reference.bib

@article{keenan2013genetics,
  title={Genetics of lipid traits and relationship to coronary artery disease},
  author={Keenan, Tanya E and Rader, Daniel J},
  journal={Current cardiology reports},
  volume={15},
  number={9},
  pages={396},
  year={2013},
  publisher={Springer}
}

@article{bowden2015mendelian,
  title={Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression},
  author={Bowden, Jack and Davey Smith, George and Burgess, Stephen},
  journal={International journal of epidemiology},
  volume={44},
  number={2},
  pages={512--525},
  year={2015},
  publisher={Oxford University Press}
}

@article{burgess2013mendelian,
  title={Mendelian randomization analysis with multiple genetic variants using summarized data},
  author={Burgess, Stephen and Butterworth, Adam and Thompson, Simon G},
  journal={Genetic epidemiology},
  volume={37},
  number={7},
  pages={658--665},
  year={2013},
  publisher={Wiley Online Library}
}

@article{bowden2018improving,
  title={Improving the visualization, interpretation and analysis of two-sample summary data Mendelian randomization via the Radial plot and Radial regression},
  author={Bowden, Jack and Spiller, Wesley and Del Greco M, Fabiola and Sheehan, Nuala and Thompson, John and Minelli, Cosetta and Davey Smith, George},
  journal={International journal of epidemiology},
  volume={47},
  number={4},
  pages={1264--1278},
  year={2018},
  publisher={Oxford University Press}
}

@article{schmidt2017mendelian,
  title={Mendelian randomization with Egger pleiotropy correction and weakly informative Bayesian priors},
  author={Schmidt, AF and Dudbridge, F},
  journal={International journal of epidemiology},
  volume={47},
  number={4},
  pages={1217--1228},
  year={2017},
  publisher={Oxford University Press}
}

@article{zhao2018statistical,
  title={Statistical inference in two-sample summary-data Mendelian randomization using robust adjusted profile score},
  author={Zhao, Qingyuan and Wang, Jingshu and Hemani, Gibran and Bowden, Jack and Small, Dylan S},
  journal={arXiv preprint arXiv:1801.09652},
  year={2018}
}

@article{burgess2015re,
  title={Re:``Multivariable Mendelian randomization: the use of pleiotropic genetic variants to estimate causal effects"},
  author={Burgess, Stephen and Dudbridge, Frank and Thompson, Simon G},
  journal={American journal of epidemiology},
  volume={181},
  number={4},
  pages={290--291},
  year={2015},
  publisher={Oxford University Press}
}

@article{holmes2019ldl,
  title={{What is `LDL cholesterol'?}},
  author={Holmes, Michael V and Ala-Korpela, Mika},
  journal={Nature Reviews Cardiology},
  pages={197--198},
  year={2019},
  volume={16}
}

@article{do2013common,
  title={Common variants associated with plasma triglycerides and risk for coronary artery disease},
  author={Do, Ron and Willer, Cristen J and Schmidt, Ellen M and Sengupta, Sebanti and Gao, Chi and Peloso, Gina M and Gustafsson, Stefan and Kanoni, Stavroula and Ganna, Andrea and Chen, Jin and others},
  journal={Nature genetics},
  volume={45},
  number={11},
  pages={1345},
  year={2013},
  publisher={Nature Publishing Group}
}

@Manual{mrchallenge2019,
    title = {{MRChallenge2019: An R package containing data for the MR Conference Data
Challenge 2019}},
    author = {Wes Spiller and Jack Bowden and Verena Zuber},
    year = {2019},
    note = {R package version 0.1},
	url={https://github.com/WSpiller/MRChallenge2019}
}

@Article{holmesajkd2018,
  title={Challenges in interpreting multivariable Mendelian randomization: Might ``good cholesterol'' be good after all?},
  author={Holmes, M. V. and Davey Smith, G.},
  year = {2018},
  pages = {149--153},
  volume={71},
  number={2}
}

@Manual{twosamplemr,
    title = {{TwoSampleMR: Two Sample MR functions and interface to the MR Base database}},
    author = {Gibran Hemani and Philip Haycock and Jie Zheng and Tom Gaunt and Ben Elsworth},
    year = {2019},
    note = {R package version 0.4.22},
	url={https://github.com/MRCIEU/TwoSampleMR}
}

