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<!DOCTYPE html>
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<head>
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<title>Leandro Tiburske</title>
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<a href="#About">About</a>
<a href="#Experience">Experience</a>
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<h1>Leandro Tiburske</h1>
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</section>
<section id="About">
<div class="container about-background">
<hr>
<h2 id="about-title">About</h2>
<div id="about-text-container">
<img src="./img/78895.jpeg" height="400" id="boat-picture">
<p>I am a <span>Bioinformatician</span> proficient in <span>Python, R and Bash</span> programming with hands-on experience
in pipeline orchestration with <span>Nextflow</span>, high-performance computing (<span>HPC</span>) and development of Next-Generation Sequencing (<span>NGS</span>)
data analysis pipelines. A curious, logical, and organised professional, I am proactive, quick to learn, and adept at <span>problem-solving</span>.
</p>
<p>I am dedicated to using data to uncover valuable insights that push biological research and innovation forward!</p>
</div>
</div>
</section>
<section id="Experience" style="clear: right;">
<div class="container experience-background">
<hr>
<h2 id="portfolio-title">Experience</h2>
<section class="py-5">
<ul class="timeline-with-icons">
<li class="timeline-item mb-5">
<span class="timeline-icon">
<svg xmlns="http://www.w3.org/2000/svg" width="25" height="16" fill="black" class="bi bi-cpu-fill" viewBox="0 0 16 16">
<path d="M6.5 6a.5.5 0 0 0-.5.5v3a.5.5 0 0 0 .5.5h3a.5.5 0 0 0 .5-.5v-3a.5.5 0 0 0-.5-.5z"/>
<path d="M5.5.5a.5.5 0 0 0-1 0V2A2.5 2.5 0 0 0 2 4.5H.5a.5.5 0 0 0 0 1H2v1H.5a.5.5 0 0 0 0 1H2v1H.5a.5.5 0 0 0 0 1H2v1H.5a.5.5 0 0 0 0 1H2A2.5 2.5 0 0 0 4.5 14v1.5a.5.5 0 0 0 1 0V14h1v1.5a.5.5 0 0 0 1 0V14h1v1.5a.5.5 0 0 0 1 0V14h1v1.5a.5.5 0 0 0 1 0V14a2.5 2.5 0 0 0 2.5-2.5h1.5a.5.5 0 0 0 0-1H14v-1h1.5a.5.5 0 0 0 0-1H14v-1h1.5a.5.5 0 0 0 0-1H14v-1h1.5a.5.5 0 0 0 0-1H14A2.5 2.5 0 0 0 11.5 2V.5a.5.5 0 0 0-1 0V2h-1V.5a.5.5 0 0 0-1 0V2h-1V.5a.5.5 0 0 0-1 0V2h-1zm1 4.5h3A1.5 1.5 0 0 1 11 6.5v3A1.5 1.5 0 0 1 9.5 11h-3A1.5 1.5 0 0 1 5 9.5v-3A1.5 1.5 0 0 1 6.5 5"/>
</svg>
</span>
<h5 class="role fw-bold"><span>Bioinformatics Analyst</span> - <a target="_blank" href="https://biotrop.com/">BIOTROP</a></h5>
<p class="text-muted mb-2 fw-bold">April 2024 - Present</p>
<p class="text-muted">
Responsible for analysing metagenomics sequencing data to produce reports that facilitate data-driven sales of biological inputs,
as well as improving and developing NGS data analysis pipelines.
