diff --git a/.pre-commit-config.yaml b/.pre-commit-config.yaml
index 4406ca22..b2de03d4 100644
--- a/.pre-commit-config.yaml
+++ b/.pre-commit-config.yaml
@@ -29,6 +29,23 @@ repos:
           - types-Markdown
           - types-setuptools
 
+  - repo: local
+    hooks:
+      - id: ty
+        name: ty type checker
+        entry: uv run ty check
+        language: system
+        types: [python]
+        args:
+          [
+            --exclude,
+            "**/venv/**",
+            --exclude,
+            "**/.venv/**",
+            --exclude,
+            "**/__pycache__/**",
+          ]
+
   - repo: https://github.com/renovatebot/pre-commit-hooks
     rev: 38.142.7
     hooks:
diff --git a/pulumi/test_datasets/pyproject.toml b/pulumi/test_datasets/pyproject.toml
index b5a5b10d..adbccfc5 100644
--- a/pulumi/test_datasets/pyproject.toml
+++ b/pulumi/test_datasets/pyproject.toml
@@ -10,3 +10,24 @@ dependencies = [
     "pulumi-github>=6.7.2",
     "pulumi-onepassword>=1.1.3",
 ]
+
+[dependency-groups]
+dev = [
+    "ty>=0.0.0a6",
+    "mypy>=1.11.1",
+]
+
+# [tool.ty]
+# Configuration for ty type checker - using CLI args for now
+# ty is in pre-alpha, configuration format may change
+
+[tool.mypy]
+# Keep mypy configuration for comparison/fallback
+python_version = "3.12"
+check_untyped_defs = true
+disallow_any_generics = true
+disallow_incomplete_defs = true
+disallow_untyped_defs = true
+no_implicit_optional = true
+warn_redundant_casts = true
+warn_unused_ignores = true
diff --git a/pulumi/test_datasets/uv.lock b/pulumi/test_datasets/uv.lock
index e6703818..ba60f265 100644
--- a/pulumi/test_datasets/uv.lock
+++ b/pulumi/test_datasets/uv.lock
@@ -72,6 +72,41 @@ wheels = [
     { url = "https://files.pythonhosted.org/packages/a2/df/133216989fe7e17caeafd7ff5b17cc82c4e722025d0b8d5d2290c11fe2e6/grpcio-1.66.2-cp313-cp313-win_amd64.whl", hash = "sha256:fb70487c95786e345af5e854ffec8cb8cc781bcc5df7930c4fbb7feaa72e1cdf", size = 4278018, upload-time = "2024-09-28T12:39:13.196Z" },
 ]
 
+[[package]]
+name = "mypy"
+version = "1.16.1"
+source = { registry = "https://pypi.org/simple" }
+dependencies = [
+    { name = "mypy-extensions" },
+    { name = "pathspec" },
+    { name = "typing-extensions" },
+]
+sdist = { url = "https://files.pythonhosted.org/packages/81/69/92c7fa98112e4d9eb075a239caa4ef4649ad7d441545ccffbd5e34607cbb/mypy-1.16.1.tar.gz", hash = "sha256:6bd00a0a2094841c5e47e7374bb42b83d64c527a502e3334e1173a0c24437bab", size = 3324747, upload-time = "2025-06-16T16:51:35.145Z" }
+wheels = [
+    { url = "https://files.pythonhosted.org/packages/b4/d6/39482e5fcc724c15bf6280ff5806548c7185e0c090712a3736ed4d07e8b7/mypy-1.16.1-cp312-cp312-macosx_10_13_x86_64.whl", hash = "sha256:af4792433f09575d9eeca5c63d7d90ca4aeceda9d8355e136f80f8967639183d", size = 11066493, upload-time = "2025-06-16T16:47:01.683Z" },
