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<!doctype html>
<html class="no-js" lang="en">
<head>
<meta charset="utf-8"/>
<meta name="viewport" content="width=device-width, initial-scale=1.0"/>
<meta name="description" content="Fruit Fly Brain Observatory">
<meta name="author" content="FFBO Team">
<title>Fruit Fly Brain Observatory | Welcome</title>
<!-- Bootstrap Core CSS -->
<link href="css/bootstrap.min.css" rel="stylesheet">
<link href="css/ffbo.css" rel="stylesheet">
<link rel="shortcut icon" href="ico/favicon.ico" />
</head>
<body>
<!-- PRELOADING -->
<div id="preload">
<div class="preload">
<div class="loader">
</div>
<h2>loading ...</h2>
</div>
</div>
<!-- Navigation -->
<nav class="navbar navbar-fixed-top navbar-ffbo" role="navigation">
<div class="container">
<div data-scroll-header class="navbar-header">
<button type="button" class="navbar-toggle" data-toggle="collapse" data-target="#nav">
<span class="sr-only">Toggle navigation</span>
<span class="icon-bar"></span>
<span class="icon-bar"></span>
<span class="icon-bar"></span>
</button>
<a class="navbar-brand" href="index.html"><span><img width="50px" height="50px" src="img/ffbo_logo.png"></span> Fruit Fly Brain Observatory</a>
</div>
<div class="collapse navbar-collapse" id="nav">
<ul class="nav navbar-nav navbar-right uppercase">
<li><a data-scroll href="#about">About</a></li>
<li><a data-scroll href="#team">Team</a></li>
<li><a data-scroll href="#tech">Technology</a></li>
<li><a data-scroll href="#workflow">Workflow</a></li>
</ul>
</div>
<!-- /.navbar-collapse -->
</div>
<!-- /.container -->
</nav>
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<section id="banner" data-stellar-background-ratio="0.5">
<div class="countdown">
<div class="container">
<div class="row">
<div class="col-lg-8 col-lg-offset-2 text-center">
<h1>Fruit Fly Brain Observatory</h1>
</div>
</div>
</div>
</div>
</section>
<!-- carousel -->
<section id="carousel" data-stellar-background-ratio="0.5">
<div class="row">
<div class="col-lg-12">
<div id="carousel-outer" class="carousel slide" data-ride="carousel" data-interval="4000">
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<ol class="carousel-indicators">
<li data-target="#carousel-outer" data-slide-to="0" class="active"></li>
<li data-target="#carousel-outer" data-slide-to="1"></li>
</ol>
<!-- Wrapper for slides -->
<div class="carousel-inner" role="listbox">
<div class="item active">
<img src="img/osp.png" alt="osp">
<div class="carousel-caption">
<h2>FFBO is One of the 6 Open Science Prize Finalists</h2>
<a href="https://goo.gl/NXQ8jp" role="button" class="btn btn-primary">Read NIH Press Release</a>
<a href="https://goo.gl/NXQ8jp" role="button" class="btn btn-info">Read NIH Input|Output Blog Post</a>
<p></p>
</div>
</div>
<div class="item">
<img src="img/data_model.png" alt="data_model">
<div class="carousel-caption">
<h2>RFC for NeuroArch is Available</h2>
<a href="http://neurokernel.github.io/docs.html" role="button" class="btn btn-success">Take Me to the RFC</a>
<p></p>
</div>
</div>
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<a class="left carousel-control" href="#carousel-outer" role="button" data-slide="prev">
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</div>
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</div>
</section>
<!-- mission -->
<section id="mission">
<div class="row">
<div class="col-lg-4 col-lg-push-4 text-centered">
<h2>Our Mission<a name="about"></a></h2>
<p style=text-align:justify;">
We propose to develop an open graph database platform called NeuroArch to store
and process all connected data related to the neural circuits of the fly brain
including location, morphology, connectivity and biophysical properties of
every neuron of the adult fruit fly brain. This will enable the automatic
generation of alternative models of the fly brain that can be simulated
efficiently using multiple Graphics Processing Units in order to help elucidate
the mechanisms of human neurological disorders and to help identify drug
targets.