</p>
</li>
<li class="timeline-item mb-5">
<span class="timeline-icon">
<svg xmlns="http://www.w3.org/2000/svg" width="25" height="16" fill="black" class="bi bi-cpu-fill" viewBox="0 0 16 16">
<path d="M6.5 6a.5.5 0 0 0-.5.5v3a.5.5 0 0 0 .5.5h3a.5.5 0 0 0 .5-.5v-3a.5.5 0 0 0-.5-.5z"/>
<path d="M5.5.5a.5.5 0 0 0-1 0V2A2.5 2.5 0 0 0 2 4.5H.5a.5.5 0 0 0 0 1H2v1H.5a.5.5 0 0 0 0 1H2v1H.5a.5.5 0 0 0 0 1H2v1H.5a.5.5 0 0 0 0 1H2A2.5 2.5 0 0 0 4.5 14v1.5a.5.5 0 0 0 1 0V14h1v1.5a.5.5 0 0 0 1 0V14h1v1.5a.5.5 0 0 0 1 0V14h1v1.5a.5.5 0 0 0 1 0V14a2.5 2.5 0 0 0 2.5-2.5h1.5a.5.5 0 0 0 0-1H14v-1h1.5a.5.5 0 0 0 0-1H14v-1h1.5a.5.5 0 0 0 0-1H14v-1h1.5a.5.5 0 0 0 0-1H14A2.5 2.5 0 0 0 11.5 2V.5a.5.5 0 0 0-1 0V2h-1V.5a.5.5 0 0 0-1 0V2h-1V.5a.5.5 0 0 0-1 0V2h-1zm1 4.5h3A1.5 1.5 0 0 1 11 6.5v3A1.5 1.5 0 0 1 9.5 11h-3A1.5 1.5 0 0 1 5 9.5v-3A1.5 1.5 0 0 1 6.5 5"/>
</svg> </span>
<h5 class="role fw-bold"><span>Research Intern</span> - <a target="_blank" href="https://liu.se/en">Linköping University</a></h5>
<p class="text-muted mb-2 fw-bold">August 2023 - November 2023</p>
<p class="text-muted">
Orchestrated a Bash pipeline on a HPC to preprocess and analyse raw metagenomics data.
Assisted in organising and preparing samples for sequencing in partnership with SciLifeLab, the Swedish Institute of biological high-throughput data.
</p>
</li>
<li class="timeline-item mb-5">
<span class="timeline-icon">
<svg xmlns="http://www.w3.org/2000/svg" width="25" height="16" fill="black" class="bi bi-cpu-fill" viewBox="0 0 16 16">
<path d="M6.5 6a.5.5 0 0 0-.5.5v3a.5.5 0 0 0 .5.5h3a.5.5 0 0 0 .5-.5v-3a.5.5 0 0 0-.5-.5z"/>
<path d="M5.5.5a.5.5 0 0 0-1 0V2A2.5 2.5 0 0 0 2 4.5H.5a.5.5 0 0 0 0 1H2v1H.5a.5.5 0 0 0 0 1H2v1H.5a.5.5 0 0 0 0 1H2v1H.5a.5.5 0 0 0 0 1H2A2.5 2.5 0 0 0 4.5 14v1.5a.5.5 0 0 0 1 0V14h1v1.5a.5.5 0 0 0 1 0V14h1v1.5a.5.5 0 0 0 1 0V14h1v1.5a.5.5 0 0 0 1 0V14a2.5 2.5 0 0 0 2.5-2.5h1.5a.5.5 0 0 0 0-1H14v-1h1.5a.5.5 0 0 0 0-1H14v-1h1.5a.5.5 0 0 0 0-1H14v-1h1.5a.5.5 0 0 0 0-1H14A2.5 2.5 0 0 0 11.5 2V.5a.5.5 0 0 0-1 0V2h-1V.5a.5.5 0 0 0-1 0V2h-1V.5a.5.5 0 0 0-1 0V2h-1zm1 4.5h3A1.5 1.5 0 0 1 11 6.5v3A1.5 1.5 0 0 1 9.5 11h-3A1.5 1.5 0 0 1 5 9.5v-3A1.5 1.5 0 0 1 6.5 5"/>
</svg> </span>
<h5 class="role fw-bold"> <span>Undergraduate Researcher</span> - <a target="_blank" href="https://www.einstein.br/en/Pages/Home.aspx">Albert Einstein Education and Research Center</a></h5>
<p class="text-muted mb-2 fw-bold">September 2022 - March 2024</p>
<p class="text-muted">
Conducted a comprehensive analysis of single-nuclei and bulk RNA-Seq data from brain samples of individuals with bipolar disorder.
