diff --git a/.github/workflows/phpunit-mysql-sharding.yml b/.github/workflows/phpunit-mysql-sharding.yml
new file mode 100644
index 0000000000000..6d089defe4f2a
--- /dev/null
+++ b/.github/workflows/phpunit-mysql-sharding.yml
@@ -0,0 +1,184 @@
+# This workflow is provided via the organization template repository
+#
+# https://github.com/nextcloud/.github
+# https://docs.github.com/en/actions/learn-github-actions/sharing-workflows-with-your-organization
+#
+# SPDX-FileCopyrightText: 2022-2024 Nextcloud GmbH and Nextcloud contributors
+# SPDX-License-Identifier: MIT
+
+name: PHPUnit sharding
+
+on:
+  pull_request:
+  schedule:
+    - cron: "5 2 * * *"
+
+permissions:
+  contents: read
+
+concurrency:
+  group: phpunit-mysql-sharding-${{ github.head_ref || github.run_id }}
+  cancel-in-progress: true
+
+jobs:
+  changes:
+    runs-on: ubuntu-latest-low
+
+    outputs:
+      src: ${{ steps.changes.outputs.src }}
+
+    steps:
+      - uses: dorny/paths-filter@de90cc6fb38fc0963ad72b210f1f284cd68cea36 # v3.0.2
+        id: changes
+        continue-on-error: true
+        with:
+          filters: |
+            src:
+              - '.github/workflows/**'
+              - '3rdparty/**'
+              - '**/appinfo/**'
+              - '**/lib/**'
+              - '**/templates/**'
+              - '**/tests/**'
+              - 'vendor/**'
+              - 'vendor-bin/**'
+              - '.php-cs-fixer.dist.php'
+              - 'composer.json'
+              - 'composer.lock'
+              - '**.php'
+
+  phpunit-mysql:
+    runs-on: ubuntu-latest
+
+    needs: changes
+    if: needs.changes.outputs.src != 'false'
+
+    strategy:
+      matrix:
+        php-versions: ['8.1']
+        mysql-versions: ['8.4']
+
+    name: Sharding - MySQL ${{ matrix.mysql-versions }} (PHP ${{ matrix.php-versions }}) - database tests
+
+    services:
+      cache:
+        image: ghcr.io/nextcloud/continuous-integration-redis:latest
+        ports:
+          - 6379:6379/tcp
+        options: --health-cmd="redis-cli ping" --health-interval=10s --health-timeout=5s --health-retries=3
+
+      mysql:
+        image: ghcr.io/nextcloud/continuous-integration-mysql-${{ matrix.mysql-versions }}:latest
+        ports:
+          - 4444:3306/tcp
+        env:
+          MYSQL_ROOT_PASSWORD: rootpassword
+          MYSQL_USER: oc_autotest
+          MYSQL_PASSWORD: nextcloud
+          MYSQL_DATABASE: oc_autotest
+        options: --health-cmd="mysqladmin ping" --health-interval 5s --health-timeout 2s --health-retries 10
+      shard1:
+        image: ghcr.io/nextcloud/continuous-integration-mysql-${{ matrix.mysql-versions }}:latest
+        ports:
+          - 5001:3306/tcp
+        env:
+          MYSQL_ROOT_PASSWORD: rootpassword
+          MYSQL_USER: oc_autotest
+          MYSQL_PASSWORD: nextcloud
+          MYSQL_DATABASE: oc_autotest
+        options: --health-cmd="mysqladmin ping" --health-interval 5s --health-timeout 2s --health-retries 10
+      shard2:
+        image: ghcr.io/nextcloud/continuous-integration-mysql-${{ matrix.mysql-versions }}:latest
+        ports:
+          - 5002:3306/tcp
+        env:
+          MYSQL_ROOT_PASSWORD: rootpassword
+          MYSQL_USER: oc_autotest
+          MYSQL_PASSWORD: nextcloud
+          MYSQL_DATABASE: oc_autotest
+        options: --health-cmd="mysqladmin ping" --health-interval 5s --health-timeout 2s --health-retries 10
+      shard3:
+        image: ghcr.io/nextcloud/continuous-integration-mysql-${{ matrix.mysql-versions }}:latest
+        ports:
+          - 5003:3306/tcp
+        env:
+          MYSQL_ROOT_PASSWORD: rootpassword
+          MYSQL_USER: oc_autotest
+          MYSQL_PASSWORD: nextcloud
