * i;\n    if ('name' in list) y += lineHeight;\n    icon = getIcon(row);\n    svg += '<g transform=\"translate(0, ' + y + ')\">' + icon + '</g>';\n  }\n\n  return [labels, svg];\n}\n\n/**\n * Display a legend for genome annotations, using `legend` configuration option\n */\nfunction writeLegend(ideo) {\n  var i, legend, svg, labels, list, content;\n\n  d3.select(ideo.config.container + ' #_ideogramLegend').remove();\n\n  legend = ideo.config.legend;\n  content = '';\n\n  for (i = 0; i < legend.length; i++) {\n    list = legend[i];\n    if ('name' in list) labels = '<span>' + list.name + '</span>';\n    svg = '<svg width=\"' + lineHeight + '\">';\n    [labels, svg] = getListItems(labels, svg, list);\n    svg += '</svg>';\n    content += svg + '<ul>' + labels + '</ul>';\n  }\n\n  var target = d3.select(ideo.config.container + ' #_ideogramOuterWrap');\n  target.append('style').html(legendStyle);\n  target.append('div').attr('id', '_ideogramLegend').html(content);\n}\n\nexport {writeLegend};\n","import {d3} from '../lib';\nimport {writeHistogramAnnots} from './histogram';\nimport {writeLegend} from './legend';\n\nfunction parseFriendlyAnnots(friendlyAnnots, rawAnnots) {\n  var i, j, annot, rawAnnot;\n\n  for (i = 0; i < friendlyAnnots.length; i++) {\n    annot = friendlyAnnots[i];\n\n    for (j = 0; j < rawAnnots.length; j++) {\n      if (annot.chr === rawAnnots[j].chr) {\n        rawAnnot = [\n          annot.name,\n          annot.start,\n          annot.stop - annot.start\n        ];\n        if ('color' in annot) rawAnnot.push(annot.color);\n        if ('shape' in annot) rawAnnot.push(annot.shape);\n        rawAnnots[j].annots.push(rawAnnot);\n        break;\n      }\n    }\n  }\n\n  return rawAnnots;\n}\n\nfunction parseFriendlyKeys(friendlyAnnots) {\n  var keys = ['name', 'start', 'length'];\n  if ('color' in friendlyAnnots[0]) {\n    keys.push('color');\n  }\n  if ('shape' in friendlyAnnots[0]) {\n    keys.push('shape');\n  }\n  return keys;\n}\n\n/**\n * Draws annotations defined by user\n */\nfunction drawAnnots(friendlyAnnots) {\n  var keys, chr,\n    rawAnnots = [],\n    ideo = this,\n    chrs = ideo.chromosomes[ideo.config.taxid]; // TODO: multiorganism\n\n  if (\n    'annots' in friendlyAnnots[0] || // When filtering\n    'values' in friendlyAnnots[0] // When drawing cached expression matrices\n  ) {\n    return ideo.drawProcessedAnnots(friendlyAnnots);\n  }\n\n  for (chr in chrs) {\n    rawAnnots.push({chr: chr, annots: []});\n  }\n  rawAnnots = parseFriendlyAnnots(friendlyAnnots, rawAnnots);\n\n  keys = parseFriendlyKeys(friendlyAnnots);\n\n  ideo.rawAnnots = {keys: keys, annots: rawAnnots};\n  ideo.annots = ideo.processAnnotData(ideo.rawAnnots);\n\n  ideo.drawProcessedAnnots(ideo.annots);\n}\n\nfunction getShapes(annotHeight) {\n  var triangle, circle, rectangle, r;\n\n  triangle =\n    'm0,0 l -' + annotHeight + ' ' + (2 * annotHeight) +\n    ' l ' + (2 * annotHeight) + ' 0 z';\n\n  // From http://stackoverflow.com/a/10477334, with a minor change (\"m -r, r\")\n  // Circles are supported natively via <circle>, but having it as a path\n  // simplifies handling triangles, circles and other shapes in the same\n  // D3 call\n  r = annotHeight;\n  circle =\n    'm -' + r + ', ' + r +\n    'a ' + r + ',' + r + ' 0 1,0 ' + (r * 2) + ',0' +\n    'a ' + r + ',' + r + ' 0 1,0 -' + (r * 2) + ',0';\n\n  rectangle =\n    'm0,0 l 0 ' + (2 * annotHeight) +\n    'l ' + annotHeight + ' 0' +\n    'l 0 -' + (2 * annotHeight) + 'z';\n\n  return {triangle: triangle, circle: circle, rectangle: rectangle};\n}\n\nfunction getChrAnnotNodes(filledAnnots, ideo) {\n  return d3.selectAll(ideo.selector + ' .chromosome')\n    .data(filledAnnots)\n    .selectAll('path.annot')\n    .data(function(d) {\n      return d.annots;\n    })\n    .enter();\n}\n\nfunction determineShape(d, shapes) {\n  if (!d.shape || d.shape === 'triangle') {\n    return shapes.triangle;\n  } else if (d.shape === 'circle') {\n    return shapes.circle;\n  } else if (d.shape === 'rectangle') {\n    return shapes.rectangle;\n  } else {\n    return d.shape;\n  }\n}\n\nfunction writeTrackAnnots(chrAnnot, ideo) {\n  var shapes,\n    annotHeight = ideo.config.annotationHeight;\n\n  shapes = getShapes(annotHeight);\n\n  chrAnnot.append('g')\n    .attr('id', function(d) {return d.id;})\n    .attr('class', 'annot')\n    .attr('transform', function(d) {\n      var y = ideo.config.chrWidth + (d.trackIndex * annotHeight * 2);\n      return 'translate(' + d.px + ',' + y + ')';\n    })\n    .append('path')\n    .attr('d', function(d) {return determineShape(d, shapes);})\n    .attr('fill', function(d) {return d.color;})\n    .on('mouseover', function(d) {ideo.showAnnotTooltip(d, this);})\n    .on('mouseout', function() {ideo.startHideAnnotTooltipTimeout();})\n    .on('click', function(d) {ideo.onClickAnnot(d);});\n}\n\n/**\n * Overlaid annotations appear directly on chromosomes\n */\nfunction writeOverlayAnnots(chrAnnot, ideo) {\n  chrAnnot.append('polygon')\n    .attr('id', function(d) {return d.id;})\n    .attr('class', 'annot')\n    .attr('points', function(d) {\n      var x1, x2,\n        chrWidth = ideo.config.chrWidth;\n\n      if (d.stopPx - d.startPx > 1) {\n        x1 = d.startPx;\n        x2 = d.stopPx;\n      } else {\n        x1 = d.px - 0.5;\n        x2 = d.px + 0.5;\n      }\n\n      return (\n        x1 + ',' + chrWidth + ' ' + x2 + ',' + chrWidth + ' ' +\n        x2 + ',0 ' + x1 + ',0'\n      );\n    })\n    .attr('fill', function(d) {return d.color;})\n    .on('mouseover', function(d) {ideo.showAnnotTooltip(d, this);})\n    .on('mouseout', function() {ideo.startHideAnnotTooltipTimeout();});\n}\n\nfunction warnIfTooManyAnnots(layout, annots) {\n  var i, numAnnots;\n\n  if (!/heatmap/.test(layout) && layout !== 'histogram') {\n    numAnnots = 0;\n    for (i = 0; i < annots.length; i++) {\n      numAnnots += annots[i].annots.length;\n    }\n    if (numAnnots > 2000) {\n      console.warn(\n        'Rendering more than 2000 annotations in Ideogram?\\n' +\n        'Try setting \"annotationsLayout\" to \"heatmap\" or \"histogram\" in your ' +\n        'Ideogram configuration object for better layout and performance.'\n      );\n    }\n  }\n}\n\nfunction drawAnnotsByLayoutType(layout, annots, ideo) {\n  var filledAnnots, chrAnnot;\n\n  warnIfTooManyAnnots(layout, annots);\n\n  if (layout === 'histogram') annots = ideo.getHistogramBars(annots);\n\n  filledAnnots = ideo.fillAnnots(annots);\n\n  chrAnnot = getChrAnnotNodes(filledAnnots, ideo);\n\n  if (layout === 'tracks') {\n    writeTrackAnnots(chrAnnot, ideo);\n  } else if (layout === 'overlay') {\n    writeOverlayAnnots(chrAnnot, ideo);\n  } else if (layout === 'histogram') {\n    writeHistogramAnnots(chrAnnot, ideo);\n  }\n}\n\n/**\n * Draws genome annotations on chromosomes.\n * Annotations can be rendered as either overlaid directly\n * on a chromosome, or along one or more \"tracks\"\n * running parallel to each chromosome.\n */\nfunction drawProcessedAnnots(annots) {\n  var layout,\n    ideo = this;\n\n  d3.selectAll(ideo.selector + ' .annot').remove();\n\n  layout = 'tracks';\n  if (ideo.config.annotationsLayout) layout = ideo.config.annotationsLayout;\n\n  if ('legend' in ideo.config) writeLegend(ideo);\n\n  if (/heatmap/.test(layout)) {\n    ideo.drawHeatmaps(annots);\n    return;\n  }\n\n  drawAnnotsByLayoutType(layout, annots, ideo);\n  if (ideo.onDrawAnnotsCallback) ideo.onDrawAnnotsCallback();\n}\n\nexport {drawAnnots, drawProcessedAnnots};\n","import {d3} from '../lib';\n\nexport function writeSyntenicRegion(syntenies, regionID, ideo) {\n  return syntenies.append('g')\n    .attr('class', 'syntenicRegion')\n    .attr('id', regionID)\n    .on('click', function() {\n      var activeRegion = this;\n      var others = d3.selectAll(ideo.selector + ' .syntenicRegion')\n        .filter(function() {return (this !== activeRegion);});\n\n      others.classed('hidden', !others.classed('hidden'));\n    })\n    .on('mouseover', function() {\n      var activeRegion = this;\n      d3.selectAll(ideo.selector + ' .syntenicRegion')\n        .filter(function() {return (this !== activeRegion);})\n        .classed('ghost', true);\n    })\n    .on('mouseout', function() {\n      d3.selectAll(ideo.selector + ' .syntenicRegion')\n        .classed('ghost', false);\n    });\n}\n\nexport function writeSyntenicRegionPolygons(\n  syntenicRegion, x1, x2, r1, r2, regions\n) {\n  var color, opacity;\n\n  color = ('color' in regions) ? regions.color : '#CFC';\n  opacity = ('opacity' in regions) ? regions.opacity : 1;\n\n  syntenicRegion.append('polygon')\n    .attr('points',\n      x1 + ', ' + r1.startPx + ' ' +\n      x1 + ', ' + r1.stopPx + ' ' +\n      x2 + ', ' + r2.stopPx + ' ' +\n      x2 + ', ' + r2.startPx\n    )\n    .style('fill', color)\n    .style('fill-opacity', opacity);\n}\n\nexport function writeSyntenicRegionPolygonsHorizontal(\n  syntenicRegion, y1, y2, r1, r2, regions\n) {\n  var color, opacity;\n\n  color = ('color' in regions) ? regions.color : '#CFC';\n  opacity = ('opacity' in regions) ? regions.opacity : 1;\n\n  syntenicRegion.append('polygon')\n    .attr('points',\n      (r1.startPx - 15) + ', ' + y1 + ' ' +\n      (r1.stopPx - 15) + ', ' + y1 + ' ' +\n      (r2.stopPx - 15) + ', ' + y2 + ' ' +\n      (r2.startPx - 15) + ', ' + y2\n    )\n    .style('fill', color)\n    .style('fill-opacity', opacity);\n}\n\nexport function getRegionsR1AndR2(regions, ideo, xOffset = null) {\n  var r1, r2,\n    r1Offset, r2Offset;\n\n  r1 = regions.r1;\n  r2 = regions.r2;\n\n  if (typeof r1.chr === 'string') {\n    const taxids = ideo.config.taxids;\n    if (ideo.config.multiorganism) {\n      r1.chr = ideo.chromosomes[taxids[0]][r1.chr];\n      r2.chr = ideo.chromosomes[taxids[1]][r2.chr];\n    } else {\n      r1.chr = ideo.chromosomes[taxids[0]][r1.chr];\n      r2.chr = ideo.chromosomes[taxids[0]][r2.chr];\n    }\n  }\n\n  var r1ChrDom = document.querySelector('#' + r1.chr.id + '-chromosome-set');\n  var r1GenomeHorizontalXOffset = r1ChrDom.getCTM().e;\n  var r1GenomeVerticalXOffset = r1ChrDom.getCTM().f;\n  var r2ChrDom = document.querySelector('#' + r2.chr.id + '-chromosome-set');\n  // var r2GenomeOffset = r2ChrDom.getBoundingClientRect().top;\n  var r2GenomeHorizontalXOffset = r2ChrDom.getCTM().e;\n  var r2GenomeVerticalXOffset = r2ChrDom.getCTM().f;\n\n  if (xOffset === null) {\n    if (ideo.config.orientation === 'vertical') {\n      // When vertical collinear\n      // http://localhost:8080/examples/vanilla/compare-whole-genomes?chromosome-scale=absolute&orientation=vertical\n      r1Offset = r1GenomeVerticalXOffset - 12;\n      r2Offset = r2GenomeVerticalXOffset - 12;\n    } else {\n      // When horizontal collinear, e.g.\n      // http://localhost:8080/examples/vanilla/compare-whole-genomes?chromosome-scale=absolute&orientation=horizontal\n      r1Offset = r1GenomeHorizontalXOffset;\n      r2Offset = r2GenomeHorizontalXOffset;\n    }\n  } else {\n    // When horizontal parallel\n    r1Offset = xOffset;\n    r2Offset = xOffset;\n  }\n\n  r1.startPx = ideo.convertBpToPx(r1.chr, r1.start) + r1Offset;\n  r1.stopPx = ideo.convertBpToPx(r1.chr, r1.stop) + r1Offset;\n  r2.startPx = ideo.convertBpToPx(r2.chr, r2.start) + r2Offset;\n  r2.stopPx = ideo.convertBpToPx(r2.chr, r2.stop) + r2Offset;\n\n  return [r1, r2];\n}\n","import {d3} from '../lib';\nimport {\n  getRegionsR1AndR2, writeSyntenicRegionPolygons, writeSyntenicRegion\n} from './synteny-lib';\n\nfunction writeSyntenicRegionLines(syntenicRegion, x1, x2, r1, r2) {\n  syntenicRegion.append('line')\n    .attr('class', 'syntenyBorder')\n    .attr('x1', x1)\n    .attr('x2', x2)\n    .attr('y1', r1.startPx)\n    .attr('y2', r2.startPx);\n\n  syntenicRegion.append('line')\n    .attr('class', 'syntenyBorder')\n    .attr('x1', x1)\n    .attr('x2', x2)\n    .attr('y1', r1.stopPx)\n    .attr('y2', r2.stopPx);\n}\n\nfunction writeSyntenicRegions(syntenicRegions, syntenies, ideo) {\n  var i, regions, r1, r2, regionID, syntenicRegion, chrWidth, x1, x2;\n\n  for (i = 0; i < syntenicRegions.length; i++) {\n    regions = syntenicRegions[i];\n\n    [r1, r2] = getRegionsR1AndR2(regions, ideo);\n\n    regionID = (\n      r1.chr.id + '_' + r1.start + '_' + r1.stop + '_' +\n      '__' +\n      r2.chr.id + '_' + r2.start + '_' + r2.stop\n    );\n\n    syntenicRegion = writeSyntenicRegion(syntenies, regionID, ideo);\n\n    chrWidth = ideo.config.chrWidth;\n    x1 = chrWidth + 46;\n    x2 = chrWidth + 240; // Genomes are spaced ~200 pixels apart\n\n    writeSyntenicRegionPolygons(syntenicRegion, x1, x2, r1, r2, regions);\n    writeSyntenicRegionLines(syntenicRegion, x1, x2, r1, r2);\n  }\n}\n\nfunction reportPerformance(t0, ideo) {\n  var t1 = new Date().getTime();\n  if (ideo.config.debug) {\n    console.log('Time in drawSyntenicRegions: ' + (t1 - t0) + ' ms');\n  }\n}\n\n/**\n * Draws a trapezoid connecting a genomic range on\n * one chromosome to a genomic range on another chromosome;\n * a syntenic region.\n */\nfunction drawSyntenyCollinear(syntenicRegions, ideo) {\n  var syntenies,\n    t0 = new Date().getTime();\n\n  syntenies = d3.select(ideo.selector)\n    .insert('g', ':first-child')\n    .attr('class', 'synteny');\n\n  writeSyntenicRegions(syntenicRegions, syntenies, ideo);\n\n  reportPerformance(t0, ideo);\n}\n\nexport {drawSyntenyCollinear};\n","import {d3} from '../lib';\nimport {\n  getRegionsR1AndR2, writeSyntenicRegionPolygonsHorizontal, writeSyntenicRegion\n} from './synteny-lib';\n\nfunction writeSyntenicRegionLines(syntenicRegion, y1, y2, r1, r2) {\n  syntenicRegion.append('line')\n    .attr('class', 'syntenyBorder')\n    .attr('x1', r1.startPx - 15)\n    .attr('x2', r2.startPx - 15)\n    .attr('y1', y1)\n    .attr('y2', y2);\n\n  syntenicRegion.append('line')\n    .attr('class', 'syntenyBorder')\n    .attr('x1', r1.stopPx - 15)\n    .attr('x2', r2.stopPx - 15)\n    .attr('y1', y1)\n    .attr('y2', y2);\n}\n\nfunction writeSyntenicRegions(syntenicRegions, syntenies, ideo) {\n  var i, regions, r1, r2, regionID, syntenicRegion, chrWidth, y1, y2;\n\n  for (i = 0; i < syntenicRegions.length; i++) {\n    regions = syntenicRegions[i];\n\n    [r1, r2] = getRegionsR1AndR2(regions, ideo);\n\n    regionID = (\n      r1.chr.id + '_' + r1.start + '_' + r1.stop + '_' +\n      '__' +\n      r2.chr.id + '_' + r2.start + '_' + r2.stop\n    );\n\n    syntenicRegion = writeSyntenicRegion(syntenies, regionID, ideo);\n\n    chrWidth = ideo.config.chrWidth;\n    y1 = chrWidth + 31;\n    y2 = chrWidth + 191; // Genomes are spaced ~200 pixels apart\n\n    writeSyntenicRegionPolygonsHorizontal(\n      syntenicRegion, y1, y2, r1, r2, regions\n    );\n    writeSyntenicRegionLines(syntenicRegion, y1, y2, r1, r2);\n  }\n}\n\nfunction reportPerformance(t0, ideo) {\n  var t1 = new Date().getTime();\n  if (ideo.config.debug) {\n    console.log('Time in drawSyntenicRegions: ' + (t1 - t0) + ' ms');\n  }\n}\n\n/**\n * Draws a trapezoid connecting a genomic range on\n * one chromosome to a genomic range on another chromosome;\n * a syntenic region.\n */\nfunction drawSyntenyCollinearHorizontal(syntenicRegions, ideo) {\n  var syntenies,\n    t0 = new Date().getTime();\n\n  syntenies = d3.select(ideo.selector)\n    .insert('g', ':first-child')\n    .attr('class', 'synteny');\n\n  writeSyntenicRegions(syntenicRegions, syntenies, ideo);\n\n  reportPerformance(t0, ideo);\n}\n\nexport {drawSyntenyCollinearHorizontal};\n","import {d3} from '../lib';\nimport {drawSyntenyCollinear} from './synteny-collinear';\nimport {drawSyntenyCollinearHorizontal} from './synteny-collinear-horizontal';\nimport {\n  getRegionsR1AndR2, writeSyntenicRegionPolygons, writeSyntenicRegion\n} from './synteny-lib';\n\nfunction writeSyntenicRegionLines(syntenicRegion, x1, x2, r1, r2, regions) {\n\n  var stroke, width;\n  if (\n    Math.abs(r1.startPx - r1.startPx) < 2 &&\n    Math.abs(r1.stopPx - r1.stopPx) < 2\n  ) {\n    stroke = regions.color;\n    width = regions.width;\n  } else {\n    stroke = '';\n    width = '';\n  }\n\n  syntenicRegion.append('line')\n    .attr('class', 'syntenyBorder')\n    .attr('x1', x1)\n    .attr('x2', x2)\n    .attr('y1', r1.startPx)\n    .attr('y2', r2.startPx)\n    .style('stroke', stroke)\n    .style('stroke-width', width);\n\n  syntenicRegion.append('line')\n    .attr('class', 'syntenyBorder')\n    .attr('x1', x1)\n    .attr('x2', x2)\n    .attr('y1', r1.stopPx)\n    .attr('y2', r2.stopPx)\n    .style('stroke', stroke)\n    .style('stroke-width', stroke);\n}\n\nfunction writeSyntenicRegionLabels(syntenicRegion, x1, x2, r1, r2, regionId) {\n  var rangeIds = regionId.split('__').map(d => 'label_' + d);\n  if ('name' in r1) {\n    syntenicRegion.append('text')\n      .attr('id', rangeIds[0])\n      .attr('y', r1.startPx + 3)\n      .text(r1.name);\n    var r1Width =\n      document.querySelector('#' + rangeIds[0]).getBoundingClientRect().width;\n    d3.select('#' + rangeIds[0]).attr('x', x1 - 15 - r1Width);\n  }\n  if ('name' in r2) {\n    syntenicRegion.append('text')\n      .attr('id', rangeIds[1])\n      .text(r2.name)\n      .attr('x', x2 + 15)\n      .attr('y', r2.startPx + 3)\n      .text(r2.name);\n  }\n}\n\nfunction writeSyntenicRegions(syntenicRegions, syntenies, xOffset, ideo) {\n  var i, regions, r1, r2, regionID, syntenicRegion, chrWidth, x1, x2;\n\n  for (i = 0; i < syntenicRegions.length; i++) {\n    regions = syntenicRegions[i];\n\n    [r1, r2] = getRegionsR1AndR2(regions, ideo, xOffset);\n\n    regionID = (\n      r1.chr.id + '_' + r1.start + '_' + r1.stop + '_' +\n      '__' +\n      r2.chr.id + '_' + r2.start + '_' + r2.stop\n    );\n\n    syntenicRegion = writeSyntenicRegion(syntenies, regionID, ideo);\n\n    chrWidth = ideo.config.chrWidth;\n    x1 = ideo._layout.getChromosomeSetYTranslate(0);\n    x2 = ideo._layout.getChromosomeSetYTranslate(1) - chrWidth;\n\n    writeSyntenicRegionPolygons(syntenicRegion, x1, x2, r1, r2, regions);\n    writeSyntenicRegionLines(syntenicRegion, x1, x2, r1, r2, regions);\n    writeSyntenicRegionLabels(syntenicRegion, x1, x2, r1, r2, regionID);\n  }\n}\n\nfunction reportPerformance(t0, ideo) {\n  var t1 = new Date().getTime();\n  if (ideo.config.debug) {\n    console.log('Time in drawSyntenicRegions: ' + (t1 - t0) + ' ms');\n  }\n}\n\n/**\n * Draws a trapezoid connecting a genomic range on\n * one chromosome to a genomic range on another chromosome;\n * a syntenic region.\n */\nfunction drawSynteny(syntenicRegions) {\n  var syntenies, xOffset,\n    t0 = new Date().getTime(),\n    ideo = this,\n    config = ideo.config;\n\n  if (\n    config.multiorganism &&\n    config.geometry === 'collinear'\n  ) {\n    if (config.orientation === 'vertical') {\n      return drawSyntenyCollinear(syntenicRegions, ideo);\n    } else {\n      return drawSyntenyCollinearHorizontal(syntenicRegions, ideo);\n    }\n  }\n\n  syntenies = d3.select(ideo.selector)\n    .insert('g', ':first-child')\n    .attr('class', 'synteny');\n\n  xOffset = ideo._layout.margin.left;\n\n  writeSyntenicRegions(syntenicRegions, syntenies, xOffset, ideo);\n\n  reportPerformance(t0, ideo);\n}\n\nexport {drawSynteny};\n","import {d3} from '../lib';\nimport collinearizeChromosomes from '../collinear';\n\n/**\n * Reset displayed tracks to those originally displayed\n */\nfunction restoreDefaultTracks() {\n  var ideo = this;\n  ideo.config.numAnnotTracks = ideo.config.annotationsNumTracks;\n  d3.selectAll(ideo.selector + ' .annot').remove();\n  ideo.drawAnnots(ideo.processAnnotData(ideo.rawAnnots));\n}\n\nfunction getDisplayedRawAnnotsByChr(annotsByChr, trackIndexes) {\n  var annot, displayedRawAnnotsByChr, annots, i, displayedAnnots, j,\n    trackIndex;\n\n  displayedRawAnnotsByChr = [];\n\n  // Filter displayed tracks by selected track indexes\n  for (i = 0; i < annotsByChr.length; i++) {\n    annots = annotsByChr[i];\n    displayedAnnots = [];\n    for (j = 0; j < annots.annots.length; j++) {\n      annot = annots.annots[j].slice(); // copy array by value\n      trackIndex = annot[3] + 1;\n      if (trackIndexes.includes(trackIndex)) {\n        annot[3] = trackIndexes.indexOf(trackIndex);\n        displayedAnnots.push(annot);\n      }\n    }\n    displayedRawAnnotsByChr.push({chr: annots.chr, annots: displayedAnnots});\n  }\n\n  return displayedRawAnnotsByChr;\n}\n\n/**\n * Adds or removes tracks from the displayed list of tracks.\n * Only works when raw annotations are dense.\n *\n * @param trackIndexes Array of indexes of tracks to display\n */\nfunction updateDisplayedTracks(trackIndexes) {\n  var displayedRawAnnotsByChr, displayedAnnots, rawAnnots,\n    ideo = this,\n    annotsByChr = ideo.rawAnnots.annots;\n\n  ideo.config.numAnnotTracks = trackIndexes.length;\n\n  displayedRawAnnotsByChr =\n    getDisplayedRawAnnotsByChr(annotsByChr, trackIndexes);\n  rawAnnots = {keys: ideo.rawAnnots.keys, annots: displayedRawAnnotsByChr};\n\n  if (ideo.config.geometry === 'collinear') {\n    collinearizeChromosomes(ideo);\n  }\n\n  displayedAnnots = ideo.processAnnotData(rawAnnots);\n\n  d3.selectAll(ideo.selector + ' .annot').remove();\n  ideo.displayedTrackIndexes = trackIndexes;\n  ideo.drawAnnots(displayedAnnots);\n\n  return displayedAnnots;\n}\n\nfunction getSetAnnotsByChr(annotsByChr, ideo) {\n  var i, j, annots, annot, setAnnots, trackIndexOriginal, numAvailTracks,\n    setAnnotsByChr = [];\n\n  numAvailTracks = 1;\n\n  for (i = 0; i < annotsByChr.length; i++) {\n    annots = annotsByChr[i];\n    setAnnots = [];\n    for (j = 0; j < annots.annots.length; j++) {\n      annot = annots.annots[j].slice();\n      trackIndexOriginal = annot[3];\n      if (trackIndexOriginal + 1 > numAvailTracks) {\n        numAvailTracks = trackIndexOriginal + 1;\n      }\n      annot.splice(4, 0, trackIndexOriginal);\n      setAnnots.push(annot);\n    }\n    setAnnotsByChr.push({chr: annots.chr, annots: setAnnots});\n  }\n\n  ideo.numAvailTracks = numAvailTracks;\n\n  return setAnnotsByChr;\n}\n\nfunction setOriginalTrackIndexes(rawAnnots) {\n  var keys, annotsByChr, setAnnotsByChr,\n    ideo = this;\n\n  keys = rawAnnots.keys;\n\n  // If this method is unnecessary, pass through\n  if (\n    keys.length < 4 ||\n    keys[3] !== 'trackIndex' ||\n    keys[4] === 'trackIndexOriginal'\n  ) {\n    return rawAnnots;\n  }\n\n  annotsByChr = rawAnnots.annots;\n  setAnnotsByChr = getSetAnnotsByChr(annotsByChr, ideo);\n\n  keys.splice(4, 0, 'trackIndexOriginal');\n  rawAnnots = {keys: keys, annots: setAnnotsByChr};\n  if (ideo.rawAnnots.metadata) rawAnnots.metadata = ideo.rawAnnots.metadata;\n\n  return rawAnnots;\n}\n\nexport {restoreDefaultTracks, setOriginalTrackIndexes, updateDisplayedTracks};\n","import {add2dAnnotsForChr} from './heatmap-2d';\n\n// Default colors for tracks of annotations\nvar colorMap = [\n  ['F00'], // If there is 1 track, then color it red.\n  ['F00', '88F'], // If 2 tracks, color one red and one light blue.\n  ['F00', 'CCC', '88F'], // If 3, color one red, one grey, one light blue.\n  ['F00', 'FA0', '0AF', '88F'], // And so on.\n  ['F00', 'FA0', 'CCC', '0AF', '88F'],\n  ['F00', 'FA0', '875', '578', '0AF', '88F'],\n  ['F00', 'FA0', '875', 'CCC', '578', '0AF', '88F'],\n  ['F00', 'FA0', '7A0', '875', '0A7', '578', '0AF', '88F'],\n  ['F00', 'FA0', '7A0', '875', 'CCC', '0A7', '578', '0AF', '88F'],\n  ['F00', 'FA0', '7A0', '875', '552', '255', '0A7', '578', '0AF', '88F']\n];\n\n/**\n * Ensure annotation containers are ordered by chromosome.\n */\nfunction orderAnnotContainers(annots, ideo) {\n  var unorderedAnnots, i, j, annot, chr, chrs;\n\n  unorderedAnnots = annots;\n  annots = [];\n  chrs = ideo.chromosomesArray;\n  for (i = 0; i < chrs.length; i++) {\n    chr = chrs[i].name;\n    for (j = 0; j < unorderedAnnots.length; j++) {\n      annot = unorderedAnnots[j];\n      if (annot.chr === chr) {\n        annots.push(annot);\n      }\n    }\n  }\n\n  return annots;\n}\n\n/**\n * Add client annotations, as in annotations-tracks.html\n */\nfunction addClientAnnot(annots, annot, ra, m, ideo) {\n  var annotTrack;\n\n  annot.trackIndex = ra[3];\n  annotTrack = ideo.config.annotationTracks[annot.trackIndex];\n  if (annotTrack.color) {\n    annot.color = annotTrack.color;\n  }\n  if (annotTrack.shape) {\n    annot.shape = annotTrack.shape;\n  }\n\n  annots[m].annots.push(annot);\n\n  return annots;\n}\n\n/**\n * Add sparse server annotations, as in annotations-track-filters.html\n */\nfunction addSparseServerAnnot(annot, ra, omittedAnnots, annots, m, ideo) {\n  var colors = colorMap[ideo.numAvailTracks - 1];\n\n  annot.trackIndex = ra[3];\n  annot.trackIndexOriginal = ra[4];\n  annot.color = '#' + colors[annot.trackIndexOriginal];\n\n  // Catch annots that will be omitted from display\n  if (annot.trackIndex > ideo.config.numTracks - 1) {\n    if (annot.trackIndex in omittedAnnots) {\n      omittedAnnots[annot.trackIndex].push(annot);\n    } else {\n      omittedAnnots[annot.trackIndex] = [annot];\n    }\n    return [annots, omittedAnnots];\n  }\n  annots[m].annots.push(annot);\n\n  return [annots, omittedAnnots];\n}\n\n/**\n * Basic client annotations, as in annotations-basic.html\n * and annotations-external.html\n */\nfunction addBasicClientAnnot(annots, annot, m, ideo) {\n  annot.trackIndex = 0;\n  if (!annot.color) {\n    annot.color = ideo.config.annotationsColor;\n  }\n  if (!annot.shape) {\n    annot.shape = 'triangle';\n  }\n  annots[m].annots.push(annot);\n\n  return annots;\n}\n\nfunction addAnnot(annot, keys, ra, omittedAnnots, annots, m, ideo) {\n\n  if (ideo.config.annotationTracks) {\n    annots = addClientAnnot(annots, annot, ra, m, ideo);\n  } else if (keys[3] === 'trackIndex' && ideo.numAvailTracks !