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kinotypeClusteringAndRegression

Joint Repository of GR Metrics Regression and Kinase Interaction Network (KIN) Clustering

subnetGRcurves

Growth Response curve prediction leveraging cell line, KIN, subnetwork, and other datasets

GR50, a measure of potency, is the concentration of drug that reduces cell proliferation rate by one-half;
GRmax, a measure of efficacy, is the maximum effect of a drug at the highest tested concentration; and
GRAOC combines these in an integrated ‘area over the curve’ value.