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Oct 1, 2021

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1	Biological_Events_of_Oxidative_Stress	Molecular_and_Functional_Categories	Molecule_Enzyme_Protein	MeSH_Heading	MeSH Supplementary	MeSH tree numbers	Chemical Formula	Examples	Pharm Actions	Tree Numbers	References
2	Initiation of Oxidative Stress	Reactive Oxygen Species (ROS)	Superoxide (anion radical)	Superoxides		D01.248.497.158.685.750.850; D01.339.431.374.850; D01.650.550.750.800; D02.38.338.732	O2-	Superoxide, Hydrogen Peroxide	Oxidants	D27.720.642, D27.888.569.540	PMID: 25547488
3	Initiation of Oxidative Stress	Reactive Oxygen Species (ROS)	Hydrogen Peroxide	Hydrogen Peroxide		D01.248.497.158.685.750.424; D01.339.431.374.424; D01.650.550.750.400; D02.38.338.253	H2O2		Anti-Infective Agents, Local	D27.505.954.122.187
4	Initiation of Oxidative Stress	Reactive Oxygen Species (ROS)							Oxidants	D27.720.642, D27.888.569.540
5	Initiation of Oxidative Stress	Reactive Oxygen Species (ROS)	Hydroxyl (radical)	Hydroxyl Radical		D01.339.431.249; D01.248.497.158.459.300; D01.045.250.357	HO		Oxidants	D27.720.642, D27.888.569.540
6	Initiation of Oxidative Stress	Reactive Oxygen Species (ROS)	alpha oxygen	None listed
7	Initiation of Oxidative Stress	Reactive Oxygen Species (ROS)	singlet oxygen	Singlet Oxygen		D01.339.431.500	O2		Oxidants	D27.720.642, D27.888.569.540
8	Initiation of Oxidative Stress	Reactive Oxygen Species (ROS)	Peroxides	Peroxides		D01.248.497.158.685.750; D01.339.431.374; D01.650.550.750; D02.389.338			Oxidants	D27.720.642, D27.888.569.540
9	Initiation of Oxidative Stress	Reactive Oxygen Species (ROS)	Epoxides	Epoxy Compounds		D02.355.291.411	C2H4O, C3H6O, etc.		None listed
10	Initiation of Oxidative Stress	Reactive Nitrogen Species (RNS)	Nitric oxide	Nitric Oxide		D01.339.387; D01.625.550.500; D01.625.700.500; D01.650.550.587.600	NO	Nitric oxide, Peroxynitrite	Bronchodilator Agents	D27.505.696.663.050.110, D27.505.954.796.050.100	PMID: 25547488
11	Initiation of Oxidative Stress	Reactive Nitrogen Species (RNS)							Free Radical Scavengers	D27.505.519.217.500
12	Initiation of Oxidative Stress	Reactive Nitrogen Species (RNS)							Neurotransmitter Agents	D27.505.519.625, D27.505.696.577
13	Initiation of Oxidative Stress	Reactive Nitrogen Species (RNS)							Gasotransmitters	D01.362.282, D27.505.519.625.270
14	Initiation of Oxidative Stress	Reactive Nitrogen Species (RNS)							Endothelium-Dependent Relaxing Factors	D27.505.954.411.918.500
15	Initiation of Oxidative Stress	Reactive Nitrogen Species (RNS)	Nitrogen dioxide	Nitrogen Dioxide		D01.362.635.600; D01.625.550.525; D01.650.550.587.625	NO2		Oxidants, Photochemical	D27.720.642.631, D27.888.569.540.631
16	Initiation of Oxidative Stress	Reactive Nitrogen Species (RNS)	Peroxynitrite	Peroxynitrous Acid		D01.625.600.800; D01.625.700.750	NO3-		None listed
17	Initiation of Oxidative Stress	Lipid peroxide radicals	Lipid peroxyl radicals	Lipid Peroxidation		G02.111.515; G03.295.531.587		polyunsaturated fatty acid (PUFA) peroxide radicals	None listed		PMID: 24999379
18	Initiation of Oxidative Stress	Lipid peroxide radicals		Lipid Peroxides		D01.248.497.158.685.750.637; D01.339.431.374.637; D01.650.550.750.600; D02.389.338.450; D10.440			None listed
19	Initiation of Oxidative Stress	Lipid peroxide radicals	Polyunsaturated fatty acid (PUFA)	Fatty Acids, Unsaturated		D10.251.355			None listed
20	Initiation of Oxidative Stress	Lipid peroxide radicals	Peroxide Radicals	Superoxides		D01.248.497.158.685.750.850; D01.339.431.374.850; D01.650.550.750.800; D02.38.338.732			Oxidants	D27.720.642, D27.888.569.540
21	Initiation of Oxidative Stress	Reactive Aldehydes	4-hydroxy-2-nonenal (4-HNE)	Aldehydes	4-hydroxy-2-nonenal	D02.047	C9H16O2	4-HNE, MDA	Cross-Linking Reagents	D27.720.470.410.210	PMID: 24999379
22	Initiation of Oxidative Stress	Reactive Aldehydes							Cysteine Proteinase Inhibitors	D27.505.519.389.745.325
23	Initiation of Oxidative Stress	Reactive Aldehydes	Malondialdehyde (MDA)	Malondialdehyde		D02.047.700	C3H4O2		None listed
24	Initiation of Oxidative Stress	Reactive Aldehydes	Hydroperoxyfatty acids	Lipid Peroxides		D01.248.497.158.685.750.637; D01.339.431.374.637; D01.650.550.750.600; D02.389.338.450; D10.440			None listed