== 1) {\n    [annots, omittedAnnots] =\n      addSparseServerAnnot(annot, ra, omittedAnnots, annots, m, ideo);\n  // } else if (\n  //   keys.length > 3 &&\n  //   keys[3] in {trackIndex: 1, color: 1, shape: 1} === false &&\n  //   keys[4] === 'trackIndexOriginal'\n  // ) {\n  //   annots = addDenseServerAnnot(keys, annots, annot, m);\n  } else {\n    annots = addBasicClientAnnot(annots, annot, m, ideo);\n  }\n\n  return [annots, omittedAnnots];\n}\n\nfunction addAnnotsForChr(annots, omittedAnnots, annotsByChr, chrModel,\n  m, keys, ideo) {\n  var j, k, annot, ra;\n\n  for (j = 0; j < annotsByChr.annots.length; j++) {\n    ra = annotsByChr.annots[j];\n    annot = {};\n\n    for (k = 0; k < keys.length; k++) {\n      annot[keys[k]] = ra[k];\n    }\n\n    annot.stop = annot.start + annot.length;\n\n    annot.chr = annotsByChr.chr;\n    annot.chrIndex = m;\n    annot.startPx = ideo.convertBpToPx(chrModel, annot.start);\n    annot.stopPx = ideo.convertBpToPx(chrModel, annot.stop);\n    annot.px = Math.round((annot.startPx + annot.stopPx) / 2);\n\n    [annots, omittedAnnots] =\n      addAnnot(annot, keys, ra, omittedAnnots, annots, m, ideo);\n  }\n\n  return [annots, omittedAnnots];\n}\n\nfunction warnOfUndefinedChromosome(annotsByChr) {\n  console.warn(\n    'Chromosome \"' + annotsByChr.chr + '\" undefined in ideogram; ' +\n    annotsByChr.annots.length + ' annotations not shown'\n  );\n}\n\nfunction addAnnots(rawAnnots, keys, ideo) {\n  var m, i, annotsByChr, chrModel,\n    annots = [],\n    omittedAnnots = {};\n\n  m = -1;\n  for (i = 0; i < rawAnnots.length; i++) {\n    annotsByChr = rawAnnots[i];\n    chrModel = ideo.chromosomes[ideo.config.taxid][annotsByChr.chr];\n\n    if (typeof chrModel === 'undefined') {\n      warnOfUndefinedChromosome(annotsByChr);\n      continue;\n    }\n\n    m++;\n    annots.push({chr: annotsByChr.chr, annots: []});\n\n    if (ideo.config.annotationsLayout !== 'heatmap-2d') {\n      [annots, omittedAnnots] =\n        addAnnotsForChr(annots, omittedAnnots, annotsByChr, chrModel, m,\n          keys, ideo);\n    } else {\n      [annots, omittedAnnots] =\n        add2dAnnotsForChr(annots, omittedAnnots, annotsByChr, chrModel, m,\n          keys, ideo);\n    }\n  }\n  return [annots, omittedAnnots];\n}\n\nfunction sendTrackAndAnnotWarnings(omittedAnnots, ideo) {\n  var numOmittedTracks,\n    layout = ideo.config.annotationsLayout,\n    numTracks = ideo.config.numAnnotTracks;\n\n  if (!/heatmap/.test(layout) && numTracks > 10) {\n    console.error(\n      'Ideogram only displays up to 10 tracks at a time.  ' +\n      'You specified ' + numTracks + ' tracks.  ' +\n      'Perhaps consider a different way to visualize your data.'\n    );\n  }\n\n  numOmittedTracks = Object.keys(omittedAnnots).length;\n  if (numOmittedTracks) {\n    console.warn(\n      'Ideogram configuration specified ' + numTracks + ' tracks, ' +\n      'but loaded annotations contain ' + numOmittedTracks + ' ' +\n      'extra tracks.'\n    );\n  }\n}\n\n/**\n * Proccesses genome annotation data.\n *\n * This method converts raw annotation data from server, which is structured as\n * an array of arrays, into a more verbose data structure consisting of an\n * array of objects.  It also adds pixel offset information.\n */\nfunction processAnnotData(rawAnnots) {\n  var keys, annots, omittedAnnots,\n    ideo = this;\n\n  keys = rawAnnots.keys;\n  rawAnnots = rawAnnots.annots;\n\n  [annots, omittedAnnots] = addAnnots(rawAnnots, keys, ideo);\n  annots = orderAnnotContainers(annots, ideo);\n\n  sendTrackAndAnnotWarnings(omittedAnnots, ideo);\n\n  return annots;\n}\n\nexport {processAnnotData};\n","/**\n * @fileoverview Parse raw Ideogram.js annotations from an expression matrix.\n * This module handles dense gene expression matrixes.\n * In gene expression expressions, rows are genes and columns are cells.\n */\n\nexport class ExpressionMatrixParser {\n\n  /**\n   * @param {String} matrix Tab-delimited gene expression matrix\n   * @param {Object} coordinates Coordinates [chr, start, length] by gene name\n   * @param {Object} ideo Ideogram object\n   */\n  constructor(matrix, ideo) {\n    this.matrix = matrix;\n    this.ideo = ideo;\n  }\n\n  /**\n   * Initialize rawAnnots by fetching genomic coordinates, then merging them\n   * with the gene expression matrix supplied in constructor.\n   */\n  setRawAnnots() {\n    var parser, ideo, matrix;\n    parser = this;\n    ideo = this.ideo;\n    matrix = this.matrix;\n\n    return new Promise(function(resolve) {\n      parser.rawAnnots = parser.fetchCoordinates(ideo)\n        .then(function(coordinates) {\n          parser.coordinates = coordinates;\n          resolve(parser.parseExpressionMatrix(matrix, ideo));\n        });\n    });\n  }\n\n  /**\n   * Get chromosome, start and stop coordinates from genome annotation file\n   *\n   * TODO: Support non-human organisms\n   */\n  fetchCoordinates(ideo) {\n    var coordinates = {};\n\n    if (ideo.config.organism === 'human') {\n      var ensemblData =\n        ideo.config.dataDir +\n        '../../annotations/Homo_sapiens,_Ensembl_80.tsv';\n\n      return new Promise(function(resolve) {\n        ideo.fetch(ensemblData, 'text').then(function(data) {\n          // eslint-disable-next-line no-unused-vars\n          var tsvLines, i, start, stop, gene, chr, length, geneType;\n\n          tsvLines = data.split(/\\r\\n|\\n/).slice(1);\n          for (i = 0; i < tsvLines.length; i++) {\n            [start, stop, gene, geneType, chr] = tsvLines[i].split(/\\s/g);\n            start = parseInt(start);\n            stop = parseInt(stop);\n            length = stop - start;\n            coordinates[gene] = [chr, start, length];\n          }\n          resolve(coordinates);\n        });\n      });\n    } else {\n      throw Error('Expression matrix parsing is only supported for human');\n    }\n  }\n\n  /**\n   * Parses an annotation from a tab-separated line of a matrix file\n   */\n  parseAnnotFromTsvLine(tsvLine, chrs) {\n    var annot, chrIndex, chr, start, gene, expressions,\n      columns = tsvLine.split(/\\s/g);\n\n    gene = columns[0];\n    if (gene in this.coordinates === false) return [null, null];\n\n    expressions = columns.slice(1).map(d => parseFloat(d));\n    [chr, start, length] = this.coordinates[gene];\n\n    chrIndex = chrs.indexOf(chr);\n    if (chrIndex === -1) return [null, null];\n\n    annot = [gene, start, length];\n    annot = annot.concat(expressions);\n\n    return [chrIndex, annot];\n  }\n\n  /**\n  * Parses a gene expression matrix file, returns raw annotations\n  */\n  parseExpressionMatrix(matrix, ideo) {\n    var i, chrs, rawAnnots, cells, line, chrIndex, annot, keys,\n      annots = [],\n      tsvLines = matrix.split(/\\r\\n|\\n/);\n\n    chrs = Object.keys(ideo.chromosomes[ideo.config.taxid]);\n    for (i = 0; i < chrs.length; i++) {\n      annots.push({chr: chrs[i], annots: []});\n    }\n\n    for (i = 1; i < tsvLines.length; i++) {\n      line = tsvLines[i];\n      [chrIndex, annot] = this.parseAnnotFromTsvLine(line, chrs);\n      if (chrIndex !== null) annots[chrIndex].annots.push(annot);\n    }\n\n    cells = tsvLines[0].split(/\\s/g);\n    keys = ['name', 'start', 'length'].concat(cells);\n    rawAnnots = {keys: keys, annots: annots};\n\n    return rawAnnots;\n  }\n\n}\n","/**\n * @fileoverview Methods for ideogram annotations.\n * Annotations are graphical objects that represent features of interest\n * located on the chromosomes, e.g. genes or variations.  They can\n * appear beside a chromosome, overlaid on top of it, or between multiple\n * chromosomes.\n */\n\nimport {BedParser} from '../parsers/bed-parser';\nimport {drawHeatmaps, deserializeAnnotsForHeatmap} from './heatmap';\nimport {inflateThresholds} from './heatmap-lib';\nimport {inflateHeatmaps} from './heatmap-collinear';\nimport {\n  onLoadAnnots, onDrawAnnots, startHideAnnotTooltipTimeout,\n  onWillShowAnnotTooltip, showAnnotTooltip, onClickAnnot\n} from './events';\nimport {drawAnnots, drawProcessedAnnots} from './draw';\nimport {getHistogramBars} from './histogram';\nimport {drawSynteny} from './synteny';\nimport {\n  restoreDefaultTracks, setOriginalTrackIndexes, updateDisplayedTracks\n} from './filter';\nimport {processAnnotData} from './process';\nimport {ExpressionMatrixParser} from '../parsers/expression-matrix-parser';\n\nfunction initNumTracksAndBarWidth(ideo, config) {\n\n  if (config.annotationTracks) {\n    ideo.config.numAnnotTracks = config.annotationTracks.length;\n  } else if (config.annotationsNumTracks) {\n    ideo.config.numAnnotTracks = config.annotationsNumTracks;\n  } else {\n    ideo.config.numAnnotTracks = 1;\n  }\n  ideo.config.annotTracksHeight =\n    config.annotationHeight * config.numAnnotTracks;\n\n  if (typeof config.barWidth === 'undefined') {\n    ideo.config.barWidth = 3;\n  }\n}\n\nfunction initTooltip(ideo, config) {\n  if (config.showAnnotTooltip !== false) {\n    ideo.config.showAnnotTooltip = true;\n  }\n\n  if (config.onWillShowAnnotTooltip) {\n    ideo.onWillShowAnnotTooltipCallback = config.onWillShowAnnotTooltip;\n  }\n}\n\nfunction initAnnotHeight(ideo) {\n  var config = ideo.config;\n  var annotHeight;\n\n  if (!config.annotationHeight) {\n    if (config.annotationsLayout === 'heatmap') {\n      annotHeight = config.chrWidth - 1;\n    } else {\n      annotHeight = Math.round(config.chrHeight / 100);\n      if (annotHeight < 3) annotHeight = 3;\n    }\n    ideo.config.annotationHeight = annotHeight;\n  }\n}\n\n/**\n * Initializes various annotation settings.  Constructor help function.\n */\nfunction initAnnotSettings() {\n  var ideo = this,\n    config = ideo.config;\n\n  initAnnotHeight(ideo);\n\n  if (\n    config.annotationsPath || config.localAnnotationsPath ||\n    ideo.annots || config.annotations\n  ) {\n    initNumTracksAndBarWidth(ideo, config);\n  } else {\n    ideo.config.annotTracksHeight = 0;\n    ideo.config.numAnnotTracks = 0;\n  }\n\n  if (typeof config.annotationsColor === 'undefined') {\n    ideo.config.annotationsColor = '#F00';\n  }\n\n  if (config.onClickAnnot) {\n    ideo.onClickAnnotCallback = config.onClickAnnot;\n  }\n\n  initTooltip(ideo, config);\n}\n\nfunction validateAnnotsUrl(annotsUrl) {\n  var tmp, extension;\n\n  tmp = annotsUrl.split('?')[0].split('.');\n  extension = tmp[tmp.length - 1];\n\n  if (extension !== 'bed' && extension !== 'json') {\n    extension = extension.toUpperCase();\n    alert(\n      'Ideogram.js only supports BED and Ideogram JSON at the moment.  ' +\n      'Sorry, check back soon for ' + extension + ' support!'\n    );\n    return;\n  }\n  return extension;\n}\n\nfunction afterRawAnnots() {\n  var ideo = this,\n    config = ideo.config;\n  // Ensure annots are ordered by chromosome\n  ideo.rawAnnots.annots = ideo.rawAnnots.annots.sort(function(a, b) {\n    return a.chr.localeCompare(b.chr, 'en', {numeric: true});\n  });\n\n  if (ideo.onLoadAnnotsCallback) {\n    ideo.onLoadAnnotsCallback();\n  }\n\n  if (\n    'heatmapThresholds' in config ||\n    'metadata' in ideo.rawAnnots &&\n    'heatmapThresholds' in ideo.rawAnnots.metadata\n  ) {\n    if (config.annotationsLayout === 'heatmap') {\n      inflateHeatmaps(ideo);\n    } else if (config.annotationsLayout === 'heatmap-2d') {\n      ideo.config.heatmapThresholds = inflateThresholds(ideo);\n    }\n  }\n\n  if (config.heatmaps) {\n    ideo.deserializeAnnotsForHeatmap(ideo.rawAnnots);\n  }\n}\n\n/**\n * Requests annotations URL via HTTP, sets ideo.rawAnnots for downstream\n * processing.\n *\n * @param annotsUrl Absolute or relative URL for native or BED annotations file\n */\nfunction fetchAnnots(annotsUrl) {\n  var extension, is2dHeatmap,\n    ideo = this,\n    config = ideo.config;\n\n  is2dHeatmap = config.annotationsLayout === 'heatmap-2d';\n\n  if (annotsUrl.slice(0, 4) !== 'http' && !is2dHeatmap) {\n    ideo.fetch(annotsUrl)\n      .then(function(data) {\n        ideo.rawAnnotsResponse = data; // Preserve truly raw response content\n        ideo.rawAnnots = data; // Sometimes gets partially processed\n        ideo.afterRawAnnots();\n      });\n    return;\n  }\n\n  extension = (is2dHeatmap ? '' : validateAnnotsUrl(annotsUrl));\n\n  ideo.fetch(annotsUrl, 'text')\n    .then(function(text) {\n      ideo.rawAnnotsResponse = text;\n      if (is2dHeatmap) {\n        var parser = new ExpressionMatrixParser(text, ideo);\n        parser.setRawAnnots().then(function(d) {\n          ideo.rawAnnots = d;\n          ideo.afterRawAnnots();\n        });\n      } else {\n        if (extension === 'bed') {\n          ideo.rawAnnots = new BedParser(text, ideo).rawAnnots;\n        } else {\n          ideo.rawAnnots = JSON.parse(text);\n        }\n        ideo.afterRawAnnots();\n      }\n    });\n}\n\n/**\n * Fills out annotations data structure such that its top-level list of arrays\n * matches that of this ideogram's chromosomes list in order and number\n * Fixes https://github.com/eweitz/ideogram/issues/66\n */\nfunction fillAnnots(annots) {\n  var filledAnnots, chrs, chrArray, i, chr, annot, chrIndex;\n\n  filledAnnots = [];\n  chrs = [];\n  chrArray = this.chromosomesArray;\n\n  for (i = 0; i < chrArray.length; i++) {\n    chr = chrArray[i].name;\n    chrs.push(chr);\n    filledAnnots.push({chr: chr, annots: []});\n  }\n\n  for (i = 0; i < annots.length; i++) {\n    annot = annots[i];\n    chrIndex = chrs.indexOf(annot.chr);\n    if (chrIndex !== -1) {\n      filledAnnots[chrIndex] = annot;\n    }\n  }\n\n  return filledAnnots;\n}\n\nexport {\n  onLoadAnnots, onDrawAnnots, processAnnotData, restoreDefaultTracks,\n  updateDisplayedTracks, initAnnotSettings, fetchAnnots, drawAnnots,\n  getHistogramBars, drawHeatmaps, deserializeAnnotsForHeatmap, fillAnnots,\n  drawProcessedAnnots, drawSynteny, startHideAnnotTooltipTimeout,\n  showAnnotTooltip, onWillShowAnnotTooltip, setOriginalTrackIndexes,\n  afterRawAnnots, onClickAnnot\n};\n","import {d3, slug} from '../lib';\n\n/**\n *  Returns NCBI Taxonomy identifier (taxid) for organism name\n */\nfunction getTaxidFromEutils(orgName, ideo) {\n  var taxonomySearch, taxid;\n\n  taxonomySearch = ideo.esearch + '&db=taxonomy&term=' + orgName;\n\n  return d3.json(taxonomySearch).then(function(data) {\n    taxid = data.esearchresult.idlist[0];\n    return [orgName, taxid];\n  });\n}\n\n/**\n * Returns organism common name given an NCBI Taxonomy ID\n *\n * @param taxid NCBI Taxonomy ID\n * @param callback Function to call upon completing ESearch request\n */\nfunction getOrganismFromEutils(taxid, callback) {\n  var organism, taxonomySearch,\n    ideo = this;\n\n  taxid = ideo.config.organism;\n\n  taxonomySearch = ideo.esummary + '&db=taxonomy&id=' + taxid;\n\n  d3.json(taxonomySearch).then(function(data) {\n    organism = data.result[String(taxid)].commonname;\n    ideo.config.organism = organism;\n    return callback(organism);\n  });\n}\n\nfunction setTaxidData(taxid, ideo) {\n\n  var dataDir, urlOrg, taxids;\n\n  if (ideo.assemblyIsAccession()) {\n    return new Promise(function(resolve) {\n      ideo.coordinateSystem = 'bp';\n      ideo.getAssemblyAndChromosomesFromEutils(taxid, resolve);\n    });\n  }\n\n  dataDir = ideo.config.dataDir;\n  urlOrg = slug(ideo.organisms[taxid].scientificName);\n\n  taxids = [taxid];\n\n  var fullyBandedTaxids = ['9606', '10090', '10116'];\n  if (fullyBandedTaxids.includes(taxid) && !ideo.config.showFullyBanded) {\n    urlOrg += '-no-bands';\n  }\n  var chromosomesUrl = dataDir + urlOrg + '.json';\n\n  var promise2 = new Promise(function(resolve, reject) {\n    fetch(chromosomesUrl).then(function(response) {\n      if (response.ok === false) {\n        reject(Error('Fetch failed for ' + chromosomesUrl));\n      } else {\n        return response.json().then(function(json) {\n          resolve(json.chrBands);\n        });\n      }\n    });\n  });\n\n  return promise2\n    .then(function(chrBands) {\n      // Check if chromosome data exists locally.\n      // This is used for pre-processed centromere data,\n      // which is not accessible via EUtils.  See get_chromosomes.py.\n\n      var asmAndChrTaxidsArray = [''],\n        chromosomes = [],\n        seenChrs = {},\n        chr, maxLength, splitBand, length;\n\n      ideo.bandData[taxid] = chrBands;\n\n      for (var i = 0; i < chrBands.length; i++) {\n        splitBand = chrBands[i].split(' ');\n        chr = splitBand[0];\n        length = splitBand.slice(-1)[0];\n        if (chr in seenChrs) {\n          continue;\n        } else {\n          chromosomes.push({name: chr, type: 'nuclear', length: length});\n          seenChrs[chr] = 1;\n        }\n      }\n      chromosomes = chromosomes.sort(Ideogram.sortChromosomes);\n      maxLength = {bp: 0, iscn: 0};\n      chromosomes.forEach(chr => {\n        if (chr.length > maxLength.bp) maxLength.bp = chr.length;\n      });\n      ideo.maxLength[taxid] = maxLength;\n      asmAndChrTaxidsArray.push(chromosomes);\n      asmAndChrTaxidsArray.push(taxids);\n      return asmAndChrTaxidsArray;\n    },\n    function() {\n      // If request in `then` errs (404), fetch data from EUtils\n      return new Promise(function(resolve) {\n        ideo.coordinateSystem = 'bp';\n        ideo.getAssemblyAndChromosomesFromEutils(taxid, resolve);\n      });\n    });\n}\n\nfunction setAssemblyAndChromosomes(taxid, resolve, ideo) {\n  var assembly, chrs, originalChrs, orgName, filteredChrs,\n    config = ideo.config;\n\n  setTaxidData(taxid, ideo)\n    .then(function(asmChrTaxidsArray) {\n      assembly = asmChrTaxidsArray[0];\n      chrs = asmChrTaxidsArray[1];\n\n      if ('chromosomes' in config === false || config.chromosomes === null) {\n        ideo.config.chromosomes = {};\n        ideo.config.chromosomes[taxid] = chrs;\n      } else {\n        if (config.multiorganism) {\n          if (taxid in config.chromosomes) {\n            // Encountered when either organism has centromere data\n            originalChrs = config.chromosomes[taxid];\n          } else {\n            // Encountered when neither organism has centromere data\n            orgName = slug(ideo.getScientificName(taxid));\n            ideo.config.chromosomes[taxid] =\n              config.chromosomes[orgName].slice();\n            originalChrs = ideo.config.chromosomes[taxid];\n            // delete ideo.config.chromosomes[orgName];\n          }\n        } else {\n          originalChrs = config.chromosomes;\n        }\n\n        filteredChrs = chrs.filter(d => originalChrs.includes(d.name));\n        ideo.config.chromosomes[taxid] = filteredChrs;\n      }\n      ideo.chromosomes[taxid] = ideo.config.chromosomes[taxid].slice();\n      ideo.organisms[taxid].assemblies = {\n        default: assembly\n      };\n      resolve();\n    });\n}\n\n/**\n * Determine if organism is natively supported, using its name.\n */\nfunction isOrganismSupported(org, ideo) {\n  var taxid, ideoOrg;\n\n  for (taxid in ideo.organisms) {\n    ideoOrg = ideo.organisms[taxid];\n    if (\n      taxid === slug(org) ||\n      slug(ideoOrg.commonName) === slug(org) ||\n      slug(ideoOrg.scientificName) === slug(org)\n    ) {\n      return true;\n    }\n  }\n\n  return false;\n}\n\n/**\n * Augment \"organisms\" metadata with for any requested organism that is\n * not natively supported (i.e., not in organism-metadata.js).\n*/\nfunction populateNonNativeOrg(orgs, ideo) {\n  var org, promise, i,\n    getTaxidFromEutilsPromises = [],\n    augmentedOrganismMetadata = {};\n\n  for (i = 0; i < orgs.length; i++) {\n    org = orgs[i];\n    if (isOrganismSupported(org, ideo) === false) {\n      promise = getTaxidFromEutils(org, ideo)\n        .then(function(orgNameAndTaxid) {\n\n          var taxid = orgNameAndTaxid[1],\n            orgName = orgNameAndTaxid[0],\n            name, scientificName;\n\n          name = orgName.replace('-', ' ');\n          scientificName = name[0].toUpperCase() + name.slice(1);\n\n          augmentedOrganismMetadata[taxid] = {\n            scientificName: scientificName,\n            commonName: '',\n            assemblies: {default: ''}\n          };\n\n          Object.assign(ideo.organisms, augmentedOrganismMetadata);\n        });\n    } else {\n      promise = new Promise(function(resolve) {\n        var taxid = ideo.getTaxid(org);\n        augmentedOrganismMetadata[taxid] = ideo.organisms[taxid];\n        resolve();\n      });\n    }\n    getTaxidFromEutilsPromises.push(promise);\n  }\n\n  return Promise.all(getTaxidFromEutilsPromises).then(function() {\n    return augmentedOrganismMetadata;\n  });\n}\n\nfunction prepareTmpChrsAndTaxids(ideo) {\n  var orgs, taxids, tmpChrs, org, taxid, chrsOrgSlugs,\n    config = ideo.config;\n\n  taxids = [];\n  tmpChrs = {};\n  orgs = (config.multiorganism) ? config.organism : [config.organism];\n\n  return populateNonNativeOrg(orgs, ideo).then(function(orgMetadata) {\n    var orgFields = orgMetadata[taxid];\n\n    for (taxid in orgMetadata) {\n      orgFields = orgMetadata[taxid];\n      taxids.push(taxid);\n      if (config.multiorganism) {\n        if (typeof config.chromosomes !== 'undefined') {\n          chrsOrgSlugs = Object.keys(config.chromosomes).map(org => slug(org));\n          // Adjusts 'chromosomes' configuration parameter to make object\n          // keys use taxid instead of common organism name\n          if (chrsOrgSlugs.includes(slug(orgFields.scientificName))) {\n            org = orgFields.scientificName;\n          } else if (chrsOrgSlugs.includes(slug(orgFields.commonName))) {\n            org = orgFields.commonName;\n          }\n          if (slug(org) in config.chromosomes) {\n            tmpChrs[taxid] = config.chromosomes[slug(org)];\n          } else {\n            tmpChrs[taxid] = config.chromosomes[org.toLowerCase()];\n          }\n        } else {\n          tmpChrs = null;\n        }\n      }\n    }\n    return [tmpChrs, taxids];\n  });\n}\n\n/**\n * Sort taxids by the \"organism\" configuration option\n *\n * TODO: Handle taxid being passed as organism\n */\nfunction sortTaxidsByOriginalOrganismOption(ideo) {\n  var configOrganisms, sortedTaxids, i;\n  configOrganisms = ideo.config.organism;\n  sortedTaxids = [];\n  if (Array.isArray(configOrganisms)) {\n    // Handling multi-organism ideogram\n    for (i = 0; i < configOrganisms.length; i++) {\n      sortedTaxids.push(ideo.getTaxid(configOrganisms[i]));\n    }\n  } else {\n    // Handling single-organism ideogram\n    sortedTaxids.push(ideo.getTaxid(configOrganisms));\n  }\n  return sortedTaxids;\n}\n\nfunction getTaxidsForOrganismsInConfig(callback, ideo) {\n\n  prepareTmpChrsAndTaxids(ideo).then(function([tmpChrs, taxids]) {\n    var i, taxid, promise, assemblies, asmAccs,\n      config = ideo.config,\n      asmAndChrPromises = [];\n\n    for (i = 0; i < taxids.length; i++) {\n      taxid = taxids[i];\n      assemblies = ideo.organisms[taxid].assemblies;\n      asmAccs = Object.values(assemblies);\n      if (\n        assemblies.default === '' ||\n        ideo.assemblyIsAccession() && !asmAccs.includes(config.assembly)\n      ) {\n        promise = new Promise(function(resolve) {\n          setAssemblyAndChromosomes(taxid, resolve, ideo);\n        });\n      } else {\n        ideo.config.taxids = taxids;\n        if (ideo.config.multiorganism) {\n          ideo.config.chromosomes = tmpChrs;\n        }\n        promise = new Promise(function(resolve) {\n          resolve();\n        });\n      }\n\n      asmAndChrPromises.push(promise);\n    }\n\n    Promise.all(asmAndChrPromises).then(function() {\n      taxids = sortTaxidsByOriginalOrganismOption(ideo);\n      ideo.config.taxids = taxids;\n      return callback(taxids);\n    });\n  });\n}\n\nfunction getIsMultiorganism(taxidInit, ideo) {\n  return (\n    ('organism' in ideo.config && ideo.config.organism instanceof Array) ||\n    (taxidInit && ideo.config.taxid instanceof Array)\n  );\n}\n\n/**\n * Configure Ideogram taxids when 'organism' is not in ideo.config\n */\nfunction getTaxidsForOrganismsNotInConfig(taxidInit, callback, ideo) {\n  var taxids;\n\n  if (ideo.config.multiorganism) {\n    if (taxidInit) {\n      taxids = ideo.config.taxid;\n    }\n  } else {\n    if (taxidInit) {\n      taxids = [ideo.config.taxid];\n    }\n    ideo.config.taxids = taxids;\n  }\n  callback(taxids);\n}\n\n/**\n * Returns an array of taxids for the current ideogram\n * Also sets configuration parameters related to taxid(s), whether ideogram is\n * multiorganism, and adjusts chromosomes parameters as needed\n **/\nfunction getTaxids(callback) {\n  var taxidInit,\n    ideo = this;\n\n  taxidInit = 'taxid' in ideo.config;\n\n  ideo.config.multiorganism = getIsMultiorganism(taxidInit, ideo);\n\n  if (ideo.config.multiorganism) ideo.coordinateSystem = 'bp';\n\n  if ('organism' in ideo.config) {\n    getTaxidsForOrganismsInConfig(callback, ideo);\n  } else {\n    getTaxidsForOrganismsNotInConfig(taxidInit, callback, ideo);\n  }\n}\n\nexport {\n  getTaxids, getOrganismFromEutils\n};\n","import {d3} from '../lib';\nimport {\n  esearch, esummary, elink, getAssemblySearchUrl\n} from './eutils-config.js';\nimport {\n  getTaxids, getOrganismFromEutils\n} from './organisms.js';\n\n/**\n * Get a URL to ESearch the NCBI Nucleotide DB for an Assembly UID\n */\nfunction getESearchUrlForChromosomes(asmUid, ideo) {\n  var qs;\n\n  // Get a list of IDs for the chromosomes in this genome.\n  //\n  // Query chromosomes sequences in Nucleotide DB (nuccore) via\n  // Assembly DB E-Utils link.