WTS / WES both works?

[linuxbioinfoguy]

just want to make sure, I assume using WTS data is the best for this package, but correct me if I am wrong, or it can both works and filter out those non-recombinant reads in the corresponding region from cells that are not immunocell-origin ( only ) ? Thanks!

[mourisl]

I have tested TRUST4 on WXS sequencing data before, and it worked and reported a decent number of CDR3s. But I haven't thoroughly evaluated those results yet.

Those could be from the reads that partially matched V, J, C genes so the exon primers can still capture them.