diff --git a/bindgen/clang.rs b/bindgen/clang.rs
index 3438bfa2c4..4a4ed89d69 100644
--- a/bindgen/clang.rs
+++ b/bindgen/clang.rs
@@ -2297,6 +2297,15 @@ impl Drop for EvalResult {
         unsafe { clang_EvalResult_dispose(self.x) };
     }
 }
+/// ABI kinds as defined in
+/// <https://github.com/llvm/llvm-project/blob/ddf1de20a3f7db3bca1ef6ba7e6cbb90aac5fd2d/clang/include/clang/Basic/TargetCXXABI.def>
+#[derive(Debug, Eq, PartialEq, Copy, Clone)]
+pub(crate) enum ABIKind {
+    /// All the regular targets like Linux, Mac, WASM, etc. implement the Itanium ABI
+    GenericItanium,
+    /// The ABI used when compiling for the MSVC target
+    Microsoft,
+}
 
 /// Target information obtained from libclang.
 #[derive(Debug)]
@@ -2305,6 +2314,8 @@ pub(crate) struct TargetInfo {
     pub(crate) triple: String,
     /// The width of the pointer _in bits_.
     pub(crate) pointer_width: usize,
+    /// The ABI of the target
+    pub(crate) abi: ABIKind,
 }
 
 impl TargetInfo {
@@ -2320,9 +2331,17 @@ impl TargetInfo {
         }
         assert!(pointer_width > 0);
         assert_eq!(pointer_width % 8, 0);
+
+        let abi = if triple.contains("msvc") {
+            ABIKind::Microsoft
+        } else {
+            ABIKind::GenericItanium
+        };
+
         TargetInfo {
             triple,
             pointer_width: pointer_width as usize,
+            abi,
         }
     }
 }
diff --git a/bindgen/ir/context.rs b/bindgen/ir/context.rs
index 11048b70c8..517d3365b6 100644
--- a/bindgen/ir/context.rs
+++ b/bindgen/ir/context.rs
@@ -19,7 +19,7 @@ use super::module::{Module, ModuleKind};
 use super::template::{TemplateInstantiation, TemplateParameters};
 use super::traversal::{self, Edge, ItemTraversal};
 use super::ty::{FloatKind, Type, TypeKind};
-use crate::clang::{self, Cursor};
+use crate::clang::{self, ABIKind, Cursor};
 use crate::codegen::CodegenError;
 use crate::BindgenOptions;
 use crate::{Entry, HashMap, HashSet};
@@ -626,6 +626,11 @@ If you encounter an error missing from this list, please file an issue or a PR!"
         self.target_info.pointer_width / 8
     }
 
+    /// Returns the ABI, which is mostly useful for determining the mangling kind.
+    pub(crate) fn abi_kind(&self) -> ABIKind {
+        self.target_info.abi
+    }
+
     /// Get the stack of partially parsed types that we are in the middle of
     /// parsing.
     pub(crate) fn currently_parsed_types(&self) -> &[PartialType] {
diff --git a/bindgen/ir/function.rs b/bindgen/ir/function.rs
index 6342758f9f..6679a3d509 100644
--- a/bindgen/ir/function.rs
+++ b/bindgen/ir/function.rs
@@ -7,7 +7,7 @@ use super::item::Item;
 use super::traversal::{EdgeKind, Trace, Tracer};
 use super::ty::TypeKind;
 use crate::callbacks::{ItemInfo, ItemKind};
-use crate::clang::{self, Attribute};
+use crate::clang::{self, ABIKind, Attribute};
 use crate::parse::{ClangSubItemParser, ParseError, ParseResult};
 use clang_sys::{self, CXCallingConv};
 
@@ -324,11 +324,12 @@ pub(crate) fn cursor_mangling(
         return None;
     }
 
+    let is_itanium_abi = ctx.abi_kind() == ABIKind::GenericItanium;
     let is_destructor = cursor.kind() == clang_sys::CXCursor_Destructor;
     if let Ok(mut manglings) = cursor.cxx_manglings() {
         while let Some(m) = manglings.pop() {
             // Only generate the destructor group 1, see below.
-            if is_destructor && !m.ends_with("D1Ev") {
+            if is_itanium_abi && is_destructor && !m.ends_with("D1Ev") {
                 continue;
             }
 
@@ -341,7 +342,7 @@ pub(crate) fn cursor_mangling(
         return None;
     }
 
-    if is_destructor {
+    if is_itanium_abi && is_destructor {
         // With old (3.8-) libclang versions, and the Itanium ABI, clang returns
         // the "destructor group 0" symbol, which means that it'll try to free
         // memory, which definitely isn't what we want.