25	Initiation of Oxidative Stress	Reactive Aldehydes	Aldehydes	Aldehydes		D02.047	RCOH		None listed
26	Initiation of Oxidative Stress	Reactive Aldehydes	conjugated aldehydes	None listed					None listed
27	Initiation of Oxidative Stress	Reactive Aldehydes	4-hydroxynonenal	Aldehydes	4-hydroxy-2-nonenal	D02.047	C9H16O2		Cross-Linking Reagents	D27.720.470.410.210
28	Initiation of Oxidative Stress	Reactive Aldehydes							Cysteine Proteinase Inhibitors	D27.505.519.389.745.325
29	Regulation of Oxidative Stress	Redox Metabolites	Cysteine	Cysteine		D02.886.030.230; D02.886.489.155; D12.125.154.299; D12.125.166.230	C3H7NO2S	Cys/CysSS, GSH/GSSG	None listed
30	Regulation of Oxidative Stress	Redox Metabolites	homocysteine	Homocysteine		D02.886.030.498; D12.125.166.498	C4H9NO2S		None listed
31	Regulation of Oxidative Stress	Redox Metabolites	Glutathione (GSH)	Glutathione		D12.644.456.448	C10H17N3O6S		None listed
32	Regulation of Oxidative Stress	Redox Metabolites	NAD+	NAD		D03.633.100.759.646.138.694; D08.211.589; D13.695.667.138.694; D13.695.827.068.694	C21H28N7O14P2+		None listed
33	Regulation of Oxidative Stress	Redox Metabolites	NADP+	NADP		D03.633.100.759.646.138.749; D08.211.625; D13.695.667.138.749; D13.695.827.068.749	C21H29N7O17P3+		None listed
34	Regulation of Oxidative Stress	Redox Metabolites	FAD	Flavin-Adenine Dinucleotide		D03.633.100.733.315.650.249; D03.633.100.759.646.138.506; D03.633.300.507.650.249; D08.211.474.650.249; D13.695.667.138.506; D13.695.827.068.506; D23.767.405.650.249	C27H33N9O15P2		None listed
35	Regulation of Oxidative Stress	Redox Metabolites	Cystine	Cystine		D01.248.497.158.874.390.369; D01.875.350.850.150.369; D02.886.030.230.369; D02.886.520.150.087; D12.125.095.369; D12.125.119.369; D12.125.166.230.369	C6H12N2O4S2		None listed
36	Regulation of Oxidative Stress	Redox Metabolites	Reduced Glutathione (GSSG, glutathione disulfide)	Glutathione Disulfide		D12.644.456.448.500	C20H32N6O12S2		None listed
37	Regulation of Oxidative Stress	Redox Metabolites	NADH	NAD		D03.633.100.759.646.138.694; D08.211.589; D13.695.667.138.694; D13.695.827.068.694	C21H29N7O14P2		None listed
38	Regulation of Oxidative Stress	Redox Metabolites	NADPH	NADP		D03.633.100.759.646.138.749; D08.211.625; D13.695.667.138.749; D13.695.827.068.749	C21H30N7O17P3		None listed
39	Regulation of Oxidative Stress	Redox Metabolites	FADH2	Flavin-Adenine Dinucleotide	1,5-dihydro-FAD	D03.633.100.733.315.650.249; D03.633.100.759.646.138.506; D03.633.300.507.650.249; D08.211.474.650.249; D13.695.667.138.506; D13.695.827.068.506; D23.767.405.650.249	C27H35N9O15P2		None listed
40	Regulation of Oxidative Stress	Redox Metabolites		5,10-Methylenetetrahydrofolate Reductase (FADH2)		D08.811.682.550
41	Regulation of Oxidative Stress	Redox Metabolites	Quinones	Quinones		D02.806			None listed
42	Regulation of Oxidative Stress	Redox Metabolites	Disulfides	Disulfides		D01.248.497.158.874.390; D01.875.350.850.150; D02.886.520.150			None listed
43	Regulation of Oxidative Stress	Antioxidant Enzymes	Nuclear factor erythroid 2-related factor 2 (nrf2)	NF-E2-Related Factor 2	Nfe2l2 protein, mouse	D12.776.260.108.737; D12.776.930.127.737		GCL, CAT, SOD	None listed
44	Regulation of Oxidative Stress	Antioxidant Enzymes		MafK Transcription Factor	MAFK protein, human	D12.776.260.108.500.500.750; D12.776.260.108.656.750.750; D12.776.260.235.750.750.750; D12.776.930.127.500.500.750; D12.776.930.127.656.750.750; D12.776.930.216.750.750.750			None listed
45	Regulation of Oxidative Stress	Antioxidant Enzymes	Glutamate-cysteine ligase catalytic subunit	Glutamate-Cysteine Ligase	GCLC protein, human	D08.811.464.259.850.400			None listed
46	Regulation of Oxidative Stress	Antioxidant Enzymes	Glutamate-cysteine ligase regulatory subunit	Glutamate-Cysteine Ligase	glutamate-cysteine ligase modifier subunit, human	D08.811.464.259.850.400			None listed
47	Regulation of Oxidative Stress	Antioxidant Enzymes			GCLM protein, mouse				None listed
48	Regulation of Oxidative Stress	Antioxidant Enzymes			GCLM protein, rat				None listed
49	Regulation of Oxidative Stress	Antioxidant Enzymes	NAD(P)H dehydrogenase [quinone] 1	NAD(P)H Dehydrogenase (Quinone)	NQO1 protein, human	D08.811.682.608.800.500			None listed