\n  qs = ('&db=nuccore&dbfrom=assembly&linkname=assembly_nuccore&' +\n    'cmd=neighbor_history&from_uid=' + asmUid);\n\n  return d3.json(ideo.elink + qs)\n    .then(function(data) {\n      var webenv = data.linksets[0].webenv;\n      qs =\n        '&db=nuccore' +\n        '&term=%231+AND+%28' +\n          'sequence_from_chromosome[Properties]+OR+' +\n          'sequence_from_plastid[Properties]+OR+' +\n          'sequence_from_mitochondrion[Properties]%29' +\n        '&WebEnv=' + webenv + '&usehistory=y&retmax=1000';\n      return ideo.esearch + qs;\n    });\n}\n\n/**\n * Request basic data on a list of chromosome IDs from ESearch\n */\nfunction fetchNucleotideSummary(data, ideo) {\n  var ids, ntSummary;\n  ids = data.esearchresult.idlist.join(',');\n  ntSummary = ideo.esummary + '&db=nucleotide&id=' + ids;\n  return d3.json(ntSummary);\n}\n\n/**\n * Get name and type for mitochondrial chromosome\n *\n * See example of \"MT\" in yeast:\n * https://eweitz.github.io/ideogram/eukaryotes?org=saccharomyces-cerevisiae\n */\nfunction parseMitochondrion(result, ideo) {\n  var type, cnIndex, chrName;\n\n  if (ideo.config.showNonNuclearChromosomes) {\n    type = result.genome;\n    cnIndex = result.subtype.split('|').indexOf('plasmid');\n    if (cnIndex === -1) {\n      chrName = 'MT';\n    } else {\n      // Seen in e.g. rice genome IRGSP-1.0 (GCF_001433935.1),\n      // From https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?retmode=json&db=nucleotide&id=996703432,996703431,996703430,996703429,996703428,996703427,996703426,996703425,996703424,996703423,996703422,996703421,194033210,11466763,7524755\n      // genome: 'mitochondrion',\n      // subtype: 'cell_line|plasmid',\n      // subname: 'A-58 CMS|B1',\n      chrName = result.subname.split('|')[cnIndex];\n    }\n  } else {\n    return [null, null];\n  }\n\n  return [chrName, type];\n}\n\n/**\n * Get name and type for chloroplastic chromosome.\n *\n * Plants have chloroplasts.  See e.g. green algae:\n * https://eweitz.github.io/ideogram/eukaryotes?org=micromonas-commoda\n */\nfunction parseChloroplastOrPlastid(ideo) {\n  // Plastid encountered with rice genome IRGSP-1.0 (GCF_001433935.1)\n  if (ideo.config.showNonNuclearChromosomes) {\n    return ['CP', 'chloroplast'];\n  }\n  return [null, null];\n}\n\n/**\n * Get name and type for apicoplast chromosome\n *\n * Plasmodium falciparum (malaria parasite) has such a chromosome, see e.g.:\n * https://eweitz.github.io/ideogram/eukaryotes?org=plasmodium-falciparum\n */\nfunction parseApicoplast(ideo) {\n  if (ideo.config.showNonNuclearChromosomes) {\n    return ['AP', 'apicoplast'];\n  }\n  return [null, null];\n}\n\n/**\n * Get name and type for nuclear chromosome\n *\n * These are typical chromosomes, like chromosome 1.\n */\nfunction parseNuclear(result) {\n  var type, cnIndex, chrName;\n\n  type = 'nuclear';\n  cnIndex = result.subtype.split('|').indexOf('chromosome');\n  chrName = result.subname.split('|')[cnIndex];\n\n  if (typeof chrName !== 'undefined' && chrName.substr(0, 3) === 'chr') {\n    // Convert \"chr12\" to \"12\", e.g. for banana (GCF_000313855.2)\n    chrName = chrName.substr(3);\n  }\n\n  return [chrName, type];\n}\n\n/**\n * Get name and type of any chromosome object from NCBI Nucleotide ESummary\n */\nfunction getChrNameAndType(result, ideo) {\n  var genome = result.genome;\n  if (genome === 'mitochondrion') {\n    return parseMitochondrion(result, ideo);\n  } else if (genome === 'chloroplast' || genome === 'plastid') {\n    return parseChloroplastOrPlastid(ideo);\n  } else if (genome === 'apicoplast') {\n    return parseApicoplast(ideo);\n  } else {\n    return parseNuclear(result);\n  }\n}\n\nfunction parseChromosome(result, ideo) {\n  var chrName, type, chromosome;\n\n  [chrName, type] = getChrNameAndType(result, ideo);\n\n  chromosome = {\n    name: chrName,\n    length: result.slen,\n    type: type\n  };\n\n  return chromosome;\n}\n\nfunction parseChromosomes(results, taxid, ideo) {\n  var x, chromosome, seenChrId, maxLength,\n    seenChrs = {},\n    chromosomes = [];\n\n  for (x in results) {\n    // omit list of result uids\n    if (x === 'uids') continue;\n\n    chromosome = parseChromosome(results[x], ideo);\n    seenChrId = chromosome.name + '_' + chromosome.length;\n    if (chromosome.type !== null && seenChrId in seenChrs === false) {\n      // seenChrs accounts for duplicate chromosomes seen with\n      // pig (Sus scrofa), likely GenBank and RefSeq copies.\n      chromosomes.push(chromosome);\n    }\n\n    seenChrs[seenChrId] = 1;\n  }\n\n  chromosomes = chromosomes.sort(Ideogram.sortChromosomes);\n\n  maxLength = {bp: 0, iscn: 0};\n  chromosomes.forEach(chr => {\n    if (chr.length > maxLength.bp) maxLength.bp = chr.length;\n  });\n  if (maxLength.bp > ideo.maxLength.bp) ideo.maxLength.bp = maxLength.bp;\n  ideo.maxLength[taxid] = maxLength;\n  ideo.coordinateSystem = 'bp';\n\n  return chromosomes;\n}\n\n/**\n * Request ESummary data from an ESearch on a genome assembly\n */\nfunction fetchAssemblySummary(data, ideo) {\n  var asmUid, asmSummaryUrl;\n\n  // NCBI Assembly database's internal identifier (uid) for this assembly\n  asmUid = data.esearchresult.idlist[0];\n  asmSummaryUrl = ideo.esummary + '&db=assembly&id=' + asmUid;\n\n  return d3.json(asmSummaryUrl);\n}\n\n/**\n * Returns assembly accession, as well as names and lengths of chromosomes for\n * an organism's best-known genome assembly, or for a specified assembly.\n *\n * Gets data from NCBI EUtils web API.\n *\n * @param callback Function to call upon completion of this async method\n */\nfunction getAssemblyAndChromosomesFromEutils(taxid, callback) {\n  var assemblyAccession,\n    ideo = this;\n\n  // Search for assembly, then\n  // get summary of that assembly, then\n  // get search URL for chromosomes in that assembly, then\n  // get search results containing chromosome IDs, then\n  // get summaries of each of those chromosome IDs, then\n  // format the chromosome summaries and pass them into callback function.\n  var asmSearchUrl = getAssemblySearchUrl(taxid, ideo);\n  d3.json(asmSearchUrl)\n    .then(function(data) {return fetchAssemblySummary(data, ideo);})\n    .then(function(data) {\n      var asmUid = data.result.uids[0];\n      assemblyAccession = data.result[asmUid];\n      return getESearchUrlForChromosomes(asmUid, ideo);\n    }).then(function(esearchUrl) {return d3.json(esearchUrl);})\n    .then(function(data) {return fetchNucleotideSummary(data, ideo);})\n    .then(function(data) {\n      var chromosomes = parseChromosomes(data.result, taxid, ideo);\n      return callback([assemblyAccession, chromosomes]);\n    }, function(rejectedReason) {\n      console.warn(rejectedReason);\n    });\n}\n\nexport {\n  esearch, esummary, elink, getOrganismFromEutils,\n  getTaxids, getAssemblyAndChromosomesFromEutils\n};\n","// The E-Utilies In Depth: Parameters, Syntax and More:\n// https://www.ncbi.nlm.nih.gov/books/NBK25499/\n\nvar apiKey = '&api_key=7e33ac6a08a6955ec3b83d214d22b21a2808';\n\nvar eutils = 'https://eutils.ncbi.nlm.nih.gov/entrez/eutils/';\nvar esearch = eutils + 'esearch.fcgi?retmode=json' + apiKey;\nvar esummary = eutils + 'esummary.fcgi?retmode=json' + apiKey;\nvar elink = eutils + 'elink.fcgi?retmode=json' + apiKey;\n\nfunction getAssemblySearchUrl(taxid, ideo) {\n  var termStem, asmSearchUrl;\n\n  if (ideo.assemblyIsAccession()) {\n    termStem = ideo.config.assembly + '%22[Assembly%20Accession]';\n  } else {\n    termStem = (\n      taxid + '%22[taxid]' +\n      'AND%20(%22latest%20refseq%22[filter])%20'\n    );\n  }\n\n  asmSearchUrl =\n    ideo.esearch +\n    '&db=assembly' +\n    '&term=%22' + termStem +\n    'AND%20(%22chromosome%20level%22[filter]%20' +\n    'OR%20%22complete%20genome%22[filter])';\n\n  return asmSearchUrl;\n}\n\nexport {esearch, esummary, elink, getAssemblySearchUrl};\n","/**\n * @fileoverview Methods to show (or hide) cytogenetic banding data\n */\n\nimport {d3} from '../lib';\n\nfunction hideUnshownBandLabels() {\n  var ideo = this;\n  var bandsToShow = ideo.bandsToShow.join(',');\n\n  // d3.selectAll resolves to querySelectorAll (QSA).\n  // QSA takes a surprisingly long time to complete,\n  // and scales with the number of selectors.\n  // Most bands are hidden, so we can optimize by\n  // Hiding all bands, then QSA'ing and displaying the\n  // relatively few bands that are shown.\n  d3.selectAll(ideo.selector + ' .bandLabel, .bandLabelStalk')\n    .style('display', 'none');\n  d3.selectAll(bandsToShow).style('display', '');\n}\n\nfunction getPrevRight(prevLabelXRight, prevHiddenBoxIndex, i,\n  textOffsets, chrModel) {\n  var prevTextBoxLeft, prevTextBoxWidth;\n\n  if (prevHiddenBoxIndex !== i) {\n    // This getBoundingClientRect() forces Chrome's\n    // 'Recalculate Style' and 'Layout', which takes 30-40 ms on Chrome.\n    // TODO: This forced synchronous layout would be nice to eliminate.\n    // prevTextBox = texts[i].getBoundingClientRect();\n    // prevLabelXRight = prevTextBox.left + prevTextBox.width;\n\n    // TODO: Account for number of characters in prevTextBoxWidth,\n    // maybe also zoom.\n    prevTextBoxLeft = textOffsets[chrModel.id][i];\n    prevTextBoxWidth = 36;\n\n    prevLabelXRight = prevTextBoxLeft + prevTextBoxWidth;\n  }\n\n  return prevLabelXRight;\n}\n\nfunction updateShown(indexesToShow, overlapRight, left, pad, prevRight, i,\n  isBefore) {\n  var hiddenIndex, doSkip,\n    thisRight = isBefore ? overlapRight : prevRight;\n\n  if (left < pad + thisRight) {\n    overlapRight = prevRight;\n    hiddenIndex = i;\n    doSkip = isBefore;\n  } else {\n    indexesToShow.push(i);\n  }\n\n  return [indexesToShow, overlapRight, hiddenIndex, doSkip];\n}\n\nfunction getIndexesToShow(offsets, chrModel) {\n  var i, hiddenIndex, left, prevRight, doSkip,\n    indexesToShow = [],\n    textsLength = offsets[chrModel.id].length,\n    overlapRight = 0, // Right X coordinate of overlapping label\n    pad = 5; // text padding\n\n  for (i = 0; i < textsLength; i++) {\n    // Ensures band labels don't overlap\n    left = offsets[chrModel.id][i];\n\n    [indexesToShow, overlapRight, hiddenIndex, doSkip] =\n      updateShown(indexesToShow, overlapRight, left, pad, prevRight, i, true);\n    if (doSkip) continue;\n\n    prevRight = getPrevRight(prevRight, hiddenIndex, i, offsets, chrModel);\n\n    [indexesToShow, overlapRight, hiddenIndex, doSkip] =\n      updateShown(indexesToShow, overlapRight, left, pad, prevRight, i, false);\n  }\n\n  return indexesToShow;\n}\n\n/**\n * Sets band labels to display on each chromosome, avoiding label overlap\n */\nfunction setBandsToShow(chrs, textOffsets) {\n  var index, i, j, indexesToShow, chrModel, selectorsToShow, ithLength,\n    ideo = this;\n\n  ideo.bandsToShow = [];\n\n  for (i = 0; i < chrs.length; i++) {\n\n    chrModel = chrs[i];\n\n    indexesToShow = getIndexesToShow(textOffsets, chrModel);\n\n    selectorsToShow = [];\n    ithLength = indexesToShow.length;\n\n    for (j = 0; j < ithLength; j++) {\n      index = indexesToShow[j];\n      selectorsToShow.push('#' + chrModel.id + ' .bsbsl-' + index);\n    }\n\n    ideo.bandsToShow = ideo.bandsToShow.concat(selectorsToShow);\n  }\n}\n\nexport {hideUnshownBandLabels, setBandsToShow};\n","/**\n * @fileoverview Methods to draw cytogenetic bands and their labels\n *\n */\n\nimport {d3} from '../lib';\nimport {hideUnshownBandLabels, setBandsToShow} from './show';\nimport {staticColors, staticGradients} from './styles';\nimport {configuredCss} from './../init/configure';\n\n/**\n * Draws text of cytoband label\n */\nfunction drawBandLabelText(chr, bandsToLabel, chrModel, textOffsets) {\n  var ideo = this,\n    layout = ideo._layout,\n    chrIndex = chrModel.chrIndex;\n\n  chr.selectAll('text')\n    .data(bandsToLabel)\n    .enter()\n    .append('g')\n    .attr('class', function(d, i) {\n      return 'bandLabel bsbsl-' + i;\n    })\n    .attr('transform', function(d) {\n      var transform = layout.getChromosomeBandLabelTranslate(d, chrIndex);\n\n      if (ideo.config.orientation === 'horizontal') {\n        textOffsets[chrModel.id].push(transform.x + 13);\n      } else {\n        textOffsets[chrModel.id].push(transform.y + 6);\n      }\n\n      return transform.translate;\n    })\n    .append('text')\n    .attr('text-anchor', layout.getChromosomeBandLabelAnchor(chrIndex))\n    .text(function(d) {return d.name;});\n\n  return textOffsets;\n}\n\n/**\n * Draws line between cytoband and its text label\n */\nfunction drawBandLabelStalk(chr, bandsToLabel, chrModel, textOffsets) {\n  var ideo = this;\n\n  chr.selectAll('line.bandLabelStalk')\n    .data(bandsToLabel)\n    .enter()\n    .append('g')\n    .attr('class', function(d, i) {\n      return 'bandLabelStalk bsbsl-' + i;\n    })\n    .attr('transform', function(d) {\n      var x, y;\n\n      x = ideo.round(d.px.start + d.px.width / 2);\n      y = -10;\n\n      textOffsets[chrModel.id].push(x + 13);\n\n      return 'translate(' + x + ',' + y + ')';\n    })\n    .append('line')\n    .attr('x1', 0)\n    .attr('y1', ideo._layout.getChromosomeBandTickY1(chrModel.chrIndex))\n    .attr('x2', 0)\n    .attr('y2', ideo._layout.getChromosomeBandTickY2(chrModel.chrIndex));\n}\n\nfunction getChrModels(chromosomes) {\n  var taxid, chr,\n    chrModels = [];\n\n  for (taxid in chromosomes) {\n    for (chr in chromosomes[taxid]) {\n      chrModels.push(chromosomes[taxid][chr]);\n    }\n  }\n\n  return chrModels;\n}\n\n/**\n * Draws text and stalks for cytogenetic band labels.\n *\n * Band labels are text like \"p11.11\".\n * Stalks are small lines that visually connect labels to their bands.\n */\nfunction drawBandLabels(chromosomes) {\n  var i, chr, chrModel, chrModels, bandsToLabel,\n    ideo = this,\n    textOffsets = {};\n\n  chrModels = getChrModels(chromosomes);\n\n  for (i = 0; i < chrModels.length; i++) {\n    chrModel = chrModels[i];\n    chr = d3.select(ideo.selector + ' #' + chrModel.id);\n    textOffsets[chrModel.id] = [];\n\n    // Don't show \"pter\" label for telocentric chromosomes, e.g. mouse\n    bandsToLabel = chrModel.bands.filter(d => d.name !== 'pter');\n\n    textOffsets =\n      ideo.drawBandLabelText(chr, bandsToLabel, chrModel, textOffsets);\n\n    ideo.drawBandLabelStalk(chr, bandsToLabel, chrModel, textOffsets);\n  }\n\n  ideo.setBandsToShow(chrModels, textOffsets);\n}\n\nfunction getStainAndColors(i, colors) {\n  var stain, color1, color2, color3;\n\n  stain = colors[i][0];\n  color1 = colors[i][1];\n  color2 = colors[i][2];\n  color3 = colors[i][3];\n\n  return [stain, color1, color2, color3];\n}\n\nfunction getGradients(colors) {\n  var i, stain, color1, color2, color3,\n    gradients = '';\n\n  for (i = 0; i < colors.length; i++) {\n    [stain, color1, color2, color3] = getStainAndColors(i, colors);\n    gradients +=\n      '<linearGradient id=\"' + stain + '\" x1=\"0%\" y1=\"0%\" x2=\"0%\" y2=\"100%\">';\n    if (stain === 'gneg') {\n      gradients +=\n        '<stop offset=\"70%\" stop-color=\"' + color2 + '\" />' +\n        '<stop offset=\"95%\" stop-color=\"' + color3 + '\" />' +\n        '<stop offset=\"100%\" stop-color=\"' + color1 + '\" />';\n    } else {\n      gradients +=\n        '<stop offset=\"5%\" stop-color=\"' + color1 + '\" />' +\n        '<stop offset=\"15%\" stop-color=\"' + color2 + '\" />' +\n        '<stop offset=\"60%\" stop-color=\"' + color3 + '\" />';\n    }\n    gradients +=\n      '</linearGradient>';\n  }\n\n  return gradients;\n}\n\n/**\n * Returns SVG gradients that give chromosomes a polished look\n */\nfunction getBandColorGradients() {\n  var css,\n    gradients = '';\n\n  gradients = getGradients(staticColors);\n\n  css = `<style>${configuredCss}</style>`;\n\n  gradients += staticGradients;\n  gradients = '<defs>' + gradients + '</defs>';\n  gradients = css + gradients;\n\n  return gradients;\n}\n\nexport {\n  drawBandLabels, getBandColorGradients, hideUnshownBandLabels, setBandsToShow,\n  drawBandLabelText, drawBandLabelStalk\n};\n","\nfunction getDelimiterTsvLinesAndInit(source, content) {\n  var delimiter, tsvLines, init;\n\n  if (typeof chrBands === 'undefined' && source !== 'native') {\n    delimiter = /\\t/;\n    tsvLines = content.split(/\\r\\n|\\n/);\n    init = 1;\n  } else {\n    delimiter = / /;\n    tsvLines = content;\n    init = 0;\n  }\n\n  return [delimiter, tsvLines, init];\n}\n\nfunction updateChromosomes(chromosomes) {\n  var tmp, i;\n\n  if (chromosomes instanceof Array && typeof chromosomes[0] === 'object') {\n    tmp = [];\n    for (i = 0; i < chromosomes.length; i++) {\n      tmp.push(chromosomes[i].name);\n    }\n    chromosomes = tmp;\n  }\n  return chromosomes;\n}\n\nfunction getLineObject(chr, columns, stain, taxid) {\n  return {\n    chr: chr,\n    bp: {\n      start: parseInt(columns[5], 10),\n      stop: parseInt(columns[6], 10)\n    },\n    iscn: {\n      start: parseInt(columns[3], 10),\n      stop: parseInt(columns[4], 10)\n    },\n    px: {\n      start: -1,\n      stop: -1,\n      width: -1\n    },\n    name: columns[1] + columns[2],\n    stain: stain,\n    taxid: taxid\n  };\n}\n\nfunction getStain(columns) {\n  var stain = columns[7];\n  // For e.g. acen and gvar, columns[8] (density) is undefined\n  if (columns[8]) stain += columns[8];\n  return stain;\n}\n\nfunction updateLines(lines, columns, taxid) {\n  var chr, stain, line;\n\n  chr = columns[0];\n  if (chr in lines === false) lines[chr] = [];\n\n  stain = getStain(columns);\n\n  line = getLineObject(chr, columns, stain, taxid);\n  lines[chr].push(line);\n\n  return lines;\n}\n\n/**\n * Reports if a cytogenetic band should be included in parse results\n *\n * TODO:\n * Normalize ideogram.chromosomes upstream.\n *\n * This function is complex because ideogram.chromosomes is (likely\n * unnecessarily) complex.  The \"ideogram.chromosomes\" object can\n * take many forms depending on the use case, and this results in\n * hard-to-reason-about functions like this.\n *\n * Normalizing ideogram.chromosomes to a common format somewhere upstream\n * would likely make this specific function and Ideogram in general much\n * more maintainable.\n */\nfunction shouldSkipBand(chrs, chr, taxid, ideo) {\n\n  var hasChrs, chrsAreList, chrNotInList, chrsAreObject,\n    innerChrsAreStrings, matchingChrObjs, chrNotInObject,\n    multiorganism = ideo.config.multiorganism;\n\n  hasChrs = typeof chrs !== 'undefined' && chrs !== null;\n  if (!hasChrs) return false;\n\n  chrsAreList = Array.isArray(chrs);\n  chrNotInList = chrsAreList && chrs.indexOf(chr) === -1;\n  chrsAreObject = typeof chrs === 'object';\n\n  if (chrsAreList && !chrsAreObject && chrNotInList) return true;\n\n  if (taxid in chrs === false && multiorganism) return false;\n\n  if (!multiorganism) {\n    // Encountered in single organism when showing subset of all chromosomes,\n    // e.g. only human X and Y as in https://eweitz.github.io/ideogram/homology-basic\n    matchingChrObjs = chrs.filter(thisChr => thisChr === chr);\n    chrNotInObject = matchingChrObjs.length === 0;\n  } else {\n    innerChrsAreStrings = typeof chrs[taxid][0] === 'string';\n    if (innerChrsAreStrings) {\n      chrNotInObject = chrs[taxid].includes(chr) === false;\n    } else {\n      matchingChrObjs = chrs[taxid].filter(thisChr => thisChr.name === chr);\n      chrNotInObject = matchingChrObjs.length === 0;\n    }\n  }\n  return chrNotInObject;\n\n}\n\n/**\n * Parses cytogenetic band data from a TSV file, or, if band data is\n * prefetched, from an array\n *\n * NCBI:\n * #chromosome arm band iscn_start iscn_stop bp_start bp_stop stain density\n * ftp://ftp.ncbi.nlm.nih.gov/pub/gdp/ideogram_9606_GCF_000001305.14_550_V1\n */\nfunction parseBands(taxid, chromosomes, ideo) {\n  var delimiter, tsvLines, columns, chr, i, init, source, content,\n    lines = {};\n\n  content = ideo.bandData[taxid];\n\n  if (Array.isArray(content)) source = 'native';\n\n  chromosomes = updateChromosomes(chromosomes);\n\n  // Destructure assignment fails oddly when transpiled.  2019-05-23\n  var result = getDelimiterTsvLinesAndInit(source, content);\n  delimiter = result[0];\n  tsvLines = result[1];\n  init = result[2];\n\n  for (i = init; i < tsvLines.length; i++) {\n    columns = tsvLines[i].split(delimiter);\n\n    chr = columns[0];\n    if (shouldSkipBand(chromosomes, chr, taxid, ideo)) {\n      // If specific chromosomes are configured, then skip processing all\n      // other fetched chromosomes.\n      continue;\n    }\n\n    lines = updateLines(lines, columns, taxid);\n  }\n\n  return lines;\n}\n\nexport {parseBands};\n","/**\n * @fileoverview Methods for processing chromosome length and banding data.\n *\n * Ideogram.js depicts chromosomes using data on their length, name, and\n * (if dealing with a very well-studied organism) cytogenetic banding data.\n * This file processes cytoband data that comes from biological research\n * institutions.\n *\n * For background on cytogenetic bands and how they are used in genomics, see:\n * https://ghr.nlm.nih.gov/primer/howgeneswork/genelocation\n *\n */\n\nimport {\n  drawBandLabels, getBandColorGradients, hideUnshownBandLabels, setBandsToShow,\n  drawBandLabelText, drawBandLabelStalk\n} from './draw';\nimport {parseBands} from './parse';\nimport {organismMetadata} from '../init/organism-metadata';\n\n/**\n * Gets bands array for given chromosomes, sets ideo.maxLength\n */\nfunction getBandsArray(chromosome, bandsByChr, taxid, ideo) {\n  var bands, chrLength,\n    bandsArray = [];\n\n  bands = bandsByChr[chromosome];\n  bandsArray.push(bands);\n\n  chrLength = {\n    iscn: bands[bands.length - 1].iscn.stop,\n    bp: bands[bands.length - 1].bp.stop\n  };\n\n  if (taxid in ideo.maxLength === false) {\n    ideo.maxLength[taxid] = {bp: 0, iscn: 0};\n  }\n\n  if (chrLength.iscn > ideo.maxLength[taxid].iscn) {\n    ideo.maxLength[taxid].iscn = chrLength.iscn;\n    if (chrLength.iscn > ideo.maxLength.iscn) {\n      ideo.maxLength.iscn = chrLength.iscn;\n    }\n  }\n\n  if (chrLength.bp > ideo.maxLength[taxid].bp) {\n    ideo.maxLength[taxid].bp = chrLength.bp;\n    if (chrLength.bp > ideo.maxLength.bp) {\n      ideo.maxLength.bp = chrLength.bp;\n    }\n  }\n\n  return bandsArray;\n}\n\n/**\n * Updates bandsArray, sets ideo.config.chromosomes and ideo.numChromosomes\n */\nfunction setChrsByTaxidsWithBands(taxid, chrs, bandsArray, ideo) {\n  var bandsByChr, chromosome, k, chrBandsArray;\n\n  bandsByChr = parseBands(taxid, chrs, ideo);\n\n  chrs = Object.keys(bandsByChr).sort(function(a, b) {\n    return a.localeCompare(b, 'en', {numeric: true});\n  });\n\n  if (\n    'chromosomes' in ideo.config === false ||\n    ideo.config.chromosomes === null\n  ) {\n    ideo.config.chromosomes = {};\n  }\n  if (chrs.length > 0) {\n    ideo.config.chromosomes[taxid] = chrs.slice();\n  }\n  ideo.numChromosomes += ideo.config.chromosomes[taxid].length;\n\n  for (k = 0; k < chrs.length; k++) {\n    chromosome = chrs[k];\n    chrBandsArray = getBandsArray(chromosome, bandsByChr, taxid, ideo);\n    bandsArray = bandsArray.concat(chrBandsArray);\n  }\n\n  return bandsArray;\n}\n\nfunction setChromosomesByTaxid(taxid, chrs, bandsArray, ideo) {\n  var chr, i;\n\n  if (\n    taxid in ideo.bandData ||\n    taxid in organismMetadata &&\n    ideo.assemblyIsAccession() === false\n  ) {\n    bandsArray = setChrsByTaxidsWithBands(taxid, chrs, bandsArray, ideo);\n  } else {\n    // If lacking band-level data\n    ideo.numChromosomes += chrs.length;\n\n    for (i = 0; i < chrs.length; i++) {\n      chr = chrs[i];\n      if (chr.length > ideo.maxLength.bp) ideo.maxLength.bp = chr.length;\n    }\n  }\n\n  return bandsArray;\n}\n\nfunction reportPerformance(t0, ideo) {\n  var t1 = new Date().getTime();\n  if (ideo.config.debug) {\n    console.log('Time in processBandData: ' + (t1 - t0) + ' ms');\n  }\n}\n\n/**\n * Completes default ideogram initialization by calling downstream functions\n * to process raw band data into full JSON objects, render chromosome and\n * cytoband figures and labels, apply initial graphical transformations,\n * hide overlapping band labels, and execute callbacks defined by client code\n */\nfunction processBandData(taxid) {\n  var bandsArray, chrs,\n    ideo = this,\n    config = ideo.config,\n    t0 = new Date().getTime();\n\n  bandsArray = [];\n\n  if ('chromosomes' in config) {\n    if (config.multiorganism) {\n      // Copy object\n      chrs = config.chromosomes;\n    } else if (taxid in config.chromosomes) {\n      // Copy array by value\n      chrs = config.chromosomes[taxid].slice();\n    } else {\n      // Copy array by value.  Needed for e.g. \"Homology, basic\"\n      chrs = config.chromosomes.slice();\n    }\n  }\n\n  bandsArray = setChromosomesByTaxid(taxid, chrs, bandsArray, ideo);\n\n  reportPerformance(t0, ideo);\n  return [taxid, bandsArray];\n}\n\nexport {\n  drawBandLabels, getBandColorGradients, processBandData,\n  setBandsToShow, hideUnshownBandLabels, drawBandLabelText, drawBandLabelStalk\n};\n","/**\n * @fileoverview Methods to create and handle a brush on a chromosome.\n *\n * Ideogram.js enables users to display a box around part of a chromosome\n * that represents a \"currently selected\" region.  The user can move this\n * box like a sliding window, e.g. by clicking and dragging the mouse.