+    { url = "https://files.pythonhosted.org/packages/e6/e5/26c347890efc6b757f4d5bb83f4a0cf5958b8cf49c938ac99b8b72b420a6/mypy-1.16.1-cp312-cp312-macosx_11_0_arm64.whl", hash = "sha256:66df38405fd8466ce3517eda1f6640611a0b8e70895e2a9462d1d4323c5eb4b9", size = 10081687, upload-time = "2025-06-16T16:48:19.367Z" },
+    { url = "https://files.pythonhosted.org/packages/44/c7/b5cb264c97b86914487d6a24bd8688c0172e37ec0f43e93b9691cae9468b/mypy-1.16.1-cp312-cp312-manylinux_2_17_aarch64.manylinux2014_aarch64.manylinux_2_28_aarch64.whl", hash = "sha256:44e7acddb3c48bd2713994d098729494117803616e116032af192871aed80b79", size = 11839723, upload-time = "2025-06-16T16:49:20.912Z" },
+    { url = "https://files.pythonhosted.org/packages/15/f8/491997a9b8a554204f834ed4816bda813aefda31cf873bb099deee3c9a99/mypy-1.16.1-cp312-cp312-manylinux_2_17_x86_64.manylinux2014_x86_64.manylinux_2_28_x86_64.whl", hash = "sha256:0ab5eca37b50188163fa7c1b73c685ac66c4e9bdee4a85c9adac0e91d8895e15", size = 12722980, upload-time = "2025-06-16T16:37:40.929Z" },
+    { url = "https://files.pythonhosted.org/packages/df/f0/2bd41e174b5fd93bc9de9a28e4fb673113633b8a7f3a607fa4a73595e468/mypy-1.16.1-cp312-cp312-musllinux_1_2_x86_64.whl", hash = "sha256:dedb6229b2c9086247e21a83c309754b9058b438704ad2f6807f0d8227f6ebdd", size = 12903328, upload-time = "2025-06-16T16:34:35.099Z" },
+    { url = "https://files.pythonhosted.org/packages/61/81/5572108a7bec2c46b8aff7e9b524f371fe6ab5efb534d38d6b37b5490da8/mypy-1.16.1-cp312-cp312-win_amd64.whl", hash = "sha256:1f0435cf920e287ff68af3d10a118a73f212deb2ce087619eb4e648116d1fe9b", size = 9562321, upload-time = "2025-06-16T16:48:58.823Z" },
+    { url = "https://files.pythonhosted.org/packages/28/e3/96964af4a75a949e67df4b95318fe2b7427ac8189bbc3ef28f92a1c5bc56/mypy-1.16.1-cp313-cp313-macosx_10_13_x86_64.whl", hash = "sha256:ddc91eb318c8751c69ddb200a5937f1232ee8efb4e64e9f4bc475a33719de438", size = 11063480, upload-time = "2025-06-16T16:47:56.205Z" },
+    { url = "https://files.pythonhosted.org/packages/f5/4d/cd1a42b8e5be278fab7010fb289d9307a63e07153f0ae1510a3d7b703193/mypy-1.16.1-cp313-cp313-macosx_11_0_arm64.whl", hash = "sha256:87ff2c13d58bdc4bbe7dc0dedfe622c0f04e2cb2a492269f3b418df2de05c536", size = 10090538, upload-time = "2025-06-16T16:46:43.92Z" },
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+    { url = "https://files.pythonhosted.org/packages/5a/fd/d486a0827a1c597b3b48b1bdef47228a6e9ee8102ab8c28f944cb83b65dc/mypy-1.16.1-cp313-cp313-win_amd64.whl", hash = "sha256:4f58ac32771341e38a853c5d0ec0dfe27e18e27da9cdb8bbc882d2249c71a3ee", size = 9573886, upload-time = "2025-06-16T16:36:43.589Z" },
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+]
+
+[[package]]
+name = "mypy-extensions"
+version = "1.1.0"
+source = { registry = "https://pypi.org/simple" }
+sdist = { url = "https://files.pythonhosted.org/packages/a2/6e/371856a3fb9d31ca8dac321cda606860fa4548858c0cc45d9d1d4ca2628b/mypy_extensions-1.1.0.tar.gz", hash = "sha256:52e68efc3284861e772bbcd66823fde5ae21fd2fdb51c62a211403730b916558", size = 6343, upload-time = "2025-04-22T14:54:24.164Z" }
+wheels = [
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+]