50	Regulation of Oxidative Stress	Antioxidant Enzymes	Glutathione reductase, mitochondrial	Glutathione Reductase		D08.811.682.667.092			None listed
51	Regulation of Oxidative Stress	Antioxidant Enzymes	Catalase	Catalase		D08.811.682.732.332			Antioxidants	D27.505.519.217, D27.505.696.706.125, D27.720.799.047
52	Regulation of Oxidative Stress	Antioxidant Enzymes	Glutathione S-transferase A1	Glutathione Transferase	GSTA1 protein, human	D08.811.913.225.500			None listed
53	Regulation of Oxidative Stress	Antioxidant Enzymes			glutathione S-transferase alpha				None listed
54	Regulation of Oxidative Stress	Antioxidant Enzymes	Glutathione S-transferase A2	Glutathione Transferase	glutathione S-transferase alpha	D08.811.913.225.500			None listed
55	Regulation of Oxidative Stress	Antioxidant Enzymes		Isoenzymes		D08.811.348; D12.776.800.300			None listed
56	Regulation of Oxidative Stress	Antioxidant Enzymes	Glutathione S-transferase A3	Glutathione Transferase	glutathione S-transferase A3-3, human	D08.811.913.225.500			None listed
57	Regulation of Oxidative Stress	Antioxidant Enzymes	Glutathione S-transferase A4	Glutathione Transferase	leukotriene-C4 synthase	D08.811.913.225.500			None listed
58	Regulation of Oxidative Stress	Antioxidant Enzymes	Glutathione S-transferase Kappa 1	Glutathione Transferase	GSTK1 protein, human	D08.811.913.225.500			None listed
59	Regulation of Oxidative Stress	Antioxidant Enzymes	Glutathione S-transferase Mu 1	Glutathione Transferase	glutathione S-transferase M1	D08.811.913.225.500			None listed
60	Regulation of Oxidative Stress	Antioxidant Enzymes	Glutathione S-transferase Mu 2	Glutathione Transferase	glutathione S-transferase Mu 2	D08.811.913.225.500			None listed
61	Regulation of Oxidative Stress	Antioxidant Enzymes	Glutathione S-transferase Mu 3	Glutathione Transferase	GSTM3 protein, human	D08.811.913.225.500			None listed
62	Regulation of Oxidative Stress	Antioxidant Enzymes			glutathione transferase M3-3				None listed
63	Regulation of Oxidative Stress	Antioxidant Enzymes	Glutathione S-transfease Mu 5	Glutathione Transferase	glutathione S-transferase M5, human	D08.811.913.225.500			None listed
64	Regulation of Oxidative Stress	Antioxidant Enzymes			glutathione S-transferase M5, mouse				None listed
65	Regulation of Oxidative Stress	Antioxidant Enzymes	Glutathione S-transferase Mu 6	None listed
66	Regulation of Oxidative Stress	Antioxidant Enzymes	Glutathione S-transferase Mu 7	None listed
67	Regulation of Oxidative Stress	Antioxidant Enzymes	Glutathione S-transferase P1	Glutathione S-Transferase pi	GSTP1 protein, human	D08.811.913.225.500.500			None listed
68	Regulation of Oxidative Stress	Antioxidant Enzymes			GSTP1 protein, rat				None listed
69	Regulation of Oxidative Stress	Antioxidant Enzymes			GSTP1 protein, mouse				None listed
70	Regulation of Oxidative Stress	Antioxidant Enzymes	Glutathione S-transferase theta-1	Glutathione Transferase	glutathione S-transferase T1	D08.811.913.225.500			None listed
71	Regulation of Oxidative Stress	Antioxidant Enzymes	Glutathione S-transferase theta-2	Glutathione Transferase	GSTT2 protein, human	D08.811.913.225.500			None listed
72	Regulation of Oxidative Stress	Antioxidant Enzymes			GSTT2 protein, rat				None listed
73	Regulation of Oxidative Stress	Antioxidant Enzymes			GSTT2 protein, mouse				None listed
74	Regulation of Oxidative Stress	Antioxidant Enzymes	Microsomal glutathione S-transferase 1	Glutathione Transferase	microsomal glutathione S-transferase-I	D08.811.913.225.500			None listed
75	Regulation of Oxidative Stress	Antioxidant Enzymes	Microsomal glutathione S-transferase 2	Glutathione Transferase	leukotriene-C4 synthase	D08.811.913.225.500			None listed
76	Regulation of Oxidative Stress	Antioxidant Enzymes			MGST2 protein, mouse				None listed
77	Regulation of Oxidative Stress	Antioxidant Enzymes	Microsomal glutathione S-transferase 3	None listed
78	Regulation of Oxidative Stress	Antioxidant Enzymes	Glutathione peroxidase 1	Glutathione Peroxidase	glutathione peroxidase GPX1	D08.811.682.732.500			None listed
79	Regulation of Oxidative Stress	Antioxidant Enzymes	Superoxide dismutase [Cu-Zn]	Superoxide Dismutase		D08.811.682.881			Free Radical Scavengers	D27.505.519.217.500
