diff --git a/.github/workflows/seccomp.yml b/.github/workflows/seccomp.yml
new file mode 100644
index 00000000000..053bce0dd8c
--- /dev/null
+++ b/.github/workflows/seccomp.yml
@@ -0,0 +1,67 @@
+name: seccomp
+on:
+  pull_request:
+    branches: [main]
+  merge_group:
+    types: [checks_requested]
+    branches: [main]
+
+jobs:
+  ubuntu:
+    runs-on: ubuntu-latest
+    steps:
+      - name: install dependencies
+        run: |
+          sudo apt update
+          sudo apt install cmake
+          # For default libcrypto
+          sudo apt install libssl-dev
+          # For seccomp
+          sudo apt install libseccomp-dev
+          # For aws-lc
+          sudo apt install clang golang
+          
+      - name: checkout s2n-tls
+        uses: actions/checkout@v4
+        
+      - name: checkout aws-lc
+        uses: actions/checkout@v4
+        with:
+          repository: aws/aws-lc
+          path: awslc
+
+      - name: build awslc
+        # See https://github.com/aws/aws-lc/blob/main/BUILDING.md#building
+        working-directory: awslc
+        run: |
+          cmake -B build
+          make -C build
+          cmake --install build --prefix install
+
+      - name: seccomp with default libcrypto
+        # TODO: There are still issues with openssl running with seccomp.
+        # Disable for now.
+        if: false
+        run: |
+          cmake -Bbuild \
+            -DSECCOMP=1 \
+            -DCMAKE_BUILD_TYPE=Release \
+            -DCMAKE_INSTALL_PREFIX=install
+          cmake --build build -j $(nproc)
+          CTEST_PARALLEL_LEVEL=$(nproc) ctest --test-dir build
+          cmake --install build
+          ./build/bin/s2nc localhost 8000 | grep "libcrypto" | grep -v "AWS-LC"
+          rm -rf build
+
+      - name: seccomp with aws-lc
+        run: |
+          cmake -Bbuild \
+            -DSECCOMP=1 \
+            -DCMAKE_BUILD_TYPE=Release \
+            -DCMAKE_PREFIX_PATH=awslc/install \
+            -DCMAKE_INSTALL_PREFIX=install
+          cmake --build build -j $(nproc)
+          CTEST_PARALLEL_LEVEL=$(nproc) ctest --test-dir build
+          cmake --install build
+          ./build/bin/s2nc localhost 8000 | grep "libcrypto" | grep "AWS-LC"
+          rm -rf build
diff --git a/CMakeLists.txt b/CMakeLists.txt
index c89bae8a817..fa01a3c7ee9 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -39,6 +39,7 @@ option(S2N_INSTALL_S2NC_S2ND "Install the binaries s2nc and s2nd" OFF)
 option(S2N_USE_CRYPTO_SHARED_LIBS "For S2N to use shared libs in Findcrypto" OFF)
 option(TSAN "Enable ThreadSanitizer to test thread safety" OFF)
 option(ASAN "Enable AddressSanitizer to test memory safety" OFF)
+option(SECCOMP "Link with seccomp and run seccomp tests" OFF)
 
 # Turn BUILD_TESTING=ON by default
 include(CTest)
@@ -452,6 +453,11 @@ if (BUILD_TESTING)
     target_include_directories(testss2n PUBLIC tests)
     target_compile_options(testss2n PRIVATE -std=gnu99)
     target_link_libraries(testss2n PUBLIC ${PROJECT_NAME})
+    if (SECCOMP)
+        message(STATUS "Linking tests with seccomp")
+        target_link_libraries(testss2n PRIVATE seccomp)
+        target_compile_definitions(testss2n PRIVATE SECCOMP)
+    endif()
 
     if (S2N_INTERN_LIBCRYPTO)
         # if libcrypto was interned, rewrite libcrypto symbols so use of internal functions will link correctly
diff --git a/tests/s2n_test.h b/tests/s2n_test.h
index 696ba68ed0d..3ad2c168783 100644
--- a/tests/s2n_test.h
+++ b/tests/s2n_test.h
@@ -30,6 +30,8 @@
 
 int test_count;
 
+bool s2n_use_color_in_output = true;
+
 /* Macro definitions for calls that occur within BEGIN_TEST() and END_TEST() to preserve the SKIPPED test behavior
  * by ignoring the test_count, keeping it as 0 to indicate that a test was skipped. */
 #define EXPECT_TRUE_WITHOUT_COUNT( condition )    do { if ( !(condition) ) { FAIL_MSG( #condition " is not true "); } } while(0)
@@ -40,7 +42,7 @@ int test_count;
 #define EXPECT_SUCCESS_WITHOUT_COUNT( function_call )  EXPECT_NOT_EQUAL_WITHOUT_COUNT( (function_call) ,  -1 )
 