\n *\n * For background, see:\n * https://github.com/d3/d3-brush\n */\n\nimport {d3} from './lib';\n// See https://github.com/d3/d3/issues/2733\nimport {event as currentEvent} from 'd3-selection';\n\n/**\n * Custom event handler, fired upon dragging sliding window on chromosome\n */\nfunction onBrushMove() {\n  call(this.onBrushMoveCallback);\n}\n\nfunction setBrush(bpDomain, pxRange, xOffset, width, ideo) {\n  var xScale,\n    length = ideo.config.chrHeight;\n\n  xScale = d3.scaleLinear().domain(bpDomain).range(pxRange);\n\n  ideo.brush = d3.brushX()\n    .extent([[xOffset, 0], [length + xOffset, width]])\n    .on('brush', onBrushMove);\n\n  function onBrushMove() {\n    var extent = currentEvent.selection.map(xScale.invert),\n      from = Math.floor(extent[0]),\n      to = Math.ceil(extent[1]);\n\n    ideo.selectedRegion = {from: from, to: to, extent: (to - from)};\n\n    if (ideo.onBrushMove) {\n      ideo.onBrushMoveCallback();\n    }\n  }\n}\n\nfunction getBasePairDomainAndPixelRange(chrModel, xOffset) {\n  var band, i,\n    bpDomain = [1],\n    pxRange = [1],\n    lastBand = chrModel.bands.slice(-1)[0];\n\n  for (i = 0; i < chrModel.bands.length; i++) {\n    band = chrModel.bands[i];\n    bpDomain.push(band.bp.start);\n    pxRange.push(band.px.start + xOffset);\n  }\n\n  bpDomain.push(lastBand.bp.stop - 1);\n  pxRange.push(lastBand.px.stop + xOffset);\n\n  return [bpDomain, pxRange];\n}\n\n/**\n * Account for calls like createBrush('chr1:104325484-119977655')\n */\nfunction refineGenomicCoordinates(chr, from, to) {\n  var nameSplit, fromToSplit;\n\n  // Account for calls like createBrush('chr1:104325484-119977655')\n  nameSplit = chr.split(':');\n  fromToSplit = chr.split('-');\n  if (nameSplit.length > 1 && fromToSplit.length > 1) {\n    chr = nameSplit[0].replace('chr', '');\n    fromToSplit = nameSplit[1].split('-');\n    from = parseInt(fromToSplit[0]);\n    to = parseInt(fromToSplit[1] - 1);\n  }\n\n  return [chr, from, to];\n}\n\nfunction getChrModel(chr, ideo) {\n  var i, cm, chrModel;\n\n  for (i = 0; i < ideo.chromosomesArray.length; i++) {\n    cm = ideo.chromosomesArray[i];\n    if (cm.name === chr) {\n      chrModel = cm;\n      return chrModel;\n    }\n  }\n}\n\nfunction writeBrush(chrModel, from, to, xOffset, width, ideo) {\n  var x0, x1, yTranslate, yOffset;\n\n  x0 = ideo.convertBpToPx(chrModel, from) + xOffset;\n  x1 = ideo.convertBpToPx(chrModel, to) + xOffset;\n\n  yTranslate = ideo._layout.getChromosomeSetYTranslate(0);\n  yOffset = yTranslate + (ideo.config.chrWidth - width) / 2;\n\n  d3.select(ideo.selector).append('g')\n    .attr('class', 'brush')\n    .attr('transform', 'translate(0, ' + yOffset + ')')\n    .call(ideo.brush)\n    .call(ideo.brush.move, [x0, x1]);\n}\n\nfunction setSelectedRegion(from, to, ideo) {\n  // Genomics web UIs are 1-based, fully closed.\n  // I.e. If start = 20 bp and stop = 10 bp, then extent = 11 bp.\n  // Details:\n  // http://genome.ucsc.edu/blog/the-ucsc-genome-browser-coordinate-counting-systems/\n  // https://www.biostars.org/p/84686/\n  var extent = to - from + 1;\n  ideo.selectedRegion = {from: from, to: to, extent: extent};\n}\n\n/**\n * Creates a sliding window along a chromosome\n *\n * @param chr Chromosome name (e.g. 1) or range, e.g. chr1:104325484-119977655\n * @param from Genomic start coordinate in base pairs, e.g. 104325484\n * @param to Genomic end coordinate in base pairs, e.g. 119977655\n */\nfunction createBrush(chr, from, to) {\n  var chrModel, chrLengthBp, bpDomain, pxRange, lastBand,\n    ideo = this,\n    width = ideo.config.chrWidth + 6.5,\n    xOffset = ideo._layout.margin.left;\n\n  [chr, from, to] = refineGenomicCoordinates(chr, from, to);\n\n  chrModel = getChrModel(chr, ideo);\n\n  [bpDomain, pxRange] = getBasePairDomainAndPixelRange(chrModel, xOffset);\n\n  lastBand = chrModel.bands.slice(-1)[0];\n  chrLengthBp = lastBand.bp.stop;\n\n  if (typeof from === 'undefined') from = Math.floor(chrLengthBp / 10);\n  if (typeof to === 'undefined') to = Math.ceil(from * 2);\n\n  setBrush(bpDomain, pxRange, xOffset, width, ideo);\n\n  setSelectedRegion(from, to, ideo);\n  writeBrush(chrModel, from, to, xOffset, width, ideo);\n}\n\nexport {onBrushMove, createBrush};\n","/**\n * @fileoverview Allows a click event handler to be attached to the ideogram\n *\n * This works similar to the \"brush\" which allows a region to be selected.\n * The click handler does not allow a region, but a precise location.\n *\n */\n\nimport {d3} from './lib';\n// See https://github.com/d3/d3/issues/2733\nimport {event as currentEvent} from 'd3-selection';\n\n/**\n * Custom event handler, fired upon clicks on the chromosome (to change\n * position)\n */\nfunction onCursorMove() {\n  call(this.onCursorMoveCallback);\n}\n\nfunction setCursor(position, bpDomain, pxRange, xOffset, width, ideo) {\n  var xScale;\n\n  xScale = d3.scaleLinear().domain(bpDomain).range(pxRange);\n\n  if (!('rotatable' in ideo.config && ideo.config.rotatable === false)) {\n    console.warn('Using the cursor with rotate is not supported.');\n  }\n\n  var yTranslate = ideo._layout.getChromosomeSetYTranslate(0);\n  var yOffset = yTranslate + (ideo.config.chrWidth - width) / 2;\n\n  // TODO: check if newPosition is valid value (in range)\n\n  var cursorBrush = d3.select(ideo.selector).append('g')\n    .attr('class', 'brush')\n    .attr('transform', 'translate(0, ' + yOffset + ')')\n    .append('rect')\n    .attr('class', 'cursor')\n    .attr('x', xScale(position))\n    .attr('y', 0)\n    .attr('width', 1) // this could be a configuration param\n    .attr('height', 30); // MAGIC NUMBER! need help with this one\n\n  // call the callback for the first time (onLoad)\n  if (ideo.onCursorMove) {\n    ideo.onCursorMoveCallback(position);\n  }\n\n  if (!ideo.setCursorPosition) {\n    ideo.setCursorPosition = function(newPosition) {\n      // TODO: check if newPosition is valid value (in range)\n      cursorBrush.attr('x', xScale(newPosition));\n      if (ideo.onCursorMove) {\n        ideo.onCursorMoveCallback(newPosition);\n      }\n    };\n  }\n\n  d3.selectAll(ideo.selector + ' .chromosome').on('click', function() {\n    var x = currentEvent.offsetX; // minimum value seems to be 25\n\n    // adjust for screen (6 is a magic number that seems to work)\n    x -=6;\n\n    // move the cursor\n    cursorBrush.attr('x', x);\n\n    // calculate the new position and perform callback\n    var newPosition = Math.floor(xScale.invert(x));\n    if (ideo.onCursorMove) {\n      ideo.onCursorMoveCallback(newPosition);\n    }\n  });\n}\n\nfunction getBasePairDomainAndPixelRange(chrModel, xOffset) {\n  var band, i,\n    bpDomain = [1],\n    pxRange = [1],\n    lastBand = chrModel.bands.slice(-1)[0];\n\n  for (i = 0; i < chrModel.bands.length; i++) {\n    band = chrModel.bands[i];\n    bpDomain.push(band.bp.start);\n    pxRange.push(band.px.start + xOffset);\n  }\n\n  bpDomain.push(lastBand.bp.stop - 1);\n  pxRange.push(lastBand.px.stop + xOffset);\n\n  return [bpDomain, pxRange];\n}\n\nfunction getChrModel(chr, ideo) {\n  var i, cm, chrModel;\n\n  for (i = 0; i < ideo.chromosomesArray.length; i++) {\n    cm = ideo.chromosomesArray[i];\n    if (cm.name === chr) {\n      chrModel = cm;\n      return chrModel;\n    }\n  }\n}\n\n/**\n * Creates a clickable cursor along a chromosome.\n *\n * @param position Genomic start coordinate in base pairs, e.g. 104325484\n */\nfunction createClickCursor(position) {\n  var chrModel, bpDomain,\n    pxRange,\n    ideo = this,\n    width = ideo.config.chrWidth + 6.5, // 6.5 magic number?\n    xOffset = ideo._layout.margin.left;\n\n  if (typeof position === 'undefined') {\n    return false;\n  }\n\n  chrModel = getChrModel(ideo.config.chromosome, ideo);\n  [bpDomain, pxRange] = getBasePairDomainAndPixelRange(chrModel, xOffset);\n\n  // call setCursor to complete the job.\n  setCursor(position, bpDomain, pxRange, xOffset, width, ideo);\n}\n\nexport {onCursorMove, createClickCursor};\n","/**\n * @fileoverview Instance methods for sex chromosomes (allosomes).\n *\n * This module provides methods for drawing karyotypically normal\n * male and female mammalian genomes.\n */\n\n/**\n * Appends SVG elements depicting sex chromosomes to the document.\n */\nfunction drawSexChromosomes(container, chrIndex) {\n  var bandsArray, taxid, chrs,\n    sexChromosomeIndexes, sciLength,\n    chromosome, bands, chrModel, sci, homologIndex;\n\n  bandsArray = this.bandsArray;\n  taxid = this.config.taxid;\n  chrs = this.config.chromosomes[taxid];\n\n  if (this.config.sex === 'male') {\n    sexChromosomeIndexes = [1, 0];\n  } else {\n    sexChromosomeIndexes = [0, 0];\n  }\n\n  sciLength = sexChromosomeIndexes.length;\n\n  for (homologIndex = 0; homologIndex < sciLength; homologIndex++) {\n    sci = sexChromosomeIndexes[homologIndex] + chrIndex;\n    chromosome = chrs[sci];\n    bands = bandsArray[taxid][sci];\n    chrModel = this.getChromosomeModel(bands, chromosome, taxid, sci);\n    this.appendHomolog(chrModel, chrIndex, homologIndex, container);\n  }\n}\n\n/**\n * Sets instance properties regarding sex chromosomes.\n * Currently only supported for mammals.\n * TODO: Support all sexually reproducing taxa\n *   XY sex-determination (mammals):\n *     - Male: XY <- heterogametic\n *     - Female: XX\n *   ZW sex-determination (birds):\n *     - Male: ZZ\n *     - Female: ZW <- heterogametic\n *   X0 sex-determination (some insects):\n *     - Male: X0, i.e. only X <- heterogametic?\n *     - Female: XX\n * TODO: Support sex chromosome aneuploidies in mammals\n *     - Turner syndrome: X0\n *     - Klinefelter syndome: XXY\n *  More types:\n *  https://en.wikipedia.org/wiki/Category:Sex_chromosome_aneuploidies\n */\nfunction setSexChromosomes(chrs) {\n  var chr, i,\n    ideo = this,\n    sexChrs = {X: 1, Y: 1};\n\n  if (this.config.ploidy !== 2 || !this.config.sex) return;\n\n  ideo.sexChromosomes.list = [];\n\n  for (i = 0; i < chrs.length; i++) {\n    chr = chrs[i];\n    if (ideo.config.sex === 'male' && chr in sexChrs) {\n      ideo.sexChromosomes.list.push(chr);\n      if (!ideo.sexChromosomes.index) {\n        ideo.sexChromosomes.index = i;\n      }\n    } else if (chr === 'X') {\n      ideo.sexChromosomes.list.push(chr, chr);\n      ideo.sexChromosomes.index = i;\n    }\n  }\n}\n\nexport {drawSexChromosomes, setSexChromosomes};\n","/**\n * @fileoverview Methods to convert to and from different types of coordinates.\n *\n * Ideogram.js uses multiple coordinate systems, e.g. base pairs (bp) and\n * pixels (px).  These methods interconvert between those coordinate systems.\n *\n * TODO:\n * - Add methods to interconvert between ISCN coordinates and base pairs,\n * pixels.\n */\n\nfunction throwBpToPxError(bp, chr, band) {\n  throw new Error(\n    'Base pair out of range.  ' +\n    'bp: ' + bp + '; length of chr' + chr.name + ': ' + band.bp.stop\n  );\n}\n\nfunction getPx(chr, bp) {\n  var i, px, band, bpToIscnScale, iscn, iscnStart, iscnStop, iscnLength,\n    bpStart, bpStop, bpLength, pxStart, pxLength;\n\n  for (i = 0; i < chr.bands.length; i++) {\n    band = chr.bands[i];\n    bpStart = band.bp.start;\n    bpStop = band.bp.stop;\n    bpLength = bpStop - bpStart;\n    iscnStart = band.iscn.start;\n    iscnStop = band.iscn.stop;\n    iscnLength = iscnStop - iscnStart;\n    pxStart = band.px.start;\n    pxLength = band.px.width;\n\n    if (bp >= bpStart && bp <= bpStop) {\n      bpToIscnScale = iscnLength / bpLength;\n      iscn = iscnStart + (bp - bpStart) * bpToIscnScale;\n      px = pxStart + (pxLength * (iscn - iscnStart) / (iscnLength));\n\n      return [px, band];\n    }\n  }\n  return [null, band];\n}\n\n/**\n * Converts base pair coordinates to pixel offsets.\n * Bp-to-pixel scales differ among cytogenetic bands.\n *\n * For example, if we want to depict a gene on a chromosome, then we need\n * to convert the gene's location in base pairs to a location in pixels offset\n * from the start of the chromosome.\n */\nfunction convertBpToPx(chr, bp) {\n  var band, px;\n\n  if (chr.bands.length > 1) {\n    [px, band] = getPx(chr, bp);\n    if (px !== null) return px;\n  } else if (bp >= 1 && bp <= chr.length) {\n    px = chr.scale.bp * bp;\n    return px;\n  }\n\n  throwBpToPxError(bp, chr, band);\n}\n\nfunction throwPxToBpError(px, chr, pxStop) {\n  throw new Error(\n    'Pixel out of range.  ' +\n    'px: ' + px + '; length of chr' + chr.name + ': ' + pxStop\n  );\n}\n\nfunction getBp(iscnStop, iscnStart, px, pxStop, pxStart, band, iscnLength) {\n  var pxLength, bpLength, pxToIscnScale, iscn, bp;\n\n  iscnLength = iscnStop - iscnStart;\n  pxLength = pxStop - pxStart;\n  bpLength = band.bp.stop - band.bp.start;\n\n  pxToIscnScale = iscnLength / pxLength;\n  iscn = iscnStart + (px - pxStart) * pxToIscnScale;\n\n  bp = band.bp.start + (bpLength * (iscn - iscnStart) / iscnLength);\n\n  return Math.round(bp);\n}\n\n/**\n * Converts pixel offsets to base pair coordinates.\n * Pixel-to-bp scales differ among cytogenetic bands.\n *\n * For example, if we want to determine the genomic location a user clicked on\n * (e.g. when creating a brush / sliding window region), then we need to\n * convert pixels to base pairs.\n */\nfunction convertPxToBp(chr, px) {\n  var i, band, bp, pxStart, pxStop, iscnStart, iscnStop, iscnLength;\n\n  if (px === 0) {\n    px = chr.bands[0].px.start;\n  }\n\n  for (i = 0; i < chr.bands.length; i++) {\n    band = chr.bands[i];\n\n    pxStart = band.px.start;\n    pxStop = band.px.stop;\n    iscnStart = band.iscn.start;\n    iscnStop = band.iscn.stop;\n\n    if (px >= pxStart && px <= pxStop) {\n      bp = getBp(iscnStop, iscnStart, px, pxStop, pxStart, band, iscnLength);\n      return bp;\n    }\n  }\n  throwPxToBpError(px, chr, pxStop);\n}\n\nexport {convertBpToPx, convertPxToBp};\n","let array8 = arrayUntyped,\n    array16 = arrayUntyped,\n    array32 = arrayUntyped,\n    arrayLengthen = arrayLengthenUntyped,\n    arrayWiden = arrayWidenUntyped;\nif (typeof Uint8Array !== \"undefined\") {\n  array8 = function(n) { return new Uint8Array(n); };\n  array16 = function(n) { return new Uint16Array(n); };\n  array32 = function(n) { return new Uint32Array(n); };\n\n  arrayLengthen = function(array, length) {\n    if (array.length >= length) return array;\n    var copy = new array.constructor(length);\n    copy.set(array);\n    return copy;\n  };\n\n  arrayWiden = function(array, width) {\n    var copy;\n    switch (width) {\n      case 16: copy = array16(array.length); break;\n      case 32: copy = array32(array.length); break;\n      default: throw new Error(\"invalid array width!\");\n    }\n    copy.set(array);\n    return copy;\n  };\n}\n\nfunction arrayUntyped(n) {\n  var array = new Array(n), i = -1;\n  while (++i < n) array[i] = 0;\n  return array;\n}\n\nfunction arrayLengthenUntyped(array, length) {\n  var n = array.length;\n  while (n < length) array[n++] = 0;\n  return array;\n}\n\nfunction arrayWidenUntyped(array, width) {\n  if (width > 32) throw new Error(\"invalid array width!\");\n  return array;\n}\n\n// An arbitrarily-wide array of bitmasks\nfunction bitarray(n) {\n  this.length = n;\n  this.subarrays = 1;\n  this.width = 8;\n  this.masks = {\n    0: 0\n  }\n\n  this[0] = array8(n);\n}\n\nbitarray.prototype.lengthen = function(n) {\n  var i, len;\n  for (i = 0, len = this.subarrays; i < len; ++i) {\n    this[i] = arrayLengthen(this[i], n);\n  }\n  this.length = n;\n};\n\n// Reserve a new bit index in the array, returns {offset, one}\nbitarray.prototype.add = function() {\n  var m, w, one, i, len;\n\n  for (i = 0, len = this.subarrays; i < len; ++i) {\n    m = this.masks[i];\n    w = this.width - (32 * i);\n    // isolate the rightmost zero bit and return it as an unsigned int of 32 bits, if NaN or -1, return a 0 \n    one = (~m & (m + 1)) >>> 0;\n\n    if (w >= 32 && !one) {\n      continue;\n    }\n\n    if (w < 32 && (one & (1 << w))) {\n      // widen this subarray\n      this[i] = arrayWiden(this[i], w <<= 1);\n      this.width = 32 * i + w;\n    }\n\n    this.masks[i] |= one;\n\n    return {\n      offset: i,\n      one: one\n    };\n  }\n\n  // add a new subarray\n  this[this.subarrays] = array8(this.length);\n  this.masks[this.subarrays] = 1;\n  this.width += 8;\n  return {\n    offset: this.subarrays++,\n    one: 1\n  };\n};\n\n// Copy record from index src to index dest\nbitarray.prototype.copy = function(dest, src) {\n  var i, len;\n  for (i = 0, len = this.subarrays; i < len; ++i) {\n    this[i][dest] = this[i][src];\n  }\n};\n\n// Truncate the array to the given length\nbitarray.prototype.truncate = function(n) {\n  var i, len;\n  for (i = 0, len = this.subarrays; i < len; ++i) {\n    for (var j = this.length - 1; j >= n; j--) {\n      this[i][j] = 0;\n    }\n  }\n  this.length = n;\n};\n\n// Checks that all bits for the given index are 0\nbitarray.prototype.zero = function(n) {\n  var i, len;\n  for (i = 0, len = this.subarrays; i < len; ++i) {\n    if (this[i][n]) {\n      return false;\n    }\n  }\n  return true;\n};\n\n// Checks that all bits for the given index are 0 except for possibly one\nbitarray.prototype.zeroExcept = function(n, offset, zero) {\n  var i, len;\n  for (i = 0, len = this.subarrays; i < len; ++i) {\n    if (i === offset ? this[i][n] & zero : this[i][n]) {\n      return false;\n    }\n  }\n  return true;\n};\n\n// Checks that all bits for the given index are 0 except for the specified mask.\n// The mask should be an array of the same size as the filter subarrays width.\nbitarray.prototype.zeroExceptMask = function(n, mask) {\n  var i, len;\n  for (i = 0, len = this.subarrays; i < len; ++i) {\n    if (this[i][n] & mask[i]) {\n      return false;\n    }\n  }\n  return true;\n}\n\n// Checks that only the specified bit is set for the given index\nbitarray.prototype.only = function(n, offset, one) {\n  var i, len;\n  for (i = 0, len = this.subarrays; i < len; ++i) {\n    if (this[i][n] != (i === offset ? one : 0)) {\n      return false;\n    }\n  }\n  return true;\n};\n\n// Checks that only the specified bit is set for the given index except for possibly one other\nbitarray.prototype.onlyExcept = function(n, offset, zero, onlyOffset, onlyOne) {\n  var mask;\n  var i, len;\n  for (i = 0, len = this.subarrays; i < len; ++i) {\n    mask = this[i][n];\n    if (i === offset)\n      mask &= zero;\n    if (mask != (i === onlyOffset ? onlyOne : 0)) {\n      return false;\n    }\n  }\n  return true;\n};\n\nexport default {\n  array8: arrayUntyped,\n  array16: arrayUntyped,\n  array32: arrayUntyped,\n  arrayLengthen: arrayLengthenUntyped,\n  arrayWiden: arrayWidenUntyped,\n  bitarray: bitarray\n};\n","const filterExact = (bisect, value) => {\n  return function(values) {\n    var n = values.length;\n    return [bisect.left(values, value, 0, n), bisect.right(values, value, 0, n)];\n  };\n}\n\nconst filterRange = (bisect, range) => {\n  var min = range[0],\n      max = range[1];\n  return function(values) {\n    var n = values.length;\n    return [bisect.left(values, min, 0, n), bisect.left(values, max, 0, n)];\n  };\n}\n\nconst filterAll = values => {\n  return [0, values.length];\n}\n\nexport default {\n  filterExact,\n  filterRange,\n  filterAll\n};\n","export default d => {\n  return d;\n};\n","export default () =>  {\n  return null;\n}\n","export default () => {\n  return 0;\n}\n","import identity from './identity';\n\nfunction heap_by(f) {\n\n  // Builds a binary heap within the specified array a[lo:hi]. The heap has the\n  // property such that the parent a[lo+i] is always less than or equal to its\n  // two children: a[lo+2*i+1] and a[lo+2*i+2].\n  function heap(a, lo, hi) {\n    var n = hi - lo,\n        i = (n >>> 1) + 1;\n    while (--i > 0) sift(a, i, n, lo);\n    return a;\n  }\n\n  // Sorts the specified array a[lo:hi] in descending order, assuming it is\n  // already a heap.\n  function sort(a, lo, hi) {\n    var n = hi - lo,\n        t;\n    while (--n > 0) t = a[lo], a[lo] = a[lo + n], a[lo + n] = t, sift(a, 1, n, lo);\n    return a;\n  }\n\n  // Sifts the element a[lo+i-1] down the heap, where the heap is the contiguous\n  // slice of array a[lo:lo+n]. This method can also be used to update the heap\n  // incrementally, without incurring the full cost of reconstructing the heap.\n  function sift(a, i, n, lo) {\n    var d = a[--lo + i],\n        x = f(d),\n        child;\n    while ((child = i << 1) <= n) {\n      if (child < n && f(a[lo + child]) > f(a[lo + child + 1])) child++;\n      if (x <= f(a[lo + child])) break;\n      a[lo + i] = a[lo + child];\n      i = child;\n    }\n    a[lo + i] = d;\n  }\n\n  heap.sort = sort;\n  return heap;\n}\n\nconst h = heap_by(identity);\nh.by = heap_by;\n\nexport default h;\n","import identity from './identity';\nimport xFilterHeap from './heap';\n\nfunction heapselect_by(f) {\n  var heap = xFilterHeap.by(f);\n\n  // Returns a new array containing the top k elements in the array a[lo:hi].\n  // The returned array is not sorted, but maintains the heap property. If k is\n  // greater than hi - lo, then fewer than k elements will be returned. The\n  // order of elements in a is unchanged by this operation.\n  function heapselect(a, lo, hi, k) {\n    var queue = new Array(k = Math.min(hi - lo, k)),\n        min,\n        i,\n        d;\n\n    for (i = 0; i < k; ++i) queue[i] = a[lo++];\n    heap(queue, 0, k);\n\n    if (lo < hi) {\n      min = f(queue[0]);\n      do {\n        if (f(d = a[lo]) > min) {\n          queue[0] = d;\n          min = f(heap(queue, 0, k)[0]);\n        }\n      } while (++lo < hi);\n    }\n\n    return queue;\n  }\n\n  return heapselect;\n}\n\n\nconst h = heapselect_by(identity);\nh.by = heapselect_by; // assign the raw function to the export as well\n\nexport default h;\n","import identity from './identity';\n\nfunction bisect_by(f) {\n\n  // Locate the insertion point for x in a to maintain sorted order. The\n  // arguments lo and hi may be used to specify a subset of the array which\n  // should be considered; by default the entire array is used. If x is already\n  // present in a, the insertion point will be before (to the left of) any\n  // existing entries. The return value is suitable for use as the first\n  // argument to `array.splice` assuming that a is already sorted.\n  //\n  // The returned insertion point i partitions the array a into two halves so\n  // that all v < x for v in a[lo:i] for the left side and all v >= x for v in\n  // a[i:hi] for the right side.\n  function bisectLeft(a, x, lo, hi) {\n    while (lo < hi) {\n      var mid = lo + hi >>> 1;\n      if (f(a[mid]) < x) lo = mid + 1;\n      else hi = mid;\n    }\n    return lo;\n  }\n\n  // Similar to bisectLeft, but returns an insertion point which comes after (to\n  // the right of) any existing entries of x in a.\n  //\n  // The returned insertion point i partitions the array into two halves so that\n  // all v <= x for v in a[lo:i] for the left side and all v > x for v in\n  // a[i:hi] for the right side.\n  function bisectRight(a, x, lo, hi) {\n    while (lo < hi) {\n      var mid = lo + hi >>> 1;\n      if (x < f(a[mid])) hi = mid;\n      else lo = mid + 1;\n    }\n    return lo;\n  }\n\n  bisectRight.right = bisectRight;\n  bisectRight.left = bisectLeft;\n  return bisectRight;\n}\n\nconst bisect = bisect_by(identity);\nbisect.by = bisect_by; // assign the raw function to the export as well\n\nexport default bisect;\n\n","export default (array, index, deep) => {\n  for (var i = 0, n = index.length, copy = deep ? JSON.parse(JSON.stringify(array)) : new Array(n); i < n; ++i) {\n    copy[i] = array[index[i]];\n  }\n  return copy;\n}\n","const reduceIncrement = p => {\n  return p + 1;\n}\n\nconst reduceDecrement = p => {\n  return p - 1;\n}\n\nconst reduceAdd = f => {\n  return function(p, v) {\n    return p + +f(v);\n  };\n}\n\nconst reduceSubtract = f => {\n  return function(p, v) {\n    return p - f(v);\n  };\n}\n\nexport default {\n  reduceIncrement,\n  reduceDecrement,\n  reduceAdd,\n  reduceSubtract\n};\n","import deep from \"@ranfdev/deepobj\"\n// Note(cg): result was previsouly using lodash.result, not ESM compatible.\n \nconst get = (obj, prop) => {\n  const value = obj[prop];\n  return (typeof value === 'function') ? value.call(obj) : value;\n}\n\n/**\n * get value of object at a deep path.\n * if the resolved value is a function,\n * it's invoked with the `this` binding of \n * its parent object and its result is returned. \n *  \n * @param  {Object} obj  the object (e.g. { 'a': [{ 'b': { 'c1': 3, 'c2': 4} }], 'd': {e:1} }; )\n * @param  {String} path deep path (e.g. `d.e`` or `a[0].b.c1`. Dot notation (a.0.b)is also supported)\n * @return {Any}      the resolved value\n */\nconst reg = /\\[([\\w\\d]+)\\]/g;\nexport default (obj, path) => {\n  return deep(get, obj, path.replace(reg, '.$1'))\n}\n","export default function(t,e,i,n,r){for(r in n=(i=i.split(\".\")).splice(-1,1),i)e=e[i[r]]=e[i[r]]||{};return t(e,n)};\n//# sourceMappingURL=deepobj.m.js.map\n","import xfilterArray from './array';\nimport xfilterFilter from './filter';\nimport cr_identity from './identity';\nimport cr_null from './null';\nimport cr_zero from './zero';\nimport xfilterHeapselect from './heapselect';\nimport xfilterHeap from './heap';\nimport bisect from './bisect';\nimport permute from './permute';\nimport xfilterReduce from './reduce';\nimport result from './result';\n\n// constants\nvar REMOVED_INDEX = -1;\n\ncrossfilter.heap = xfilterHeap;\ncrossfilter.heapselect = xfilterHeapselect;\ncrossfilter.bisect = bisect;\ncrossfilter.permute = permute;\nexport default crossfilter;\n\nfunction crossfilter() {\n  var crossfilter = {\n    add: add,\n    remove: removeData,\n    dimension: dimension,\n    groupAll: groupAll,\n    size: size,\n    all: all,\n    allFiltered: allFiltered,\n    onChange: onChange,\n    isElementFiltered: isElementFiltered\n  };\n\n  var data = [], // the records\n      n = 0, // the number of records; data.length\n      filters, // 1 is filtered out\n      filterListeners = [], // when the filters change\n      dataListeners = [], // when data is added\n      removeDataListeners = [], // when data is removed\n      callbacks = [];\n\n  filters = new xfilterArray.bitarray(0);\n\n  // Adds the specified new records to this crossfilter.\n  function add(newData) {\n    var n0 = n,\n        n1 = newData.length;\n\n    // If there's actually new data to add…\n    // Merge the new data into the existing data.\n    // Lengthen the filter bitset to handle the new records.\n    // Notify listeners (dimensions and groups) that new data is available.\n    if (n1) {\n      data = data.concat(newData);\n      filters.lengthen(n += n1);\n      dataListeners.forEach(function(l) { l(newData, n0, n1); });\n      triggerOnChange('dataAdded');\n    }\n\n    return crossfilter;\n  }\n\n  // Removes all records that match the current filters, or if a predicate function is passed,\n  // removes all records matching the predicate (ignoring filters).