@@ -133,11 +133,43 @@ This is a bugfix release. It fixes the following problem(s):
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resulting in the observed behavior. This release reverts the change from PR
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988.
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- This is a bugfix release. It fixes the following problem(s):
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-
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Version 4.0.6
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-------------
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+ This is a bugfix release. It fixes the following problem(s):
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+
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- A bug in the aggregate report creation incorrectly evaluated the Transcript
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Support Level and resulted in picking the wrong Best Transcript in some
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cases.
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+
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+ Version 4.0.7
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+ -------------
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+
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+ This is a bugfix release. It fixes the following problem(s):
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+
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+ - The multithreading capabilities in pVACtools are not available for Mac OSX.
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+ Attempting to use the -t parameter would result in the forked processes
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+ crashing but the run would still complete successfully leading to results
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+ with incomplete data. This release will result in an error when multithreading is
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+ used under Mac OSX.
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+ - We've observed issues with IEDB's API sometimes returning incorrect or
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+ incomplete data. This results in downstream errors. This release updates the prediction
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+ calling to log such occurrences and to retry the API when they are observed.
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+ - MHCflurry sometimes returns no binding affinity percentile data. This
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+ resulted in errors when parsing such prediction data. This release fixes our
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+ parsing logic to handle this case.
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+ - TSL parsing of the input VCF in pVACseq used to be limited to human data
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+ only. This release adds support for TSL parsing in mouse data.
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+ - When running with the --noncanonical flag, the exons.csv file will contain
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+ exon postions for all possible transcript combinations. However, the transcripts
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+ weren't being taken into account when parsing this file to determine the fusion
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+ positions. This release fixes this issue by looking up the positions for the
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+ specific transcripts of the record currently being parsed.
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+ - When using BLASTp for the reference proteome match step, we applied the word-size
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+ parameter in order to only return perfect matches. However, for short sequences,
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+ word-size must be less than half the query length, or reliable hits can be missed.
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+ This release updates how the word-size parameter is calculated in order to
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+ meet this criteria.
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+ - This release addresses in error in pVACview that would occur in the
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+ Transcripts in Set window when there are
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+ no peptides passing the aggregate inclusion binding threshold.
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