Identified a potential role for the genes <span>CHI3L1</span> and <span>SERPINA3</span> in the neuroinflammatory and neurodegenerative processes associated with bipolar disorder.
</p>
</li>
</div>
</section>
</section>
<section id="Education">
<div class="container experience-background">
<hr>
<h2 id="portfolio-title">Education</h2>
<section class="py-5">
<ul class="timeline-with-icons">
<li class="timeline-item mb-5">
<span class="timeline-icon">
<svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 448 512"><path d="M416 0c17.7 0 32 14.3 32 32c0 59.8-30.3 107.5-69.4 146.6c-28 28-62.5 53.5-97.3 77.4l-2.5 1.7c-11.9 8.1-23.8 16.1-35.5 23.9c0 0 0 0 0 0s0 0 0 0s0 0 0 0l-1.6 1c-6 4-11.9 7.9-17.8 11.9c-20.9 14-40.8 27.7-59.3 41.5l118.5 0c-9.8-7.4-20.1-14.7-30.7-22.1l7-4.7 3-2c15.1-10.1 30.9-20.6 46.7-31.6c25 18.1 48.9 37.3 69.4 57.7C417.7 372.5 448 420.2 448 480c0 17.7-14.3 32-32 32s-32-14.3-32-32L64 480c0 17.7-14.3 32-32 32s-32-14.3-32-32c0-59.8 30.3-107.5 69.4-146.6c28-28 62.5-53.5 97.3-77.4c-34.8-23.9-69.3-49.3-97.3-77.4C30.3 139.5 0 91.8 0 32C0 14.3 14.3 0 32 0S64 14.3 64 32l320 0c0-17.7 14.3-32 32-32zM338.6 384l-229.2 0c-10.1 10.6-18.6 21.3-25.5 32l280.2 0c-6.8-10.7-15.3-21.4-25.5-32zM109.4 128l229.2 0c10.1-10.7 18.6-21.3 25.5-32L83.9 96c6.8 10.7 15.3 21.3 25.5 32zm55.4 48c18.4 13.8 38.4 27.5 59.3 41.5c20.9-14 40.8-27.7 59.3-41.5l-118.5 0z"/></svg>
</span>
<h5 class="role fw-bold">MBA in <span> Software Engineering</span> - University of São Paulo</h5>
<p class="text-muted mb-2 fw-bold">October 2024 - Present</p>
<p class="text-muted">
Focus on software development, DevOps, cloud computing, and infrastructure as code.
Covers agile methodologies, UX, data engineering, machine learning, big data, blockchain, and API management, while developing leadership and emotional intelligence skills.