 #define END_TEST_PRINT()                                                            \
-    if (isatty(fileno(stdout))) {                                                   \
+    if (s2n_use_color_in_output && isatty(fileno(stdout))) {                                                   \
         if (test_count) {                                                           \
             fprintf(stdout, "\033[32;1mPASSED\033[0m %10d tests\n", test_count );   \
         }                                                                           \
@@ -105,7 +107,7 @@ int test_count;
                           /* isatty and s2n_print_stacktrace will overwrite errno on failure */ \
                           int real_errno = errno; \
                           s2n_print_stacktrace(stderr); \
-                          if (isatty(fileno(stderr))) { \
+                          if (s2n_use_color_in_output && isatty(fileno(stderr))) { \
                             errno = real_errno; \
                             fprintf(stderr, "\033[31;1mFAILED test %d\033[0m\n%s (%s:%d)\nError Message: '%s'\n Debug String: '%s'\n System Error: %s (%d)\n", test_count, (msg), __FILE__, __LINE__, s2n_strerror(s2n_errno, "EN"), s2n_strerror_debug(s2n_errno, "EN"), strerror(errno), errno); \
                           } \
diff --git a/tests/testlib/s2n_seccomp.c b/tests/testlib/s2n_seccomp.c
new file mode 100644
index 00000000000..db956e8f288
--- /dev/null
+++ b/tests/testlib/s2n_seccomp.c
@@ -0,0 +1,76 @@
+/*
+ * Copyright Amazon.com, Inc. or its affiliates. All Rights Reserved.
+ *
+ * Licensed under the Apache License, Version 2.0 (the "License").
+ * You may not use this file except in compliance with the License.
+ * A copy of the License is located at
+ *
+ *  http://aws.amazon.com/apache2.0
+ *
+ * or in the "license" file accompanying this file. This file is distributed
+ * on an "AS IS" BASIS, WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either
+ * express or implied. See the License for the specific language governing
+ * permissions and limitations under the License.
+ */
+
+#include "testlib/s2n_testlib.h"
+#include "utils/s2n_safety.h"
+
+#ifdef SECCOMP
+
+    #include <seccomp.h>
+
+DEFINE_POINTER_CLEANUP_FUNC(scmp_filter_ctx, seccomp_release);
+
+extern bool s2n_use_color_in_output;
+
+bool s2n_is_seccomp_supported()
+{
+    return true;
+}
+
+S2N_RESULT s2n_seccomp_init()
+{
+    /* Using SCMP_ACT_TRAP instead of SCMP_ACT_KILL makes this test easier
+     * to debug. GDB will report exactly which syscalls triggered the signal.
+     */
+    DEFER_CLEANUP(scmp_filter_ctx ctx = seccomp_init(SCMP_ACT_TRAP),
+            seccomp_release_pointer);
+    RESULT_ENSURE_REF(ctx);
+
+    /* Basic requirements */
+    RESULT_GUARD_POSIX(seccomp_rule_add(ctx, SCMP_ACT_ALLOW, SCMP_SYS(access), 0));
+    RESULT_GUARD_POSIX(seccomp_rule_add(ctx, SCMP_ACT_ALLOW, SCMP_SYS(brk), 0));
+    RESULT_GUARD_POSIX(seccomp_rule_add(ctx, SCMP_ACT_ALLOW, SCMP_SYS(close), 0));
+    RESULT_GUARD_POSIX(seccomp_rule_add(ctx, SCMP_ACT_ALLOW, SCMP_SYS(exit_group), 0));
+    RESULT_GUARD_POSIX(seccomp_rule_add(ctx, SCMP_ACT_ALLOW, SCMP_SYS(fstat), 0));
+    RESULT_GUARD_POSIX(seccomp_rule_add(ctx, SCMP_ACT_ALLOW, SCMP_SYS(futex), 0));
+    RESULT_GUARD_POSIX(seccomp_rule_add(ctx, SCMP_ACT_ALLOW, SCMP_SYS(getrandom), 0));
+    RESULT_GUARD_POSIX(seccomp_rule_add(ctx, SCMP_ACT_ALLOW, SCMP_SYS(read), 0));
+    RESULT_GUARD_POSIX(seccomp_rule_add(ctx, SCMP_ACT_ALLOW, SCMP_SYS(write), 0));
+
+    /* Requirements for Ubuntu22 */
