diff --git a/depends/README.md b/depends/README.md
index a8dfc83e3bb54..37b2547ea7560 100644
--- a/depends/README.md
+++ b/depends/README.md
@@ -87,7 +87,7 @@ For linux S390X cross compilation:
 
 ### Install the required dependencies: OpenBSD
 
-    pkg_add bash gtar
+    pkg_add bash gmake gtar
 
 ### Dependency Options
 
diff --git a/doc/build-openbsd.md b/doc/build-openbsd.md
index 7ed83853a8673..463d4101194c5 100644
--- a/doc/build-openbsd.md
+++ b/doc/build-openbsd.md
@@ -1,6 +1,6 @@
 # OpenBSD Build Guide
 
-**Updated for OpenBSD [7.4](https://www.openbsd.org/74.html)**
+**Updated for OpenBSD [7.5](https://www.openbsd.org/75.html)**
 
 This guide describes how to build bitcoind, command-line utilities, and GUI on OpenBSD.
 
@@ -10,9 +10,7 @@ This guide describes how to build bitcoind, command-line utilities, and GUI on O
 Run the following as root to install the base dependencies for building.
 
 ```bash
-pkg_add bash git gmake libevent libtool boost
-# Select the newest version of the following packages:
-pkg_add autoconf automake python
+pkg_add git cmake boost libevent
 ```
 
 See [dependencies.md](dependencies.md) for a complete overview.
@@ -31,7 +29,7 @@ It is not necessary to build wallet functionality to run either `bitcoind` or `b
 
 ###### Descriptor Wallet Support
 
-`sqlite3` is required to support [descriptor wallets](descriptors.md).
+SQLite is required to support [descriptor wallets](descriptors.md).
 
 ``` bash
 pkg_add sqlite3
@@ -48,13 +46,13 @@ Refer to [depends/README.md](/depends/README.md) for detailed instructions.
 ```bash
 gmake -C depends NO_BOOST=1 NO_LIBEVENT=1 NO_QT=1 NO_SQLITE=1 NO_NATPMP=1 NO_UPNP=1 NO_ZMQ=1 NO_USDT=1
 ...
-to: /path/to/bitcoin/depends/x86_64-unknown-openbsd
+to: /path/to/bitcoin/depends/*-unknown-openbsd*
 ```
 
 Then set `BDB_PREFIX`:
 
 ```bash
-export BDB_PREFIX="/path/to/bitcoin/depends/x86_64-unknown-openbsd"
+export BDB_PREFIX="[path displayed above]"
 ```
 
 #### GUI Dependencies
@@ -63,50 +61,44 @@ export BDB_PREFIX="/path/to/bitcoin/depends/x86_64-unknown-openbsd"
 Bitcoin Core includes a GUI built with the cross-platform Qt Framework. To compile the GUI, Qt 5 is required.
 
 ```bash
-pkg_add qt5
+pkg_add qtbase qttools
 ```
 
-## Building Bitcoin Core
-
-**Important**: Use `gmake` (the non-GNU `make` will exit with an error).
+#### Test Suite Dependencies
+There is an included test suite that is useful for testing code changes when developing.
+To run the test suite (recommended), you will need to have Python 3 installed:
 
-Preparation:
 ```bash
-
-# Adapt the following for the version you installed (major.minor only):
-export AUTOCONF_VERSION=2.71
-export AUTOMAKE_VERSION=1.16
-
-./autogen.sh
+pkg_add install python  # Select the newest version of the package.
 ```
 
+## Building Bitcoin Core
+
 ### 1. Configuration
 
 There are many ways to configure Bitcoin Core, here are a few common examples:
 
 ##### Descriptor Wallet and GUI:
-This enables the GUI and descriptor wallet support, assuming `sqlite` and `qt5` are installed.
+This enables the GUI and descriptor wallet support, assuming SQLite and Qt 5 are installed.
 
 ```bash
-./configure MAKE=gmake
+cmake -B build -DWITH_SQLITE=ON -DWITH_GUI=Qt5
 ```
 
+Run `cmake -B build -LH` to see the full list of available options.
+
 ##### Descriptor & Legacy Wallet. No GUI:
 This enables support for both wallet types and disables the GUI:
 
 ```bash
-./configure --with-gui=no \
-    BDB_LIBS="-L${BDB_PREFIX}/lib -ldb_cxx-4.8" \
-    BDB_CFLAGS="-I${BDB_PREFIX}/include" \
-    MAKE=gmake
+cmake -B build -DWITH_GUI=OFF -DBerkeleyDB_INCLUDE_DIR:PATH="${BDB_PREFIX}/include"
 ```
 
 ### 2. Compile
-**Important**: Use `gmake` (the non-GNU `make` will exit with an error).
 
 ```bash
-gmake # use "-j N" for N parallel jobs
-gmake check # Run tests if Python 3 is available
+cmake --build build     # Use "-j N" for N parallel jobs.
+ctest --test-dir build  # Use "-j N" for N parallel tests. Some tests are disabled if Python 3 is not available.
 ```
 
 ## Resource limits