</p>
</li>
<li class="timeline-item mb-5">
<span class="timeline-icon">
<svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 448 512"><path d="M416 0c17.7 0 32 14.3 32 32c0 59.8-30.3 107.5-69.4 146.6c-28 28-62.5 53.5-97.3 77.4l-2.5 1.7c-11.9 8.1-23.8 16.1-35.5 23.9c0 0 0 0 0 0s0 0 0 0s0 0 0 0l-1.6 1c-6 4-11.9 7.9-17.8 11.9c-20.9 14-40.8 27.7-59.3 41.5l118.5 0c-9.8-7.4-20.1-14.7-30.7-22.1l7-4.7 3-2c15.1-10.1 30.9-20.6 46.7-31.6c25 18.1 48.9 37.3 69.4 57.7C417.7 372.5 448 420.2 448 480c0 17.7-14.3 32-32 32s-32-14.3-32-32L64 480c0 17.7-14.3 32-32 32s-32-14.3-32-32c0-59.8 30.3-107.5 69.4-146.6c28-28 62.5-53.5 97.3-77.4c-34.8-23.9-69.3-49.3-97.3-77.4C30.3 139.5 0 91.8 0 32C0 14.3 14.3 0 32 0S64 14.3 64 32l320 0c0-17.7 14.3-32 32-32zM338.6 384l-229.2 0c-10.1 10.6-18.6 21.3-25.5 32l280.2 0c-6.8-10.7-15.3-21.4-25.5-32zM109.4 128l229.2 0c10.1-10.7 18.6-21.3 25.5-32L83.9 96c6.8 10.7 15.3 21.3 25.5 32zm55.4 48c18.4 13.8 38.4 27.5 59.3 41.5c20.9-14 40.8-27.7 59.3-41.5l-118.5 0z"/></svg>
</span>
<h5 class="role fw-bold">BSc in <span>Biomedical Sciences</span> - University of São Paulo</h5>
<p class="text-muted mb-2 fw-bold">January 2020 - March 2024</p>
<p class="text-muted">
Attended classes at both undergraduate and graduate levels:<br>
<span>Differential and Integral Calculus (Mathematics Undergraduate Program),
Systems Biology (Bioinformatics Graduate Program),
Microbiome Data analysis (Pharmaceutical Sciences Graduate Program),
Concepts of Programming Languages (Computer Science Graduate Program).
</span>
</p>
</li>
</div>
</section>
</section>
<section id="Skills">
<div class="container skills-background">
<hr>
<h2 id="skills-title">Skills</h2>
<div class="container skills-list">
<hr>
<h3>Programming languages</h3>
<div id="programming-languages" class="skill-section">
<div>
<img src="./img/Python-logo-notext.svg.png">
<p>Python</p>
</div>
<div>
<img src="./img/R_logo.svg.png">
<p>R</p>
</div>
<div>
<img src="./img/Bash_Logo_black_and_white_icon_only.svg.png">
<p>Bash</p>
</div>
<div>
<img src="./img/rust.png">
<p>Rust</p>
</div>
</div>
<hr>
<h3>Workflow orchestration</h3>
<div id="pipeline-orchestration" class="skill-section">
<div>
<img src="./img/nflogo.png">
<p>Nextflow</p>
</div>
</div>
<hr>
<h3>Front-end development</h3>
<div id="front-end" class="skill-section">
<div>
<img src="./img/HTML5_Badge.svg.png">
<p>HTML</p>
</div>
<div>
<img src="./img/CSS3_logo.svg">
<p>CSS</p>
</div>
<div>
<img src="./img/Bootstrap_logo.svg.png">
<p>Bootstrap</p>
</div>
</div>
<hr>
<h3>Other technologies</h3>
<div id="other-technologies" class="skill-section">
<div>
<img src="./img/dna-icon.svg">
<p>NGS data analysis</p>
</div>
<div>
<img src="./img/6698688.png">
<p>Docker</p>
</div>
<div>
<img src="./img/github.svg">
<p>Version control</p>
</div>
<div>
<img src="./img/azure.png">
<p>Azure</p>
</div>
</div>
<div>
</div>
</div>
</section>
<section id="Portfolio">
<div class="container portfolio-background">
<hr>
<h2 id="portfolio-title">Portfolio</h2>
<div class= "grid-portfolio container">
<div class="container repo">
<img src="./img/dag-20240924-33469667.png">
<h3>scMultiAnnotator</h3>
<div class="container technologies-portfolio">
<img src="./img/Python-logo-notext.svg.png" title="Python">
<img src="./img/Bash_Logo_black_and_white_icon_only.svg.png" title="Bash">
<img src="./img/nflogo.png" title="Nextflow">
<img src="./img/6698688.png" title="Docker">
</div>
<p>scMultiAnnotator facilitates single-cell annotation according to its gold standards. This Nextflow-orchestrated pipeline implements three annotation algorithms, each using a different approach.</p>
<br>
<div class="open-on-github">
<a href="https://github.com/leandrotiburske/scMultiAnnotator" target="_blank" >
<p>Open on GitHub</p>
</a>
<a href="https://github.com/leandrotiburske/scMultiAnnotator" target="_blank">
