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DESCRIPTION
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DESCRIPTION
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Type: Package
Package: EpiCompare
Title: Comparison, Benchmarking & QC of Epigenomic Datasets
Version: 1.9.10
Authors@R: c(
person(given = "Sera", family = "Choi",
email = "serachoi1230@gmail.com",
role = "aut",
comment = c(ORCID = "0000-0002-5077-1984")),
person(given="Brian", family="Schilder",
email = "brian_schilder@alumni.brown.edu",
role = "aut",
comment = c(ORCID = "0000-0001-5949-2191")),
person(given="Leyla", family="Abbasova",
email = "profernitsky@gmail.com",
role = "aut"),
person(given="Alan", family="Murphy",
email = "alanmurph94@hotmail.com",
role = "aut",
comment = c(ORCID = "0000-0002-2487-8753")),
person(given="Nathan", family="Skene",
email = "nathan.skene@gmail.com",
role = "aut",
comment = c(ORCID = "0000-0002-6807-3180")),
person(given="Thomas", family="Roberts",
email = "tomroberts.work15@gmail.com",
role = "ctb"),
person(given="Hiranyamaya", family="Dash",
email = "hdash.work@gmail.com",
role = "cre",
comment = c(ORCID = "0009-0005-5514-505X"))
)
Description: EpiCompare is used to compare and analyse epigenetic datasets
for quality control and benchmarking purposes.
The package outputs an HTML report consisting of three sections:
(1. General metrics) Metrics on peaks (percentage of blacklisted and
non-standard peaks, and peak widths) and fragments (duplication rate)
of samples,
(2. Peak overlap) Percentage and statistical significance of
overlapping and non-overlapping peaks. Also includes upset plot and
(3. Functional annotation) functional annotation
(ChromHMM, ChIPseeker and enrichment analysis) of peaks.
Also includes peak enrichment around TSS.
License: GPL-3
URL: https://github.com/neurogenomics/EpiCompare
BugReports: https://github.com/neurogenomics/EpiCompare/issues
Depends:
R (>= 4.2.0)
Imports:
AnnotationHub,
ChIPseeker,
data.table,
genomation,
GenomicRanges,
IRanges,
GenomeInfoDb,
ggplot2 (>= 3.5.0),
htmltools,
methods,
plotly,
reshape2,
rmarkdown,
rtracklayer,
stats,
stringr,
utils,
BiocGenerics,
downloadthis,
parallel
Suggests:
rworkflows,
BiocFileCache,
BiocParallel,
BiocStyle,
clusterProfiler,
GenomicAlignments,
grDevices,
knitr,
org.Hs.eg.db,
testthat (>= 3.0.0),
tidyr,
TxDb.Hsapiens.UCSC.hg19.knownGene,
TxDb.Hsapiens.UCSC.hg38.knownGene,
TxDb.Mmusculus.UCSC.mm9.knownGene,
TxDb.Mmusculus.UCSC.mm10.knownGene,
BSgenome.Hsapiens.UCSC.hg19,
BSgenome.Hsapiens.UCSC.hg38,
BSgenome.Mmusculus.UCSC.mm9,
BSgenome.Mmusculus.UCSC.mm10,
ComplexUpset,
plyranges,
scales,
Matrix,
consensusSeekeR,
heatmaply,
viridis
VignetteBuilder:
knitr
biocViews: Epigenetics, Genetics, QualityControl, ChIPSeq,
MultipleComparison, FunctionalGenomics, ATACSeq, DNaseSeq
Config/testthat/edition: 3
Encoding: UTF-8
LazyData: FALSE
RoxygenNote: 7.3.2