+          MYSQL_DATABASE: oc_autotest
+        options: --health-cmd="mysqladmin ping" --health-interval 5s --health-timeout 2s --health-retries 10
+      shard4:
+        image: ghcr.io/nextcloud/continuous-integration-mysql-${{ matrix.mysql-versions }}:latest
+        ports:
+          - 5004:3306/tcp
+        env:
+          MYSQL_ROOT_PASSWORD: rootpassword
+          MYSQL_USER: oc_autotest
+          MYSQL_PASSWORD: nextcloud
+          MYSQL_DATABASE: oc_autotest
+        options: --health-cmd="mysqladmin ping" --health-interval 5s --health-timeout 2s --health-retries 10
+
+    steps:
+      - name: Checkout server
+        uses: actions/checkout@692973e3d937129bcbf40652eb9f2f61becf3332
+        with:
+          submodules: true
+
+      - name: Set up php ${{ matrix.php-versions }}
+        uses: shivammathur/setup-php@2e947f1f6932d141d076ca441d0e1e881775e95b #v2.31.0
+        with:
+          php-version: ${{ matrix.php-versions }}
+          # https://docs.nextcloud.com/server/stable/admin_manual/installation/source_installation.html#prerequisites-for-manual-installation
+          extensions: bz2, ctype, curl, dom, fileinfo, gd, iconv, intl, json, libxml, mbstring, openssl, pcntl, posix, redis, session, simplexml, xmlreader, xmlwriter, zip, zlib, mysql, pdo_mysql
+          coverage: ${{ matrix.coverage && 'xdebug' || 'none' }}
+          ini-file: development
+        env:
+          GITHUB_TOKEN: ${{ secrets.GITHUB_TOKEN }}
+
+      - name: Set up dependencies
+        run: composer i
+
+      - name: Enable ONLY_FULL_GROUP_BY MySQL option
+        run: |
+          echo "SET GLOBAL sql_mode=(SELECT CONCAT(@@sql_mode,',ONLY_FULL_GROUP_BY'));" | mysql -h 127.0.0.1 -P 4444 -u root -prootpassword
+          echo "SELECT @@sql_mode;" | mysql -h 127.0.0.1 -P 4444 -u root -prootpassword
+
+      - name: Set up Nextcloud
+        env:
+          DB_PORT: 4444
+          SHARDING: 1
+        run: |
+          mkdir data
+          cp tests/redis.config.php config/
+          cp tests/preseed-config.php config/config.php
+          ./occ maintenance:install --verbose --database=mysql --database-name=nextcloud --database-host=127.0.0.1 --database-port=$DB_PORT --database-user=root --database-pass=rootpassword --admin-user admin --admin-pass admin
+          php -f tests/enable_all.php | grep -i -C9999 error && echo "Error during app setup" && exit 1 || exit 0
+
+      - name: PHPUnit
+        run: composer run test:db ${{ matrix.coverage && ' -- --coverage-clover ./clover.db.xml' || '' }}
+
+      - name: Upload db code coverage
+        if: ${{ !cancelled() && matrix.coverage }}
+        uses: codecov/codecov-action@v4.1.1
+        with:
+          files: ./clover.db.xml
+          flags: phpunit-mysql
+
+      - name: Print logs
+        if: always()
+        run: |
+          cat data/nextcloud.log
+
+  summary:
+    permissions:
+      contents: none
+    runs-on: ubuntu-latest-low
+    needs: [changes, phpunit-mysql]
+
+    if: always()
+
+    name: phpunit-mysql-summary
+
+    steps:
+      - name: Summary status
+        run: if ${{ needs.changes.outputs.src != 'false' && needs.phpunit-mysql.result != 'success' }}; then exit 1; fi
diff --git a/tests/preseed-config.php b/tests/preseed-config.php
index 3739335676abb..e83a71f923b2f 100644
--- a/tests/preseed-config.php
+++ b/tests/preseed-config.php
@@ -78,3 +78,24 @@
 		]
 	];
 }
+
+if (getenv('SHARDING') == '1') {
+	$CONFIG['dbsharding'] = [
+		"filecache" => [
+			"shards" => [
+				[
+					"port" => 5001,
+				],
+				[
+					"port" => 5002,
+				],
+				[
+					"port" => 5003,
+				],
+				[
+					"port" => 5004,
+				],
+			]
+ 	   ]
+	];
+}