diff --git a/change/@ni-nimble-components-54ec9080-33bb-47a6-a37d-d926c42de859.json b/change/@ni-nimble-components-54ec9080-33bb-47a6-a37d-d926c42de859.json
new file mode 100644
index 0000000000..897eb39604
--- /dev/null
+++ b/change/@ni-nimble-components-54ec9080-33bb-47a6-a37d-d926c42de859.json
@@ -0,0 +1,7 @@
+{
+  "type": "patch",
+  "comment": "Remove ListOptionOwner from Combobox to address issue found in Angular",
+  "packageName": "@ni/nimble-components",
+  "email": "26874831+atmgrifter00@users.noreply.github.com",
+  "dependentChangeType": "patch"
+}
diff --git a/packages/nimble-components/src/combobox/index.ts b/packages/nimble-components/src/combobox/index.ts
index 4f607c5439..e3da226ded 100644
--- a/packages/nimble-components/src/combobox/index.ts
+++ b/packages/nimble-components/src/combobox/index.ts
@@ -17,14 +17,10 @@ import { iconExclamationMarkTag } from '../icons/exclamation-mark';
 
 import { styles } from './styles';
 import type { ErrorPattern } from '../patterns/error/types';
-import type {
-    DropdownPattern,
-    ListOptionOwner
-} from '../patterns/dropdown/types';
+import type { DropdownPattern } from '../patterns/dropdown/types';
 import { DropdownAppearance } from '../patterns/dropdown/types';
 import type { AnchoredRegion } from '../anchored-region';
 import { template } from './template';
-import type { ListOption } from '../list-option';
 
 declare global {
     interface HTMLElementTagNameMap {
@@ -37,7 +33,7 @@ declare global {
  */
 export class Combobox
     extends FoundationCombobox
-    implements DropdownPattern, ErrorPattern, ListOptionOwner {
+    implements DropdownPattern, ErrorPattern {
     @attr
     public appearance: DropdownAppearance = DropdownAppearance.underline;
 
@@ -211,23 +207,6 @@ export class Combobox
         return returnValue;
     }
 
-    /**
-     * @internal
-     */
-    public registerOption(option: ListOption): void {
-        if (this.options.includes(option)) {
-            return;
-        }
-
-        // Adding an option to the end, ultimately, isn't the correct
-        // thing to do, as this will mean the option's index in the options,
-        // at least temporarily, does not match the DOM order. However, it
-        // is expected that a successive run of `slottedOptionsChanged` will
-        // correct this order issue. See 'https://github.com/ni/nimble/issues/1915'
-        // for more info.
-        this.options.push(option);
-    }
-
     protected override focusAndScrollOptionIntoView(): void {
         if (this.open) {
             super.focusAndScrollOptionIntoView();
diff --git a/packages/nimble-components/src/combobox/tests/combobox.spec.ts b/packages/nimble-components/src/combobox/tests/combobox.spec.ts
index 7b282bd515..15973059fc 100644
--- a/packages/nimble-components/src/combobox/tests/combobox.spec.ts
+++ b/packages/nimble-components/src/combobox/tests/combobox.spec.ts
@@ -9,7 +9,7 @@ import {
     waitAnimationFrame
 } from '../../utilities/tests/component';
 import { checkFullyInViewport } from '../../utilities/tests/intersection-observer';
-import { ListOption, listOptionTag } from '../../list-option';
+import { listOptionTag } from '../../list-option';
 
 async function setup(
     position?: string,
@@ -127,33 +127,6 @@ describe('Combobox', () => {
         await disconnect();
     });
 
-    it('option added directly to DOM synchronously registers with Combobox', async () => {
-        const { element, connect, disconnect } = await setup();
-        await connect();
-        element.selectedIndex = 0;
-        await waitForUpdatesAsync();
-        const newOption = new ListOption('foo', 'foo');
-        const registerOptionSpy = spyOn(
-            element,
-            'registerOption'
-        ).and.callThrough();
-        registerOptionSpy.calls.reset();
-        element.insertBefore(newOption, element.options[0]!);
-
-        expect(registerOptionSpy.calls.count()).toBe(1);
-        expect(element.options).toContain(newOption);
-
-        // While the option is registered synchronously as shown above,
-        // properties like selectedIndex will only be correct asynchronously
-        // See https://github.com/ni/nimble/issues/1915
-        expect(element.selectedIndex).toBe(0);
-        await waitForUpdatesAsync();
-        // This assertion shows that after 'slottedOptionsChanged' runs, the
-        // 'selectedIndex' state has been corrected to expected DOM order.
-        expect(element.selectedIndex).toBe(1);
-        await disconnect();
-    });
-
     const ariaTestData: {
         attrName: string,
         propSetter: (x: Combobox, value: string) => void