diff --git a/optimum/intel/openvino/modeling_base.py b/optimum/intel/openvino/modeling_base.py
index cb103bb35a..eb1ed88467 100644
--- a/optimum/intel/openvino/modeling_base.py
+++ b/optimum/intel/openvino/modeling_base.py
@@ -339,7 +339,7 @@ def compile(self):
         if self.request is None:
             logger.info(f"Compiling the model to {self._device} ...")
             ov_config = {**self.ov_config}
-            if "CACHE_DIR" not in self.ov_config.keys() and not self.model_save_dir.is_relative_to(gettempdir()):
+            if "CACHE_DIR" not in self.ov_config.keys() and not str(self.model_save_dir).startswith(gettempdir()):
                 # Set default CACHE_DIR only if it is not set, and if the model is not in a temporary directory
                 cache_dir = Path(self.model_save_dir).joinpath("model_cache")
                 ov_config["CACHE_DIR"] = str(cache_dir)
diff --git a/optimum/intel/openvino/modeling_diffusion.py b/optimum/intel/openvino/modeling_diffusion.py
index c88b61e58a..2707260606 100644
--- a/optimum/intel/openvino/modeling_diffusion.py
+++ b/optimum/intel/openvino/modeling_diffusion.py
@@ -539,7 +539,7 @@ def __init__(
         self._model_dir = Path(model_dir or parent_model._model_save_dir)
         config_path = self._model_dir / model_name / self.CONFIG_NAME
         self.config = self.parent_model._dict_from_json_file(config_path) if config_path.is_file() else {}
-        if "CACHE_DIR" not in self.ov_config.keys() and not self._model_dir.is_relative_to(gettempdir()):
+        if "CACHE_DIR" not in self.ov_config.keys() and not str(self._model_dir).startswith(gettempdir()):
             self.ov_config["CACHE_DIR"] = os.path.join(self._model_dir, self._model_name, "model_cache")
 
     def _compile(self):
diff --git a/optimum/intel/openvino/modeling_seq2seq.py b/optimum/intel/openvino/modeling_seq2seq.py
index f2e2a989b7..c800312e82 100644
--- a/optimum/intel/openvino/modeling_seq2seq.py
+++ b/optimum/intel/openvino/modeling_seq2seq.py
@@ -205,7 +205,7 @@ def __init__(
         encoder_cache_dir = Path(self.model_save_dir).joinpath("encoder_cache")
         ov_encoder_config = self.ov_config
 
-        if "CACHE_DIR" not in ov_encoder_config.keys() and not self.model_save_dir.is_relative_to(gettempdir()):
+        if "CACHE_DIR" not in ov_encoder_config.keys() and not str(self.model_save_dir).startswith(gettempdir()):
             ov_encoder_config["CACHE_DIR"] = str(encoder_cache_dir)
 
         self.encoder = OVEncoder(
@@ -215,7 +215,7 @@ def __init__(
         decoder_cache_dir = Path(self.model_save_dir).joinpath("decoder_cache")
         ov_decoder_config = self.ov_config
 
-        if "CACHE_DIR" not in ov_decoder_config.keys() and not self.model_save_dir.is_relative_to(gettempdir()):
+        if "CACHE_DIR" not in ov_decoder_config.keys() and not str(self.model_save_dir).startswith(gettempdir()):
             ov_decoder_config["CACHE_DIR"] = str(decoder_cache_dir)
 
         self.decoder = OVDecoder(self.decoder_model, self._device, ov_decoder_config)
@@ -224,7 +224,7 @@ def __init__(
             decoder_past_cache_dir = Path(self.model_save_dir).joinpath("decoder_past_cache")
             ov_decoder_past_config = self.ov_config
 
-            if "CACHE_DIR" not in ov_decoder_past_config.keys() and not self.model_save_dir.is_relative_to(
+            if "CACHE_DIR" not in ov_decoder_past_config.keys() and not str(self.model_save_dir).startswith(
                 gettempdir()
             ):
                 ov_decoder_past_config["CACHE_DIR"] = str(decoder_past_cache_dir)