80	Regulation of Oxidative Stress	Antioxidant Enzymes	Superoxide dismutase [Mn], mitochondrial	Superoxide Dismutase		D08.811.682.881			Free Radical Scavengers	D27.505.519.217.500
81	Regulation of Oxidative Stress	Antioxidant Enzymes	Mitochondrial peptide methionine sulfoxide reductase	Methionine Sulfoxide Reductases	methionine sulfoxide reductase	D08.811.682.730; D12.776.864.100			None listed
82	Regulation of Oxidative Stress	Antioxidant Enzymes	Methionine-R-sulfoxide reductase B1	Methionine Sulfoxide Reductases	methionine sulfoxide reductase	D08.811.682.730; D12.776.864.100			None listed
83	Regulation of Oxidative Stress	Antioxidant Enzymes	Methionine-R-sulfoxide reductase B2	Methionine Sulfoxide Reductases	MSRB2 protein, human	D08.811.682.730; D12.776.864.100			None listed
84	Regulation of Oxidative Stress	Antioxidant Enzymes		Transcription Factors		D12.776.930			None listed
85	Regulation of Oxidative Stress	Antioxidant Enzymes		Oxidoreductases	MSRB2 protein, mouse	D08.811.682			None listed
86	Regulation of Oxidative Stress	Redox Regulating Proteins	Thioredoxin	Thioredoxins		D12.776.915		Thioredoxin, Thioredoxin reductase	None listed
87	Regulation of Oxidative Stress	Redox Regulating Proteins	Thioredoxin, mitochondrial (MTRX) (Mt-Trx) (Thioredoxin-2)	Thioredoxins	Txn2 protein, rat	D12.776.915			None listed
88	Regulation of Oxidative Stress	Redox Regulating Proteins	Thioredoxin-like protein 1	Thioredoxins	TXNL1 protein, human	D12.776.915			None listed
89	Regulation of Oxidative Stress	Redox Regulating Proteins			TXNL1 protein, mouse				None listed
90	Regulation of Oxidative Stress	Redox Regulating Proteins			TXNL1 protein, rat				None listed
91	Regulation of Oxidative Stress	Redox Regulating Proteins	Thioredoxin-like protein 4A	Ribonucleoprotein, U5 Small Nuclear	TXNL4A protein, human	D12.776.157.725.500.875.620; D12.776.157.725.829.375; D12.776.664.962.500.875.620; D12.776.664.962.829.375			None listed
92	Regulation of Oxidative Stress	Redox Regulating Proteins	Thioredoxin-like protein 4B	Nuclear Proteins	TXNL4B protein, human	D12.776.660			None listed
93	Regulation of Oxidative Stress	Redox Regulating Proteins		Cell Cycle Proteins		D12.776.167			None listed
94	Regulation of Oxidative Stress	Redox Regulating Proteins	Thioredoxin reductase 1, cytoplasmic (TR) (EC 1.8.1.9) (Thioredoxin reductase TR1)	Thioredoxin Reductase 1	TXNRD1 protein, human	D08.811.682.667.750.500			None listed
95	Regulation of Oxidative Stress	Redox Regulating Proteins			TXNRD1 protein, mouse				None listed
96	Regulation of Oxidative Stress	Redox Regulating Proteins			TXNRD1 protein, rat				None listed
97	Regulation of Oxidative Stress	Redox Regulating Proteins	Thioredoxin reductase 2, mitochondrial (EC 1.8.1.9) (Thioredoxin reductase TR3)	Thioredoxin Reductase 2	TXNRD2 protein, human	D08.811.682.667.750.750			None listed
98	Regulation of Oxidative Stress	Redox Regulating Proteins			TXNRD2 protein, mouse				None listed
99	Regulation of Oxidative Stress	Redox Regulating Proteins			TXNRD2 protein, rat				None listed
100	Regulation of Oxidative Stress	Redox Regulating Proteins	Thioredoxin reductase 3 (EC 1.8.1.9) (Thioredoxin and glutathione reductase) (Thioredoxin reductase TR2)	Thioredoxin-Disulfide Reductase	TXNRD3 protein, human	D08.811.682.667.750; D12.776.331.971			None listed
101	Regulation of Oxidative Stress	Redox Regulating Proteins		Glutathione Reductase	Txnrd3 protein, mouse	D08.811.682.667.092			None listed
102	Regulation of Oxidative Stress	Redox Regulating Proteins	Thioredoxin-interacting protein (Thioredoxin domain-containing protein 1)	Carrier Proteins	TXNIP protein, rat	D12.776.157			None listed
103	Regulation of Oxidative Stress	Redox Regulating Proteins			TXNIP protein, human				None listed
104	Regulation of Oxidative Stress	Redox Regulating Proteins	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4)	Membrane Proteins	TXNDC2 protein, human	D12.776.543			None listed
105	Regulation of Oxidative Stress	Redox Regulating Proteins		Thioredoxins		D12.776.915			None listed
106	Regulation of Oxidative Stress	Redox Regulating Proteins		Membrane Proteins	Txndc2 protein, mouse	D12.776.543			None listed
