diff --git a/docs/changelog.md b/docs/changelog.md index 8f2ed084..d6104f2b 100644 --- a/docs/changelog.md +++ b/docs/changelog.md @@ -4,6 +4,26 @@ This page lists changes for the [Beacon+](http://beacon.progenetix.org/ui/) implementation of the ["Beacon" genomics API](http://beacon-project.io), as well as related updates for the [Progenetix](http://progenetix.org) front-end. +## 2024-09-10: Ongoing removal of samples from pure germline series + +So far of the currently 145264 samples the Progenetix collection consisted of +besides data from + +* 112674 cancer samples (including primary tumors, recurrences and metastases) +* 5742 cancer cell line samples +* 26848 germline samples consisting of + - germline references of tumor patients + - 3201 reference profiles from the 1000 genomes project + - samples from 58 "accidental" germline series (_i.e._ such being analyzed + in automated download & processing and then being kept for comparative purposes) + +We are now in the process of creating a new resource for the germline samples +which will become available in the near future under the [refcnv.org](https://refcnv.org) +address. While strengthening the focus of the Progenetix database this will provide +a new general resource for germline CNV data e.g. as reference for rare disease +applications. + + ## 2024-06-18 Switching ontology use for `individual.sex` While we had previously used the PATO terms for `genotypic sex` (PATO:0020001