+
 [[package]]
 name = "parver"
 version = "0.5"
@@ -85,6 +120,15 @@ wheels = [
     { url = "https://files.pythonhosted.org/packages/0f/4c/f98024021bef4d44dce3613feebd702c7ad8883f777ff8488384c59e9774/parver-0.5-py3-none-any.whl", hash = "sha256:2281b187276c8e8e3c15634f62287b2fb6fe0efe3010f739a6bd1e45fa2bf2b2", size = 15172, upload-time = "2023-10-03T21:06:52.796Z" },
 ]
 
+[[package]]
+name = "pathspec"
+version = "0.12.1"
+source = { registry = "https://pypi.org/simple" }
+sdist = { url = "https://files.pythonhosted.org/packages/ca/bc/f35b8446f4531a7cb215605d100cd88b7ac6f44ab3fc94870c120ab3adbf/pathspec-0.12.1.tar.gz", hash = "sha256:a482d51503a1ab33b1c67a6c3813a26953dbdc71c31dacaef9a838c4e29f5712", size = 51043, upload-time = "2023-12-10T22:30:45Z" }
+wheels = [
+    { url = "https://files.pythonhosted.org/packages/cc/20/ff623b09d963f88bfde16306a54e12ee5ea43e9b597108672ff3a408aad6/pathspec-0.12.1-py3-none-any.whl", hash = "sha256:a0d503e138a4c123b27490a4f7beda6a01c6f288df0e4a8b79c7eb0dc7b4cc08", size = 31191, upload-time = "2023-12-10T22:30:43.14Z" },
+]
+
 [[package]]
 name = "pip"
 version = "25.1.1"
@@ -210,6 +254,12 @@ dependencies = [
     { name = "pulumi-onepassword" },
 ]
 
+[package.dev-dependencies]
+dev = [
+    { name = "mypy" },
+    { name = "ty" },
+]
+
 [package.metadata]
 requires-dist = [
     { name = "pulumi", specifier = ">=3.173.0" },
@@ -217,3 +267,43 @@ requires-dist = [
     { name = "pulumi-github", specifier = ">=6.7.2" },
     { name = "pulumi-onepassword", specifier = ">=1.1.3" },
 ]
+
+[package.metadata.requires-dev]
+dev = [
+    { name = "mypy", specifier = ">=1.11.1" },
+    { name = "ty", specifier = ">=0.0.0a6" },
+]
+
+[[package]]
+name = "ty"
+version = "0.0.1a12"
+source = { registry = "https://pypi.org/simple" }
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diff --git a/pyproject.toml b/pyproject.toml
new file mode 100644
index 00000000..8f76721c
--- /dev/null
+++ b/pyproject.toml
@@ -0,0 +1,42 @@
+[project]
+name = "nf-core-ops"
+version = "0.1.0"
+description = "nf-core operations and infrastructure management"
+readme = "README.md"
+requires-python = ">=3.12"
+
+[dependency-groups]
+dev = [
+    "ty>=0.0.0a6",
+    "mypy>=1.11.1",
+    "pre-commit>=3.0.0",
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+]
+
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+# ty is in pre-alpha, configuration format may change
+
+[tool.mypy]
+# Keep mypy configuration for comparison/fallback
+python_version = "3.12"
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+disallow_incomplete_defs = true
+disallow_untyped_defs = true
+no_implicit_optional = true
+warn_redundant_casts = true
+warn_unused_ignores = true
+exclude = [
+    "venv/",
+    ".venv/",
+    "__pycache__/",
+]
+
+[tool.ruff]
+# Keep existing ruff configuration
+target-version = "py312"
+line-length = 88
+
+[tool.ruff.lint]
+extend-select = ["I"]  # isort 
\ No newline at end of file
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