\n  function removeData(predicate) {\n    var // Mapping from old record indexes to new indexes (after records removed)\n        newIndex = new Array(n),\n        removed = [],\n        usePred = typeof predicate === 'function',\n        shouldRemove = function (i) {\n          return usePred ? predicate(data[i], i) : filters.zero(i)\n        };\n\n    for (var index1 = 0, index2 = 0; index1 < n; ++index1) {\n      if ( shouldRemove(index1) ) {\n        removed.push(index1);\n        newIndex[index1] = REMOVED_INDEX;\n      } else {\n        newIndex[index1] = index2++;\n      }\n    }\n\n    // Remove all matching records from groups.\n    filterListeners.forEach(function(l) { l(-1, -1, [], removed, true); });\n\n    // Update indexes.\n    removeDataListeners.forEach(function(l) { l(newIndex); });\n\n    // Remove old filters and data by overwriting.\n    for (var index3 = 0, index4 = 0; index3 < n; ++index3) {\n      if ( newIndex[index3] !== REMOVED_INDEX ) {\n        if (index3 !== index4) filters.copy(index4, index3), data[index4] = data[index3];\n        ++index4;\n      }\n    }\n\n    data.length = n = index4;\n    filters.truncate(index4);\n    triggerOnChange('dataRemoved');\n  }\n\n  function maskForDimensions(dimensions) {\n    var n,\n        d,\n        len,\n        id,\n        mask = Array(filters.subarrays);\n    for (n = 0; n < filters.subarrays; n++) { mask[n] = ~0; }\n    for (d = 0, len = dimensions.length; d < len; d++) {\n      // The top bits of the ID are the subarray offset and the lower bits are the bit\n      // offset of the \"one\" mask.\n      id = dimensions[d].id();\n      mask[id >> 7] &= ~(0x1 << (id & 0x3f));\n    }\n    return mask;\n  }\n\n  // Return true if the data element at index i is filtered IN.\n  // Optionally, ignore the filters of any dimensions in the ignore_dimensions list.\n  function isElementFiltered(i, ignore_dimensions) {\n    var mask = maskForDimensions(ignore_dimensions || []);\n    return filters.zeroExceptMask(i,mask);\n  }\n\n  // Adds a new dimension with the specified value accessor function.\n  function dimension(value, iterable) {\n\n    if (typeof value === 'string') {\n      var accessorPath = value;\n      value = function(d) { return result(d, accessorPath); };\n    }\n\n    var dimension = {\n      filter: filter,\n      filterExact: filterExact,\n      filterRange: filterRange,\n      filterFunction: filterFunction,\n      filterAll: filterAll,\n      currentFilter: currentFilter,\n      hasCurrentFilter: hasCurrentFilter,\n      top: top,\n      bottom: bottom,\n      group: group,\n      groupAll: groupAll,\n      dispose: dispose,\n      remove: dispose, // for backwards-compatibility\n      accessor: value,\n      id: function() { return id; }\n    };\n\n    var one, // lowest unset bit as mask, e.g., 00001000\n        zero, // inverted one, e.g., 11110111\n        offset, // offset into the filters arrays\n        id, // unique ID for this dimension (reused when dimensions are disposed)\n        values, // sorted, cached array\n        index, // maps sorted value index -> record index (in data)\n        newValues, // temporary array storing newly-added values\n        newIndex, // temporary array storing newly-added index\n        iterablesIndexCount,\n        iterablesIndexFilterStatus,\n        iterablesEmptyRows = [],\n        sortRange = function(n) {\n          return cr_range(n).sort(function(A, B) {\n            var a = newValues[A], b = newValues[B];\n            return a < b ? -1 : a > b ? 1 : A - B;\n          });\n        },\n        refilter = xfilterFilter.filterAll, // for recomputing filter\n        refilterFunction, // the custom filter function in use\n        filterValue, // the value used for filtering (value, array, function or undefined)\n        filterValuePresent, // true if filterValue contains something\n        indexListeners = [], // when data is added\n        dimensionGroups = [],\n        lo0 = 0,\n        hi0 = 0,\n        t = 0,\n        k;\n\n    // Updating a dimension is a two-stage process. First, we must update the\n    // associated filters for the newly-added records. Once all dimensions have\n    // updated their filters, the groups are notified to update.\n    dataListeners.unshift(preAdd);\n    dataListeners.push(postAdd);\n\n    removeDataListeners.push(removeData);\n\n    // Add a new dimension in the filter bitmap and store the offset and bitmask.\n    var tmp = filters.add();\n    offset = tmp.offset;\n    one = tmp.one;\n    zero = ~one;\n\n    // Create a unique ID for the dimension\n    // IDs will be re-used if dimensions are disposed.\n    // For internal use the ID is the subarray offset shifted left 7 bits or'd with the\n    // bit offset of the set bit in the dimension's \"one\" mask.\n    id = (offset << 7) | (Math.log(one) / Math.log(2));\n\n    preAdd(data, 0, n);\n    postAdd(data, 0, n);\n\n    // Incorporates the specified new records into this dimension.\n    // This function is responsible for updating filters, values, and index.\n    function preAdd(newData, n0, n1) {\n      var newIterablesIndexCount,\n          newIterablesIndexFilterStatus;\n\n      if (iterable){\n        // Count all the values\n        t = 0;\n        j = 0;\n        k = [];\n\n        for (var i0 = 0; i0 < newData.length; i0++) {\n          for(j = 0, k = value(newData[i0]); j < k.length; j++) {\n            t++;\n          }\n        }\n\n        newValues = [];\n        newIterablesIndexCount = cr_range(newData.length);\n        newIterablesIndexFilterStatus = cr_index(t,1);\n        var unsortedIndex = cr_range(t);\n\n        for (var l = 0, index1 = 0; index1 < newData.length; index1++) {\n          k = value(newData[index1])\n          //\n          if(!k.length){\n            newIterablesIndexCount[index1] = 0;\n            iterablesEmptyRows.push(index1 + n0);\n            continue;\n          }\n          newIterablesIndexCount[index1] = k.length\n          for (j = 0; j < k.length; j++) {\n            newValues.push(k[j]);\n            unsortedIndex[l] = index1;\n            l++;\n          }\n        }\n\n        // Create the Sort map used to sort both the values and the valueToData indices\n        var sortMap = sortRange(t);\n\n        // Use the sortMap to sort the newValues\n        newValues = permute(newValues, sortMap);\n\n\n        // Use the sortMap to sort the unsortedIndex map\n        // newIndex should be a map of sortedValue -> crossfilterData\n        newIndex = permute(unsortedIndex, sortMap)\n\n      } else{\n        // Permute new values into natural order using a standard sorted index.\n        newValues = newData.map(value);\n        newIndex = sortRange(n1);\n        newValues = permute(newValues, newIndex);\n      }\n\n      // Bisect newValues to determine which new records are selected.\n      var bounds = refilter(newValues), lo1 = bounds[0], hi1 = bounds[1];\n\n      var index2, index3, index4;\n      if(iterable) {\n        n1 = t;\n        if (refilterFunction) {\n          for (index2 = 0; index2 < n1; ++index2) {\n            if (!refilterFunction(newValues[index2], index2)) {\n              if(--newIterablesIndexCount[newIndex[index2]] === 0) {\n                filters[offset][newIndex[index2] + n0] |= one;\n              }\n              newIterablesIndexFilterStatus[index2] = 1;\n            }\n          }\n        } else {\n          for (index3 = 0; index3 < lo1; ++index3) {\n            if(--newIterablesIndexCount[newIndex[index3]] === 0) {\n              filters[offset][newIndex[index3] + n0] |= one;\n            }\n            newIterablesIndexFilterStatus[index3] = 1;\n          }\n          for (index4 = hi1; index4 < n1; ++index4) {\n            if(--newIterablesIndexCount[newIndex[index4]] === 0) {\n              filters[offset][newIndex[index4] + n0] |= one;\n            }\n            newIterablesIndexFilterStatus[index4] = 1;\n          }\n        }\n      } else {\n        if (refilterFunction) {\n          for (index2 = 0; index2 < n1; ++index2) {\n            if (!refilterFunction(newValues[index2], index2)) {\n              filters[offset][newIndex[index2] + n0] |= one;\n            }\n          }\n        } else {\n          for (index3 = 0; index3 < lo1; ++index3) {\n            filters[offset][newIndex[index3] + n0] |= one;\n          }\n          for (index4 = hi1; index4 < n1; ++index4) {\n            filters[offset][newIndex[index4] + n0] |= one;\n          }\n        }\n      }\n\n      // If this dimension previously had no data, then we don't need to do the\n      // more expensive merge operation; use the new values and index as-is.\n      if (!n0) {\n        values = newValues;\n        index = newIndex;\n        iterablesIndexCount = newIterablesIndexCount;\n        iterablesIndexFilterStatus = newIterablesIndexFilterStatus;\n        lo0 = lo1;\n        hi0 = hi1;\n        return;\n      }\n\n\n\n      var oldValues = values,\n        oldIndex = index,\n        oldIterablesIndexFilterStatus = iterablesIndexFilterStatus,\n        old_n0,\n        i1 = 0;\n\n      i0 = 0;\n\n      if(iterable){\n        old_n0 = n0\n        n0 = oldValues.length;\n        n1 = t\n      }\n\n      // Otherwise, create new arrays into which to merge new and old.\n      values = iterable ? new Array(n0 + n1) : new Array(n);\n      index = iterable ? new Array(n0 + n1) : cr_index(n, n);\n      if(iterable) iterablesIndexFilterStatus = cr_index(n0 + n1, 1);\n\n      // Concatenate the newIterablesIndexCount onto the old one.\n      if(iterable) {\n        var oldiiclength = iterablesIndexCount.length;\n        iterablesIndexCount = xfilterArray.arrayLengthen(iterablesIndexCount, n);\n        for(var j=0; j+oldiiclength < n; j++) {\n          iterablesIndexCount[j+oldiiclength] = newIterablesIndexCount[j];\n        }\n      }\n\n      // Merge the old and new sorted values, and old and new index.\n      var index5 = 0;\n      for (; i0 < n0 && i1 < n1; ++index5) {\n        if (oldValues[i0] < newValues[i1]) {\n          values[index5] = oldValues[i0];\n          if(iterable) iterablesIndexFilterStatus[index5] = oldIterablesIndexFilterStatus[i0];\n          index[index5] = oldIndex[i0++];\n        } else {\n          values[index5] = newValues[i1];\n          if(iterable) iterablesIndexFilterStatus[index5] = newIterablesIndexFilterStatus[i1];\n          index[index5] = newIndex[i1++] + (iterable ? old_n0 : n0);\n        }\n      }\n\n      // Add any remaining old values.\n      for (; i0 < n0; ++i0, ++index5) {\n        values[index5] = oldValues[i0];\n        if(iterable) iterablesIndexFilterStatus[index5] = oldIterablesIndexFilterStatus[i0];\n        index[index5] = oldIndex[i0];\n      }\n\n      // Add any remaining new values.\n      for (; i1 < n1; ++i1, ++index5) {\n        values[index5] = newValues[i1];\n        if(iterable) iterablesIndexFilterStatus[index5] = newIterablesIndexFilterStatus[i1];\n        index[index5] = newIndex[i1] + (iterable ? old_n0 : n0);\n      }\n\n      // Bisect again to recompute lo0 and hi0.\n      bounds = refilter(values), lo0 = bounds[0], hi0 = bounds[1];\n    }\n\n    // When all filters have updated, notify index listeners of the new values.\n    function postAdd(newData, n0, n1) {\n      indexListeners.forEach(function(l) { l(newValues, newIndex, n0, n1); });\n      newValues = newIndex = null;\n    }\n\n    function removeData(reIndex) {\n      if (iterable) {\n        for (var i0 = 0, i1 = 0; i0 < iterablesEmptyRows.length; i0++) {\n          if (reIndex[iterablesEmptyRows[i0]] !== REMOVED_INDEX) {\n            iterablesEmptyRows[i1] = reIndex[iterablesEmptyRows[i0]];\n            i1++;\n          }\n        }\n        iterablesEmptyRows.length = i1;\n        for (i0 = 0, i1 = 0; i0 < n; i0++) {\n          if (reIndex[i0] !== REMOVED_INDEX) {\n            if (i1 !== i0) iterablesIndexCount[i1] = iterablesIndexCount[i0];\n            i1++;\n          }\n        }\n        iterablesIndexCount = iterablesIndexCount.slice(0, i1);\n      }\n      // Rewrite our index, overwriting removed values\n      var n0 = values.length;\n      for (var i = 0, j = 0, oldDataIndex; i < n0; ++i) {\n        oldDataIndex = index[i];\n        if (reIndex[oldDataIndex] !== REMOVED_INDEX) {\n          if (i !== j) values[j] = values[i];\n          index[j] = reIndex[oldDataIndex];\n          if (iterable) {\n            iterablesIndexFilterStatus[j] = iterablesIndexFilterStatus[i];\n          }\n          ++j;\n        }\n      }\n      values.length = j;\n      if (iterable) iterablesIndexFilterStatus = iterablesIndexFilterStatus.slice(0, j);\n      while (j < n0) index[j++] = 0;\n\n      // Bisect again to recompute lo0 and hi0.\n      var bounds = refilter(values);\n      lo0 = bounds[0], hi0 = bounds[1];\n    }\n\n    // Updates the selected values based on the specified bounds [lo, hi].\n    // This implementation is used by all the public filter methods.\n    function filterIndexBounds(bounds) {\n\n      var lo1 = bounds[0],\n          hi1 = bounds[1];\n\n      if (refilterFunction) {\n        refilterFunction = null;\n        filterIndexFunction(function(d, i) { return lo1 <= i && i < hi1; }, bounds[0] === 0 && bounds[1] === values.length);\n        lo0 = lo1;\n        hi0 = hi1;\n        return dimension;\n      }\n\n      var i,\n          j,\n          k,\n          added = [],\n          removed = [],\n          valueIndexAdded = [],\n          valueIndexRemoved = [];\n\n\n      // Fast incremental update based on previous lo index.\n      if (lo1 < lo0) {\n        for (i = lo1, j = Math.min(lo0, hi1); i < j; ++i) {\n          added.push(index[i]);\n          valueIndexAdded.push(i);\n        }\n      } else if (lo1 > lo0) {\n        for (i = lo0, j = Math.min(lo1, hi0); i < j; ++i) {\n          removed.push(index[i]);\n          valueIndexRemoved.push(i);\n        }\n      }\n\n      // Fast incremental update based on previous hi index.\n      if (hi1 > hi0) {\n        for (i = Math.max(lo1, hi0), j = hi1; i < j; ++i) {\n          added.push(index[i]);\n          valueIndexAdded.push(i);\n        }\n      } else if (hi1 < hi0) {\n        for (i = Math.max(lo0, hi1), j = hi0; i < j; ++i) {\n          removed.push(index[i]);\n          valueIndexRemoved.push(i);\n        }\n      }\n\n      if(!iterable) {\n        // Flip filters normally.\n\n        for(i=0; i<added.length; i++) {\n          filters[offset][added[i]] ^= one;\n        }\n\n        for(i=0; i<removed.length; i++) {\n          filters[offset][removed[i]] ^= one;\n        }\n\n      } else {\n        // For iterables, we need to figure out if the row has been completely removed vs partially included\n        // Only count a row as added if it is not already being aggregated. Only count a row\n        // as removed if the last element being aggregated is removed.\n\n        var newAdded = [];\n        var newRemoved = [];\n        for (i = 0; i < added.length; i++) {\n          iterablesIndexCount[added[i]]++\n          iterablesIndexFilterStatus[valueIndexAdded[i]] = 0;\n          if(iterablesIndexCount[added[i]] === 1) {\n            filters[offset][added[i]] ^= one;\n            newAdded.push(added[i]);\n          }\n        }\n        for (i = 0; i < removed.length; i++) {\n          iterablesIndexCount[removed[i]]--\n          iterablesIndexFilterStatus[valueIndexRemoved[i]] = 1;\n          if(iterablesIndexCount[removed[i]] === 0) {\n            filters[offset][removed[i]] ^= one;\n            newRemoved.push(removed[i]);\n          }\n        }\n\n        added = newAdded;\n        removed = newRemoved;\n\n        // Now handle empty rows.\n        if(refilter === xfilterFilter.filterAll) {\n          for(i = 0; i < iterablesEmptyRows.length; i++) {\n            if((filters[offset][k = iterablesEmptyRows[i]] & one)) {\n              // Was not in the filter, so set the filter and add\n              filters[offset][k] ^= one;\n              added.push(k);\n            }\n          }\n        } else {\n          // filter in place - remove empty rows if necessary\n          for(i = 0; i < iterablesEmptyRows.length; i++) {\n            if(!(filters[offset][k = iterablesEmptyRows[i]] & one)) {\n              // Was in the filter, so set the filter and remove\n              filters[offset][k] ^= one;\n              removed.push(k);\n            }\n          }\n        }\n      }\n\n      lo0 = lo1;\n      hi0 = hi1;\n      filterListeners.forEach(function(l) { l(one, offset, added, removed); });\n      triggerOnChange('filtered');\n      return dimension;\n    }\n\n    // Filters this dimension using the specified range, value, or null.\n    // If the range is null, this is equivalent to filterAll.\n    // If the range is an array, this is equivalent to filterRange.\n    // Otherwise, this is equivalent to filterExact.\n    function filter(range) {\n      return range == null\n          ? filterAll() : Array.isArray(range)\n          ? filterRange(range) : typeof range === \"function\"\n          ? filterFunction(range)\n          : filterExact(range);\n    }\n\n    // Filters this dimension to select the exact value.\n    function filterExact(value) {\n      filterValue = value;\n      filterValuePresent = true;\n      return filterIndexBounds((refilter = xfilterFilter.filterExact(bisect, value))(values));\n    }\n\n    // Filters this dimension to select the specified range [lo, hi].\n    // The lower bound is inclusive, and the upper bound is exclusive.\n    function filterRange(range) {\n      filterValue = range;\n      filterValuePresent = true;\n      return filterIndexBounds((refilter = xfilterFilter.filterRange(bisect, range))(values));\n    }\n\n    // Clears any filters on this dimension.\n    function filterAll() {\n      filterValue = undefined;\n      filterValuePresent = false;\n      return filterIndexBounds((refilter = xfilterFilter.filterAll)(values));\n    }\n\n    // Filters this dimension using an arbitrary function.\n    function filterFunction(f) {\n      filterValue = f;\n      filterValuePresent = true;\n      \n      refilterFunction = f;\n      refilter = xfilterFilter.filterAll;\n\n      filterIndexFunction(f, false);\n\n      var bounds = refilter(values);\n      lo0 = bounds[0], hi0 = bounds[1];\n\n      return dimension;\n    }\n\n    function filterIndexFunction(f, filterAll) {\n      var i,\n          k,\n          x,\n          added = [],\n          removed = [],\n          valueIndexAdded = [],\n          valueIndexRemoved = [],\n          indexLength = values.length;\n\n      if(!iterable) {\n        for (i = 0; i < indexLength; ++i) {\n          if (!(filters[offset][k = index[i]] & one) ^ !!(x = f(values[i], i))) {\n            if (x) added.push(k);\n            else removed.push(k);\n          }\n        }\n      }\n\n      if(iterable) {\n        for(i=0; i < indexLength; ++i) {\n          if(f(values[i], i)) {\n            added.push(index[i]);\n            valueIndexAdded.push(i);\n          } else {\n            removed.push(index[i]);\n            valueIndexRemoved.push(i);\n          }\n        }\n      }\n\n      if(!iterable) {\n        for(i=0; i<added.length; i++) {\n          if(filters[offset][added[i]] & one) filters[offset][added[i]] &= zero;\n        }\n\n        for(i=0; i<removed.length; i++) {\n          if(!(filters[offset][removed[i]] & one)) filters[offset][removed[i]] |= one;\n        }\n      } else {\n\n        var newAdded = [];\n        var newRemoved = [];\n        for (i = 0; i < added.length; i++) {\n          // First check this particular value needs to be added\n          if(iterablesIndexFilterStatus[valueIndexAdded[i]] === 1) {\n            iterablesIndexCount[added[i]]++\n            iterablesIndexFilterStatus[valueIndexAdded[i]] = 0;\n            if(iterablesIndexCount[added[i]] === 1) {\n              filters[offset][added[i]] ^= one;\n              newAdded.push(added[i]);\n            }\n          }\n        }\n        for (i = 0; i < removed.length; i++) {\n          // First check this particular value needs to be removed\n          if(iterablesIndexFilterStatus[valueIndexRemoved[i]] === 0) {\n            iterablesIndexCount[removed[i]]--\n            iterablesIndexFilterStatus[valueIndexRemoved[i]] = 1;\n            if(iterablesIndexCount[removed[i]] === 0) {\n              filters[offset][removed[i]] ^= one;\n              newRemoved.push(removed[i]);\n            }\n          }\n        }\n\n        added = newAdded;\n        removed = newRemoved;\n\n        // Now handle empty rows.\n        if(filterAll) {\n          for(i = 0; i < iterablesEmptyRows.length; i++) {\n            if((filters[offset][k = iterablesEmptyRows[i]] & one)) {\n              // Was not in the filter, so set the filter and add\n              filters[offset][k] ^= one;\n              added.push(k);\n            }\n          }\n        } else {\n          // filter in place - remove empty rows if necessary\n          for(i = 0; i < iterablesEmptyRows.length; i++) {\n            if(!(filters[offset][k = iterablesEmptyRows[i]] & one)) {\n              // Was in the filter, so set the filter and remove\n              filters[offset][k] ^= one;\n              removed.push(k);\n            }\n          }\n        }\n      }\n\n      filterListeners.forEach(function(l) { l(one, offset, added, removed); });\n      triggerOnChange('filtered');\n    }\n    \n    function currentFilter() {\n      return filterValue;\n    }\n    \n    function hasCurrentFilter() {\n      return filterValuePresent;\n    }\n\n    // Returns the top K selected records based on this dimension's order.\n    // Note: observes this dimension's filter, unlike group and groupAll.\n    function top(k, top_offset) {\n      var array = [],\n          i = hi0,\n          j,\n          toSkip = 0;\n\n      if(top_offset && top_offset > 0) toSkip = top_offset;\n\n      while (--i >= lo0 && k > 0) {\n        if (filters.zero(j = index[i])) {\n          if(toSkip > 0) {\n            //skip matching row\n            --toSkip;\n          } else {\n            array.push(data[j]);\n            --k;\n          }\n        }\n      }\n\n      if(iterable){\n        for(i = 0; i < iterablesEmptyRows.length && k > 0; i++) {\n          // Add row with empty iterable column at the end\n          if(filters.zero(j = iterablesEmptyRows[i])) {\n            if(toSkip > 0) {\n              //skip matching row\n              --toSkip;\n            } else {\n              array.push(data[j]);\n              --k;\n            }\n          }\n        }\n      }\n\n      return array;\n    }\n\n    // Returns the bottom K selected records based on this dimension's order.\n    // Note: observes this dimension's filter, unlike group and groupAll.\n    function bottom(k, bottom_offset) {\n      var array = [],\n          i,\n          j,\n          toSkip = 0;\n\n      if(bottom_offset && bottom_offset > 0) toSkip = bottom_offset;\n\n      if(iterable) {\n        // Add row with empty iterable column at the top\n        for(i = 0; i < iterablesEmptyRows.length && k > 0; i++) {\n          if(filters.zero(j = iterablesEmptyRows[i])) {\n            if(toSkip > 0) {\n              //skip matching row\n              --toSkip;\n            } else {\n              array.push(data[j]);\n              --k;\n            }\n          }\n        }\n      }\n\n      i = lo0;\n\n      while (i < hi0 && k > 0) {\n        if (filters.zero(j = index[i])) {\n          if(toSkip > 0) {\n            //skip matching row\n            --toSkip;\n          } else {\n            array.push(data[j]);\n            --k;\n          }\n        }\n        i++;\n      }\n\n      return array;\n    }\n\n    // Adds a new group to this dimension, using the specified key function.\n    function group(key) {\n      var group = {\n        top: top,\n        all: all,\n        reduce: reduce,\n        reduceCount: reduceCount,\n        reduceSum: reduceSum,\n        order: order,\n        orderNatural: orderNatural,\n        size: size,\n        dispose: dispose,\n        remove: dispose // for backwards-compatibility\n      };\n\n      // Ensure that this group will be removed when the dimension is removed.\n      dimensionGroups.push(group);\n\n      var groups, // array of {key, value}\n          groupIndex, // object id ↦ group id\n          groupWidth = 8,\n          groupCapacity = capacity(groupWidth),\n          k = 0, // cardinality\n          select,\n          heap,\n          reduceAdd,\n          reduceRemove,\n          reduceInitial,\n          update = cr_null,\n          reset = cr_null,\n          resetNeeded = true,\n          groupAll = key === cr_null,\n          n0old;\n\n      if (arguments.length < 1) key = cr_identity;\n\n      // The group listens to the crossfilter for when any dimension changes, so\n      // that it can update the associated reduce values. It must also listen to\n      // the parent dimension for when data is added, and compute new keys.\n      filterListeners.push(update);\n      indexListeners.push(add);\n      removeDataListeners.push(removeData);\n\n      // Incorporate any existing data into the grouping.\n      add(values, index, 0, n);\n\n      // Incorporates the specified new values into this group.\n      // This function is responsible for updating groups and groupIndex.\n      function add(newValues, newIndex, n0, n1) {\n\n        if(iterable) {\n          n0old = n0\n          n0 = values.length - newValues.length\n          n1 = newValues.length;\n        }\n\n        var oldGroups = groups,\n            reIndex = iterable ? [] : cr_index(k, groupCapacity),\n            add = reduceAdd,\n            remove = reduceRemove,\n            initial = reduceInitial,\n            k0 = k, // old cardinality\n            i0 = 0, // index of old group\n            i1 = 0, // index of new record\n            j, // object id\n            g0, // old group\n            x0, // old key\n            x1, // new key\n            g, // group to add\n            x; // key of group to add\n\n        // If a reset is needed, we don't need to update the reduce values.