107	Regulation of Oxidative Stress	Redox Regulating Proteins		Thioredoxins		D12.776.915			None listed
108	Regulation of Oxidative Stress	Redox Regulating Proteins	Thioredoxin domain-containing protein 3 (NME/NM23 family member 8) (Spermatid-specific thioredoxin-2) (Sptrx-2)	Thioredoxins	NME8 protein, human	D12.776.915			None listed
109	Regulation of Oxidative Stress	Redox Regulating Proteins		Seminal Plasma Proteins	SPTRX-2 protein, rat	D12.776.866			None listed
110	Regulation of Oxidative Stress	Redox Regulating Proteins			SPTRX-2 protein, mouse				None listed
111	Regulation of Oxidative Stress	Redox Regulating Proteins	Thioredoxin domain-containing protein 5 (Endoplasmic reticulum resident protein 46) (ER protein 46) (ERp46) (Plasma cell-specific thioredoxin-related protein) (PC-TRP) (Thioredoxin-like protein p46)	Thioredoxins	PC-TRP protein, mouse	D12.776.915			None listed
112	Regulation of Oxidative Stress	Redox Regulating Proteins	Thioredoxin domain-containing protein 8 (Spermatid-specific thioredoxin-3) (Sptrx-3) (Thioredoxin-6)	Thioredoxins	TXNDC8 protein, human	D12.776.915			None listed
113	Regulation of Oxidative Stress	Redox Regulating Proteins	Thioredoxin domain-containing protein 9 (ATP-binding protein associated with cell differentiation)	Nuclear Proteins	Txndc9 protein, mouse	D12.776.660			None listed
114	Regulation of Oxidative Stress	Redox Regulating Proteins	Thioredoxin domain-containing protein 11	Carrier Proteins	TXNDC11 protein, human	D12.776.157			None listed
115	Regulation of Oxidative Stress	Redox Regulating Proteins	Thioredoxin domain-containing protein 12 (EC 1.8.4.2) (Endoplasmic reticulum resident protein 19) (ER protein 19) (ERp19) (Thioredoxin-like protein p19)	Protein Disulfide Reductase (Glutathione)	TXNDC12 protein, human	D08.811.682.667.186			None listed
116	Regulation of Oxidative Stress	Redox Regulating Proteins	Thioredoxin-related transmembrane protein 4 (Thioredoxin domain-containing protein 13) (TMX4)	Membrane Glycoproteins	TMX4 protein, human	D12.776.395.550; D12.776.543.550			None listed
117	Regulation of Oxidative Stress	Redox Regulating Proteins		Protein Disulfide Reductase (Glutathione)		D08.811.682.667.186			None listed
118	Regulation of Oxidative Stress	Redox Regulating Proteins	Thioredoxin-related transmembrane protein 2 (Thioredoxin domain-containing protein 14) (TMX2)	Membrane Proteins	TMX2 protein, human	D12.776.543			None listed
119	Regulation of Oxidative Stress	Redox Regulating Proteins		Thioredoxins		D12.776.915			None listed
120	Regulation of Oxidative Stress	Redox Regulating Proteins	Thioredoxin domain-containing protein 15	None listed
121	Regulation of Oxidative Stress	Redox Regulating Proteins	Thioredoxin domain-containing protein 16	Antigens, Neoplasm	TXNDC16 protein, human	D23.050.285			None listed
122	Regulation of Oxidative Stress	Redox Regulating Proteins		Membrane Glycoproteins		D12.776.395.550; D12.776.543.550			None listed
123	Regulation of Oxidative Stress	Redox Regulating Proteins	Thioredoxin domain-containing protein 17 (14 kDa thioredoxin-related protein) (TRP14) (Protein 42-9-9) (Thioredoxin-like protein 5)	Thioredoxins	TXNDC17 protein, human	D12.776.915			None listed
124	Regulation of Oxidative Stress	Redox Regulating Proteins	Peroxiredoxin-1 (EC 1.11.1.15) (Macrophage 23 kDa stress protein) (Osteoblast-specific factor 3) (OSF-3) (Thioredoxin peroxidase 2) (Thioredoxin-dependent peroxide reductase 2)	Peroxiredoxins	PRDX1 protein, human	D08.811.682.732.850			None listed
125	Regulation of Oxidative Stress	Redox Regulating Proteins			PRDX1 protein, mouse				None listed
126	Regulation of Oxidative Stress	Redox Regulating Proteins			PRDX1 protein, rat				None listed
127	Regulation of Oxidative Stress	Redox Regulating Proteins	Peroxiredoxin-2 (EC 1.11.1.15) (Thiol-specific antioxidant protein) (TSA) (Thioredoxin peroxidase 1) (Thioredoxin-dependent peroxide reductase 1)	Peroxiredoxins	PRDX2 protein, human	D08.811.682.732.850			None listed
128	Regulation of Oxidative Stress	Redox Regulating Proteins			PRDX2 protein, mouse				None listed