<img src="./img/github.svg" height="25px">
</a>
</div>
</div>
<div class="container repo">
<img src="./img/network.png">
<h3>bionet-rs</h3>
<div class="container technologies-portfolio">
<img src="./img/rust.png" title="Rust">
</div>
<p>Rust implementation of gene coexpression networks for efficient and fast analysis, leveraging low-level programming and multi-threading techniques to maximise performance.</p>
<br>
<div class="open-on-github">
<a href="https://github.com/leandrotiburske/bionet-rs" target="_blank" >
<p>Open on GitHub</p>
</a>
<a href="https://github.com/leandrotiburske/bionet-rs" target="_blank">
<img src="./img/github.svg" height="25px">
</a>
</div>
</div>
<div class="repo">
<img src="./img/umap.jpeg">
<h3>Transcriptomics of Bipolar Disorder</h3>
<div class="technologies-portfolio">
<img src="./img/R_logo.svg.png" title="R">
<img src="./img/Bash_Logo_black_and_white_icon_only.svg.png" title="Bash">
</div>
<p>For my Bachelor's thesis, bulk and single-cell RNA sequencing analyses were conducted on brain samples obtained from both control and bipolar individuals. The project encompassed the entire process, from the initial processing of raw data through to the examination of differential expression, coexpression patterns, and cell-cell communication.</p>
<br>
<div class="open-on-github">
<a href="https://github.com/leandrotiburske/BipolarDisorder/" target="_blank" >
<p>Open on GitHub</p>
</a>
<a href="https://github.com/leandrotiburske/BipolarDisorder/" target="_blank">
<img src="./img/github.svg" height="25px">
</a>
</div>
</div>
<div class="repo">
<img src="./img/linkoping-uneversity-.png">
<h3>Metagenomics and Gut-Brain Axis</h3>
<div class="technologies-portfolio">
<img src="./img/Bash_Logo_black_and_white_icon_only.svg.png" title="Bash">
</div>
<p>Developed during my research internship at Linköping University in Sweden, the aim of this project was to perform metagenomic sequencing on mouse samples to understand the impact of a high-fat diet on cognition, behaviour, and microbiota. The analysis was conducted on a high-performance computing system (HPC) managed with Slurm.</p>
<br>
<div class="open-on-github">
<a href="https://github.com/leandrotiburske/metagenomics_HFD/" target="_blank" >
<p>Open on GitHub</p>
</a>
<a href="https://github.com/leandrotiburske/metagenomics_HFD/" target="_blank">
<img src="./img/github.svg" height="25px">
</a>
</div>
</div>
<div class="repo">
<img src="./img/coding.svg">
<h3>This website</h3>
<div class="technologies-portfolio">
<img src="./img/HTML5_Badge.svg.png" title="HTML">
<img src="./img/CSS3_logo.svg" title="CSS">
</div>
<p>Built with HTML and CSS and hosted on GitHub Pages, this site allows me to practice my front-end skills while sharing my professional background.</p>
<br>
<div class="open-on-github">
<a href="https://github.com/leandrotiburske/tiburske-website" target="_blank" >
<p>Open on GitHub</p>
</a>
<a href="https://github.com/leandrotiburske/tiburske-website" target="_blank">
<img src="./img/github.svg" height="25px">
</a>
</div>
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<h2 id="contact-title">Contact me</h2>
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<img src="./img/email.png"> <a>tiburskeleandro@gmail.com</a>
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<img src="./img/linkedin_blue.png"> <a href="https://www.linkedin.com/in/leandro-tiburske-a323b61b2/" target="_blank">LinkedIn</a>
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<img src="./img/github.svg""> <a href="https://github.com/leandrotiburske" target="_blank">GitHub</a>
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<span class="mb-3 mb-md-0 mr-0 text-body-secondary">© 2024 Leandro Tiburske</span>
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