\n        if (resetNeeded) add = initial = cr_null;\n        if (resetNeeded) remove = initial = cr_null;\n\n        // Reset the new groups (k is a lower bound).\n        // Also, make sure that groupIndex exists and is long enough.\n        groups = new Array(k), k = 0;\n        if(iterable){\n          groupIndex = k0 ? groupIndex : [];\n        }\n        else{\n          groupIndex = k0 > 1 ? xfilterArray.arrayLengthen(groupIndex, n) : cr_index(n, groupCapacity);\n        }\n\n\n        // Get the first old key (x0 of g0), if it exists.\n        if (k0) x0 = (g0 = oldGroups[0]).key;\n\n        // Find the first new key (x1), skipping NaN keys.\n        while (i1 < n1 && !((x1 = key(newValues[i1])) >= x1)) ++i1;\n\n        // While new keys remain…\n        while (i1 < n1) {\n\n          // Determine the lesser of the two current keys; new and old.\n          // If there are no old keys remaining, then always add the new key.\n          if (g0 && x0 <= x1) {\n            g = g0, x = x0;\n\n            // Record the new index of the old group.\n            reIndex[i0] = k;\n\n            // Retrieve the next old key.\n            g0 = oldGroups[++i0];\n            if (g0) x0 = g0.key;\n          } else {\n            g = {key: x1, value: initial()}, x = x1;\n          }\n\n          // Add the lesser group.\n          groups[k] = g;\n\n          // Add any selected records belonging to the added group, while\n          // advancing the new key and populating the associated group index.\n\n          while (x1 <= x) {\n            j = newIndex[i1] + (iterable ? n0old : n0)\n\n\n            if(iterable){\n              if(groupIndex[j]){\n                groupIndex[j].push(k)\n              }\n              else{\n                groupIndex[j] = [k]\n              }\n            }\n            else{\n              groupIndex[j] = k;\n            }\n\n            // Always add new values to groups. Only remove when not in filter.\n            // This gives groups full information on data life-cycle.\n            g.value = add(g.value, data[j], true);\n            if (!filters.zeroExcept(j, offset, zero)) g.value = remove(g.value, data[j], false);\n            if (++i1 >= n1) break;\n            x1 = key(newValues[i1]);\n          }\n\n          groupIncrement();\n        }\n\n        // Add any remaining old groups that were greater th1an all new keys.\n        // No incremental reduce is needed; these groups have no new records.\n        // Also record the new index of the old group.\n        while (i0 < k0) {\n          groups[reIndex[i0] = k] = oldGroups[i0++];\n          groupIncrement();\n        }\n\n\n        // Fill in gaps with empty arrays where there may have been rows with empty iterables\n        if(iterable){\n          for (var index1 = 0; index1 < n; index1++) {\n            if(!groupIndex[index1]){\n              groupIndex[index1] = [];\n            }\n          }\n        }\n\n        // If we added any new groups before any old groups,\n        // update the group index of all the old records.\n        if(k > i0){\n          if(iterable){\n            for (i0 = 0; i0 < n0old; ++i0) {\n              for (index1 = 0; index1 < groupIndex[i0].length; index1++) {\n                groupIndex[i0][index1] = reIndex[groupIndex[i0][index1]];\n              }\n            }\n          }\n          else{\n            for (i0 = 0; i0 < n0; ++i0) {\n              groupIndex[i0] = reIndex[groupIndex[i0]];\n            }\n          }\n        }\n\n        // Modify the update and reset behavior based on the cardinality.\n        // If the cardinality is less than or equal to one, then the groupIndex\n        // is not needed. If the cardinality is zero, then there are no records\n        // and therefore no groups to update or reset. Note that we also must\n        // change the registered listener to point to the new method.\n        j = filterListeners.indexOf(update);\n        if (k > 1 || iterable) {\n          update = updateMany;\n          reset = resetMany;\n        } else {\n          if (!k && groupAll) {\n            k = 1;\n            groups = [{key: null, value: initial()}];\n          }\n          if (k === 1) {\n            update = updateOne;\n            reset = resetOne;\n          } else {\n            update = cr_null;\n            reset = cr_null;\n          }\n          groupIndex = null;\n        }\n        filterListeners[j] = update;\n\n        // Count the number of added groups,\n        // and widen the group index as needed.\n        function groupIncrement() {\n          if(iterable){\n            k++\n            return\n          }\n          if (++k === groupCapacity) {\n            reIndex = xfilterArray.arrayWiden(reIndex, groupWidth <<= 1);\n            groupIndex = xfilterArray.arrayWiden(groupIndex, groupWidth);\n            groupCapacity = capacity(groupWidth);\n          }\n        }\n      }\n\n      function removeData(reIndex) {\n        if (k > 1 || iterable) {\n          var oldK = k,\n              oldGroups = groups,\n              seenGroups = cr_index(oldK, oldK),\n              i,\n              i0,\n              j;\n\n          // Filter out non-matches by copying matching group index entries to\n          // the beginning of the array.\n          if (!iterable) {\n            for (i = 0, j = 0; i < n; ++i) {\n              if (reIndex[i] !== REMOVED_INDEX) {\n                seenGroups[groupIndex[j] = groupIndex[i]] = 1;\n                ++j;\n              }\n            }\n          } else {\n            for (i = 0, j = 0; i < n; ++i) {\n              if (reIndex[i] !== REMOVED_INDEX) {\n                groupIndex[j] = groupIndex[i];\n                for (i0 = 0; i0 < groupIndex[j].length; i0++) {\n                  seenGroups[groupIndex[j][i0]] = 1;\n                }\n                ++j;\n              }\n            }\n          }\n\n          // Reassemble groups including only those groups that were referred\n          // to by matching group index entries.  Note the new group index in\n          // seenGroups.\n          groups = [], k = 0;\n          for (i = 0; i < oldK; ++i) {\n            if (seenGroups[i]) {\n              seenGroups[i] = k++;\n              groups.push(oldGroups[i]);\n            }\n          }\n\n          if (k > 1 || iterable) {\n            // Reindex the group index using seenGroups to find the new index.\n            if (!iterable) {\n              for (i = 0; i < j; ++i) groupIndex[i] = seenGroups[groupIndex[i]];\n            } else {\n              for (i = 0; i < j; ++i) {\n                for (i0 = 0; i0 < groupIndex[i].length; ++i0) {\n                  groupIndex[i][i0] = seenGroups[groupIndex[i][i0]];\n                }\n              }\n            }\n          } else {\n            groupIndex = null;\n          }\n          filterListeners[filterListeners.indexOf(update)] = k > 1 || iterable\n              ? (reset = resetMany, update = updateMany)\n              : k === 1 ? (reset = resetOne, update = updateOne)\n              : reset = update = cr_null;\n        } else if (k === 1) {\n          if (groupAll) return;\n          for (var index3 = 0; index3 < n; ++index3) if (reIndex[index3] !== REMOVED_INDEX) return;\n          groups = [], k = 0;\n          filterListeners[filterListeners.indexOf(update)] =\n          update = reset = cr_null;\n        }\n      }\n\n      // Reduces the specified selected or deselected records.\n      // This function is only used when the cardinality is greater than 1.\n      // notFilter indicates a crossfilter.add/remove operation.\n      function updateMany(filterOne, filterOffset, added, removed, notFilter) {\n\n        if ((filterOne === one && filterOffset === offset) || resetNeeded) return;\n\n        var i,\n            j,\n            k,\n            n,\n            g;\n\n        if(iterable){\n          // Add the added values.\n          for (i = 0, n = added.length; i < n; ++i) {\n            if (filters.zeroExcept(k = added[i], offset, zero)) {\n              for (j = 0; j < groupIndex[k].length; j++) {\n                g = groups[groupIndex[k][j]];\n                g.value = reduceAdd(g.value, data[k], false, j);\n              }\n            }\n          }\n\n          // Remove the removed values.\n          for (i = 0, n = removed.length; i < n; ++i) {\n            if (filters.onlyExcept(k = removed[i], offset, zero, filterOffset, filterOne)) {\n              for (j = 0; j < groupIndex[k].length; j++) {\n                g = groups[groupIndex[k][j]];\n                g.value = reduceRemove(g.value, data[k], notFilter, j);\n              }\n            }\n          }\n          return;\n        }\n\n        // Add the added values.\n        for (i = 0, n = added.length; i < n; ++i) {\n          if (filters.zeroExcept(k = added[i], offset, zero)) {\n            g = groups[groupIndex[k]];\n            g.value = reduceAdd(g.value, data[k], false);\n          }\n        }\n\n        // Remove the removed values.\n        for (i = 0, n = removed.length; i < n; ++i) {\n          if (filters.onlyExcept(k = removed[i], offset, zero, filterOffset, filterOne)) {\n            g = groups[groupIndex[k]];\n            g.value = reduceRemove(g.value, data[k], notFilter);\n          }\n        }\n      }\n\n      // Reduces the specified selected or deselected records.\n      // This function is only used when the cardinality is 1.\n      // notFilter indicates a crossfilter.add/remove operation.\n      function updateOne(filterOne, filterOffset, added, removed, notFilter) {\n        if ((filterOne === one && filterOffset === offset) || resetNeeded) return;\n\n        var i,\n            k,\n            n,\n            g = groups[0];\n\n        // Add the added values.\n        for (i = 0, n = added.length; i < n; ++i) {\n          if (filters.zeroExcept(k = added[i], offset, zero)) {\n            g.value = reduceAdd(g.value, data[k], false);\n          }\n        }\n\n        // Remove the removed values.\n        for (i = 0, n = removed.length; i < n; ++i) {\n          if (filters.onlyExcept(k = removed[i], offset, zero, filterOffset, filterOne)) {\n            g.value = reduceRemove(g.value, data[k], notFilter);\n          }\n        }\n      }\n\n      // Recomputes the group reduce values from scratch.\n      // This function is only used when the cardinality is greater than 1.\n      function resetMany() {\n        var i,\n            j,\n            g;\n\n        // Reset all group values.\n        for (i = 0; i < k; ++i) {\n          groups[i].value = reduceInitial();\n        }\n\n        // We add all records and then remove filtered records so that reducers\n        // can build an 'unfiltered' view even if there are already filters in\n        // place on other dimensions.\n        if(iterable){\n          for (i = 0; i < n; ++i) {\n            for (j = 0; j < groupIndex[i].length; j++) {\n              g = groups[groupIndex[i][j]];\n              g.value = reduceAdd(g.value, data[i], true, j);\n            }\n          }\n          for (i = 0; i < n; ++i) {\n            if (!filters.zeroExcept(i, offset, zero)) {\n              for (j = 0; j < groupIndex[i].length; j++) {\n                g = groups[groupIndex[i][j]];\n                g.value = reduceRemove(g.value, data[i], false, j);\n              }\n            }\n          }\n          return;\n        }\n\n        for (i = 0; i < n; ++i) {\n          g = groups[groupIndex[i]];\n          g.value = reduceAdd(g.value, data[i], true);\n        }\n        for (i = 0; i < n; ++i) {\n          if (!filters.zeroExcept(i, offset, zero)) {\n            g = groups[groupIndex[i]];\n            g.value = reduceRemove(g.value, data[i], false);\n          }\n        }\n      }\n\n      // Recomputes the group reduce values from scratch.\n      // This function is only used when the cardinality is 1.\n      function resetOne() {\n        var i,\n            g = groups[0];\n\n        // Reset the singleton group values.\n        g.value = reduceInitial();\n\n        // We add all records and then remove filtered records so that reducers\n        // can build an 'unfiltered' view even if there are already filters in\n        // place on other dimensions.\n        for (i = 0; i < n; ++i) {\n          g.value = reduceAdd(g.value, data[i], true);\n        }\n\n        for (i = 0; i < n; ++i) {\n          if (!filters.zeroExcept(i, offset, zero)) {\n            g.value = reduceRemove(g.value, data[i], false);\n          }\n        }\n      }\n\n      // Returns the array of group values, in the dimension's natural order.\n      function all() {\n        if (resetNeeded) reset(), resetNeeded = false;\n        return groups;\n      }\n\n      // Returns a new array containing the top K group values, in reduce order.\n      function top(k) {\n        var top = select(all(), 0, groups.length, k);\n        return heap.sort(top, 0, top.length);\n      }\n\n      // Sets the reduce behavior for this group to use the specified functions.\n      // This method lazily recomputes the reduce values, waiting until needed.\n      function reduce(add, remove, initial) {\n        reduceAdd = add;\n        reduceRemove = remove;\n        reduceInitial = initial;\n        resetNeeded = true;\n        return group;\n      }\n\n      // A convenience method for reducing by count.\n      function reduceCount() {\n        return reduce(xfilterReduce.reduceIncrement, xfilterReduce.reduceDecrement, cr_zero);\n      }\n\n      // A convenience method for reducing by sum(value).\n      function reduceSum(value) {\n        return reduce(xfilterReduce.reduceAdd(value), xfilterReduce.reduceSubtract(value), cr_zero);\n      }\n\n      // Sets the reduce order, using the specified accessor.\n      function order(value) {\n        select = xfilterHeapselect.by(valueOf);\n        heap = xfilterHeap.by(valueOf);\n        function valueOf(d) { return value(d.value); }\n        return group;\n      }\n\n      // A convenience method for natural ordering by reduce value.\n      function orderNatural() {\n        return order(cr_identity);\n      }\n\n      // Returns the cardinality of this group, irrespective of any filters.\n      function size() {\n        return k;\n      }\n\n      // Removes this group and associated event listeners.\n      function dispose() {\n        var i = filterListeners.indexOf(update);\n        if (i >= 0) filterListeners.splice(i, 1);\n        i = indexListeners.indexOf(add);\n        if (i >= 0) indexListeners.splice(i, 1);\n        i = removeDataListeners.indexOf(removeData);\n        if (i >= 0) removeDataListeners.splice(i, 1);\n        i = dimensionGroups.indexOf(group);\n        if (i >= 0) dimensionGroups.splice(i, 1);\n        return group;\n      }\n\n      return reduceCount().orderNatural();\n    }\n\n    // A convenience function for generating a singleton group.\n    function groupAll() {\n      var g = group(cr_null), all = g.all;\n      delete g.all;\n      delete g.top;\n      delete g.order;\n      delete g.orderNatural;\n      delete g.size;\n      g.value = function() { return all()[0].value; };\n      return g;\n    }\n\n    // Removes this dimension and associated groups and event listeners.\n    function dispose() {\n      dimensionGroups.forEach(function(group) { group.dispose(); });\n      var i = dataListeners.indexOf(preAdd);\n      if (i >= 0) dataListeners.splice(i, 1);\n      i = dataListeners.indexOf(postAdd);\n      if (i >= 0) dataListeners.splice(i, 1);\n      i = removeDataListeners.indexOf(removeData);\n      if (i >= 0) removeDataListeners.splice(i, 1);\n      filters.masks[offset] &= zero;\n      return filterAll();\n    }\n\n    return dimension;\n  }\n\n  // A convenience method for groupAll on a dummy dimension.\n  // This implementation can be optimized since it always has cardinality 1.\n  function groupAll() {\n    var group = {\n      reduce: reduce,\n      reduceCount: reduceCount,\n      reduceSum: reduceSum,\n      value: value,\n      dispose: dispose,\n      remove: dispose // for backwards-compatibility\n    };\n\n    var reduceValue,\n        reduceAdd,\n        reduceRemove,\n        reduceInitial,\n        resetNeeded = true;\n\n    // The group listens to the crossfilter for when any dimension changes, so\n    // that it can update the reduce value. It must also listen to the parent\n    // dimension for when data is added.\n    filterListeners.push(update);\n    dataListeners.push(add);\n\n    // For consistency; actually a no-op since resetNeeded is true.\n    add(data, 0, n);\n\n    // Incorporates the specified new values into this group.\n    function add(newData, n0) {\n      var i;\n\n      if (resetNeeded) return;\n\n      // Cycle through all the values.\n      for (i = n0; i < n; ++i) {\n\n        // Add all values all the time.\n        reduceValue = reduceAdd(reduceValue, data[i], true);\n\n        // Remove the value if filtered.\n        if (!filters.zero(i)) {\n          reduceValue = reduceRemove(reduceValue, data[i], false);\n        }\n      }\n    }\n\n    // Reduces the specified selected or deselected records.\n    function update(filterOne, filterOffset, added, removed, notFilter) {\n      var i,\n          k,\n          n;\n\n      if (resetNeeded) return;\n\n      // Add the added values.\n      for (i = 0, n = added.length; i < n; ++i) {\n        if (filters.zero(k = added[i])) {\n          reduceValue = reduceAdd(reduceValue, data[k], notFilter);\n        }\n      }\n\n      // Remove the removed values.\n      for (i = 0, n = removed.length; i < n; ++i) {\n        if (filters.only(k = removed[i], filterOffset, filterOne)) {\n          reduceValue = reduceRemove(reduceValue, data[k], notFilter);\n        }\n      }\n    }\n\n    // Recomputes the group reduce value from scratch.\n    function reset() {\n      var i;\n\n      reduceValue = reduceInitial();\n\n      // Cycle through all the values.\n      for (i = 0; i < n; ++i) {\n\n        // Add all values all the time.\n        reduceValue = reduceAdd(reduceValue, data[i], true);\n\n        // Remove the value if it is filtered.\n        if (!filters.zero(i)) {\n          reduceValue = reduceRemove(reduceValue, data[i], false);\n        }\n      }\n    }\n\n    // Sets the reduce behavior for this group to use the specified functions.\n    // This method lazily recomputes the reduce value, waiting until needed.\n    function reduce(add, remove, initial) {\n      reduceAdd = add;\n      reduceRemove = remove;\n      reduceInitial = initial;\n      resetNeeded = true;\n      return group;\n    }\n\n    // A convenience method for reducing by count.\n    function reduceCount() {\n      return reduce(xfilterReduce.reduceIncrement, xfilterReduce.reduceDecrement, cr_zero);\n    }\n\n    // A convenience method for reducing by sum(value).\n    function reduceSum(value) {\n      return reduce(xfilterReduce.reduceAdd(value), xfilterReduce.reduceSubtract(value), cr_zero);\n    }\n\n    // Returns the computed reduce value.\n    function value() {\n      if (resetNeeded) reset(), resetNeeded = false;\n      return reduceValue;\n    }\n\n    // Removes this group and associated event listeners.\n    function dispose() {\n      var i = filterListeners.indexOf(update);\n      if (i >= 0) filterListeners.splice(i, 1);\n      i = dataListeners.indexOf(add);\n      if (i >= 0) dataListeners.splice(i, 1);\n      return group;\n    }\n\n    return reduceCount();\n  }\n\n  // Returns the number of records in this crossfilter, irrespective of any filters.\n  function size() {\n    return n;\n  }\n\n  // Returns the raw row data contained in this crossfilter\n  function all(){\n    return data;\n  }\n\n  // Returns row data with all dimension filters applied, except for filters in ignore_dimensions\n  function allFiltered(ignore_dimensions) {\n    var array = [],\n        i = 0,\n        mask = maskForDimensions(ignore_dimensions || []);\n\n      for (i = 0; i < n; i++) {\n        if (filters.zeroExceptMask(i, mask)) {\n          array.push(data[i]);\n        }\n      }\n\n      return array;\n  }\n\n  function onChange(cb){\n    if(typeof cb !== 'function'){\n      /* eslint no-console: 0 */\n      console.warn('onChange callback parameter must be a function!');\n      return;\n    }\n    callbacks.push(cb);\n    return function(){\n      callbacks.splice(callbacks.indexOf(cb), 1);\n    };\n  }\n\n  function triggerOnChange(eventName){\n    for (var i = 0; i < callbacks.length; i++) {\n      callbacks[i](eventName);\n    }\n  }\n\n  return arguments.length\n      ? add(arguments[0])\n      : crossfilter;\n}\n\n// Returns an array of size n, big enough to store ids up to m.\nfunction cr_index(n, m) {\n  return (m < 0x101\n      ? xfilterArray.array8 : m < 0x10001\n      ? xfilterArray.array16\n      : xfilterArray.array32)(n);\n}\n\n// Constructs a new array of size n, with sequential values from 0 to n - 1.\nfunction cr_range(n) {\n  var range = cr_index(n, n);\n  for (var i = -1; ++i < n;) range[i] = i;\n  return range;\n}\n\nfunction capacity(w) {\n  return w === 8\n      ? 0x100 : w === 16\n      ? 0x10000\n      : 0x100000000;\n}\n","import {d3} from './lib';\nimport crossfilter from 'crossfilter2';\n\n/* Decompresses ideogram's annotations for crossfilter initialization\nBy default, annotations are clustered by chromosome, e.g.\n[\n  {\"chr\": \"1\", \"annots\": [{\"from\": 100, \"to\", 101, \"chr\": \"1\", ...}, ...]},\n  {\"chr\": \"2\", \"annots\": [{\"from\": 500, \"to\", 501, \"chr\": \"2\", ...}, ...]},\n  ...\n]\nThis method flattens that structure to e.g.\n[\n  {\"from\": 100, \"to\": 101, \"chr\": \"1\", ...},\n  ...\n  {\"from\": 500, \"to\": 501, \"chr\": \"2\", ...},\n]\nSee also: packAnnots\n*/\nfunction unpackAnnots() {\n  var chr, annots, i,\n    unpackedAnnots = [],\n    ideo = this,\n    chrs = ideo.annots;\n\n  for (i = 0; i < chrs.length; i++) {\n    chr = chrs[i];\n    annots = chr.annots;\n    unpackedAnnots = unpackedAnnots.concat(annots);\n  }\n\n  return unpackedAnnots;\n}\n\n/*\n  Compresses annots back to default state.  Inverse of unpackAnnots.\n*/\nfunction packAnnots(unpackedAnnots) {\n  var chr, annot, i,\n    annots = [],\n    ideo = this,\n    chrs = ideo.annots;\n\n  for (chr in chrs) {\n    annots.push({chr: chrs[chr].chr, annots: []});\n  }\n\n  for (i = 0; i < unpackedAnnots.length; i++) {\n    annot = unpackedAnnots[i];\n    annots[annot.chrIndex].annots.push(annot);\n  }\n\n  return annots;\n}\n\n/*\n  Initializes crossfilter.  Needed for client-side filtering.\n  More: https://github.com/square/crossfilter/wiki/API-Reference\n*/\nfunction initCrossFilter() {\n  var i, facet,\n    ideo = this,\n    keys = ideo.rawAnnots.keys;\n\n  ideo.unpackedAnnots = ideo.unpackAnnots();\n  ideo.crossfilter = crossfilter(ideo.unpackedAnnots);\n\n  ideo.annotsByFacet = {};\n  ideo.facets = keys.slice(3, keys.length);\n\n  for (i = 0; i < ideo.facets.length; i++) {\n    facet = ideo.facets[i];\n    ideo.annotsByFacet[facet] =\n      ideo.crossfilter.dimension(function(d) {\n        return d[facet];\n      });\n  }\n\n  if ('filterSelections' in ideo) {\n    ideo.filterAnnots(ideo.filterSelections);\n  }\n\n  ideo.filteredAnnots = ideo.annots;\n}\n\nfunction getFilteredResults(selections, ideo) {\n  var fn, i, facet, results, filter,\n    counts = {};\n\n  if (Object.keys(selections).length === 0) {\n    results = ideo.unpackedAnnots;\n  } else {\n    for (i = 0; i < ideo.facets.length; i++) {\n      facet = ideo.facets[i];\n      if (facet in selections) {\n        filter = selections[facet];\n        if (Array.isArray(filter)) {\n          fn = function(d) {\n            // Filter is numeric range\n            if (filter.length === 2) {\n              // [min, max]\n              return filter[0] <= d && d < filter[1];\n            } else if (filter.length === 4) {\n              // [min1, max1, min2, max2]\n              return (\n                filter[0] <= d && d < filter[1] ||\n                filter[2] <= d && d < filter[3]\n              );\n            }\n          };\n        } else {\n          fn = function(d) {\n            // Filter is set of categories\n            return (d in filter);\n          };\n        }\n      } else {\n        fn = null;\n      }\n      ideo.annotsByFacet[facet].filter(fn);\n      counts[facet] = ideo.annotsByFacet[facet].group().top(Infinity);\n    }\n    results = ideo.annotsByFacet[facet].top(Infinity);\n  }\n\n  return [results, counts];\n}\n\n/*\n  Filters annotations based on the given selections.\n  \"selections\" is an object of objects, e.g.\n\n    {\n      \"tissue-type\": {          <-- a facet\n        \"cerebral-cortex\": 1,   <-- a filter; \"1\" means it is selected\n        \"liver\": 1\n      },\n      \"gene-type\": {\n        mirna\": 1\n      }\n    }\n\n  Translation:\n  select where:\n      (tissue-type is cerebral-cortex OR liver) and (gene-type is mirna)\n\n  TODO:\n    * Filter counts\n    * Integrate server-side filtering for very large datasets\n*/\nfunction filterAnnots(selections) {\n  var i, facet, results, counts,\n    t0 = Date.now(),\n    ideo = this;\n\n  ideo.filterSelections = selections;\n  [results, counts] = getFilteredResults(selections, ideo);\n\n  for (i < 0; i < ideo.facets.length; i++) {\n    ideo.annotsByFacet[facet].filterAll(); // clear filters\n  }\n\n  results = ideo.packAnnots(results);\n\n  delete ideo.maxAnnotsPerBar;\n  delete ideo.maxAnnotsPerBarAllChrs;\n\n  ideo.filteredAnnots = results;\n\n  d3.selectAll(ideo.selector + ' polygon.annot').remove();\n  ideo.drawAnnots(results);\n\n  console.log('Time in filterAnnots: ' + (Date.now() - t0) + ' ms');\n\n  return counts;\n}\n\nexport {unpackAnnots, packAnnots, initCrossFilter, filterAnnots};\n","function getPixelAndOtherData(bands, chr, hasBands, ideo) {\n  var i, band, csLength, width, maxLength,\n    pxStop = 0,\n    taxid = chr.id.split('-')[1],\n    cs = ideo.coordinateSystem,\n    chrHeight = ideo.config.chrHeight;\n\n  for (i = 0; i < bands.length; i++) {\n    band = bands[i];\n    csLength = band[cs].stop - band[cs].start;\n\n    // If ideogram is rotated (and thus showing only one chromosome),\n    // then set its width independent of the longest chromosome in this\n    // genome.