+    RESULT_GUARD_POSIX(seccomp_rule_add(ctx, SCMP_ACT_ALLOW, SCMP_SYS(clock_gettime), 0));
+    RESULT_GUARD_POSIX(seccomp_rule_add(ctx, SCMP_ACT_ALLOW, SCMP_SYS(newfstatat), 0));
+
+    /* See https://github.com/aws/aws-lc/blob/main/SANDBOXING.md#fork-protection */
+    RESULT_GUARD_POSIX(seccomp_rule_add(ctx, SCMP_ACT_ERRNO(EINVAL), SCMP_SYS(madvise), 0));
+
+    RESULT_GUARD_POSIX(seccomp_load(ctx));
+    s2n_use_color_in_output = false;
+    return S2N_RESULT_OK;
+}
+
+#else
+
+bool s2n_is_seccomp_supported()
+{
+    return false;
+}
+
+S2N_RESULT s2n_seccomp_init()
+{
+    return S2N_RESULT_OK;
+}
+
+#endif
diff --git a/tests/testlib/s2n_testlib.h b/tests/testlib/s2n_testlib.h
index 60effca24de..ec9a3a36b7f 100644
--- a/tests/testlib/s2n_testlib.h
+++ b/tests/testlib/s2n_testlib.h
@@ -298,3 +298,6 @@ S2N_RESULT s2n_resumption_test_ticket_key_setup(struct s2n_config *config);
 #define S2N_CHECKED_BLOB_FROM_HEX(name, check, hex)        \
     DEFER_CLEANUP(struct s2n_blob name = { 0 }, s2n_free); \
     check(s2n_blob_alloc_from_hex_with_whitespace(&name, (const char *) hex));
+
+bool s2n_is_seccomp_supported();
+S2N_RESULT s2n_seccomp_init();
diff --git a/tests/unit/s2n_seccomp_failure_test.c b/tests/unit/s2n_seccomp_failure_test.c
new file mode 100644
index 00000000000..a33583e2a07
--- /dev/null
+++ b/tests/unit/s2n_seccomp_failure_test.c
@@ -0,0 +1,62 @@
+/*
+ * Copyright Amazon.com, Inc. or its affiliates. All Rights Reserved.
+ *
+ * Licensed under the Apache License, Version 2.0 (the "License").
+ * You may not use this file except in compliance with the License.
+ * A copy of the License is located at
+ *
+ *  http://aws.amazon.com/apache2.0
+ *
+ * or in the "license" file accompanying this file. This file is distributed
+ * on an "AS IS" BASIS, WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either
+ * express or implied. See the License for the specific language governing
+ * permissions and limitations under the License.
+ */
+
+#include <signal.h>
+#include <stdio.h>
+#include <sys/stat.h>
+
+#include "s2n_test.h"
+#include "testlib/s2n_testlib.h"
+
+bool s2n_fstat_success = false;
+bool s2n_open_success = false;
+
+void s2n_detect_open_violation(int sig)
+{
+    EXPECT_EQUAL(sig, SIGSYS);
+
+    EXPECT_TRUE(s2n_fstat_success);
+    EXPECT_FALSE(s2n_open_success);
+
+    END_TEST_PRINT();
+    exit(0);
+}
+
+int main(int argc, char **argv)
+{
+    BEGIN_TEST();
+
+    if (!s2n_is_seccomp_supported()) {
+        END_TEST();
+    }
+
+    const struct sigaction action = {
+        .sa_handler = s2n_detect_open_violation,
+    };
+    EXPECT_EQUAL(sigaction(SIGSYS, &action, NULL), 0);
+
+    EXPECT_OK(s2n_seccomp_init());
+
+    /* The seccomp filter allows fstat */
+    struct stat st = { 0 };
+    EXPECT_SUCCESS(fstat(0, &st));
+    s2n_fstat_success = true;
+
+    /* The seccomp filter does NOT allow open */
+    fopen(S2N_DEFAULT_TEST_CERT_CHAIN, "r");
+    s2n_open_success = true;
+
+    FAIL_MSG("test unexpectedly succeeded");
+}
diff --git a/tests/unit/s2n_seccomp_handshake_test.c b/tests/unit/s2n_seccomp_handshake_test.c
new file mode 100644
index 00000000000..c0487577831
--- /dev/null
+++ b/tests/unit/s2n_seccomp_handshake_test.c
@@ -0,0 +1,75 @@
+/*
+ * Copyright Amazon.com, Inc. or its affiliates. All Rights Reserved.
+ *
+ * Licensed under the Apache License, Version 2.0 (the "License").
+ * You may not use this file except in compliance with the License.
+ * A copy of the License is located at
+ *
+ *  http://aws.amazon.com/apache2.0