@Manual{mendelianrandomization,
    title = {{MendelianRandomization: Mendelian Randomization Package}},
    author = {Yavorska, Olena and Staley, James and Burgess, Stephen},
    year = {2019},
    note = {R package version 0.4.1},
    url = {https://CRAN.R-project.org/package=MendelianRandomization},
}

@Article{daveysmith,
  title={{`Mendelian randomization': can genetic epidemiology contribute to understanding environmental determinants of disease?}},
  author={Davey Smith, G. and Ibrahim, S.},
  journal={International Journal of Epidemiology},
  year={2003},
  volume={32},
  number={1},
  pages={1--22}
}

@article{hernan-ss-2019,
author = "Hernán, Miguel A.",
doi = "10.1214/18-STS684",
fjournal = "Statistical Science",
journal = "Statistical Science",
month = "02",
number = "1",
pages = "69--71",
publisher = "The Institute of Mathematical Statistics",
title = "Comment: Spherical Cows in a Vacuum: Data Analysis Competitions for Causal Inference",
url = "https://doi.org/10.1214/18-STS684",
volume = "34",
year = "2019"
}

@article{sanderson-ije-2018,
    author = {Sanderson, Eleanor and Davey Smith, George and Windmeijer, Frank and Bowden, Jack},
    title = "{An examination of multivariable Mendelian randomization in the single-sample and two-sample summary data settings}",
    journal = {International Journal of Epidemiology},
    year = {2018},
    month = {12},
    issn = {0300-5771},
    doi = {10.1093/ije/dyy262},
    url = {https://doi.org/10.1093/ije/dyy262}
}

@article{lotta-plosmed-2016,
    author = {Lotta, Luca A. AND Scott, Robert A. AND Sharp, Stephen J. AND Burgess, Stephen AND Luan, Jian’an AND Tillin, Therese AND Schmidt, Amand F. AND Imamura, Fumiaki AND Stewart, Isobel D. AND Perry, John R. B. AND Marney, Luke AND Koulman, Albert AND Karoly, Edward D. AND Forouhi, Nita G. AND Sjögren, Rasmus J. O. AND Näslund, Erik AND Zierath, Juleen R. AND Krook, Anna AND Savage, David B. AND Griffin, Julian L. AND Chaturvedi, Nishi AND Hingorani, Aroon D. AND Khaw, Kay-Tee AND Barroso, Inês AND McCarthy, Mark I. AND O’Rahilly, Stephen AND Wareham, Nicholas J. AND Langenberg, Claudia},
    journal = {PLOS Medicine},
    publisher = {Public Library of Science},
    title = {{Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis}},
    year = {2016},
    month = {11},
    volume = {13},
    url = {https://doi.org/10.1371/journal.pmed.1002179},
    pages = {1--22},
    number = {11},
    doi = {10.1371/journal.pmed.1002179}
}

@article{holmes-nrg-2017,	
author={Holmes, Michael V. and Ala-Korpela, Mika and Davey Smith, George},
title={{Mendelian randomization in cardiometabolic disease: challenges in evaluating causality}},
journal={Nature Reviews Cardiology},
volume={14},
pages={577--590},
url={https://doi.org/10.1038/nrcardio.2017.78},
doi={10.1038/nrcardio.2017.78},
year={2017}
}

@article{kettunen2016genome,
  title={Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA},
  author={Kettunen, Johannes and Demirkan, Ay{\c{s}}e and W{\"u}rtz, Peter and Draisma, Harmen HM and Haller, Toomas and Rawal, Rajesh and Vaarhorst, Anika and Kangas, Antti J and Lyytik{\"a}inen, Leo-Pekka and Pirinen, Matti and others},
  journal={Nature communications},
  volume={7},
  pages={11122},
  year={2016},
  publisher={Nature Publishing Group}
}

@Manual{spiller-mvmr,
    title = {{MVMR: R package to perform multivariable Mendelian randomization analyses}},
    author = {Wes Spiller and Jack Bowden and Eleanor Sanderson},
    year = {2019},
    note = {R package version 0.1},
    url={https://github.com/WSpiller/MVMR}
  }