\n    if (ideo._layout._isRotated) {\n      width = chrHeight * csLength / chr.length;\n    } else {\n      if (ideo.config.chromosomeScale === 'relative') {\n        maxLength = ideo.maxLength[taxid][cs];\n      } else {\n        maxLength = ideo.maxLength[cs];\n      }\n      width = chrHeight * chr.length / maxLength * csLength / chr.length;\n    }\n    bands[i].px = {start: pxStop, stop: pxStop + width, width: width};\n\n    pxStop = bands[i].px.stop;\n\n    if (hasBands && band.stain === 'acen' && band.name[0] === 'p') {\n      chr.pcenIndex = i;\n    }\n  }\n  return [bands, chr, pxStop];\n}\n\n/**\n * TODO:\n * A chromosome-level scale property is likely\n * nonsensical for any chromosomes that have cytogenetic band data.\n * Different bands tend to have ratios between number of base pairs\n * and physical length.\n *\n * However, a chromosome-level scale property is likely\n * necessary for chromosomes that do not have band data.\n *\n * This needs further review.\n */\nfunction getChrScale(chr, hasBands, ideo) {\n  var chrHeight = ideo.config.chrHeight,\n    chrLength = chr.length,\n    maxLength = ideo.maxLength,\n    taxid = chr.id.split('-')[1],\n    scale = {};\n\n  scale.bp = chrHeight / maxLength.bp;\n\n  if (ideo.config.multiorganism === true) {\n    // chr.scale.bp = band.iscn.stop / band.bp.stop;\n    if (ideo.config.chromosomeScale === 'relative') {\n      scale.iscn = chrHeight * chrLength / maxLength[taxid].bp;\n      scale.bp = chrHeight / maxLength[taxid].bp;\n    } else {\n      scale.iscn = chrHeight * chrLength / maxLength.bp;\n    }\n  } else if (hasBands) {\n    scale.iscn = chrHeight / maxLength.iscn;\n  }\n\n  return scale;\n}\n\nfunction getChromosomePixels(chr) {\n  var bands, chrHeight, pxStop, hasBands, maxLength,\n    taxid = chr.id.split('-')[1],\n    ideo = this;\n\n  bands = chr.bands;\n  chrHeight = ideo.config.chrHeight;\n  pxStop = 0;\n  hasBands = (typeof bands !== 'undefined');\n\n  if (hasBands) {\n    [bands, chr, pxStop] = getPixelAndOtherData(bands, chr, hasBands, ideo);\n  } else {\n    if (ideo.config.chromosomeScale === 'relative') {\n      maxLength = ideo.maxLength[taxid][ideo.coordinateSystem];\n    } else {\n      maxLength = ideo.maxLength[ideo.coordinateSystem];\n    }\n    pxStop = chrHeight * chr.length / maxLength;\n  }\n\n  chr.width = pxStop;\n  chr.scale = getChrScale(chr, hasBands, ideo);\n  chr.bands = bands;\n\n  return chr;\n}\n\nfunction getChrModelScaffold(chr, bands, chrName, ideo) {\n  var hasBands = (typeof bands !== 'undefined');\n\n  if (hasBands) {\n    chr.name = chrName;\n    chr.length = bands[bands.length - 1][ideo.coordinateSystem].stop;\n    chr.type = 'nuclear';\n  } else {\n    chr = chrName;\n  }\n\n  return chr;\n}\n\n/**\n * Encountered when processing an assembly that has chromosomes with\n * centromere data, but this chromosome does not.\n * Example: chromosome F1 in Felis catus.\n */\nfunction deleteExtraneousBands(chr, hasBands) {\n  if (hasBands && chr.bands.length === 1) {\n    delete chr.bands;\n  }\n  return chr;\n}\n\nfunction getCentromerePosition(hasBands, bands) {\n\n  const hasTelocentricPArm = (\n    // As with almost all mouse chromosome, chimpanzee chr22\n    hasBands && bands[0].name[0] === 'p' && bands[1].name[0] === 'q' &&\n    bands[0].bp.stop - bands[0].bp.start < 2E6\n  );\n\n  let hasTelocentricQArm = false;\n  if (hasBands) {\n    // As with Macaca mulatta chromosome Y\n    const lastBand = bands.slice(-1)[0];\n    const penultimateBand = bands.slice(-2)[0];\n\n    hasTelocentricQArm = (\n      hasBands && penultimateBand.name[0] === 'p' && lastBand.name[0] === 'q' &&\n      lastBand.bp.stop - lastBand.bp.start < 2E6\n    );\n  }\n\n  if (hasTelocentricPArm) {\n    // As with almost all mouse chromosome, chimpanzee chr22\n    return 'telocentric-p';\n  } else if (hasTelocentricQArm) {\n    return 'telocentric-q';\n  } else {\n    return '';\n  }\n}\n\n/**\n * Generates a model object for each chromosome containing information on\n * its name, DOM ID, length in base pairs or ISCN coordinates, cytogenetic\n * bands, centromere position, etc.\n */\nfunction getChromosomeModel(bands, chrName, taxid, chrIndex) {\n  var hasBands, org,\n    chr = {},\n    ideo = this;\n\n  hasBands = (typeof bands !== 'undefined');\n\n  chr = getChrModelScaffold(chr, bands, chrName, ideo);\n\n  chr.chrIndex = chrIndex;\n  chr.id = 'chr' + chr.name + '-' + taxid;\n\n  if (ideo.config.fullChromosomeLabels === true) {\n    org = this.organisms[taxid];\n    chr.name = org.scientificName + ' chr' + chr.name;\n  }\n\n  chr.bands = bands;\n  chr = ideo.getChromosomePixels(chr);\n  chr.centromerePosition = getCentromerePosition(hasBands, bands);\n\n  chr = deleteExtraneousBands(chr, hasBands);\n\n  return chr;\n}\n\nexport {getChromosomeModel, getChromosomePixels};\n","/* eslint-disable no-use-before-define */\n\nexport class ModelAdapter {\n\n  constructor(model) {\n    this._model = model;\n    this._class = 'ModelAdapter';\n  }\n\n  static getInstance(model) {\n    if (model.bands) {\n      return new ModelAdapter(model);\n    } else {\n      return new ModelNoBandsAdapter(model);\n    }\n  }\n\n  getModel() {\n    return this._model;\n  }\n\n  getCssClass() {\n    return '';\n  }\n}\n\nexport class ModelNoBandsAdapter extends ModelAdapter {\n\n  constructor(model) {\n    super(model);\n    this._class = 'ModelNoBandsAdapter';\n  }\n\n  getModel() {\n    this._model.bands = [];\n\n    // If chromosome width more than 1, add single band to bands array\n    if (this._model.width > 1) {\n      this._model.bands.push({\n        name: 'q',\n        px: {\n          start: 0,\n          stop: this._model.width,\n          width: this._model.width\n        },\n        bp: {\n          start: 1,\n          stop: this._model.length\n        }\n      });\n    }\n\n    return this._model;\n  }\n\n  getCssClass() {\n    return 'noBands';\n  }\n\n}\n","import {Ploidy} from './ploidy';\n\nexport class Color {\n\n  constructor(config) {\n    // Ideogram config\n    this._config = config;\n    this._ploidy = new Ploidy(this._config);\n  }\n\n  getArmColor(chrSetIndex, chrIndex, armIndex) {\n    if (this._config.armColors) {\n      return this._config.armColors[armIndex];\n    } else if (this._config.ancestors) {\n      return this._getPolyploidArmColor(chrSetIndex, chrIndex, armIndex);\n    } else {\n      return null;\n    }\n  }\n\n  getBorderColor(chrSetIndex, chrIndex, armIndex) {\n    if (chrIndex < this._config.ploidy) {\n      return '#000';\n    } else if (this._ploidy.exists(chrSetIndex, chrIndex, armIndex)) {\n      return '#000';\n    } else {\n      return '#fff';\n    }\n  }\n\n  _getPolyploidArmColor(chrSetIndex, chrIndex, armIndex) {\n    if (!this._ploidy.exists(chrSetIndex, chrIndex, armIndex)) {\n      return 'transparent';\n    } else {\n      var ancestor =\n        this._ploidy.getAncestor(chrSetIndex, chrIndex, armIndex);\n      return this._config.ancestors[ancestor];\n    }\n  }\n\n}\n","export class Range {\n\n  /**\n  * Chromosome range.\n  * @public\n  * @class\n  * @param {Object} data - range data.\n  * @param {Integer} data.chr - chromosome index.\n  * @param {Integer[]} [data.ploidy] - array which controls on which\n  *                                    chromosomes range should appear in case\n  *                                    of ploidy.\n  * @param {Integer} data.start - range start.\n  * @param {Integer} data.stop - range end.\n  * @param {String} data.color - range color.\n  */\n  constructor(data) {\n    this._data = data;\n    this.start = data.start;\n    this.stop = data.stop;\n    this.length = this.stop - this.start;\n  }\n\n  getColor(chrIndex) {\n    if (!('ploidy' in this._data)) {\n      return this._getColor(chrIndex);\n    } else if ('ploidy' in this._data && this._data.ploidy[chrIndex]) {\n      return this._getColor(chrIndex);\n    } else {\n      return 'transparent';\n    }\n  }\n\n  _getColor(chrIndex) {\n    if (Array.isArray(this._data.color)) {\n      return this._data.color[chrIndex];\n    } else {\n      return this._data.color;\n    }\n  }\n\n}\n","/* eslint-disable no-use-before-define */\nimport {Color} from './../color';\nimport {Range} from './../range';\n\nexport class Chromosome {\n\n  constructor(adapter, config, ideo) {\n    this._adapter = adapter;\n    this._model = this._adapter.getModel();\n    this._config = config;\n    this._ideo = ideo;\n    this._color = new Color(this._config);\n    this._bumpCoefficient = 5;\n  }\n\n  /**\n   * Factory method\n   */\n  static getInstance(adapter, config, ideo) {\n    const centromerePosition = adapter.getModel().centromerePosition;\n    if (centromerePosition === 'telocentric-p') {\n      return new TelocentricPChromosome(adapter, config, ideo);\n    } else if (centromerePosition === 'telocentric-q') {\n      return new TelocentricQChromosome(adapter, config, ideo);\n    } else {\n      return new MetacentricChromosome(adapter, config, ideo);\n    }\n  }\n\n  _addPArmShape(clipPath, isPArmRendered) {\n    if (isPArmRendered) {\n      return clipPath.concat(this._getPArmShape());\n    } else {\n      return clipPath;\n    }\n  }\n\n  _addQArmShape(clipPath, isQArmRendered) {\n    if (isQArmRendered) {\n      return clipPath.concat(this._getQArmShape());\n    } else {\n      return clipPath;\n    }\n  }\n\n  /**\n   * Append bands container and apply clip-path to it\n   */\n  render(container, chrSetIndex, chrIndex) {\n\n    var self, isPArmRendered, isQArmRendered, clipPath, opacity, fill,\n      isFullyBanded;\n\n    self = this;\n\n    container = container.append('g')\n      .attr('class', 'bands')\n      .attr('clip-path',\n        'url(#' + this._model.id + '-chromosome-set-clippath)'\n      );\n\n    // Render chromosome arms\n    isPArmRendered = this._renderArm(container, chrSetIndex, chrIndex, 'p');\n    isQArmRendered = this._renderArm(container, chrSetIndex, chrIndex, 'q');\n\n    // Render range set\n    this._renderRangeSet(container, chrSetIndex, chrIndex);\n\n    // Push arms shape string into clipPath array\n    clipPath = [];\n    clipPath = this._addPArmShape(clipPath, isPArmRendered);\n    clipPath = this._addQArmShape(clipPath, isQArmRendered);\n\n    opacity = '0';\n    fill = '';\n    isFullyBanded = this.isFullyBanded();\n    if (\n      'ancestors' in this._ideo.config &&\n      !('rangeSet' in this._ideo.config)\n    ) {\n      // E.g. diploid human genome (with translucent overlay)\n      fill = self._color.getArmColor(chrSetIndex, chrIndex, 0);\n      if (isFullyBanded) {\n        opacity = '0.5';\n      }\n    } else if (isFullyBanded) {\n      // E.g. mouse reference genome\n      opacity = null;\n      fill = 'transparent';\n    } else if (!('ancestors' in this._ideo.config)) {\n      // E.g. chimpanzee assembly Pan_tro 3.0\n      opacity = '1';\n    }\n\n    // Render chromosome border\n    container.append('g')\n      .attr('class', 'chromosome-border')\n      .selectAll('path')\n      .data(clipPath)\n      .enter()\n      .append('path')\n      .attr('fill', fill)\n      .style('fill-opacity', opacity)\n      .attr('stroke', function(d, i) {\n        return self._color.getBorderColor(chrSetIndex, chrIndex, i);\n      })\n      .attr('stroke-width', function(d) {\n        return ('strokeWidth' in d ? d.strokeWidth : 1);\n      })\n      .attr('d', function(d) {\n        return d.path;\n      }).attr('class', function(d) {\n        return d.class;\n      });\n\n    return clipPath;\n  }\n\n  _renderRangeSet(container, chrSetIndex, chrIndex) {\n\n    var self, rangeSet, rangesContainer, ideo;\n\n    if (!('rangeSet' in this._config)) {\n      return;\n    }\n\n    rangeSet = this._config.rangeSet.filter(function(range) {\n      return range.chr - 1 === chrSetIndex;\n    }).map(function(range) {\n      return new Range(range);\n    });\n\n    rangesContainer = container.append('g').attr('class', 'range-set');\n\n    self = this;\n    ideo = self._ideo;\n\n    rangesContainer.selectAll('rect.range')\n      .data(rangeSet)\n      .enter()\n      .append('rect')\n      .attr('class', 'range')\n      .attr('x', function(range) {\n        return ideo.convertBpToPx(self._model, range.start);\n      }).attr('y', 0)\n      .attr('width', function(range) {\n        return ideo.convertBpToPx(self._model, range.length);\n      }).attr('height', this._config.chrWidth)\n      .style('fill', function(range) {\n        return range.getColor(chrIndex);\n      });\n  }\n\n  /**\n   * Get chromosome's shape main values\n   */\n  _getShapeData() {\n\n    var firstQBand, i, lastBand, rightTerminalPosition;\n\n    // First q band from bands sequence\n    for (i = 0; i < this._model.bands.length; i++) {\n      if (this._model.bands[i].name[0] === 'q') {\n        firstQBand = this._model.bands[i];\n        break;\n      }\n    }\n\n    // Chromosome's right position\n    lastBand = this._model.bands.length - 1;\n    rightTerminalPosition = this._model.bands[lastBand].px.stop;\n\n    // Properties description:\n    // x1 - left terminal start position\n    // x2 - centromere position\n    // x3 - right terminal end position\n    // w - chromosome width\n    // b - bump size\n    return {\n      x1: 0,\n      x2: firstQBand ? firstQBand.px.start : rightTerminalPosition,\n      x3: rightTerminalPosition,\n      w: this._config.chrWidth,\n      b: this._config.chrWidth / this._bumpCoefficient\n    };\n  }\n\n  _getPArmShape() {\n    var d = this._getShapeData(),\n      x = d.x2 - d.b;\n\n    if (this.isFullyBanded() || 'ancestors' in this._ideo.config) {\n      // Encountered when chromosome has any of:\n      //  - One placeholder \"band\", e.g. pig genome GCF_000003025.5\n      //  - Many (> 2) bands, e.g. human reference genome\n      //  - Ancestor colors in ploidy configuration, as in ploidy-basic.html\n      return {\n        class: '',\n        path:\n          'M' + d.b + ',0 ' +\n          'L' + x + ',0 ' +\n          'Q' + (d.x2 + d.b) + ',' + (d.w / 2) + ',' + x + ',' + d.w + ' ' +\n          'L' + d.b + ',' + d.w + ' ' +\n          'Q-' + d.b + ',' + (d.w / 2) + ',' + d.b + ',0'\n      };\n    } else {\n      // e.g. chimpanzee assembly Pan_tro 3.0\n      return [{\n        class: '',\n        path:\n          'M' + d.b + ',0 ' +\n          'L' + (x - 2) + ',0 ' +\n          'L' + (x - 2) + ',' + d.w + ' ' +\n          'L' + d.b + ',' + d.w + ' ' +\n          'Q-' + d.b + ',' + (d.w / 2) + ',' + d.b + ',0'\n      }, {\n        class: 'acen',\n        path:\n          'M' + x + ',0 ' +\n          'Q' + (d.x2 + d.b) + ',' + (d.w / 2) + ',' + x + ',' + d.w + ' ' +\n          'L' + x + ',' + d.w + ' ' +\n          'L' + (x - 2) + ',' + d.w + ' ' +\n          'L' + (x - 2) + ',0'\n      }];\n    }\n  }\n\n  _getQArmShape() {\n    var d = this._getShapeData(),\n      x = d.x3 - d.b,\n      x2b = d.x2 + d.b;\n\n    if (this.isFullyBanded() || 'ancestors' in this._ideo.config) {\n      return {\n        class: '',\n        path:\n          'M' + x2b + ',0 ' +\n          'L' + x + ',0 ' +\n          'Q' + (d.x3 + d.b) + ',' + (d.w / 2) + ',' + x + ',' + d.w + ' ' +\n          'L' + x2b + ',' + d.w + ' ' +\n          'Q' + (d.x2 - d.b) + ',' + (d.w / 2) + ',' + x2b + ',0'\n      };\n    } else {\n      // e.g. chimpanzee assembly Pan_tro 3.0\n      return [{\n        path:\n          'M' + x2b + ',0 ' +\n          'L' + x + ',0 ' +\n          'Q' + (d.x3 + d.b) + ',' + (d.w / 2) + ',' + x + ',' + d.w + ' ' +\n          'L' + x2b + ',' + d.w + ' ' +\n          'L' + x2b + ',0'\n      }, {\n        class: 'acen',\n        path:\n          'M' + x2b + ',0' +\n          'Q' + (d.x2 - d.b) + ',' + (d.w / 2) + ',' + x2b + ',' + d.w + ' ' +\n          'L' + x2b + ',' + d.w +\n          'L' + (x2b + 2) + ',' + d.w +\n          'L' + (x2b + 2) + ',0'\n      }];\n    }\n  }\n\n  isFullyBanded() {\n    return (\n      this._model.bands &&\n      (this._model.bands.length !== 2 || this._model.bands[0].name[0] === 'q')\n    );\n  }\n\n  /**\n   * Render arm bands\n   */\n  _renderBands(container, chrSetIndex, chrIndex, bands, arm) {\n\n    var self, armIndex, fill;\n\n    self = this;\n    armIndex = arm === 'p' ? 0 : 1;\n    fill = '';\n\n    if ('ancestors' in self._ideo.config && !(self.isFullyBanded())) {\n      fill = self._color.getArmColor(chrSetIndex, chrIndex, armIndex);\n    }\n\n    container.selectAll('path.band.' + arm)\n      .data(bands)\n      .enter()\n      .append('path')\n      .attr('id', function(d) {\n        return self._model.id + '-' + d.name.replace('.', '-');\n      })\n      .attr('class', function(d) {\n        return 'band ' + arm + '-band ' + d.stain;\n      })\n      .attr('d', function(d) {\n        var start, length;\n\n        start = self._ideo.round(d.px.start);\n        length = self._ideo.round(d.px.width);\n\n        return 'M ' + start + ', 0' +\n              'l ' + length + ' 0 ' +\n              'l 0 ' + self._config.chrWidth + ' ' +\n              'l -' + length + ' 0 z';\n      })\n      .style('fill', fill);\n  }\n\n  /**\n   * Render a chromosome arm.\n   * Returns boolean indicating if any bands were rendered.\n   */\n  _renderArm(container, chrSetIndex, chrIndex, arm) {\n    var bands = this._model.bands.filter(function(band) {\n      return band.name[0] === arm;\n    });\n\n    this._renderBands(container, chrSetIndex, chrIndex, bands, arm);\n\n    return Boolean(bands.length);\n  }\n}\n\nexport class MetacentricChromosome extends Chromosome {\n\n  constructor(model, config, ideo) {\n    super(model, config, ideo);\n    this._class = 'MetacentricChromosome';\n  }\n}\n\nexport class TelocentricPChromosome extends Chromosome {\n\n  constructor(model, config, ideo) {\n    // alert('p')\n    super(model, config, ideo);\n    this._class = 'TelocentricPChromosome';\n    this._pArmOffset = 3;\n  }\n\n  _addPArmShape(clipPath) {\n    return clipPath.concat(this._getPArmShape());\n  }\n\n  _getPArmShape() {\n    // Properties description:\n    // x1 - left terminal start position\n    // x2 - centromere position\n    // x3 - right terminal end position\n    // w - chromosome width\n    // b - bump size\n    var d = this._getShapeData();\n    d.o = this._pArmOffset;\n\n    return [{\n      class: 'acen',\n      path: 'M' + (d.x2 + 2) + ',1' +\n      'L' + (d.x2 + d.o + 3.25) + ',1 ' +\n      'L' + (d.x2 + d.o + 3.25) + ',' + (d.w - 1) + ' ' +\n      'L' + (d.x2 + 2) + ',' + (d.w - 1)\n    }, {\n      class: 'gpos66',\n      path: 'M' + (d.x2 - d.o + 5) + ',0' +\n      'L' + (d.x2 - d.o + 3) + ',0 ' +\n      'L' + (d.x2 - d.o + 3) + ',' + d.w + ' ' +\n      'L' + (d.x2 - d.o + 5) + ',' + d.w,\n      strokeWidth: 0.5\n    }];\n  }\n\n  _getQArmShape() {\n    // Properties description:\n    // x1 - left terminal start position\n    // x2 - centromere position\n    // x3 - right terminal end position\n    // w - chromosome width\n    // b - bump size\n    var d = this._getShapeData(),\n      x = d.x3 - d.b,\n      o = this._pArmOffset + 3;\n\n    return {\n      class: '',\n      path:\n      'M' + (d.x2 + o) + ',0 ' +\n      'L' + x + ',0 ' +\n      'Q' + (d.x3 + d.b) + ',' + (d.w / 2) + ',' + x + ',' + d.w + ' ' +\n      'L' + (d.x2 + o) + ',' + d.w\n    };\n  }\n}\n\nexport class TelocentricQChromosome extends Chromosome {\n\n  constructor(model, config, ideo) {\n    // alert('q')\n    super(model, config, ideo);\n    this._class = 'TelocentricQChromosome';\n    this._qArmOffset = 3;\n  }\n\n  _getPArmShape() {\n    // Properties description:\n    // x1 - left terminal start position\n    // x2 - centromere position\n    // x3 - right terminal end position\n    // w - chromosome width\n    // b - bump size\n\n    var d = this._getShapeData(),\n      x = d.x3 - d.b,\n      o = this._qArmOffset;\n\n    return {\n      class: '',\n      path:\n      // 'M1,0, ' +\n      'M' + (d.x2 + o) + ',0 ' +\n      'L' + (x + o) + ',0 ' +\n      'L' + (x + o) + ',' + d.w + ' ' +\n      'L' + d.b + ',' + d.w + ' ' +\n      'Q-' + d.b + ',' + (d.w / 2) + ',' + d.b + ',0'\n    };\n  }\n\n  _addQArmShape(clipPath) {\n    return clipPath.concat(this._getQArmShape());\n  }\n\n  _getQArmShape() {\n    // Properties description:\n    // x1 - left terminal start position\n    // x2 - centromere position\n    // x3 - right terminal end position\n    // w - chromosome width\n    // b - bump size\n    var d = this._getShapeData();\n    d.o = this._qArmOffset;\n\n    return [{\n      class: 'acen',\n      path: 'M' + (d.x2 + 2) + ',1 ' +\n      'L' + (d.x2 + d.o + 3.25) + ',1 ' +\n      'L' + (d.x2 + d.o + 3.25) + ',' + (d.w - 1) + ' ' +\n      'L' + (d.x2 + 2) + ',' + (d.w - 1)\n    }, {\n      class: 'gpos66',\n      path: 'M' + (d.x2 + d.o + 5) + ',0 ' +\n      'L' + (d.x2 + d.o + 3) + ',0 ' +\n      'L' + (d.x2 + d.o + 3) + ',' + d.w + ' ' +\n      'L' + (d.x2 + d.o + 5) + ',' + d.w,\n      strokeWidth: 0.5\n    }];\n  }\n}\n","import {d3} from '../lib';\n// import {initSettings} from '../init/settings-ui';\nimport {ModelAdapter} from '../model-adapter';\nimport {Chromosome} from './chromosome';\n\n/**\n * Adds a copy of a chromosome (i.e. a homologous chromosome, homolog) to DOM\n *\n * @param chrModel\n * @param chrIndex\n * @param homologIndex\n * @param container\n */\nfunction appendHomolog(chrModel, chrIndex, homologIndex, container) {\n\n  var homologOffset, chromosome, shape, defs, adapter;\n\n  defs = d3.select(this.selector + ' defs');\n  // Get chromosome model adapter class\n  adapter = ModelAdapter.getInstance(chrModel);\n\n  // How far this copy of the chromosome is from another\n  homologOffset = homologIndex * this.config.chrMargin;\n\n  // Append chromosome's container\n  chromosome = container\n    .append('g')\n    .attr('id', chrModel.id)\n    .attr('class', 'chromosome ' + adapter.getCssClass())\n    .attr('transform', 'translate(0, ' + homologOffset + ')');\n\n  // Render chromosome\n  shape = Chromosome.getInstance(adapter, this.config, this)\n    .render(chromosome, chrIndex, homologIndex);\n\n  d3.select('#' + chrModel.id + '-chromosome-set-clippath').remove();\n\n  defs.append('clipPath')\n    .attr('id', chrModel.id + '-chromosome-set-clippath')\n    .selectAll('path')\n    .data(shape)\n    .enter()\n    .append('path')\n    .attr('d', function(d) {return d.path;})\n    .attr('class', function(d) {return d.class;});\n}\n\n/**\n * Renders all the bands and outlining boundaries of a chromosome.\n */\nfunction drawChromosome(chrModel) {\n  var chrIndex, container, numChrsInSet, transform, homologIndex,\n    chrSetSelector;\n\n  chrIndex = chrModel.chrIndex;\n\n  transform = this._layout.getChromosomeSetTranslate(chrIndex);\n\n  chrSetSelector = this.selector + ' #' + chrModel.id + '-chromosome-set';\n\n  d3.selectAll(chrSetSelector + ' g').remove();\n\n  container = d3.select(chrSetSelector);\n\n  if (container.nodes().length === 0) {\n    // Append chromosome set container\n    container = d3.select(this.selector)\n      .append('g')\n      .attr('class', 'chromosome-set')\n      .attr('transform', transform)\n      .attr('id', chrModel.id + '-chromosome-set');\n  }\n\n  if (\n    'sex' in this.config &&\n    this.config.ploidy === 2 &&\n    this.sexChromosomes.index === chrIndex\n  ) {\n    this.drawSexChromosomes(container, chrIndex);\n    return;\n  }\n\n  numChrsInSet = 1;\n  if (this.config.ploidy > 1) {\n    numChrsInSet = this._ploidy.getChromosomesNumber(chrIndex);\n  }\n\n  for (homologIndex = 0; homologIndex < numChrsInSet; homologIndex++) {\n    this.appendHomolog(chrModel, chrIndex, homologIndex, container);\n  }\n}\n\n/**\n * Rotates a chromosome 90 degrees and shows or hides all other chromosomes\n * Useful for focusing or defocusing a particular chromosome\n */\nfunction rotateAndToggleDisplay(chrElement) {\n  var chrName, chrModel, chrIndex;\n\n  // Do nothing if taxid not defined. But it should be defined.\n  // To fix that bug we should have a way to find chromosome set number.\n  if (!this.config.taxid) return;\n\n  chrName = chrElement.id.split('-')[0].replace('chr', '');\n  chrModel = this.chromosomes[this.config.taxid][chrName];\n  chrIndex = chrModel.chrIndex;\n\n  this._layout.rotate(chrIndex, chrIndex, chrElement);\n}\n\nfunction setOverflowScroll() {\n  var ideo, config, ideoWidth, ideoInnerWrap, ideoMiddleWrap, ideoSvg,\n    ploidy, ploidyPad;\n\n  ideo = this;\n  config = ideo.config;\n\n  ideoSvg = d3.select(config.container + ' svg#_ideogram');\n  ideoInnerWrap = d3.select(config.container + ' #_ideogramInnerWrap');\n  ideoMiddleWrap = d3.select(config.container + ' #_ideogramMiddleWrap');\n\n  ploidy = config.ploidy;\n  if (ploidy === 1) {\n    ploidyPad = ploidy;\n  } else {\n    ploidyPad = ploidy * 1.12;\n  }\n\n  let annotHeight = 0;\n  if ('annotationsLayout' in config) {\n    annotHeight = config.annotationHeight * config.numAnnotTracks;\n  }\n\n  if (\n    config.orientation === 'vertical' &&\n    config.perspective !== 'comparative' &&\n    config.geometry !