129	Regulation of Oxidative Stress	Redox Regulating Proteins	Thioredoxin-dependent peroxide reductase, mitochondrial (EC 1.11.1.15) (Antioxidant protein 1) (AOP-1) (PRX III) (Perioredoxin-3) (Protein MER5)	Peroxiredoxin III		D08.811.682.732.850.249			None listed
130	Regulation of Oxidative Stress	Redox Regulating Proteins		Peroxiredoxin III	PRDX3 protein, human	D08.811.682.732.850.249			None listed
131	Regulation of Oxidative Stress	Redox Regulating Proteins			PRDX3 protein, mouse	D08.811.682.732.850.249			None listed
132	Regulation of Oxidative Stress	Redox Regulating Proteins	Peroxiredoxin-4 (EC 1.11.1.15) (Antioxidant enzyme AOE372) (Peroxiredoxin IV) (Prx-IV) (Thioredoxin peroxidase AO372) (Thioredoxin-dependent peroxide reductase A0372)	Peroxiredoxins		D08.811.682.732.850			None listed
133	Regulation of Oxidative Stress	Redox Regulating Proteins		Peroxiredoxins	PRDX4 protein, human	D08.811.682.732.850			None listed
134	Regulation of Oxidative Stress	Redox Regulating Proteins			PRDX4 protein, mouse	D08.811.682.732.850			None listed
135	Regulation of Oxidative Stress	Redox Regulating Proteins			PRDX4 protein, rat	D08.811.682.732.850			None listed
136	Regulation of Oxidative Stress	Redox Regulating Proteins	Peroxiredoxin-5, mitochondrial (EC 1.11.1.15) (Antioxidant enzyme B166) (AOEB166) (Liver tissue 2D-page spot 2D-0014IV) (PLP) (Peroxiredoxin V) (Prx-V) (Peroxisomal antioxidant enzyme) (Thioredoxin peroxidase PMP20)	Peroxiredoxins		D08.811.682.732.850			None listed
137	Regulation of Oxidative Stress	Redox Regulating Proteins		Peroxiredoxins	PRDX5 protein, human	D08.811.682.732.850			None listed
138	Regulation of Oxidative Stress	Redox Regulating Proteins			PRDX5 protein, mouse	D08.811.682.732.850			None listed
139	Regulation of Oxidative Stress	Redox Regulating Proteins	Peroxiredoxin-6 (EC 1.11.1.15) (1-Cys peroxiredoxin) (1-Cys PRX) (Acidic calcium-independent phospholipase A2) (aiPLA2) (EC 3.1.1.4) (Antioxidant protein 2) (Non-selenium glutathione peroxidase) (NSGPx)	Peroxiredoxin VI		D08.811.277.352.100.680.750.937.300.500; D08.811.277.352.100.680.750.937.625.624; D08.811.641.773; D08.811.682.732.850.500			None listed
140	Regulation of Oxidative Stress	Redox Regulating Proteins			PRDX6 protein, human				None listed
141	Regulation of Oxidative Stress	Redox Regulating Proteins			PRDX6 protein, mouse				None listed
142	Regulation of Oxidative Stress	Redox Regulating Proteins			PRDX6 protein, rat
143	Regulation of Oxidative Stress	Redox Regulating Proteins	Peroxiredoxin-like 2A (Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes) (Protein PAMM) (Redox-regulatory protein FAM213A)	None listed
144	Regulation of Oxidative Stress	Redox Regulating Proteins	Prostamide/prostaglandin F synthase (Prostamide/PG F synthase) (Prostamide/PGF synthase) (EC 1.11.1.20) (Peroxiredoxin-like 2B)	None listed
145	Regulation of Oxidative Stress	Redox Regulating Proteins	Peroxiredoxin-like 2C (AhpC/TSA antioxidant enzyme domain-containing protein 1) (Thioredoxin-like protein AAED1)	None listed
146	Regulation of Oxidative Stress	Redox Regulating Proteins	Nucleoredoxin (EC 1.8.1.8) (Protein Red-1)	Nuclear Proteins	nucleoredoxin	D12.776.660			None listed
147	Regulation of Oxidative Stress	Redox Regulating Proteins		Oxidoreductases		D08.811.682			None listed
148	Regulation of Oxidative Stress	Redox Regulating Proteins	Nucleoredoxin-like protein 1 (Rod-derived cone viability factor) (RdCVF) (Thioredoxin-like protein 6)	Thioredoxins	NXNL1 protein, human	D12.776.915			None listed
149	Regulation of Oxidative Stress	Redox Regulating Proteins	Nucleoredoxin-like protein 2 (Rod-derived cone viability factor 2) (RdCVF2)	None listed
150	Regulation of Oxidative Stress	Redox Regulating Proteins	Sulfiredoxin-1	Oxidoreductases Acting on Sulfur Group Donors	Srxn1 protein, rat	D08.811.682.667			None listed
151	Regulation of Oxidative Stress	Redox Regulating Proteins			SRXN1 protein, human				None listed
152	Regulation of Oxidative Stress	Redox Regulating Proteins	Glutaredoxin-1 (thioltransferase-1) (Ttase-1)	Glutaredoxins		D08.811.682.667.084			None listed
153	Regulation of Oxidative Stress	Redox Regulating Proteins		Glutaredoxins	Glrx1 protein, rat	D08.811.682.667.084			None listed
154	Regulation of Oxidative Stress	Redox Regulating Proteins	Glutaredoxin-2, mitochondrial	Glutaredoxins	GLRX2 protein, human	D08.811.682.667.084			None listed
