Marge has just one E-Mail-addresses she is using. She likes to keep the Mails on an IMAP-Server. She use her Mailboxes via Web Interface and neomutt via direct access to IMAP
Milhouse don't like IMAP. He has a lot of e-mail-addresses. He has subscribed a lot of mailinglist. He use getmail + procmail + notmuch.
Bart is using isync.
Homer is using two IMAP Accounts.