The HADDOCK3 software is provided "as is" and without warranties. The authors of the software will not be held liable for any use of the HADDOCK3 package and derivatives/results.
Some of HADDOCK3 modules use the CNS software (http://cns-online.org/v1.3/) (Crystallography and NMR System) as computational engine.
While CNS is free of use for non-profit users, a proper license is required for commercial applications. Biovia is handling those licenses (https://www.3ds.com/how-to-buy/contact-sales). While they officially do not distribute CNS (CNX) anymore, they usually allow the use of the non-profit version provided a proper license is purchased for some of their modelling software.
The HADDOCK3 modules using CNS are:
-
topology modules:
- topoaa
- topocg
-
sampling modules:
- rigidbody
-
refinement modules:
- flexref
- emref
- mdref
-
scoring modules:
- emscoring
- mdscoring
-
analysis modules:
- alascan
Commercial use of any of the above-mentioned modules in a HADDOCK3 workflow will thus require a proper CNS license. It is your responsibility as a user to make sure you have such a license.