diff --git a/README.md b/README.md index b80b4ce..1b5eebf 100644 --- a/README.md +++ b/README.md @@ -4,6 +4,20 @@ [![CRAN Downloads](https://cranlogs.r-pkg.org/badges/DRomics)](https://cran.r-project.org/package=DRomics) [![R-CMD-check](https://github.com/lbbe-software/DRomics/workflows/R-CMD-check/badge.svg)](https://github.com/lbbe-software/DRomics/actions) +--------------------------- + +**Please note! Since June 2024, this repository has belonged to the *lbbe-software* organization.** +To avoid confusion, we strongly recommend updating any existing local clones to point to the new +repository URL. You can do this by using `git remote` on the command line: + +`git remote set-url origin git@github.com:lbbe-software/DRomics.git` + +or + +`git remote set-url origin https://github.com/lbbe-software/DRomics.git` + +--------------------------- + `DRomics` is a freely available tool for dose-response (or concentration-response) characterization from omics data. It is especially dedicated to omics data obtained using a typical dose-response design, favoring a great number of tested doses (or concentrations) rather than a great number of replicates (no need of replicates to use `DRomics`). After a first step which consists in importing, checking and if needed normalizing/transforming the data (step 1), the aim of the proposed workflow is to select monotonic and/or biphasic significantly responsive items (e.g. probes, contigs, metabolites) (step 2), to choose the best-fit model among a predefined family of monotonic and biphasic models to describe the response of each selected item (step 3), and to derive a benchmark dose or concentration from each fitted curve (step 4). Those steps can be performed in R using `DRomics` functions, or using the shiny application named `DRomics-shiny`.