155	Regulation of Oxidative Stress	Redox Regulating Proteins			GLRX2 protein, mouse				None listed
156	Regulation of Oxidative Stress	Redox Regulating Proteins			GLRX2 protein, rat				None listed
157	Regulation of Oxidative Stress	Redox Regulating Proteins	Glutaredoxin-3 (PKC-interacting cousin of thioredoxin) (PICOT) (PKC-theta-interacting protein) (PKCq-interacting protein) (Thioredoxin-like protein 2)	Carrier Proteins	GLRX3 protein, human	D12.776.157			None listed
158	Regulation of Oxidative Stress	Redox Regulating Proteins	Glutaredoxin-related protein 5, mitochondrial (Monothiol glutaredoxin-5)	Glutaredoxins	GLRX5 protein, human	D08.811.682.667.084			None listed
159	Regulation of Oxidative Stress	Redox Regulating Proteins			GLRX5 protein, mouse				None listed
160	Regulation of Oxidative Stress	Redox Regulating Proteins	Glutaredoxin domain-containing cysteine-rich protein 1	Glutaredoxins	GRXCR1 protein, human	D08.811.682.667.084			None listed
161	Regulation of Oxidative Stress	Redox Regulating Proteins			GRXCR1 protein, mouse				None listed
162	Regulation of Oxidative Stress	Redox Regulating Proteins	Protein disulfide-isomerase (PDI) (EC 5.3.4.1) (Cellular thyroid hormone-binding protein) (Endoplasmic reticulum resident protein 59) (ER protein 59) (ERp59) (Prolyl 4-hydroxylase subunit beta) (p55)	Protein Disulfide-Isomerases		D08.811.399.475.800.550			None listed
163	Regulation of Oxidative Stress	Redox Regulating Proteins		Procollagen-Proline Dioxygenase	P4HB protein, human	D08.811.682.690.416.617.750; D08.811.682.690.708.694.750			None listed
164	Regulation of Oxidative Stress	Redox Regulating Proteins	Protein disulfide-isomerase A2 (EC 5.3.4.1) (PDIp)	Protein Disulfide-Isomerases	PDIA2 protein, human	D08.811.399.475.800.550			None listed
165	Regulation of Oxidative Stress	Redox Regulating Proteins	Protein disulfide-isomerase A3 (EC 5.3.4.1) (58 kDa glucose-regulated protein) (58 kDa microsomal protein) (p58) (Disulfide isomerase ER-60) (Endoplasmic reticulum resident protein 57) (ER protein 57) (ERp57) (Endoplasmic reticulum resident protein 60) (ER protein 60) (ERp60)	Protein Disulfide-Isomerases	PDIA3 protein, human	D08.811.399.475.800.550			None listed
166	Regulation of Oxidative Stress	Redox Regulating Proteins			PDIA3 protein, mouse				None listed
167	Regulation of Oxidative Stress	Redox Regulating Proteins			Grp58 protein, rat				None listed
168	Regulation of Oxidative Stress	Redox Regulating Proteins	Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72)	Protein Disulfide-Isomerases	PDIA4 protein, human	D08.811.399.475.800.550			None listed
169	Regulation of Oxidative Stress	Redox Regulating Proteins			Pdia4 protein, mouse				None listed
170	Regulation of Oxidative Stress	Redox Regulating Proteins	Protein disulfide-isomerase A5 (EC 5.3.4.1) (Protein disulfide isomerase-related protein)	Protein Disulfide-Isomerases	PDIA5 protein, human	D08.811.399.475.800.550			None listed
171	Regulation of Oxidative Stress	Redox Regulating Proteins			Pdia5 protein, mouse				None listed
172	Regulation of Oxidative Stress	Redox Regulating Proteins	Protein disulfide-isomerase A6 (EC 5.3.4.1) (Thioredoxin domain-containing protein 7)	Protein Disulfide-Isomerases	PDIA6 protein, human	D08.811.399.475.800.550			None listed
173	Regulation of Oxidative Stress	Redox Regulating Proteins			PDIA6 protein, mouse				None listed
174	Regulation of Oxidative Stress	Redox Regulating Proteins	Protein disulfide-isomerase-like protein of the testis	Protein Disulfide-Isomerases	PDILT protein, human	D08.811.399.475.800.550			None listed
175	Regulation of Oxidative Stress	Redox Regulating Proteins			Pdilt protein, mouse				None listed
176	Regulation of Oxidative Stress	Redox Regulating Proteins	Selenoprotein W (SelW)	Selenoprotein W		D12.776.864.500			None listed
177	Regulation of Oxidative Stress	Redox Regulating Proteins		Selenoprotein W	SEPW1 protein, human	D12.776.864.500			None listed
178	Regulation of Oxidative Stress	Redox Regulating Proteins	Thioredoxin reductase-like selenoprotein T (SelT) (EC 1.8.1.9)	Selenoproteins	SELT protein, human	D12.776.864			None listed
179	Regulation of Oxidative Stress	Redox Regulating Proteins			selenoprotein T, mouse				None listed