</p>
</div>
<div class="col-lg-4 col-lg-pull-4 text-centered" style="background:#000000">
<video id="medulla-vid" loop preload width="90%">
<source src="video/medulla360.mp4" type="video/mp4">
</video>
<h5>3D Vision Circuit</h5>
</div>
<div class="col-lg-4 text-centered" style="background:#000000">
<video id="whole-brain-vid" loop preload width="90%">
<source src="video/brain360.mp4" type="video/mp4">
</video>
<h5>3D Whole Brain</h5>
</div>
</div>
</section>
<section id="team">
<h2 align="center">Fruit Fly Brain Explorers<a name="team"></a></h2>
<div class="row">
<div class="col-md-4">
<p><img src="img/columbia.svg"/></p>
<h4 align="center"><a href="http://www.bionet.ee.columbia.edu">Bionet Group</a></h4>
<p style=text-align:justify;">
Located at Columbia University's Department of Electrical Engineering, the
Bionet Group is an interdisciplinary research team bringing together faculty
and students from the biological and engineering sciences focusing on
understanding the function of neural circuits, and the architecture of the
fruit fly (Drosophila melanogaster) brain.</p>
</div>
<div class="col-md-4">
<p><img src="img/sheffield.png"/></p>
<h5 align="center"><a href="https://www.sheffield.ac.uk/acse/spcs">Centre for Signal Processing and Complex Systems</a></h5>
<p style=text-align:justify;">
Located at the University of Sheffield's Department of Department of
Automatic Control and Systems Engineering, the Group is an
interdisciplinary research team of Engineers and Computer Scientists.
We utilize a systems engineering approach to better understand the
computation and function of the Drosophila melongaster visual system.</p>
</div>
<div class="col-md-4">
<p><img src="img/nthu.svg"/></p>
<h4 align="center"><a href="http://life.nthu.edu.tw/~lablcc/">Brain Research Center</a></h4>
<p style=text-align:justify;">
Located at National Tsing Hua University, Taiwan, the Brain Research Center focuses on neural circuit
mechanisms of cognitive behavior and physiological functions. The works of
the lab emphasize simulating large scale neural networks using spiking
neural modeling and constructing models based on experimental observations
covering from.</p>
</div>
</div>
<!-- /.row -->
</div>
<section id="tech">
<h2>Technology<a name="tech"></a></h2>
<br>
<div class="row">
<div class="col-lg-4 col-lg-offset-2 col-md-6">
<p><img src="img/biological_data.png"/></p>
</div>
<div class="col-lg-4 col-md-6">
<h4><a href="http://www.flycircuit.tw/">Biological Data</a></h4>
<p style="text-align:justify">
The fruit fly brain has ~150,000 neurons. Highly detailed open dataset
FlyCircuit at single neuron resolution, along with other open databases
of the fly brain provides increasing accessible data to study brain
function and neurological disease.
</p>
</div>
<!-- /.row -->
</div>
<br>
<div class="row">
<div class="col-lg-4 col-lg-push-4 col-lg-offset-2 col-md-6 col-md-push-6">
<p><img src="img/neuroarch.png"/></p>
</div>
<div class="col-lg-4 col-lg-pull-4 col-md-6 col-md-pull-6">
<h4><a href="http://neurokernel.github.io/docs.html">NeuroArch</a></h4>
<p style="text-align:justify">
NeuroArch will become an open graph database that exposes the extensive
neurobiological data associated with pathologies of interest and provide
the programming services (APIs) needed to algorithmically construct
executable models.
</p>
</div>
<!-- /.row -->
</div>
<br>
<div class="row">
<div class="col-lg-4 col-lg-offset-2 col-md-6">
<p><img src="https://neurokernel.github.io/img/fly.png"/></p>
</div>
<div class="col-lg-4 col-md-6">
<h4><a href="https://neurokernel.github.io">Neurokernel</a></h4>
<p style="text-align:justify">
Neurokernel is an open source platform for emulating the fruit fly
brain. It provides an programming interface for efficiently executing
modular fly brain models on a cluster of Graphics Processing Units (GPUs).
</p>
</div>
<!-- /.row -->
</div>
</section>
<!-- /.section -->
<section id="workflow">
<h2>Workflow<a name="workflow"></a></h2>
<div class="row">
<div class="col-lg-5 col-lg-offset-2">
<p><img src="img/workflow.png"/></p>
</div>
<div class="col-lg-3">
<p style="text-align:justify; padding-top: 10px;">
NeuroArch enables researchers to utilize open fly brain datasets to
design executable circuit models that can be evaluated with Neurokernel.
Deviations in evaluation results can be used to refine stored models.
</p>
</div>
<!-- /.row -->
</div>
</section>
<!-- /.section -->
<footer class="footer">
<div class="row">
<p>Copyright © 2016 FFBO. All Rights Reserved.</p>
</div>
</footer>
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