== 'collinear'\n  ) {\n    ideoWidth =\n      (ideo.numChromosomes) *\n      (config.chrWidth + config.chrMargin + annotHeight);\n  } else {\n    return;\n  }\n\n  if (config.annotationsLayout === 'heatmap-2d') {\n    return;\n  }\n\n  ideoWidth = Math.ceil(ideoWidth * ploidyPad / config.rows);\n  if (ideo._layout._class === 'SmallLayout') ideoWidth += 100;\n\n  ideoWidth += 35; // Account for settings gear\n\n  // Ensures absolutely-positioned elements, e.g. heatmap overlaps, display\n  // properly if ideogram container also has position: absolute\n  ideoMiddleWrap.style('height', ideo._layout.getHeight() + 'px');\n\n  ideoInnerWrap\n    .style('max-width', ideoWidth + 'px')\n    .style('overflow-x', 'scroll')\n    .style('position', 'absolute');\n\n  ideoSvg.style('min-width', (ideoWidth - 5) + 'px');\n\n  // initSettings(ideo);\n}\n\nexport {\n  appendHomolog, drawChromosome, rotateAndToggleDisplay, setOverflowScroll\n};\n","import {d3} from '../lib';\n\nfunction getChrSetLabelLines(d, i, ideo) {\n  var lines;\n  if (d.name.indexOf(' ') === -1) {\n    lines = [d.name];\n  } else {\n    lines = d.name.match(/^(.*)\\s+([^\\s]+)$/).slice(1).reverse();\n  }\n\n  if (\n    'sex' in ideo.config &&\n    ideo.config.ploidy === 2 &&\n    i === ideo.sexChromosomes.index\n  ) {\n    if (ideo.config.sex === 'male') {\n      lines = ['XY'];\n    } else {\n      lines = ['XX'];\n    }\n  }\n\n  return lines;\n}\n\nfunction renderChromosomeSetLabel(d, i, textElement, ideo) {\n  // Get label lines\n  var lines = getChrSetLabelLines(d, i, ideo);\n\n  // Render label lines\n  d3.select(textElement).selectAll('tspan')\n    .data(lines)\n    .enter()\n    .append('tspan')\n    .attr('dy', function(d, i) {\n      return i * -1.2 + 'em';\n    })\n    .attr('x', ideo._layout.getChromosomeSetLabelXPosition())\n    .attr('class', function(a, i) {\n      var fullLabels = ideo.config.fullChromosomeLabels;\n      return i === 1 && fullLabels ? 'italic' : null;\n    })\n    .text(String);\n}\n\nfunction appendChromosomeSetLabels(ideo) {\n  var layout = ideo._layout;\n\n  d3.selectAll(ideo.selector + ' .chromosome-set')\n    .insert('text', ':first-child')\n    .data(ideo.chromosomesArray)\n    .attr('class', layout.getChromosomeLabelClass())\n    .attr('transform', layout.getChromosomeSetLabelTranslate())\n    .attr('x', layout.getChromosomeSetLabelXPosition())\n    .attr('y', function(d, i) {\n      return layout.getChromosomeSetLabelYPosition(i);\n    })\n    .attr('text-anchor', layout.getChromosomeSetLabelAnchor())\n    .each(function(d, i) {\n      renderChromosomeSetLabel(d, i, this, ideo);\n    });\n}\n\nfunction appendChromosomeLabels(ideo) {\n  var layout = ideo._layout;\n\n  d3.selectAll(ideo.selector + ' .chromosome-set')\n    .each(function(a, chrSetIndex) {\n      d3.select(this).selectAll('.chromosome')\n        .append('text')\n        .attr('class', 'chrLabel')\n        .attr('transform', layout.getChromosomeSetLabelTranslate())\n        .attr('x', function(d, i) {\n          return layout.getChromosomeLabelXPosition(i);\n        })\n        .attr('y', function(d, i) {\n          return layout.getChromosomeLabelYPosition(i);\n        })\n        .text(function(d, chrIndex) {\n          return ideo._ploidy.getAncestor(chrSetIndex, chrIndex);\n        })\n        .attr('text-anchor', 'middle');\n    });\n}\n\n/**\n * Draws labels for each chromosome, e.g. \"1\", \"2\", \"X\".\n * If ideogram configuration has 'fullChromosomeLabels: True',\n * then labels includes name of taxon, which can help when\n * depicting orthologs.\n */\nfunction drawChromosomeLabels() {\n  var ideo = this;\n  appendChromosomeSetLabels(ideo);\n  appendChromosomeLabels(ideo);\n}\n\nfunction getLabelPositionAttrs(scale) {\n  var x, y, scaleSvg;\n\n  if (\n    typeof (scale) !== 'undefined' &&\n    scale.hasOwnProperty('x') &&\n    !(scale.x === 1 && scale.y === 1)\n  ) {\n    scaleSvg = 'scale(' + scale.x + ',' + scale.y + ')';\n    x = -6;\n    y = (scale === '' ? -16 : -14);\n  } else {\n    x = -8;\n    y = -16;\n    scale = {x: 1, y: 1};\n    scaleSvg = '';\n  }\n\n  return {x: x, y: y, scaleSvg: scaleSvg, scale: scale};\n}\n\nfunction updateChrIndex(chrIndex, config) {\n  if (config.numAnnotTracks > 1 || config.orientation === '') chrIndex -= 1;\n  return chrIndex;\n}\n\nfunction rotateVerticalChromosomeLabels(chr, chrIndex, labelPosAttrs, ideo) {\n  var chrMargin2, chrMargin, y,\n    config = ideo.config;\n\n  chrIndex = updateChrIndex(chrIndex, config);\n\n  chrMargin2 = -4;\n  if (config.showBandLabels === true) {\n    chrMargin2 = config.chrMargin + config.chrWidth + 26;\n  }\n\n  chrMargin = config.chrMargin * chrIndex;\n  if (config.numAnnotTracks > 1 === false) chrMargin += 1;\n\n  y = chrMargin + chrMargin2;\n\n  chr.selectAll('text.chrLabel')\n    .attr('transform', labelPosAttrs.scaleSvg)\n    .selectAll('tspan')\n    .attr('x', labelPosAttrs.x)\n    .attr('y', y);\n}\n\nfunction rotateHorizontalChromosomeLabels(chr, chrIndex, labelPosAttrs, ideo) {\n  var chrMargin, chrMargin2, tracksHeight, x,\n    config = ideo.config;\n\n  chrMargin2 = -config.chrWidth - 2;\n  if (config.showBandLabels === true) chrMargin2 = config.chrMargin + 8;\n\n  tracksHeight = config.annotTracksHeight;\n  if (config.annotationsLayout !== 'overlay') tracksHeight *= 2;\n\n  chrMargin = config.chrMargin * chrIndex;\n  x = -(chrMargin + chrMargin2) + 3 + tracksHeight;\n  x /= labelPosAttrs.scale.x;\n\n  chr.selectAll('text.chrLabel')\n    .attr('transform', 'rotate(-90)' + labelPosAttrs.scaleSvg)\n    .selectAll('tspan')\n    .attr('x', x)\n    .attr('y', labelPosAttrs.y);\n}\n\n/**\n * Rotates chromosome labels by 90 degrees, e.g. upon clicking a chromosome.\n */\nfunction rotateChromosomeLabels(chr, chrIndex, orientation, scale) {\n  var labelPosAttrs,\n    ideo = this;\n\n  chrIndex -= 1;\n\n  labelPosAttrs = getLabelPositionAttrs(scale);\n\n  if (orientation === 'vertical' || orientation === '') {\n    rotateVerticalChromosomeLabels(chr, chrIndex, labelPosAttrs, ideo);\n  } else {\n    rotateHorizontalChromosomeLabels(chr, chrIndex, labelPosAttrs, ideo);\n  }\n}\n\nexport {drawChromosomeLabels, rotateChromosomeLabels};\n","/**\n * @fileoverview Kit used in \"Related genes\" example\n *\n * This file simplifies client code for reusing a \"related genes\" ideogram --\n * which finds and displays related genes for a searched gene.\n *\n * Related genes here are either \"interacting genes\" or \"paralogs\".\n * Interacting genes are genes that immediate upstream or downstream of the\n * searched gene in a biochemical pathway. Paralogs are evolutionarily\n * similar genes in the same species.\n *\n * Data sources:\n *   - Interacting genes: WikiPathways\n *   - Paralogs: Ensembl\n *   - Genomic coordinates: Ensembl, via MyGene.info\n *\n * Features provided by this module help users discover and explore genes\n * related to their gene of interest.\n *\n * The reference implementation is available at:\n * https://eweitz.github.io/ideogram/related-genes\n */\n\n/**\n * Determines if interaction node might be a gene\n *\n * Some interaction nodes are biological processes; this filters out many.\n * Filtering these out makes downstream queries faster.\n *\n * ixn {Object} Interaction from WikiPathways\n * gene {Object} Gene from MyGene.info\n */\nfunction maybeGeneSymbol(ixn, gene) {\n  return (\n    ixn !== '' &&\n    !ixn.includes(' ') &&\n    !ixn.includes('/') && // e.g. Akt/PKB\n    ixn.toLowerCase() !== gene.name.toLowerCase()\n  );\n}\n\n/**\n * Retrieves interacting genes from WikiPathways API\n *\n * Docs:\n * https://webservice.wikipathways.org/ui/\n * https://www.wikipathways.org/index.php/Help:WikiPathways_Webservice/API\n *\n * Examples:\n * https://webservice.wikipathways.org/findInteractions?query=ACE2&format=json\n * https://webservice.wikipathways.org/findInteractions?query=RAD51&format=json\n */\nasync function fetchInteractingGenes(gene, ideo) {\n  const ixns = {};\n  const seenNameIds = {};\n  const orgNameSimple = ideo.config.organism.replace(/-/g, ' ');\n  const queryString = `?query=${gene.name}&format=json`;\n  const url =\n    `https://webservice.wikipathways.org/findInteractions${queryString}`;\n\n  const response = await fetch(url);\n  const data = await response.json();\n\n  // For each interaction, get nodes immediately upstream and downstream.\n  // Filter out pathway nodes that are definitely not gene symbols, then\n  // group pathways by (likely) gene symbol. Each interacting gene can have\n  // multiple pathways.\n  data.result.forEach(interaction => {\n    if (interaction.species.toLowerCase() === orgNameSimple) {\n      const right = interaction.fields.right.values;\n      const left = interaction.fields.left.values;\n      const rawIxns = right.concat(left);\n      const name = interaction.name;\n      const id = interaction.id;\n\n      rawIxns.forEach(rawIxn => {\n        const nameId = name + id;\n        if (maybeGeneSymbol(rawIxn, gene) && !(nameId in seenNameIds)) {\n          seenNameIds[nameId] = 1;\n          const ixn = {name: name, pathwayId: id};\n          if (rawIxn in ixns) {\n            ixns[rawIxn].push(ixn);\n          } else {\n            ixns[rawIxn] = [ixn];\n          }\n        }\n      });\n    }\n  });\n\n  return ixns;\n}\n\n/**\n * Queries MyGene.info API, returns parsed JSON\n *\n * Docs:\n * https://docs.mygene.info/en/v3/\n *\n * Example:\n * https://mygene.info/v3/query?q=symbol:cdk2%20OR%20symbol:brca1&species=9606&fields=symbol,genomic_pos,name\n */\nasync function fetchMyGeneInfo(queryString) {\n  const myGeneBase = 'https://mygene.info/v3/query';\n  const response = await fetch(myGeneBase + queryString);\n  const data = await response.json();\n  return data;\n}\n\n/**\n * Summarizes interactions for a gene\n *\n * This comprises most of the content for tooltips for interacting genes.\n */\nfunction describeInteractions(gene, ixns) {\n\n  let description = gene.name;\n\n  if (typeof ixns !== 'undefined') {\n    // ixns is undefined when querying e.g. CDKN1B in human\n    const pathwaysBase = 'https://www.wikipathways.org/index.php/Pathway:';\n    const links = ixns.map(ixn => {\n      const url = `${pathwaysBase}${ixn.pathwayId}`;\n      return `<a href=\"${url}\" target=\"_blank\">${ixn.name}</a>`;\n    }).join('<br/>');\n\n    let pathwayText = 'pathway';\n    if (ixns.length > 1) pathwayText += 's';\n\n    description += `\n      <br/><br/>\n      Interacts in ${pathwayText}:<br/>\n      ${links}`;\n  }\n\n  return description;\n}\n\n/**\n * Retrieves position and other data on interacting genes from MyGene.info\n */\nasync function fetchInteractingGeneAnnots(interactions, ideo) {\n\n  const annots = [];\n  const geneList = Object.keys(interactions);\n\n  if (geneList.length === 0) return annots;\n\n  const ixnParam = geneList.map(ixn => {\n    return `symbol:${ixn.trim()}`;\n  }).join(' OR ');\n\n  const taxid = ideo.config.taxid;\n  const queryString =\n    `?q=${ixnParam}&species=${taxid}&fields=symbol,genomic_pos,name`;\n  const data = await fetchMyGeneInfo(queryString);\n\n  data.hits.forEach(gene => {\n\n    // If hit lacks position, skip processing\n    if ('genomic_pos' in gene === false) return;\n\n    const annot = parseAnnotFromMgiGene(gene, ideo, 'purple');\n    annots.push(annot);\n\n    const ixns = interactions[gene.symbol];\n\n    const description = describeInteractions(gene, ixns);\n\n    ideo.annotDescriptions[gene.symbol] = description;\n  });\n\n  return annots;\n}\n\n/**\n * Fetch paralogs of searched gene\n */\nasync function fetchParalogPositions(annot, annots, ideo) {\n  const taxid = ideo.config.taxid;\n  const orgUnderscored = ideo.config.organism.replace(/[ -]/g, '_');\n\n  const params = `&format=condensed&type=paralogues&target_taxon=${taxid}`;\n  let path = `/homology/id/${annot.id}?${params}`;\n  const ensemblHomologs = await Ideogram.fetchEnsembl(path);\n  const homologs = ensemblHomologs.data[0].homologies;\n\n  // Fetch positions of paralogs\n  const homologIds = homologs.map(homolog => homolog.id);\n  path = '/lookup/id/' + orgUnderscored;\n  const body = {\n    ids: homologIds,\n    species: orgUnderscored,\n    object_type: 'gene'\n  };\n  const ensemblHomologGenes = await Ideogram.fetchEnsembl(path, body, 'POST');\n\n  Object.entries(ensemblHomologGenes).map((idGene, i) => {\n    const gene = idGene[1];\n\n    // Seen in related genes for SIRT2 in Pan troglodytes\n    if ('display_name' in gene === false) return;\n\n    const annot = {\n      name: gene.display_name,\n      chr: gene.seq_region_name,\n      start: gene.start,\n      stop: gene.end,\n      id: gene.id,\n      color: 'pink'\n    };\n\n    // Add to start of array, so searched gene gets top z-index\n    annots.unshift(annot);\n    ideo.annotDescriptions[annot.name] = gene.description;\n  });\n\n  return annots;\n}\n\n/**\n * Transforms MyGene.info (MGI) gene into Ideogram annotation\n */\nfunction parseAnnotFromMgiGene(gene, ideo, color='red') {\n  // Filters out placements on alternative loci scaffolds, an advanced\n  // genome assembly feature we are not concerned with in ideograms.\n  //\n  // Example:\n  // https://mygene.info/v3/query?q=symbol:PTPRC&species=9606&fields=symbol,genomic_pos,name\n  let genomicPos = null;\n  if (Array.isArray(gene.genomic_pos)) {\n    genomicPos = gene.genomic_pos.filter(pos => {\n      return pos.chr in ideo.chromosomes[ideo.config.taxid];\n    })[0];\n  } else {\n    genomicPos = gene.genomic_pos;\n  }\n\n  const annot = {\n    name: gene.symbol,\n    chr: genomicPos.chr,\n    start: genomicPos.start,\n    stop: genomicPos.end,\n    id: genomicPos.ensemblgene,\n    color: color\n  };\n\n  return annot;\n}\n\n/**\n * For given gene, finds and draws interacting genes and paralogs\n *\n * @param geneSymbol {String} Gene symbol, e.g. RAD51\n */\nasync function plotRelatedGenes(geneSymbol) {\n\n  const ideo = this;\n\n  ideo.annotDescriptions = {};\n\n  const ideoSel = ideo.selector;\n  const annotSel = ideoSel + ' .annot';\n  document.querySelectorAll(annotSel).forEach(el => el.remove());\n\n  ideo.startHideAnnotTooltipTimeout();\n\n  // Refine style\n  document.querySelectorAll('.chromosome').forEach(chromosome => {\n    chromosome.style.cursor = '';\n  });\n\n  const chrHeight = ideo.config.chrHeight;\n  const topPx = chrHeight + 30;\n  const leftPx =\n    Array.from(document.querySelectorAll('.chromosome-set'))\n      .slice(-1)[0].getBoundingClientRect().right;\n\n  const style =\n    `float: left; position: relative; top: -${topPx}px; left: ${leftPx}px;`;\n\n  // Fetch positon of searched gene\n  const taxid = ideo.config.taxid;\n  const queryString =\n    `?q=symbol:${geneSymbol}&species=${taxid}&fields=symbol,genomic_pos,name`;\n  const data = await fetchMyGeneInfo(queryString);\n\n  const gene = data.hits[0];\n  ideo.annotDescriptions[gene.symbol] = gene.name;\n\n  let annots = [];\n\n  const annot = parseAnnotFromMgiGene(gene, ideo);\n  annots.push(annot);\n\n  const interactions = await fetchInteractingGenes(annot, ideo);\n  const interactingAnnots =\n    await fetchInteractingGeneAnnots(interactions, ideo);\n  annots = annots.concat(interactingAnnots);\n\n  await fetchParalogPositions(annot, annots, ideo);\n\n  annots.sort((a, b) => {return b.name.length - a.name.length;});\n\n  ideo.drawAnnots(annots);\n\n  document.querySelector('#_ideogramLegend').style = style;\n}\n\n/**\n * Enhance tooltip shown on hovering over gene annotation\n */\nfunction decorateGene(annot) {\n  const ideo = this;\n  const org = ideo.getScientificName(ideo.config.taxid);\n  const term = `(${annot.name}[gene])+AND+(${org}[orgn])`;\n  const url = `https://ncbi.nlm.nih.gov/gene/?term=${term}`;\n  const description = ideo.annotDescriptions[annot.name].split(' [')[0];\n  annot.displayName =\n    `<a target=\"_blank\" href=\"${url}\">${annot.name}</a>\n    <br/>\n    ${description}\n    <br/>`;\n  return annot;\n}\n\nconst shape = 'triangle';\n\nconst legend = [{\n  name: '<b>Click gene to search</b>',\n  rows: [\n    {name: 'Interacting gene', color: 'purple', shape: shape},\n    {name: 'Paralogous gene', color: 'pink', shape: shape},\n    {name: 'Searched gene', color: 'red', shape: shape}\n  ]\n}];\n\n/**\n * Wrapper for Ideogram constructor, with generic \"Related genes\" options\n *\n * This function is made available as a static method on Ideogram.\n *\n * @param {Object} config Ideogram configuration object\n */\nfunction _initRelatedGenes(config) {\n\n  Object.assign(config, {\n    showFullyBanded: false,\n    rotatable: false,\n    legend: legend,\n    onWillShowAnnotTooltip: decorateGene\n  });\n\n  const ideogram = new Ideogram(config);\n\n  return ideogram;\n}\n\nexport {_initRelatedGenes, plotRelatedGenes};\n","/**\n * @fileoverview Core module of Ideogram.js, links all other modules\n * This file defines the Ideogram class, its constructor method, and its\n * static methods.  All instance methods are defined in other modules.\n *\n */\n\nimport version from './version';\n\nimport {\n  configure, initDrawChromosomes, handleRotateOnClick, onLoad,\n  init, finishInit, writeContainer\n} from './init/init';\n\nimport {\n  onLoadAnnots, onDrawAnnots, processAnnotData, restoreDefaultTracks,\n  updateDisplayedTracks, initAnnotSettings, fetchAnnots, drawAnnots,\n  getHistogramBars, drawHeatmaps, deserializeAnnotsForHeatmap, fillAnnots,\n  drawProcessedAnnots, drawSynteny, startHideAnnotTooltipTimeout,\n  showAnnotTooltip, onWillShowAnnotTooltip, setOriginalTrackIndexes,\n  afterRawAnnots, onClickAnnot\n} from './annotations/annotations';\n\nimport {\n  esearch, esummary, elink,\n  getOrganismFromEutils, getTaxids,\n  getAssemblyAndChromosomesFromEutils\n} from './services/services';\n\nimport {\n  drawBandLabels, getBandColorGradients, processBandData,\n  setBandsToShow, hideUnshownBandLabels, drawBandLabelText, drawBandLabelStalk\n} from './bands/bands';\n\nimport {onBrushMove, createBrush} from './brush';\nimport {onCursorMove, createClickCursor} from './cursor';\nimport {drawSexChromosomes, setSexChromosomes} from './sex-chromosomes';\nimport {convertBpToPx, convertPxToBp} from './coordinate-converters';\nimport {\n  unpackAnnots, packAnnots, initCrossFilter, filterAnnots\n} from './filter';\n\nimport {\n  assemblyIsAccession, getDataDir, round, onDidRotate, getSvg, d3,\n  getTaxid, getCommonName, getScientificName, fetch as _fetch\n} from './lib';\n\nimport {\n  getChromosomeModel, getChromosomePixels\n} from './views/chromosome-model';\n\nimport {\n  appendHomolog, drawChromosome, rotateAndToggleDisplay, setOverflowScroll\n} from './views/draw-chromosomes';\n\nimport {\n  drawChromosomeLabels, rotateChromosomeLabels\n} from './views/chromosome-labels.js';\n\nimport {_initRelatedGenes, plotRelatedGenes} from './kit/related-genes';\n\nexport default class Ideogram {\n  constructor(config) {\n\n    // Functions from init.js\n    this.configure = configure;\n    this.initDrawChromosomes = initDrawChromosomes;\n    this.onLoad = onLoad;\n    this.handleRotateOnClick = handleRotateOnClick;\n    this.init = init;\n    this.finishInit = finishInit;\n    this.writeContainer = writeContainer;\n\n    // Functions from annotations.js\n    this.onLoadAnnots = onLoadAnnots;\n    this.onDrawAnnots = onDrawAnnots;\n    this.processAnnotData = processAnnotData;\n    this.restoreDefaultTracks = restoreDefaultTracks;\n    this.updateDisplayedTracks = updateDisplayedTracks;\n    this.initAnnotSettings = initAnnotSettings;\n    this.fetchAnnots = fetchAnnots;\n    this.drawAnnots = drawAnnots;\n    this.getHistogramBars = getHistogramBars;\n    this.drawHeatmaps = drawHeatmaps;\n    this.deserializeAnnotsForHeatmap = deserializeAnnotsForHeatmap;\n    this.fillAnnots = fillAnnots;\n    this.drawProcessedAnnots = drawProcessedAnnots;\n    this.drawSynteny = drawSynteny;\n    this.startHideAnnotTooltipTimeout = startHideAnnotTooltipTimeout;\n    this.showAnnotTooltip = showAnnotTooltip;\n    this.onWillShowAnnotTooltip = onWillShowAnnotTooltip;\n    this.onClickAnnot = onClickAnnot;\n    this.setOriginalTrackIndexes = setOriginalTrackIndexes;\n    this.afterRawAnnots = afterRawAnnots;\n\n    // Variables and functions from services.js\n    this.esearch = esearch;\n    this.esummary = esummary;\n    this.elink = elink;\n    this.getOrganismFromEutils = getOrganismFromEutils;\n    this.getTaxids = getTaxids;\n    this.getAssemblyAndChromosomesFromEutils =\n      getAssemblyAndChromosomesFromEutils;\n\n    // Functions from bands.js\n    this.drawBandLabels = drawBandLabels;\n    this.getBandColorGradients = getBandColorGradients;\n    this.processBandData = processBandData;\n    this.setBandsToShow = setBandsToShow;\n    this.hideUnshownBandLabels = hideUnshownBandLabels;\n    this.drawBandLabelText = drawBandLabelText;\n    this.drawBandLabelStalk = drawBandLabelStalk;\n\n    // Functions from brush.js\n    this.onBrushMove = onBrushMove;\n    this.createBrush = createBrush;\n\n    // Functions from cursor.js\n    this.createClickCursor = createClickCursor;\n    this.onCursorMove = onCursorMove;\n\n    // Functions from sex-chromosomes.js\n    this.drawSexChromosomes = drawSexChromosomes;\n    this.setSexChromosomes = setSexChromosomes;\n\n    // Functions from coordinate-converters.js\n    this.convertBpToPx = convertBpToPx;\n    this.convertPxToBp = convertPxToBp;\n\n    // Functions from filter.js\n    this.unpackAnnots = unpackAnnots;\n    this.packAnnots = packAnnots;\n    this.initCrossFilter = initCrossFilter;\n    this.filterAnnots = filterAnnots;\n\n    // Functions from lib\n    this.assemblyIsAccession = assemblyIsAccession;\n    this.getDataDir = getDataDir;\n    this.round = round;\n    this.onDidRotate = onDidRotate;\n    this.getSvg = getSvg;\n    this.fetch = _fetch;\n    this.getTaxid = getTaxid;\n    this.getCommonName = getCommonName;\n    this.getScientificName = getScientificName;\n\n    // Functions from views/chromosome-model.js\n    this.getChromosomeModel = getChromosomeModel;\n    this.getChromosomePixels = getChromosomePixels;\n\n    // Functions from views/chromosome-labels.js\n    this.drawChromosomeLabels = drawChromosomeLabels;\n    this.rotateChromosomeLabels = rotateChromosomeLabels;\n\n    // Functions from views/draw-chromosomes.js\n    this.appendHomolog = appendHomolog;\n    this.drawChromosome = drawChromosome;\n    this.rotateAndToggleDisplay = rotateAndToggleDisplay;\n    this.setOverflowScroll = setOverflowScroll;\n\n    this.plotRelatedGenes = plotRelatedGenes;\n\n    this.configure(config);\n  }\n\n  /**\n   * Get the current version of Ideogram.js\n   */\n  static get version() {\n    return version;\n  }\n\n  /**\n  * Enable use of D3 in client apps, via \"d3 = Ideogram.d3\"\n  */\n  static get d3() {\n    return d3;\n  }\n\n  /**\n   * Request data from Ensembl REST API\n   * Docs: https://rest.ensembl.org/\n   *\n   * @param {String} path URL path\n   * @param {Object} body POST body\n   * @param {String} method HTTP method; 'GET' (default) or 'POST'\n   */\n  static async fetchEnsembl(path, body = null, method = 'GET') {\n    const init = {\n      method: method,\n      headers: {'Content-Type': 'application/json'}\n    };\n    if (body !== null) init.body = JSON.stringify(body);\n    const response = await fetch(`https://rest.ensembl.org${path}`, init);\n    const json = await response.json();\n    return json;\n  }\n\n  /**\n   * Sorts two chromosome objects by type and name\n   * - Nuclear chromosomes come before non-nuclear chromosomes.\n   * - Among nuclear chromosomes, use \"natural sorting\", e.g.\n   *   numbers come before letters\n   * - Among non-nuclear chromosomes, i.e. \"MT\" (mitochondrial DNA) and\n   *   \"CP\" (chromoplast DNA), MT comes first\n   *\n   *\n   * @param a Chromosome object \"A\"\n   * @param b Chromosome object \"B\"\n   * @returns {Number} JavaScript sort order indicator\n   */\n  static sortChromosomes(a, b) {\n    var aIsNuclear = a.type === 'nuclear',\n      bIsNuclear = b.type === 'nuclear',\n      aIsCP = a.type === 'chloroplast',\n      bIsCP = b.type === 'chloroplast',\n      aIsMT = a.type === 'mitochondrion',\n      bIsMT = b.type === 'mitochondrion',\n      aIsAP = a.type === 'apicoplast',\n      bIsAP = b.type === 'apicoplast';\n    // e.g. B1 in rice genome GCF_001433935.1\n    // aIsPlastid = aIsMT && a.name !== 'MT',\n    // bIsPlastid = bIsMT && b.name !== 'MT';\n\n    if (aIsNuclear && bIsNuclear) {\n      return a.name.localeCompare(b.name, 'en', {numeric: true});\n    } else if (!aIsNuclear && bIsNuclear) {\n      return 1;\n    } else if (aIsMT && bIsCP) {\n      return 1;\n    } else if (aIsCP && bIsMT) {\n      return -1;\n    } else if (!aIsAP && !aIsMT && !aIsCP && (bIsMT || bIsCP || bIsAP)) {\n      return -1;\n    }\n  }\n\n  /**\n   * Wrapper for Ideogram constructor, with generic \"Related genes\" options\n   *\n   * @param {Object} config Ideogram configuration object\n   */\n  static initRelatedGenes(config) {\n    return _initRelatedGenes(config);\n  }\n}\n","var version = '1.22.0';\nexport default version;\n","import Ideogram from './ideogram';\n\n// Enable references to Ideogram when loaded via traditional script tag\nwindow.Ideogram = Ideogram;\n\n// Enable references to Ideogram when imported as an ES6 module\nexport default Ideogram;\n"],"sourceRoot":""}
\ No newline at end of file
diff --git a/package-lock.json b/package-lock.json
index fbb6eb16..3c477761 100644
--- a/package-lock.json
+++ b/package-lock.json
@@ -1,6 +1,6 @@
 {
   "name": "ideogram",
-  "version": "1.21.0",
+  "version": "1.22.0",
   "lockfileVersion": 1,
   "requires": true,
   "dependencies": {
diff --git a/package.json b/package.json
index afcc8319..3a53578f 100644
--- a/package.json
+++ b/package.json
@@ -1,6 +1,6 @@
 {
   "name": "ideogram",
-  "version": "1.21.0",
+  "version": "1.22.0",
   "description": "Chromosome visualization for the web",
   "main": "src/js/index.js",
   "directories": {
diff --git a/src/js/version.js b/src/js/version.js
index 5ade91f3..21da4581 100644
--- a/src/js/version.js
+++ b/src/js/version.js
@@ -1,2 +1,2 @@
-var version = '1.21.0';
+var version = '1.22.0';
 export default version;