+ *
+ * or in the "license" file accompanying this file. This file is distributed
+ * on an "AS IS" BASIS, WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either
+ * express or implied. See the License for the specific language governing
+ * permissions and limitations under the License.
+ */
+
+#include "api/s2n.h"
+#include "s2n_test.h"
+#include "testlib/s2n_testlib.h"
+
+int main(int argc, char **argv)
+{
+    BEGIN_TEST();
+
+    /* We don't use s2n_test_cert_chain_and_key_new because we want to explicitly
+     * only do the PEM file read before enabling seccomp.
+     */
+    char cert_chain_pem[S2N_MAX_TEST_PEM_SIZE] = { 0 };
+    char private_key_pem[S2N_MAX_TEST_PEM_SIZE] = { 0 };
+    EXPECT_SUCCESS(s2n_read_test_pem(S2N_DEFAULT_ECDSA_TEST_CERT_CHAIN,
+            cert_chain_pem, S2N_MAX_TEST_PEM_SIZE));
+    EXPECT_SUCCESS(s2n_read_test_pem(S2N_DEFAULT_ECDSA_TEST_PRIVATE_KEY,
+            private_key_pem, S2N_MAX_TEST_PEM_SIZE));
+
+    /* No unexpected syscalls allowed beyond this point */
+    EXPECT_OK(s2n_seccomp_init());
+
+    DEFER_CLEANUP(struct s2n_cert_chain_and_key *chain_and_key = s2n_cert_chain_and_key_new(),
+            s2n_cert_chain_and_key_ptr_free);
+    EXPECT_SUCCESS(s2n_cert_chain_and_key_load_pem(chain_and_key, cert_chain_pem, private_key_pem));
+
+    DEFER_CLEANUP(struct s2n_config *config = s2n_config_new_minimal(), s2n_config_ptr_free);
+    EXPECT_SUCCESS(s2n_config_add_cert_chain_and_key_to_store(config, chain_and_key));
+    EXPECT_SUCCESS(s2n_config_add_pem_to_trust_store(config, cert_chain_pem));
+
+    const char *security_policies[] = { "default", "default_tls13" };
+
+    for (size_t i = 0; i < s2n_array_len(security_policies); i++) {
+        DEFER_CLEANUP(struct s2n_connection *client = s2n_connection_new(S2N_CLIENT),
+                s2n_connection_ptr_free);
+        EXPECT_NOT_NULL(client);
+        EXPECT_SUCCESS(s2n_connection_set_config(client, config));
+        EXPECT_SUCCESS(s2n_connection_set_cipher_preferences(client, security_policies[i]));
+        EXPECT_SUCCESS(s2n_set_server_name(client, "127.0.0.1"));
+
+        DEFER_CLEANUP(struct s2n_connection *server = s2n_connection_new(S2N_SERVER),
+                s2n_connection_ptr_free);
+        EXPECT_NOT_NULL(server);
+        EXPECT_SUCCESS(s2n_connection_set_config(server, config));
+        EXPECT_SUCCESS(s2n_connection_set_cipher_preferences(server, security_policies[i]));
+
+        DEFER_CLEANUP(struct s2n_test_io_stuffer_pair io_pair = { 0 }, s2n_io_stuffer_pair_free);
+        EXPECT_OK(s2n_io_stuffer_pair_init(&io_pair));
+        EXPECT_OK(s2n_connections_set_io_stuffer_pair(client, server, &io_pair));
+        EXPECT_SUCCESS(s2n_negotiate_test_server_and_client(server, client));
+
+        const uint8_t data[] = "hello world";
+        uint8_t buffer[100] = { 0 };
+        s2n_blocked_status blocked = S2N_NOT_BLOCKED;
+        EXPECT_EQUAL(s2n_send(client, data, sizeof(data), &blocked), sizeof(data));
+        EXPECT_EQUAL(s2n_recv(server, buffer, sizeof(buffer), &blocked), sizeof(data));
+        EXPECT_BYTEARRAY_EQUAL(buffer, data, sizeof(data));
+    }
+
+    END_TEST();
+}
diff --git a/utils/s2n_init.c b/utils/s2n_init.c
index 3c561106ea8..9e9f91314b3 100644
--- a/utils/s2n_init.c
+++ b/utils/s2n_init.c
@@ -87,6 +87,10 @@ int s2n_init(void)
         s2n_stack_traces_enabled_set(true);
     }
 
+#if defined(OPENSSL_IS_BORINGSSL) || defined(OPENSSL_IS_AWSLC)
+    CRYPTO_pre_sandbox_init();
+#endif
+
     initialized = true;
 
     return S2N_SUCCESS;