180	Regulation of Oxidative Stress	Redox Regulating Proteins	Selenoprotein M (SelM)	Selenoproteins	SELM protein, human	D12.776.864			None listed
181	Regulation of Oxidative Stress	Redox Regulating Proteins	Selenoprotein H (SelH)	DNA-Binding Proteins	selenoprotein H, human	D12.776.260			None listed
182	Regulation of Oxidative Stress	Redox Regulating Proteins		Selenoproteins	selenoprotein H, mouse	D12.776.864			None listed
183	Regulation of Oxidative Stress	Redox Regulating Proteins			selenoprotein H, rat				None listed
184	Regulation of Oxidative Stress	Redox Regulating Proteins	Selenoprotein F (15 kDa selenoprotein)	Selenoproteins	SELENOF protein, human	D12.776.864			None listed
185	Regulation of Oxidative Stress	Redox Regulating Proteins	Mitochondrial peptide methionine sulfoxide reductase (EC 1.8.4.11) (Peptide-methionine (S)-S-oxide reductase) (Peptide Met(O) reductase) (Protein-methionine-S-oxide reductase) (PMSR)	Methionine Sulfoxide Reductases	methionine sulfoxide reductase	D08.811.682.730; D12.776.864.100			None listed
186	Regulation of Oxidative Stress	Redox Regulating Proteins	Methionine-R-sulfoxide reductase B1 (MsrB1) (EC 1.8.4.12) (EC 1.8.4.14) (Selenoprotein R) (SelR) (Selenoprotein X) (SelX)	Methionine Sulfoxide Reductases	methionine sulfoxide reductase	D08.811.682.730; D12.776.864.100			None listed
187	Regulation of Oxidative Stress	Redox Regulating Proteins			MsrB1 protein, mouse				None listed
188	Regulation of Oxidative Stress	Redox Regulating Proteins	Methionine-R-sulfoxide reductase B2, mitochondrial (MsrB2) (EC 1.8.4.12) (EC 1.8.4.14)		MSRB2 protein, human	D12.776.930			None listed
189	Regulation of Oxidative Stress	Redox Regulating Proteins		Methionine Sulfoxide Reductases		D08.811.682.730; D12.776.864.100			None listed
190	Regulation of Oxidative Stress	Redox Regulating Proteins		Oxidoreductases	MSRB2 protein, mouse	D08.811.682			None listed
191	Regulation of Oxidative Stress	Redox Regulating Proteins	Methionine-R-sulfoxide reductase B3, mitochondrial (MsrB3) (EC 1.8.4.12) (EC 1.8.4.14)	Methionine Sulfoxide Reductases	MSRB3 protein, human	D08.811.682.730; D12.776.864.100			None listed
192	Regulation of Oxidative Stress	Redox Regulating Proteins		Methionine Sulfoxide Reductases	methionine sulfoxide reductase B3, mouse	D08.811.682.730; D12.776.864.100			None listed
193	Regulation of Oxidative Stress	Antioxidants	vitamin E (alpha tocopherol)	Vitamin E		D03.383.663.283.909; D03.633.100.150.909	C29H50O2		Antioxidants	D27.505.519.217, D27.505.696.706.125, D27.720.799.047
194	Regulation of Oxidative Stress	Antioxidants							Vitamins	D27.505.696.377.683.500.600, G07.203.300.681.500.600, J02.500.681.500.600
195	Regulation of Oxidative Stress	Antioxidants	tocopherol	Tocopherols		D03.383.663.283.909.750;D03.633.100.150.909.750			Antioxidants	D27.505.519.217, D27.505.696.706.125, D27.720.799.047
196	Regulation of Oxidative Stress	Antioxidants							Vitamins	D27.505.696.377.683.500.600, G07.203.300.681.500.600, J02.500.681.500.600
197	Regulation of Oxidative Stress	Antioxidants	tocotrienol	Tocotrienols		D03.383.663.283.909.875; D03.633.100.150.909.875			Antioxidants	D27.505.519.217, D27.505.696.706.125, D27.720.799.047
198	Regulation of Oxidative Stress	Antioxidants							Vitamins	D27.505.696.377.683.500.600, G07.203.300.681.500.600, J02.500.681.500.600
199	Regulation of Oxidative Stress	Antioxidants	vitamin A (retinol)	Vitamin A		D02.455.326.271.665.202.495.818; D02.455.426.392.368.367.379.249.700.860; D02.455.849.131.495.818; D23.767.261.700.860	C20H30O		Vitamins	D27.505.696.377.683.500.600, G07.203.300.681.500.600, J02.500.681.500.600
200	Regulation of Oxidative Stress	Antioxidants	vitamin C (ascorbic acid)	Ascorbic Acid		D02.241.081.844.107; D02.241.511.902.107; D09.811.100	C6H8O6		Antioxidants	D27.505.519.217, D27.505.696.706.125, D27.720.799.047
201	Regulation of Oxidative Stress	Antioxidants							Vitamins	D27.505.696.377.683.500.600, G07.203.300.681.500.600, J02.500.681.500.600
202	Regulation of Oxidative Stress	Antioxidants	ascorbic acid	Ascorbic Acid		D02.241.081.844.107; D02.241.511.902.107; D09.811.100	C6H8O6		Antioxidants	D27.505.519.217, D27.505.696.706.125, D27.720.799.047